Collateral-dredging formula composition for infertility as well as application and preparation method of collateral-dredging formula composition

Abstract

The invention discloses a collateral dredging composition for infertility as well as application and a preparation method thereof. The composition is prepared from the following raw materials: fetus cervi glue, rhizoma atractylodis macrocephalae, codonopsis pilosula, astragalus membranaceus, angelica sinensis, radix rehmanniae preparata, spina gleditsiae, ligusticum wallichii, radix rehmanniae, semen brassicae, achyranthes bidentata, pericarpium citri reticulatae viride, pericarpium citri reticulatae, cistanche deserticola, herba epimedii, tortoise plastron, turtle shell and rhizoma cyperi. The invention also provides an application of the composition, and the composition is used for preparing a medicament for oral administration. The invention also provides a preparation method of the medicament. According to the collateral dredging composition for infertility and the application and the preparation method of the collateral dredging composition, the obtained composition has the effects of tonifying kidney, nourishing blood, reducing phlegm and dredging collaterals, adopts natural Chinese herbal medicine raw materials, is basically free of side effects, can treat both symptoms and root causes for infertility, especially polycystic ovarian infertility, is remarkable in clinical effect and is worthy of application and popularization.

Description

Technical Field

[0001] The present invention relates to a pharmaceutical composition for infertility, application and preparation method thereof, and in particular to a Tongluo prescription composition for infertility, application and preparation method thereof. Background Art

[0002] With the changes in modern people's lifestyle and dietary structure, many unhealthy effects have been produced, leading to a sharp increase in infertility. The medical definition of infertility is that no contraceptive measures have been taken for more than one year, and sexual life is normal but no successful pregnancy has occurred. It is mainly divided into primary infertility and secondary infertility. Primary infertility means that you have never conceived; secondary infertility means that you have been pregnant but then you are still infertile. According to this strict definition, infertility is a common problem that affects at least 10% to 15% of couples of childbearing age. The causes of infertility are divided into male infertility and female infertility, among which polycystic ovary syndrome is one of the causes of female infertility.

[0003] Polycystic Ovary Syndrome (PCOS) is the most common endocrine metabolic disease in women of childbearing age, and its causes may be related to genetic and environmental factors. PCOS can affect women of all ages. Female patients in adolescence and childbearing years mainly present with symptoms such as menstrual abnormalities, acne, hirsutism, and infertility. Middle-aged and elderly patients are more likely to develop problems such as diabetes, hyperlipidemia, and cardiovascular disease.

[0004] From the perspective of Western medicine, the pathological basis of infertility caused by polycystic ovary syndrome is that small follicles cannot develop and mature eggs are not released, and the patient's ovarian endometrium is thick and dense. Even if the egg is mature, it is difficult to break through, which ultimately leads to infertility.

[0005] From the perspective of traditional Chinese medicine, the key to solving polycystic ovary infertility is to nourish the kidneys and regulate menstruation to facilitate pregnancy. "Menstruation is not coming because of blocked uterine vessels." For polycystic ovary patients, in addition to kidney deficiency, pathological products such as phlegm and dampness and blood stasis are also important factors leading to late menstruation and amenorrhea.

[0006] Therefore, developing effective kidney-tonifying, blood-nourishing and collateral-draining drugs for PCOS will bring good news to female infertility patients. Summary of the invention

[0007] The purpose of the present invention is to provide a pharmaceutical composition for infertility and its use and preparation method, which can solve the existing problems, adopt a natural Chinese herbal medicine formula, cure the symptoms and the root cause, have basically no side effects, and have significant effects on symptoms such as infertility and uterine cold.

[0008] In order to achieve the above-mentioned purpose, the present invention provides a Tongluo prescription composition for infertility, wherein the raw materials of the composition include: deer placenta glue, Atractylodes macrocephala, Codonopsis pilosula, Astragalus membranaceus, Angelica sinensis, Rehmannia glutinosa, Gleditsia sinensis thorn, Chuanxiong, Rehmannia glutinosa, Sinapis alba, Achyranthes bidentata, Citrus reticulata, Cistanche deserticola, Epimedium, Tortoise shell, Turtle shell, and Cyperus rotundus.

[0009] The above-mentioned Tongluo prescription composition for infertility, wherein the raw materials of the composition, by weight, include: 8-12 parts of deer placenta glue, 14-16 parts of Atractylodes macrocephala, 12-15 parts of Codonopsis pilosula, 15-25 parts of Astragalus, 12-18 parts of Angelica sinensis, 10-13 parts of Rehmannia glutinosa, 9-15 parts of Gleditsia sinensis thorns, 10-12 parts of Chuanxiong, 14-16 parts of Rehmannia glutinosa, 12-15 parts of Sinapis alba, 10-12 parts of Achyranthes bidentata, 8-10 parts of Citrus reticulata, 8-10 parts of Citrus reticulata, 12-32 parts of Cistanche deserticola, 12-15 parts of Epimedium, 15-25 parts of Tortoise shell, 15-25 parts of Turtle shell, and 12-15 parts of Cyperus rotundus.

[0010] The above-mentioned Tongluo prescription composition for infertility, wherein the raw materials comprise by weight: 9g of deer placenta glue, 15g of Atractylodes macrocephala, 12g of Codonopsis pilosula, 20g of Astragalus, 12g of Angelica sinensis, 10g of Rehmannia glutinosa, 9g of Gleditsia sinensis, 12g of Ligusticum chuanxiong, 15g of Rehmannia glutinosa, 12g of Sinapis alba, 10g of Achyranthes bidentata, 9g of Citrus aurantium, 9g of Citrus reticulata, 12g of Cistanche deserticola, 12g of Epimedium, 15g of Tortoise shell, 15g of Turtle shell, and 12g of Cyperus rotundus.

