High-barrier double-sealed vial

Abstract

A high-barrier double-sealed vial, comprising a vial body (100) and a cap body (200). The cap body (200) comprises a mounting main body (210), an accommodating part (220) arranged on the mounting main body (210), an accommodating cavity formed in the accommodating part (220), a rubber plug (230) arranged in the accommodating cavity, a first sealing structure (300) arranged on a first end part of the accommodating part (220), a second sealing structure (400) arranged on a second end part of the accommodating part (220), a first ring part (240) and a second ring part (250) which are spaced on the mounting main body (210) in the radial direction, and a first sealing ring (260) arranged between the first ring part (240) and the second ring part (250). A second sealing ring (400) is arranged on the end part of the second ring part (250) distant from the mounting main body (210); a sealing step (110) extending outwards in the radial direction is arranged on the outer wall of the vial body (100); and a first barrier layer is arranged on the outer wall of the cap body (200), and a second barrier layer is arranged on the outer wall of the vial body (100). The high-barrier double-sealed vial achieves low manufacturing costs, has good barrier properties and high practicability, and is suitable for wide popularization and application.

Description

High barrier double-sealed vials Technical Field

[0001] The invention relates to the technical field of pharmaceutical packaging, in particular to a high-barrier double-sealed penicillin bottle. Background Art

[0002] Vials are commonly used to package vaccines, powder injections, biologics, freeze-dried medicines, and other medicines. They are a widely used pharmaceutical packaging container. Existing vials are usually made of borosilicate glass or soda-lime glass. For example, Chinese utility model patent CN220164630U discloses a bottle mouth sealing structure and a glass vial. Although glass vials have good barrier properties, the cost of raw materials is relatively high. If the vial is made of plastic, although the cost of raw materials can be reduced, the barrier properties do not meet the requirements of pharmaceutical packaging.

[0003] In addition, the vial needs to be used in conjunction with an injection needle. When the injection needle punctures the vial, a rubber plug needs to be provided in the cap of the vial to hold the injection needle tightly and seal it to ensure the safety of medication. Therefore, the sealing of the rubber plug in the cap is very critical. On the one hand, the rubber plug must be prevented from contacting the drug, or the compatibility between the rubber plug and the drug must be ensured to avoid the rubber plug affecting the quality of the drug. On the other hand, the rubber plug must be prevented from contacting the external environment to avoid pathogens adhering to the rubber plug and being brought into the drug when punctured by the injection needle. However, existing vials are usually sealed with an aluminum-plastic composite cap. To prevent the rubber plug from affecting the quality of the drug, the rubber plug in the aluminum-plastic composite cap is a film-coated butyl rubber plug. The end face of the film-coated butyl rubber plug that contacts the drug is covered with a barrier film with stable performance and good compatibility with the drug. However, the production process of the film-coated butyl rubber plug is complicated and the process cost is high, which will increase the manufacturing cost of the vial.

[0004] Summary of the Invention

[0005] The present invention provides a high-barrier double-sealed vial to solve the technical problems of high manufacturing cost or poor barrier property of existing vials.

[0006] According to one aspect of the present invention, a high-barrier double-sealed penicillin bottle is provided, comprising a bottle body for containing medicines and a cover body for sealing the bottle mouth of the bottle body, the cover body comprising a mounting body, a accommodating portion arranged on the mounting body, a accommodating cavity opened in the accommodating portion, a rubber plug arranged in the accommodating cavity, a first sealing structure arranged on a first end portion of the accommodating portion for sealing the first end of the accommodating cavity, a second sealing structure arranged on a second end portion of the accommodating portion for sealing the second end of the accommodating cavity, a first ring portion and a second ring portion arranged on the mounting body at intervals along a radial direction, and a first sealing ring arranged between the first ring portion and the second ring portion for tightly sealing with the upper end surface of the bottle body, the inner wall of the first ring portion is used to fit and seal with the inner wall of the bottle body, the inner wall of the second ring portion is used to clamp and connect with the outer wall of the cover, a sealing step extending radially outward is provided on the outer wall of the bottle body, a second sealing ring for elastically abutting and sealing with the sealing step is provided on the end of the second ring portion away from the mounting body, a barrier layer 1 is provided on the outer wall of the cover body, and a barrier layer 2 is provided on the outer wall of the bottle body.

