Wound protection sheet, and method of manufacturing wound protection sheet

Abstract

To provide a wound protection sheet, the interlayer of which is less peelable than ever, and a method of manufacturing the wound protection sheet.SOLUTION: A wound protection sheet capable of being used to protect a wound site after surgery such as an incision comprises: a first adhesive rubber layer having adhesiveness; a second adhesive rubber layer lower in adhesiveness than the first adhesive rubber layer; and an adhesion layer. The adhesion layer is arranged between the first and second adhesive rubber layers. The first and second adhesive rubber layers are bonded together via the adhesion layer.SELECTED DRAWING: Figure 1

Description

[Technical field]

[0001] The present invention relates to a wound protection sheet and a method for producing the wound protection sheet. [Background technology]

[0002] Conventionally, wound protection sheets have been used to protect the site of a wound after surgery such as incision (for example, Patent Document 1). Conventional wound protection sheets have a two-layer structure, with a rubber layer with low adhesiveness and a rubber layer with high adhesiveness, and these two layers are directly attached to each other. By using the less adhesive layer on the clothing side and the more adhesive layer on the skin side, the wound protection sheet can adhere to the skin so as to cover the wound site and protect it. In addition, since the wound protection sheet does not easily stick to the clothing worn, it can be prevented from the wound protection sheet sticking to clothing in daily life and peeling off from the wound site, making it impossible to protect the wound site. [Prior art documents] [Patent documents]

[0003] [Patent Document 1] Japanese Patent Application Publication No. 1-34370 Summary of the Invention [Problem to be solved by the invention]

[0004] Wound protection sheets may be used repeatedly, for example by washing or disinfecting with alcohol. During repeated use, the two adhering layers may come off, for example when removing the wound protection sheet from the skin. If the two adhering layers come off, the wound protection sheet loses its function and cannot be used.

[0005] Furthermore, the wound protection sheet is manufactured so that the two layers (the less adhesive rubber layer and the more adhesive rubber layer) are tightly adhered to each other so that they do not easily peel off at the interface. The two tightly adhered layers can be manufactured by molding the more adhesive rubber before the less adhesive rubber hardens (while it is in a gel state). However, this requires that the more adhesive rubber be molded within a time limit before the less adhesive rubber hardens.

[0006] The present invention has been made in consideration of the above circumstances, and has as its object to provide a wound protection sheet which is more resistant to peeling, in which a rubber layer with low adhesiveness and a rubber layer with high adhesiveness are bonded together. Also provided is a method for manufacturing a wound protection sheet that enables molding of highly adhesive rubber without being affected by the cured state of less adhesive rubber, thereby eliminating the time constraint of molding the highly adhesive rubber before the less adhesive rubber cures. [Means for solving the problem]

[0007] In order to solve the above problems, the present invention has the following aspects. [1] A wound protection sheet comprising a first adhesive rubber layer having adhesion to skin, a second adhesive rubber layer having less adhesion to skin than the first adhesive rubber layer, and an adhesive layer, wherein the adhesive layer is disposed between the first adhesive rubber layer and the second adhesive rubber layer, and the first adhesive rubber layer and the second adhesive rubber layer are adhered to each other via the adhesive layer. [2] The wound protection sheet described in [1], wherein the first adhesive rubber layer and the second adhesive rubber layer are cured products of condensation-type silicone rubber that hardens at room temperature. [3] A method for producing a wound protection sheet as described in [1] or [2], comprising a step of providing the adhesive layer and the first adhesive rubber layer before curing on the second adhesive rubber layer, and the second adhesive rubber layer may be in a pre-cured state or a cured state. [4] The method for manufacturing a wound protection sheet described in [3], wherein the material of the first adhesive rubber layer and the second adhesive rubber layer is a condensation type silicone rubber that hardens at room temperature. Effect of the Invention

[0008] According to the present invention, it is possible to provide a wound protection sheet in which a rubber layer with low adhesion (first adhesive rubber layer) and a rubber layer with high adhesion (second adhesive rubber layer) are bonded via an adhesive layer, and these two adhesive rubber layers are less likely to peel off from each other. It is also possible to provide a method for producing a wound protection sheet that can eliminate the time restriction that the second adhesive rubber layer to be laminated on the first adhesive rubber layer must be formed before the first adhesive rubber layer hardens. [Brief description of the drawings]

[0009] [Figure 1] 1 is a cross-sectional view showing a schematic diagram of a first embodiment of a wound protection sheet of the present invention. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0010] Hereinafter, a detailed description will be given with reference to the drawings, but the dimensions of the drawings are different from the actual dimensions for the convenience of explanation. Also, the present invention is not limited to the embodiments.

