Medicament proportioning and dosing device

Abstract

The utility model relates to technical field of medicament production equipment provides a kind of medicament proportioning and adding device, it include: raw drug module, for providing raw drug;Diluent module, for providing diluent;Mixer, the outlet of raw drug module and diluent module is connected with the inlet of mixer, for mixing raw drug and diluent;Adding module, inlet is connected with the outlet of mixer, for putting mixed medicament;Circulation pipe, one end is connected with the outlet of mixer, another end is connected to the inlet of mixer;Control valve, it is connected in the outlet of mixer, for controlling the outlet of mixer and the selective conduction of adding module and circulation pipe.Such setting, can prolong the residence time of medicament in mixer, effectively break the cluster formed by high viscosity medicament, reduce the mixing problem of traditional static mixer due to the viscosity of medicament is larger or flow fluctuation, significantly improve the uniformity of medicament mixing, to ensure the accuracy of medicament concentration and use effect.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical production equipment technology, and in particular to a pharmaceutical formulation and dosing device. Background Technology

[0002] In numerous fields such as chemical engineering, pharmaceuticals, environmental protection, and agriculture, the dilution and precise proportioning of reagents are crucial for ensuring the stability of production processes, the reliability of product quality, and the effectiveness of operational results. Whether it is chemical reagents used in industrial production, pesticides used for pest and disease control in agricultural planting, or medicinal solutions used for treatment in the medical field, they often need to be diluted and mixed with solvents (such as water, organic solvents, etc.) in specific proportions to achieve the optimal concentration and effect.

[0003] The dilution and proportioning process of pharmaceuticals typically involves core steps such as metering, conveying, and mixing. Static mixers, as a commonly used traditional mixing device, are widely used in pharmaceutical mixing scenarios due to their lack of moving parts and compact structure. Their working principle involves using mixing units (such as spiral vanes or corrugated plates) fixed within the pipeline to force the fluid to undergo splitting, displacement, and recombination during flow, thereby achieving mixing of the pharmaceuticals and solvents. This mixing method eliminates the need for external power to drive the stirring components, reducing equipment maintenance costs to some extent and adapting to the needs of continuous production.

[0004] However, static mixers still have certain limitations. For example, for agents and solvents with large viscosity differences, the flow velocity distribution within the static mixer is prone to deviation. High-viscosity components may accumulate in the center or on the walls of the pipe due to high flow resistance, resulting in insufficient mixing. Furthermore, when the throughput fluctuates, the mixing effect of the static mixer will significantly decrease. When the flow rate is too high, the residence time of the fluid in the mixing unit is insufficient, making it difficult to achieve thorough mixing; when the flow rate is too low, insufficient shear force may fail to break up agent clusters. Uneven mixing will adversely affect the consistency of agent concentration and its effectiveness.

[0005] In view of the above problems, how to improve the mixing effect and ensure the accuracy of the drug concentration and the effect of use has become an important issue that urgently needs to be addressed. Utility Model Content

[0006] This invention provides a drug mixing and dosing device to solve the defect of uneven mixing of highly viscous drugs in the prior art, which can improve the uniformity of drug mixing, thereby ensuring the accuracy of drug concentration and the effect of use.

[0007] This utility model provides a drug mixing and dosing device, including: The active ingredient module is used to provide the active ingredient; The dilution module is used to provide the diluent; The mixer has outlets for both the drug substance module and the dilution module connected to the inlet of the mixer for mixing the drug substance and the diluent. The dosing module has an inlet connected to the outlet of the mixer and is used to dispense the mixed reagent. A circulation pipe is connected at one end to the outlet of the mixer and at the other end to the inlet of the mixer; A control valve is connected to the outlet of the mixer, one end of the circulation pipe, and the inlet of the dosing module, and is used to control the selective conduction of the outlet of the mixer with the dosing module and the circulation pipe.

[0008] According to the pharmaceutical preparation and dosing device provided by this utility model, the active pharmaceutical ingredient module includes: The raw material compartment is used to hold the raw material. A raw material pump is located between the raw material chamber and the mixer, and is used to output a preset metered amount of raw material.

