Cryotube with mesh sample holder

By designing cryovials with mesh sample holders, the problems of inconvenient sample placement and slippage due to damage in existing cryovials have been solved, achieving better freezing effect and liquid nitrogen flowability, and making them suitable for various sample sizes.

CN224672739UActive Publication Date: 2026-08-25YANTAI YUHUANGDING HOSPITAL
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Patent Information

Application Number
CN202522066728.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-09-25
Publication Date
2026-08-25
Estimated Expiration
2035-09-25

AI Technical Summary

Technical Problem

The existing cryopreservation tubes are not convenient for placing sample tissues and there is a risk of damage or slippage, which affects the freezing effect.

Method used

Design a cryopreservation tube with a mesh sample holder. The mesh sample holder is made of titanium alloy material. The mesh body has evenly distributed transparent holes. It is embedded in the inner hole of the tube cap through columnar bodies to ensure that the sample tissue has a large contact area with liquid nitrogen and is not easy to fall off.

Benefits of technology

It improves the freezing effect of sample tissues, enhances the flowability of liquid nitrogen, avoids damage and slippage of sample tissues, and is suitable for samples of different sizes.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to a cryopreservation tube with netted sample bracket belongs to biological experiment appliance structure technical field. It includes pipe body and pipe cover, and the inner thread is equipped in pipe body upper mouth inboard, and the outer thread is equipped in pipe cover lower extreme, and pipe body is connected with pipe cover through thread screwing, and the sealing rubber ring is equipped in pipe body and pipe cover interface department, and the cylindrical inner hole is equipped with pipe cover lower part, and the netted sample bracket is equipped in inner hole, and the netted sample bracket is by the integral type structure of columnar body and netted body, and the columnar body is located netted sample bracket one end, and the outer diameter of columnar body cooperates with the inner diameter of pipe cover lower part inner hole, and the netted sample bracket is connected with pipe cover embeddedly through columnar body, and the specimen tissue is placed on the net surface of netted body. Because the netted body structure lets liquid nitrogen flowability strengthen, the sample and liquid nitrogen contact area are big, make the sample freezing effect better, and because the sample and the contact area of netted sample bracket are bigger, the specimen tissue is not easy to fall off, and the mesh of netted body is relatively dense, and can be applicable to different size sample tissue freezing.
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Description

Technical Field

[0001] This utility model relates to a cryopreservation tube for storing biological samples at low temperatures, belonging to the technical field of biological experimental apparatus structure. Background Technology

[0002] In industries such as biology, medicine, vaccines, human gene banks, and food, cryovials are used to store a range of samples, including cells, rare samples, and genes, achieving low-temperature preservation. Currently, cryovials use either needle-shaped or sheet-shaped holders for placing samples. Needle-shaped holders are inconvenient for placing larger tissue specimens, and the fine needle tips can easily damage the specimens. Sheet-shaped holders, on the other hand, can hinder the flow of cryogenic fluid, thus affecting the freezing effect, and the tissue may also slip off the sheet-shaped holder, causing inconvenience during handling. Summary of the Invention

[0003] The purpose of this invention is to solve the problem that the placement of sample tissues in existing cryopreservation tubes is not convenient and safe, and to provide a cryopreservation tube with a scientific and reasonable structure, convenient operation, and a mesh sample holder. This utility model is achieved through the following technical solution: A cryopreservation tube with a mesh sample holder includes a tube body and a cap. The tube body has an internal thread on the inner side of its upper opening, and the cap has an external thread at its lower end. The tube body and the cap are connected by screwing on the threads. A sealing rubber ring is installed at the interface between the tube body and the cap. The tube body is characterized by a cylindrical inner hole at the lower part of the cap, in which a mesh sample holder is connected. The mesh sample holder is composed of columnar bodies and mesh bodies, which are integrated into one structure. The mesh body has evenly distributed perforated mesh holes on its plane. The columnar bodies are located at one end of the mesh sample holder, and the outer diameter of the columnar bodies matches the inner diameter of the inner hole at the lower part of the cap. The mesh sample holder is tightly connected to the inner hole of the cap through the columnar bodies, and the specimen tissue is placed on the mesh surface.

[0004] The length and width of the mesh sample holder are matched with the depth and inner diameter of the cryopreservation tube, and the widest part of the mesh opening is less than or equal to 1 mm.

[0005] The outer surface of the tube is marked with a capacity scale, which makes it convenient for users to control the addition of coolant inside the tube.

[0006] The outer surface of the tube is also provided with a sample identification recording area to mark the number of the sample tissue inside the cryopreservation tube.

[0007] The mesh sample holder is made of titanium alloy to avoid damaging the specimen tissue.