[0011] The present invention also provides a use of the Tongluo prescription composition for infertility, wherein the composition is used to prepare an oral medicament.

[0012] The present invention also provides a method for preparing the above-mentioned medicine, wherein the method is: weigh each drug raw material in proportion, wash and dry the washable raw materials, then grind and crush all the raw materials, add water to boil, filter to obtain the medicinal solution, and divide it for use.

[0013] The preparation method of the above-mentioned medicine, wherein in the method described, when adding water for decoction, first use a low heat at 80°C for 35 minutes, and then use a high heat at 120°C for 40 minutes. After filtering, the obtained medicinal liquid is divided into small packets, each packet is 180g, and sealed and stored for later use.

[0014] The preparation method of the above-mentioned medicine, wherein in the method, a medicine decocting machine is used to decoct the Chinese medicine, and the Chinese medicine for 10 days is decocted at one time.

[0015] The preparation method of the above-mentioned medicament, wherein the liquid medicine is taken twice a day, one pack each in the morning and afternoon, and the temperature of the liquid medicine is controlled at 40°C during oral administration.

[0016] The Tongluo prescription composition for infertility provided by the present invention, its use and preparation method have the following advantages:

[0017] The composition of the present invention is a kidney-tonifying, blood-nourishing, phlegm-resolving and collateral-dredging prescription, which adopts natural Chinese herbal medicines, has substantially no side effects, and is effective in curing the root cause of polycystic ovarian infertility. The composition is based on the etiology and pathogenesis of kidney deficiency and phlegm and blood stasis, combined with the recognition of Western medicine on abnormal follicular development and ovulation disorders of the disease, and closely combines the traditional efficacy of the medicine with modern research, and creates a polycystic prescription with the main effects of kidney-tonifying, blood-nourishing, phlegm-resolving and collateral-dredging, and the prepared medicine can be used to treat infertile patients caused by PCOS. The prescription is very exquisite in medication, and the compatibility is scientific and rigorous, and a good clinical efficacy has been achieved. DETAILED DESCRIPTION

[0018] The specific embodiments of the present invention are further described below.

[0019] The invention provides a Tongluo prescription composition for infertility. The raw materials of the composition include: deer placenta glue, atractylodes macrocephala, codonopsis pilosula, astragalus, angelica sinensis, prepared rehmannia root, Gleditsia sinensis thorn, ligusticum chuanxiong, raw rehmannia root, white mustard seeds, cyathula officinalis, green peel, tangerine peel, Cistanche deserticola, epimedium, tortoise shell, turtle shell and cyperus rotundus.

[0020] Among them, deer placenta glue is also called deer placenta paste. This product is a brown to dark brown rectangular dry paste. It tastes sweet, slightly bitter, and warm in nature. It enters the liver and kidney meridians. The deer placenta is decocted, roasted, crushed, and boiled with other medicinal materials and brown sugar to make deer placenta paste. It has the effects of replenishing qi and blood, regulating menstruation and dispelling cold. It is used for insufficient qi and blood, weakness and emaciation, irregular menstruation, abdominal pain during menstruation, and leukorrhea caused by cold and dampness. It is mainly used to treat irregular menstruation, uterine cold and infertility, metrorrhagia and leukorrhea, kidney deficiency and weakness, tuberculosis, and hepatitis. Deer placenta paste is rich in amino acids, vitamins, calcium, iron, zinc and other elements, which have the effects of replenishing qi and blood, regulating menstruation, strengthening yang, replenishing deficiency, and beautifying the skin.

[0021] Atractylodes macrocephala belongs to the Asteraceae family and the genus Atractylodes. As a Chinese medicinal material, this product is the rhizome of Atractylodes macrocephala. It is dug from the beginning of winter to the beginning of winter, and the stems, leaves and soil are removed, and the roots are removed after drying or sun drying. It tastes bitter and sweet, and is warm in nature. It enters the spleen and stomach meridians. It has the functions of strengthening the spleen and replenishing qi, drying dampness and promoting diuresis, stopping sweating, and calming the fetus. It is used for spleen deficiency, poor appetite, abdominal distension and diarrhea, phlegm and fluid, palpitations, edema, spontaneous sweating, and restless fetuses.

[0022] Codonopsis is the dried root of Codonopsis pilosula, Codonopsis pilosula, or Codonopsis pilosula of the Campanulaceae family. It is sweet and flat in nature, and can replenish qi, harmonize the stomach and promote the production of body fluid, and relieve phlegm and cough. It is used for spleen deficiency, poor appetite, loose stools, weakness in the limbs, palpitations, shortness of breath, dry mouth, spontaneous sweating, prolapse of the anus, prolapse of the genitals, and replenishing vital energy.

[0023] Astragalus is the root of the leguminous plant Astragalus mongolica. It is dug in spring and autumn, and the soil, fibrous roots and root heads are removed. It is dried in the sun until 60% to 70% dry, straightened and tied into bundles before drying. It is sweet and slightly warm in nature. It enters the lung, spleen, liver and kidney meridians. It has the effects of enhancing the body's immune function, protecting the liver, diuresis, anti-aging, anti-stress, lowering blood pressure and a wide range of antibacterial effects, and can be used to increase immunity.

