System and method for enriching and cleaning fat matrix components, and method for preparing fat matrix components

Abstract

Disclosed is a system for enriching and cleaning fat matrix components, which comprises: a first transmission channel from a buffer accommodating container (3) to a fat treatment structure (1), which is constructed by a third output pipeline (31), a main pipeline (5), and a first input pipeline (12); a second transmission channel from the fat treatment structure (1) to a waste liquid collection container (4), which is constructed by a first output pipeline (11), the main pipeline (5), and a third input pipeline (41); a third transmission channel from the fat treatment structure (1) to a centrifugal enrichment structure (2), which is constructed by the first output pipeline (11), the main pipeline (5), and a second input pipeline (22); a fourth transmission channel from the centrifugal enrichment structure (2) to the waste liquid collection container (4), which is constructed by a second output pipeline (21), the main pipeline (5), and the third input pipeline (41); and a fifth transmission channel from the buffer accommodating container (3) to the centrifugal enrichment structure (2), which is constructed by the third output pipeline (31), the main pipeline (5), and the second input pipeline (22). The system for enriching and cleaning fat matrix components can use simply one power pump (7) to complete the transmission of all channels.

Description

A system and method for enriching and cleaning fatty acid matrix components, and a method for preparing fatty acid matrix components. Technical Field

[0001] This invention belongs to the field of medical device technology, and particularly relates to devices related to the adipose matrix, specifically a system for enriching and cleaning adipose matrix components. This application also relates to a method for enriching and cleaning adipose matrix components using the aforementioned system. Furthermore, this application relates to a method for preparing adipose matrix components. Background Technology

[0002] Adipose-derived matrix components (ADRCs) contain cells unique to adipose tissue, such as smooth muscle cells, stromal cells, endothelial cells, and hematopoietic cells, which contribute to tissue repair. They also contain cellular and non-cellular components that regulate immunity and fibrosis. Physicians and scientists have demonstrated that the matrix components in adipose tissue have important functions such as promoting angiogenesis, regulating immunity, and resisting fibrosis. Adipose tissue can be obtained through a simple liposuction procedure; the technique is mature and minimally invasive, making it suitable for repairing tissue damage after surgery for many refractory diseases. Using mixtures of these adipose-derived matrix components with autologous fat can avoid the rejection and infection problems associated with artificial grafts, helping clinicians better address major clinical problems that traditional grafts cannot solve.

[0003] Therefore, effectively and rapidly obtaining autologous adipose matrix components is a technical problem that needs to be solved in clinical practice. Existing technology 202211090467.0 discloses a tubing system and a system for processing fat and adipose matrix components, but the enrichment of adipose matrix components involves numerous pathways. How to effectively set up the tubing to ensure smooth passage is a problem that needs to be solved in the extraction of adipose matrix components. Summary of the Invention

[0004] Currently, autologous human fat is typically used for processing. Fat is lysed to obtain adipose matrix components, which are then transferred to a centrifuge chamber for enrichment. The adipose matrix cells are then washed within the centrifuge chamber. Finally, the washed adipose matrix components can be used directly or mixed with adipose tissue, or collected for later use. This process involves buffer transport pathways during fat lysis (from the buffer container to the fat processing structure); waste liquid transport pathways after fat lysis (from the fat processing structure to the waste liquid collection container); adipose matrix transport pathway for transporting the adipose matrix components from the fat processing structure to the centrifugal enrichment structure before enrichment; waste liquid transport pathways after fat enrichment (from the centrifugal enrichment structure to the waste liquid collection container); and buffer transport pathways during the washing process (from the buffer container to the centrifugal enrichment structure). Each transport pathway involves multiple connections. A key characteristic of these pathways is that they are not connected simultaneously. Therefore, a system for enriching and washing the adipose matrix, incorporating tubing, needs to be designed. The principle is to use a minimal number of tubing components combined with a single power pump to complete the transport of all components.

[0005] This application also discloses a method for enriching and cleaning fatty matrix components.

[0006] This application also discloses a method for preparing adipose matrix components.

[0007] To achieve the above objectives, this application adopts the following technical solution:

[0008] A system for enriching and cleaning fatty acid matrix components includes: a fatty acid processing structure, a centrifugal enrichment structure, a buffer solution container, a main pipeline, a power pump, and a clamp valve; the fatty acid processing structure is connected to an output pipeline 1 for liquid output from the fatty acid processing structure and an input pipeline 1 for liquid input to the fatty acid processing structure. The centrifugal enrichment structure is connected to an output pipeline 2 for liquid output from the centrifugal enrichment structure and an input pipeline 2 for liquid input to the centrifugal enrichment structure. The buffer solution container is connected to an output pipeline 3 for liquid output from the buffer solution container. Waste liquid collection container: It is connected to an inlet pipe three for inputting waste liquid into the waste liquid collection container; Main pipeline: The main pipeline is connected to inlet pipes one to three and outlet pipes one to three respectively; Inlet pipe three and outlet pipe three are connected to the two edges of the main pipeline in the vertical direction; Inlet pipe one, outlet pipe one, inlet pipe two, and outlet pipe two are located between inlet pipe three and outlet pipe three; Inlet pipe one and outlet pipe one are located on one side of the main pipeline in the left-right direction, and inlet pipe two and outlet pipe two are located on the other side of the main pipeline in the left-right direction. Power pump: It is located outside the main pipeline, and is located between inlet pipe one and outlet pipe one, and also between inlet pipe two and outlet pipe two. Pinch valve: A pinch valve is installed on each of the inlet pipes one to three and the outlet pipes one to three.

[0009] The above setup ensures that the following transport pathways are established: buffer solution from the buffer container to the fat treatment structure; waste liquid from the fat treatment structure to the waste liquid collection container; fat matrix components from the fat treatment structure to the centrifugal enrichment structure; waste liquid from the centrifugal enrichment structure to the waste liquid collection container; and buffer solution from the buffer container to the centrifugal enrichment structure. Each transport pathway can be constructed through main pipelines and input or output pipelines connected to the corresponding structures. Simultaneously, the clamp valves of the input and output pipelines corresponding to the required individual transport pathways are opened, while the clamp valves of the input and output pipelines of other unnecessary transport pathways are closed. In this way, the power pump provides power to the constructed transport pathways, realizing the liquid transport within each individual transport pathway.

[0010] Furthermore, all pinch valves and power pumps are mounted on a platform. The platform is equipped with guide markers to facilitate pipeline installation. These markers are positioned between the pinch valves and include a main guide line and six branch guide lines corresponding to the pipelines. The pipelines consist of six lines: input lines one through three and output lines one through three.

[0011] Furthermore, at least one color-guided structure is set on the main guide line; at least one color-guided structure is set on the branch guide line, and corresponding color-matching structures are set on the main pipeline corresponding to the main guide line and the branch pipeline corresponding to the branch guide line; the color-guided structure is a color-marking block or a color-marking sticker set on the main guide line and the branch guide line, and the color-matching structure is a color-marking ring set on the main pipeline and the branch pipeline, with the color-marking ring sleeved on the outside of the pipeline.

[0012] The beneficial effects of this invention are as follows:

[0013] Through effective pipeline layout and setup, and based on the principle of time separation, by setting up only one power pump to provide power to the five transmission channels at different times, the enrichment and cleaning of the fat matrix components are completed in chronological order. This setup is reasonably designed and greatly reduces the space requirements of the equipment.

[0014] By placing the clamp valve and the power pump on the same platform, the complexity of setting up each structure can be greatly reduced, and the piping setup is also simpler.

