Positioning assembly and bioreactor
By designing a multi-angle adjustable positioning component, the problem of poor installation flexibility of traditional electrode hooks is solved, achieving stable installation of the test piece and adaptability to various states, avoiding electrode damage and culture bag tilting, and improving the operability and reliability of the equipment.
Patent Information
- Application Number
- CN202211705851.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2022-12-29
- Publication Date
- 2026-08-25
- Estimated Expiration
- 2042-12-29
AI Technical Summary
Traditional electrode hooks are unidirectional and fixed, resulting in poor installation flexibility of electrode detection components. They cannot meet the installation requirements of multiple angles or multiple states, and are prone to causing culture bags to tilt or electrodes to be damaged.
A positioning assembly was designed, comprising a fixed base, a fixing component, an adjusting component, and a hook component. Through the cooperation of the adjusting component and the hook component, the detection piece can be installed at multiple angles and positions. The threaded connection of the slide, the slide rail, and the positioning component ensures the stability and flexibility of the installation.
It enables precise and secure installation of the test pieces, meets installation requirements at various angles and under various conditions, avoids electrode damage and culture bag misalignment, and improves the operability and reliability of the equipment.
Smart Images

Figure CN116103121B_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of biopharmaceutical technology, and in particular to positioning components and bioreactors. Background Technology
[0002] With the rapid development of the biopharmaceutical field, the requirements for equipment in biopharmaceutical manufacturing are also increasing. Equipment is developing towards diversification and multi-functionality. Operators are also placing greater emphasis on the operability of the equipment.
[0003] Electrodes (such as pH electrodes and DO electrodes) are often used in equipment to monitor the culture medium and adjust it in a timely manner to ensure its growth and operation. However, because traditional electrodes are relatively rigid and require precise assembly, electrode hooks are often used to support the electrodes and maintain their stable assembly.
[0004] However, current electrode hooks are all unidirectional and fixed, which limits the installation of pH electrodes and other detection devices to some extent. This makes them unsuitable for installation at multiple angles or in various configurations, resulting in poor flexibility. Furthermore, since electrodes and other detection devices are mostly made of metal or glass, they should be fixed after assembly. If there is a misalignment between the electrode hook and the electrode position, the electrode must be forcibly fixed to the hook during installation. This may cause the culture bag opening to become misaligned, subject the electrode to additional stress, and even damage the glass electrode, resulting in additional economic losses. Summary of the Invention
[0005] Therefore, it is necessary to provide a positioning component to meet the various installation requirements of the detection component.
[0006] A positioning component includes a fixed base, a fixing component, an adjusting component, and a hook component. The fixing component is mounted on the fixed base, the adjusting component is connected to the fixing component, the hook component is rotatably adjustable relative to the adjusting component at an adjustable angle, and the hook component is slidable along the adjusting component to adjust its mounting position on the adjusting component.
[0007] With this configuration, the detection component can be fixed on the hook assembly, which in turn can rotate the detection component on the adjustment assembly to adjust the installation angle of the detection component. In addition, the hook assembly can also drive the detection component to slide along the adjustment assembly to adjust the installation position of the detection component on the adjustment assembly. Thus, this positioning assembly can meet the installation requirements of the detection component at various angles and in various states while ensuring accurate and reliable installation.
[0008] In one embodiment, the adjusting component includes an adjusting member, on which a first groove and a slide rail are provided that communicate with each other, the first groove and the slide rail extending in the same direction; the hook assembly can extend into the first groove, the hook assembly includes a hook member, one end of the hook member is radially provided with a slider, the slider matches the slide rail and can slide along the slide rail.
[0009] With this configuration, the hook assembly can be attached to the adjusting component via the slider on the hook, making it less likely to fall off. At the same time, the rod of the hook and the protruding slider can slide within the first slide groove and slide track, allowing the hook to move on the adjusting component and adjust the position of the hook assembly on the adjusting component.
[0010] In one embodiment, the hook assembly further includes a first positioning member, one end of which has a first positioning hole. The first positioning member can be threadedly connected to the first positioning hole and fix the hook member at any position on the slide rail.
[0011] With this configuration, the threaded connection between the first positioning component and the first positioning hole makes processing and operation easier. Once the hook component moves to the desired position on the adjusting component, simply tightening the first positioning component will allow it to abut against the adjusting component, restricting the movement of the slider and the hook component, thus fixing the hook component in the desired position and meeting the installation requirements of the test component.
[0012] In one embodiment, the slide rail passes through the adjusting member and forms a hollow structure; and / or, the outer peripheral wall of the slider does not protrude from the outer peripheral wall of the adjusting member.
[0013] This design makes the hollowed-out slide easy to process and shape, reducing costs; the fact that the outer wall of the slider does not protrude from the outer wall of the adjusting part can prevent the slider from being accidentally touched or activated after installation, thus causing the position of the hook to change.
