SYSTEM FOR IDENTIFYING AND MANAGING CORTIC STIMULATION SITE FOR THE APPLICATION OF A FOCAL NEUROMODULATION PROCEDURE

DE602016094010T2Active Publication Date: 2025-11-05NEUROCARE GRP NETHERLANDS BV
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Patent Information

Application Number
DE602016094010
Authority / Receiving Office
DE · DE
Patent Type
Patents
Current Assignee / Owner
Filing Date
2016-12-09
Publication Date
2025-11-05
Estimated Expiration
2036-12-09

AI Technical Summary

Technical Problem

Existing methods for targeting cortical areas for neuromodulation techniques, such as TMS, are often inaccurate and rely on anatomical assumptions, failing to account for functional connectivity to deeper brain regions like the ventromedial prefrontal cortex, which may limit therapeutic efficacy.

Method used

A method and system using transcranial magnetic stimulation (TMS) to identify cortical stimulation sites by measuring psychophysiological signals, particularly heart rate changes, to optimize targeting of the ventromedial prefrontal cortex, including the subgenual and rostral anterior cingulate, through trans-synaptic connectivity.

Benefits of technology

Precisely identifies functional cortical areas for neuromodulation, enhancing therapeutic efficacy by directly targeting the ventromedial prefrontal cortex, which is otherwise inaccessible due to its depth, and allowing real-time verification of stimulation accuracy.

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