[0015] By setting up guide markers on the platform, and setting at least one color guide structure on the main guide line and at least one color guide structure on the branch guide line, and setting color matching structures on the corresponding main pipelines of the main guide line and the corresponding branch pipelines of the branch guide lines, the difficulty of pipeline installation can be greatly reduced, the accuracy of pipeline installation can be guaranteed, and the efficiency of pipeline installation can be greatly improved. Attached Figure Description

[0016] Figure 1 is a schematic diagram of the planar structure of the system with color matching structure in this application;

[0017] Figure 2 is a schematic diagram of the system of this application with one main pipeline and six branch pipelines, and the transmission path in the system is connected while the other paths are closed. The arrows indicate the direction of liquid transmission. The pinch valves without crosses are connected pipelines, and the pinch valves with crosses are closed pipelines.

[0018] Figure 3 is a schematic diagram of the system of this application with one main pipeline and six branch pipelines, and the transmission path two in the system is connected while the other paths are closed;

[0019] Figure 4 is a schematic diagram of the system of this application with one main pipeline and six branch pipelines, and the transmission path in the system is three-way connected while the other paths are closed;

[0020] Figure 5 is a schematic diagram of the system of this application with one main pipeline and six branch pipelines, and the transmission path in the system is connected in four directions while the other paths are closed.

[0021] Figure 6 is a schematic diagram of the system of this application with one main pipeline and six branch pipelines, and five transmission paths in the system are connected while the other paths are closed;

[0022] Figure 7 is a schematic diagram of the system structure of this application, which includes one main pipeline, six branch pipelines, and a pressure detection structure.

[0023] Figure 8 is a schematic diagram of the system structure of this application, which includes one main pipeline, six branch pipelines, a pressure detection structure, and a liquid injection head.

[0024] Figure 9 is a schematic diagram of the planar structure of the platform for setting up guidance signs in this application;

[0025] Figure 10 is a schematic diagram of the overall appearance of the centrifugal enrichment structure of this application;

[0026] Figure 11 is a schematic diagram of the internal structure of the centrifugal enrichment structure of this application;

[0027] Figure 12 is a schematic diagram of the structure of the heating plate installed in the bilge of this application;

[0028] Figure 13 is a three-dimensional cross-sectional schematic diagram of the first embodiment of the collection chamber of the transverse enrichment structure of this application;

[0029] Figure 14 is a three-dimensional cross-sectional schematic diagram of another embodiment of the collection chamber of the transverse enrichment structure of this application;

[0030] Figure 15 is a schematic structural diagram of one embodiment of the mounting plate of this application;

[0031] Figure 16 is a schematic structural diagram of one embodiment of the extrusion plate of this application;

[0032] Figure 17 is a schematic structural diagram of one embodiment when the mounting plate is provided with two sets of connecting valves;

[0033] Figure 18 is a schematic structural diagram of one embodiment of the host computer;

[0034] Figure 19 is a schematic diagram of one embodiment with the mounting plate in the mounting position;

[0035] Figure 20 is a schematic structural diagram of one embodiment of the first space and the second space of this application;

[0036] Figure 21 is a schematic structural diagram of one embodiment of the first branch and the second branch;

[0037] Figure 22 is a schematic structural diagram of one embodiment of the valve section in this application when it is located in the first space;

[0038] Figure 23 is a schematic structural diagram of one embodiment of the mounting plate in the working position in this application;

[0039] Figure 24 is a schematic structural diagram of one embodiment of the valve section in this application when it is located in the second space;

[0040] Figure 25 is a bottom view of a schematic embodiment of the hose in this application when it passes through both sides of the second space;

[0041] Figure 26 is a schematic structural diagram of one embodiment of the hose passing through the extrusion channel in this application;

[0042] Figure 27 is a schematic structural diagram of one embodiment of the mounting plate in this application when it is provided with a heating groove.

[0043] Explanation of main reference numerals: 1. Fat processing structure; 11. Output pipeline one; 12. Input pipeline one; 2. Centrifugal enrichment structure; 21. Output pipeline two; 22. Input line 2; 23. Centrifuge chamber; 24. Chamber cover; 25. Chamber bottom; 26. Temperature maintenance ring; 27. Longitudinal notch; 28. Heating plate; 2010. Main body of transverse enrichment structure; 2101. Outer shell; 2102. Central cavity; 220. Collection chamber; 2201. Collection cavity; 2202. Sampling channel; 2203. Mounting slot; 2204. Interface; 2301. Seal A; 2302. Seal B; 240. Sampler; 250. Magnetic column; 3. Buffer solution container; 31. Output line 3; 4. Waste liquid collection container; 41. Input line 3; 5. Main line; 6. Pinch valve; 7. Power pump; 8. Pressure detection structure; 9. Liquid addition and extraction head; 10. Setting platform ; 101. Mounting plate; 102. Working surface; 103. Pump connecting part; 104. Working port; 105. Extrusion plate; 106. Valve connecting part; 107. Mating port; 108. Guide rail mating part; 109. Pipeline channel; 110. Threaded hole; 201. Main unit; 202. First space; 203. Second space; 204. Power pump head; 206. Heating tank; 207. Heating unit; 208. First guide rail; 209. Second guide rail; 210. Pipeline mounting port; 211. Roller; 301. Moving part; 302. First pivot shaft; 303. First connecting rod; 304. Wrench; 305. Hook; 401. Main guide line; 402. Branch guide line; 403. Color guide structure. Detailed Implementation

[0044] Referring to Figures 1-6; a system for enriching and cleaning fatty matrix components, comprising:

[0045] A fat processing structure 1 is connected to an output pipe 11 that outputs liquid from the fat processing structure 1 and an input pipe 12 that inputs liquid into the fat processing structure 1.

[0046] A centrifugal enrichment structure 2 is connected to an output pipe 21 that outputs liquid from the centrifugal enrichment structure 2 and an input pipe 22 that inputs liquid into the centrifugal enrichment structure 2.

[0047] A buffer solution container 3 is connected to an output pipe 31 that outputs liquid from the buffer solution container 3.

[0048] A waste liquid collection container 4 is connected to an input pipe 3 41 that inputs waste liquid into the waste liquid collection container 4;

[0049] A main pipeline 5 is connected to input pipelines 12 to 3 and output pipelines 11 to 3 respectively; input pipeline 3 and output pipeline 31 are connected to the two edges of the main pipeline 5 in the vertical direction; input pipeline 12, output pipeline 11, input pipeline 22 and output pipeline 21 are located between input pipeline 3 and output pipeline 31; input pipeline 12 and output pipeline 11 are located on one side of the vertical axis of the main pipeline 5 in the left and right direction, and input pipeline 22 and output pipeline 21 are located on the other side of the vertical axis of the main pipeline 5 in the left and right direction.

[0050] A power pump 7 is located outside the main pipeline 5, between the input pipeline 12 and the output pipeline 11, and also between the input pipeline 22 and the output pipeline 21.

[0051] Pinch valve 6 is installed on each of the input pipelines 12 to 3 and input pipelines 12 to 3.

[0052] The first transmission path from the buffer container 3 to the fat processing structure 1 is constructed through the output pipe 31, the main pipe 5 and the input pipe 12.

[0053] The second transmission path from the fat processing structure 1 to the waste liquid collection container 4 is constructed through the output pipeline 11, the main pipeline 5 and the input pipeline 3.

[0054] The third transmission path from the fat processing structure 1 to the centrifugal enrichment structure 2 is constructed through the output pipeline 11, the main pipeline 5 and the input pipeline 22.

[0055] The fourth transmission path from the centrifugal enrichment structure 2 to the waste liquid collection container 4 is constructed through the output pipeline 21, the main pipeline 5, and the input pipeline 3.

[0056] The fifth transmission path from the buffer container 3 to the centrifugal enrichment structure 2 is constructed through the third output pipe 31, the main pipe 5, and the second input pipe 22.

[0057] Each transmission path can be constructed one by one through the main pipeline 5 and the input or output pipelines connected to the corresponding structures. Simultaneously, the pinch valves 6 of the input and output pipelines corresponding to the required individual transmission path are opened, while the pinch valves 6 of the input and output pipelines of other unnecessary transmission paths are closed. This allows the power pump 7 to provide power to the constructed transmission path, realizing liquid transfer within a single transmission path. The above method effectively utilizes five different transmission paths.

