Bioparticle capture method
The bioparticle capturing method using a lipid molecule-modified nucleic acid with a branched structure addresses the limitations of existing lipid molecule labeling by ensuring stable and sufficient labeling without requiring double-strand formation, enhancing assay applicability and reducing costs.
WO2025205014A1PCT designated stage Publication Date: 2025-10-02SONY GROUP CORP
Patent Information
- Application Number
- PCT/JP2025/009671
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-03-28
- Filing Date
- 2025-03-13
- Publication Date
- 2025-10-02
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Figure JP2025009671_02102025_PF_FP_ABST
Abstract
Provided is a novel cell capture method. The present technology provides a bioparticle capture method, etc., in which at least a capture step, for capturing a bioparticle having a lipid membrane using a lipid-molecule-modified nucleic acid having a branched structure and a plurality of modified lipid molecules, is performed, and the distance from a branch point of the branched structure to a hydroxyl group that binds a lipid molecule is 3 Å or more.
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Citation Information
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