[0011] [Wound protection sheet] A first aspect of the present invention is a wound protection sheet. As shown in Fig. 1, the wound protection sheet 1, which is an example of an embodiment according to this aspect, is a wound protection sheet 1 comprising a first adhesive rubber layer 2 (hereinafter referred to as adhesive rubber layer 2), a second adhesive rubber layer 3 (hereinafter referred to as non-adhesive rubber layer 3) having less adhesiveness than the adhesive rubber layer 2, and an adhesive layer 4. The adhesive layer 4 is disposed between the adhesive rubber layer 2 and the non-adhesive rubber layer 3. In other words, the wound protection sheet 1 is a laminate having a three-layer structure.

[0012] The wound protection sheet 1 is a sheet that covers damage to internal tissues or skin, such as wounds caused by incisions, ulcers, burns, etc., to protect the affected area until the tissue or skin regenerates or heals, and in some cases promotes regeneration or healing.

[0013] The size of the wound protection sheet 1 can be appropriately selected depending on the affected area, for example, a diameter of 5 cm or more and 20 cm or less.

[0014] The thickness of the wound protective sheet 1 is not particularly limited, but may be, for example, from 200 μm to 50,000 μm, and preferably from 200 μm to 6,000 μm.

[0015] The shape of the wound protection sheet 1 is not particularly limited, but from the viewpoint of using the sheet by adhering it to the skin so as to cover the affected area, it is preferably thin, for example, a thin oval shape. Furthermore, the wound protection sheet 1 can be cut with scissors or the like according to the size of the affected area when used, and the wound protection sheet 1 can be used by appropriately selecting the desired size and shape.

[0016] In order for the wound protection sheet 1 to cover and protect the affected area, it is preferable that the wound protection sheet 1 itself can be used by adhering to the skin. That is, it is preferable that one surface of the three-layered wound protection sheet 1, the adhesive rubber layer 2, has adhesiveness. If one surface of the wound protection sheet 1 has adhesiveness, it can be used by adhering to the skin, and it is easy to carry, as it can be used while being attached to the skin and can be used in daily life. The surface of the non-adhesive rubber layer 3, which is the other surface of the wound protection sheet 1 (the surface opposite to the surface to be attached to the skin), is preferably not adhesive enough to be used by attaching it to the skin. In other words, it is preferable that one of the surfaces of the wound protection sheet 1 having a three-layer structure is not very adhesive. If one surface of the wound protection sheet 1 is not adhesive enough to be used by attaching it to the skin, the wound protection sheet 1 attached to the affected area can be prevented from sticking to places other than the intended location, such as clothing being worn.

[0017] The adhesive rubber layer 2 is a layer that forms one side of the surface of the wound protection sheet 1 which has a three-layer structure. The adhesive rubber layer 2 includes an adhesive resin and may further include a water-repellent component. The adhesive resin is preferably a rubber-based adhesive, but is not limited thereto and may be, for example, an acrylic adhesive. The adhesive rubber layer 2 is formed by hardening the adhesive resin.

[0018] Examples of rubber-based adhesives include RTV rubber (Room Temperature Vulcanizing), synthetic polyisoprene rubber, styrene butadiene rubber, etc. From the viewpoint of bonding the adhesive rubber layer 2 and the adhesive rubber layer 3 more reliably, RTV rubber is preferred. Here, RTV rubber refers to a highly viscous paste or liquid rubber (silicone rubber) that contains silicone and quickly cures in a room temperature environment to become a cured silicone rubber. That is, the RTV rubber is a condensation type, a room temperature curing type silicone RTV rubber that cures at room temperature.

[0019] Examples of acrylic pressure-sensitive adhesives include homopolymers of (meth)acrylic acid alkyl ester monomers such as butyl acrylate, 2-ethylhexyl acrylate, isononyl acrylate, etc., or copolymers of these monomers, as well as pressure-sensitive adhesives containing copolymers of the above-mentioned (meth)acrylic acid alkyl ester monomers with other monomers copolymerizable therewith, such as (meth)acrylic acid, hydroxyalkyl esters of (meth)acrylic acid, vinyl acetate, styrene, vinylpyrrolidone, (meth)acrylamide, alkoxyalkyl (meth)acrylates, etc.

