Water-salt supplement applied to high-temperature environment and application of water-salt supplement
By providing a water-salt supplement containing electrolytes such as sodium chloride, potassium chloride, etc., the problem of electrolyte balance disorder in high-temperature environments is solved, the effect of rapid electrolyte supplementation is achieved, the time for weight-bearing swimming in mice is extended, and the time for weight-bearing is alleviated. The impact of high temperature on the human body.
Patent Information
- Application Number
- CN202411487395.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-23
- Publication Date
- 2025-01-10
AI Technical Summary
In high-temperature environments, the human body loses a lot of water and electrolytes due to sweating, resulting in disorder in the electrolyte balance. The existing technology is difficult to replenish effectively and quickly, resulting in the occurrence of symptoms of water loss and salt loss.
Provide a water-safe supplement containing sodium chloride, potassium chloride, calcium gluconate, magnesium citrate, zinc gluconate, vitamin B1, vitamin B2 and vitamin B6, which can be prepared into solid beverages, liquid beverages or salt pills, etc. Various forms can quickly replenish the substances needed by the human body and can be prepared into sweet, salty and other products according to needs.
This water-salt supplement can effectively supplement the electrolytes in the human body in a high-temperature environment, extend the time for mice to swim with weights, alleviate the impact of high temperature on the experimental subjects, and meet the needs of different groups of people.
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Figure BDA0005099936480000081
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of water-salt supplements, and in particular to a water-salt supplement for use in a high-temperature environment and an application thereof. Background Art
[0002] Electrolytes play an important role in the human body. Water and electrolytes are widely distributed inside and outside cells, participating in many important functions and metabolic activities in the body, and electrolytes play a very important role in maintaining normal life activities. The distribution of electrolytes in the human body is as follows: In a normal human body, sodium ions account for 92% of the total cations in the extracellular fluid, and potassium ions account for about 98% of the total cations in the intracellular fluid. The relative balance of sodium and potassium ions maintains the integrity of the function and structure of the entire cell. Disorders in water and electrolyte metabolism can cause corresponding disorders in the physiological functions of various organ systems throughout the body, especially the cardiovascular system and nervous system, and the body's material metabolism, which can often lead to death in severe cases.
[0003] The balance of water and electrolytes is regulated by the nervous system and certain hormones, and this regulation is mainly achieved through the influence of nerves, especially some hormones, on the kidney's processing of water and electrolytes. (1) Maintaining body fluid osmotic pressure and water balance: Sodium ions and chloride ions are the main inorganic salt ions that maintain the osmotic pressure of intracellular fluid. In normal human bodies, the osmotic pressure of intracellular and extracellular fluids is basically equal, thereby maintaining the dynamic balance of water in intracellular and extracellular fluids. (2) Maintaining the acid-base balance of body fluids: The electrolyte composition of body fluids regulates the acid-base balance. (3) Maintaining the irritability of nerves and muscles: The irritability of nerves and muscles requires a certain concentration and proportion of electrolytes in body fluids to maintain. When sodium ions and potassium ions are too low, the irritability of nerves and muscles decreases, and limb weakness or even paralysis may occur; when calcium ions and magnesium ions are too low, the irritability of nerves and muscles increases, and hand and foot cramps may occur. (4) Maintaining normal cellular metabolism: A variety of inorganic ions act as cofactors of metalloenzymes or metal-activated enzymes to regulate metabolism at the cellular level.
[0004] Maintaining normal water content of various body fluids in a high temperature environment is very important for maintaining a stable internal environment and good endurance. Therefore, the metabolism and supplementation of water and inorganic salts in high temperature nutrition are of considerable significance. The amount of sweating in a high temperature environment varies depending on the humidity, labor intensity and individual quality at the time. The maximum sweating in an hour can reach 1.5 liters, and the maximum sweating in a day can reach more than 10 liters. Since more than 99% of sweat is water, about 0.3% is inorganic salt (mainly sodium chloride). Sodium chloride, mainly sodium ions, is of great significance for maintaining the osmotic pressure and balance of body fluids, maintaining normal muscle contraction and maintaining acid-base balance. When a large amount of water and salt are lost due to sweating, it can cause a disorder of electrolyte balance. If it is not replenished in time, a series of symptoms of water loss and salt loss may occur. Summary of the invention
[0005] The purpose of the present invention is to provide a water-salt supplement for use in a high-temperature environment and its application, so as to quickly supplement substances required by the human body in a high-temperature environment and meet the needs of different groups of people.
