Integrated puncture and perfusion catheter for perfusion of donor abdominal organs for transplantation
By designing an integrated puncture-perfusion catheter and utilizing a puncture-perfusion switching mechanism and pressure control components, the problems of puncture structure damage to blood vessels and perfusion tubing deviation were solved, thereby improving organ transplant survival rate and perfusion efficiency.
Patent Information
- Application Number
- PCT/CN2024/132351
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-07-16
- Filing Date
- 2024-11-15
- Publication Date
- 2026-01-22
Smart Images

Figure CN2024132351_22012026_PF_FP_ABST
Abstract
Description
An integrated puncture perfusion catheter for abdominal organ transplant donor perfusion TECHNICAL FIELD
[0001] The present application relates to the technical field of surgical instruments for organ transplant donors, in particular to an integrated puncture perfusion catheter for abdominal organ transplant donor perfusion. BACKGROUND
[0002] In the field of organ transplantation, after the transplanted organ is removed from the donor, a perfusion liquid circulation system needs to be established as soon as possible to completely remove the blood from the organ and then to actively support it. During the operation of removing the abdominal organ for transplantation, the doctor needs to completely remove the blood inside the organ, and at the same time, a perfusion liquid circulation needs to be established to ensure that the organ will not lose its activity due to ischemia.
[0003] When the existing abdominal donor organ is punctured and perfused, the puncture structure on the outer surface enters the blood vessels in the organ and easily damages the intima of the blood vessels, thereby reducing the survival rate of the donor organ after removal, and in the subsequent perfusion, the doctor needs to remove the puncture structure and then insert the perfusion pipeline, which easily causes the perfusion pipeline to deviate from the puncture port, resulting in waste of perfusion liquid.
[0004] Therefore, in view of the above, the present application provides an integrated puncture perfusion catheter for abdominal organ transplant donor perfusion to make up for and improve the shortcomings of the prior art. SUMMARY
[0005] To solve the above technical problems, the present application provides an integrated puncture perfusion catheter for abdominal organ transplant donor perfusion, which can freely switch between puncture and perfusion at the same position, can extract blood from the liquid storage cylinder under negative pressure at the same time, and can accelerate perfusion by transferring pressure to the perfusion liquid.
[0006] To achieve the above purpose, the technical solution adopted by the present application is as follows: an integrated puncture perfusion catheter for abdominal organ transplant donor perfusion, comprising a puncture cylinder, the puncture end of the puncture cylinder being fixedly connected with a liquid storage cylinder, the integrated puncture perfusion catheter for abdominal organ transplant donor perfusion comprising:
[0007] a puncture-perfusion switching mechanism, the puncture-perfusion switching mechanism being arranged at the center of the puncture cylinder, and the puncture-perfusion switching mechanism being used to freely switch between puncture and perfusion of the puncture cylinder at the same position;
[0008] a pressure control assembly, the pressure control assembly being arranged between the puncture cylinder and the liquid storage cylinder, and the pressure control assembly being used to extract blood from the liquid storage cylinder under negative pressure at the same time, and to accelerate perfusion by transferring pressure to the perfusion liquid.
[0009] As preferred, the pricking and irrigating switching mechanism comprises a servo motor fixedly connected to the inner wall of the pricking cylinder, and the output end of the servo motor is fixedly connected with a gear disc.
[0010] As preferred, the pricking and irrigating switching mechanism further comprises a first rack and a second rack symmetrically and slidingly connected to the inner wall of the pricking cylinder, the first rack and the second rack are respectively engaged with the gear disc, one end of the first rack close to the liquid storage cylinder is fixedly connected with a support rod, the end of the support rod away from the first rack is fixedly connected with a pricking tip, one end of the second rack close to the liquid storage cylinder is fixedly connected with a support pipe, and the outer surface of the support pipe is fixedly connected with a blood blocking pad.
[0011] As preferred, a guide piece is arranged between the first rack and the support rod, the guide piece comprises a supply pipe fixedly connected to the first rack, the inner bottom surface of the supply pipe is fixedly connected with a spring, and the inner wall of the supply pipe is slidingly connected with a moving rod.
