Kit for safely storing CTLA-4 antibody composition

Abstract

The invention discloses a kit for safely storing a CTLA-4 antibody composition, and particularly relates to the technical field of reagent storage.The kit is provided with a protection box body, a bearing plate, a bearing seat, a piston frame, a piston plate, a vertical rod, a contact ball, a telescopic air cylinder, a movable frame, an extension contact frame and a movable clamping plate, and the size of a placement hole is larger than that of a test tube; a test tube can be easily and smoothly placed in a placing hole, then an overturning protection cover is closed, the overturning protection cover extrudes a contact ball and a vertical rod to move, a piston plate can extrude gas in a piston frame to be transferred into a telescopic air cylinder when moving, the telescopic air cylinder extends to control a movable frame to act, and the movable frame extrudes an extension contact frame and a movable clamping plate to act while moving; the movable clamping plate is clamped on the surface of the test tube, so that the test tube is stably and smoothly clamped, whether the test tube is clamped and positioned or not is controlled by opening and closing the turnover protective cover, the test tube is taken and placed more smoothly and conveniently, and the stability of the test tube placed in the closed protective box body is better.

Description

Technical Field

[0001] The present invention relates to the technical field of reagent storage, and more specifically, to a kit for safely storing a CTLA-4 antibody composition. Background Art

[0002] The storage of antibody composition reagents requires that the test tube containing the antibody composition be placed in the corresponding test kit to achieve storage and certain protection functions. The test kits are mostly preset with designated hole structures, and the test tube is inserted into the hole. In order to ensure the stable placement of the test tube, the size of the hole will be set to correspond to the size of the test tube, which may result in the inability to accurately insert the test tube into the hole in one go when manually controlled. After the test tube is placed in, the test tube will shake significantly due to the transportation of the test kit and may even collide with the box wall, affecting the safety of the test tube placement. Therefore, a test kit for the safe storage of CTLA-4 antibody compositions is needed to solve the above problems. Summary of the invention

[0003] In order to overcome the above defects, the present invention provides a kit for safely storing a CTLA-4 antibody composition. The technical problem to be solved by the present invention is that when the test tubes are placed in the kit, in order to ensure the relative stability of the test tubes, the test tubes cannot be taken or placed conveniently and smoothly. At the same time, the test tubes may be damaged due to shaking during transportation.

[0004] To achieve the above-mentioned purpose, the present invention provides the following technical scheme: A kit for safely storing a CTLA-4 antibody composition, comprising a protective box body, a flip protective cover hingedly connected to the protective box body by a hinge, a carrying plate slidably arranged in the protective box body, a buffer control device connected to the protective box body, the carrying plate slidably connected to the outside of the buffer control device, a connecting pipe connected to the outside of the buffer control device, a mobile extrusion device connected under the carrying plate, the other end of the connecting pipe is connected to the mobile extrusion device, a guide groove is opened under the carrying plate, a clamping limit device is slidably connected in the guide groove, the mobile extrusion device is connected to the outside of the clamping limit device, a mobile positioning device is connected under the carrying plate, the mobile extrusion device is connected to the outside of the mobile positioning device, a positioning groove is opened in the protective box body, the mobile positioning device is connected in the positioning groove, an elastic buffer device is connected under the carrying plate, the elastic buffer device is connected in the protective box body, and a temperature control component is arranged in the protective box body.

[0005] As a further solution of the present invention: a sealing strip is connected to the protection box body, a placement hole is opened on the support plate, and a rubber ring is connected to a position on the support plate corresponding to the placement hole.

[0006] As a further solution of the present invention: two extension rods are connected to the positions corresponding to the placement holes under the supporting plate, and the two extension rods are externally connected to the same supporting seat, the position of the supporting seat corresponds to the position of the placement holes, and the side of the supporting seat close to the supporting plate is set to an arc shape.

