Full-automatic pre-dilution sample scheduling system and method for blood analyzer

Abstract

The invention relates to the technical field of medical treatment, in particular to a full-automatic pre-dilution sample scheduling system and method for a blood analyzer, and the method comprises the following steps: using a pre-dilution test tube rack by INC, starting multi-sample injection liquid discharge, selecting liquid discharge amount, and carrying out automatic pre-dilution liquid discharge operation; the IPU starts multi-sample introduction, and the pre-dilution test tube rack is placed on a sample introduction rack for automatic pre-dilution counting; the INC control software outputs a pre-dilution sample result, the sample result is uploaded to the IPU, and then the pre-dilution test tube rack is recycled. The method realizes multi-sample injection automatic testing of the pre-dilution sample, and can directly select the liquid discharge amount during multi-sample injection liquid discharge, and solves the problems that the pre-dilution sample cannot be automatically injected, each sample needs manual emergency treatment operation, and the operation efficiency is high. The problem of sample overstocking is solved, a full-automatic blood analysis system is more suitable for actual user requirements, the use complexity of a user is reduced, doctors are helped to more easily adapt to equipment, the learning cost is reduced, the automation degree is improved, and the human cost input is reduced.

Description

Technical Field

[0001] The present invention relates to the field of medical technology, and in particular to a fully automatic pre-dilution sample scheduling system and method for a blood analyzer. Background Art

[0002] When doctors need to perform pre-dilution counting, they usually need to manually drain the liquid and control the amount of liquid drained according to the number of times the liquid is drained. Each pre-dilution test tube test is performed in a single injection form. This mode requires pre-dilution draining first, and then pre-dilution counting. Too many manual operations make the process very cumbersome. When the sample size is large (such as maternal and child hospitals and children's hospitals), more manual intervention is required, resulting in slow testing speed and sample backlog. Summary of the invention

[0003] The purpose of the present invention is to provide a fully automatic pre-dilution sample scheduling system and method for a blood analyzer, aiming to solve the problem of sample backlog when the sample volume is large in the existing manual pre-dilution counting.

[0004] To achieve the above object, in a first aspect, the present invention provides a method for scheduling fully automatic pre-dilution samples of a blood analyzer, comprising the following steps:

[0005] INC uses the pre-dilution test tube rack, starts multi-injection dispensing, selects the dispensing volume, and performs automatic pre-dilution dispensing operations;

[0006] IPU starts multi-injection, and puts the pre-dilution test tube rack into the injection rack for automatic pre-dilution counting;

[0007] The INC control software outputs the pre-dilution sample result, uploads the sample result to the IPU, and then recycles the pre-dilution test tube rack.

[0008] The specific method of the INC using a pre-dilution test tube rack, starting multiple injection and discharging, selecting the discharging volume, and performing automatic pre-dilution and discharging operation is as follows:

[0009] INC places the test tubes that need to be drained on the pre-dilution test tube rack;

[0010] The pre-dilution test tube rack is placed on the automatic sample introduction plate, the multi-sample injection and liquid discharge are started, the liquid discharge volume is selected, and the fully automatic pre-dilution liquid discharge is started.

[0011] The specific method of the IPU starting multiple injections and placing the pre-dilution test tube rack on the injection rack for automatic pre-dilution counting is as follows:

[0012] IPU starts multi-injection and places the pre-dilution test tube rack on the injection rack;

[0013] The INC scans the barcode of the pre-dilution test tube rack to read information, registers the test tube rack with the IPU, reads the barcode information, and registers the test tube with the IPU to obtain the test tube information;

[0014] The INC applies for counting from the IPU based on the test tube information.

[0015] In a second aspect, the present invention further provides a fully automatic pre-dilution sample scheduling system for a blood analyzer, which is applied to the fully automatic pre-dilution sample scheduling method for a blood analyzer as described in the first aspect above, and is characterized in that:

[0016] It includes a test tube, a test tube rack identification device, a test tube presence identification device, a code scanning device, an inversion mixing device, an emergency chamber, a sampling needle and an automatic sampling mechanism, the code scanning device is arranged on one side of the automatic sampling mechanism, the test tube presence identification device is arranged on the side of the automatic sampling mechanism close to the code scanning device, the test tube rack identification device is arranged on the top of the automatic sampling mechanism, the emergency chamber is arranged on the side of the code scanning device away from the test tube presence identification device, the sampling needle is arranged on one side of the emergency chamber, and the test tube is arranged between the test tube rack identification device and the test tube presence identification device.

[0017] Wherein, the test tube presence identification device is a reflective optical coupling device.