[0014] In one embodiment, the slide is U-shaped; and / or, the bottom of the adjusting member has a mounting groove at one end relative to the fixing component, the mounting groove is connected to the first slide groove and the slide, and the size of the mounting groove is larger than the size of the first slide groove and the slide, the mounting groove is used to install the slider into the slide.
[0015] With this design, the slider protruding on the hook can be inserted into the slide rail through the mounting groove at the bottom. The mounting groove is located at the bottom of the adjusting component, which reduces the limitation on the size of the hook and increases the selectivity of the hook size. The U-shaped slide rail allows the hook to move more flexibly.
[0016] In one embodiment, the adjusting member is a rounded cuboid; and / or, the hook member includes a hook for hooking the detection member, the hook being arc-shaped and having a hemispherical end.
[0017] With this design, the outer walls of both the adjusting and hook components have no sharp structures, which can prevent damage to the testing components and culture bags during the assembly of the positioning components or accidental injury to the staff during operation.
[0018] In one embodiment, the installation angle of the adjusting component relative to the fixed component is rotatable and adjustable.
[0019] This configuration allows the adjustment components and hook components to work together to further adjust the installation angle of the test piece from multiple directions and angles, meeting the usage needs of various scenarios.
[0020] In one embodiment, the adjusting member has an adjusting hole and a second positioning hole that communicate with each other at one end relative to the fixing component, and the adjusting component further includes a second positioning component; the fixing component can extend into the adjusting hole and rotate relative to the adjusting hole to adjust the installation angle, and the second positioning component can be threaded to the second positioning hole to fix the fixing component and the positioning component together.
[0021] With this configuration, the adjusting component can rotate relative to the fixed component to adjust its installation angle. When the adjusting component rotates to the required installation angle, tightening the second positioning piece will fix the adjusting component, keeping its installation angle constant. This, in turn, keeps the installation position and state of the test piece stable, ensuring the test results.
[0022] In one embodiment, there are multiple second positioning holes, which are spaced apart around the adjustment hole.
[0023] This design allows users to easily find the appropriate angle to fix the second positioning component, adapting to different installation environments, thanks to the multiple positioning holes at different positions and angles.
[0024] In one embodiment, the fixed base is provided with a second slide groove, the fixed component includes a third positioning member and a sliding member, one end of the sliding member is connected to the adjusting component, the sliding member can slide along the second slide groove and drive the adjusting component to move, and the third positioning member can fix the sliding member at any position in the second slide groove.
[0025] With this configuration, the testing component can move in multiple directions through the cooperation of the hook assembly, adjustment assembly, and fixing assembly, further improving the flexibility of the testing component's installation position.
[0026] In one embodiment, the fixing component further includes a stop member that protrudes radially from the end of the slider that is relatively away from the fixing base, the slider extending into the adjustment hole, and the stop member preventing the slider from sliding out of the adjustment hole.
[0027] This design enhances the connection stability between the fixed component and the adjusting component, preventing the adjusting component from detaching from the fixed component during adjustment.
[0028] In one embodiment, the fixing seat is arc-shaped, and the curvature of the fixing seat is adapted to the curvature of the cylindrical part in the culture tank.
[0029] This design allows the curved mounting base to match the shape of the cylindrical part of the culture tank, facilitating the installation and fixation of the mounting base.
[0030] In one embodiment, the second slide is an arc-shaped groove, and the arc of the second slide is the same as the arc of the fixed seat.
[0031] With this configuration, the fixing component can maintain a constant angle with the central axis of the cylindrical part of the culture tank when it moves within the second slide groove of the fixing seat, thus achieving the effect of changing only the installation position of the detection element without changing the installation angle of the detection element when the fixing component is moved.
[0032] In one embodiment, the slider has an anti-rotation surface on each of its opposite sides. The anti-rotation surface is an arc surface, and the arc of the anti-rotation surface is the same as the arc of the second groove.
[0033] This design prevents the slider from rotating within the second groove, ensuring that the slider can only slide along the second groove.
[0034] The present invention also provides a bioreactor, including a culture tank and a positioning component installed in the culture tank, the positioning component being used to position a test piece; the positioning component includes the positioning component described above.
[0035] With this configuration, the bioreactor provided by the present invention can install and adjust the installation angle and position of the detection element through the positioning component, so that the detection element can adapt to various installation environments and usage requirements, avoiding damage to the detection element or unsatisfactory detection results.
[0036] In one embodiment, the culture tank includes a cylindrical portion and a frustum portion, the cylindrical portion being connected to the large-diameter end of the frustum portion and located at the top of the frustum portion; the fixing seat is mounted on the outer wall of the culture tank.
[0037] This setup makes it easier to fix and adjust the installation angle and position of the testing component using the positioning components.