[0007] As a further improvement of the above technical solution:

[0008] Furthermore, the rubber plug can be detachably arranged in the accommodating cavity, and the cover body also includes a first fixing structure arranged on the first end of the accommodating portion and a second fixing structure arranged on the second end of the accommodating portion for cooperating with the first fixing structure to fix the rubber plug. The first sealing structure is arranged on the first fixing structure, and the second sealing structure is arranged on the second fixing structure.

[0009] Furthermore, the first end of the accommodating portion is arranged facing away from the bottle body, and the first fixing structure is a pressing edge bent and arranged on the first end of the accommodating portion for pressing the first end of the plug; or the first fixing structure is a first clamping portion that is clamped and connected to the first end of the accommodating portion for pressing the first end of the plug.

[0010] Furthermore, the second end of the accommodating portion is arranged toward the bottle body, and the second fixing structure is a supporting edge for supporting the second end of the plug, which is integrally injection molded with the second end of the accommodating portion; or the second fixing structure is a second clamping portion for supporting the second end of the plug, which is clamped and connected to the second end of the accommodating portion.

[0011] Furthermore, the second end of the accommodating portion is arranged toward the bottle body, and a sinking portion for increasing the distance between the rubber plug and the second sealing structure is arranged on the second fixing structure.

[0012] Furthermore, the inner wall matrix of the accommodating portion and the matrix of the rubber plug are bonded and compatible connected.

[0013] Furthermore, the first end portion of the accommodating portion is arranged facing away from the bottle body, and the first sealing structure is a first sealing film, a foldable cap or a pull ring.

[0014] Furthermore, the second end of the accommodating portion is arranged toward the bottle body, and the second sealing structure is a second sealing film or a sealing portion.

[0015] Furthermore, a clamping protrusion is provided on the inner wall of the second ring portion, and a clamping boss that is clamped and matched with the clamping protrusion is provided on the outer wall of the bottle body.

[0016] Furthermore, a freeze-drying tank is provided on the first ring portion.

[0017] The present invention has the following beneficial effects:

[0018] The high-barrier double-sealed penicillin bottle of the present invention contains medicines through the bottle body and seals the bottle mouth of the bottle body through the cover body to achieve sealed packaging of the medicine. The cover body is specifically provided with a mounting portion on the mounting main body, and a receiving cavity is provided on the receiving portion to accommodate the plug, so that the injection needle can pierce the plug. The first end and the second end of the receiving cavity are sealed respectively by the first sealing structure and the second sealing structure to cooperate with the receiving portion to achieve all-round sealing of the plug. The plug does not contact the medicine, and the compatibility between the cover body and the medicine is good. When the injection needle punctures, the injection needle is tightly sealed by the plug. The first ring part and the second ring part cooperate to make the cover body clamped and fixed on the bottle body. The sealing ring is in contact with and sealed against the upper end surface of the bottle body to prevent the medicine bottle in the bottle body from leaking outward from the bottle mouth of the bottle body, and then the second sealing ring and the sealing step are elastically contacted and sealed to prevent external pathogens from penetrating from the outside to the inside, realizing double sealing inside and outside with good sealing performance. After the barrier layer 1 and the barrier layer 2 are formed, the barrier layer 1 and the barrier layer 2 can fully cover the penicillin bottle, thereby maximizing the barrier property of the penicillin bottle. This solution realizes the sealing of the stopper from the structural level and improves the barrier property of the penicillin bottle, so that the penicillin bottle can be made of low-cost materials such as plastic. Compared with the existing technology, the penicillin bottle has low manufacturing cost, good barrier property, strong practicality, and is suitable for wide promotion and application.