[0007] As a further solution of the present invention: the buffer control device includes a piston frame, the piston frame is connected inside the protection box body, the piston frame is slidably connected outside the bearing plate, a piston plate is slidably connected inside the piston frame, the piston plate is set to a rectangle, and the piston frame is connected to the connecting pipe.

[0008] As a further solution of the present invention: a vertical rod is connected to the piston plate, a sliding connecting sleeve is slidably connected to the outside of the vertical rod, the sliding connecting sleeve is connected to the piston frame, a contact ball is connected to the top of the vertical rod, a first elastic component is connected under the piston plate, and the other end of the first elastic component is connected to the piston frame.

[0009] As a further solution of the present invention: the mobile extrusion device includes a telescopic gas cylinder, the telescopic gas cylinder is connected to a connecting pipe, the telescopic gas cylinder is connected under a bearing plate, the bottom end of the telescopic gas cylinder is connected to a mobile frame, and the mobile frame is provided with two mobile inclined parts.

[0010] As a further solution of the present invention: the clamping and limiting device includes a movable clamping plate, the movable clamping plate is externally connected to an extension contact frame, the extension contact frame is connected to the outside of the mobile extrusion device, the extension contact frame is connected to a guide block, the guide block is slidably connected in a guide groove, the guide block is externally connected to a second elastic component, the other end of the second elastic component is connected to the guide groove, the guide block is configured to be T-shaped, and the side close to two adjacent movable clamps is configured to be arc-shaped.

[0011] As a further solution of the present invention: the mobile positioning device includes a mobile seat, the mobile seat is provided with an inclined extrusion groove, the inclined extrusion groove is connected to the mobile extrusion device, and a transverse positioning rod is connected to the side of the mobile seat away from the supporting seat, and the other end of the transverse positioning rod is arranged in the positioning groove.

[0012] As a further solution of the present invention: the outer sleeve of the transverse positioning rod is provided with a guide sleeve, the guide sleeve is connected to a fixing rod, the fixing rod is connected under the bearing plate, the outer sleeve of the transverse positioning rod is provided with a third elastic component, one end of the third elastic component is connected to the moving seat, and the other end of the third elastic component is connected to the guide sleeve.

[0013] As a further solution of the present invention: the elastic buffer device includes a telescopic rod, one end of the telescopic rod is connected to the bearing plate, the other end of the telescopic rod is connected to the protective box body, the outer sleeve of the telescopic rod is provided with a fourth elastic component, one end of the fourth elastic component is connected to the bearing plate, and the other end of the fourth elastic component is connected to the protective box body.

[0014] The beneficial effects of the present invention are:

[0015] 1. The present invention provides a protective box body, a bearing plate, a bearing seat, a piston frame, a piston plate, a vertical rod, a contact ball, a telescopic gas cylinder, a movable frame, an extended contact frame and a movable clamping plate. The size of the placement hole is larger than the test tube, and the test tube can be easily and smoothly placed in the placement hole. Then, the flip protective cover is closed, and the flip protective cover squeezes the contact ball and the vertical rod to move. When the piston plate moves, it squeezes the gas in the piston frame and transfers it to the telescopic gas cylinder, so that the telescopic gas cylinder is extended to control the movement of the movable frame. When the movable frame moves, it squeezes the extended contact frame and the movable clamping plate. The movable clamping plate is clamped on the surface of the test tube to achieve stable and smooth clamping of the test tube. The opening and closing of the flip protective cover is used to control whether the test tube is clamped and positioned, so that the test tube is taken and placed more smoothly and conveniently, and the test tube is placed in the closed protective box body with better stability.