[0038] In one embodiment, an annular protrusion is provided on the outer peripheral wall of the cylindrical portion relative to the end of the frustum portion, and an installation step is provided on the fixing seat. The fixing seat is fitted to the cylindrical portion and the annular protrusion through the installation step.
[0039] This design allows the mounting base to fit snugly against the outer wall of the culture tank, resulting in higher installation strength and stability of the mounting base and preventing it from wobbling and affecting the overall stability of the positioning assembly. Attached Figure Description
[0040] Figure 1 This is a schematic diagram of the positioning component provided in an embodiment of the present invention from a first perspective;
[0041] Figure 2 for Figure 1 A schematic diagram of the positioning component from a second-view perspective;
[0042] Figure 3 for Figure 1 A schematic diagram of the positioning component from a third-person perspective;
[0043] Figure 4 for Figure 1 A schematic diagram of the positioning component from a fourth-person perspective;
[0044] Figure 5 for Figure 1 A schematic diagram of the adjustment mechanism of the positioning component from a first-view perspective;
[0045] Figure 6 for Figure 1 A schematic diagram of the adjustment mechanism of the positioning component from a second perspective;
[0046] Figure 7 for Figure 1 A schematic diagram of the hook assembly of the positioning component;
[0047] Figure 8 for Figure 7 Exploded view of the hook assembly;
[0048] Figure 9 for Figure 1 A partial structural diagram of the fixed component in the middle;
[0049] Figure 10 for Figure 1 Schematic diagram of the structure of the fixed component;
[0050] Figure 11 for Figure 10 Exploded view of the fixed component in the middle;
[0051] Figure 12 This is a schematic diagram of the structure of a bioreactor provided in one embodiment of the present invention;
[0052] Figure 13 for Figure 12 A magnified view of point X in the middle.
[0053] Figure label:
[0054] 100. Positioning component; 10. Fixing base; 101. Horizontal plate; 102. Vertical plate; 11. Second slide groove; 12. Mounting step; 13. Fixing hole; 20. Fixing component; 21. Third positioning component; 211. Tightening part; 212. Limiting part; 2121. Mounting hole; 22. Sliding component; 221. First connecting part; 222. Sliding part; 2221. Anti-rotation surface; 223. Second connecting part; 23. Stop; 30. Adjustment component ; 31. Adjusting component; 311. First slide groove; 312. Slide track; 313. Mounting groove; 314. Adjusting hole; 315. Second positioning hole; 32. Second positioning component; 40. Hook assembly; 41. Hook component; 411. Hook part; 412. Slider; 413. First positioning hole; 42. First positioning component; 200. Bioreactor; 210. Culture tank; 2101. Cylindrical part; 21011. Annular convex ring; 2102. Frustum. Detailed Implementation
[0055] To make the above-mentioned objects, features, and advantages of the present invention more apparent and understandable, specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a thorough understanding of the present invention. However, the present invention can be practiced in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.
[0056] In the description of this invention, it should be understood that the terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," and "circumferential" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention.
[0057] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this invention, "a plurality of" means at least two, such as two, three, etc., unless otherwise explicitly specified.
[0058] In this invention, unless otherwise explicitly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise explicitly limited. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.
[0059] In this invention, unless otherwise expressly specified and limited, the first feature is "on" or "below" the second feature.
[0060] The first and second features can be in direct contact, or they can be in indirect contact through an intermediate medium. Furthermore, "above," "over," or "on top of" the first feature relative to the second feature can mean the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. The first feature is above the second feature.
[0061] The features “below,” “under,” and “below” can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal height than the second feature.
[0062] It should be noted that when a component is described as "fixed to" or "set on" another component, it can be directly on the other component or there may be an intervening component. When a component is considered to be "connected" to another component, it can be directly connected to the other component or there may be an intervening component. This article uses...
[0063] The terms “vertical,” “horizontal,” “up,” “down,” “left,” “right,” and similar expressions used are for illustrative purposes only and do not represent the only possible implementation.
[0064] With the rapid development of the biopharmaceutical field, the requirements for equipment in biopharmaceutical manufacturing are also increasing. Equipment is evolving towards diversification and multi-functionality. Operators are also placing greater emphasis on the operability of the equipment. Electrodes (such as pH electrodes and DO electrodes) are frequently used in these devices to monitor the culture media within the equipment.
[0065] Monitoring is required, and the culture medium should be adjusted promptly to ensure proper growth. Because traditional electrodes are relatively rigid and require precise assembly, electrode hooks are often needed to support the electrodes and maintain their stable assembly.
[0066] However, current electrode hooks are all unidirectional and fixed, which limits the installation of pH electrodes and other detection components to some extent, failing to meet the needs of multi-angle or multi-state installation and resulting in poor flexibility. Furthermore, since electrodes and other detection components are mostly made of metal or glass, they should be fixed after assembly. If the electrode hook and electrode...