[0020] The adhesive rubber layer 2 has adhesiveness and can be used by sticking (pasting) it to the skin. The adhesiveness is such that it can be used without falling off even when stuck to the skin and used in daily life, and it can be easily peeled off by hand. After peeling the wound protection sheet 1 from the skin, it can be washed or disinfected with alcohol and then stuck again to the skin for use. In this way, the adhesive rubber layer 2 has an appropriate adhesive strength to the skin, so that the adhesive rubber layer 2 can be firmly stuck (pasted) and fixed to the skin, and the adhesive strength is less reduced when re-pasting, making it reworkable and durable.

[0021] The adhesiveness of the adhesive rubber layer 2 can be appropriately adjusted by the composition of the adhesive rubber layer 2 and the ratio of the composition.

[0022] The thickness of the adhesive rubber layer 2 is not particularly limited, but may be, for example, from 80 μm to 22,000 μm, and preferably from 100 μm to 3,500 μm.

[0023] The non-adhesive rubber layer 3 is a layer which forms one side of the surface of the wound protection sheet 1 which has a three-layer structure. It forms the surface opposite to the surface formed by the adhesive rubber layer 2. The non-adhesive rubber layer 3 may contain an adhesive resin and may further contain a water-repellent component. The adhesive resin is preferably a rubber-based adhesive, but is not limited thereto and may be, for example, an acrylic adhesive. The non-adhesive rubber layer 3 is formed by hardening the adhesive resin.

[0024] As the rubber-based adhesive, the same ones as those used for the adhesive rubber layer 2 can be used.

[0025] As the acrylic adhesive, the same ones as those used for the adhesive rubber layer 2 can be used.

[0026] The non-adhesive rubber layer 3 does not have enough adhesiveness to be able to be stuck to the skin when used, but does not have to be completely non-adhesive. In other words, it may have adhesiveness to the extent that it cannot be stuck to the skin or clothing when used (this may also be referred to as not being very adhesive). It may also be completely non-adhesive.

[0027] The adhesion of the non-adhesive rubber layer 3 can be appropriately adjusted by the composition of the non-adhesive rubber layer 3 and the ratio of the composition.

[0028] The thickness of the non-adhesive rubber layer 3 is not particularly limited, but may be, for example, from 80 μm to 22,000 μm, and preferably from 100 μm to 3,500 μm.

[0029] The non-adhesive rubber layer 3 is not very adhesive and does not stick to clothing, etc., improving the convenience of the wound protection sheet 1 in daily life. Furthermore, for example, when an affected area such as the shoulder or neck is covered with the surface of the wound protection sheet 1 on the adhesive rubber layer 2 side, the non-adhesive rubber layer 3 is placed on the side of the clothing being worn and comes into contact with the clothing. Since the non-adhesive rubber layer 3 is not very adhesive and does not stick to clothing, the wound protection sheet 1 does not stick to clothing and sticks only to the skin side where the affected area is located. This prevents the wound protection sheet 1 from sticking to places other than the intended location, and the effect of the wound protection sheet 1 can be obtained more stably.

[0030] The adhesive layer 4 is disposed between the adhesive rubber layer 2 and the non-adhesive rubber layer 3, and forms the second layer (middle layer) of the three-layer structure of the wound protection sheet 1. For example, there is a wound protection sheet 1 in which the adhesive layer 4 is disposed on the sheet-like non-adhesive rubber layer 3, and the adhesive rubber layer 2 is provided on the adhesive layer 4. In use, it is preferable that the adhesive layer 4 is not exposed on the outer surface. In this embodiment, the texture when it touches the skin etc. becomes more uniform, and the comfort in use is improved. Even if a portion of the adhesive layer 4 is exposed on the outer surface after curing, it does not have strong adhesiveness and does not provide the adhesive force for sticking (attaching) the wound protection sheet 1 to the skin, etc. In addition, it is not a factor in sticking to clothing, etc.

[0031] The adhesive layer 4 contains an adhesive resin. The adhesive resin is preferably a rubber-based adhesive, but is not limited thereto and may be, for example, an acrylic adhesive. The adhesive resin is cured to form the non-adhesive rubber layer 3. When the adhesive rubber layer 2 and the non-adhesive rubber layer 3 are formed of a rubber-based adhesive, it is preferable that the adhesive layer 4 is also formed of the same rubber-based adhesive, from the viewpoint of enhancing adhesion therebetween.