[0019] In addition to the above-described objects, features and advantages, the present invention has other objects, features and advantages. The present invention will be further described in detail below with reference to the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] The accompanying drawings, which constitute part of this application, are intended to provide a further understanding of the present invention. The exemplary embodiments of the present invention and their descriptions are intended to explain the present invention and do not constitute an undue limitation of the present invention. In the accompanying drawings:

[0021] FIG1 is a schematic structural diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0022] FIG2 is a schematic cross-sectional view of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0023] FIG3 is a schematic cross-sectional view of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0024] FIG4 is a schematic cross-sectional view of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0025] FIG5 is a schematic cross-sectional view of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0026] FIG6 is a schematic cross-sectional view of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0027] FIG7 is a schematic cross-sectional view of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0028] FIG8 is a cross-sectional schematic diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0029] FIG9 is a schematic cross-sectional view of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0030] 10 is a schematic cross-sectional view of a high barrier double-sealed vial according to a preferred embodiment of the present invention;

[0031] FIG11 is a schematic cross-sectional view of a high barrier double-sealed vial according to a preferred embodiment of the present invention;

[0032] FIG12 is a schematic cross-sectional view of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0033] 13 is a cross-sectional schematic diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0034] FIG14 is a cross-sectional schematic diagram of a high barrier double-sealed vial according to a preferred embodiment of the present invention;

[0035] FIG15 is a cross-sectional schematic diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0036] FIG16 is a cross-sectional schematic diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0037] FIG17 is a cross-sectional schematic diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0038] FIG18 is a schematic cross-sectional view of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0039] FIG19 is a cross-sectional schematic diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0040] FIG20 is a cross-sectional schematic diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0041] FIG21 is a cross-sectional schematic diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0042] FIG22 is a cross-sectional schematic diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0043] FIG23 is a cross-sectional schematic diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0044] FIG24 is a cross-sectional schematic diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention;

[0045] Figure 25 is a cross-sectional schematic diagram of a high-barrier double-sealed penicillin bottle according to a preferred embodiment of the present invention.

[0046] Legend: 100, bottle body; 110, sealing step; 120, snap-fitting boss; 200, cover body; 210, mounting body; 220, accommodating portion; 230, rubber plug; 240, first ring portion; 241, freeze-drying tank; 250, second ring portion; 251, snap-fitting protrusion; 260, first sealing ring; 270, second sealing ring; 300, first sealing structure; 310, first sealing membrane; 320, foldable cap; 330, pull ring; 400, second sealing structure; 410, second sealing membrane; 420, sealing portion; 500, first fixing structure; 510, pressing edge; 520, first holding portion; 600, second fixing structure; 610, supporting edge; 620, second holding portion; 630, sinking portion. DETAILED DESCRIPTION

[0047] The embodiments of the present invention are described in detail below with reference to the accompanying drawings. However, the present invention can be implemented in many different ways as defined and covered below.

[0048] FIG1 is a schematic structural diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention; FIG2 is a schematic cross-sectional diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention; FIG3 is a schematic cross-sectional diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention; FIG4 is a schematic cross-sectional diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention; FIG5 is a schematic cross-sectional diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention; FIG6 is a schematic cross-sectional diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention; FIG7 is a schematic cross-sectional diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention FIG8 is a schematic cross-sectional view of a high-barrier double-sealed vial of a preferred embodiment of the present invention; FIG9 is a schematic cross-sectional view of a high-barrier double-sealed vial of a preferred embodiment of the present invention; FIG10 is a schematic cross-sectional view of a high-barrier double-sealed vial of a preferred embodiment of the present invention; FIG11 is a schematic cross-sectional view of a high-barrier double-sealed vial of a preferred embodiment of the present invention; FIG12 is a schematic cross-sectional view of a high-barrier double-sealed vial of a preferred embodiment of the present invention; FIG13 is a schematic cross-sectional view of a high-barrier double-sealed vial of a preferred embodiment of the present invention. FIG14 is a cross-sectional schematic diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention; FIG15 is a cross-sectional schematic diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention; FIG16 is a cross-sectional schematic diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention; FIG17 is a cross-sectional schematic diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention; FIG18 is a cross-sectional schematic diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention; FIG19 is a cross-sectional schematic diagram of a high-barrier double-sealed vial according to a preferred embodiment of the present invention. Schematic cross-section diagram; Figure 20 is a schematic cross-section diagram of a high-barrier double-sealed penicillin vial according to a preferred embodiment of the present invention; Figure 21 is a schematic cross-section diagram of a high-barrier double-sealed penicillin vial according to a preferred embodiment of the present invention; Figure 22 is a schematic cross-section diagram of a high-barrier double-sealed penicillin vial according to a preferred embodiment of the present invention; Figure 23 is a schematic cross-section diagram of a high-barrier double-sealed penicillin vial according to a preferred embodiment of the present invention; Figure 24 is a schematic cross-section diagram of a high-barrier double-sealed penicillin vial according to a preferred embodiment of the present invention; Figure 25 is a schematic cross-section diagram of a high-barrier double-sealed penicillin vial according to a preferred embodiment of the present invention.