[0067] If the position is off, the electrode needs to be forcibly fixed to the electrode hook during installation, which may cause the opening of the culture bag to be skewed, the electrode to be subjected to additional stress, or even damage the glass electrode, resulting in additional economic losses.
[0068] Based on this, see Figure 1 , Figure 1 This is a schematic diagram of the positioning component 100 provided in an embodiment of the present invention from a first perspective. It is necessary to provide a positioning component 100, which is commonly used in the field of biological cell culture technology and can also be used in other fields that require positioning detection devices, including but not limited to the fields of chemistry, fermentation and other technical fields.
[0069] Please see again Figure 1 See also Figures 2 to 4 , Figure 2 for Figure 1 A schematic diagram of the positioning component 100 from a second perspective; Figure 3 for Figure 1 A schematic diagram of the positioning component 100 from a third-person perspective; Figure 4 for Figure 1 A schematic diagram of the positioning component 100 from a fourth-person perspective; the positioning component 100 includes a fixed base 10, a fixing component 20, an adjusting component 30, and a hook component 40. The fixing component 20 is mounted on the fixed base 10, the adjusting component 30 is connected to the fixing component 20, the mounting angle of the hook component 40 relative to the adjusting component 30 can be rotated and adjusted, and the hook component 40 can slide along the adjusting component 30 to adjust its mounting position on the adjusting component 30.
[0070] With this configuration, the detection component of the present invention can be fixed on the hook assembly 40, and the hook assembly 40 can drive the detection component to rotate on the adjustment assembly 30, thereby adjusting the installation angle of the detection component; in addition, the hook assembly 40 can also drive the detection component to slide along the adjustment assembly 30, thereby adjusting the installation position of the detection component on the adjustment assembly 30. In this way, the positioning assembly 100 can meet the installation requirements of the detection component at multiple angles and in multiple states while ensuring accurate and reliable installation of the detection component.
[0071] It is understood that the detection device is an external component, including but not limited to pH electrode, dissolved oxygen electrode, etc.
[0072] In this embodiment, the adjusting component 30 includes an adjusting member 31, on which a first sliding groove 311 and a sliding track 312 are provided that communicate with each other. The first sliding groove 311 and the sliding track 312 extend in the same direction. The hook component 40 can extend into the first sliding groove 311. The hook component 40 includes a hook member 41, one end of which has a radially protruding slider 412. The slider 412 matches the sliding track 312 and can slide along the sliding track 312. With this configuration, the hook component 40 can be hung on the adjusting component 31 via the slider 412 on the hook member 41, making it less likely to fall off. At the same time, the rod of the hook member 41 and the protruding slider 412 can slide within the first sliding groove 311 and the sliding track 312, allowing the hook member 41 to move on the adjusting component 31 and adjust the position of the hook component 40 on the adjusting component 31.
[0073] Furthermore, in this embodiment, the hook 41 and the slider 412 are integrally formed, which facilitates processing and assembly; it can be understood that in other embodiments, the hook 41 and the slider 412 can also be formed separately and then fixedly connected, as long as it does not affect the cooperation and function of the two.
[0074] It is further important to note that "adjustable installation angle" means the angle can be adjusted before installation, and the position remains fixed after installation; "rotatable adjustment" means the angle can still be rotated after installation. For an example, please refer again... Figures 1 to 3 Taking the detection element as an electrode as an example, in this embodiment, after the electrode is installed on the hook assembly 40, a fixed installation angle is maintained between it and the hook assembly 40. However, the hook assembly 40 can still drive the electrode to move. Figure 3 The electrode rotates relative to the adjusting member 31 in the direction of A, and can drive the electrode along the adjusting member 31. Figure 3 Slide in direction B.
[0075] Furthermore, in this embodiment, the hook assembly 40 also includes a first positioning member 42. One end of the hook member 41 has a first positioning hole 413. The first positioning member 42 can be threadedly connected to the first positioning hole 413, fixing the hook member 41 at any position on the slide rail 312. With this configuration, the threaded connection between the first positioning member 42 and the first positioning hole 413 facilitates processing and operation. After the hook member 41 moves to the desired position on the adjusting member 31, simply tightening the first positioning member 42 will cause it to abut against the adjusting member 31, restricting the movement of the slider 412 and the hook member 41, fixing the hook member 41 in the desired position, and meeting the installation requirements of the detection component.
[0076] It is understood that in other embodiments, the first positioning member 42 and the first positioning hole 413 can also be connected in other ways, including but not limited to elastic fastening, flexible fastening, etc., as long as the first positioning member 42 and the first positioning hole 413 are detachably connected.
[0077] Please see again Figures 1 to 3 It should be noted that after the first positioning component 42 is tightened, it can... Figure 3 The rotation of the hook 41 is restricted in direction A, and the movement of the detection element is also restricted along the direction A. Figure 3 The B direction slides on the adjusting member 31.
