Cosmetic composition for lightening or whitening the skin
A cosmetic composition combining Japanese lily of the valley and yarrow extracts inhibits melanocytic dendrite elongation, addressing skin lightening and depigmentation challenges, achieving enhanced and long-lasting effects with additional active ingredients.
Patent Information
- Application Number
- PCT/SG2025/050014
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-01-11
- Filing Date
- 2025-01-08
- Publication Date
- 2025-07-17
AI Technical Summary
There is a need for cosmetic compositions that can effectively lighten, whiten, and depigment the skin using natural active ingredients in a lasting manner, addressing the pigmentary aspect of human epidermis influenced by melanin production and skin heterogeneity.
A cosmetic composition comprising Japanese lily of the valley and yarrow extracts, optionally combined with additional active ingredients like alpha arbutin, licorice root extract, and vitamin E, inhibits melanocytic dendrite elongation to reduce melanin production and transfer, providing a synergistic skin lightening, whitening, and depigmenting effect.
The composition achieves improved and lasting skin lightening, whitening, and depigmenting effects through inhibiting melanocytic dendrite elongation, enhancing skin elasticity and firmness, and offering anti-aging benefits.
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Abstract
Description
[0001] SPECIFICATION
[0002] TITLE: Cosmetic composition for lightening or whitening the skin
[0003] FIELD OF THE INVENTION
[0004] The technical field of the present invention is that of cosmetic compositions. The invention particularly concerns a cosmetic composition comprising a Japanese lily of the valley plant extract and a yarrow plant extract and its uses in the cosmetic field. More specifically, the invention concerns a cosmetic composition for lightening or whitening keratinous materials, particularly the skin.
[0005] STATE OF THE ART
[0006] The pigmentary aspect of human epidermis is influenced by several elements, including seasonal climates, ethnic origin and gender. It is primarily the specificity and density of melanin generated by melanocytes that is responsible for this. Melanocytes are cells dedicated to the production of melanin through specific organelles called melanosomes. Furthermore, it is not uncommon that during their lifetime, some people see dark and / or pigmented marks appear on their epidermis, particularly on their hands, thus creating cutaneous heterogeneity. Specialists in the field are constantly seeking to create products that make the skin lighter or whiter to try to meet a growing need from cosmetic product consumers.
[0007] Japanese lily of the valley is a perennial herbaceous plant, native to East Asia, known for its cosmetic virtues. It is now used in various cosmetic applications, particularly for its skin protective effect. It contains compounds such as polysaccharides, saponins, steroids, flavonoids and phenolic acids which give it moisturizing, antioxidant and antiinflammatory properties.
[0008] Yarrow is a plant traditionally used for its cosmetic properties. Its virtues are attributed to its active components, such as flavonoids, sesquiterpenes and tannins, which have antioxidant, anti-inflammatory properties and promote healing. Yarrow extract is recognized for stimulating the production of collagen and elastin by dermal fibroblasts, thus improving skin elasticity and firmness. It also promotes cell proliferation and migration, which accelerates skin renewal.
[0009] There is a need to provide new cosmetic compositions comprising natural active ingredients that can lighten, whiten and / or depigment keratinous materials, particularly the skin, in a lasting way.
[0010] SUMMARY OF THE INVENTION
[0011] The invention concerns a cosmetic composition for lightening or whitening the skin by inhibiting melanocytic dendrite elongation, comprising a Japanese lily of the valley extract and a yarrow extract.
[0012] According to one embodiment of the invention, the composition comprises between 0.05% by weight and 10% by weight of Japanese lily of the valley extract.
[0013] According to another embodiment of the invention, the composition comprises between 0.05% by weight and 10% by weight of yarrow extract.
[0014] According to yet another embodiment of the invention, the Japanese lily of the valley extract is a Japanese lily of the valley roots extract.
[0015] According to yet another embodiment of the invention, the yarrow extract is a of yarrow flowers or flowering tops extract.
[0016] According to yet another embodiment of the invention, the composition also comprises alpha arbutin, licorice root extract, glycyrrhetinic acid, vitamin E, 3-0 ethyl ascorbate, niacinamide, Halidrys Siliquosa extract, tranexamic acid, bakuchiol and / or hydroxypinacolone retinoate.
[0017] According to yet another embodiment of the invention, the composition is in the form of a gel, emulsion, cream, milk, lotion, serum, essence, oil, wax, stick, powder or encapsulated form.
[0018] The invention also concerns the cosmetic use of the composition according to the invention, for lightening or whitening the skin by inhibiting melanocytic dendrite elongation. The invention also concerns the cosmetic use of the composition according to the invention, for a depigmenting effect.