[0009] According to the pharmaceutical preparation and dosing device provided by this utility model, the original drug chamber includes an outer shell and a PTFE inner liner disposed within the outer shell; and / or, The original drug cavity is equipped with a wall-scraping spiral device.

[0010] According to the pharmaceutical preparation and dosing device provided by this utility model, the dilution module includes: A dilution chamber, used to hold diluent; A dilution pump, located between the dilution chamber and the mixer, is used to output a preset metered amount of diluent.

[0011] According to the present invention, a drug preparation and dosing device is provided, wherein the dosing module includes: The dosing chamber is used to hold the mixed medicine. A corrosion-resistant discharge valve is connected to the outlet of the feeding chamber.

[0012] According to the pharmaceutical preparation and dosing device provided by this utility model, the control valve includes a three-way valve; The inlet of the three-way valve is connected to the outlet of the mixer, one outlet is connected to the circulation pipe, and the other outlet is connected to the inlet of the dosing module.

[0013] The pharmaceutical preparation and dosing device provided by this utility model also includes a controller; The controller is signal-connected to the drug substance module and the dilution module. The drug substance module and the dilution module are controlled by the controller to provide drug substance and diluent at a set dilution ratio.

[0014] According to the present invention, a drug preparation and dosing device is provided, wherein the dosing module is equipped with a level gauge for monitoring the liquid level of the drug.

[0015] According to the pharmaceutical mixing and dosing device provided by this utility model, the level gauge is signal-connected to the controller; When the liquid level of the drug in the dosing module is lower than a preset value, the controller generates and sends a shutdown command, and the original drug module, the dilution module and the dosing module shut down based on the shutdown command.

[0016] The drug mixing and dosing device provided by this utility model also includes a human-machine interaction module that is signal-connected to the controller. The human-computer interaction module is equipped with control buttons for inputting control commands.

[0017] The drug mixing and dosing device provided by this utility model also includes an alarm module, which alarms based on the shutdown command.

[0018] According to the pharmaceutical preparation and dosing device provided by this utility model, the original drug pump includes a corrosion-resistant plunger pump.

[0019] According to the drug formulation and dosing device provided by this utility model, the bottom surface of the inner liner of the original drug cavity is set as a conical surface.

[0020] The drug mixing and dosing device provided by this utility model includes a raw material module that provides the raw material and a dilution module that provides the diluent. The raw material and diluent in a specific ratio enter the mixer for mixing, and the mixed drug then enters the dosing module for addition. A control valve can selectively connect the mixer outlet to either the dosing module or the circulation pipeline, thereby switching between two modes: "circulation back to the mixer" or "direct dosing." For example, when the drug viscosity is low and mixing is easy, the control valve can connect the mixer outlet to the dosing module, allowing the drug to be directly added to the dosing module after mixing, ensuring efficient drug dilution. When the drug viscosity is high and mixing is difficult, the control valve can connect the mixer outlet to the circulation pipeline, allowing the drug to return to the mixer via the circulation pipeline for further mixing.

[0021] Compared to related technologies, this method can extend the residence time of the agent in the mixer, effectively break up the clusters formed by high-viscosity agents, reduce the problem of insufficient mixing caused by high agent viscosity or flow fluctuations in traditional static mixers, and significantly improve the uniformity of agent mixing, thereby ensuring the accuracy of agent concentration and the effect of use.

[0022] In addition, during the cleaning stage, the original drug module can be shut down and the dilution module can be turned on. The control valve can be used to control the connection between the mixer outlet and the circulation pipe. The diluent circulates through the circulation pipe to clean the mixer. In this way, the original drug residue can be effectively removed, and problems such as cross-contamination between different batches of drugs, residual crystals clogging the pipeline or interfering with the subsequent mixing concentration can be reduced, thus ensuring the continuous and stable operation of the device. Attached Figure Description

[0023] To more clearly illustrate the technical solutions in this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0024] Figure 1 This is a schematic diagram of the drug formulation and dosing device provided in this embodiment of the utility model.