[0078] Furthermore, in this embodiment, the slide 312 penetrates the adjusting member 31 and forms a hollow structure. The hollow structure of the slide 312 is easy to process and form, reducing costs, and also reducing the overall weight of the adjusting member 31. It can be understood that in other embodiments, the slide 312 may also be an inner groove formed in the adjusting member 31, that is, a U-shaped groove or an annular groove is formed on the inner wall of the adjusting member 31. In other words, the shape of the slide 312 only needs to allow the hook member 41 to move along the adjusting member 31.
[0079] Furthermore, the outer peripheral wall of the slider 412 does not protrude beyond the outer peripheral wall of the adjusting member 31. This design prevents the slider 412 from being accidentally touched or activated after installation, which could lead to a change in the position of the hook member 41.
[0080] Furthermore, the thickness of the slider 412 is matched with the height of the slide 312, which can prevent the hook 41 from moving up and down in the slide 312 and ensure that the slider 412 does not fall off or wobble when sliding back and forth in the slide 312.
[0081] Furthermore, in this embodiment, the slide 312 is U-shaped, which allows for more flexible movement of the hook 41. It is understood that in other embodiments, the slide 312 may also be annular, as long as it does not affect the sliding of the hook 41 along the extending direction of the first groove 311.
[0082] Furthermore, the bottom of the adjusting member 31, near the fixed component 20, has a mounting groove 313. The mounting groove 313 connects to the first sliding groove 311 and the slide rail 312, and its size is larger than that of the first sliding groove 311 and the slide rail 312. The mounting groove 313 is used to install the slider 412 into the slide rail 312. With this configuration, the slider 412 protruding from the hook member 41 can be inserted into the slide rail 312 through the mounting groove 313 at the bottom. The mounting groove 313's location at the bottom of the adjusting member 31 reduces restrictions on the size of the hook member 41, increasing the flexibility in hook size selection. It is understood that when the first positioning member 42 is loosened, the slider 412 can disengage downwards from the mounting groove 313. Preferably, the center of the end of the first sliding groove 311 near the mounting groove 313 is on a vertical line with the centerline of the mounting groove 313.
[0083] Please see again Figure 1 See also Figures 5 to 8 , Figure 5 for Figure 1 A schematic diagram of the adjustment element 31 of the positioning component 100 from a first-view perspective; Figure 6 for Figure 1 A schematic diagram of the adjustment element 31 of the positioning component 100 from a second perspective; Figure 7 for Figure 1 A schematic diagram of the hook assembly 40 of the positioning component 100; Figure 8 for Figure 7 An exploded view of the hook assembly 40; in this embodiment, the adjusting member 31 is a rounded cuboid; the hook member 41 includes a hook portion 411 for hooking the detection piece, the hook portion 411 is arc-shaped, and the end of the hook portion 411 is hemispherical. With this configuration, the outer peripheral walls of both the adjusting member 31 and the hook member 41 have no sharp structures, which can prevent damage to the electrodes during the assembly of the positioning assembly 100 or accidental injury to personnel during operation.
[0084] Furthermore, the installation angle of the adjusting component 30 relative to the fixed component 20 can be adjusted by rotation. With this configuration, the adjusting component 30 and the hook component 40 work together to further adjust the installation angle of the detection component from multiple directions and angles, meeting the usage requirements in various scenarios.
[0085] For example, please see again Figures 1 to 3 The adjusting member 31 of the adjusting component 30 can drive the hook assembly 40 and the detection element on the hook assembly 40 along... Figure 3 The C-direction rotates relative to the fixed component 20.
[0086] Furthermore, in this embodiment, the adjusting member 31 has an adjusting hole 314 and a second positioning hole 315 that are interconnected at the end relatively close to the fixing component 20. The adjusting component 30 also includes a second positioning member 32. The fixing component 20 can extend into the adjusting hole 314 and rotate relative to the adjusting hole 314 to adjust the installation angle. The second positioning member 32 can be threaded into the second positioning hole 315 to fix the fixing component 20 to the positioning member. With this configuration, the adjusting component 30 can rotate relative to the fixing component 20 to adjust the installation angle of the adjusting component 30. When the adjusting component 30 rotates to the required installation angle, tightening the second positioning member 32 can achieve the effect of fixing the adjusting component 30, keeping the installation angle of the adjusting component 30 unchanged, thereby keeping the installation position and state of the detection component stable and ensuring the detection effect. In other words, after the adjusting member 31 rotates to a certain angle along the C direction, tightening the second positioning member 32 can fix the adjusting member 31 at that installation angle, preventing the adjusting member 31 from driving the hook component 41 and the detection component on the hook component 41 to rotate relative to the fixing component 20.