[0016] 2. The present invention provides a movable frame, a telescopic air cylinder, an inclined extrusion groove, a transverse positioning rod, a positioning groove, a third elastic component and a fourth elastic component. When the flip protective cover is opened, the third elastic component applies elastic force to the transverse positioning rod to make it located in the positioning groove. At this time, the carrier plate remains stable in the protection box body, which can facilitate the taking and placing operations of the test tube in the placement hole. When the flip protective cover is closed, the movable frame moves downward to squeeze the inclined extrusion groove and the movable seat to move. At this time, the transverse positioning rod is separated from the positioning groove, and the contact between the carrier plate and the protection box body is limited. When the protection box body is vibrated, the fourth elastic component can provide buffering protection for the carrier plate in the protection box body to avoid large shaking of the carrier plate, and the buffering protection effect for the carrier plate and the test tube is better. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a three-dimensional structural schematic diagram of the present invention;

[0018] Figure 2 It is a three-dimensional structural schematic diagram of the protection box body of the present invention;

[0019] Figure 3 It is a schematic diagram of the three-dimensional cross-sectional structure of the protection box body of the present invention;

[0020] Figure 4 For the present invention Figure 3 The structural diagram of the enlarged part A in the middle;

[0021] Figure 5It is a three-dimensional structural schematic diagram of the carrying plate of the present invention;

[0022] Figure 6 It is a three-dimensional structural schematic diagram of the connecting pipe of the present invention;

[0023] Figure 7 It is a three-dimensional structural schematic diagram of the mobile extrusion device of the present invention;

[0024] Figure 8 It is a three-dimensional structural schematic diagram of the buffer control device of the present invention;

[0025] Fig. 9 It is a second three-dimensional structural schematic diagram of the mobile positioning device of the present invention;

[0026] Fig.10 It is a three-dimensional structural schematic diagram of the elastic buffer device of the present invention;

[0027] In the figure: 1, protective box body; 2, flip protective cover; 3, bearing plate; 4, placement hole; 5, rubber ring; 6, sealing strip; 7, buffer control device; 71, piston frame; 72, first elastic component; 73, piston plate; 74, vertical rod; 75, sliding connection sleeve; 76, contact ball; 8, connecting pipe; 9, mobile extrusion device; 91, telescopic air cylinder; 92, mobile frame; 93, mobile tilting part; 10, guide groove; 11, mobile positioning device; 111, Movable seat; 112, inclined extrusion groove; 113, transverse positioning rod; 114, guide sleeve; 115, fixed rod; 116, third elastic component; 12, positioning groove; 13, extension rod; 14, bearing seat; 15, elastic buffer device; 151, telescopic rod; 152, fourth elastic component; 16, temperature control component; 17, clamping limit device; 171, movable splint; 172, extension contact frame; 173, guide block; 174, second elastic component. DETAILED DESCRIPTION

[0028] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0029] like Figure 1-10As shown, the present invention provides a kit for safe storage of a CTLA-4 antibody composition, comprising a protective box body 1, a flip protective cover 2 is hinged to the outside of the protective box body 1 through a hinge, a carrying plate 3 is slidably provided in the protective box body 1, a buffer control device 7 is connected to the inside of the protective box body 1, the carrying plate 3 is slidably connected to the outside of the buffer control device 7, and a connecting pipe 8 is connected to the outside of the buffer control device 7. By providing the connecting pipe 8, the connecting pipe 8 realizes the communication between the buffer control device 7 and the mobile extrusion device 9, so that the gas flows between the two.

[0030] A mobile extrusion device 9 is connected under the carrying plate 3, and the other end of the connecting tube 8 is connected to the mobile extrusion device 9. A guide groove 10 is opened under the carrying plate 3, and a clamping limit device 17 is slidably connected in the guide groove 10. The mobile extrusion device 9 is connected to the outside of the clamping limit device 17. A mobile positioning device 11 is connected under the carrying plate 3, and the mobile extrusion device 9 is connected to the outside of the mobile positioning device 11. A positioning groove 12 is opened in the protection box body 1, and the mobile positioning device 11 is connected in the positioning groove 12. An elastic buffer device 15 is connected under the carrying plate 3, and the elastic buffer device 15 is connected in the protection box body 1. A temperature control component 16 is provided in the protection box body 1. By setting the temperature control component 16, the temperature in the protection box body 1 can be adjusted according to the required storage temperature of the antibody.