[0019] The invention also concerns the cosmetic use of the composition according to the invention, for an anti-aging effect.
[0020] The invention also concerns the non-therapeutic cosmetic use of a yarrow leaves extract and a Japanese lily of the valley roots extract as depigmenting, whitening and / or lightening agents for the skin.
[0021] A first advantage of the present invention lies in the skin whitening effect of the composition.
[0022] Another advantage of the present invention lies in the skin lightening effect of the composition.
[0023] Yet another advantage of the present invention lies in the skin depigmenting effect of the composition.
[0024] Yet another advantage of the present invention lies in the anti-aging effect of the composition.
[0025] Yet another advantage of the present invention lies in the use of natural active ingredients.
[0026] Yet another advantage of the present invention lies in the use of COSMOS certified active ingredients.
[0027] Other features, advantages and details of the invention will be better understood upon reading the following detailed description.
[0028] DETAILED DESCRIPTION
[0029] In the context of the present invention, "cosmetic composition" means a non-therapeutic cosmetic composition comprising one or more cosmetic active ingredients. A cosmetic active ingredient according to the invention refers to a set of molecules presenting non-therapeutic cosmetic efficacy on healthy skin. The cosmetic composition according to the invention is particularly suitable for lightening, whitening and / or depigmenting keratinous surfaces, particularly the skin.
[0030] In the context of the present invention, "extract" means a set of molecules extracted from a raw material, native or resulting from transformations. Thus, "Japanese lily of the valley extract" means a set of several molecules obtained by action on the plant raw material, in this case Japanese lily of the valley extract of the genus Ophiopogon and particularly of the species Ophiopogon japonicus. The Japanese lily of the valley extract is for example an extract obtained from the leaves, flowers, stems and / or roots of Japanese lily of the valley. According to one embodiment of the invention, the Japanese lily of the valley extract is an extract obtained from the roots of Japanese lily of the valley (INCI name: Ophiopogon Japonicus Root Extract). Furthermore, the Japanese lily of the valley extract according to the invention comprises molecules such as steroidal saponins, polysaccharides, flavonoids and homoisoflavonoids.
[0031] Thus, "yarrow extract" means a set of molecules obtained by action on the plant raw material, in this case yarrow of the genus Achillea and particularly of the species Achillea millefolium. The yarrow extract is for example an extract obtained from the leaves, flowers, stems and / or roots of yarrow. According to one embodiment of the invention, the yarrow extract is an extract obtained from the flowers or flowering tops of yarrow (INCI name: Achillea Millefolium Flower Extract). Furthermore, the yarrow extract according to the invention comprises molecules such as lactones, polyacetylenes and flavonoids.
[0032] In the context of the present invention, "keratinous material" means any biological material comprising keratin. Human skin and more particularly facial skin are particularly designated in the context of the present invention.
[0033] In the context of the present invention, "lightening or whitening the skin" means any action on the skin aimed at making it lighter or whiter, whether instantly or long-term. In cosmetics, this lightening or whitening effect is generally achieved by seeking to reduce the amount of melanin in the skin. The invention particularly allows for lightening or whitening the skin by inhibiting the elongation of melanocytic dendrites of melanocytes present in the skin.
[0034] In the context of the present invention, "melanocytic dendrite elongation" refers to the growth of these structures that are present in melanocytes, the cells producing the melanin pigment responsible for skin color. These dendrites play a key role in the transfer of melanin to surrounding cells. Inhibiting melanocytic dendrite elongation allows for limiting or preventing their growth, which reduces melanin production and transfer and therefore lightens, whitens and / or depigments the skin.
[0035] The present invention relates to a cosmetic composition comprising a Japanese lily of the valley extract and a yarrow extract. The inventor has surprisingly discovered that the association of the two active ingredients that are Japanese lily of the valley extract and yarrow extract provides a whitening, lightening and / or depigmenting effect on the skin to compositions containing them. Furthermore, the inventor has discovered that a composition comprising a Japanese lily of the valley extract and a yarrow extract allows for inhibiting melanocytic dendrite elongation of human melanocytes.
[0036] The cosmetic composition according to the invention presents cosmetic effects, particularly for lightening, whitening and / or depigmenting the skin, when used in topical application on the skin. The whitening, lightening and / or depigmenting effect on the skin is linked to a synergistic effect of the Japanese lily of the valley extract and the yarrow extract.
[0037] The Japanese lily of the valley extract is preferentially an extract obtained from the roots of Japanese lily of the valley. It is for example conditioned in an alcoholic solution. The Japanese lily of the valley extract according to the invention can be obtained by any suitable process known to those skilled in the art. According to one embodiment of the invention, the Japanese lily of the valley extract is a Japanese lily of the valley roots extract.