[0058] A more preferred embodiment is as follows: Input pipe one and input pipe two are connected to main pipe 5 at the same longitudinal axis position; output pipe one and output pipe two are connected to main pipe 5 at the same longitudinal axis position; wherein input pipe one and input pipe two are closer to input pipe three; and output pipe one and output pipe two are closer to output pipe three. This arrangement ensures that the input pipe is located on one side of the power pump 7 and the output pipe is located on the other side of the power pump 7, ensuring that any input pipe and output pipe can be configured into the required transmission path.

[0059] Referring to Figures 1, 7, and 8; a more preferred embodiment is as follows: two pressure detection tubes and / or one liquid addition / extraction tube are connected and installed at the edge of the main pipeline 5 in the vertical direction; a pressure detection valve is installed on the outside of the pressure detection tube; and a liquid addition / extraction head 9 is installed on the liquid addition or extraction tube. Pressure detection valves are used to detect pressure within the pipeline to determine if there is any leakage; liquid is added to or extracted from the pipeline by inserting a syringe into the liquid addition / extraction head 9.

[0060] A more preferred embodiment is as follows: the main pipeline 5 is provided with three sections of flexible hose, and the output pipelines 11 to 3 and the input pipelines 12 to 3 are a complete section of flexible hose. The three sections of the main pipeline 5 are the first section, the second section, and the third section. The first end of the first section is provided with a two-way pipe 1, which connects the first section to the output pipeline 3. The second end of the first section is provided with a four-way pipe 1, which connects the first section, the second section, the input pipeline 1, and the input pipeline 2. The second end of the second section is provided with a four-way pipe 2, which connects the second section, the third section, the output pipeline 1, and the output pipeline 2. The second end of the third section is provided with a two-way pipe 2, which connects the third section to the output pipeline 31. The power pump 7 is located outside the second section. The segmented design facilitates the assembly of tubing, reducing the complexity of the integrated connection process for soft materials. Furthermore, because the tubing used for fat matrix enrichment and cleaning is made of special materials, if leakage occurs during the treatment of the same patient, a specific tubing can be addressed, avoiding the need to replace all tubing due to a problem with one tubing.

[0061] A more preferred embodiment is to replace two-way pipe one and two-way pipe two with three-way pipe one and three-way pipe two; add a pressure detection pipe to each two-way pipe, and install a pressure detection valve on the outside of the pressure detection pipe. The pressure inside the pipe is detected by setting the pressure detection valve, and the presence of leakage is determined by the pressure detection.

[0062] A more preferred embodiment is to replace the two-way pipe one or two-way pipe two with the three-way pipe one or three-way pipe two; add a liquid addition / extraction pipe to a two-way pipe, and install a liquid addition / extraction head 9 on the liquid addition or extraction pipe, and add liquid to the pipe or extract liquid from the pipe by inserting a syringe into the liquid addition / extraction head 9.

[0063] A more preferred embodiment is to replace the two-way pipe one or two-way pipe two with the four-way pipe one or four-way pipe two, and add a pressure detection pipe and a liquid addition / extraction pipe to each four-way pipe based on a two-way pipe; a pressure detection valve is installed on the outside of the pressure detection pipe; and a liquid addition / extraction head 9 is installed on the liquid addition or extraction pipe.

[0064] Referring to Figures 1 and 9; a more preferred embodiment is that all clamp valves 6 and power pumps 7 are mounted on a mounting platform 10; the platform is provided with guide markers for convenient pipeline installation, which are positioned between the clamp valves 6 and include a main guide line 401 and six branch guide lines 402 corresponding to the pipelines. Through the guiding effect of the main guide line 401 and the branch guide lines 402, each pipeline can be accurately positioned and pass through each clamp valve 6 to connect with the corresponding instrument structure.

[0065] A more preferred embodiment is as follows: at least one color-guided structure 403 is provided on the main guide line 401; at least one color-guided structure 403 is provided on the branch guide line 402, and corresponding color-matching structures are provided on the main pipeline 5 corresponding to the main guide line 401 and the branch pipeline corresponding to the branch guide line 402; the color-guided structure 403 is a color-marking block or a color-marking sticker provided on the main guide line and the branch guide line 402, and the color-matching structure is a color-marking ring provided on the main pipeline 5 and the branch pipeline, with the color-marking ring sleeved on the outside of the pipeline. By setting a color-guided structure 403 on the main guide line 401 and a color-guided structure 403 on the branch guide line 402, all pipelines can be quickly set to the accurate position, avoiding repeated matching by operators according to the relationship between each pipeline and connector. This setting method is simple to set and convenient to match.

[0066] A more preferred embodiment is as follows: two color-guided structures 403 are provided on the main guide line 401, and two color-guided structures 403 are provided on the branch guide line 402. The two color-guided structures 403 on the main guide line 401 are located between the first and third sections of the pipeline; the two color-guided structures 403 on the branch guide lines 402 are located on the branch guide lines 402 corresponding to the output pipeline 21 and input pipeline 22 connected to the centrifugal enrichment structure 2. The two color-guided structures 403 on the main and branch guide lines are of different colors; the two color-guided structures 403 on the branch guide lines 402 are also of different colors. This method improves recognition efficiency, allowing the pipeline setup to be completed by quickly finding a set of corresponding color-guided structures 403.

[0067] Alternatively, referring to Figure 9; two color-guided structures 403 are provided on the main guide line 401, and two color-guided structures 403 are provided on the branch guide line 402. The two color-guided structures 403 on the main guide line 401 are located between the first and third sections of the pipeline; the two color-guided structures 403 on the branch guide line 402 are located on the branch guide lines 402 corresponding to the output pipeline 11 and the input pipeline 12 connected to the fat processing structure 1. The two color-guided structures 403 on the main and branch guide lines are of different colors; the two color-guided structures 403 on the branch guide lines 402 are also of different colors.

[0068] Setting color-guided structures 403 on the branch guide line 402 corresponding to the middle branch pipeline and on the first and third sections of the main pipeline at both ends of the main pipeline 5 can effectively improve the efficiency of identification.

[0069] Referring to Figures 14-20, in a more specific embodiment, the platform includes a main unit and a mounting plate. The working surface 102 of the mounting plate 101 is provided with a valve connecting part 106 and a pump connecting part 103. Both the valve connecting part 106 and the pump connecting part 103 are provided with pipeline channels 109 for the main pipeline 5 to pass through. The valve connecting part 106 is provided with a mating port 107 for the clamping part of the clamping valve 6 to enter. The pump connecting part 103 is provided with a working port 104 for the roller 211 of the power pump head 204 to enter and a pressing plate 105 disposed in the working port 104 and capable of forming a pressing channel with the roller 211. The mating port 107 and the working port 103 are also provided with a valve connecting part 106 and a pump connecting part 103. 04 is connected to the pipeline channel 109. See Figure 14. The roller 211 can extend into the working port 104, and the shape of the working port 104 matches the rotation path formed by the roller 211 around the rotation axis of the power pump head 204. The roller 211 can rotate around the rotation axis in the working port 104. The main pipeline 5 can pass through the gap between the roller 211 and the extrusion plate 105. When the roller 211 rotates around the rotation axis, it will squeeze the main pipeline 5 between the roller 211 and the extrusion plate 105, thereby pumping the liquid in the main pipeline 5. The openings of the mating port 107 and the working port 104 have the same orientation. The pump unit 103 is also provided with a threaded hole 110. When the main pipeline 5 in the pipeline channel 109 passes through the working port 104 and the extrusion plate 105, the working port 104 is sealed with a screw that mates with the threaded hole 110 to prevent the main pipeline 5 from leaving the working port 104. Of course, there are other ways to fix the main pipeline 5 to the working port 104, such as snap-fit, which will not be described in detail here.