[0024] Angelica sinensis is the dried root of the Umbelliferae plant Angelica sinensis. It is dug up in late autumn, and the reed head and fibrous roots are removed. After the water evaporates slightly, it is bundled into small bundles according to size and thickness. It is slowly smoked dry with a low fire or smoked with sulfur. It can be cut into slices for moth and mildew prevention and used raw, or mixed with wine or fried with wine. It tastes sweet, slightly bitter, and slightly numbing. It tastes sweet and spicy and is warm in nature. It enters the liver, heart, and spleen meridians. It has the effects of nourishing blood and activating blood circulation, regulating menstruation and relieving pain, moistening the intestines and relieving constipation, anti-cancer, anti-aging and immunity. It is mainly used to treat blood deficiency and sallow complexion, dizziness and palpitations, irregular menstruation, amenorrhea and dysmenorrhea, abdominal pain due to deficiency and cold, rheumatic arthralgia, injuries from falls, carbuncles and ulcers, and constipation due to dry intestines. It can be used to activate blood circulation and remove blood stasis, and relieve constipation.

[0025] Rehmannia glutinosa is the rhizome of Rehmannia glutinosa or Rehmannia glutinosa of the Scrophulariaceae family, which is processed and steamed and dried. It is sweet and slightly warm in nature, and enters the liver and kidney meridians. It nourishes blood and yin, replenishes essence and fills marrow. It is mainly used to treat liver and kidney yin deficiency, soreness of waist and knees, hot flashes due to bone steaming, night sweats and spermatorrhea, internal heat and thirst, blood deficiency and sallow complexion, palpitations, irregular menstruation, metrorrhagia, dizziness and tinnitus, and premature graying of hair. It can be used to nourish blood.

[0026] Gleditsia sinensis is the dried thorn of the leguminous plant soapberry. It can be harvested and dried throughout the year, or sliced ​​and dried while fresh. The decoction piece is an irregular thick slice. The wood on the surface is yellow-white, the pith is spongy and light reddish brown, and the surrounding area is brown-purple or brown-brown. It is brittle and easy to break. It is odorless and has a light taste. It tastes spicy and is warm in nature. It enters the liver and stomach meridians. It has the effects of reducing swelling, expelling toxins, draining pus, and killing insects. It is often used for carbuncle at the beginning or pus that does not break; it is also used for external treatment of scabies, leprosy.

[0027] Chuanxiong is the dried rhizome of the plant Chuanxiong of the Umbelliferae family. It is dug in May, the sand is removed, and the root is dried after being exposed to the sun, and the fibrous roots are removed. When used, it is sliced ​​and used raw or roasted with wine. It is pungent in nature and warm in flavor. It enters the liver, gallbladder, and pericardium meridians. It has the effects of promoting qi and relieving depression, removing wind and dampness, and activating blood circulation and relieving pain. It is mainly used to treat headaches and dizziness caused by wind and cold, abdominal pain, cold arthralgia and muscle spasms, amenorrhea, dystocia, postpartum blood stasis and pain, carbuncle and ulcer. It is used for irregular menstruation, amenorrhea and dysmenorrhea, abdominal pain caused by masses, stabbing pain in the chest and ribs, swelling and pain caused by falls, headaches, and rheumatic pain.

[0028] Shengdi, also known as Shengdihuang, Yedihuang, and Shanyangen, is the root of Rehmannia glutinosa, a plant of the Scrophulariaceae family. It is sweet, bitter, and cold in nature; it enters the heart, liver, and kidney meridians. It has the effects of clearing heat and cooling blood, nourishing yin and promoting body fluid. It is mainly used to treat heat entering the blood, red tongue and thirst, macules and vomiting and bleeding, yin deficiency and internal heat, bone steaming and fatigue fever, thirst due to loss of body fluid, internal heat and thirst, and dry intestines and constipation.

[0029] White mustard is the tender stem and leaves of the white mustard plant of the cruciferous family. It is cultivated in many parts of the country. The seeds of white mustard are used as medicine, containing white sinigrin, myrosinase, sinapines, 4-hydroxybenzoylcholine, 4-hydroxybenzylamine and other ingredients. It is warm in nature, pungent in taste, and non-toxic. It enters the lungs. It has the functions of warming the lungs, relieving diseases and promoting qi, dispersing knots and dredging collaterals and relieving pain. It is used for cold-induced cough, chest and flank distension and pain, phlegm stagnation, numbness of meridians and joints, phlegm-dampness flow, and swelling and poison in the yin.

[0030] Achyranthes bidentata is a perennial herbaceous plant of the Amaranthaceae family. It is a commonly used bulk Chinese medicinal material and one of the famous "Four Huai Medicines". It is a specialty of Jiaozuo City, Henan Province. It has a bitter, sour and flat smell. It is mainly used to treat cold and dampness, paralysis, cramps in the limbs, knee pain that cannot be flexed and extended, expel blood and qi, and damage heat and fire. Long-term use can make the body light and resist aging. It is good at nourishing the liver and kidneys, strengthening the waist and knees, and promoting blood circulation and guiding blood downward. Achyranthes bidentata contains a large amount of alkaloids, which can nourish the liver and kidneys, strengthen the tendons and bones, dredge the meridians, and disperse bad blood. It is commonly used in the clinic to treat cold and dampness, pain in the waist and knees, soreness of the waist and knees, cramps in the limbs, irregular menstruation, abdominal pain due to blood stasis after childbirth, hematuria, traumatic injury, and knee flexion disorder. It is one of the commonly used drugs for dredging meridians and promoting blood circulation in traditional Chinese medicine prescriptions.