[0038] The yarrow extract is preferentially an extract obtained from yarrow flowers. It is for example conditioned in an aqueous solution comprising glycerin. The yarrow extract according to the invention can be obtained by any suitable process known to those skilled in the art. According to one embodiment of the invention, the yarrow extract is an extract of Achillea millefolium leaves or flowering tops.
[0039] The inventor has discovered that a cosmetic composition comprising a yarrow extract and between 0.05% and 10% by weight of Japanese lily of the valley extract presents an improved and lasting skin lightening or whitening effect. For example, the composition according to the invention comprises 0.05%, 0.1%, 0.3%, 0.5%, 0.7%, 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9% or 10% by weight of Japanese lily of the valley extract.
[0040] The inventor has discovered that a cosmetic composition comprising a Japanese lily of the valley extract and between 0.05% and 10% by weight of yarrow extract presents an improved and lasting skin lightening or whitening effect. For example, the composition according to the invention comprises 0.05%, 0.1%, 0.3%, 0.5%, 0.7%, 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9% or 10% by weight of yarrow extract.
[0041] Furthermore, a composition comprising between 0.05% and 10% by weight of yarrow extract and between 0.05% and 10% by weight of Japanese lily of the valley extract presents an improved and lasting skin lightening, whitening and / or depigmenting effect. The inventor has found that the synergistic effect of yarrow extract and Japanese lily of the valley extract is optimal when the cosmetic composition according to the invention comprises an equal amount of Japanese lily of the valley extract and yarrow extract, for example 5% by weight of Japanese lily of the valley extract and 5% by weight of yarrow extract.
[0042] Preferentially, the Japanese lily of the valley extract and the yarrow extract come from organic and ecological sources. According to one embodiment of the invention, the Japanese lily of the valley extract and the yarrow extract are COSMOS certified.
[0043] The cosmetic composition according to the invention is preferentially in the form of a gel, emulsion, cream, milk, lotion, serum, essence, oil, wax, stick, powder or encapsulated form. This allows adapting the composition according to the invention to any type of use and particularly to different skin types. For example, a composition in serum form is particularly suitable for topical application on facial skin. The composition according to the invention may comprise one or more cosmetically acceptable excipients. Optionally, said composition may contain one or more other additional cosmetic actives.
[0044] Thus, according to one embodiment of the invention, the composition comprises as additional active ingredient alpha arbutin, licorice root extract, glycyrrhetinic acid, vitamin E, 3-0 ethyl ascorbate, niacinamide, Halidrys Siliquosa extract, tranexamic acid, bakuchiol and / or hydroxypinacolone retinoate.
[0045] Alpha arbutin (INCI name: alpha-arbutin) is a hydroquinone derivative. Alpha arbutin allows blocking melanin synthesis by melanocytes by inhibiting tyrosinase activity. Furthermore, a composition according to the invention comprising Japanese lily of the valley extract, yarrow extract and alpha arbutin allows for lightening or whitening the skin not only by inhibiting melanocytic dendrite elongation, but also by inhibiting melanin synthesis. These are complementary modes of action, and the whitening or lightening effect of the cosmetic composition is then greatly improved, whether it be the instant or long-term effect. The composition according to the invention comprises between 0.1% and 5% by weight of alpha arbutin, preferentially 2% by weight.
[0046] Licorice root extract (INCI name: Glycyrrhiza Glabra Root Extract) is a lightening or depigmenting agent containing glabridin. It allows blocking melanin synthesis by melanocytes by inhibiting tyrosinase activity. Furthermore, a composition according to the invention comprising Japanese lily of the valley, yarrow extract and licorice root extract allows for lightening or whitening the skin not only by inhibiting melanocytic dendrite elongation, but also by inhibiting melanin synthesis. These are complementary modes of action, and the whitening or lightening effect of the cosmetic composition is then greatly improved, whether it be the instant or long-term effect. The composition according to the invention comprises between 0.1% and 5% by weight of licorice root extract, preferentially 2% by weight.
[0047] Glycyrrhetinic acid (INCI name: Glycyrrhetinic Acid) is a component of licorice root. Glycyrrhetinic acid also allows blocking melanin synthesis by melanocytes through inhibition of tyrosinase activity. Furthermore, a composition according to the invention comprising Japanese lily of the valley extract, yarrow extract and glycyrrhetinic acid extract allows for lightening or whitening the skin not only by inhibiting melanocytic dendrite elongation, but also by inhibiting melanin synthesis. These are complementary modes of action, and the whitening or lightening effect of the cosmetic composition is then greatly improved, whether it be the instant or long-term effect. The composition according to the invention comprises between 0.1% and 5% by weight of glycyrrhetinic acid, preferentially 2% by weight.