[0049] Example 1

[0050] As shown in Figures 1 and 2, the high-barrier double-sealed penicillin bottle of this embodiment includes a bottle body 100 for containing medicines and a cover body 200 for sealing the bottle mouth of the bottle body 100. The cover body 200 includes a mounting body 210, a receiving portion 220 arranged on the mounting body 210, a receiving cavity opened in the receiving portion 220, a plug 230 arranged in the receiving cavity, a first sealing structure 300 arranged on a first end of the receiving portion 220 for sealing the first end of the receiving cavity, a second sealing structure 400 arranged on a second end of the receiving portion 220 for sealing the second end of the receiving cavity, and a plurality of sealing members 300 arranged on the mounting body 210 at intervals along the radial direction. The first ring portion 240 and the second ring portion 250 on the bottle body 100, and the first sealing ring 260 arranged between the first ring portion 240 and the second ring portion 250 for sealing tightly with the upper end surface of the bottle body 100, the inner wall of the first ring portion 240 is used to fit and seal with the inner wall of the bottle body 100, and the inner wall of the second ring portion 250 is used to be clamped and connected with the outer wall of the cover body 200, and a sealing step 110 extending radially outward is provided on the outer wall of the bottle body 100, and a second sealing ring 270 for elastically abutting and sealing with the sealing step 110 is provided on the end of the second ring portion 250 away from the installation body 210, a barrier layer 1 is provided on the outer wall of the cover body 200, and a barrier layer 2 is provided on the outer wall of the bottle body 100. Specifically, the high-barrier double-sealed vial of the present invention contains medicines through the bottle body 100, and then seals the bottle mouth of the bottle body 100 through the cover body 200 to achieve sealed packaging of the medicines. The cover body 200 is specifically arranged on the installation body 210 by arranging a mounting portion, and accommodating a plug 230 by opening an accommodating cavity on the accommodating portion 220, so that the injection needle can pierce the plug 230. Then, the first sealing structure 300 and the second sealing structure 400 respectively seal the first end and the second end of the accommodating cavity to cooperate with the accommodating portion 220 to achieve all-round sealing of the plug 230. The plug 230 does not contact the medicine. The compatibility between the cover body 200 and the medicine is good, and when the injection needle punctures, the plug 230 is used to tightly seal the injection needle. Then, the first ring portion 240 and the second ring portion 250 cooperate to make the cover The body 200 is snap-fitted and fixed on the bottle body 100, and the first sealing ring 260 is in contact and sealed with the upper end surface of the bottle body 100 to prevent the medicine bottle in the bottle body 100 from leaking outward from the bottle mouth of the bottle body 100, and then the second sealing ring 270 and the sealing step 110 are elastically contacted and sealed to prevent external pathogens from penetrating from the outside to the inside, realizing double sealing inside and outside, with good sealing performance, and after the barrier layer 1 and the barrier layer 2 are formed, the barrier layer 1 and the barrier layer 2 can achieve full coverage of the syringe bottle, thereby maximizing the barrier property of the syringe bottle. This solution realizes the sealing of the stopper 230 from the structural level and improves the barrier property of the syringe bottle, so that the syringe bottle can be made of low-cost materials such as plastic. Compared with the existing technology, the syringe bottle has low manufacturing cost, good barrier property, strong practicality, and is suitable for wide promotion and application.Optionally, the second sealing ring 270 and the second ring portion 250 are integrally formed using a two-material injection molding process. It should be understood that the two-material injection molding process is a well-known technique for those skilled in the art and will not be described in detail here. It should be understood that the abutment and sealing between the second sealing ring 270 and the sealing step 110 can also reduce the difficulty and cost of forming the barrier layer 1 and the barrier layer 2. The barrier layer 1 can be first plated on the outer wall of the cap 200, and then the cap 200 and the bottle 100 are assembled. The cap 200 of the vial is then turned downward, and the outer plating process is then performed to plate the barrier layer 2 on the outer wall of the bottle 100. Compared to the existing method of assembling the cap 200 and the bottle 100, first facing upward, applying the outer plating for the first time, then flipping the vial so that the cap 200 of the vial faces downward, and then applying the outer plating for the second time, the outer plating area is greatly reduced. Optionally, the first sealing ring 260 and / or the second sealing ring 260 are made of an elastic material such as rubber to achieve elastic extrusion-fit sealing.