[0031] Qingpi is the dried young fruit or immature fruit peel of the citrus plant and its cultivated varieties of the Rutaceae family. It is produced in Fujian, Zhejiang, Guangdong, Guangxi, Jiangxi, Hunan, Guizhou, Yunnan, Sichuan and other places. Remove impurities, wash, steam, cut into thick slices or shreds, and dry in the sun. Collect the fallen young fruits from May to June, dry them in the sun, and are commonly known as "geqingpi"; harvest the immature fruits from July to August, cut them into four petals on the peel to the base, remove the pulp petals, and dry them in the sun, which is commonly known as "sihuaqingpi". It tastes bitter and spicy, and is warm in nature. It enters the liver, gallbladder, and stomach meridians. It has the effects of soothing the liver and breaking qi, eliminating accumulation and stagnation. It is used for chest and flank distension and pain, hernia pain, breast lumps, breast abscesses, food accumulation and qi stagnation, and abdominal distension and pain.

[0032] Tangerine peel is the dried mature peel of the citrus plant and its cultivated varieties in the Rutaceae family. Pick the mature fruits, peel the peel, and dry them in the sun or at low temperature. It tastes bitter and pungent, and is warm in nature. It enters the lung and spleen meridians. Its functions are to regulate qi and strengthen the spleen, and to dry dampness and resolve phlegm. It is mainly used to treat abdominal distension, loss of appetite, vomiting and diarrhea, and cough with excessive phlegm. It is used together with Atractylodes lancea and Magnolia officinalis, and is used for patients with cold dampness in the middle jiao, spleen and stomach qi stagnation, abdominal distension and pain, nausea, vomiting, and diarrhea.

[0033] Cistanche deserticola is the fleshy stem of the Orobanchaceae plant Cistanche deserticola or Cistanche deserticola, Cistanche deserticola, etc. It can be harvested in spring and autumn. However, it is better to harvest between March and May, as it is hollow after that. Those harvested in spring are usually half buried in sand and dried in the sun. The products are called sweet dayun, light dayun or light dayun. Those harvested in autumn are not easy to dry because of the high moisture content. They must be put into the salt lake for 1 to 3 years, then taken out and dried. They are called salt dayun, salty dayun or salty dayun. It is sweet and salty in nature and has a flat qi. It enters the kidney and large intestine meridians. It has the effects of tonifying the kidney, benefiting the essence, moisturizing dryness and lubricating the intestines. It is mainly used to treat male impotence, female infertility, leucorrhea, hemorrhage, cold pain in the waist and knees, and constipation due to blood deficiency.

[0034] Epimedium is the stem and leaf of the plants Epimedium, Epimedium cordifolium or Epimedium sagittatum of the Berberidaceae family. It is harvested in summer and autumn, the stems and leaves are cut, impurities are removed, and they are dried in the sun. It is pungent and sweet in nature and warm in nature. It enters the liver and kidney meridians. It is an important medicine for replenishing the gate of life, benefiting the essence and qi, strengthening the tendons and bones, and replenishing the kidney and strengthening yang. It is often used clinically to treat male impotence, premature ejaculation, incontinence and female infertility. It has the effects of replenishing the kidney and strengthening yang, dispelling wind and dampness. It is mainly used to treat impotence and premature ejaculation, back pain and leg pain, numbness of the limbs, hemiplegia, neurasthenia, forgetfulness, tinnitus, and dizziness.

[0035] Turtle shell is the plastron and carapace of the turtle, an aquatic reptile of the family Testudinidae. It is also called tortoise shell. The main producing areas are Zhejiang, Hubei, Hunan, etc. Turtle shell is best when it is dry, has blood spots on the plate, is large and has no rotten meat. It tastes salty and sweet, and is slightly cold in nature. It enters the liver, kidney and heart meridians. It has the effects of nourishing yin and suppressing yang, benefiting the kidney and strengthening bones, nourishing blood and replenishing the heart, and consolidating menstruation and stopping metrorrhagia. It is often used for yin deficiency, hot flashes, bone steaming and night sweats, dizziness, internal movement of virtual wind, weakness of tendons and bones, heart deficiency and forgetfulness, and frequent metrorrhagia.

[0036] The turtle shell is the carapace of the turtle of the family Testudinidae. It can be caught all year round, but mostly in autumn and winter. After being caught, it is killed and put into boiling water until the hard skin on the carapace can be peeled off, then taken out, the carapace peeled off, the remaining meat removed, and dried in the sun. It is distributed in places such as Taiwan. It tastes salty and is slightly cold in nature. It enters the liver and kidney meridians. It has the effects of nourishing yin and suppressing yang, reducing fever and removing steaming, softening and dispersing nodules. It is often used for fever due to yin deficiency, bone steaming and fatigue fever, yin deficiency and yang hyperactivity, dizziness, internal wind movement, amenorrhea, lumps, and long-term malaria.

[0037] Cyperus rotundus, also known as Cyperus rotundus, is the dried rhizome of Cyperus rotundus, a plant of the Cyperaceae family. It is pungent, slightly bitter, slightly sweet, and neutral in nature. It enters the liver, spleen, and triple burner meridians. It has the effects of soothing the liver and relieving depression, regulating qi and relieving fullness, regulating menstruation and relieving pain. It is used for liver depression and qi stagnation, chest and flank distension and pain, hernia pain, breast distension and pain, spleen and stomach qi stagnation, abdominal distension and pain, irregular menstruation, and amenorrhea and dysmenorrhea.