[0018] The fully automatic pre-dilution sample scheduling method for a blood analyzer of the present invention comprises the following steps: INC uses a pre-dilution test tube rack, starts multi-injection and drainage, selects the drainage volume, and performs automatic pre-dilution and drainage operation; IPU starts multi-injection, and places the pre-dilution test tube rack on the injection rack for automatic pre-dilution counting; the INC control software outputs the pre-dilution sample result, and uploads the sample result to the IPU, and then recycles the pre-dilution test tube rack. The method realizes multi-injection automatic testing of pre-dilution samples, and at the same time solves the problem that users need to frequently perform manual pre-dilution drainage to meet the pre-dilution requirement during the previous single-injection pre-dilution test. The drainage volume can be directly selected during multi-injection and drainage, which solves the problem that pre-dilution samples cannot be automatically injected, each sample requires manual emergency operation, and the sample backlog is solved. The pre-dilution test speed is greatly improved, the fully automatic blood analysis system is more in line with the needs of actual users, the user's use complexity is reduced, and doctors are more easily adapted to the equipment, and the learning cost is reduced, the automation is improved, the human cost investment is reduced, and the existing manual pre-dilution counting and the sample backlog when the sample volume is large are solved. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0020] Figure 1 The present invention provides a flow chart of a method for scheduling fully automatic pre-dilution samples for a blood analyzer.

[0021] Figure 2 The present invention provides a flow chart of the fully automatic pre-dilution sample scheduling method for a blood analyzer.

[0022] Figure 3 This is a flowchart of the specific method of INC using the pre-dilution test tube rack, starting multiple injection and discharging, selecting the discharging volume, and performing automatic pre-dilution and discharging operations.

[0023] Figure 4 It is a flowchart of the specific method of IPU starting multiple injections and placing the pre-dilution test tube rack on the injection rack for automatic pre-dilution counting.

[0024] Figure 5 It is a structural diagram of the scheduling system.

[0025] Figure 6 is a schematic diagram of a test tube and test tube rack identification device.

[0026] Figure 7 It is a schematic diagram of whether the test tube has an identification device.

[0027] Figure 8 It is a schematic diagram of a code scanning device.

[0028] Fig. 9 is a schematic diagram of the inversion mixing device.

[0029] In the figure: 1-test tube, 2-test tube rack identification device, 3-test tube presence identification device, 4-code scanning device, 5-inversion mixing device, 6-emergency chamber, 7-sampling needle, 8-automatic sampling mechanism. DETAILED DESCRIPTION

[0030] Embodiments of the present invention are described in detail below, examples of which are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, and should not be construed as limiting the present invention.

[0031] See also Figures 1 to 4In a first aspect, the present invention provides a method for scheduling fully automatic pre-dilution samples of a blood analyzer, comprising the following steps:

[0032] S1INC uses a pre-dilution test tube rack, starts multi-injection dispensing, selects the dispensing volume, and performs automatic pre-dilution dispensing operations;

[0033] Specific method:

[0034] S11INC Place the test tube 1 that needs to be drained on the pre-dilution test tube rack;

[0035] S12: placing the pre-dilution test tube rack on the automatic sample introduction plate, starting the multi-sample injection and discharging, selecting the discharging volume, and starting the fully automatic pre-dilution and discharging.

[0036] S2IPU starts multi-injection and puts the pre-dilution test tube rack into the injection rack for automatic pre-dilution counting;

[0037] Specific method:

[0038] S21IPU starts multi-injection and places the pre-dilution test tube rack on the injection rack;

[0039] S22: the INC scans the barcode of the pre-dilution test tube rack to read information, registers the test tube rack with the IPU, reads the barcode information, and registers test tube 1 with the IPU to obtain information of test tube 1;

[0040] S23 The INC applies for counting from the IPU based on the information of test tube 1.

[0041] S3: The INC control software outputs the pre-dilution sample result, uploads the sample result to the IPU, and then recycles the pre-dilution test tube rack.

[0042] See also Figures 5 to 9 In a second aspect, the present invention further provides a fully automatic pre-dilution sample scheduling system for a blood analyzer, which is applied to the fully automatic pre-dilution sample scheduling method for a blood analyzer as described in the first aspect above, and is characterized in that it includes a test tube 1, a test tube rack identification device 2, a test tube presence identification device 3, a code scanning device 4, an inversion mixing device 5, an emergency chamber 6, a sampling needle 7 and an automatic sampling mechanism 8, wherein the code scanning device 4 is arranged on one side of the automatic sampling mechanism 8, the test tube presence identification device 3 is arranged on the side of the automatic sampling mechanism 8 close to the code scanning device 4, the test tube rack identification device 2 is arranged on the top of the automatic sampling mechanism 8, the emergency chamber 6 is arranged on the side of the code scanning device 4 away from the test tube presence identification device 3, the sampling needle 7 is arranged on one side of the emergency chamber 6, and the test tube 1 is arranged between the test tube rack identification device 2 and the test tube presence identification device 3.