[0012] As preferred, the guide piece further comprises a guide frame fixedly connected to the first rack, the outer surface of the moving rod is rotatably connected with a moving roller, the moving roller is slidingly connected with the guide frame, and the end of the moving rod away from the supply pipe is fixedly connected with the support rod.
[0013] As preferred, a guide piece is arranged between the second rack and the support pipe, one end of the second rack close to the liquid storage cylinder is respectively fixedly connected with the supply pipe and the guide frame, and the end of the moving rod away from the supply pipe is fixedly connected with the support pipe.
[0014] As preferred, the inner wall of the liquid storage cylinder is fixedly connected with a liquid blocking pipe, the liquid blocking pipe is in communication with the pricking cylinder, and a liquid inlet hole is formed in the liquid storage cylinder.
[0015] As preferred, the liquid storage cylinder is in U shape, a supply and removal hole is formed in the center of the liquid storage cylinder, and the diameter of the supply and removal hole is greater than the diameter of the pricking tip.
[0016] As preferred, the pressure control assembly comprises a pressure adjusting cylinder fixedly connected to the outer surface of the pricking cylinder, one end of the pressure adjusting cylinder is in communication with a liquid discharge pipe, the liquid discharge pipe is in communication with the support pipe, and the other end of the pressure adjusting cylinder is in communication with a liquid suction pipe.
[0017] As preferred, a piston sheet is slidingly connected to the inner wall of the pressure adjusting cylinder, a magnetic ring is slidingly connected to the outer surface of the pressure adjusting cylinder, and the magnetic ring is magnetically connected with the piston sheet.
[0018] Compared with the prior art, the present application has the following advantages:
[0019] The first rack and the second rack and the guide piece cooperate, the rotation of the gear plate is used, the first rack and the second rack slide in the opposite direction of the puncture cylinder, the first rack carries the puncture sharp head to puncture the blood vessel in the organ through the guide piece, then the rotation of the gear plate makes the puncture sharp head move reversely to avoid the damage of the puncture sharp head to the blood vessel, the survival rate of the organ is improved, the second rack carries the support pipe through the guide piece and moves to the perfusion position, the support pipe replaces the puncture position of the puncture sharp head, the perfusion pipe is prevented from deviating from the puncture port, and the use cost of the perfusion liquid is saved;
[0020] The liquid blocking pipe and the liquid inlet hole cooperate, the blood splashed by the punctured blood vessel is collected through the liquid inlet hole, the blood splashed by the blood vessel enters the liquid storage cylinder, the blood in the liquid storage cylinder is blocked by the liquid blocking pipe, the blood is isolated from the puncture sharp head in the supply removal hole, on the one hand, the puncture sharp head is prevented from being soaked in the blood, and on the other hand, the cavity formed between the liquid blocking pipe and the liquid storage cylinder is used to collect the splashed blood;
[0021] The pressure adjusting cylinder and the magnetic ring cooperate, the perfusion liquid is stored in the liquid discharge cavity formed between the piston sheet and the pressure adjusting cylinder, the magnetic ring is actuated, the piston sheet is carried by the magnetic ring to extrude the perfusion liquid, the perfusion liquid is injected into the puncture position through the liquid discharge pipe and the support pipe, the movement of the piston sheet also extracts the blood stored in the liquid storage cylinder through the liquid extraction pipe, the blood in the liquid storage cylinder enters the liquid storage cavity formed between the piston sheet and the pressure adjusting cylinder, and the device is used for accelerating the injection of the perfusion liquid and the storage of the blood. BRIEF DESCRIPTION OF DRAWINGS
[0022] Fig. 1 is a schematic diagram of the overall structure of a preferred embodiment of the present application;
[0023] Fig. 2 is a schematic diagram of the overall structure of the present application;
[0024] Fig. 3 is a schematic diagram of the structure of the enlarged portion A in Fig. 2 of the present application;
[0025] Fig. 4 is a schematic diagram of the structure of the puncture sharp head moving towards the liquid blocking pipe of the present application;
[0026] Fig. 5 is a schematic diagram of the structure of the enlarged portion B in Fig. 4 of the present application;
[0027] Fig. 6 is a schematic diagram of the structure of the blood blocking pad moving towards the liquid blocking pipe of the present application;
[0028] Fig. 7 is a schematic diagram of the structure of the enlarged portion C in Fig. 6 of the present application;
[0029] Figure 8 is a schematic diagram of a moving rod and a tube splitting structure shown in the application.
