Functional nutrition bag for preventing and treating foot pad inflammation of meat ducks as well as preparation method and application of functional nutrition bag

Abstract

The invention relates to the technical field of feed additives, in particular to a functional nutrition bag for preventing and treating foot pad inflammation of meat ducks as well as a preparation method and application thereof, and the functional nutrition bag comprises the following components in parts by weight: 100-200 parts of macleaya cordata extract, 10-30 parts of exogenous enzyme preparation, 3-7 parts of candida krusei, 30-60 parts of zinc, 5-20 parts of astragalus polysaccharide and 100-200 parts of silicon dioxide. According to the invention, a plurality of functional substances are applied to meat ducks which grow quickly according to the pathogenic factors of the foot pad inflammation of the meat ducks. The feed can improve the body health of meat ducks, repair skin barriers, improve the immune function of the whole body and reduce inflammatory quality.

Description

Technical Field

[0001] The invention relates to the technical field of feed additives, and in particular to a functional nutrient package for preventing and treating foot pad inflammation in meat ducks, and a preparation method and application thereof. Background Art

[0002] Foot pad inflammation is a common disease in industrialized meat poultry production. Foot pad inflammation causes hardening and scaling of the soles of the feet, usually with the formation of abnormal keratin. Foot pad inflammation causes the pads to swell and rupture easily, with epidermal exfoliation and tissue necrosis in the middle of the rupture, which leads to heterophilic leukocytes penetrating the germinal layer of the skin. Foot pad inflammation is a contact dermatitis caused by contact between the foot and excrement or the foot pad. Foot pad inflammation not only affects the quality and safety of the product claws, but also affects the welfare of poultry and the economic benefits of breeding. Severe cases can reduce feed intake and production performance. Moreover, the occurrence of foot pad inflammation provides an entry point for pathogens, which proliferate in the foot tissue and have the potential to spread throughout the body.

[0003] Footpad inflammation is the result of the combined effects of water in the litter and chemicals in the litter, such as ammonia. Nutritional factors such as biotin, riboflavin, pantothenic acid, and sulfur-containing amino acid deficiencies can cause footpad inflammation. In addition, intestinal microorganisms in poultry play an important role in regulating immunity and inflammatory diseases. The abundance of beneficial bacteria in the intestines of ducks with footpad inflammation is significantly lower than that of healthy ducks, leading to severe inflammatory reactions.

[0004] At present, most of the research on duck footpad inflammation focuses on single anti-inflammatory additives, and there are few studies on compound nutritional functional packages. Therefore, studying the nutritional functional package for preventing and treating duck footpad inflammation can reduce the incidence of duck footpad inflammation in many aspects, promote feeding, and improve the production performance of ducks. Summary of the invention

[0005] The purpose of the present invention is to provide a functional nutrient package for preventing and treating foot pad inflammation in meat ducks, and a preparation method and application thereof, so as to solve the technical problem of high incidence of foot pad inflammation in the prior art.

[0006] The present invention discloses a functional nutrient package for preventing and treating foot pad inflammation of meat ducks, comprising the following components in parts by weight:

[0007] 100-200 parts of Macleaya cordata extract, 10-30 parts of exogenous enzyme preparation, 3-7 parts of Candida cruzi, 30-60 parts of zinc, 5-20 parts of astragalus polysaccharide and 100-200 parts of silicon dioxide.

[0008] Furthermore, the invention comprises the following components by weight: 110-200 parts of Macleaya cordata extract, 20-30 parts of exogenous enzyme preparation, 4-7 parts of Candida krusei, 41-60 parts of zinc, 9-20 parts of astragalus polysaccharide and 120-200 parts of silicon dioxide.

[0009] Furthermore, the invention comprises the following components by weight: 110-150 parts of Macleaya cordata extract, 20-25 parts of exogenous enzyme preparation, 4-6 parts of Candida krusei, 41-50 parts of zinc, 9-20 parts of astragalus polysaccharide and 120-158 parts of silicon dioxide.