[0025] Figure label: 10. Raw material module; 101. Raw material chamber; 102. Raw material pump; 11. Scraping spiral device; 12. First pipeline; 20. Dilution module; 201. Dilution chamber; 21. Second pipeline; 30. Mixer; 301. Outer casing; 302. Kenics spiral element; 31. Main input pipeline; 32. Main output pipeline; 40. Dosing module; 401. Dosing chamber; 41. Third pipeline; 42. Level gauge; 50. Circulation pipe; 60. Control valve. Detailed Implementation

[0026] To make the objectives, technical solutions, and advantages of this utility model clearer, the technical solutions of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this utility model, not all embodiments. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0027] To better understand the reagent proportioning and dosing device provided in this embodiment, its application background is first introduced. In many fields such as chemical, pharmaceutical, environmental protection, and agriculture, the dilution and precise proportioning of reagents are crucial to the stability of production processes, the reliability of product quality, and the effectiveness of operations. Reagent proportioning typically involves core steps such as metering, conveying, and mixing. Static mixers, as a common traditional mixing device, are widely used in reagent mixing scenarios due to their characteristics of having no moving parts and a compact structure.

[0028] However, static mixers still have certain limitations. For example, for agents and solvents with large viscosity differences, the flow velocity distribution within the static mixer is prone to deviation. High-viscosity components may accumulate in the center or on the walls of the pipe due to high flow resistance, resulting in insufficient mixing. Furthermore, when the throughput fluctuates, the mixing effect of the static mixer will significantly decrease. When the flow rate is too high, the residence time of the fluid in the mixing unit is insufficient, making it difficult to achieve thorough mixing; when the flow rate is too low, insufficient shear force may fail to break up agent clusters. Uneven mixing will adversely affect the accuracy of agent concentration and its effectiveness.

[0029] In view of the above problems, this utility model provides a drug mixing and dosing device, which can improve the uniformity of drug mixing, thereby ensuring the accuracy of drug concentration and the effectiveness of use. The drug selected in this utility model embodiment is a corrosive and highly viscous nano-flocculator.

[0030] The following is combined with Figure 1 This invention describes the drug formulation and dosing device.

[0031] Reference Figure 1 A drug preparation and dosing device includes a raw material module 10, a dilution module 20, a mixer 30, a dosing module 40, a circulation pipe 50, and a control valve 60. The raw material module 10 provides the raw material; the dilution module 20 provides the diluent; the inlet of the mixer 30 is connected to the outlets of the raw material module 10 and the dilution module 20 for mixing the raw material and the diluent; the inlet of the dosing module 40 is connected to the outlet of the mixer 30 for dispensing the mixed drug; one end of the circulation pipe 50 is connected to the outlet of the mixer 30, and the other end is connected to the inlet of the mixer 30; the control valve 60 is connected to the outlet of the mixer 30 for selectively controlling the connection between the outlet of the mixer 30 and either the dosing module 40 or the circulation pipe 50.

[0032] In practical applications, the active pharmaceutical ingredient module 10 provides the active pharmaceutical ingredient, and the dilution module 20 provides the diluent. A specific ratio of active pharmaceutical ingredient and diluent enters the mixer 30 for mixing, and the resulting mixture enters the dosing module 40 for dosing. The control valve 60 can control the connection between the outlet of the mixer 30 and either the dosing module 40 or the circulation pipe 50, thereby enabling switching between "circulation back to the mixer 30" or "direct dosing" modes.

[0033] For example, when the viscosity of the agent is low and mixing is relatively easy, the outlet of the mixer 30 can be connected to the dosing module 40 by the control valve 60. After being mixed by the mixer 30, the agent directly enters the dosing module 40 for dosing, ensuring the agent dilution efficiency. When the viscosity of the agent is high and mixing is relatively difficult, the outlet of the mixer 30 can be connected to the circulation pipe 50 by the control valve 60. After passing through the mixer 30, the agent returns to the mixer 30 through the circulation pipe 50 to continue mixing.