[0030] The figure marks are: 1, puncture cylinder; 2, liquid storage cylinder; 3, puncture and infusion switching mechanism; 4, pressure control assembly; 5, liquid blocking pipe; 6, liquid inlet hole; 31, servo motor; 32, gear plate; 33, first rack; 34, guide; 35, support rod; 36, puncture tip; 37, second rack; 38, support pipe; 39, blood blocking pad; 41, pressure adjusting cylinder; 42, drainage pipe; 43, liquid suction pipe; 44, piston sheet; 45, magnetic ring; 341, tube; 342, guide frame; 343, spring; 344, moving roller; 345, moving rod. DETAILED DESCRIPTION
[0031] The technical solutions in the embodiments of the application will be described clearly and completely below with reference to the drawings in the embodiments of the application. Obviously, the described embodiments are only part of the embodiments of the application, rather than all the embodiments of the application. Based on the embodiments in the application, all other embodiments obtained by a person of ordinary skill in the art without creative work fall within the protection scope of the application.
[0032] Embodiments of the application
[0033] Please refer to figures 1 to 8, a kind of for abdominal organ transplantation donor perfusion integrated puncture perfusion catheter, including puncture cylinder 1, puncture cylinder 1 puncture end fixedly connected with liquid storage cylinder 2, a kind of for abdominal organ transplantation donor perfusion integrated puncture perfusion catheter includes:
[0034] puncture and infusion switching mechanism 3, puncture and infusion switching mechanism 3 is arranged at the center of puncture cylinder 1, and puncture and infusion switching mechanism 3 is used for free switching puncture and infusion of puncture cylinder 1 in the same position;
[0035] pressure control assembly 4, pressure control assembly 4 is arranged between puncture cylinder 1 and liquid storage cylinder 2, and pressure control assembly 4 is used for negative pressure extraction of blood in liquid storage cylinder 2 while, pressure is input to perfusion liquid and accelerates infusion;
[0036] puncture and infusion switching mechanism 3 includes servo motor 31 fixedly connected to the inner wall of puncture cylinder 1, and the output end of servo motor 31 is fixedly connected with gear plate 32;
[0037] The pricking and perfusing switching mechanism 3 further comprises a first rack 33 and a second rack 37 symmetrically and slidably connected to the inner wall of the pricking cylinder 1, the first rack 33 and the second rack 37 are respectively matched with the gear disc 32, and the first rack 33 is fixedly connected with a support rod 35 at one end close to the liquid storage cylinder 2, the end of the support rod 35 away from the first rack 33 is fixedly connected with a pricking sharp 36, and the second rack 37 is fixedly connected with a support pipe 38 at one end close to the liquid storage cylinder 2, and the outer surface of the support pipe 38 is fixedly connected with a blood blocking pad 39;
[0038] A guide 34 is arranged between the first rack 33 and the support rod 35, the guide 34 comprises a moving pipe 341 fixedly connected to the first rack 33, the inner bottom surface of the moving pipe 341 is fixedly connected with a spring 343, and the inner wall of the moving pipe 341 is slidably connected with a moving rod 345;
[0039] The guide 34 further comprises a guide frame 342 fixedly connected to the first rack 33, the outer surface of the moving rod 345 is rotatably connected with a moving roller 344, the moving roller 344 is slidably connected with the guide frame 342, and the end of the moving rod 345 away from the moving pipe 341 is fixedly connected with the support rod 35;
[0040] A guide 34 is arranged between the first rack 33 and the support rod 35, the guide 34 comprises a moving pipe 341 fixedly connected to the first rack 33, the inner bottom surface of the moving pipe 341 is fixedly connected with a spring 343, and the inner wall of the moving pipe 341 is slidably connected with a moving rod 345;
[0041] By the cooperation of the first rack 33, the second rack 37 and the guide 34, the rotation of the gear disc 32 can be used to control the first rack 33 and the second rack 37 to slide in opposite directions along the pricking cylinder 1, the first rack 33 carries the pricking sharp 36 to pierce the blood vessel in the organ through the guide 34, then the rotation of the gear disc 32 makes the first rack 33 move backward to avoid the pricking sharp 36 remaining in the blood vessel, so as to avoid damaging the inner membrane of the blood vessel and improve the survival rate of the organ, the second rack 37 carries the support pipe 38 to move towards the perfusion position through the guide 34, and the support pipe 38 replaces the pricking position of the pricking sharp 36, so as to avoid the perfusion pipeline deviating from the pricking hole and save the use cost of the perfusion liquid.
