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Open-loop intelligent insulin pump control method

An insulin pump and control method technology, applied in medical preparations containing active ingredients, pharmaceutical formulations, metabolic diseases, etc., can solve the problems of large fluctuations in blood sugar levels, difficult to complete, difficult to achieve ideal levels, etc., and achieve precise and accurate treatment. Safe and effective in reducing hyper/hypoglycemia

Active Publication Date: 2012-11-07
珠海福尼亚医疗设备有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, the calculation of residual active insulin is a very professional and complicated work, let alone patients, even full-time medical staff are often difficult to complete
Because it is too difficult, clinically, doctors either ignore it or roughly estimate it according to an empirical value (such as linear decay at a rate of 15-30% per hour), and it is even more difficult for patients to inject themselves, resulting in large fluctuations in blood sugar levels. Difficult to achieve ideal level

Method used

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  • Open-loop intelligent insulin pump control method
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  • Open-loop intelligent insulin pump control method

Examples

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Comparison scheme
Effect test

example 1

[0052] Example 1: A diabetic patient has a carbohydrate index of 8 g / unit, an insulin sensitivity coefficient of 20 mg / dL / unit, a target blood sugar of 140 mg / dL, and a blood sugar of 220 mg 4 hours after infusion of 12 units of rapid-acting insulin / dL, at this point, he wants to snack on around 40 grams of carbohydrates. Ask him how many units of insulin he should take?

[0053] Such as Figure 5 As shown, enter the corresponding parameters on the left side of the preprandial insulin dosage calculation interface, and click the "Calculate" button, and the patient's preprandial insulin dosage at this time is 5.635 units in the output results on the right.

example 2

[0054] Example 2: If the above patient wants to eat a snack of about 40 grams of carbohydrates after 3 hours, and assume that the measured blood sugar is still 220 mg / dL at this time. How many units of insulin should he inject?

[0055] Such as Image 6 As shown, modify the parameter of "Injection Time Interval" on the left side of the pre-meal insulin dosage calculation interface to 3, and keep the rest unchanged. At this time, after clicking the "Calculate" button, the output result on the right shows that the patient's preprandial insulin dosage at this time is 5 units.

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Abstract

The present invention relates to a method of controlling the amount of insulin before meal. The present invention confirms whether the action of residual active insulin is taken into account by judging whether conventional or rapid-acting insulin is injected within a certain period of time. When taking the action of residual active insulin into account, the method of interpolation and numerical integration is adopted to accurately measure the residual amount of in vivo active insulin according to insulin pharmacodynamical data, thus more accurately measuring the insulin amount required before meal. The present invention can effectively reduce hyperglycemia / hypoglycemia caused by improper insulin amount, thus making the treatment more accurate and safer. In addition, the concept and method of measuring insulin amount provided by the present invention is also applicable to the measurement of insulin amount not before meal, which deserves promotion and application.

Description

technical field [0001] The invention relates to a control method of an open-loop intelligent insulin pump. Background technique [0002] Diabetes is a chronic disease that endangers the health of the social population. Its degree of harm ranks third among all diseases and continues to increase. Practice has proved that insulin is the most effective drug for controlling blood sugar and preventing various serious complications. Since the human body's demand for insulin is expressed in two forms: a continuous basal amount and a relatively large dose (supplementary amount) after a meal, insulin injection therapy is also designed for this characteristic. The traditional injection method is manual injection, that is, clinicians or patients manually inject long-acting or ultra-long-acting insulin once a day to meet the basic needs of the human body for insulin. In addition, short-acting or fast-acting insulin is administered before each meal Injection is to meet the needs of post...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/28A61P3/10
Inventor 瞿雪芬
Owner 珠海福尼亚医疗设备有限公司
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