[0048] 3-0 ethyl ascorbate (INCI name: 3-0 Ethyl Ascorbic Acid) is a molecule derived from vitamin C, soluble in water and oil. 3-0 ethyl ascorbate allows inhibiting melanin production by melanocytes and depigmenting the skin. Furthermore, a composition according to the invention comprising Japanese lily of the valley, yarrow extract and 3-0 ethyl ascorbate allows for lightening or whitening the skin, not only by inhibiting melanocytic dendrite elongation, but also by inhibiting melanin synthesis. These are complementary modes of action, and the whitening or lightening effect of the cosmetic composition is then greatly improved, whether it be the instant or long-term effect. The composition according to the invention comprises between 0.1% and 5% by weight of 3-0 ethyl ascorbate, preferentially 2% by weight. This molecule also confers an anti-aging effect to the composition through its antioxidant properties.
[0049] Niacinamide (INCI name: Niacinamide) is a derivative of vitamin B3. Niacinamide allows inhibiting melanin transfer to keratinocytes and stimulating collagen synthesis, which helps whiten, lighten and reduce the appearance of skin pigmentation spots. Furthermore, a composition according to the invention comprising Japanese lily of the valley extract, yarrow extract and niacinamide allows for lightening or whitening the skin not only by inhibiting melanocytic dendrite elongation, but also by inhibiting melanin transfer to keratinocytes. These are complementary modes of action, and the whitening or lightening effect of the cosmetic composition is then greatly improved, whether it be the instant or long-term effect. The composition according to the invention comprises between 0.1% and 10% by weight of niacinamide, preferentially 7% by weight. This molecule also confers an anti-aging effect to the composition through its antioxidant properties.
[0050] Halidrys siliquosa (INCI name: Halidrys Siliquosa Extract) is a brown seaweed found particularly on the North-East Atlantic coasts. Halidrys siliquosa extract allows inhibiting melanin synthesis by decreasing tyrosinase activity. Halidrys siliquosa extract also allows inhibiting tyrosinase-related- protein 1 (TRP-1) activity and thus decreasing the amount of melanin transferred to keratinocytes. Furthermore, a composition according to the invention comprising Japanese lily of the valley extract, yarrow extract and Halidrys siliquosa extract allows for lightening or whitening the skin not only by inhibiting melanocytic dendrite elongation, but also by inhibiting melanin synthesis and melanin transfer to keratinocytes. These are complementary modes of action, and the whitening or lightening effect of the cosmetic composition is then greatly improved, whether it be the instant or longterm effect. The composition according to the invention comprises between 0.1% and 5% by weight of Halidrys siliquosa extract, preferentially 2% by weight.
[0051] Tranexamic acid (INCI name: Tranexamic Acid) is a synthetic analog of lysine. Tranexamic acid is a depigmenting agent that allows inhibiting tyrosinase activity and thus melanin production by melanocytes. Furthermore, a composition according to the invention comprising Japanese lily of the valley extract, yarrow extract and tranexamic acid allows for lightening or whitening the skin not only by inhibiting melanocytic dendrite elongation, but also by inhibiting melanin synthesis. These are complementary modes of action, and the whitening or lightening effect of the cosmetic composition is then greatly improved, whether it be the instant or long-term effect. The composition according to the invention comprises between 2% and 5% by weight of tranexamic acid, preferentially 3% by weight.
[0052] Bakuchiol (INCI name: Bakuchiol) is a compound derived from Babchi seeds. Bakuchiol allows reducing melanin synthesis by melanocytes. Furthermore, a composition according to the invention comprising Japanese lily of the valley extract, yarrow extract and bakuchiol allows for lightening or whitening the skin not only by inhibiting melanocytic dendrite elongation, but also by inhibiting melanin synthesis. These are complementary modes of action, and the whitening or lightening effect of the cosmetic composition is then greatly improved, whether it be the instant or long-term effect. The composition according to the invention comprises between 2% and 5% by weight of bakuchiol, preferentially 3% by weight. This molecule also confers an anti-aging effect to the composition through its antioxidant properties.