[0042] As shown in FIGS. 5 and 7, the inner wall of the liquid storage cylinder 2 is fixedly connected with a liquid blocking pipe 5, the liquid blocking pipe 5 is communicated with the pricking cylinder 1, and the liquid storage cylinder 2 is provided with a liquid inlet hole 6;
[0043] The liquid storage cylinder 2 is in a U shape, a moving hole is formed at the center of the liquid storage cylinder 2, and the diameter of the moving hole is greater than that of the pricking sharp 36;
[0044] Adopting the above scheme: through the cooperation of the liquid blocking pipe 5 and the liquid inlet hole 6, the blood splashed by the punctured blood vessel can be collected by the liquid inlet hole 6, so that the blood splashed by the blood vessel enters the liquid storage cylinder 2, and the liquid blocking pipe 5 blocks the blood entering the liquid storage cylinder 2, so that the blood is isolated from the puncture sharp 36 passing through the supply hole. On the one hand, the puncture sharp 36 is prevented from being immersed in the blood, and on the other hand, the cavity formed between the liquid blocking pipe 5 and the liquid storage cylinder 2 is used to collect the splashed blood.
[0045] Please refer to FIG. 1 to FIG. 4, the pressure control assembly 4 includes a pressure regulating cylinder 41 fixedly connected to the outer surface of the puncture cylinder body 1, one end of the pressure regulating cylinder 41 is communicated with a liquid discharge pipe 42, and the liquid discharge pipe 42 is communicated with the support pipe 38, the other end of the pressure regulating cylinder 41 is communicated with a liquid suction pipe 43;
[0046] The inner wall of the pressure regulating cylinder 41 is slidably connected with a piston sheet 44, and the outer surface of the pressure regulating cylinder 41 is slidably connected with a magnetic ring 45, and the magnetic ring 45 is magnetically connected with the piston sheet 44;
[0047] Adopting the above scheme: through the cooperation of the pressure regulating cylinder 41 and the magnetic ring 45, the perfusion liquid can be stored between the piston sheet 44 and the pressure regulating cylinder 41, and the magnetic ring 45 is actuated, and the piston sheet 44 is carried by the magnetic ring 45 to extrude the perfusion liquid, so that the perfusion liquid is injected into the puncture position through the liquid discharge pipe 42 and the support pipe 38. The movement of the piston sheet 44 also extracts the blood stored in the liquid storage cylinder 2 through the liquid suction pipe 43, so that the blood in the liquid storage cylinder 2 enters the storage cavity formed between the piston sheet 44 and the pressure regulating cylinder 41, which is beneficial to the device to accelerate the injection of perfusion liquid while extracting blood for storage.
[0048] Supplementary note: The pressure regulating cylinder 41 is divided into a storage cavity and a liquid discharge cavity by the piston sheet 44, the storage cavity is used to store the blood entering the liquid storage cylinder 2, and the liquid discharge cavity is used to inject the perfusion liquid;
[0049] The guide frame 342 is L-shaped, and the guide frame 342 is used for guiding rolling of the moving roller 344 in the guide piece 34, that is, after the moving roller 344 moves along the L-shaped guide frame 342, the moving roller 344 carries the moving rod 345 and moves away from the moving pipe 341, so that the spring 343 is contracted by the pulling of the moving rod 345, and the moving rod 345 also carries the support rod 35 or the support pipe 38 to move to the center of the liquid storage cylinder 2; after the moving roller 344 is separated from the guide frame 342, the spring 343 is reset, so that the moving rod 345 moves towards the inside of the moving pipe 341, and the moving rod 345 also carries the support rod 35 or the support pipe 38 to move to avoid the center of the liquid storage cylinder 2, so that the support pipe 38 avoids the support rod 35 when the support rod 35 moves towards the center of the liquid storage cylinder 2, and the support rod 35 avoids the support pipe 38 when the support pipe 38 moves towards the center of the liquid storage cylinder 2;
[0050] The liquid blocking pipe 5 and the liquid storage cylinder 2 form a storage cavity, and the storage cavity is used for storing blood flowing into the liquid storage cylinder 2 through the liquid inlet hole 6.