[0031] A sealing strip 6 is connected to the protection box body 1, a placement hole 4 is opened on the supporting plate 3, and a rubber ring 5 is connected to the position of the supporting plate 3 corresponding to the placement hole 4. By setting the rubber ring 5, obvious collision between the test tube and the supporting plate 3 during the lowering process is avoided. By setting the sealing strip 6, the sealing strip 6 is used to increase the sealing effect between the flip protective cover 2 and the protection box body 1.

[0032] Two extension rods 13 are connected to the positions corresponding to the placement holes 4 under the supporting plate 3, and the two extension rods 13 are externally connected to the same supporting seat 14. The position of the supporting seat 14 corresponds to the position of the placement hole 4, and the side of the supporting seat 14 close to the supporting plate 3 is set to an arc shape. By setting the extension rods 13 and the supporting seat 14, the supporting seat 14 can support the bottom of the test tube so that the test tube can be smoothly placed in the protective box body 1.

[0033] The buffer control device 7 includes a piston frame 71, which is connected to the protective box body 1. The piston frame 71 is slidably connected to the outside of the supporting plate 3. A piston plate 73 is slidably connected to the piston frame 71. The piston plate 73 is set to be rectangular. The piston frame 71 is connected to the connecting pipe 8. By setting the piston frame 71, the piston frame 71 cooperates with the piston plate 73, and the movement of the piston plate 73 can be used to squeeze out the gas in the piston frame 71 or suck in the external gas.

[0034] The piston plate 73 is connected to a vertical rod 74, and a sliding connection sleeve 75 is slidably connected to the outside of the vertical rod 74. The sliding connection sleeve 75 is connected to the piston frame 71, and the top of the vertical rod 74 is connected to a contact ball 76. The piston plate 73 is connected to a first elastic component 72, and the other end of the first elastic component 72 is connected to the piston frame 71. By setting the sliding connection sleeve 75, the sliding connection sleeve 75 guides the vertical rod 74 to ensure that the vertical rod 74 performs stable movement in the vertical direction. By setting the first elastic component 72, when the contact ball 76 is not in contact with the flip protective cover 2, the first elastic component 72 ensures that the vertical rod 74 and the piston plate 73 are stably in the upper position, and when the flip protective cover 2 is separated from the contact ball 76, the piston plate 73 is controlled to reset upward.

[0035] The mobile extrusion device 9 includes a telescopic gas cylinder 91, which is connected to the connecting pipe 8. The telescopic gas cylinder 91 is connected under the supporting plate 3. The bottom end of the telescopic gas cylinder 91 is connected to a mobile frame 92. The mobile frame 92 is provided with two mobile inclined parts 93. By setting the telescopic gas cylinder 91, the increase of the air pressure in the telescopic gas cylinder 91 will automatically extend the mobile frame 92 to move downward. The decrease of the air pressure in the telescopic gas cylinder 91 will shorten the mobile frame 92 and drive the mobile frame 92 to move upward. By setting the mobile frame 92 and the mobile inclined part 93, the inclined surface of the mobile inclined part 93 can be used to squeeze the clamping limit device 17 to act when the mobile inclined part 93 moves downward.