[0070] The main unit 201 and the mounting plate 101 are detachably connected; the openings of the mating port 107 and the working port 104 face a first direction, which is parallel to the working surface 102. The working surface 102 is provided with multiple valve connecting parts 106; the main unit 201 is provided with an instrument space, which includes a first space 202 and a second space 203. Referring to Figure 20, in one embodiment of this application, the instrument space is provided with three first spaces 202 and three second spaces 203. The three second spaces 203 are arranged sequentially along the first direction, with a first space 202 between two adjacent second spaces 203, and the remaining first space 202 located among the three second spaces. On one side of the starting position in the first direction, i.e. along the first direction, a first space 202, a second space 203, a first space 202, a second space 203, a first space 202, and a second space 203 are arranged in sequence; a power pump head 204 is provided in the second space 203 between the two second spaces 203, and multiple clamp valves 6 are provided in the other second spaces 203 respectively, and the pipe installation port 210 of the clamp valve 6 is oriented opposite to the first direction; the mounting plate 101 is provided with two sets of connecting valve parts 106 and a connecting pump part 103 located between the two sets of connecting valve parts 106, and the connecting valve parts 106 and the connecting pump part 103 are spaced apart in the first direction.

[0071] The main pipeline 5 passes through the pipeline channel 109 and the working port 104 and mating port 107 in the mounting plate 101. When the mounting plate 101 and the main unit 201 are connected, the connecting valve part 106 and the connecting pump part 103 are first inserted into the corresponding first space 202, as shown in Figures 20 and 22. The connecting pump part 103 and each group of connecting valve parts 106 are set in three corresponding first spaces 202. When the working surface 102 of the mounting plate 101 is fastened to the main unit 201 (see Figure 19), the mounting plate 101 is in the installation position relative to the main unit 201. When the mounting plate 101 moves in the first direction, the connecting pump part 103 and each group of connecting valve parts 106 move from the first space 202 and the second space 203, so that the mounting plate 101 reaches the working position. The positions are shown in Figures 23 to 26. The mating ports 107 of each connecting valve 106 are simultaneously connected to the respective pipe mounting ports 210. The main pipe 5 in the mating port 107 enters the pipe mounting port 210 of the pinch valve 6, thus enabling the pinch valve 6 to control the closure of the main pipe 5. Simultaneously, the roller 211 of the power pump head 204 enters the working port 104. The roller 211 and the extrusion plate 105 are spaced apart. The movement path of the roller 211 around the rotation axis and the extrusion plate 105 are spaced apart, forming an extrusion channel through which the main pipe 5 passes. When the roller 211 rotates around the rotation axis, it can extrude force on the main pipe 5, thus pumping liquid through the main pipe 5 under its own elasticity and the extrusion action of the roller 211.

[0072] The two sets of pinch valves 6 are located on both sides of the power pump to facilitate pipeline installation. See Figures 20 and 21. Each set of pinch valves 6 has three pinch valves 6. Output pipeline 11, input pipeline 12, and output pipeline 31 are respectively connected to the set of pinch valves 6 through a set of connecting valve parts 106. Output pipeline 21, input pipeline 22, and input pipeline 31 are respectively connected to the other set of pinch valves 6 through another set of connecting valve parts 106. The main pipeline 5 is located in the extrusion channel formed by the roller 211 and the extrusion plate 105. When the roller 211 rotates around the rotation axis, it can pump the liquid in input pipeline 12, input pipeline 22, and input pipeline 31 to output pipeline 11, output pipeline 21, and output pipeline 31. By controlling the state of different pinch valves 6, the opening and closing of different input and output pipelines can be controlled, thereby realizing the fluid entering different pipelines.

[0073] Those skilled in the art to which this application pertains will understand that the clamp valve 6 in this application can also be provided as a set, such that the set of clamp valves 6 is located at the inlet or outlet of the extrusion channel, so that the power pump head 204 can pump liquids from different sources, or pump liquids from the same source to different branches. Of course, other sets or other quantities of clamp valves 6 can also be provided, which will not be elaborated here.

[0074] Referring to Figure 20, the second space 203 is equipped with a power pump head 204 and multiple clamp valves 6. The first space 202 and the second space 203 are arranged sequentially along a first direction. The clamping part of the clamp valve 6 is provided with a pipe installation port 210, and the orientation of the pipe installation port 210 is opposite to the first direction. When the mounting plate 101 is connected to the main unit 201, the pump connecting part 103 and the valve connecting part 106 entering the first space 202 move along the first direction and finally enter the second space 203, so that the mating ports 107 of the multiple valve connecting parts 106 can simultaneously and respectively The system connects to multiple pipe installation ports 210. Simultaneously, the rollers 211 of the power pump head 204 enter the working port 104 and can squeeze the main pipeline 5 through the squeezing channel. Thus, the main pipeline 5 is installed in the accurate position through the mounting plate 101, so that the main pipeline 5 is connected to the clamp valve 6 and the power pump head. The mounting plate 101 can quickly install the main pipeline 5 with multiple branch pipelines into multiple clamp valves 6 and install the main pipeline 5 into the power pump head, which greatly improves the installation efficiency and ensures the accuracy of the installation of the main pipeline 5.

[0075] In a more specific embodiment, the power pump 7 is a peristaltic pump installed on the installation platform 10. The peristaltic pump can ensure that the main pipeline 5 is clamped on the peristaltic pump, and the installation is simple and convenient. The installation will not affect the shape of the pipeline and no liquid flows through the peristaltic pump.

[0076] Those skilled in the art to which this application pertains will understand that there are various ways to achieve a detachable connection between the mounting plate 101 and the host 201, such as snap-fit. In order to ensure that the mounting plate 101 can accurately connect the main pipeline 5 to the clamp valve 6 and the power pump, this application provides a technical solution.

[0077] In one embodiment of this application, the mounting plate 101 is provided with a guide rail mating part 108, as shown in Figures 1 to 3; the host 201 is provided with a first guide rail 208, as shown in Figure 18. The first guide rail 208 extends in the same direction as the first direction. The first guide rail 208 is provided with a guide rail notch at the installation position. The guide rail mating part 108 can enter the first guide rail 208 through the guide rail notch, as shown in Figure 19. The guide rail mating part 108 that enters the first guide rail 208 through the guide rail notch can move along the first guide rail 208 in the first direction to reach the working position, so that the mating port 107 is connected to the pipeline connection port, and the roller 211 can extend into the working port 104. At the same time, the first guide rail 208 fixes the mounting plate 101 to prevent the mounting plate 101 from leaving the host 201 in a direction perpendicular to the working surface 102. The first guide rail 208 ensures that the mating port 107 and the working port 104 are aligned with the pipe installation port 210 and the rotation path of the roller 211 of the clamp valve 6, respectively, so as to ensure that the main pipe 5 can be accurately and stably installed into the pipe installation port 210 and the squeezing channel, avoiding errors caused by manual positioning.

[0078] Furthermore, the main unit 201 is provided with a motion assembly, which includes a moving component 301 and a second guide rail 209 connected to the main unit 201. The second guide rail 209 extends in the same direction as the first direction. The moving component 301 is slidably connected to the second guide rail 209. The moving component 301 is provided with a locking structure that can be detachably connected to the mounting plate 101. Referring to Figure 5, the locking structure includes a hook 305, which is pivotally connected to the moving component 301, so that when the hook 305 rotates, it can hook onto or leave the mounting plate 101. Referring to Figures 19 and 23, the moving component 301... When the second guide rail 209 moves along the first direction, the moving part 301 pushes the mounting plate 101 along the first guide rail 208 in the first direction so that the mounting plate 101 reaches the working position; when the moving part 301 moves along the second guide rail 209 in the opposite direction to the first direction, the moving part 301 pulls the mounting plate 101 along the first guide rail 208 in the opposite direction to the first direction through the hook 305 so that the pipeline connection port leaves the mating port 107. Finally, the hook 305 is rotated, the hook 305 is disconnected from the mounting plate 101, and the mounting plate 101 can be removed from the first guide rail 208.