[0051] As shown in Figures 1 and 2, in this embodiment, the plug 230 is detachably arranged in the accommodating cavity, and the cover body 200 also includes a first fixing structure 500 arranged on the first end of the accommodating portion 220 and a second fixing structure 600 arranged on the second end of the accommodating portion 220 for cooperating with the first fixing structure 500 to fix the plug 230. The first sealing structure 300 is arranged on the first fixing structure 500, and the second sealing structure 400 is arranged on the second fixing structure 600. Specifically, after the plug 230 is assembled in the accommodating cavity, the first fixing structure 500 and the second fixing structure 600 cooperate to fix the plug 230 to prevent the plug 230 from being brought into the bottle body 100 when the injection needle punctures the plug 230, or from being brought out of the bottle body 100 when the injection needle is pulled out. The first sealing structure 300 and the second sealing structure 400 cooperate to seal the plug 230 to prevent the plug 230 from being contaminated by the external environment and to avoid contact between the plug 230 and the drug.

[0052] As shown in Figures 1 and 2, in this embodiment, the first end of the accommodating portion 220 is arranged facing away from the bottle body 100, and the first fixing structure 500 is a bead 510 bent and arranged on the first end of the accommodating portion 220 for pressing against the first end of the plug 230. Specifically, during the injection molding process, the first end of the accommodating portion 220 is first injection-molded axially upward to form an unbent bead 510. After the injection molding is completed, the bead 510 is then bent and formed by hot pressing to press against the plug 230 and secure the plug 230 within the accommodating cavity. During the hot pressing process, the base density of the bead 510 increases, and the bead 510 is tightly fitted to the first end face of the plug 230, ensuring reliable fixation.

[0053] As shown in Figures 1 and 2, in this embodiment, the second end of the receiving portion 220 is arranged toward the bottle body 100, and the second fixing structure 600 is a supporting edge 610 that is integrally injection-molded with the second end of the receiving portion 220 and is used to support the second end of the plug 230. Specifically, the supporting edge 610 supports the second end of the plug 230 to cooperate with the pressing edge 510 to secure the plug 230.

[0054] As shown in Figures 1 and 2, in this embodiment, the second end of the accommodating portion 220 is arranged toward the bottle body 100, and a sinking portion 630 is provided on the second fixing structure 600 for increasing the distance between the rubber plug 230 and the second sealing structure 400. Specifically, by providing the sinking portion 630 in an annular shape on the supporting edge 610, the distance between the rubber plug 230 and the second sealing structure 400 is increased by the sinking portion 630, so that the needle tip of the injection needle has sufficient space to extend before puncturing the second sealing structure 400, thereby greatly reducing the puncture resistance and minimizing or avoiding the generation of insoluble particles. Even if insoluble particles are generated, they will be blocked in the cavity space enclosed by the sinking portion 630 and the second sealing structure 400 and will not be brought into the bottle body 100.

[0055] As shown in Figures 1 and 2, in this embodiment, the first sealing structure 300 is a first sealing film 310 welded to the pressing edge 510. Specifically, the first sealing film 310 is convenient for the operator to open, thereby facilitating injection needle puncture.