[0010] Furthermore, the Macleaya cordata extract contains total alkaloids ≥56 g / kg, sanguinarine ≥37 g / kg, and chelerythrine ≥16 g / kg.

[0011] Furthermore, the total number of viable Candida krusei is ≥ 1×10 10 CFU / g.

[0012] Furthermore, the astragalus polysaccharide is selenized astragalus polysaccharide.

[0013] Astragalus polysaccharide is the active ingredient of the traditional Chinese medicine Astragalus. It is easily soluble in water, can regulate the body's immunity, and has antiviral and anti-inflammatory effects. Selenized polysaccharide is an organic compound combined with selenium and polysaccharide, and its biological activity is higher than that of selenium and polysaccharide. Selenium deficiency can cause many diseases in humans and animals.

[0014] Furthermore, the exogenous enzyme preparation is xylanase.

[0015] As an exogenous enzyme preparation, xylanase can hydrolyze the β-1,4-glycosidic bonds of xylan, improve the digestion and absorption of nutrients in the diet by the digestive tract of poultry, reduce the content of undigested nutrients in feces and urine, reduce the content of organic matter in litter, and ultimately reduce the source of infection of foot pad inflammation.

[0016] Furthermore, the zinc is nano zinc oxide.

[0017] A method for preparing a functional nutrient package for preventing and treating foot pad inflammation in meat ducks comprises the following steps: weighing each component according to a weight ratio, adding the components into a mixer in a descending order of the ratio, mixing them evenly and packaging them.

[0018] An application of a functional nutrient package for preventing and treating foot pad inflammation in meat ducks, wherein the nutrient package is suitable for meat ducks after 12 days of age.

[0019] Further, at 10 / m 2 In the breeding environment, add it to the complete feed at a ratio of 0.3%, mix well and then feed.

[0020] Compared with the prior art, the present invention has the following beneficial effects:

[0021] 1. According to the pathogenic factors of duck foot pad inflammation, the present invention applies a variety of functional substances to fast-growing ducks. It improves the health of the ducks themselves, repairs the skin barrier, enhances the immune function of the whole body, and reduces the inflammatory quality;

[0022] 2. The nutrient package of the present invention is used in intensive meat duck farming, which can reduce the incidence and severity of foot pad inflammation in meat ducks, improve animal welfare, improve the sensory quality of duck feet, and meet consumer needs;

[0023] 3. The main components of Macleaya extract are sanguinarine and chelerythrine, which have the effects of inhibiting inflammation, anti-inflammatory, improving immunity and promoting growth, improving the intestinal morphology and microbial colony structure of poultry, etc. Macleaya extract can regulate the body level, improve the body's immunity, and improve the intestinal morphology of meat ducks and regulate the intestinal microbial structure;

[0024] 4. Intestinal health and microbial communities are not only crucial for digestion and absorption, but also play an important role in the health of the body. Zinc oxide is beneficial to repair and maintain the barrier function of the skin, which blocks the passage of external pathogens into the body through the skin. At the same time, zinc oxide, like Macleaya cordata extract, has a certain regulatory effect on intestinal health and microbial communities. Zinc oxide also has a certain effect of degrading mycotoxins and sterilizing, which can improve feed quality, skin formation, maintenance, and an essential participant in collagen synthesis. Collagen plays the role of an extracellular structural element in connective tissue. The biological efficacy of nano zinc oxide is higher than that of ordinary zinc oxide. Astragalus polysaccharide is the active ingredient of the traditional Chinese medicine Astragalus, which is easily soluble in water, can regulate the body's immunity, and has antiviral and anti-inflammatory effects;

[0025] 5. The biological activity of selenized polysaccharide is higher than that of selenium and polysaccharide. Since foot pad inflammation can cause secondary arthritis in the legs of meat ducks, selenized polysaccharide can regulate inflammation and prevent bone marrow lesions. It comprehensively improves the body's disease resistance;

[0026] 6. Xylanase, as an exogenous enzyme, helps animals degrade xylan in feed, thereby increasing the release of nutrients in feed;

[0027] 7. Candida albicans can improve the body's nitrogen metabolism and has a strong ability to degrade ammonia nitrogen. Xylanase and Candida albicans can both improve the digestion and absorption of nutrients by animals, increase feed digestibility, reduce the excretion of nutrients in feces and urine, and reduce the content of organic matter in litter, thereby reducing the amount of microorganisms that the duck's foot pads come into contact with, and also improve the air quality of the shed. DETAILED DESCRIPTION

[0028] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention are clearly and completely described below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments.