[0043] In the embodiment of the present invention, the test tube 1 is an empty test tube in the drainage stage, and finally drains under the sampling needle 7 and returns to the outside of the instrument; in the test stage, the test sample (mixture of diluent and sample) is loaded and finally sampled under the sampling needle 7 for subsequent testing (the same process as the conventional test), and the test tube rack identification device 2 is affixed with an RFID tag on the edge of the test tube rack. The test tube rack identification device 2 reads the content in the tag through RFID technology to determine the type of the test tube 1 in the test tube rack where the sample is located. In this process, it is necessary to determine whether the type of the current test tube rack is a pre-dilution test tube rack. Only test tube racks that meet the conditions will continue the process, otherwise they will be pushed out of the automatic injection area. The test tube presence identification device 3 is a reflective optical coupling device. The light is irradiated onto the reflector and then reflected back to the receiver. Each test tube position of the test tube rack passes through the light path in turn. When there is a test tube 1, the light is blocked and cannot be irradiated onto the receiver. It can be realized to detect whether there is a test tube 1 on the test tube position on the test tube rack, and prepare for whether drainage or mixing test is required. The code scanning device 4 rotates the test tube 1 through a motor and its roller, and its scanner identifies the barcode or QR code information on the test tube 1, so that the instrument control unit can obtain LIS information and obtain the test mode requested by the clinician, so as to match the test results with the patient. In this process, there is no need to scan the code during the automatic discharge process, and the automatic discharge process is directly carried out. After the sample is loaded, the automatic pre-dilution process will be carried out, and an instruction will be sent to the code scanning device 4 to perform the code scanning action. The inversion and mixing device 5 is equipped with a test tube clamp, which can clamp the test tube 1 on the test tube rack and move it upward. When the emergency bin 6 moves under the test tube clamp, according to the current sample mode, it is determined to place the test tube 1 in the corresponding position in the emergency bin 6. In this process, the test tube 1 is placed in the test tube vibration mixing position; in other counting modes, the test tube clamp can be rotated to achieve the inversion and mixing of conventional venous whole blood.

[0044] The height of the test tube 1 is the same as that of an ordinary venous blood test tube. By using the test tube 1, a unified barcode label can be achieved with a commonly used venous whole blood test tube, which is convenient for the instrument to read the sample barcode. At the same time, the test tube 1 can be used for puncture by the sampling needle 7 to achieve automatic liquid discharge and puncture sample aspiration without opening the cover. The test tube rack moves to the left to inject samples and reaches the test tube identification position of the test tube identification device 3. When it detects that the test tube 1 has passed, the test tube 1 at this position will move to the left. When it reaches the test tube barcode reading position, the rotation of the test tube 1 and the movement of reading the barcode of the test tube 1 are started. Otherwise, the barcode reading action of test tube 1 will not be started. The emergency room 6 is equipped with a bullet-shaped test tube position, a conventional test tube and peripheral blood, and a test tube vibration mixing position. Under this scheduling logic, the mixing device will put the test tube in the peripheral blood and test tube vibration mixing position. After mixing, the test tube 1 can be transported to the sampling needle 7. During the drainage process, the diluent is added to the empty test tube 1 through the sampling needle 7. During the test process, the quantitative sample is drawn from the test tube 1 through the sampling needle 7 and distributed to each test module of the blood cell analyzer to complete the sample test. The automatic sampling mechanism 8 realizes the functions of pushing the test tube rack from the automatic sampling tray on the right to the test tube rack identification position, the test tube 1 passes through the test tube presence identification device 3 in turn, the test tube 1 passes through the code scanning device 4 in turn, the test tube 1 passes through the mixing position in turn, and the test tube rack is pushed out from the left sample tray.