[0006] In order to achieve the above-mentioned object of the invention, the present invention provides the following technical solutions:
[0007] The invention provides a water-salt supplement for use in a high-temperature environment. The water-salt supplement comprises the following raw materials in parts by weight: 40-45 parts of sodium chloride, 12.5-16.5 parts of potassium chloride, 13-15 parts of calcium gluconate, 1.3-1.6 parts of magnesium citrate, 0.3-0.4 parts of zinc gluconate, 0.02-0.03 parts of vitamin B1, 0.01-0.02 parts of vitamin B2 and 0.01-0.02 parts of vitamin B6.
[0008] Preferably, the water-salt supplement also includes a sweetener, and the sweetener is a low-intensity sweetener or a high-intensity sweetener.
[0009] Preferably, when the sweetener is a low-intensity sweetener, the added amount of the sweetener is 100 to 300 parts, and the low-intensity sweetener includes glucose, fructose, sucrose, maltose, starch sugar, xylitol, maltitol or erythritol.
[0010] Preferably, when the sweetener is a high-intensity sweetener, the added amount of the sweetener is 0.5 to 1 part, and the high-intensity sweetener includes sucralose, steviol glycoside or mogroside.
[0011] Preferably, the water-salt supplement further includes DHA and EPA, the mass ratio of DHA to EPA is 2-3:5-7, and the added amount of DHA and EPA is 0.5-0.8 parts.
[0012] The present invention also provides the use of the water-salt supplement in preparing a water-salt supplement product for use in a high-temperature environment.
[0013] Preferably, the product comprises a solid beverage, a liquid beverage or a salt pill.
[0014] Preferably, when the product is a solid beverage, the water-salt supplement is diluted with water and then consumed, and the mass ratio of the water-salt supplement to water is 1:20-140.
[0015] Preferably, when the product is a liquid beverage, it is obtained by compounding the water-salt supplement and water, and the mass ratio of the water-salt supplement to water is 1:20-140.
[0016] Preferably, when the product is a salt pill, it can be taken directly, and an appropriate amount of water can be drunk after taking it.
[0017] The present invention provides a water-salt supplement for high temperature environment and its application, comprising the following raw materials in parts by weight: 40-45 parts of sodium chloride, 12.5-16.5 parts of potassium chloride, 13-15 parts of calcium gluconate, 1.3-1.6 parts of magnesium citrate, 0.3-0.4 parts of zinc gluconate, 0.02-0.03 parts of vitamin B1, 0.01-0.02 parts of vitamin B2, and 0.01-0.02 parts of vitamin B6. The water-salt supplement of the present invention has a wide range of raw materials and a reasonable formula. It can be prepared into solid beverages, liquid beverages or salt pills and other products in various forms to quickly supplement the substances needed by the human body in a high temperature environment. At the same time, it can be prepared into various flavors such as sweet and salty, sugar-containing products and "zero sugar" products as needed to meet the needs of different groups of people. DETAILED DESCRIPTION
[0018] The invention provides a water-salt supplement for use in a high-temperature environment. The water-salt supplement comprises the following raw materials in parts by weight: 40-45 parts of sodium chloride, 12.5-16.5 parts of potassium chloride, 13-15 parts of calcium gluconate, 1.3-1.6 parts of magnesium citrate, 0.3-0.4 parts of zinc gluconate, 0.02-0.03 parts of vitamin B1, 0.01-0.02 parts of vitamin B2 and 0.01-0.02 parts of vitamin B6.
[0019] In the present invention, the amount of sodium chloride is preferably 41 to 44 parts, and more preferably 42 to 43 parts.
[0020] In the present invention, the amount of potassium chloride is preferably 13.5 to 15.5 parts, and more preferably 14.5 parts.
[0021] In the present invention, the amount of calcium gluconate is preferably 13.5 to 14.5 parts, more preferably 14 parts.
[0022] In the present invention, the amount of magnesium citrate is preferably 1.4 to 1.5 parts.