[0029] Example 1

[0030] The functional nutrient package for preventing and treating foot pad inflammation of meat ducks used in the above device in this embodiment and its preparation method and application include the following components by weight: 125 parts of Macleaya cordata extract, 20 parts of xylanase, 4 parts of Candida krusei (10 10 CFU / g), 41 parts of nano zinc oxide, 10 parts of selenized astragalus polysaccharide, and 100 parts of silicon dioxide. The Macleaya cordata extract contains 56g / kg of total alkaloids, 37g / kg of sanguinarine, and 16g / kg of chelerythrine. Weigh the components by weight, and add them into the mixer in descending order of proportion, mix evenly, and package.

[0031] Example 2

[0032] In this embodiment, as a preferred embodiment of the present invention, a functional nutrient package for preventing and treating foot pad inflammation in meat ducks and its preparation method and application include the following two components: 150 parts of Macleaya cordata extract, 15 parts of xylanase, 6 parts of Candida krusei (10 10 CFU / g), 50 parts of nano zinc oxide, 9 parts of selenized astragalus polysaccharide, and 120 parts of silicon dioxide. The Macleaya cordata extract contains 56g / kg of total alkaloids, 37g / kg of sanguinarine, and 16g / kg of chelerythrine.

[0033] The preparation method is the same as Example 1.

[0034] Example 3

[0035] In this embodiment, as a preferred embodiment of the present invention, a functional nutrient package for preventing and treating foot pad inflammation in meat ducks and a preparation method thereof, comprising the following components by weight: 110 parts of Macleaya cordata extract, 25 parts of xylanase, 7 parts of Candida krusei (10 10 CFU / g), 30 parts of nano zinc oxide, 20 parts of selenized astragalus polysaccharide, and 158 parts of silicon dioxide. The Macleaya cordata extract contains 56g / kg of total alkaloids, 37g / kg of sanguinarine, and 16g / kg of chelerythrine.

[0036] The preparation method is the same as Example 1.

[0037] Experimental Example 1: Feeding Effect of Nutritional Function Pack:

[0038] Under high-density (10 / ㎡) net bed farming conditions, add 0.3% to the complete feed formula for feeding. 480 12-day-old Cherry Valley ducks were selected and randomly divided into 4 groups, with 6 replicates in each group. The control group was fed with commercial feed 522, treatment group 1 was fed with commercial feed 522 + Example 1 nutrient package; treatment 2 was fed with commercial feed 522 + Example 2; treatment 3 was fed with commercial feed + Example 3. The feeding cycle was 30 days. Statistics were taken on growth performance, feed nutrient digestibility, and foot pad scores. Six days before the end of the experiment, one duck with similar weight was randomly selected from each replicate for digestion test. At the end of the experiment, one duck with similar weight was selected from each replicate, and blood was collected from the jugular vein.

[0039] Nutrient apparent utilization rate (%) = 100 × (nutrient content in feed - nutrient content in feces) / nutrient content in feed.

[0040] SPSS 22.0 software was used for one-way ANOVA and Duncan's method for multiple comparisons. The results are expressed as mean ± standard error (SE), P < 0.05 was considered significant, and different superscript letters in the same row indicated significant differences.

[0041] Table 1 Feeding effect of nutritional function package

[0042]

[0043]

[0044] As can be seen from Table 1, compared with the control group, the nutritional function packages of Examples 1-3 significantly improved the growth effect, feed conversion efficiency, feed apparent digestibility, and immune indexes of meat ducks, and improved the degree of foot pad damage of meat ducks. The immune indexes of meat ducks were also improved to varying degrees after adding the patented nutritional package.