[0087] Furthermore, there are multiple second positioning holes 315, which are spaced apart around the adjustment hole 314. This arrangement allows the user to easily find a suitable angle to fix the second positioning component 32 at different positions and angles, adapting to different installation environments.
[0088] Please see again Figure 1 and Figure 2 In this embodiment, each of the two opposing side walls of the adjusting member 31 is provided with a second positioning hole 315.
[0089] Furthermore, depending on the requirements, as long as they can play a corresponding fixing role, the first positioning element 42 and the second positioning element 32 may be implemented as stepped knurled screws, including but not limited to.
[0090] Please see again Figures 1 to 4 Furthermore, in this embodiment, the fixing base 10 has a second sliding groove 11, and the fixing component 20 includes a third positioning member 21 and a sliding member 22. One end of the sliding member 22 is connected to the adjusting component 30. The sliding member 22 can slide along the second sliding groove 11 and drive the adjusting component 30 to move. The third positioning member 21 can fix the sliding member 22 at any position in the second sliding groove 11. With this configuration, the detection member can move in multiple directions through the cooperation between the hook component 40, the adjusting component 30, and the fixing component 20, further improving the flexibility of the installation position of the detection member. In other words, the sliding member 22 of the fixing component 20 can drive the adjusting component 31, the hook member 41 on the adjusting component 31, and the detection member on the hook member 41 to move in different directions. Figure 3The slider 22 rotates relative to the fixed base 10 in the D direction. After the slider 22 slides to a certain position in the second slide groove 11 along the D direction, the slider 22 can be fixed in that position by the third positioning member 21, so that the slider 22 cannot drive the adjustment component 30, the hook component 40 and the detection component to move relative to the fixed base 10.
[0091] Furthermore, the third positioning member 21 and the sliding member 22 are connected by a thread. Tightening the third positioning member 21 can fix the position of the sliding member 22 on the second slide groove 11.
[0092] For further details, please refer to [link / reference]. Figure 1 See also Figures 9 to 11 , Figure 9 for Figure 1 A partial structural diagram of the fixing component 20; Figure 10 for Figure 1 A schematic diagram of the structure of the fixing component 20; Figure 11 for Figure 10 An exploded view of the fixed component 20; the third positioning component 21 includes a screwing part 211 and a limiting part 212 connected to each other. The radial dimension of the limiting part 212 is greater than the width of the second slide groove 11. The limiting part 212 has a mounting hole 2121 on the side away from the screwing part 211. The sliding component 22 includes a first connecting part 221, a sliding part 222 and a second connecting part 223 connected in sequence. The sliding part 222 is located in the second slide groove 11 and can slide along the second slide groove 11. The radial dimension of the first connecting part 221 is smaller than the width of the second slide groove 11. The end of the first connecting part 221 away from the second connecting part 223 can pass through the second slide groove 11 and connect with the mounting hole 2121 of the limiting part 212. The radial dimension of the second connecting part 223 is greater than the width of the second slide groove 11 so that the sliding component 22 is not easily dislodged from the second slide groove 11.
[0093] Furthermore, the end of the first connecting part 221 that is relatively far away from the second connecting part 223 is threadedly connected to the mounting hole 2121 of the limiting part 212, and the end of the second connecting part 223 that is relatively far away from the first connecting part 221 is rotatably connected to the adjusting assembly 30.
[0094] Furthermore, the first connecting part 221, the sliding part 222 and the second connecting part 223 can be integrally formed or separately formed and then fixedly connected.
[0095] It should be noted that both the screwing part 211 and the limiting part 212 are cylindrical, and the radial dimension of the screwing part 211 is larger than that of the limiting part 212, which facilitates the user to screw on the third positioning member 21. When screwing, when the bottom wall of the limiting part 212 abuts against the fixed seat 10, it means that the position of the sliding member 22 in the second slide groove 11 is fixed by the third positioning member 21.
[0096] Furthermore, in this embodiment, the fixing component 20 also includes a stop 23, which protrudes radially from the end of the sliding member 22 that is relatively far from the fixing base 10. The sliding member 22 extends into the adjustment hole 314, and the stop 23 can prevent the sliding member 22 from sliding out of the adjustment hole 314. This arrangement can enhance the connection stability between the fixing component 20 and the adjustment component 30, and prevent the adjustment member 31 from detaching from the fixing component 20 during the adjustment process. Specifically, in this embodiment, the stop 23 protrudes from the end of the second connecting portion 223 that is relatively far from the first connecting portion 221.
[0097] It is understood that in other embodiments, the stop 23 may not be provided, and the sliding member may be fixed by the second positioning member 32 to prevent the sliding member 22 from disengaging from the adjustment hole 314.