[0079] Of course, by adjusting the position of the moving part 301 relative to the mounting plate 101, the moving part 301 can also push the mounting plate 101 to move in the opposite direction to the first direction, and the moving part 301 can pull the mounting plate 101 to move in the first direction through the hook 305. This will not be elaborated further here.

[0080] Those skilled in the art to which this application pertains will understand that the locking structure in this application can also be other structures, such as a snap-fit ​​structure, which will not be elaborated here. The moving part 301 can drive the mounting plate 101 to move along the first direction and in the opposite direction to the first direction.

[0081] There are multiple ways to realize the movement of the moving component 301 along the second guide rail 209. For example, the moving component also includes a wrench 304, a first connecting rod 303, and a first pivot shaft 302. The wrench 304 is pivotally connected to the main unit 201 through the first pivot shaft 302. The middle part of the wrench 304 is connected to the moving component 301 through the first connecting rod 303. The two ends of the first connecting rod 303 are pivotally connected to the moving component 301 and the wrench 304, respectively. The distance from the handle of the wrench 304 to the connection point between the first connecting rod 303 and the wrench 304 is greater than the distance between the connection point between the first connecting rod 303 and the wrench 304 and the connection point between the first pivot shaft 302 and the wrench 304. Thus, the wrench 304 becomes a force-saving lever, so as to better drive the mounting plate 101 to move along the first guide rail 208 through the moving component 301, so as to better install and disassemble the main pipeline 5.

[0082] Referring to Figure 25, in one embodiment of this application, the rotating end face of the power pump head 204 is parallel to the working surface. In another embodiment of this application, the projection of the working port 104 on the working surface is arc-shaped. Referring to Figure 3, the rotation path of the roller 211 around the rotation axis of the pump head passes through the working port 104 and partially coincides with the extension direction of the working port 104. The roller 211 can extend into the working port 104. The roller 211 and the extrusion plate 105 work together to form an extrusion channel and extrude the main pipeline 5 in the extrusion channel.

[0083] By making the rotating end face of the power pump head 204 parallel to the working surface, the space occupied by the power pump head 204 in the direction perpendicular to the working surface 102 can be greatly reduced, which helps to reduce the height of the mounting plate 101.

[0084] Referring to Figure 26, in one embodiment of this application, the pipeline control and heating structure further includes a heating tank 206 and a heating unit 207 connected to the heating tank 206. The heating unit 207 can be a component such as a heating wire or heating tube. The heating unit 207 is located on the main unit 201 and can heat the working liquid in the heating tank 206. The location of the heating tank 206 is not fixed.

[0085] For example, heating tank 206 and heating unit 207 are provided in main unit 201, and first space 202 and second space 203 are provided in heating tank 206 (see Figures 18, 25-26). Heating unit 207 is provided in heating tank 206, so heating unit 207 can heat working liquid in heating tank 206. When mounting plate 101 is connected to main unit 201, main pipeline 5 can enter heating tank 206 under the action of pipeline channel 109, connecting pump 103 and connecting valve 106, and be immersed in working liquid in heating tank 206. Thus, working liquid performs water bath heating on main pipeline 5 to prevent fat coagulation.

[0086] The heating tank 206 can also be installed on the mounting plate 101. Referring to Figure 27, the main pipeline 5 connected to the mounting plate 101 passes through the heating tank 206. The heating unit 207 is installed on the main unit 201. The heating tank 206 is connected to the heating unit 207 through a heat conductor. The pipeline channel 109 passes through the heating tank 206. When the mounting plate 101 is connected to the main unit 201, the main pipeline 5 connected to the mounting plate 101 can be immersed in the working liquid heated by the heating unit 207, so that the liquid in the heating tank 206 can perform water bath heating on the main pipeline 5.

[0087] Of course, the heating unit 207 can also be installed on the outer wall of the heating tank 206. The outer wall of the heating tank 206 is made of a heat-conducting material, and the heating unit 207 heats the working liquid through the heating tank 206.

[0088] Alternatively, in one embodiment of this application, the host 201 is provided with a heating unit 207, and the mounting plate 101 is provided with a heat conductor. The heat conductor is connected to the pipeline channel 109. When the host 201 is connected to the mounting plate 101, the heating unit 207 is connected to the heat conductor and can directly heat the main pipeline 5 in the pipeline channel 109 through the heat conductor.

[0089] Of course, the heating unit and heating tank can be set up in other ways, which will not be elaborated here.

[0090] In one embodiment of this application, when the host 201 is provided with a heating unit 207 and a heating tank 206, the working surface 102 is perpendicular to the depth direction of the heating tank 206, the instrument space is located in the heating tank 206, and when the mounting plate 101 is connected to the host 201 and reaches the working position, the mounting plate 101 closes the communication between the heating tank 206 and the outside world, thereby reducing the heat loss of the working fluid.

[0091] In one embodiment of this application, the fat processing structure 1 is a processing tank or a processing bag; preferably, it is a fat processing tank, which is set on a shaking weighing structure. The processing tank is shaken by the shaking weighing structure, and the processing tank is weighed after the first step of processing to ensure that a sufficient amount of fat is processed, thereby ensuring that the fat matrix components obtained in the final enrichment are sufficient.

[0092] Referring to Figure 10-12; the centrifugal enrichment structure 2 is set inside the covered centrifuge chamber, and the output pipe 21 and the input pipe 22 extend into the underside of the cover of the centrifuge chamber and into the central axis pipe of the centrifugal enrichment structure 2; the centrifugal enrichment apparatus includes a transverse enrichment structure, and the central axis pipe is set in the middle of the transverse enrichment structure; the rotation of the centrifugal enrichment structure 2 will not cause the central axis pipe to rotate, and this setting can ensure the positional stability of the output pipe 21 and the input pipe 22 after they are connected. The central tube is rotatably connected to the transverse enrichment structure, and a sealing material is provided at the connection to maintain a leak-proof seal. Specifically, the sealing material is a material that does not deform with temperature. Alternatively, a temperature-maintaining structure is provided on the cover 24. This structure is a temperature-maintaining ring 26 extending from the center of the cover 24 and surrounding the central tube. The temperature-maintaining ring 26 has a longitudinal notch 27 for connecting the output tube and the input tube. A heating structure and a temperature control structure are provided inside the temperature-maintaining ring 26. Preferably, the wires of the temperature-maintaining structure are guided to the power supply position through the cover 24. Alternatively, a heating plate 28 is provided at the bottom 25 of the chamber to maintain the temperature of the entire centrifuge chamber 23. The heating plate 28 can be an annular plate arranged 360 degrees around the bottom of the chamber, and it is connected to a temperature control structure. These technical solutions effectively solve the leakage problem of centrifugal enrichment instruments. In particular, the design of the heating plate 28 at the bottom of the chamber achieves the goal by maintaining the temperature of the entire chamber. Furthermore, the constant temperature setting of the entire chamber also effectively maintains the activity of the fat matrix components within the chamber. Maintain a temperature range of 32-37℃.

[0093] Referring to Figure 13; the transverse centrifugal structure includes a transverse enrichment structure body 2010 and a collection chamber 220; the transverse enrichment structure body 2010 has an outer shell 2101 and a central cavity 2102 inside the outer shell 2101; the collection chamber 220 is connected to both ends of the outer shell 2101, and the collection cavity 2201 inside the collection chamber 220 is connected to the central cavity 2102; the collection chamber 220 and the transverse enrichment structure body 2010 are integrally formed, and the collection chamber 220 and the central cavity 2102 are always in communication; a sampling channel 2202 penetrating the collection chamber 220 is opened at the upper end of the collection cavity 2201, and a sealing structure is provided inside the sampling channel 2202; the sealing structure has two states: open and closed; when the sealing structure is in the open state, the collection cavity 2201 is connected to the outside; when the sealing structure is in the closed state, the collection cavity 2201 is cut off from the outside.