[0034] Compared to related technologies, this method can extend the residence time of the agent in the mixer 30, effectively break up the clusters formed by high-viscosity agents, reduce the problem of insufficient mixing caused by high agent viscosity or flow fluctuations in traditional static mixers 30, significantly improve the uniformity of agent mixing, and thus ensure the accuracy of agent concentration and the effect of use.

[0035] In addition, during the cleaning stage, the original drug module 10 can be shut down and the dilution module 20 can be turned on. The control valve 60 can be used to control the outlet of the mixer 30 to be connected to the circulation pipe 50. The diluent circulates through the circulation pipe 50 to clean the mixer 30. In this way, the original drug residue can be effectively removed, and problems such as cross-contamination between different batches of drugs, residual crystals clogging the pipeline or interfering with the subsequent mixing concentration can be reduced, thus ensuring the continuous and stable operation of the device.

[0036] In one example of this invention, the active pharmaceutical ingredient module 10 includes an active pharmaceutical ingredient chamber 101 and an active pharmaceutical ingredient pump 102. The active pharmaceutical ingredient chamber 101 holds the active pharmaceutical ingredient. The active pharmaceutical ingredient pump 102 is positioned between the active pharmaceutical ingredient chamber 101 and the mixer 30, and is used to output a preset metered amount of active pharmaceutical ingredient. With this configuration, the active pharmaceutical ingredient chamber 101, as a storage carrier for the active pharmaceutical ingredient, can stably hold a sufficient amount of active pharmaceutical ingredient, avoiding interruptions in the delivery process due to frequent material additions and ensuring the continuity of the drug formulation. Meanwhile, the active pharmaceutical ingredient pump 102 can output a preset metered amount of active pharmaceutical ingredient, ensuring the accuracy of the drug formulation.

[0037] In detail, the raw material chamber 101 includes an outer shell and a PTFE (Polytetrafluoroethylene) inner liner disposed within the outer shell. The raw material is placed in the inner liner. The PTFE material inner liner has excellent corrosion resistance and anti-adhesion properties, which can effectively prevent corrosion and adhesion of the raw material, and significantly improve the safety and stability of raw material storage.

[0038] The bottom surface of the inner liner is set as a cone. The cone structure has natural guiding properties. As the amount of raw drug in the raw drug cavity 101 gradually decreases, the remaining drug will converge towards the lowest point of the bottom surface along the slope of the cone under the action of gravity. Even raw drugs with high viscosity (such as paste drugs and suspensions) can flow towards the outlet under the guidance of the cone, thereby reducing raw drug residue and achieving complete emptying of raw drug.

[0039] For some high-viscosity, easily crystallizing, or fine-particle-containing active ingredients, even with PTFE's excellent anti-adhesion properties, it is still difficult to avoid the problem of the active ingredient sticking to the wall, resulting in the inability to completely remove the active ingredient.

[0040] Therefore, in a further example of this utility model, a wall-scraping spiral device 11 is provided in the inner liner. Specifically, an electric wall-scraping spiral device can be used. With this configuration, during the rotation of the wall-scraping spiral device 11, its spiral blades can continuously scrape along the inner wall of the inner liner, effectively removing the original drug adhering to the surface of the PTFE inner liner and ensuring the complete removal of the original drug to the greatest extent possible.

[0041] It should be noted that the specific structure of the wall-scraping spiral device 11 can refer to the prior art, and will not be described in detail in this embodiment. The model, size, and other parameters of the wall-scraping spiral device 11 need to be adapted to the actual needs and inner liner specifications, and will not be specifically limited in this embodiment.

[0042] In one example of this utility model, the active pharmaceutical ingredient pump 102 serves as a quantitative delivery element for the active pharmaceutical ingredient. It may include various types of metering pumps, which can be selected according to the characteristics of the active pharmaceutical ingredient (such as viscosity, corrosiveness, solid content, etc.) and the delivery accuracy requirements to ensure the accuracy and stability of the delivery of the active pharmaceutical ingredient.