[0098] Furthermore, in this embodiment, the slider 22 has an anti-rotation surface 2221 on each of its opposite sides. The anti-rotation surface 2221 is an arc surface, and the arc of the anti-rotation surface 2221 is the same as the arc of the second slide groove 11. This arrangement can prevent the slider 22 from rotating within the second slide groove 11, ensuring that the slider 22 can only slide along the second slide groove 11. Specifically, in this embodiment, the anti-rotation surface 2221 is provided on the sliding portion 222 of the slider 22.
[0099] Please see again Figure 2 and Figure 3 Furthermore, the mounting base 10 is arc-shaped, and the curvature of the mounting base 10 matches the curvature of the cylindrical portion 2101 in the culture tank 210. With this configuration, the arc-shaped mounting base 10 can match the shape of the cylindrical portion 2101 of the culture tank 210, which facilitates the installation and fixation of the mounting base 10.
[0100] Please see again Figure 4 Furthermore, the second slide groove 11 is an arc-shaped groove, and the arc of the second slide groove 11 is the same as the arc of the fixed base 10. With this configuration, when the fixed component 20 moves within the second slide groove 11 of the fixed base 10, it can always maintain a constant angle with the central axis of the cylindrical part 2101 of the culture tank 210, achieving the effect that moving the fixed component 20 only changes the installation position of the detection element, without changing the installation angle of the detection element.
[0101] Please see again Figure 2 Furthermore, the fixing base 10 includes a vertical plate 102 and a horizontal plate 101 connected to each other. The second slide groove 11 is formed on the horizontal plate 101. The vertical plate 102 and the horizontal plate 101 both have an arc that matches the cylindrical part 2101 of the culture tank 210. In other words, the arc of the inner and outer diameters of the second slide groove 11, the vertical plate 102 and the horizontal plate 101 are the same as the center of the cylindrical part 2101 of the culture tank 210.
[0102] Furthermore, the vertical plate 102 is provided with fixing holes 13, and the fixing seat 10 can be connected to the culture tank 210 through the vertical plate 102. The connection method includes, but is not limited to, spot welding the vertical plate 102 to the culture tank 210 through the fixing holes 13, or connecting the vertical plate 102 to the culture tank 210 through the fixing holes 13 and screws.
[0103] It is understood that the number of second slide grooves 11 opened on the fixed base 10, the number of fixing components 20, the number of adjusting components 30, and the number of hook components 40 can all be selected according to requirements. In this embodiment, there are three of each of the four, and they are arranged in three groups in a one-to-one correspondence. In other words, the positioning component 100 can cope with the use of up to three electrodes, and each hook component 40 is independent of each other and can independently cope with the special needs of different electrode installations.
[0104] Optionally, all structural parts of the positioning component 100 are made of 304 stainless steel.
[0105] Please see Figure 12 and Figure 13 , Figure 12 This is a schematic diagram of the structure of a bioreactor 200 provided in one embodiment of the present invention; Figure 13 for Figure 12 Enlarged schematic diagram at point X. This invention also provides a bioreactor 200, including a culture tank 210 and a positioning component 100 installed in the culture tank 210. The positioning component 100 is used to position the test specimen; the positioning component 100 includes the aforementioned positioning component 100. With this configuration, the bioreactor 200 provided by this invention can install and adjust the installation angle and position of the test specimen through the positioning component 100, enabling the test specimen to adapt to various installation environments and usage requirements, avoiding damage to the test specimen or unsatisfactory detection results.
[0106] Furthermore, the culture vessel 210 includes a cylindrical portion 2101 and a frustum portion 2102. The cylindrical portion 2101 is connected to the large-diameter end of the frustum portion 2102 and is located at the top of the frustum portion 2102; the fixing seat 10 is installed on the outer wall of the culture vessel 210. This arrangement allows for easier fixing and adjustment of the installation angle and position of the test specimen using the positioning component 100.
[0107] Please see again Figure 13Furthermore, an annular protrusion 21011 is provided on the outer peripheral wall of the cylindrical portion 2101 relative to the end of the frustum portion 2102, and an installation step 12 is provided on the fixing seat 10. The fixing seat 10 is fitted to the cylindrical portion 2101 and the annular protrusion 21011 through the installation step 12. This arrangement allows the fixing seat 10 to fit snugly against the outer wall of the culture tank 210, making the installation strength of the fixing seat 10 higher and more stable, and preventing the fixing seat 10 from shaking and affecting the overall stability of the positioning assembly 100. In other words, the installation step 12 makes the thickness of the upper part of the vertical plate 102 greater than the thickness of the lower part. Thus, the annular protrusion 21011 of the cylindrical portion 2101 can cooperate with the installation step 12 on the fixing seat 10 to provide a certain degree of support and bearing for the fixing seat 10, thereby enhancing the installation stability of the fixing seat 10.
[0108] Furthermore, the fixing hole 13 is formed in the lower part of the vertical plate 102 where the thickness is smaller. Preferably, the mounting step 12 makes the angle formed between the upper and lower parts of the vertical plate 102 an obtuse angle.