[0023] In the present invention, the amount of zinc gluconate is preferably 0.32 to 0.38 parts, more preferably 0.35 parts.
[0024] In the present invention, the amount of vitamin B1 is preferably 0.025 parts.
[0025] In the present invention, the amount of vitamin B2 is preferably 0.015 parts.
[0026] In the present invention, the amount of vitamin B6 is preferably 0.015 parts.
[0027] In the present invention, the water-salt supplement further comprises a sweetener, and the sweetener is a low-intensity sweetener or a high-intensity sweetener.
[0028] In the present invention, when the sweetener is a low-intensity sweetener, the added amount of the sweetener is preferably 100 to 300 parts, more preferably 150 to 200 parts, and the low-intensity sweetener includes glucose, fructose, sucrose, maltose, starch sugar, xylitol, maltitol or erythritol.
[0029] In the present invention, when the sweetener is a high-intensity sweetener, the added amount of the sweetener is preferably 0.5 to 1 part, and more preferably 0.7 to 0.8 part. The high-intensity sweetener includes sucralose, steviol glycoside or mogroside.
[0030] In the present invention, the water-salt supplement preferably also includes DHA and EPA, the mass ratio of DHA and EPA is preferably 2-3:5-7, more preferably 2.5:6, and the added amount of DHA and EPA is preferably 0.5-0.8 parts, more preferably 0.6-0.7.
[0031] The present invention also provides the use of the water-salt supplement in preparing a water-salt supplement product for use in a high-temperature environment.
[0032] In the present invention, the product includes a solid beverage, a liquid beverage or a salt pill.
[0033] In the present invention, when the product is a solid beverage, the water-salt supplement is diluted with water and then drunk. The mass ratio of the water-salt supplement to water is preferably 1:20-140, more preferably 1:50-110, and even more preferably 1:80.
[0034] In the present invention, when the product is a liquid beverage, it is obtained by compounding the water-salt supplement and water. The mass ratio of the water-salt supplement and water is preferably 1:20-140, more preferably 1:50-110, and even more preferably 1:80.
[0035] In the present invention, when the product is a salt pill, it can be taken directly, and an appropriate amount of water can be drunk after taking it.
[0036] In the present invention, when the product is salt pills, it also contains 10 to 20 parts of a binder, and the binder is preferably pregelatinized starch.
[0037] The technical solutions provided by the present invention are described in detail below in conjunction with the embodiments, but they should not be construed as limiting the protection scope of the present invention.
[0038] Example 1
[0039] A method for preparing a liquid beverage for water and salt supplementation in a high temperature environment comprises the following steps:
[0040] (1) Weigh raw materials according to the mass ratio of 40 parts of sodium chloride, 16.5 parts of potassium chloride, 13 parts of calcium gluconate, 1.6 parts of magnesium citrate, 0.4 parts of zinc gluconate, 0.03 parts of vitamin B1, 0.02 parts of vitamin B2, and 0.01 parts of vitamin B6, and set aside;
[0041] (2) mixing sodium chloride, potassium chloride, calcium gluconate, magnesium citrate, zinc gluconate and water to obtain a mixed solution 1;
[0042] (3) sterilizing the mixed solution 1 to obtain a mixed solution 2;
[0043] (4) Mix the mixed solution 2, vitamin B1, vitamin B2 and vitamin B6 to obtain the liquid beverage.
[0044] Note: The amount of water used is 40 times the total mass of sodium chloride, potassium chloride, calcium gluconate, magnesium citrate, zinc gluconate, vitamin B1, vitamin B2 and vitamin B6.
[0045] Example 2
[0046] A method for preparing a liquid beverage for water and salt supplementation in a high temperature environment comprises the following steps:
[0047] (1) Weigh raw materials according to the mass ratio of 150 parts of glucose, 45 parts of sodium chloride, 12.5 parts of potassium chloride, 15 parts of calcium gluconate, 1.3 parts of magnesium citrate, 0.3 parts of zinc gluconate, 0.02 parts of vitamin B1, 0.01 parts of vitamin B2, and 0.02 parts of vitamin B6, and set aside;
[0048] (2) mixing glucose, sodium chloride, potassium chloride, calcium gluconate, magnesium citrate, zinc gluconate and water to obtain a mixed solution 1;
[0049] (3) sterilizing the mixed solution 1 to obtain a mixed solution 2;
[0050] (4) Mix the mixed solution 2, vitamin B1, vitamin B2 and vitamin B6 to obtain the liquid beverage.