[0036] The clamping and limiting device 17 includes a movable clamping plate 171, the movable clamping plate 171 is externally connected to an extended contact frame 172, the extended contact frame 172 is connected to the outside of the movable extrusion device 9, the extended contact frame 172 is connected to a guide block 173, the guide block 173 is slidably connected in the guide groove 10, the guide block 173 is externally connected to a second elastic component 174, the other end of the second elastic component 174 is connected in the guide groove 10, the guide block 173 is set to be T-shaped, and the side close to two adjacent movable clamping plates 171 is set to be arc-shaped;

[0037] By setting a movable clamp 171, the two movable clamps 171 cooperate to achieve the clamping and limiting of the test tube, ensuring that the test tube is stably located in the placement hole 4 and the protective box body 1. By setting an extended contact frame 172, the side of the extended contact frame 172 close to the movable extrusion device 9 is set to an inclined state. When being squeezed by the movable extrusion device 9, it can perform a certain amplitude of horizontal movement. By setting a guide block 173 and a guide groove 10, the guide groove 10 guides the movement of the guide block 173 and the movable clamp 171. When the extended contact frame 172 is squeezed, the guide block 173 and the movable clamp 171 can smoothly move in a straight line in the horizontal direction. By setting a second elastic component 174, the second elastic component 174 can ensure that the movable clamp 171 will not shake at will. At the same time, when the movable extrusion device 9 moves away from the extended contact frame 172, the movable clamp 171 is controlled to move away from the test tube.

[0038] The mobile positioning device 11 includes a mobile seat 111, on which an inclined extrusion groove 112 is provided, and the inclined extrusion groove 112 is connected to the mobile extrusion device 9. A transverse positioning rod 113 is connected to the side of the mobile seat 111 away from the bearing seat 14, and the other end of the transverse positioning rod 113 is arranged in the positioning groove 12. By setting the mobile seat 111 and the inclined extrusion groove 112, when the mobile extrusion device 9 is actuated, the mobile seat 111 can be controlled to move in the horizontal direction through the inclined extrusion groove 112. By setting the transverse positioning rod 113 and the positioning groove 12, the transverse positioning rod 113 is located in the positioning groove 12, which can prevent the bearing plate 3 from shaking in the vertical direction in the protective box body 1. When the positioning groove 12 is separated from the transverse positioning rod 113, the bearing plate 3 can shake in the vertical direction in the protective box body 1.

[0039] The outer sleeve of the transverse positioning rod 113 is provided with a guide sleeve 114, the guide sleeve 114 is connected with a fixing rod 115, the fixing rod 115 is connected under the bearing plate 3, the outer sleeve of the transverse positioning rod 113 is provided with a third elastic component 116, one end of the third elastic component 116 is connected to the moving seat 111, and the other end of the third elastic component 116 is connected to the guide sleeve 114;

[0040] By setting the guide sleeve 114, the guide sleeve 114 guides the movement of the transverse positioning rod 113 and the movable seat 111, ensuring that the movable seat 111 and the transverse positioning rod 113 stably perform horizontal linear movement. By setting the third elastic component 116, when the mobile extrusion device 9 is separated from the inclined extrusion groove 112, the third elastic component 116 can control the transverse positioning rod 113 to automatically insert into the positioning groove 12, and at the same time ensure that the transverse positioning rod 113 remains stable in the positioning groove 12.

[0041] The elastic buffer device 15 includes a telescopic rod 151, one end of the telescopic rod 151 is connected to the supporting plate 3, and the other end of the telescopic rod 151 is connected to the protective box body 1. A fourth elastic component 152 is provided on the outer sleeve of the telescopic rod 151, one end of the fourth elastic component 152 is connected to the supporting plate 3, and the other end of the fourth elastic component 152 is connected to the protective box body 1. By setting the telescopic rod 151, the telescopic rod 151 ensures that the supporting plate 3 can perform small vertical movements in the protective box body 1. By setting the fourth elastic component 152, the fourth elastic component 152 is used to buffer the vertical shaking of the supporting plate 3 to avoid large shaking and collision of the test tube.