[0094] Referring to Figure 13, the sealing structure is an elastic seal A2301, which is inserted into the sampling channel 2202. The seal A2301 and the sampling channel 2202 are interference-fitted. The seal A2301 seals the sampling channel 2202 to prevent the target product from overflowing the collection chamber 2201 during centrifugation, and also isolates the outside world from the collection chamber 2201 during centrifugation. The collection chamber 2201 is closed only when the seal A2301 is inserted into the sampling channel 2202, thus cutting off the connection between the collection chamber 2201 and the outside world.

[0095] Referring to Figure 13, a sampler 240 is inserted inside the seal A2301, penetrating the seal A2301 and reaching the bottom of the collection chamber 2201. The sampler 240 is a slender tubular structure. One end of the sampler 240 is inserted into the collection chamber 2201 and contacts the fat cell matrix enriched in the collection chamber 2201. The fat cell matrix is ​​recovered or sampled by the negative pressure provided at the other end. After the sampler 240 is inserted into the seal A2301, the seal A2301 is in the open state, and the collection chamber 2201 is connected to the outside.

[0096] Referring to Figure 14, the sealing structure is a spherical seal B2302; the sampling channel 2202 has a mounting groove 2203 in the middle, and one end of the mounting groove 2203 coincides with the sampling channel 2202; a seal B2302 is provided inside the mounting groove 2203, the outer surface of which is in close contact with the inner wall of the mounting groove 2203, and the seal B2302 rolls along the mounting groove 2203; the diameter of the seal B2302 is larger than the diameter of the sampling channel 2202; one end of the mounting groove 2203 coincides with the sampling channel 2202, while the height of the other end of the mounting groove 2203 is lower than the height of the end that coincides with the sampling channel 2202, so that the seal B2302 is at the lower end of the mounting groove 2203 in its natural state. In centrifugal state, the seal B2302 is subjected to centrifugal force and slides from the lower end of the mounting groove 2203 to the end that overlaps with the sampling channel 2202. As above, when the seal B2302 is at the lower end of the mounting groove 2203, the sealing structure is in the open state, and the collection chamber 2201 is connected to the outside. At this time, the sampler 240 can be used to easily take out the enriched fat cell matrix from the collection chamber 2201. When the seal B2302 is at the end of the mounting groove 2203 that overlaps with the sampling channel 2202, the sealing structure is in the closed state, and the collection chamber 2201 is cut off from the outside. At this time, in centrifugal state, the sampling channel 2202 is automatically blocked, which can effectively prevent the target product from overflowing from the collection chamber 2201.

[0097] Referring to Figure 14, a magnetic column is fixedly connected to the other end of the mounting groove 2203; the sealing element B2302 is ferromagnetic; in another embodiment different from the above, the height of the other end of the mounting groove 2203 can be equal to or higher than the height of the end of the mounting groove 2203 that overlaps with the sampling channel 2202. The opening state of the sealing element B2302 is completed by the attraction of the magnetic column 250, and during centrifugation, the centrifugal force overcomes the attraction of the magnetic column 250 on the sealing element B2302. Compared with the above embodiment, control by the magnetic column 250 is more stable and also applicable to the case of the sampling channel 2202 being reversed.

[0098] As shown in Figure 13, the bottom of the collection chamber 2201 is a spherical structure, and the height of the center of the sphere at the bottom of the collection chamber 2201 is lower than the height of the center of the cross-section circles at both ends of the central cavity 2102; the diameter of the central cavity 2102 gradually decreases from the center to both sides; after the adipocyte matrix produced by centrifugation enters the collection chamber 2201, it will accumulate at the bottom of the collection chamber 2201, and the height of the bottom of the collection chamber 2201 is lower than the height of the two ends of the central cavity 2102, which can effectively prevent the target product from flowing back into the central cavity 2102 after centrifugation.

[0099] As shown in Figure 13, the bottom of the collection chamber 2201 has a sphere, and the center line of the sampling channel 2202 points to the sphere of the collection chamber 2201. When the sampler 240 is inserted into the collection chamber 2201 through the sampling channel 2202, it can point to the bottom of the collection chamber 2201 to ensure thorough sampling. At the same time, the top of the sampling channel 2202 is provided with an interface 2204 for connecting to an external negative pressure source to sample or recover the target product in the collection chamber 2201.

[0100] The buffer solution container 3 is a buffer solution container bag suspended at a high place; it is suspended on the suspension rod of the setting platform 10; the waste liquid collection container 4 is a waste liquid collection bag suspended on the setting platform 10, and its overall structure hangs below the setting platform 10; this arrangement can effectively reduce the working intensity of the power pump 7.

[0101] The buffer solution is sodium lactate Ringer's solution.

[0102] A procedure for removing fat from the human body during surgery and then enriching and cleaning the fat matrix components;

[0103] S1: Using liposuction instruments to extract fat from the human body for subsequent processes such as fat cleaning, fat breakdown, fat matrix component enrichment, and fat matrix component cleaning.

[0104] S2: Install the tubing. Position the fat processing structure 1, centrifugal enrichment structure 2, waste liquid collection container 4, and buffer solution container in appropriate locations. Prepare the tubing installation. Match the color-coded guide structures 403 on the main guide line 401 and branch guide lines 402 with the color-coded matching structures on the main pipeline 5 and branch pipelines to complete the tubing placement. Then, connect the main pipeline 5 to the power pump. Connect each branch pipeline to its corresponding clamp valve 6 and the pressure detection tube to the pressure detection valve. Finally, connect each branch pipeline to the fat processing structure 1, centrifugal enrichment structure 2, waste liquid collection container 4, and buffer solution container.

[0105] S3: Pipeline inspection, check for leaks at the connections of each pipeline. If no leaks are found, proceed to the next step.

[0106] S4: The fat is fed into the fat processing structure 1 and allowed to stand for separation. After separation, the waste liquid is transported to the waste liquid collection container 4 through the second transmission channel. The fat is then weighed until a sufficient amount of fat is reached before proceeding to the next step.

[0107] S5: Cleaning of adipose tissue. The buffer solution is transferred from the buffer solution container 3 to the adipose tissue treatment structure 1 through the first transfer path to clean the adipose tissue. After cleaning, the waste liquid is transported to the waste liquid collection container 4 through the second transfer path.

[0108] S6: Lysis of adipose tissue. The lysis solvent is added to the adipose treatment structure. Then, the buffer solution is transferred to the adipose treatment structure via the transfer pathway to lyse the cleaned adipose tissue. After lysis, the treatment vessel is allowed to stand for five minutes for separation. The adipose matrix components are separated. Note: The lysis solvent added in this step is Celase or an equivalent reagent.

[0109] S7: Enrichment of fatty matrix components. The separated fatty matrix components are transferred from the fatty treatment structure 1 through the three-transfer pathway to the centrifuge chamber of the centrifugal enrichment device for enrichment by centrifugation. After enrichment, the enriched waste liquid is transferred from the centrifugal enrichment structure 2 to the waste liquid collection container 4 through the four-transfer pathway.

[0110] S8: Cleaning of the fatty matrix components. After the fatty matrix components are enriched, they are cleaned three times in the centrifuge chamber. Before cleaning, the buffer solution is transferred from the buffer solution container 3 to the centrifuge chamber of the centrifuge enrichment structure 2 using the transfer pathway 5. After each cleaning, the waste liquid is transferred from the centrifuge enrichment structure 2 to the waste liquid collection container 4 using the transfer pathway 4 and then collected.