[0051] Note: The amount of water used is 80 times the total mass of glucose, sodium chloride, potassium chloride, calcium gluconate, magnesium citrate, zinc gluconate, vitamin B1, vitamin B2 and vitamin B6.
[0052] Example 3
[0053] A method for preparing a liquid beverage for water and salt supplementation in a high temperature environment comprises the following steps:
[0054] (1) Weigh the raw materials according to the mass ratio of 1 part of stevioside, 43 parts of sodium chloride, 14.5 parts of potassium chloride, 14 parts of calcium gluconate, 1.5 parts of magnesium citrate, 0.35 parts of zinc gluconate, 0.025 parts of vitamin B1, 0.015 parts of vitamin B2, and 0.015 parts of vitamin B6, and set aside;
[0055] (2) mixing stevioside, sodium chloride, potassium chloride, calcium gluconate, magnesium citrate, zinc gluconate and water to obtain a mixed solution 1;
[0056] (3) sterilizing the mixed solution 1 to obtain a mixed solution 2;
[0057] (4) Mix the mixed solution 2, vitamin B1, vitamin B2 and vitamin B6 to obtain the liquid beverage.
[0058] Note: The amount of water used is 140 times the total mass of stevioside, sodium chloride, potassium chloride, calcium gluconate, magnesium citrate, zinc gluconate, vitamin B1, vitamin B2 and vitamin B6.
[0059] Example 4
[0060] A method for preparing a solid beverage for water-salt supplementation in a high-temperature environment comprises the following steps:
[0061] (1) Weigh the raw materials according to the mass ratio of 300 parts of erythritol, 45 parts of sodium chloride, 16.5 parts of potassium chloride, 15 parts of calcium gluconate, 1.3 parts of magnesium citrate, 0.3 parts of zinc gluconate, 0.02 parts of vitamin B1, 0.02 parts of vitamin B2, and 0.01 parts of vitamin B6, and set aside;
[0062] (2) mixing erythritol, sodium chloride, potassium chloride, calcium gluconate, magnesium citrate and zinc gluconate to obtain a mixture 1;
[0063] (3) sterilizing the mixed material 1 to obtain the mixed material 2;
[0064] (4) Mixing the mixed material 2, vitamin B1, vitamin B2 and vitamin B6 to obtain the solid beverage.
[0065] Example 5
[0066] A method for preparing a solid beverage for water-salt supplementation in a high-temperature environment comprises the following steps:
[0067] (1) Weigh the raw materials according to the mass ratio of 0.5 parts of sucralose, 40 parts of sodium chloride, 12.5 parts of potassium chloride, 13 parts of calcium gluconate, 1.6 parts of magnesium citrate, 0.4 parts of zinc gluconate, 0.03 parts of vitamin B1, 0.01 parts of vitamin B2, and 0.02 parts of vitamin B6, and set aside;
[0068] (2) mixing sucralose, sodium chloride, potassium chloride, calcium gluconate, magnesium citrate and zinc gluconate to obtain a mixture 1;
[0069] (3) sterilizing the mixed material 1 to obtain the mixed material 2;
[0070] (4) Mixing the mixed material 2, vitamin B1, vitamin B2 and vitamin B6 to obtain the solid beverage.
[0071] Example 6
[0072] A method for preparing a solid beverage for water-salt supplementation in a high-temperature environment comprises the following steps:
[0073] (1) Weigh raw materials according to the mass ratio of 42 parts of sodium chloride, 15 parts of potassium chloride, 14 parts of calcium gluconate, 1.4 parts of magnesium citrate, 0.4 parts of zinc gluconate, 0.02 parts of vitamin B1, 0.015 parts of vitamin B2, and 0.015 parts of vitamin B6, and set aside;
[0074] (2) mixing sodium chloride, potassium chloride, calcium gluconate, magnesium citrate and zinc gluconate to obtain a mixture 1;
[0075] (3) sterilizing the mixed material 1 to obtain the mixed material 2;
[0076] (4) Mixing the mixed material 2, vitamin B1, vitamin B2 and vitamin B6 to obtain the solid beverage.