[0042] Working principle of the present invention:

[0043] When it is necessary to store the test tubes containing reagents, the test tubes are directly placed on the supporting seat 14 through the placement hole 4, and then the flip protective cover 2 is closed. The flip protective cover 2 is rotated while squeezing the contact ball 76 and the vertical rod 74 to move. The vertical rod 74 drives the piston plate 73 to move downward. When the piston plate 73 moves, it squeezes the gas in the piston frame 71 and transfers it to the telescopic gas cylinder 91 through the connecting pipe 8. The increased air pressure in the telescopic gas cylinder 91 controls its extension. The extension of the telescopic gas cylinder 91 controls the downward movement of the movable frame 92. While the movable frame 92 moves, it squeezes the extended gas. The extended contact frame 172 and the inclined extrusion groove 112 drive the movable clamping plate 171 to move, and the movable clamping plate 171 is clamped on the surface of the test tube to achieve stable and smooth clamping of the test tube. The inclined extrusion groove 112 is squeezed to control the movement of the movable seat 111 and the transverse positioning rod 113. After the transverse positioning rod 113 is separated from the positioning groove 12, it contacts the limit between the carrying plate 3 and the protection box body 1. When the protection box body 1 is collided during transportation, the fourth elastic component 152 buffers and protects the shaking of the carrying plate 3.

[0044] When the test tube needs to be removed, the flip protective cover 2 is directly opened. At this time, the contact ball 76 loses the squeezing of the flip protective cover 2, and the first elastic component 72 drives the piston plate 73 to move upward. The gas in the telescopic gas cylinder 91 is sucked into the piston frame 71 through the connecting pipe 8. The telescopic gas cylinder 91 shortens and drives the movable frame 92 to move upward. At this time, the movable frame 92 reduces the squeezing degree of the extended contact frame 172 and the inclined squeezing groove 112. The second elastic component 174 drives the guide block 173 and the movable splint 171 to separate from the test tube. At the same time, the third elastic component 116 drives the transverse positioning rod 113 to insert into the positioning groove 12 to achieve the limit between the carrier plate 3 and the protective box body 1, and then the test tube can be taken out from the placement hole 4.

[0045] Finally, a few points should be explained: First, in the description of this application, it should be noted that, unless otherwise specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, which may refer to mechanical connection or electrical connection, or internal communication between two components, or direct connection. "upper", "lower", "left", "right", etc. are only used to indicate relative positional relationships. When the absolute position of the object being described changes, the relative positional relationship may change;

[0046] Secondly: In the drawings of the embodiments disclosed in the present invention, only the structures related to the embodiments disclosed in the present invention are involved, and other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of the present invention can be combined with each other;

[0047] Finally: The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A kit for safe storage of a CTLA-4 antibody composition, comprising a protective box body (1), characterized in that: The protection box body (1) is hingedly provided with a flip protection cover (2) on the outside through a hinge, the protection box body (1) is slidably provided with a bearing plate (3), the protection box body (1) is connected with a buffer control device (7), the bearing plate (3) is slidably connected to the outside of the buffer control device (7), the buffer control device (7) is connected with a connecting pipe (8), the bearing plate (3) is connected to a movable extrusion device (9) under the bearing plate (3), and the other end of the connecting pipe (8) is connected to the movable extrusion device (9); A guide groove (10) is provided under the bearing plate (3), a clamping limit device (17) is slidably connected in the guide groove (10), the mobile extrusion device (9) is connected to the outside of the clamping limit device (17), a mobile positioning device (11) is connected under the bearing plate (3), the mobile extrusion device (9) is connected to the outside of the mobile positioning device (11), a positioning groove (12) is provided in the protection box body (1), the mobile positioning device (11) is connected in the positioning groove (12), an elastic buffer device (15) is connected under the bearing plate (3), the elastic buffer device (15) is connected in the protection box body (1), and a temperature control component (16) is provided in the protection box body (1).

2. A kit for safe storage of a CTLA-4 antibody composition according to claim 1, characterized in that: The protection box body (1) is connected to a sealing strip (6), the support plate (3) is provided with a placement hole (4), and a rubber ring (5) is connected to a position on the support plate (3) corresponding to the placement hole (4).

