Biofilm therapeutic compositions

The charged biofilm formula, containing ions, an oxidizing agent, and Vitamin C, addresses the challenge of antimicrobial resistance in biofilm infections by inhibiting microbial growth and metabolism, providing an effective treatment for biofilm-related infections.

WO2025019857A1PCT designated stage expired Publication Date: 2025-01-23AZ SOLUTIONS LLC
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Patent Information

Application Number
PCT/US2024/038961
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-06-06
Filing Date
2024-07-22
Publication Date
2025-01-23

AI Technical Summary

Technical Problem

Conventional antibiotic treatments are ineffective against biofilm infections due to widespread antimicrobial resistance, posing a significant medical challenge in treating infectious diseases.

Method used

A charged biofilm formula comprising a source of ions (e.g., zinc compound), a source of an oxidizing agent (e.g., chlorite forming solution), and a source of Vitamin C (e.g., ascorbic acid), which are combined to inhibit the growth and metabolism of microorganisms at the site of biofilm infection.

Benefits of technology

The charged biofilm formula effectively inhibits the growth and metabolism of microorganisms, including bacteria, fungi, and viruses, thereby reducing or eliminating biofilm presence and treating infections effectively.

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Abstract

A biofilm treatment system including a delivery device housing a composition having a source of ions in the amount of about 25-225 mM and a source of an oxidizing agent in the amount of about 25-225 mM and a source of Vitamin C in the amount of about 1 mM to 10 mM, the composition being configured as a biofilm reducer.
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Citation Information

Patent Citations

  • Consumer Product Compositions

    US20150210964A1

  • Compositions, Methods And Devices For Promoting Wound Healing And Reducing Infection

    US20160030476A1

  • Methods of inhibiting microbial infections using zinc-containing compositions

    US20190388465A1

  • Photodynamic therapy compositions and methods of treatment therein

    US20220354953A1

  • Combination therapy for treating infections diseases

    WO2016154051A1