[0045] The specific automatic pre-dilution discharge process is as follows:

[0046] First, place the tube that needs to be drained on the pre-dilution test tube rack, then put it on the automatic sampling tray, click the start draining button on the screen, select the draining amount, and start the fully automatic pre-dilution draining. The automatic sampling mechanism 8 will push the test tube rack to the test tube rack identification device 2, and read the test tube rack number information on the running test tube rack through the test tube rack number identification device. Only when the test tube rack number information is correct and meets the pre-dilution test tube rack, the subsequent fully automatic pre-dilution draining process action is allowed, otherwise the test tube rack type error message will be reported. After passing, the automatic sampling mechanism 8 will continue to push the test tube rack horizontally through the test tube presence or absence identification position, and use the test tube presence or absence identification device 3 to identify whether the test tube rack passing to the left has the test tube 1 placed at this position. Only when the test tube 1 is identified at this position, the subsequent functions of rotating the test tube and reading the test tube barcode information will be turned on. The test tube 1 is rotated by the test tube rotation driving wheel, so that the test tube 1 at the test tube barcode reading position can rotate several times, so that the barcode on the test tube 1 can face the barcode reader and be recognized. After the automatic sampling mechanism 8 continues to push the test tube rack to the mixing position, it decides whether to perform the mixing action according to whether the test tube 1 has information recorded in the previous test tube identification position. After the mixing action is completed, the needle puncture and the collection of pre-dilution samples will continue; otherwise, it will continue to push horizontally to test the next test tube 1. The function of pushing the test tube rack forward out of the station is realized by the test tube rack exit lever. When the test tube rack runs to the leftmost area of ​​the tray, it means that the automatic pre-dilution process of the current pre-dilution test tube rack is completed.

[0047] In order to better understand the present technical solution, the following embodiments are provided for further explanation:

[0048] In this embodiment, the fully automatic pre-dilution sample scheduling method of the blood analyzer is explained from the actual use of automatic pre-dilution.

[0049] Step 1: Start the fully automatic pre-dilution and discharge process;

[0050] The user needs to place the test tube 1 that needs to be pre-diluted in the test tube rack, and put the test tube rack into the automatic sample tray;

[0051] Click Start Draining on the main screen interface, select the amount to be drained, and then start the fully automatic pre-dilution drainage;

[0052] After the sampling mechanism on the INC control instrument determines that a test tube rack has entered, it will automatically run and push the test tube rack backwards to reach the test tube rack identification device 2; when the test tube rack identification device 2 recognizes that the information on the test tube rack is the correct pre-dilution test tube rack, the sampling mechanism will automatically push the test tube rack to the left; when the test tube rack runs to the test tube presence or absence identification position, the test tube 1 presence or absence identification optical coupler will start detection, and this position detects whether the test tube 1 has passed and determines whether the subsequent mixing position starts the mixing mechanism to clamp the test tube 1 and put it into the peripheral blood and pre-dilution position of the emergency bin 6 for pre-dilution and drainage; when the test tube presence or absence identification position detects the existence of the test tube 1 and runs to the test tube barcode reading position to the left, it is now fully automatic pre-dilution and drainage, and there is no need to scan the code, and it continues to advance to the mixing position. According to the test tube presence or absence information identified by the test tube identification position, the mixing mechanism on the INC control instrument clamps the test tube 1 and puts it into the pre-dilution position of the emergency bin 6 for pre-dilution and drainage operation. After the discharge is completed, the mixing mechanism will clamp the test tube 1 and put it back into the test tube rack. The INC controls the instrument to continue to push the test tube rack to the left to perform the pre-dilution and discharge operation on the next test tube 1. After all the test tubes 1 on the test tube rack where the test tube 1 is placed have completed the pre-dilution and discharge process, the sampling mechanism pushes the test tube rack to the out-of-rack area, and the fully automatic pre-dilution and discharge process ends.

[0053] Step 2: Fully automatic pre-dilution test;

[0054] The user needs to place the pre-diluted sample on the pre-dilution test tube rack, and place the pre-dilution test tube rack into the automatic sample tray;

[0055] IPU starts multi-injection test;

[0056] When INC receives the command from IPU to start multiple injections, the injection mechanism on the INC control instrument determines that a test tube rack has entered, and it will automatically run and push the test tube rack backwards to the rearmost area of ​​the tray; when the test tube rack number reader recognizes that the information on the test tube rack is the correct pre-dilution test tube rack, the injection mechanism will automatically push the test tube rack to the left; when the test tube rack runs to the test tube presence or absence identification position, the test tube presence or absence identification optical coupler will start the detection, and this position detects whether there is a test tube 1 passing through, which determines whether to subsequently start the barcode reader for barcode scanning, and whether the mixing position starts the mixing structure to clamp the test tube 1 and put it into the emergency chamber 6 for mixing operation; when the test tube presence or absence identification position detects that the test tube 1 exists and runs to the left to the test tube barcode reading position, the injection mechanism on the INC control instrument will start the test tube rotation active wheel and the barcode reader, and automatically scan the barcode information on the test tube 1. After the scanning is completed, the barcode reader will send the barcode number to the INC control software;