[0056] As shown in Figures 1 and 2, in this embodiment, the second sealing structure 400 is a sealing portion 420 integrally injection-molded with the lower end of the sinking portion 630. Specifically, the sealing portion 420 and the lower end of the sinking portion 630 are integrally injection-molded, providing a reliable seal and minimizing contact between the plug 230 and the drug. Furthermore, the sealing portion 420 can be made of plastic, which provides good compatibility with the drug.

[0057] As shown in Figures 1 and 2, in this embodiment, the inner wall of the second ring portion 250 is provided with a snap-fitting protrusion 251, and the outer wall of the bottle body 100 is provided with a snap-fitting boss 120 that snaps with the snap-fitting protrusion 251. Specifically, the snap-fitting protrusion 251, the second ring portion 250, the first sealing ring 260, and the first ring portion 240 cooperate to form a snap-fitting groove that snaps with the snap-fitting boss 120, thereby snapping and fixing the lid body 200 to the bottle body 100.

[0058] As shown in Figures 1 and 2, in this embodiment, a freeze-drying groove 241 is provided on the first ring portion 240. Specifically, when a vial is used to contain freeze-dried drugs, the moisture of the freeze-dried drugs needs to evaporate during the freezing process. In the process of snapping and fixing the cover 200 to the bottle body 100, the snap-on protrusion 251 and the snap-on boss 120 abut and cooperate to limit the upward movement of the bottle mouth of the vial within a preset force, so that the vial is in a semi-closed state, and the moisture inside can evaporate through the freeze-drying groove 241. After all the moisture has evaporated, the mounting body 210 is pressed with a force greater than the preset force to completely compact the cover 200, so that the upper end surface of the bottle body 100 and the first sealing ring 260 abut against each other, thereby sealing the bottle mouth of the vial.

[0059] Example 2

[0060] As shown in Figures 3, 6, 8, 11, 15, 17, 22, and 25, this embodiment differs from Example 1 in that the second sealing structure 400 is a sealing portion 420 integrally injection-molded with the second fixing structure 600, and the second fixing structure 600 is no longer provided with a sunken portion 630. Specifically, by integrally injection-molding the sealing portion 420 and the second fixing structure 600, a reliable seal is achieved, minimizing contact between the stopper 230 and the drug. Furthermore, the sealing portion 420 can be made of plastic, which has good compatibility with the drug. Optionally, the second fixing structure 600 is a support edge 610 or a second clamping portion, and the sealing portion 420 and the support edge 610 are integrally injection-molded, or the sealing portion 420 and the end of the second clamping portion facing away from the bottle body 100 are integrally injection-molded.

[0061] Example 3

[0062] As shown in Figures 4, 9, 10, 12, 13, and 16, this embodiment differs from Example 1 in that the second sealing structure 400 is a second sealing film 410 welded to the end surface of the second fixing structure 600 facing the bottle body 100. Specifically, the second sealing film 410 prevents contact between the stopper 230 and the drug while also providing low puncture resistance, facilitating needle puncture. Optionally, the second fixing structure 600 may be a supporting edge 610 or a second clamping portion.

[0063] Example 4

[0064] As shown in Figures 5, 6, 11, 12, 14, 15, 16, 21, 22, 24, and 25, this embodiment differs from Example 1 in that the second fixing structure 600 is a second retaining portion 620 that is clamped and connected to the second end of the accommodating portion 220 and is used to support the second end of the rubber plug 230, and the second sealing structure 400 is disposed on the second fixing structure 600. Specifically, the rubber plug 230 is fixed by the clamping ring and the pressure edge 510, and the clamping ring is assembled and connected to the installation body 210, which simplifies the internal structure of the installation body 210 and reduces the difficulty of the process. Optionally, the second holding portion 620 is arranged in a clamping ring shape, and the second sealing structure 400 is a sealing portion 420 that is integrally injection-molded with the end of the second holding portion 620 facing away from the bottle body 100; or the second sealing structure 400 is a sealing portion 420 that is integrally injection-molded with the end of the second holding portion 620 facing the bottle body 100; or the second sealing structure 400 is a second sealing film 410 welded and attached to the end surface of the second holding portion 620 facing the bottle body 100.