[0038] Preferably, the raw materials of the composition include, by weight: 8-12 parts of deer placenta glue, 14-16 parts of Atractylodes macrocephala, 12-15 parts of Codonopsis pilosula, 15-25 parts of Astragalus, 12-18 parts of Angelica sinensis, 10-13 parts of Rehmannia glutinosa, 9-15 parts of Gleditsia sinensis thorns, 10-12 parts of Ligusticum chuanxiong, 14-16 parts of Rehmannia glutinosa, 12-15 parts of Sinapis alba, 10-12 parts of Achyranthes bidentata, 8-10 parts of Citrus reticulata, 8-10 parts of Cistanche deserticola, 12-32 parts of Epimedium, 12-15 parts of Tortoise shell, 15-25 parts of Carapax tricolor, and 12-15 parts of Cyperus rotundus.

[0039] More preferably, the raw materials comprise by weight: 9g of deer placenta glue, 15g of Atractylodes macrocephala, 12g of Codonopsis pilosula, 20g of Astragalus, 12g of Angelica sinensis, 10g of Rehmannia glutinosa, 9g of Gleditsia sinensis, 12g of Ligusticum chuanxiong, 15g of Rehmannia glutinosa, 12g of Sinapis alba, 10g of Cyperus rotundus, 9g of Citrus aurantium, 9g of Citrus reticulata, 12g of Cistanche deserticola, 12g of Epimedium, 15g of Tortoise shell, 15g of Turtle shell, and 12g of Cyperus rotundus.

[0040] All raw materials are wild Chinese herbal medicines, and perennial ones are five years or more old. If the materials are taken from wild rare animals and plants, if conditions do not allow, materials taken from artificial breeding and planting, or other substitutes with the same or similar effects can be used.

[0041] The present invention also provides the use of the Tongluo prescription composition for infertility, and the composition is used for preparing an oral medicament.

[0042] The invention also provides a preparation method of the medicine, which comprises the following steps: weighing various drug raw materials in proportion, washing and drying washable raw materials, grinding and crushing all raw materials, boiling with water, filtering to obtain liquid medicine, and dividing for use.

[0043] Preferably, when boiling with water, first boil at 80°C for 35 minutes over a low heat, then boil at 120°C for 40 minutes over a high heat, filter and divide the resulting medicinal solution into small packets, each packet of 180g, and seal and store for later use.

[0044] In the method, a medicine decoction machine is used to decoct the Chinese medicine, and a 10-day supply of the Chinese medicine is decocted at one time.

[0045] The liquid medicine obtained by the method is taken twice a day, one pack each in the morning and afternoon, and the temperature of the liquid medicine is controlled at 40°C during oral administration.

[0046] The equipment and specific conditions and parameters used in the method of the present invention are all known to those skilled in the art.

[0047] The Tongluo prescription composition for infertility provided by the present invention, its use and preparation method are further described below in conjunction with the embodiments.

[0048] Example 1

[0049] A Tongluo prescription composition for infertility, the raw materials of the composition comprising, by weight:

[0050] 8 parts of deer placenta glue, 14 parts of Atractylodes macrocephala, 12 parts of Codonopsis pilosula, 15 parts of Astragalus, 12 parts of Angelica sinensis, 10 parts of Rehmannia glutinosa, 9 parts of Spina Gleditsiae, 10 parts of Ligusticum chuanxiong, 14 parts of Rehmannia glutinosa, 12 parts of Sinapis alba, 10 parts of Cyathula officinalis, 8 parts of Pericarpium Citri Reticulatae, 8 parts of Pericarpium Citri Reticulatae, 12 parts of Cistanche deserticola, 12 parts of Epimedium, 15 parts of Plastrum Testudinis, 15 parts of Carapax Trionycis, and 12 parts of Rhizoma Cyperi.

[0051] This embodiment also provides the use of the Tongluo prescription composition for infertility, and the composition is used to prepare a medicament for oral administration.

[0052] This embodiment also provides a method for preparing the medicament, which is:

[0053] Weigh each medicinal raw material in proportion, wash and dry the washable raw materials, then grind all the raw materials, add water and boil them, filter to obtain the medicinal liquid, and divide it for use.

[0054] Preferably, the method uses a Beijing Donghuayuan brand fully automatic computerized decoction machine to decoct 10 days' worth of Chinese medicine at a time. When adding water for decoction, first use a slow fire at 80°C for 35 minutes, then use a high fire at 120°C for 40 minutes, filter and divide the resulting medicinal liquid into small packages, each package is 180g, and seal and store for later use.

[0055] The obtained liquid medicine is taken twice a day, one pack each in the morning and afternoon, and the temperature of the liquid medicine is controlled at 40°C during oral administration.

[0056] Example 2

[0057] A Tongluo prescription composition for infertility, the raw materials of the composition comprising, by weight:

[0058] 12 parts of deer placenta glue, 16 parts of Atractylodes macrocephala, 15 parts of Codonopsis pilosula, 25 parts of Astragalus, 18 parts of Angelica sinensis, 13 parts of Rehmannia glutinosa, 15 parts of Spina Gleditsiae, 12 parts of Ligusticum chuanxiong, 16 parts of Rehmannia glutinosa, 15 parts of Sinapis alba, 12 parts of Cyathula officinalis, 10 parts of Pericarpium Citri Reticulatae, 10 parts of Pericarpium Citri Reticulatae, 32 parts of Cistanche deserticola, 15 parts of Epimedium, 25 parts of Plastrum Testudinis, 25 parts of Carapax Trionycis, and 15 parts of Rhizoma Cyperi.