[0043] In this embodiment, the active pharmaceutical ingredient pump 102 includes a corrosion-resistant plunger pump, which includes, but is not limited to, ceramic plunger pumps, corrosion-resistant lined (e.g., PTFE) plunger pumps, etc. The pump body and fluid contact parts are made of corrosion-resistant materials such as zirconia ceramics or PTFE, so that the active pharmaceutical ingredient pump 102 has excellent corrosion resistance and ensures the accuracy and stability of active pharmaceutical ingredient metering and delivery.

[0044] It should be noted that the corrosion-resistant plunger pump is a mature existing product, and its specific structure and working principle can be referenced from existing technologies, so they will not be elaborated upon in this embodiment. The specifications of the corrosion-resistant plunger pump can be configured according to actual needs, and no specific limitations are imposed in this embodiment.

[0045] In one example of this invention, the raw material chamber 101 is connected to the inlet of the mixer 30 via a first pipeline 12, and the raw material pump 102 is connected to the first pipeline 12 for metering and pumping the raw material. The dilution module 20 is connected to the inlet of the mixer 30 via a second pipeline 21.

[0046] It is understandable that the first pipeline 12 and the second pipeline 21 can be connected to the inlet of the mixer 30 as two separate pipelines for independent control. Alternatively, they can merge into a single main inlet pipeline 31 before entering the mixer 30. This initial merging and flow within the main inlet pipeline 31 allows the active ingredient and diluent to be premixed before entering the mixer 30, increasing their contact time and area. The single-pipe connection after merging simplifies the structural design of the mixer 30 inlet, reduces the number of interfaces, lowers the complexity of pipeline connections and the risk of leakage, and saves installation space, resulting in a more compact overall layout. The two pipeline layout methods described above can be selected according to actual needs.

[0047] As a specific example of this utility model, the first pipeline 12 and the second pipeline 21 merge into a total input pipeline 31 before entering the mixer 30.

[0048] In one example of this utility model, the dilution module 20 includes a dilution chamber 201 and a dilution pump; wherein, the dilution chamber 201 is used to hold the diluent; the dilution pump is disposed between the dilution chamber 201 and the mixer 30, and is used to meter and pump the diluent.

[0049] In detail, the dilution chamber 201 is made of 304 stainless steel, giving it excellent structural strength and corrosion resistance. Various types of metering pumps can be used for the dilution pump, such as plunger metering pumps and diaphragm metering pumps, to ensure the accuracy and stability of the diluent delivery.

[0050] Through the above technical solution, the original drug provided by the original drug module 10 and the diluent provided by the dilution module 20 can be mixed in a specific ratio in the mixer 30 to obtain a drug dilution solution.

[0051] In one example of this invention, the mixer 30 is a static mixer, comprising a 316L stainless steel housing 301 and a Kenics spiral element 302 detachably connected within the housing 301. With this configuration, the Kenics spiral element 302, as a highly efficient static mixing unit, can achieve thorough mixing solely through fluid flow without external power. The detachable connection between the housing 301 and the Kenics spiral element 302 allows for easy disassembly and thorough cleaning, preventing contamination of newly prepared materials by residual agents. For different mixing requirements, the shear strength and mixing efficiency of the mixer 30 can be quickly adjusted by replacing the Kenics spiral element 302 with different parameters (such as blade pitch, torsion angle, and element length) without replacing the entire mixer 30 housing, significantly reducing equipment adaptation costs.

[0052] It should be clarified here that the static mixer 30 and its internal Kenics spiral element 302 are mature products, and their structure and working principle are within the scope of common technical knowledge mastered by those skilled in the art. Therefore, they will not be described in detail in this embodiment of the utility model.

[0053] In one example of this utility model, the outlet of the mixer 30 is connected to the dosing module 40 through the third pipeline 41 and to the inlet of the mixer 30 through the circulation pipe 50. The control valve 60 controls the outlet of the mixer 30 to selectively connect with either the dosing module 40 or the circulation pipe 50, thereby realizing the switching between the two modes of "circulating back to the mixer 30" or "direct dosing".