[0065] Example 5

[0066] As shown in Figures 7, 8, and 9, this embodiment differs from Example 1 in that the first fixing structure 500 is a first retaining portion 520 that is clamped and connected to the first end of the accommodating portion 220 and is used to press against the first end of the rubber plug 230. The first sealing structure 300 is a first sealing membrane 310 welded and attached to the end surface of the retaining ring facing away from the bottle body 100. Specifically, the retaining ring and the supporting edge 610 cooperate to secure the rubber plug 230. The retaining ring and the mounting body 210 are assembled and connected, simplifying the external structure of the mounting body 210 and reducing the difficulty of the process. The first sealing membrane 310 and the sealing portion 420 cooperate to achieve sealing of the rubber plug 230.

[0067] Example 6

[0068] As shown in Figures 10-12, this embodiment differs from Example 1 in that the first sealing structure 300 is a foldable cap 320 integrally injection-molded with the pressing edge 510. Specifically, the foldable cap 320 is easily broken open to expose the rubber plug 230, thereby facilitating needle puncture.

[0069] Example 7

[0070] As shown in Figures 13 to 15, the difference between this embodiment and embodiment 1 is that the first sealing structure 300 is a pull ring 330 that is integrally injection-molded with the pressing edge 510. Specifically, the pull ring 330 is easy to break open to expose the rubber plug 230, thereby facilitating puncture by an injection needle.

[0071] Example 8

[0072] As shown in Figures 18, 20, and 23, this embodiment differs from Example 1 in that the inner wall substrate of the container 220 and the base of the plug 230 are bonded and compatible, a first sealing structure 300 is disposed on the first end of the container 220, and a second sealing structure 400 is disposed on the second end of the container 220. Specifically, the inner wall substrate of the container 220 and the base of the plug 230 are bonded and compatible, eliminating the need for an additional fixing structure for the plug 230, significantly reducing the manufacturing and processing difficulty of the lid 200. Optionally, the first end of the container 220 is disposed away from the bottle body 100, and the first sealing structure 300 is a first sealing membrane 310 welded to the first end of the container 220; or the first sealing structure 300 is a foldable cap 320 integrally injection-molded with the first end of the container 220; or the first sealing structure 300 is a pull ring 330 integrally injection-molded with the first end of the container 220. Optionally, the second end of the receiving portion 220 is disposed toward the bottle body 100, and the second sealing structure 400 is a second sealing film 410 welded to the second end of the receiving portion 220. It should be understood that the plug 230 and the receiving portion 220 are bonded and compatible using a double-injection molding process.

[0073] Example 9

[0074] As shown in Figures 17, 18, 21, 22, 24, and 25, this embodiment differs from Example 1 in that the inner wall base of the accommodating portion 220 and the base of the rubber plug 230 are adhesively bonded and compatible with each other. A first sealing structure 300 is disposed on the first end of the accommodating portion 220, and a second fixing structure 600 is disposed on the second end of the accommodating portion 220. A second sealing structure 400 is disposed on the second fixing structure 600. Specifically, the second fixing structure 600 supports the rubber plug 230 to prevent excessive puncture force during injection needle puncture, which could cause the rubber plug 230 to be pulled into the bottle body 100. Optionally, the second sealing structure 400 is a second sealing membrane 410 welded to the end surface of the second fixing structure 600 facing away from the bottle body 100; or the second sealing structure 400 is a sealing portion 420 integrally injection-molded with the second fixing structure 600. Optionally, the second fixing structure 600 is a supporting edge 610 or a second clamping portion.

[0075] The foregoing description is merely a preferred embodiment of the present invention and is not intended to limit the present invention. Those skilled in the art will readily appreciate that various modifications and variations of the present invention are possible. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of the present invention are intended to be within the scope of protection of the present invention.