[0059] This embodiment also provides the use of the Tongluo prescription composition for infertility, and the composition is used to prepare a medicament for oral administration.

[0060] This embodiment also provides a method for preparing the medicament, which is:

[0061] Weigh each medicinal raw material in proportion, wash and dry the washable raw materials, then grind all the raw materials, add water and boil them, filter to obtain the medicinal liquid, and divide it for use.

[0062] Preferably, the method uses a Beijing Donghuayuan brand fully automatic computerized decoction machine to decoct 10 days' worth of Chinese medicine at a time. When adding water for decoction, first use a slow fire at 80°C for 35 minutes, then use a high fire at 120°C for 40 minutes, filter and divide the resulting medicinal liquid into small packages, each package is 180g, and seal and store for later use.

[0063] The obtained liquid medicine is taken twice a day, one pack each in the morning and afternoon, and the temperature of the liquid medicine is controlled at 40°C during oral administration.

[0064] Example 3

[0065] A Tongluo prescription composition for infertility, the raw materials of the composition comprising, by weight:

[0066] 10 parts of deer placenta glue, 15 parts of Atractylodes macrocephala, 14 parts of Codonopsis pilosula, 22 parts of Astragalus, 16 parts of Angelica sinensis, 12 parts of Rehmannia glutinosa, 10 parts of Spina Gleditsiae, 11 parts of Ligusticum chuanxiong, 15 parts of Rehmannia glutinosa, 14 parts of Sinapis alba, 11 parts of Cyathula officinalis, 9 parts of Pericarpium Citri Reticulatae, 9 parts of Pericarpium Citri Reticulatae, 22 parts of Cistanche deserticola, 14 parts of Epimedium, 20 parts of Plastrum Testudinis, 20 parts of Carapax Trionycis, and 14 parts of Rhizoma Cyperi.

[0067] This embodiment also provides the use of the Tongluo prescription composition for infertility, and the composition is used to prepare a medicament for oral administration.

[0068] This embodiment also provides a method for preparing the medicament, which is:

[0069] Weigh each medicinal raw material in proportion, wash and dry the washable raw materials, then grind all the raw materials, add water and boil them, filter to obtain the medicinal liquid, and divide it for use.

[0070] Preferably, the method uses a Beijing Donghuayuan brand fully automatic computerized decoction machine to decoct 10 days' worth of Chinese medicine at a time. When adding water for decoction, first use a slow fire at 80°C for 35 minutes, then use a high fire at 120°C for 40 minutes, filter and divide the resulting medicinal liquid into small packages, each package is 180g, and seal and store for later use.

[0071] The obtained liquid medicine is taken twice a day, one pack each in the morning and afternoon, and the temperature of the liquid medicine is controlled at 40°C during oral administration.

[0072] Example 4

[0073] A Tongluo prescription composition for infertility, the raw materials of the composition comprising by weight:

[0074] Deer placenta glue 9g, Atractylodes macrocephala 15g, Codonopsis pilosula 12g, Astragalus membranaceus 20g, Angelica sinensis 12g, Rehmannia glutinosa 10g, Gleditsia sinensis thorn 9g, Ligusticum chuanxiong 12g, Rehmannia glutinosa 15g, Sinapis alba 12g, Achyranthes bidentata 10g, Citrus aurantium 9g, Tangerine peel 9g, Cistanche deserticola 12g, Epimedium 12g, Tortoise shell 15g, Turtle shell 15g, Cyperus rotundus 12g.

[0075] This embodiment also provides the use of the Tongluo prescription composition for infertility, and the composition is used to prepare an oral medicament.

[0076] This embodiment also provides a method for preparing the medicament, which is:

[0077] Weigh each medicinal raw material in proportion, wash and dry the washable raw materials, then grind all the raw materials, add water and boil them, filter to obtain the medicinal liquid, and divide it for use.

[0078] Preferably, the method uses a Beijing Donghuayuan brand fully automatic computerized decoction machine to decoct 10 days' worth of Chinese medicine at a time. When adding water for decoction, first use a slow fire at 80°C for 35 minutes, then use a high fire at 120°C for 40 minutes, filter and divide the resulting medicinal liquid into small packages, each package is 180g, and seal and store for later use.

[0079] The obtained liquid medicine is taken twice a day, one pack each in the morning and afternoon, and the temperature of the liquid medicine is controlled at 40°C during oral administration.

[0080] The raw materials used in the embodiments of the present invention respectively comply with the corresponding national standards and regulations.

[0081] The medicament prepared by the present invention was used for clinical trials, and the ingredients could be added or subtracted according to the specific situation. The results showed that the composition had obvious efficacy, and typical cases were collected as follows.

[0082] Case 1: Chen, female, 29 years old, from Nankang, Ganzhou City.

[0083] Infertility after 3 years of marriage. The patient had her first menstruation at the age of 15. Usually, her menstruation was delayed for 30 to 50 days, but it was also irregular. The menstrual color was dark, the menstrual volume was small, there was dysmenorrhea, and it was clean every 5 days. She had been examined and treated in many hospitals. The examination showed that both ovaries had more than 12 follicles. The examination showed adenomyosis and thin endometrium. She had been treated with Chinese and Western medicine in Ganzhou Maternal and Child Health Hospital and Nanchang Maternal and Child Health Hospital, but it was ineffective. The patient weighed 129 pounds, often had sore waist and knees, cold limbs, pale tongue, thick white fur, and slippery and thin pulse.