[0051] The working principle and use process of the application are as follows:
[0052] Preparation: the staff first injects perfusion liquid into the liquid discharge cavity formed between the piston sheet 44 and the liquid discharge pipe 42 in the pressure adjusting cylinder 41, and holds the puncture cylinder body 1, so that the puncture cylinder body 1 carries the liquid storage cylinder 2 and is aligned with the blood vessel in the organ;
[0053] Then, the staff controls the rotating direction of the gear plate 32 through the servo motor 31, so that the puncture and perfusion switching mechanism 3 is in the puncture state and the perfusion state, and the working process of the puncture and perfusion switching mechanism 3 is mainly described from the puncture state and the perfusion state for convenience of description and understanding:
[0054] In the puncture state: the gear plate 32 rotates clockwise, the first rack 33 and the second rack 37 are respectively matched with the gear plate 32, the first rack 33 and the second rack 37 are slidingly connected to the inner wall of the puncture cylinder body 1, the first rack 33 rotates with the gear plate 32 and moves towards the liquid storage cylinder 2, and the second rack 37 rotates with the gear plate 32 and moves in the opposite direction of the first rack 33, and since the first rack 33 is fixedly connected with the support rod 35 through the guide piece 34, the support rod 35 is fixedly connected with the puncture sharp head 36, the moving roller 344 in the guide piece 34 rolls along the guide frame 342, the moving rod 345 pulls and compresses the spring 343 to be contracted, so that the puncture sharp head 36 moves to the center of the puncture cylinder body 1, and the puncture sharp head 36 punctures the blood vessel in the organ along with the movement of the first rack 33;
[0055] In perfusion state: from the above working process, the gear plate 32 rotates anticlockwise, which makes the first rack 33 rotate with the gear plate 32 and move towards the direction away from the liquid storage cylinder 2, while the second rack 37 rotates with the gear plate 32 and moves towards the direction of the liquid storage cylinder 2, the movement of the first rack 33 links the puncture tip 36 and separates from the contact position of the blood vessel in the organ, while the movement of the second rack 37 replaces the position of the puncture tip 36;
[0056] Then, the staff member holds the magnetic ring 45 and moves it towards the direction away from the liquid storage cylinder 2, at this time, the magnetic ring 45 carries the piston sheet 44 magnetically connected therewith and moves, which makes the piston sheet 44 press the perfusion liquid in the drainage cavity, and makes the perfusion liquid flow through the pressure regulating cylinder 41-drainage pipe 42-supporting pipe 38 in turn and inject into the puncture site, at the same time, the movement of the piston sheet 44 extracts the blood stored in the liquid storage cylinder 2 through the suction pipe 43.
[0057] It is to be noted that the relative terms such as first and second, etc. are used herein only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply that there is any such actual relationship or order between these entities or operations. Moreover, the terms "include", "contain" or any other variants thereof are intended to cover non-exclusive inclusion, so that the process, method, article or equipment including a series of elements not only includes those elements, but also includes other elements not explicitly listed or inherent to such process, method, article or equipment.
[0058] Although the embodiments of the present application have been shown and described, it is to be understood that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present application, and the scope of the present application is defined by the appended claims and their equivalents.
Claims
1. An integrated puncture perfusion catheter for abdominal organ transplantation donor perfusion, comprising a puncture barrel (1), a liquid storage barrel (2) is fixedly connected to the puncture end of the puncture barrel (1), characterized in that, The integrated puncture perfusion catheter for abdominal organ transplant donor perfusion comprises: The puncture-perfusion switching mechanism (3) is arranged at the center of the puncture barrel (1) and is used for freely switching the puncture and perfusion of the puncture barrel (1) at the same position. The pressure control assembly (4) is arranged between the puncture barrel (1) and the liquid storage barrel (2) and is used for extracting blood in the liquid storage barrel (2) under negative pressure while accelerating perfusion by pressure transmission to the perfusion liquid.