[0053] Hydroxypinacolone retinoate (INCI name: Hydroxypinacolone Retinoate) is a retinol derivative. Hydroxypinacolone retinoate is a depigmenting agent that allows inhibiting tyrosinase activity and thus melanin production by melanocytes. Furthermore, a composition according to the invention comprising Japanese lily of the valley extract, yarrow extract and hydroxypinacolone retinoate allows for lightening or whitening the skin not only by inhibiting melanocytic dendrite elongation, but also by inhibiting melanin synthesis. These are complementary modes of action, and the whitening or lightening effect of the cosmetic composition is then greatly improved, whether it be the instant or long-term effect. The composition according to the invention comprises between 0.1% and 5% by weight of hydroxypinacolone retinoate, preferentially 2% by weight.
[0054] Vitamin E (INCI name: Tocopherol) is known for its antioxidant properties. Vitamin E also allows reducing melanin production by inhibiting tyrosinase activity. Furthermore, a composition according to the invention comprising Japanese lily of the valley extract, yarrow extract and vitamin E allows for lightening or whitening the skin not only by inhibiting melanocytic dendrite elongation, but also by inhibiting melanin synthesis. These are complementary modes of action, and the whitening or lightening effect of the cosmetic composition is then greatly improved, whether it be the instant or long-term effect. The composition according to the invention comprises between 0.1% and 5% by weight of vitamin E, preferentially 2% by weight.
[0055] Furthermore, the cosmetic composition according to the invention presents cosmetic effects, particularly whitening, lightening, and skin depigmentation, when used in topical application on the skin. These effects are linked to a synergistic effect of the Japanese lily of the valley extract and the yarrow extract. The effects of the composition can also be reinforced by additional cosmetic active ingredients potentially present in the composition.
[0056] Furthermore, a combination comprising a yarrow leaves extract and a Japanese lily of the valley roots extract presents a whitening, lightening and / or depigmenting effect on the skin.
[0057] The inventor has conducted tests to demonstrate the inhibitory effect on melanocytic dendrite elongation of the composition according to the invention.
[0058] More particularly, the inventor evaluated the in vitro effect of 3 products on melanocytic dendrite elongation of human melanocytes (HEMAs), in the presence of UVB irradiation. The three products analyzed are the following:
[0059] - Product Pl: Japanese lily of the valley extract,
[0060] - Product P2: yarrow extract, and
[0061] - Product P3: solution comprising 50% by weight of Japanese lily of the valley extract and 50% by weight of yarrow extract.
[0062] The melanocytes are maintained in basal culture medium in an incubator at 5% CO2 and at a temperature of 37°C. The culture medium is changed every four days.
[0063] The melanocytes are cultured in medium allowing maintenance of cellular homeostasis. The melanocytes at low confluence are treated or not with one of products Pl to P3 at different concentrations: 0.01%, 0.1%, and 1%. After 24 hours of incubation with products Pl, P2, or P3, the culture supernatant is collected, and PBS buffer is deposited on the melanocytes. The cultures are then subjected or not to UVB irradiation (72 mJ / cm). The PBS culture supernatant is then collected and a 24-hour incubation of the cells in their culture medium is continued. The supernatant is then removed, and the cells are washed. The cells are then fixed with a paraformaldehyde solution. The observation of results is performed using a microscope.
[0064] The number of dendrites per cell and the length of each dendrite per cell are determined. This allows determining the average length of dendrites per cell which is then equal to the sum of the lengths of dendrites of a cell, divided by the number of dendrites of the cell.
[0065] The average length of dendrites is then compared to a control batch that has not undergone any treatment with one of products Pl to P3.
[0066] In the absence of UVB irradiation, the results are as follows:
[0067] [Table 1]
[0068] It is observed that product P3 shows greater inhibition than products Pl and P2, and this starting from a mass concentration of 0.1%.
[0069] This demonstrates the synergistic effect of Japanese lily of the valley extract and yarrow extract in inhibiting melanocytic dendrite elongation.A dose effect is also observed with increased inhibition when the concentration of product P3 increases from 0.1% by weight to 1% by weight.
[0070] Thus, in the absence of UVB irradiation and from a concentration greater than or equal to 0.1% by weight, the composition according to the invention allows inhibiting melanocytic dendrite elongation.
[0071] In the presence of UVB irradiation, the results are as follows:
[0072] [Table 2]
[0073] It is observed that product P3 shows greater inhibition than products Pl and P2, and this starting from a mass concentration of 0.1%.
[0074] This demonstrates the synergistic effect of Japanese lily of the valley extract and yarrow extract in inhibiting melanocytic dendrite elongation.A dose effect is also observed with increased inhibition when the concentration of product P3 increases from 0.1% by weight to 1% by weight.
[0075] Thus, in the presence of UVB irradiation and from a concentration greater than or equal to 0.1% by weight, the composition according to the invention allows inhibiting melanocytic dendrite elongation.