[0084] The syndrome is spleen and kidney deficiency, spleen deficiency. It is intended to nourish the kidney and blood, resolve phlegm and dredge the meridians.

[0085] Prescription, modified prescription for polycystic disease: 15g of Astragalus, 15g of Gleditsia sinensis, 15g of Poria, 15g of Rehmannia glutinosa, 12g of Ligusticum chuanxiong, 13g of Cinnamon bark, 16g of Dendrobium officinale, 15g of Morinda officinalis, 15g of White Sinapis, 12g of Cyperus rotundus, 15g of Ophiopogon japonicus, 9g of Citrus aurantium, 9g of Tangerine peel, 13g of Cistanche deserticola, 12g of Deer Placenta Paste (Deer Placenta Glue).

[0086] Ten doses at a time. Usage: decoction, one dose per day, divided into two doses.

[0087] Take the above prescription with or without any other ingredients for three months and you will conceive naturally.

[0088] Case 2: Lin Moumou, female, 32 years old, from Nankang, Ganzhou City.

[0089] Infertility after 4 years of marriage. The patient had her first menstruation at the age of 13. Her menstruation was usually delayed for 50 to 80 days, but it was also irregular. The menstrual color was dark, the menstrual volume was small, there was dysmenorrhea, and it was clean every 8 days. She had been examined and treated in many hospitals. The examination showed that both ovaries had more than 12 follicles. The treatment of Chinese and Western medicine in major hospitals was ineffective. The patient weighed 155 pounds, often had sore waist and knees, cold limbs, loose stools, pale tongue, thin white fur, and thin pulse.

[0090] The syndrome is spleen and kidney deficiency, liver stasis. It is intended to nourish the kidney and blood, resolve phlegm and dredge the meridians.

[0091] Prescription, modified prescription for polycystic disease: 15g of Astragalus, 15g of Gleditsia sinensis, 15g of Poria, 15g of Rehmannia glutinosa, 12g of Ligusticum chuanxiong, 16g of Dendrobium officinale, 15g of Morinda officinalis, 15g of White Sinapis, 12g of Cyperus rotundus, 15g of Ophiopogon japonicus, 9g of Citrus aurantium, 9g of Tangerine peel, 13g of Cistanche deserticola, and 12g of Deer Placenta Paste.

[0092] Ten doses at a time. Usage: decoction, one dose per day, divided into two doses.

[0093] Take the above prescription with or without any other ingredients for three months and you will conceive naturally.

[0094] Case 3: Tian Moumou, female, 36 years old, from Xinning Town, Wuning County.

[0095] Infertility after 9 years of marriage. The patient had her first menstruation at the age of 14. Usually, her menstruation comes once every 2 months. The menstrual color is dark, there are blood clots, the menstrual flow is very small, there is mild dysmenorrhea, and it lasts for 7 days. She was examined and treated at Nanchang Women's Health Hospital. The examination at Wuning County Women's Health Hospital showed that both ovaries had 12 small follicles. Western medicine treatment for several years was ineffective. The patient weighed 160 pounds, often had sore waist and knees, cold limbs, loose stools, pale tongue, thin white fur, and thin pulse.

[0096] The syndrome is spleen and kidney deficiency, spleen deficiency. It is intended to tonify the kidney and spleen, resolve phlegm and dredge the meridians.

[0097] Prescription, modified version of the polycystic prescription: 25g of Astragalus, 15g of Gleditsia sinensis, 15g of Poria, 15g of Rehmannia glutinosa, 12g of Ligusticum chuanxiong, 16g of Dendrobium officinale, 15g of Atractylodes macrocephala, 15g of Codonopsis pilosula, 12g of Bupleurum chinense, 15g of White Sinapis, 12g of Cyperus rotundus, 15g of Ophiopogon japonicus, 9g of Citrus aurantium, 9g of Atractylodes macrocephala, 15g of Coix seed, 9g of Citrus reticulata, 13g of Cistanche deserticola, 15g of Epimedium, and 12g of Deer Placenta Paste.

[0098] Ten doses at a time. Usage: decoction, one dose per day, divided into two doses.

[0099] Take the above prescription with or without modifications for 5 months and you will conceive naturally.

[0100] Case 4: Han Moumou, female, 32 years old, from Yining Town, Xiushui County.

[0101] Infertility after 6 years of marriage. The patient had her first menstruation at the age of 15. Usually, her menstruation comes once every 2 months. The menstrual color is dark, the menstrual flow is very small, and there is slight dysmenorrhea. It lasts for 8 days. She has been examined and treated in Nanchang Women's and Children's Hospital and Xiushui Women's and Children's Hospital. The examination showed that both ovaries have 12 small follicles. She has been treated with Chinese and Western medicine in major hospitals for several years, but it is ineffective. The patient weighs 145 catties, often has sore waist and knees, cold limbs, loose stools, pale tongue, thin white fur, and thin pulse.

[0102] The syndrome is spleen and kidney deficiency, spleen deficiency. It is intended to tonify the kidney and spleen, resolve phlegm and dredge the meridians.

[0103] Prescription, modified version of the polycystic prescription: 25g of Astragalus, 15g of Gleditsia sinensis, 15g of Poria, 15g of Rehmannia glutinosa, 12g of Ligusticum chuanxiong, 16g of Dendrobium officinale, 25g of Rhizoma Smilacis Glabrae, 15g of White Sinapis, 12g of Cyperus rotundus, 15g of Ophiopogon japonicus, 9g of Citrus aurantium, 9g of Atractylodes macrocephala, 15g of Coix seed, 9g of Citrus reticulata, 13g of Cistanche deserticola, 15g of Epimedium, and 12g of Deer Placenta Paste.