[0054] In detail, the circulation pipe 50 and the third pipe 41 can be two completely independent pipes connected to the inlet of the mixer 30 respectively, or a total output pipe 32 can be connected to the outlet of the mixer 30, and then connected to the circulation pipe 50 and the third pipe 41 respectively using a tee structure to simplify the pipe layout.

[0055] In this embodiment, the outlet of the mixer 30 is connected to a main output pipeline 32, the circulation pipeline 50 and the third pipeline 41 are respectively connected to the main output pipeline 32, and the circulation pipeline 50 is connected to the inlet of the mixer 30 by connecting to the main pipeline.

[0056] The control valve 60 serves as a component for switching between the "circulation back to mixer 30" and "direct addition" modes, and its specific structural form can be selected according to actual needs.

[0057] In one feasible example, the control valve 60 may include two valves, one of which is connected to the circulation pipe 50 to control the opening and closing of the circulation pipe 50, and the other valve is connected to the third pipe 41 to control the opening and closing of the third pipe 41. Through the cooperation of the two valves, the switching between the two modes of "circulation back to mixer 30" or "direct addition" can be realized.

[0058] In another example of this utility model, the control valve 60 is a three-way valve; the inlet of the three-way valve is connected to the outlet of the mixer 30, one outlet is connected to the circulation pipe 50, and the other outlet is connected to the inlet of the dosing module 40. With this configuration, the three-way valve can quickly switch between the two modes of "circulation back to mixer 30" and "direct dosing" through a single valve body switching action, which simplifies the structure and improves the convenience of control.

[0059] In detail, a three-way valve can be a three-way ball valve. In addition, to improve corrosion resistance, a PTFE ball valve can be used for a three-way valve.

[0060] In one example of this utility model, the dosing module 40 includes a dosing chamber 401 and a corrosion-resistant discharge valve; wherein, the dosing chamber 401 is used to hold the mixed agent; the corrosion-resistant discharge valve is connected to the outlet of the dosing chamber 401 and is used to output the agent.

[0061] In detail, the corrosion-resistant discharge valve adopts a PTFE electromagnetic diaphragm valve, which can accept 4-20mA signals to remotely adjust the opening.

[0062] In a further example of this utility model, a level gauge 42 is provided on the dosing chamber 401 to facilitate monitoring of the drug dosage in the dosing chamber 401.

[0063] For ease of control, in one example of this utility model, the drug mixing and dosing device also includes a controller; the raw material module 10 and the dilution module 20 are controlled by the controller and are used to provide the raw material and diluent with a set dilution ratio.

[0064] In detail, the controller can be an existing PLC (Programmable Logic Controller). The controller can preset or receive externally input dilution ratio parameters (such as 1:50, 1:1000, etc.) and automatically calculate the theoretical delivery volume of the active ingredient and diluent based on these parameters. An electrical signal connection is established with the active ingredient pump 102 (such as a corrosion-resistant plunger pump) of the active ingredient module 10 and the delivery device (such as a metering pump) of the dilution module 20. The operating parameters of the equipment are dynamically adjusted using PID (proportional-integral-derivative) control algorithms to ensure that the active ingredient and diluent are delivered in a coordinated manner according to the preset ratio, thus ensuring the accuracy of the mixing ratio.

[0065] In a further example of this utility model, the level gauge 42 is connected to the controller signal; when the liquid level in the dosing chamber 401 is lower than a preset value (e.g., 10%), the controller generates and sends a shutdown command, and the original drug module 10, the dilution module 20 and the dosing module 40 shut down based on the shutdown command.

[0066] In a further embodiment of this utility model, the reagent mixing and dosing device also includes an alarm module. The alarm module alarms based on the shutdown command, including but not limited to audible and visual alarms (such as buzzers and warning lights) or information push (such as SMS messages and pop-ups in the central control system). In this way, operators can quickly know the shutdown status of the device, significantly shorten the fault response time, and reduce the production losses caused by shutdown.