Claims

1. A high-barrier double-sealed penicillin bottle, comprising a bottle body (100) for containing medicines and a cover body (200) for sealing the bottle mouth of the bottle body (100), characterized in that: The cover body (200) includes a mounting body (210), a receiving portion (220) arranged on the mounting body (210), a receiving cavity opened in the receiving portion (220), a rubber plug (230) arranged in the receiving cavity, a first sealing structure (300) arranged on the first end of the receiving portion (220) for sealing the first end of the receiving cavity, a second sealing structure (400) arranged on the second end of the receiving portion (220) for sealing the second end of the receiving cavity, a first ring portion (240) and a second ring portion (250) arranged at intervals along the radial direction on the mounting body (210), and a rubber plug (230) arranged on the first ring portion (240) and the second ring portion The first sealing ring (260) between the first ring portion (240) and the second ring portion (250) is used for sealing tightly with the upper end surface of the bottle body (100), the inner wall of the first ring portion (240) is used for sealing with the inner wall of the bottle body (100), the inner wall of the second ring portion (250) is used for clamping and connecting with the outer wall of the cover body (200), the outer wall of the bottle body (100) is provided with a sealing step (110) extending radially outward, the end of the second ring portion (250) away from the installation body (210) is provided with a second sealing ring (270) for elastically contacting and sealing with the sealing step (110), the outer wall of the cover body (200) is provided with a barrier layer 1, and the outer wall of the bottle body (100) is provided with a barrier layer 2.

2. The high barrier double-sealed vial according to claim 1, characterized in that: The rubber plug (230) is detachably arranged in the accommodating cavity. The cover body (200) further includes a first fixing structure (500) arranged on the first end of the accommodating portion (220) and a second fixing structure (600) arranged on the second end of the accommodating portion (220) for cooperating with the first fixing structure (500) to fix the rubber plug (230). The first sealing structure (300) is arranged on the first fixing structure (500), and the second sealing structure (400) is arranged on the second fixing structure (600).

3. The high barrier double-sealed vial according to claim 2, characterized in that: The first end of the accommodating portion (220) is arranged facing away from the bottle body (100), and the first fixing structure (500) is a pressing edge (510) bent and arranged on the first end of the accommodating portion (220) for pressing the first end of the rubber plug (230); or The first fixing structure (500) is a first clamping portion (520) that is clamped and connected to the first end of the accommodating portion (220) and is used to press the first end of the rubber plug (230).

4. The high barrier double-sealed vial according to claim 2, characterized in that: The second end of the accommodating portion (220) is arranged toward the bottle body (100), and the second fixing structure (600) is a supporting edge (610) integrally injection-molded with the second end of the accommodating portion (220) for supporting the second end of the rubber plug (230); or The second fixing structure (600) is a second clamping portion (620) that is clamped and connected to the second end of the accommodating portion (220) and is used to support the second end of the rubber plug (230).

5. The high barrier double-sealed vial according to claim 2, characterized in that: The second end of the accommodating portion (220) is arranged toward the bottle body (100), and a sinking portion (630) for increasing the distance between the rubber plug (230) and the second sealing structure (400) is arranged on the second fixing structure (600).

6. The high barrier double-sealed vial according to claim 1, characterized in that: The inner wall matrix of the accommodating portion (220) and the matrix of the rubber plug (230) are bonded and compatible with each other.

7. The high barrier double-sealed vial according to claim 1, characterized in that: The first end of the accommodating portion (220) is arranged facing away from the bottle body (100), and the first sealing structure (300) is a first sealing film (310), a foldable cap (320) or a pull ring (330).

8. The high barrier double-sealed vial according to claim 1, characterized in that: The second end of the accommodating portion (220) is arranged toward the bottle body (100), and the second sealing structure (400) is a second sealing film (410) or a sealing portion (420).

9. The high barrier double-sealed vial according to claim 1, characterized in that: The inner wall of the second ring portion (250) is provided with a clamping protrusion (251), and the outer wall of the bottle body (100) is provided with a clamping boss (120) that is clamped and matched with the clamping protrusion (251).

10. The high barrier double-sealed vial according to claim 1, characterized in that: A freeze-drying groove (241) is provided on the first ring portion (240).

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