[0111] S9: Clinical preparation of adipose tissue. The aspirated fat is re-extracted and injected into the cleaned adipose tissue processing structure 1 for separation. After separation, the waste liquid is discharged, followed by further cleaning and drainage. Then, the adipose matrix components are injected into the adipose tissue processing structure 1, and the fat and adipose matrix components are mixed by agitation.

[0112] The fat extraction and cleaning processes involved in step S9 and the fat matrix component cleaning processes in step S8 are carried out simultaneously in the fat processing structure and the centrifugation enrichment device, respectively. This setup can greatly reduce the processing time of the fat and fat matrix components introduced into the human body.

[0113] The technical solutions of the embodiments of the present invention have been clearly and completely described above through specific embodiments. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Those skilled in the art can easily understand other advantages and effects of the present invention from the content disclosed in this specification. The present invention can also be implemented or applied through other different specific embodiments. In the absence of conflict, the above embodiments and features in the embodiments can be combined with each other. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

Claims

1. A system for enriching and cleaning fatty matrix components, comprising: A fat processing structure, which connects an output pipe and an input pipe; A centrifugal enrichment structure is connected to an output pipeline and an input pipeline. A buffer solution container connected to an output tubing; A waste liquid collection container, which is connected to an inlet pipe; A main pipeline is connected to input pipelines one to three and output pipelines one to three respectively; input pipeline three and output pipeline three are connected to the two edges of the main pipeline in the vertical direction; input pipeline one, output pipeline one, input pipeline two and output pipeline two are located between input pipeline three and output pipeline three; input pipeline one and output pipeline one are located on one side of the main pipeline in the vertical direction, and input pipeline two and output pipeline two are located on the other side of the main pipeline in the vertical direction. A power pump is installed on the main pipeline, with three pipelines on each side of the power pump; A pinch valve is installed on each of the input lines 1 to 3 and the output lines 1 to 3.

2. The enrichment and cleaning system according to claim 1, characterized in that, It includes 5 transmission paths, namely: The first transmission pathway from the buffer container to the fat processing structure is composed of the third output line, the main line, and the first input line. The second transmission path from the fat processing structure to the waste liquid collection container is composed of the first output pipeline, the main pipeline and the third input pipeline. The third transmission pathway, from the fat processing structure to the centrifugal enrichment structure, is composed of output pipeline one, main pipeline and input pipeline two. The fourth transmission path from the centrifugal enrichment structure to the waste liquid collection container is composed of the second output pipeline, the main pipeline and the third input pipeline. The fifth transport pathway from the buffer container to the centrifugal enrichment structure consists of the third output line, the main line, and the second input line.

3. The enrichment and cleaning system according to claim 2, characterized in that, Input pipe 1 and input pipe 2 are connected to the main pipeline at the same vertical axis position; output pipe 1 and output pipe 2 are connected to the main pipeline at the same vertical axis position; input pipe 1 and input pipe 2 are closer to input pipe 3; while output pipe 1 and output pipe 2 are set closer to output pipe 3.

4. The enrichment and cleaning system according to claim 3, characterized in that, Two pressure detection tubes and / or one liquid addition / extraction tube are connected and installed at the edge of the main pipeline in the vertical direction; a pressure detection valve is installed on the outside of the pressure detection tube; and a liquid addition / extraction head is installed on the liquid addition or extraction tube.

5. The enrichment and cleaning system according to claim 4, characterized in that, The main pipeline is configured with three sections: output pipelines one through three and input pipelines one through three, forming a complete main pipeline. The three sections of the main pipeline are designated as the first section, the second section, and the third section. The first section has a two-way pipe (connected to output pipeline three) at its first end; a four-way pipe (connected to input pipeline one through the first section, second section, and input pipeline two through the four-way pipe); the second section has a four-way pipe (connected to output pipeline one through the second section, third section, and output pipeline two through the four-way pipe); and the third section has a two-way pipe (connected to output pipeline three) at its second end. The power pump is located outside the second section.

6. The enrichment and cleaning system according to claim 4, characterized in that, All pinch valves and power pumps are mounted on a platform; the platform is equipped with guide signs to facilitate pipeline installation. The guide signs are located between the pinch valves and include a main guide line and six branch guide lines corresponding to the pipeline.

7. The enrichment and cleaning system according to claim 6, characterized in that, At least one color-guided structure is set on the main guide line; at least one color-guided structure is set on the branch guide line, and a corresponding color matching structure is set on the main pipeline corresponding to the main guide line and the branch pipeline corresponding to the branch guide line; the color-guided structure is a color-marking block or a color-marking sticker set on the main guide line and the branch guide line, and the color matching structure is a color-marking ring set on the main pipeline and the branch pipeline, with the color-marking ring sleeved on the outside of the pipeline.

8. The enrichment and cleaning system according to claim 7, characterized in that, Two color-coded guide structures are set on the main guide line, and two color-coded guide structures are set on the branch guide lines. The two color-coded guide structures on the main guide line are set on the first and third sections of the pipeline. The two color-coded guide structures on the branch guide lines are set on the branch guide lines corresponding to the output pipeline and the input pipeline connected to the centrifugal enrichment structure. The two color-coded guide structures on the main and branch guide lines are different colors. Alternatively, two color-coded guide structures can be set on the main guide line and two color-coded guide structures can be set on the branch guide lines. The two color-coded guide structures on the main guide line are set on the first and third sections of the pipeline. The two color-coded guide structures on the branch guide lines are set on the branch guide lines corresponding to the output pipeline and input pipeline connected to the fat processing structure. The two color-coded guide structures on the main and branch guide lines are different colors.

9. The enrichment and cleaning system according to claim 2, characterized in that, The centrifugal enrichment structure is installed inside a covered centrifuge chamber. Output line 2 and input line 2 extend into the lower part of the cover of the centrifuge chamber and the central axis of the centrifugal enrichment structure. The centrifugal enrichment apparatus includes a transverse enrichment structure, with the central axis located in the middle of the transverse enrichment structure. The rotation of the centrifugal enrichment structure will not cause the central axis to rotate.

10. The enrichment and cleaning system according to claim 9, characterized in that, The central pipeline is rotatably connected to the transverse enrichment structure, and sealing material is installed at the connection to maintain a leak-proof seal. Alternatively, a temperature maintenance structure can be installed on the hatch. The temperature maintenance structure is a temperature maintenance ring that extends from the center of the hatch and surrounds the central axis pipe. The temperature maintenance ring has a longitudinal notch for connecting the second output pipe and the second input pipe. The wires of the temperature maintenance structure are guided to the power supply position through the hatch. Alternatively, a heating plate can be installed at the bottom of the centrifuge chamber to maintain the temperature of the entire centrifuge chamber.

11. The enrichment and cleaning system according to claim 9, characterized in that, The lateral enrichment structure includes: a lateral enrichment structure body and a collection chamber; The main body of the transverse enrichment structure has an outer shell and a central cavity inside the outer shell; the collection chamber is connected to both ends of the outer shell, and the collection cavity inside the collection chamber is connected to the central cavity; the collection chamber is integrally formed with the main body of the transverse enrichment structure, and the collection chamber and the central cavity are always in communication. The upper end of the collection chamber is provided with a sampling channel that penetrates the collection chamber, and the sampling channel is provided with a sealing structure; the sealing structure has two states: open and closed. When the sealing structure is in the open state, the collecting chamber is in communication with the outside. When the sealing structure is in the closed state, the collection chamber is cut off from the outside world.

12. The enrichment and cleaning system according to claim 11, characterized in that, The sealing structure is an elastic seal A, which is inserted into the sampling channel; the seal A and the sampling channel are interference-fitted.

13. The enrichment and cleaning system according to claim 12, characterized in that, A sampler is inserted inside the seal A, and the sampler penetrates the seal A and is inserted into the bottom of the collection chamber; the sampler is a slender tubular structure.