[0067] In a further example of this utility model, the drug mixing and dosing device also includes a human-machine interaction module connected to the controller signal; the human-machine interaction module is provided with control buttons for inputting control commands.

[0068] In detail, the human-computer interaction module can use a touch screen; control buttons include, but are not limited to, power control buttons, operation control buttons, parameter setting buttons, and function shortcut keys.

[0069] For example, the operation control buttons include a one-button flushing button. When the cleaning program is executed, the original drug pump 102 is turned off, the dilution pump is turned on, and the mixer 30 is circulated for 2 minutes and then emptied.

[0070] It is understood that, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of the different embodiments or examples.

[0071] The drug mixing and dosing device provided by this utility model can effectively break up the clusters formed by high-viscosity drugs, extend the residence time of the drugs in the mixer 30, reduce the problem of insufficient mixing caused by high drug viscosity or flow fluctuation in the traditional static mixer 30, significantly improve the uniformity of drug mixing, and thus ensure the accuracy of drug concentration and the effect of use.

[0072] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this utility model, and not to limit it. Although this utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of this utility model.

Claims

1. A pharmaceutical preparation and dosing device, characterized in that, include: The active ingredient module (10) is used to provide the active ingredient; A dilution module (20) is used to provide diluent; The mixer (30) has outlets for both the drug substance module (10) and the dilution module (20) connected to the inlet of the mixer (30) for mixing the drug substance and the diluent. The dosing module (40) has its inlet connected to the outlet of the mixer (30) and is used to dispense the mixed reagent; A circulation pipe (50) is connected at one end to the outlet of the mixer (30) and at the other end to the inlet of the mixer (30); A control valve (60) is connected to the outlet of the mixer (30), one end of the circulation pipe (50), and the inlet of the dosing module (40) to control the selective connection between the outlet of the mixer (30) and the dosing module (40) and the circulation pipe (50).

2. The reagent proportioning and dosing device according to claim 1, characterized in that, The active ingredient module (10) includes: The raw material cavity (101) is used to hold the raw material; A raw material pump (102) is disposed between the raw material chamber (101) and the mixer (30) for outputting a preset amount of raw material.

3. The medicament dispensing and dosing device according to claim 2, characterized in that The original drug cavity (101) includes an outer shell and a PTFE inner liner disposed within the outer shell; and / or, The original drug cavity (101) is equipped with a wall scraping spiral device (11).

4. The medicament mixing and administering device according to claim 2, wherein The original drug pump (102) includes a corrosion-resistant plunger pump.

5. The reagent proportioning and dosing device according to claim 1, characterized in that, The dilution module (20) includes: The dilution chamber (201) is used to hold the diluent; A dilution pump is disposed between the dilution chamber (201) and the mixer (30) for outputting a preset metered amount of diluent.

6. The medicament compounding and administering device according to claim 1, wherein The dosing module (40) includes: The dosing chamber (401) is used to hold the mixed medicine; A corrosion-resistant discharge valve is connected to the outlet of the feeding chamber (401).

7. The medicine dispensing and dosing device according to any one of claims 1 to 6, characterized in that It also includes the controller; The controller is signal-connected to the drug module (10) and the dilution module (20). The drug module (10) and the dilution module (20) are controlled by the controller to provide drug and diluent at a set dilution ratio.

8. The pharmaceutical preparation and dosing device according to claim 7, characterized in that, The dosing module (40) is equipped with a level gauge (42) for monitoring the liquid level of the agent.

9. The pharmaceutical preparation and dosing device according to claim 8, characterized in that, The level gauge (42) is signal-connected to the controller; When the liquid level of the drug in the dosing module (40) is lower than the preset value, the controller generates and sends a shutdown command, and the original drug module (10), the dilution module (20) and the dosing module (40) shut down based on the shutdown command.

10. The pharmaceutical preparation and dosing device according to claim 9, characterized in that, It also includes a human-machine interface module that is signal-connected to the controller; the human-machine interface module is provided with control buttons for inputting control commands; and / or, It also includes an alarm module, which issues an alarm based on the shutdown command.

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