[0032] As the rubber-based adhesive, the same ones as those used for the adhesive rubber layer 2 and the non-adhesive rubber layer 3 can be used.

[0033] As the acrylic adhesive, the same ones as those used for the adhesive rubber layer 2 and the non-adhesive rubber layer 3 can be used.

[0034] The adhesive layer 4 is bonded to the adhesive rubber layer 2 and the non-adhesive rubber layer 3 on the surface on the adhesive rubber layer 2 side and the surface on the non-adhesive rubber layer 3 side, respectively. As a result, the adhesive rubber layer 2 and the non-adhesive rubber layer 3 are bonded via the adhesive layer 4. Since the adhesive rubber layer 2 and the non-adhesive rubber layer 3 are thus provided by stronger adhesion than close contact, the wound protection sheet 1 is less likely to peel off at the interface between the adhesive rubber layer 2 and the non-adhesive rubber layer 3, more precisely, at the interface between the adhesive rubber layer 2 and the adhesive layer 4 and the interface between the non-adhesive rubber layer 3 and the adhesive layer 4. That is, the wound protection sheet 1 of this embodiment is less likely to peel off.

[0035] The adhesiveness of the adhesive layer 4 can be appropriately adjusted by the composition of the adhesive layer 4 and the ratio of the composition.

[0036] The thickness of the adhesive layer 4 is not particularly limited, but may be, for example, from 40 μm to 6000 μm, and preferably from 30 μm to 1000 μm.

[0037] The wound protective sheet 1 may be coated or impregnated with other active ingredients, auxiliaries and / or dyes, etc. depending on the purpose. For example, if the wound protection sheet 1 is transparent, the affected area can be observed from the outside while the wound protection sheet is attached to the affected area. For example, if the wound protection sheet 1 is opaque, when the wound protection sheet is applied to an affected area, the affected area cannot be seen from the outside. The wound protective sheet 1 may be transparent, translucent or opaque.

[0038] The wound protection sheet 1 may have a fluorine-treated film or the like applied to its surface, as long as the adhesive rubber layer 2 can maintain sufficient adhesiveness to be used when attached (pasted) to the skin.

[0039] [Manufacturing method of wound protection sheet] The second aspect of the present invention is a method for producing a wound protection sheet. The method for producing a wound protection sheet 1, which is one example of an embodiment of this aspect, includes at least the steps of providing an uncured adhesive layer 4 on a non-adhesive rubber layer 3, and further providing an uncured adhesive rubber layer 2 on top of that. In this case, the non-adhesive rubber layer 3 may be either uncured or cured. In the method for producing a wound protection sheet of this embodiment, a wound protection sheet can be produced by the following steps 1 to 3.

[0040] Step 1: A paste or gel-like composition for the non-adhesive rubber layer 3 before curing is poured into a predetermined mold and applied. The applied paste-like non-adhesive rubber layer 3 hardens at room temperature, and forms a non-adhesive rubber layer 3 upon hardening.

[0041] After carrying out step 1, the process may immediately proceed to carrying out step 2, or may proceed to carrying out step 2 after a short time has elapsed. That is, at the stage of carrying out step 2, the paste-like or gel-like composition of the non-adhesive rubber layer 3 before curing that has been applied in step 1 may be cured, semi-cured, or cured. In this way, the process may proceed to step 2 regardless of the cured state of the composition that has been applied in step 1. When moving to step 2 after a short time has elapsed, for example, step 1 can be carried out multiple times to produce multiple non-adhesive rubber layers 3, and then moving to step 2. In this way, by being able to move to step 2 regardless of the cured state of the composition of the non-adhesive rubber layer 3 applied in step 1, the wound protection sheet 1 can be produced more efficiently without time constraints.

[0042] The reason why it is not limited by the cured state of the composition applied in step 1, in other words, it is not limited by the time until the composition of the non-adhesive rubber layer 3 cures, is because the adhesive layer 4 is provided in the subsequent step 2. In the past, when the adhesive layer 4 was not provided, it was necessary to immediately move to the next step and apply the composition of the adhesive rubber layer 3 before the composition of the non-adhesive rubber layer 3 applied in step 1 cures, in order to ensure that the non-adhesive rubber layer 3 and the adhesive rubber layer 2 are adhered to each other so as not to peel off. According to the manufacturing method of this embodiment, since the adhesive layer 4 having an adhesive effect is provided, it is possible to subsequently apply the composition of the adhesive rubber layer 2 on top of the composition of the non-adhesive rubber layer 3 applied in step 1 without being affected by the cured state of the composition. For example, even if the composition of the non-adhesive rubber layer 3 applied in step 1 has already cured to form the non-adhesive rubber layer 3, it is possible to adhere the non-adhesive rubber layer 3 and the adhesive rubber layer 2 via the adhesive layer 4 by applying the composition of the adhesive layer 4 on top of the composition of the non-adhesive rubber layer 3 and subsequently applying and curing the composition of the adhesive rubber layer 2. This eliminates the time restriction that the adhesive rubber layer 3, which is a rubber with high adhesiveness, must be molded before the non-adhesive rubber layer 3, which is a rubber with low adhesiveness, hardens.