[0077] Example 7
[0078] A method for preparing salt pills for water-salt supplementation in a high-temperature environment comprises the following steps:
[0079] (1) Weigh raw materials according to the mass ratio of 10 parts of pregelatinized starch, 45 parts of sodium chloride, 12.5 parts of potassium chloride, 15 parts of calcium gluconate, 1.6 parts of magnesium citrate, 0.3 parts of zinc gluconate, 0.02 parts of vitamin B1, 0.01 parts of vitamin B2, and 0.01 parts of vitamin B6, and set aside;
[0080] (2) mixing pregelatinized starch, sodium chloride, potassium chloride, calcium gluconate, magnesium citrate and zinc gluconate to obtain a mixture 1;
[0081] (3) sterilizing the mixed material 1 to obtain the mixed material 2;
[0082] (4) Mix the mixed material 2, vitamin B1, vitamin B2 and vitamin B6 and compress the mixture into tablets to obtain the salt pills.
[0083] Example 8
[0084] A method for preparing salt pills for water-salt supplementation in a high-temperature environment comprises the following steps:
[0085] (1) Weigh raw materials according to the mass ratio of 0.7 parts of sucralose, 12 parts of pregelatinized starch, 40 parts of sodium chloride, 16.5 parts of potassium chloride, 13 parts of calcium gluconate, 1.3 parts of magnesium citrate, 0.4 parts of zinc gluconate, 0.03 parts of vitamin B1, 0.02 parts of vitamin B2, and 0.02 parts of vitamin B6, and set aside;
[0086] (2) mixing sucralose, pregelatinized starch, sodium chloride, potassium chloride, calcium gluconate, magnesium citrate and zinc gluconate to obtain a mixture 1;
[0087] (3) sterilizing the mixed material 1 to obtain the mixed material 2;
[0088] (4) Mix the mixed material 2, vitamin B1, vitamin B2 and vitamin B6 and compress the mixture into tablets to obtain the salt pills.
[0089] Example 9
[0090] A method for preparing salt pills for water-salt supplementation in a high-temperature environment comprises the following steps:
[0091] (1) Weigh the raw materials according to the mass ratio of 0.6 parts of DHA and EPA mixture, 0.9 parts of mogroside, 11 parts of pregelatinized starch, 43 parts of sodium chloride, 14.5 parts of potassium chloride, 14 parts of calcium gluconate, 1.5 parts of magnesium citrate, 0.35 parts of zinc gluconate, 0.025 parts of vitamin B1, 0.015 parts of vitamin B2, and 0.015 parts of vitamin B6, and set aside;
[0092] (2) mixing a mixture of DHA and EPA, mogroside, pregelatinized starch, sodium chloride, potassium chloride, calcium gluconate, magnesium citrate and zinc gluconate to obtain a mixture 1;
[0093] (3) sterilizing the mixed material 1 to obtain the mixed material 2;
[0094] (4) Mix the mixed material 2, vitamin B1, vitamin B2 and vitamin B6 and compress the mixture into tablets to obtain the salt pills.
[0095] Note: The mass ratio of DHA to EPA in the DHA and EPA mixture is 3:7.
[0096] Test Example 1 Water maze test
[0097] Fifty mice (weight 21 g ± 2 g) were randomly divided into 10 groups, 5 mice in each group, numbered as control group and experimental groups 1-9.
[0098] Before the experiment, mice in each group were subjected to 7 days of adaptive feeding under the same conditions, during which they were allowed to eat and drink freely. After the adaptive feeding, mice in each group were placed in an environment of 42.5±0.5℃ and 60±10% relative humidity for 60 minutes to obtain mice with water and salt deficiency.
[0099] Then, the products prepared in Examples 1 to 9 were respectively administered to the mice in the test groups 1 to 9 at a standard of 0.17 g / kg (Note: 0.17 g is calculated only on the basis of sodium chloride, potassium chloride, calcium gluconate, magnesium citrate, zinc gluconate, vitamin B1, vitamin B2 and vitamin B6 in the sample, excluding sweeteners, binders, DHA and EPA). The mice in the control group were not given any products prepared in Examples 1 to 9. The mice in each group were then allowed to rest for 60 minutes and drink water freely.