3. A kit for safe storage of a CTLA-4 antibody composition according to claim 1, characterized in that: Two extension rods (13) are connected to positions corresponding to the placement holes (4) under the bearing plate (3); the two extension rods (13) are externally connected to a same bearing seat (14); the position of the bearing seat (14) corresponds to the position of the placement holes (4); and the side of the bearing seat (14) close to the bearing plate (3) is set in an arc shape.

4. A kit for safe storage of a CTLA-4 antibody composition according to claim 1, characterized in that: The buffer control device (7) comprises a piston frame (71), the piston frame (71) is connected inside the protection box body (1), the piston frame (71) is slidably connected to the outside of the bearing plate (3), a piston plate (73) is slidably connected inside the piston frame (71), the piston plate (73) is set to be rectangular, and the piston frame (71) is connected to the connecting pipe (8).

5. A kit for safe storage of a CTLA-4 antibody composition according to claim 4, characterized in that: The piston plate (73) is connected to a vertical rod (74), the vertical rod (74) is slidably connected to a sliding connection sleeve (75), the sliding connection sleeve (75) is connected to the piston frame (71), the top of the vertical rod (74) is connected to a contact ball (76), the piston plate (73) is connected to a first elastic component (72) at the bottom, and the other end of the first elastic component (72) is connected to the piston frame (71).

6. A kit for safe storage of a CTLA-4 antibody composition according to claim 1, characterized in that: The mobile extrusion device (9) comprises a telescopic gas cylinder (91), the telescopic gas cylinder (91) is connected to the connecting pipe (8), the telescopic gas cylinder (91) is connected under the carrying plate (3), the bottom end of the telescopic gas cylinder (91) is connected to a mobile frame (92), and the mobile frame (92) is provided with two mobile inclined parts (93) outside.

7. A kit for safe storage of a CTLA-4 antibody composition according to claim 1, characterized in that: The clamping and limiting device (17) comprises a movable clamping plate (171), the movable clamping plate (171) is externally connected to an extended contact frame (172), the extended contact frame (172) is connected to the outside of the movable extrusion device (9), the extended contact frame (172) is connected to a guide block (173), the guide block (173) is slidably connected in a guide groove (10), the guide block (173) is externally connected to a second elastic component (174), the other end of the second elastic component (174) is connected in the guide groove (10), the guide block (173) is set to be T-shaped, and the side close to two adjacent movable clamping plates (171) is set to be arc-shaped.

8. A kit for safe storage of a CTLA-4 antibody composition according to claim 3, characterized in that: The movable positioning device (11) comprises a movable seat (111), an inclined extrusion groove (112) is provided on the movable seat (111), the inclined extrusion groove (112) is connected to the movable extrusion device (9), and a transverse positioning rod (113) is connected to a side of the movable seat (111) away from the bearing seat (14), and the other end of the transverse positioning rod (113) is arranged in the positioning groove (12).

9. A kit for safe storage of a CTLA-4 antibody composition according to claim 8, characterized in that: The outer sleeve of the transverse positioning rod (113) is provided with a guide sleeve (114), the guide sleeve (114) is connected with a fixing rod (115), the fixing rod (115) is connected under the bearing plate (3), the outer sleeve of the transverse positioning rod (113) is provided with a third elastic component (116), one end of the third elastic component (116) is connected to the moving seat (111), and the other end of the third elastic component (116) is connected to the guide sleeve (114).

10. A kit for safe storage of a CTLA-4 antibody composition according to claim 1, characterized in that: The elastic buffer device (15) comprises a telescopic rod (151), one end of the telescopic rod (151) is connected to the bearing plate (3), the other end of the telescopic rod (151) is connected to the protection box body (1), and a fourth elastic component (152) is provided on the outer sleeve of the telescopic rod (151), one end of the fourth elastic component (152) is connected to the bearing plate (3), and the other end of the fourth elastic component (152) is connected to the protection box body (1).

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