[0076] Moreover, it is observed that the average length of dendrites of melanocytes treated with product P3 at a concentration of 1% and in the presence of irradiation is lower than that of the non-irradiated control batch. The composition according to the invention allows compensating for the stimulating effect of UVB on the length of melanocytic dendrites.
[0077] The following description concerns examples of cosmetic compositions according to the invention.
[0078] Example 1: Depigmenting cosmetic cream.
[0079] The composition according to example 1 comprises the following ingredients.
[0080] [Table 3]
[0081] The composition according to example 1 is obtained according to the following operating method:
[0082] 1)Preparation of aqueous phase A (A = A1+A2+A3+A4): a. Mix the ingredients of phase Al, b. Bring mixture Al to a temperature of 75°C, c. Add phase A2 to phase Al, d. Stir mixture A1+A2, e. Add phase A3 to mixture A1+A2, f. Stir mixture A1+A2+A3, g. Add phase A4 to mixture A1+A2+A3, h. Stir mixture A1+A2+A3+A4.
[0083] 2)Preparation of the fat phase (phase B): a. Mix the ingredients of phase B, b. Heat phase B.
[0084] 3)Preparation of phase C: a. Mix the ingredients of phase C, b. Bring, under stirring, phase C to a temperature of 60°C.
[0085] 4)Preparation of phase D: a. Mix the ingredients of phase D, b. Stir phase D.
[0086] 5)Mix phase A and phase B and stir.
[0087] 6)Add phase C to mixture A+B at a temperature of 60°C.
[0088] 7)Add phase D to mixture A+B+C at a temperature of 60°C.
[0089] 8)Bring mixture A+B+C+D to room temperature.
[0090] 9)Prepare phase E by mixing the ingredients of phase E.
[0091] 10)Add phase E to mixture A+B+C+D.
[0092] 11)Prepare phase F by mixing the ingredients of phase
[0093] F.
[0094] 12)Add phase F to mixture A+B+C+D+E.
[0095] 13)Prepare phase G by mixing the ingredients of phase
[0096] G.
[0097] 14)Add phase G to mixture A+B+C+D+E+F. 15)Prepare phase H by mixing the ingredients of phase H.
[0098] 16)Add phase H to mixture A+B+C+D+E+F+G.
[0099] 17)Add the ingredients of phases I and J to mixture A+B+C+D+E+F+G+H.
[0100] 18)Add phase K to mixture A+B+C+D+E+F+G+H+I+J to obtain the composition according to example 1.
[0101] 19)Adjust, if necessary, the pH of the composition between 5 and 5.5 with phase L. Example 2: Depigmenting cosmetic serum.
[0102] The composition according to example 2 comprises the following ingredients.
[0103] [Table 4]
[0104]
[0105] The composition according to example 2 is obtained according to the following operating method:
[0106] 1)Preparation of aqueous phase A (A = A1+A2+A3+A4): a. Mix the ingredients of phase Al, b. Bring mixture Al to a temperature of 75°C, c. Add phase A2 to phase Al, d. Stir mixture A1+A2, e. Add phase A3 to mixture A1+A2, f. Stir mixture A1+A2+A3, g. Add phase A4 to mixture A1+A2+A3, h. Stir mixture A1+A2+A3+A4.
[0107] 2)Preparation of the fat phase (phase B): a. Mix the ingredients of phase B, b. Heat phase B.
[0108] 3)Preparation of phase C: a. Mix the ingredients of phase C, b. Bring, under stirring, phase C to a temperature of 60°C.
[0109] 4)Preparation of phase D: a. Mix the ingredients of phase D, b. Stir phase D.
[0110] 5)Mix phase A and phase B and stir.
[0111] 6)Add phase C to mixture A+B at a temperature of 60°C.
[0112] 7)Add phase D to mixture A+B+C at a temperature of 60°C.
[0113] 8)Bring mixture A+B+C+D to room temperature.
[0114] 9)Prepare phase E by mixing the ingredients of phase E.
[0115] 10) Add phase E to mixture A+B+C+D.
[0116] 11)Prepare phase F by mixing the ingredients of phase
[0117] F.
[0118] 12)Add phase F to mixture A+B+C+D+E.
[0119] 13)Prepare phase G by mixing the ingredients of phase G.
[0120] 14)Add phase G to mixture A+B+C+D+E+F.
[0121] 15)Add the ingredient of phase H to mixture A+B+C+D+E+F+G. 16)Prepare phase I by mixing the ingredients of phase
[0122] I.
[0123] 17)Add phase I to mixture A+B+C+D+E+F+G+H.