[0100] After the rest, mice in each group were subjected to Morris water maze test. The statistical test results showed that the latency of mice in the control group to step onto the stage was significantly longer than that of mice in test groups 1 to 9.
[0101] Test Example 2: Weight Test
[0102] After the water maze experiment, the mice in each group rested for 30 minutes, and then were placed in a swimming box with a water depth of 30 cm and a water temperature of 25°C after a lead sheet of 5% of their body weight was loaded on their tails. The time from the start of automatic swimming to the head being completely submerged in the water and unable to float to the surface for 8 seconds was recorded as the weighted swimming time of the mice. The results are shown in Table 1.
[0103] Table 1
[0104]
[0105]
[0106] The test results show that the product prepared by the present invention can significantly prolong the weight-bearing swimming time of mice and alleviate the impact of high temperature on the experimental subjects.
[0107] As can be seen from the above embodiments, the present invention provides a water-salt supplement for high temperature environment and its application, including the following raw materials in parts by weight: 40-45 parts of sodium chloride, 12.5-16.5 parts of potassium chloride, 13-15 parts of calcium gluconate, 1.3-1.6 parts of magnesium citrate, 0.3-0.4 parts of zinc gluconate, 0.02-0.03 parts of vitamin B1, 0.01-0.02 parts of vitamin B2, and 0.01-0.02 parts of vitamin B6. The water-salt supplement of the present invention has a wide range of raw materials and a reasonable formula. It can be prepared into solid beverages, liquid beverages or salt pills and other products in various forms to quickly supplement the substances needed by the human body in a high temperature environment. At the same time, it can be prepared into various flavors such as sweet and salty, sugar-containing products and "zero sugar" products as needed to meet the needs of different groups of people.
[0108] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.
Claims
1. A water-salt supplement for use in high temperature environments, characterized in that: The invention comprises the following raw materials in parts by weight: 40-45 parts of sodium chloride, 12.5-16.5 parts of potassium chloride, 13-15 parts of calcium gluconate, 1.3-1.6 parts of magnesium citrate, 0.3-0.4 parts of zinc gluconate, 0.02-0.03 parts of vitamin B1, 0.01-0.02 parts of vitamin B2 and 0.01-0.02 parts of vitamin B6.
2. The water-salt supplement according to claim 1, characterized in that: The water-salt supplement also includes a sweetener, which is a low-intensity sweetener or a high-intensity sweetener.
3. The water-salt supplement according to claim 1, characterized in that: When the sweetener is a low-intensity sweetener, the added amount of the sweetener is 100 to 300 parts, and the low-intensity sweetener includes glucose, fructose, sucrose, maltose, starch sugar, xylitol, maltitol or erythritol.
4. The water-salt supplement according to claim 1, characterized in that: When the sweetener is a high-intensity sweetener, the added amount of the sweetener is 0.5 to 1 part, and the high-intensity sweetener includes sucralose, stevioside or mogroside.
5. The water-salt supplement according to claim 1, characterized in that: The water-salt supplement also includes DHA and EPA, the mass ratio of DHA to EPA is 2-3:5-7, and the added amount of DHA and EPA is 0.5-0.8 parts.
6. Use of the water-salt supplement according to any one of claims 1 to 5 in the preparation of a water-salt supplement product for use in a high temperature environment.
7. The use according to claim 6, characterized in that: The product includes a solid beverage, a liquid beverage or a salt pill.
8. The use according to claim 7, characterized in that When the product is a solid beverage, the water-salt supplement according to any one of claims 1 to 5 is diluted with water and then drunk, and the mass ratio of the water-salt supplement to water is 1:20-140.
9. The use according to claim 7, characterized in that When the product is a liquid beverage, it is obtained by compounding the water-salt supplement described in any one of claims 1 to 5 with water, and the mass ratio of the water-salt supplement to water is 1:20 to 140.
10. The use according to claim 7, characterized in that When the product is in the form of salt pills, it can be taken directly, and an appropriate amount of water can be drunk after taking it.