[0045] Experimental Example 2: Effects of Nutritional Function Pack Ingredients on Feeding Meat Ducks

[0046] Under high-density (10 / ㎡) net bed farming conditions, add 0.3% to the complete feed formula for feeding.

[0047] 600 Cherry Valley ducks aged 12 days were selected and randomly divided into 5 groups, with 6 replicates in each group. The feeding cycle was 30 days. The control group was fed with commercial feed 522; treatment 1 was fed with commercial feed 522 + Example 1; treatment 2 was fed with commercial feed 522 + Example 1 without Macleaya cordata extract; treatment 3 was fed with commercial feed 522 + Example 1 without xylanase; treatment 4 was fed with commercial feed 522 + Example 1 without Candida cruzi; treatment 5 was fed with commercial feed 522 + Example 1 without nano zinc oxide; treatment 6 was fed with commercial feed + Example 1 without selenized astragalus polysaccharide.

[0048] Table 2 Feeding effect of nutritional function package

[0049]

[0050]

[0051] Through the comparative test in Table 2, it is found that the nutritional enhancer of treatment 2 does not contain Macleaya cordata extract, treatment 3 does not contain xylanase, treatment 4 does not contain Candida krusei, treatment 5 does not contain nano zinc oxide, and treatment 6 does not contain selenized astragalus polysaccharide, which will reduce the ability of each treatment group to improve feed conversion efficiency, regulate immunity, and prevent and alleviate foot pad inflammation. It shows that the effect of preventing and treating foot pad inflammation of meat ducks when the nutrient package of the present invention is added at a dosage of 0.3% without a certain component has an impact, and only when all the components defined in the present invention are present and cooperate with each other can the performance of meat ducks reach the best.

[0052] Comparative Example 3: Effect of Nutritional Function Pack Dosage on Feeding Effect

[0053] 600 12-day-old Cherry Valley ducks were randomly divided into 5 groups, with 6 replicates in each group, and the feeding cycle was 30 days.

[0054] The control group was fed with commercial feed 522; treatment 1 was fed with commercial feed 522+0.1% of embodiment 1; treatment 2 was fed with commercial feed 522+0.2% of embodiment 1; treatment 3 was fed with commercial feed 522+0.3% of embodiment 1; treatment 4 was fed with commercial feed 522+0.4% of embodiment 1.

[0055] Table 3 Feeding effect of different doses of functional package

[0056]

[0057]

[0058] The comparative test in Table 3 shows that adding 0.1-0.4% of the nutritional functional package of the present invention can improve the incidence and morbidity of duck foot pad inflammation, and has an improvement effect on weight gain and feed conversion efficiency. Among them, the 0.3% and 0.4% dosage groups have the best effect, but 0.4% is not cost-effective. Therefore, the effect is most significant when adding 0.3% of the nutritional functional package of the present invention.

[0059] Comparative Example 4: Effect of functional package component replacement on feeding of meat ducks

[0060] Under high-density (10 / ㎡) net bed farming conditions, add 0.3% to the complete feed formula for feeding.

[0061] Cherry Valley ducks aged 12 days were selected and randomly divided into groups with 6 replicates in each group. The feeding cycle was 30 days. The control group was fed with commercial feed 522; treatment 1 was fed with commercial feed 522 + Example 1; treatment 2 was fed with commercial feed 522 + Example 1 (the same amount of moriline replaced the extract of Macleaya cordata, the total alkali content of moriline was 56g / kg, and other components remained unchanged); treatment 3 was fed with commercial feed 522 + Example 1 (the same amount of lactobacillus and Candida albicans were used, and other components remained unchanged); treatment 4 commercial feed 522 + Example 1 (ordinary zinc oxide replaced nano zinc oxide in equal amounts in terms of zinc element, the total zinc content of ordinary zinc oxide was 75%, and other components remained unchanged); treatment 5 commercial feed 522 + Example 1 (a mixture of astragalus polysaccharide and sodium selenite replaced selenized astragalus polysaccharide, sodium selenite and astragalus polysaccharide were prepared into a mixture at a ratio of 2:1, and other components remained unchanged).