[0124] 18)Add the ingredients of phases J and K to mixture A+B+C+D+E+F+G+H+I. 19)Add phase L to mixture A+B+C+D+E+F+G+H+I+J+K to obtain the composition according to example 2.
[0125] 20)Adjust, if necessary, the pH of the composition between 5 and 5.5 with phase M.
[0126] Example 3: Depigmenting cosmetic serum. The composition according to example 3 comprises the following ingredients.
[0127] [Table 5]
[0128]
[0129] The composition according to example 3 is obtained according to the following operating method:
[0130] 1)Preparation of aqueous phase A (A = A1+A2+A3+A4): a. Mix the ingredients of phase Al, b. Bring mixture Al to a temperature of 75°C, c. Add phase A2 to phase Al, d. Stir mixture A1+A2, e. Add phase A3 to mixture A1+A2, f. Stir mixture A1+A2+A3, g. Add phase A4 to mixture A1+A2+A3, h. Stir mixture A1+A2+A3+A4.
[0131] 2)Preparation of the fat phase (phase B): a. Mix the ingredients of phase B, b. Heat phase B.
[0132] 3)Preparation of phase C: a. Mix the ingredients of phase C, b. Bring, under stirring, phase C to a temperature of 60°C.
[0133] 4)Preparation of phase D: a. Mix the ingredients of phase D, b. Stir phase D.
[0134] 5)Mix phase A and phase B and stir.
[0135] 6)Add phase C to mixture A+B at a temperature of 60°C.
[0136] 7)Add phase D to mixture A+B+C at a temperature of 60°C.
[0137] 8)Bring mixture A+B+C+D to room temperature.
[0138] 9)Prepare phase E by mixing the ingredients of phase E.
[0139] 10)Add phase E to mixture A+B+C+D. 11)Prepare phase F by mixing the ingredients of phase
[0140] F.
[0141] 12)Add phase F to mixture A+B+C+D+E.
[0142] 13)Prepare phase G by mixing the ingredients of phase
[0143] G.
[0144] 14)Add phase G to mixture A+B+C+D+E+F.
[0145] 15)Add the ingredients of phases H and I to mixture A+B+C+D+E+F+G.
[0146] 16)Prepare phase J by mixing the ingredients of phase J.
[0147] 17)Add phase J to mixture A+B+C+D+E+F+G+H+I.
[0148] 18)Add the ingredients of phases K and L to mixture A+B+C+D+E+F+G+H+I+J.
[0149] 19)Add phase M to mixture A+B+C+D+E+F+G+H+I+J+K+L to obtain the composition according to example 3.
[0150] 20)Adjust, if necessary, the pH of the composition between 5 and 5.5 with phase N.
[0151] Example 4: Depigmenting cosmetic cream.
[0152] The composition according to example 4 comprises the following ingredients.
[0153] [Table 6]
[0154] The composition according to example 4 is obtained according to the following operating method:
[0155] 1)Preparation of aqueous phase A (A = A1+A2+A3+A4): a. Mix the ingredients of phase Al, b. Bring mixture Al to a temperature of 75°C, c. Add phase A2 to phase Al, d. Stir mixture A1+A2, e. Add phase A3 to mixture A1+A2, f. Stir mixture A1+A2+A3, g. Add phase A4 to mixture A1+A2+A3, h. Stir mixture A1+A2+A3+A4.
[0156] 2)Preparation of the fat phase (phase B): a. Mix the ingredients of phase B, b. Heat phase B.
[0157] 3)Preparation of phase C: a. Mix the ingredients of phase C, b. Bring, under stirring, phase C to a temperature of 60°C.
[0158] 4)Preparation of phase D: a. Mix the ingredients of phase D, b. Stir phase D.
[0159] 5)Mix phase A and phase B and stir.
[0160] 6)Add phase C to mixture A+B at a temperature of 60°C.
[0161] 7)Add phase D to mixture A+B+C at a temperature of 60°C.
[0162] 8)Bring mixture A+B+C+D to room temperature. 9)Prepare phase E by mixing the ingredients of phase E.
[0163] 10)Add phase E to mixture A+B+C+D.
[0164] 11)Prepare phase F by mixing the ingredients of phase
[0165] F.
[0166] 12)Add phase F to mixture A+B+C+D+E.
[0167] 13)Prepare phase G by mixing the ingredients of phase
[0168] G.
[0169] 14)Add phase G to mixture A+B+C+D+E+F.
[0170] 15)Prepare phase H by mixing the ingredients of phase
[0171] H.
[0172] 16)Add phase H to mixture A+B+C+D+E+F+G.