[0109] Furthermore, the bioreactor 200 also includes a bioreactor bag. The interface between the bioreactor bag and the electrode is located below the horizontal plate 101 of the fixing base 10. One end of the electrode is connected to the interface of the bioreactor bag, and the other end is placed on the hook 41. The positioning component 100 can drive the electrode to move and adjust in multiple directions and angles to adapt to various installation environments and requirements, and can ensure adjustment accuracy. It can effectively adapt to the positional deviation that occurs when installing detection components such as metal or stripped electrodes, so that the electrode can be adjusted to a position that does not bear stress on the bioreactor bag and the motor.
[0110] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.
[0111] The embodiments described above are merely illustrative of several implementations of the present invention, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the invention patent. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of the present invention, and these all fall within the protection scope of the present invention. Therefore, the protection scope of this invention patent should be determined by the appended claims.
Claims
1. A positioning component, characterized in that, The device includes a fixed base, a fixed component, an adjusting component, and a hook assembly. The fixed component is mounted on the fixed base, and the adjusting component is connected to the fixed component. The hook assembly can rotate and adjust its installation angle relative to the adjusting component, and it can slide along the adjusting component to adjust its installation position on the adjusting component. The adjusting component includes an adjusting member and a second positioning member. The adjusting member is a rounded cuboid shape and has a first groove and a slide rail that are interconnected. The first groove and the slide rail extend in the same direction. The hook assembly can extend into the first groove and includes a hook member. One end of the hook member has a radially protruding slider. The slider matches the slide rail and can slide along the slide rail. The thickness of the slider is adapted to the height of the slide rail. The hook assembly also includes a first positioning member. One end of the hook member has a first positioning hole. The first positioning member can be threaded into the first positioning hole and fix the hook member at any position on the slide rail. The slide rail passes through the adjusting member and forms a hollow structure. The fixed base has a second sliding groove. The fixing assembly includes a third positioning member and a sliding member. One end of the sliding member is connected to the adjusting member. The installation angle of the adjusting member relative to the sliding member can be rotated and adjusted. The sliding member can slide along the second sliding groove and drive the adjusting member to move. The third positioning member can fix the sliding member at any position in the second sliding groove. The fixed base includes a vertical plate and a horizontal plate connected to each other. The second sliding groove is opened on the horizontal plate. Both the vertical plate and the horizontal plate have an arc that matches the outer wall of the culture tank. The adjusting member has an adjusting hole and a second positioning hole that are connected to each other at one end relative to the sliding member; The sliding member can extend into the adjustment hole and rotate relative to the adjustment hole to adjust the installation angle. The second positioning member can be threaded into the second positioning hole and fix the sliding member and the adjustment member in place.
2. The positioning component according to claim 1, characterized in that, The outer peripheral wall of the slider does not protrude beyond the outer peripheral wall of the adjusting member.
3. The positioning component according to claim 1, characterized in that, The slide is U-shaped; and / or, The bottom of the adjusting component has a mounting groove at one end relative to the fixed component. The mounting groove is connected to the first slide groove and the slide rail, and the size of the mounting groove is larger than the size of the first slide groove and the slide rail. The mounting groove is used to install the slider into the slide rail.
4. The positioning component according to claim 1, characterized in that, The hook includes a hook for hooking the test piece, the hook being arc-shaped and the end of the hook being hemispherical.
5. The positioning component according to claim 1, characterized in that, There are multiple second positioning holes, which are distributed at intervals around the adjustment hole.
6. The positioning component according to claim 1, characterized in that, The fixing component further includes a stop member, which is radially protruding from the end of the slider that is relatively far from the fixing seat, and the stop member can prevent the slider from sliding out of the adjustment hole.
7. The positioning component according to claim 1, characterized in that, The second groove is an arc-shaped groove, and the arc of the second groove is the same as the arc of the horizontal plate.
8. The positioning component according to claim 7, characterized in that, The sliding member has an anti-rotation surface on each of its opposite sides. The anti-rotation surface is an arc surface, and the arc of the anti-rotation surface is the same as the arc of the second sliding groove.
9. A bioreactor, characterized in that, The device includes a culture vessel and a positioning component installed on the culture vessel, the positioning component being used to position the test piece; the positioning component includes the positioning component according to any one of claims 1 to 8.
10. The bioreactor according to claim 9, characterized in that, The culture tank includes a cylindrical part and a frustum part, the cylindrical part is connected to the large-diameter end of the frustum part and is located at the top of the frustum part; the fixing seat is installed on the outer wall of the culture tank.
11. The bioreactor according to claim 10, characterized in that, An annular protrusion is provided on the outer peripheral wall of the cylindrical part relative to the end of the frustum part, and an installation step is provided on the fixing seat. The fixing seat is fitted to the cylindrical part and the annular protrusion through the installation step.
Citation Information
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