2. The integrated puncture and perfusion catheter for perfusion of an abdominal organ transplant donor of claim 1, wherein, The puncture-perfusion switching mechanism (3) comprises a servo motor (31) fixedly connected to the inner wall of the puncture barrel (1), and the output end of the servo motor (31) is fixedly connected with a gear disc (32).
3. The integrated puncture and perfusion catheter for perfusion of an abdominal organ transplant donor of claim 2, wherein, The puncture-perfusion switching mechanism (3) further comprises a first rack (33) and a second rack (37) symmetrically and slidingly connected to the inner wall of the puncture barrel (1), the first rack (33) and the second rack (37) are respectively matched with the gear disc (32), one end of the first rack (33) close to the liquid storage barrel (2) is fixedly connected with a support rod (35), the end of the support rod (35) away from the first rack (33) is fixedly connected with a puncture tip (36), one end of the second rack (37) close to the liquid storage barrel (2) is fixedly connected with a support tube (38), and the outer surface of the support tube (38) is fixedly connected with a blood blocking pad (39).
4. The integrated puncture and perfusion catheter for perfusion of an abdominal organ transplant donor of claim 3, wherein, A guide piece (34) is arranged between the first rack (33) and the support rod (35), the guide piece (34) comprises a moving tube (341) fixedly connected to the first rack (33), the inner bottom surface of the moving tube (341) is fixedly connected with a spring (343), and the inner wall of the moving tube (341) is slidingly connected with a moving rod (345).
5. The integrated puncture and perfusion catheter for perfusion of an abdominal organ transplant donor of claim 4, wherein, The guide piece (34) further comprises a guide frame (342) fixedly connected to the first rack (33), the outer surface of the moving rod (345) is rotatably connected with a moving roller (344), the moving roller (344) is slidingly connected with the guide frame (342), and the end of the moving rod (345) away from the moving tube (341) is fixedly connected with the support rod (35).
6. The integrated puncture and perfusion catheter for perfusion of an abdominal organ transplant donor of claim 5, wherein, A guide piece (34) is arranged between the second rack (37) and the support tube (38), one end of the second rack (37) close to the liquid storage barrel (2) is fixedly connected with the moving tube (341) and the guide frame (342) respectively, and the end of the moving rod (345) away from the moving tube (341) is fixedly connected with the support tube (38).
7. The integrated puncture and perfusion catheter for perfusion of an abdominal organ transplant donor of claim 1, wherein, The inner wall of the liquid storage barrel (2) is fixedly connected with a liquid blocking tube (5), the liquid blocking tube (5) is communicated with the puncture barrel (1), and a liquid inlet hole (6) is formed in the liquid storage barrel (2).
8. The integrated puncture and perfusion catheter for perfusion of an abdominal organ transplant donor of claim 7, wherein, The liquid storage barrel (2) is in a U shape, a moving-through hole is formed at the center of the liquid storage barrel (2), and the diameter of the moving-through hole is greater than the diameter of the puncture tip (36).
9. The integrated puncture and perfusion catheter for perfusion of an abdominal organ transplant donor of claim 1, wherein, The pressure control assembly (4) comprises a pressure adjusting cylinder (41) fixedly connected to the outer surface of the puncture cylinder (1), one end of the pressure adjusting cylinder (41) is communicated with a liquid discharge pipe (42), the liquid discharge pipe (42) is communicated with the support pipe (38), and the other end of the pressure adjusting cylinder (41) is communicated with a liquid suction pipe (43).
10. The integrated puncture and perfusion catheter for perfusion of an abdominal organ transplant donor of claim 9, wherein, A piston sheet (44) is slidably connected to the inner wall of the pressure adjusting cylinder (41), a magnetic ring (45) is slidably connected to the outer surface of the pressure adjusting cylinder (41), and the magnetic ring (45) is magnetically connected with the piston sheet (44).
Citation Information
Patent Citations
Piercing pin for an infusion system
CA2223486A1
Puncture cannula and perfusion catheter for abdominal organ transplantation donor perfusion
CN112998822A
Integrated puncture perfusion catheter for donor perfusion in abdominal organ transplantation
CN115316375A
Integrated puncture perfusion catheter for donor perfusion in abdominal organ transplantation
CN118830538A