[0173] 17)Add the ingredients of phases I and J to mixture A+B+C+D+E+F+G+H.
[0174] 18)Add phase K to mixture A+B+C+D+E+F+G+H+I+J to obtain the composition according to example 4.
[0175] 19)Adjust, if necessary, the pH of the composition between 5 and 5.5 with phase L.
[0176] Example 5: Depigmenting cosmetic serum.
[0177] The composition according to example 5 comprises the following ingredients.
[0178] [Table 7]
[0179] The composition according to example 5 is obtained according to the following operating method:
[0180] 1)Preparation of aqueous phase A (A = A1+A2+A3+A4): a. Mix the ingredients of phase Al, b. Bring mixture Al to a temperature of 75°C, c. Add phase A2 to phase Al, d. Stir mixture A1+A2, e. Add phase A3 to mixture A1+A2, f. Stir mixture A1+A2+A3, g. Add phase A4 to mixture A1+A2+A3, h. Stir mixture A1+A2+A3+A4.
[0181] 2)Preparation of the fat phase (phase B): a. Mix the ingredients of phase B, b. Heat phase B.
[0182] 3)Preparation of phase C: a. Mix the ingredients of phase C, b. Bring, under stirring, phase C to a temperature of 60°C.
[0183] 4)Preparation of phase D: a. Mix the ingredients of phase D, b. Stir phase D.
[0184] 5)Mix phase A and phase B and stir.
[0185] 6)Add phase C to mixture A+B at a temperature of 60°C.
[0186] 7)Add phase D to mixture A+B+C at a temperature of 60°C. 8)Bring mixture A+B+C+D to room temperature.
[0187] 9)Prepare phase E by mixing the ingredients of phase E.
[0188] 10)Add phase E to mixture A+B+C+D.
[0189] 11)Prepare phase F by mixing the ingredients of phase
[0190] F.
[0191] 12)Add phase F to mixture A+B+C+D+E.
[0192] 13)Prepare phase G by mixing the ingredients of phase
[0193] G.
[0194] 14)Add phase G to mixture A+B+C+D+E+F.
[0195] 15)Add the ingredients of phases H and I to mixture A+B+C+D+E+F+G.
[0196] 16)Prepare phase J by mixing the ingredients of phase J.
[0197] 17)Add phase J to mixture A+B+C+D+E+F+G+H+I.
[0198] 18)Add the ingredients of phases K and L to mixture A+B+C+D+E+F+G+H+I+J.
[0199] 19)Add phase M to mixture A+B+C+D+E+F+G+H+I+J+K+L to obtain the composition according to example 5.
[0200] 20)Adjust, if necessary, the pH of the composition between 5 and 5.5 with phase N.
[0201] The invention furthermore concerns the use as a cosmetic depigmenting, whitening and / or lightening agent, of a combination comprising an extract of Achillea millefolium leaves and an extract of Ophiopogon japonicus roots.
Claims
CLAIMS1. Cosmetic composition for lightening or whitening the skin by inhibiting melanocytic dendrite elongation, comprising a Japanese lily of the valley extract and yarrow extract.
2. Cosmetic composition according to claim 1, characterized in that it comprises between 0.05% by weight and 10% by weight of Japanese lily of the valley extract.
3. Cosmetic composition according to claim 1 or 2, characterized in that it comprises between 0.05% by weight and 10% by weight of yarrow extract.
4. Cosmetic composition according to any one of the preceding claims, characterized in that the Japanese lily of the valley extract is a Japanese lily of the valley roots extract.
5. Cosmetic composition according to any one of the preceding claims, characterized in that the yarrow extract is a yarrow flowers or flowering tops extract.
6. Cosmetic composition according to any one of the preceding claims, characterized in that it also comprises alpha arbutin, licorice root extract, glycyrrhetinic acid, vitamin E, 3-0 ethyl ascorbate, niacinamide, Halidrys Siliquosa extract, tranexamic acid, bakuchiol and / or hydroxypinacolone retinoate.
7. Cosmetic composition according to any one of the preceding claims, characterized in that it is in the form of a gel, emulsion, cream, milk, lotion, serum, essence, oil, wax, stick, powder or encapsulated form.
8. Cosmetic use of a composition according to any one of the preceding claims, for lightening or whitening the skin by inhibiting melanocytic dendrite elongation.
9. Cosmetic use of a composition according to any one of claims 1 to 7, for a depigmenting effect.
10. Cosmetic use of a yarrow leaves extract and a Japanese lily of the valley roots extract as depigmenting, whitening and / or lightening agents for the skin.
Citation Information
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