[0008] This utility model has a scientific and reasonable structure. It uses a mesh sample holder to place sample tissues. The mesh structure enhances the fluidity of liquid nitrogen, resulting in a larger contact area between the sample tissues and liquid nitrogen, and thus a better freezing effect. At the same time, due to the larger contact area between the sample tissues and the mesh sample holder, the micro-roughness formed by the mesh pores on the mesh surface makes the sample tissues less likely to fall off. Moreover, because the mesh pores are relatively dense, it can be used to freeze sample tissues of different sizes. Attached Figure Description

[0009] Figure 1 : This is a schematic diagram of the structure of this utility model; Figure 2 : A partial sectional view of the pipe cap and rubber ring; Figure 3 : Schematic diagram of the mesh sample holder structure; Figure 4 :for Figure 3 The left view; In the diagram: 1. Tube body, 1-1. Volume scale markings, 1-2. Sample identification and recording area, 2. Tube cap, 2-1. Inner hole, 3. Mesh sample holder, 3-1. Columnar body, 3-2. Mesh body, 4. Rubber ring. Detailed Implementation

[0010] The following detailed embodiments of the present invention are given with reference to the accompanying drawings, which are used to further illustrate the structure of the present invention.

[0011] The cryovial with a mesh sample holder in this embodiment is shown in the attached image. Figure 1 As shown, it includes a pipe body 1 and a pipe cap 2. The inner side of the upper opening of the pipe body 1 is provided with internal threads, and the lower end of the pipe cap 2 is provided with external threads. The pipe body and the pipe cap are connected by screwing on the threads. A sealing rubber ring 4 is installed at the interface between the pipe body and the pipe cap. The feature is that the lower part of the pipe cap 2 is provided with a cylindrical inner hole 2-1, as shown in the attached figure. Figure 2 As shown, a mesh sample holder 3 is installed in the inner hole. The mesh sample holder 3 is composed of columnar bodies 3-1 and mesh bodies 3-2, as shown in the attached figure. Figure 3 , 4As shown, the columnar body 3-1 and the mesh body 3-2 are an integral structure. The mesh body 3-2 has evenly distributed permeable mesh openings on its plane. The columnar body 3-1 is located at one end of the mesh sample holder. The outer diameter of the columnar body 3-1 matches the inner diameter of the inner hole 2-1 of the tube cap 2. The mesh sample holder 3 is tightly connected to the inner hole of the tube cap 2 via the columnar body 3-1. The specimen tissue is placed on the mesh surface of the mesh body 3-2. The length and width of the mesh sample holder 3 match the depth and inner diameter of the cryopreservation tube. In this embodiment, the depth of the cryopreservation tube is 75 mm, the inner diameter is 10 mm, the total length of the mesh sample holder 3 is 70 mm, the width of the mesh body 3-2 is 8 mm, and the widest part of the mesh opening is 1 mm. The outer surface of the tube is marked with a capacity scale 1-1 to facilitate the user's control of the addition of cryosol; the outer surface of the tube is also marked with a sample identification recording area 1-2 to mark the number of the sample tissue in the cryopreservation tube.

[0012] In this embodiment, the mesh sample holder 3 is made of titanium alloy, which can avoid damage to the specimen tissue. The mesh of the mesh sample holder 3 has a planar structure, allowing for free selection of the specimen tissue placement position.

[0013] The scope of protection of this utility model is not limited to the above embodiments. Any cryopreservation tube that is the same as or equivalent to the technical solution and structure of this utility model, as well as cryopreservation tube that is the same as the technical solution of this utility model in principle, shall fall within the scope of protection of this utility model.

Claims

1. A cryopreservation tube with a mesh sample holder, comprising a tube body and a cap, wherein the upper inner side of the tube body is provided with an internal thread, the lower end of the cap is provided with an external thread, the tube body and the cap are connected by screwing on the threads, and a sealing rubber ring is installed at the interface between the tube body and the cap, characterized in that... The lower part of the tube cap has a cylindrical inner hole, in which a mesh sample holder is connected. The mesh sample holder is composed of columnar bodies and mesh bodies, which are integrated into one structure. The mesh body has evenly distributed permeable mesh holes on its plane. The columnar bodies are located at one end of the mesh sample holder, and the outer diameter of the columnar bodies matches the inner diameter of the inner hole at the lower part of the tube cap. The mesh sample holder is tightly connected to the inner hole of the tube cap through the columnar bodies, and the specimen tissue is placed on the mesh surface.

2. A cryopreservation tube with a mesh sample holder according to claim 1, characterized in that... The length and width of the mesh sample holder are matched with the depth and inner diameter of the cryopreservation tube, and the widest part of the mesh on the mesh body is less than or equal to 1 mm.

3. A cryopreservation tube with a mesh sample holder according to claim 1 or 2, characterized in that... The outer surface of the tube is marked with capacity scale.

4. A cryopreservation tube with a mesh sample holder according to claim 1 or 2, characterized in that... The outer surface of the tube is also provided with a sample identification and recording area.

5. A cryopreservation tube with a mesh sample holder according to claim 1 or 2, characterized in that... The mesh sample holder is made of titanium alloy.