[0057] The INC control software actively inquires the IPU software whether the test tube 1 with the barcode on the test tube rack is to be tested for samples based on the scanned barcode number. After receiving the inquiry, the IPU software determines whether the test tube rack is a pre-dilution test tube rack. If it is a pre-dilution test tube rack, it replies whether to perform the test and the specific test mode. After the INC control software receives the reply from the IPU software, if a test is required, the test mode of the test tube 1 is recorded. When the test tube 1 is pushed to the mixing position, the INC control software starts the mixing mechanism to clamp the test tube 1 and put it into the emergency chamber 6 for mixing. After the mixing is completed, INC starts the pre-dilution sample test according to the recorded test mode;

[0058] Step 3: After INC completes the test of the pre-dilution sample, it uploads the test results to the IPU software. After the IPU receives the data and identifies it as the pre-dilution result, it displays the results uploaded by INC on the IPU end. Users can view the test results and test charts of the corresponding samples through the IPU software.

[0059] Step 4. After all the test tubes 1 on the pre-dilution test tube rack with the pre-diluted samples have completed the test process, the sampling mechanism pushes the test tube rack to the out-of-rack area. The out-of-rack area of ​​the sampling mechanism will push the test tube rack to the designated position for applying to exit the test tube rack. Once the test tube rack is detected at this position, the INC control software will send a request to the IPU software to perform scheduling planning for the test tube rack. After receiving the scheduling request, the IPU software will issue a corresponding scheduling reply to the INC control software. The INC control software determines whether the test tube rack is allowed to be pushed to the return track based on the received scheduling reply. If allowed, the INC control software controls the sampling mechanism to push the test tube rack out, and the fully automatic pre-dilution test process ends.

[0060] The above disclosure is only a preferred embodiment of the fully automatic pre-dilution sample scheduling system and method for the blood analyzer of the present invention. Of course, this cannot be used to limit the scope of rights of the present invention. Ordinary technicians in this field can understand that all or part of the processes of the above embodiments are implemented, and equivalent changes made according to the claims of the present invention still fall within the scope of the invention.

Claims

1. A method for scheduling fully automatic pre-dilution samples for a blood analyzer, characterized in that: The following steps are involved: INC uses the pre-dilution test tube rack, starts multi-injection dispensing, selects the dispensing volume, and performs automatic pre-dilution dispensing operations; IPU starts multi-injection, and puts the pre-dilution test tube rack into the injection rack for automatic pre-dilution counting; The INC control software outputs the pre-dilution sample result, uploads the sample result to the IPU, and then recycles the pre-dilution test tube rack.

2. The method for scheduling fully automatic pre-dilution samples for a blood analyzer according to claim 1, characterized in that: The specific method of the INC using the pre-dilution test tube rack, starting the multi-injection discharge, selecting the discharge volume, and performing the automatic pre-dilution discharge operation is as follows: INC places the test tubes that need to be drained on the pre-dilution test tube rack; The pre-dilution test tube rack is placed on the automatic sample introduction plate, the multi-sample injection and liquid discharge are started, the liquid discharge volume is selected, and the fully automatic pre-dilution liquid discharge is started.

3. The method for scheduling fully automatic pre-dilution samples for a blood analyzer according to claim 1, characterized in that: The specific method of the IPU starting multiple injections and placing the pre-dilution test tube rack on the injection rack for automatic pre-dilution counting is as follows: IPU starts multi-injection and places the pre-dilution test tube rack on the injection rack; The INC scans the barcode of the pre-dilution test tube rack to read information, registers the test tube rack with the IPU, reads the barcode information, and registers the test tube with the IPU to obtain the test tube information; The INC applies for counting from the IPU based on the test tube information.

4. A fully automatic pre-dilution sample scheduling system for a blood analyzer, applied to a fully automatic pre-dilution sample scheduling method for a blood analyzer as claimed in any one of claims 1 to 3, characterized in that: It includes a test tube, a test tube rack identification device, a test tube presence identification device, a code scanning device, an inversion mixing device, an emergency chamber, a sampling needle and an automatic sampling mechanism, the code scanning device is arranged on one side of the automatic sampling mechanism, the test tube presence identification device is arranged on the side of the automatic sampling mechanism close to the code scanning device, the test tube rack identification device is arranged on the top of the automatic sampling mechanism, the emergency chamber is arranged on the side of the code scanning device away from the test tube presence identification device, the sampling needle is arranged on one side of the emergency chamber, and the test tube is arranged between the test tube rack identification device and the test tube presence identification device.

5. The fully automatic pre-dilution sample scheduling system for a blood analyzer as claimed in claim 4, characterized in that: The test tube presence identification device is a reflective optical coupling device.

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