14. The enrichment and cleaning system according to claim 11, characterized in that, The sealing structure is a spherical seal B; the sampling channel has an installation groove in the middle, and one end of the installation groove coincides with the sampling channel; the installation groove is provided with a seal B whose outer surface is in close contact with the inner wall of the installation groove, and the seal B rolls along the installation groove; the diameter of the seal B is larger than the diameter of the sampling channel.

15. The enrichment and cleaning system according to claim 14, characterized in that, A magnetic column is fixedly connected to the other end of the mounting groove; the sealing element B is ferromagnetic.

16. The enrichment and cleaning system according to claim 11, characterized in that, The bottom of the collecting cavity is a spherical structure, and the height of the center of the sphere at the bottom of the collecting cavity is lower than the height of the center of the cross-section circles at both ends of the central cavity; the diameter of the central cavity gradually decreases from the center to both sides.

17. The enrichment and cleaning system according to claim 16, characterized in that, The bottom of the collection chamber has a sphere center, and the center line of the sampling channel points to the sphere center of the collection chamber.

18. The enrichment and cleaning system according to claim 6, characterized in that, The setup platform also includes: The mounting plate has a valve connecting section and a pump connecting section on its working surface. The valve connecting section has a mating port for the clamping part of the clamping valve to enter, and the pump connecting section has a working port for the roller of the power pump head to enter, and an extrusion plate located in the working port and capable of forming an extrusion channel with the roller. Both the valve connecting section and the pump connecting section have pipeline channels for the main pipeline to pass through. The mating port and the working port are connected to the pipeline channels, and the openings of the mating port and the working port face the same direction. The host unit and the mounting plate are detachably connected; The opening of the mating port and the working port is oriented in a first direction, which is parallel to the working surface. The working surface is provided with multiple valve connecting parts. The host is provided with an instrument space, which includes a first space and a second space. The second space is provided with a power pump head and multiple clamp valves. The first space and the second space are arranged sequentially along the first direction. The clamping part of the clamp valve is provided with a pipe installation port. The orientation of the pipe installation port is opposite to the first direction. When the mounting plate is connected to the host, the connecting pump section and the connecting valve section that enter the first space move along the first direction and eventually enter the second space, so that the multiple pipeline installation ports enter each mating port respectively. At the same time, the roller of the power pump head enters the working port and can squeeze the main pipeline passing through the squeezing channel.

19. The enrichment and cleaning system according to claim 18, characterized in that, The instrument space is provided with three first spaces and three second spaces. The three second spaces are arranged sequentially along a first direction. A first space is provided between two adjacent second spaces. The remaining first space is located on one side of the three second spaces at the starting position of the first direction. The power pump head is provided in the second space located between the two second spaces, and multiple clamp valves are provided in the other second spaces respectively; The mounting plate is provided with two sets of connecting valve sections and a connecting pump section located between the two sets of connecting valve sections, and the connecting valve sections and the connecting pump section are spaced apart in a first direction.

20. The enrichment and cleaning system according to claim 18, characterized in that, The rotating end face of the power pump head is parallel to the working surface.

21. The enrichment and cleaning system according to claim 20, characterized in that, The projection of the working port onto the working surface is arc-shaped. The rotation path of the roller around the pump head rotation axis passes through the working port and partially coincides with the extension direction of the working port. The roller can extend into the working port and squeeze the main pipeline in the squeezing channel.

22. The enrichment and cleaning system according to claim 18, characterized in that, The pipeline control and heating structure is also provided with a heating tank and a heating unit connected to the heating tank, the heating unit being able to heat the working liquid in the heating tank; The heating tank and the heating unit are located on the host unit, the first space and the second space are located on the heating tank, or the heating tank is located on the mounting plate, the heating unit is located on the host unit, the heating tank is connected to the heating unit through a heat conductor, and the pipeline channel passes through the heating tank; When the mounting plate is connected to the host, the main pipeline connected to the mounting plate can be immersed in the working liquid heated by the heating unit.

23. The enrichment and cleaning system according to claim 18, characterized in that, The main unit is equipped with a heating unit, and the mounting plate is equipped with a heat conductor. The heat conductor is connected to the pipeline channel. When the main unit is connected to the mounting plate, the heating unit is connected to the heat conductor and can heat the main pipeline in the pipeline channel through the heat conductor.

24. The enrichment and cleaning system according to claim 18, characterized in that, The mounting plate is provided with a guide rail mating part; The host is provided with a first guide rail, the first guide rail extends in the same direction as the first direction, and the first guide rail is provided with a guide rail notch at the installation position, and the guide rail mating part can enter the first guide rail through the guide rail notch; The guide rail mating part that enters the first guide rail through the guide rail notch can move along the first guide rail in the first direction to reach the working position, so that the mating port is connected to the pipeline connection port, and the roller can extend into the working port.

25. The enrichment and cleaning system according to claim 24, characterized in that, The host is provided with a motion component, which includes a moving part and a second guide rail connected to the host. The second guide rail extends in the same direction as the first direction. The moving part is slidably connected to the second guide rail. The moving part is provided with a locking structure that can be detachably connected to the mounting plate. When the moving component moves along the first direction on the second guide rail, the moving component drives the mounting plate to move along the first guide rail in the first direction, so that the mounting plate reaches the working position; When the moving component moves along the second guide rail in a direction opposite to the first direction, the moving component drives the mounting plate to move along the first guide rail in a direction opposite to the first direction, so that the pipeline connection port leaves the mating port, the roller leaves the working port, and finally reaches the installation position.

26. The enrichment and cleaning system according to claim 25, characterized in that, The main unit is equipped with a heating unit and a heating tank connected to the heating unit. The working surface is perpendicular to the depth direction of the heating tank. The instrument space is located inside the heating tank. When the mounting plate is connected to the main unit and reaches the working position, the mounting plate closes the communication between the heating tank and the outside world.

27. A method for enriching and cleaning fatty acid matrix components using the enrichment and cleaning system according to any one of claims 1-26, characterized in that, S1: The extracted fat is sent into the fat processing structure, left to stand and separate. After separation, the waste liquid is transported to the waste liquid collection container through the second transmission channel, and the fat is weighed until a sufficient amount of fat is reached. S2: Cleaning of adipose tissue. The buffer solution is transferred from the buffer solution container to the adipose tissue treatment structure through the first transfer channel to clean the adipose tissue. After cleaning, the waste liquid is transported to the waste liquid collection container through the second transfer channel. S3: Lysis of adipose tissue. The lysis solvent is added to the adipose treatment structure. Then, the buffer solution is transferred to the adipose treatment structure through the transfer channel from the buffer container to lyse the cleaned adipose tissue. After the post-treatment tank is left to stand for five minutes, the adipose matrix components are separated. S4: Enrichment of fatty matrix components. The separated fatty matrix components are transferred to a centrifugal enrichment device through transport pathway three for enrichment. After enrichment, the waste liquid is transferred to a waste liquid collection container through transport pathway four. S5: Cleaning of fatty matrix components. After the fatty matrix components are enriched, they are cleaned in the centrifuge chamber. The buffer solution is transferred to the centrifugation enrichment structure for cleaning using the transfer pathway five. After cleaning, the waste liquid is discharged through the transfer pathway four times.

28. A method for preparing a fatty matrix component, characterized in that, The fatty matrix component obtained directly using the method described in claim 27.

29. The method for preparing the fatty matrix component according to claim 28, characterized in that, The fat matrix component obtained by the method of claim 27 is mixed with the cleaned fat; The preparation steps for cleaned fat are as follows: fat aspirate is injected into the cleaned fat processing structure for separation, waste liquid is discharged after separation and then cleaned again, and the waste liquid is discharged after cleaning.

30. The method for preparing the fatty matrix component according to claim 29, characterized in that, The washing of the aspirated fat within the fat processing structure and the washing of the fat matrix components within the centrifugation enrichment structure are carried out simultaneously.

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