[0043] Step 2: A paste-like composition for the adhesive layer 4 before hardening is applied onto the non-adhesive rubber layer 3 or the composition for the non-adhesive rubber layer 3. The composition of the non-adhesive rubber layer 3 applied in step 1 may be before curing and before the non-adhesive rubber layer 3 is molded, or after curing and after the non-adhesive rubber layer 3 is molded.

[0044] The applied paste-like adhesive layer 4 composition hardens at room temperature, and when hardened, forms the adhesive layer 4. The formed adhesive layer 4 after molding does not strongly adhere to a layer (e.g., viscous rubber layer 2) newly formed thereon. Therefore, before the adhesive layer 4 hardens, the adhesive layer 4 can be adhered to the adhesive layer 4 by curing the adhesive layer 4 in a state where the adhesive layer 4 is in contact with the layer to be adhered to the adhesive layer 4 or a layer on which the composition of the layer to be adhered is applied.

[0045] The layer to be bonded to the adhesive layer 4 does not need to be in a pre-cured state when it comes into contact with the adhesive layer 4, and may be in a cured state. This allows, for example, applying the pre-cured adhesive layer 4 on the cured non-adhesive rubber layer 3, and providing the cured adhesive rubber layer 2 on the pre-cured adhesive layer 4. That is, when providing the cured adhesive rubber layer 2, the adhesive rubber layer 2 is molded prior to step 2. In this case, the non-adhesive rubber layer 3 and the adhesive rubber layer 2 are molded, respectively, and then the non-adhesive rubber layer 3 and the adhesive rubber layer 2 are bonded via the molding of the adhesive layer 4, thereby manufacturing the wound protection sheet 1. In this way, by being able to bond the molded non-adhesive rubber layer 3 and the adhesive rubber layer 2, the molding of the non-adhesive rubber layer 3 and the adhesive rubber layer 2 can be performed in advance in multiple batches, and the wound protection sheet 1 can be manufactured more efficiently.

[0046] Step 3: A paste-like adhesive rubber layer 2 composition before curing is applied onto the adhesive layer 4 composition before curing. The applied adhesive rubber layer 2 in the form of a paste is cured at room temperature, and forms an adhesive rubber layer 2 when cured.

[0047] Step 3 is a step of applying a composition of a layer to be adhered, for example, an adhesive rubber layer 2, to the uncured adhesive layer 4. The adhesive rubber layer 2 may be a cured, molded adhesive rubber layer 2. [Explanation of symbols]

[0048] 1... wound protection sheet, 2... first adhesive rubber layer (adhesive rubber layer), 3... second adhesive rubber layer (non-adhesive rubber layer), 4... adhesive layer

Claims

1. A wound protection sheet comprising a first adhesive rubber layer having adhesiveness to skin, a second adhesive rubber layer having less adhesiveness to skin than the first adhesive rubber layer, and an adhesive layer, the adhesive layer is disposed between the first adhesive rubber layer and the second adhesive rubber layer, A wound protection sheet, in which the first adhesive rubber layer and the second adhesive rubber layer are bonded via the adhesive layer.

2. 2. The wound protection sheet according to claim 1, wherein the first adhesive rubber layer and the second adhesive rubber layer are cured products of condensation type silicone rubber that cures at room temperature.

3. A method for producing the wound protection sheet according to claim 1, comprising the steps of: providing the adhesive layer and the first adhesive rubber layer before curing on the second adhesive rubber layer, A method for producing a wound protection sheet, wherein the second adhesive rubber layer may be in a pre-cured state or a post-cured state.

4. 4. The method for producing a wound protection sheet according to claim 3, wherein the material of the first adhesive rubber layer and the second adhesive rubber layer is a condensation type silicone rubber that hardens at room temperature.

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