[0062] Table 4 Effect of functional package component replacement on feeding of meat ducks

[0063]

[0064]

[0065] Through the comparative test in Table 4, it is found that replacing the components in the nutrition package with products with similar functions can improve the indicators of meat ducks to varying degrees. Among them, the nutrition package of Example 1 has the greatest improvement in the foot pad score. Therefore, the use of the nutrition function package of the present invention has the most significant effect.

[0066] The above are the implementation methods listed in this embodiment, but this embodiment is not limited to the above optional implementation methods. Those skilled in the art can arbitrarily combine the above methods to obtain other various implementation methods. Anyone can derive other various forms of implementation methods under the inspiration of this embodiment. The above specific implementation methods should not be understood as limiting the scope of protection of this embodiment. The scope of protection of this embodiment shall be based on the definition in the claims, and the description can be used to interpret the claims.

Claims

1. A functional nutrient package for preventing and treating foot pad inflammation in meat ducks, characterized in that: The composition comprises the following components in parts by weight: 100-200 parts of Macleaya cordata extract, 10-30 parts of exogenous enzyme preparation, 3-7 parts of Candida cruzi, 30-60 parts of zinc, 5-20 parts of astragalus polysaccharide and 100-200 parts of silicon dioxide.

2. A functional nutrient package for preventing and treating duck foot pad inflammation according to claim 1, characterized in that: The invention comprises the following components by weight: 110-200 parts of Macleaya cordata extract, 20-30 parts of exogenous enzyme preparation, 4-7 parts of Candida cruzi, 41-60 parts of zinc, 9-20 parts of astragalus polysaccharide and 120-200 parts of silicon dioxide.

3. A functional nutrition package for preventing and treating duck foot pad inflammation according to claim 2, characterized in that: The invention comprises the following components by weight: 110-150 parts of Macleaya cordata extract, 20-25 parts of exogenous enzyme preparation, 4-6 parts of Candida cruzi, 41-50 parts of zinc, 9-20 parts of astragalus polysaccharide and 120-158 parts of silicon dioxide.

4. A functional nutrient package for preventing and treating foot pad inflammation in meat ducks according to any one of claims 1 to 3, characterized in that: The total number of viable Candida krusei bacteria is ≥ 1×10 10 CFU / g.

5. A functional nutrient package for preventing and treating foot pad inflammation in meat ducks according to any one of claims 1 to 3, characterized in that: The astragalus polysaccharide is selenized astragalus polysaccharide.

6. A functional nutrient package for preventing and treating foot pad inflammation in meat ducks according to any one of claims 1 to 3, characterized in that: The exogenous enzyme preparation is xylanase.

7. A functional nutrient package for preventing and treating foot pad inflammation in meat ducks according to any one of claims 1 to 3, characterized in that: The zinc is nano zinc oxide.

8. A method for preparing a functional nutrient package for preventing and treating duck foot pad inflammation according to claims 1-7, characterized in that: Weigh each component according to the weight ratio, and add them into the mixer in descending order of proportion, mix well and then package.

9. An application of a functional nutrient package for preventing and treating foot pad inflammation in meat ducks, characterized in that: The nutrient pack prepared according to the functional nutrient pack for preventing and treating foot pad inflammation of meat ducks according to claims 1-7 or the preparation method of the functional nutrient pack for preventing and treating foot pad inflammation of meat ducks according to claim 8 is used for meat ducks after 12 days of age.

10. The use of a functional nutrient package for preventing and treating foot pad inflammation in meat ducks according to claim 9, characterized in that: At 10 / m 2 In the breeding environment, add it to the complete feed at a ratio of 0.3%, mix well and then feed.

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