[0104] Ten doses at a time. Usage: decoction, one dose per day, divided into two doses.

[0105] Take the above prescription with or without any other ingredients for 3 consecutive months and you will conceive naturally.

[0106] Case 5: Lv Moumou, female, 42 years old, from Daxing District, Beijing.

[0107] Infertility after 8 years of marriage. The patient had her first menstruation at the age of 14. Usually, her menstruation comes every 2 to 3 months. The menstrual color is dark, there are blood clots, the menstrual flow is very small, and there is severe dysmenorrhea. It lasts for 8 days. She was examined and treated at Nanchang Women's and Children's Hospital. The examination showed that both ovaries had 13 small follicles. She was treated with Chinese and Western medicine in major hospitals for several years and had two test tubes, but it was ineffective. The patient weighed 155 pounds, often had sore waist and knees, cold limbs, loose stools, pale tongue, thin white fur, and thin pulse.

[0108] The syndrome is spleen and kidney deficiency, spleen deficiency. It is intended to tonify the kidney and spleen, resolve phlegm and dredge the meridians.

[0109] Prescription, modified version of the polycystic prescription: 25g of Astragalus, 15g of Gleditsia sinensis, 15g of Poria, 15g of Rehmannia glutinosa, 12g of Ligusticum chuanxiong, 16g of Dendrobium officinale, 15g of Atractylodes macrocephala, 15g of Codonopsis pilosula, 12g of Bupleurum chinense, 15g of White Sinapis, 12g of Cyperus rotundus, 15g of Ophiopogon japonicus, 9g of Citrus aurantium, 9g of Atractylodes macrocephala, 15g of Coix seed, 9g of Citrus reticulata, 13g of Cistanche deserticola, 15g of Epimedium, and 12g of Deer Placenta Paste.

[0110] Ten doses at a time. Usage: decoction, one dose per day, divided into two doses.

[0111] Take the above prescription with or without modifications for 5 months and you will conceive naturally.

[0112] Case 6: Rao Mou, female, 26 years old, from Sandu Town, Xiushui County.

[0113] Infertility after 3 years of marriage. The patient had her first menstruation at the age of 14. Her menstruation usually comes every 2 to 5 months. The menstrual color is dark, there are blood clots, the menstrual flow is very small, there is severe dysmenorrhea, and it lasts for 7 days. She was examined and treated at Nanchang Women's Health Hospital. The examination at Xiushui County Women's Health Hospital showed that both ovaries had 12 small follicles. Western medicine treatment for several years was ineffective. The patient weighed 160 pounds, often had sore waist and knees, cold limbs, loose stools, pale tongue, thin white fur, and thin pulse.

[0114] The syndrome is spleen and kidney deficiency, spleen deficiency. It is intended to tonify the kidney and spleen, resolve phlegm and dredge the meridians.

[0115] Prescription, modified version of the polycystic prescription: 25g of Astragalus, 15g of Gleditsia sinensis, 15g of Poria, 15g of Rehmannia glutinosa, 12g of Ligusticum chuanxiong, 16g of Dendrobium officinale, 15g of Atractylodes macrocephala, 15g of Codonopsis pilosula, 12g of Bupleurum chinense, 15g of White Sinapis, 12g of Cyperus rotundus, 15g of Ophiopogon japonicus, 9g of Citrus aurantium, 9g of Atractylodes macrocephala, 15g of Coix seed, 9g of Citrus reticulata, 13g of Cistanche deserticola, 15g of Epimedium, and 12g of Deer Placenta Paste.

[0116] Ten doses at a time. Usage: decoction, one dose per day, divided into two doses.

[0117] Take the above prescription with or without modifications for 5 months and you will conceive naturally.

[0118] Case 7: Li, female, 32 years old, from Wuning County Agricultural Science Institute.

[0119] Infertility for 6 years after marriage, the patient had menarche at the age of 15, normal menstrual cycle before the age of 20, and rare menstruation after the age of 20, often once every 2-3 months, at most once every 5 months, dark color, small amount, dark color, accompanied by more blood clots, dysmenorrhea, and was diagnosed as "polycystic ovary" in many hospitals and given intermittent treatment with Chinese and Western medicine, but the effect was not obvious. The basal body temperature is monophasic, the body is fat, weighing 145 pounds, sometimes with back pain and weak knees, pale and dark tongue, thin white fur, and tooth marks, and thin pulse.

[0120] The syndrome is kidney deficiency and blood stasis, and the treatment is to tonify the kidney and nourish blood, resolve phlegm and dredge the meridians.

[0121] Prescription, modified prescription for polycystic ovary syndrome: 25g of Astragalus, 15g of Angelica sinensis, 15g of Gleditsia sinensis thorn, 12g of Ligusticum chuanxiong, 15g of Rehmannia glutinosa, 12g of White Sinapis seed, 10g of Achyranthes bidentata, 9g of Citrus aurantium, 9g of Tangerine peel, 30g of Cistanche deserticola, 15g of Epimedium, 25g of Tortoise shell, and 25g of Turtle shell.

[0122] Ten doses at a time. Usage: decoction, one dose per day, divided into two doses.

[0123] The patient became pregnant naturally after taking the medicine for three months with adjustments based on symptoms.

[0124] Case 8: Zheng Moumou, female, 28 years old, from Xialiu Village, Xinning Town, Wuning County.

[0125] Infertility after six years of marriage. The patient had her first menstruation at the age of 16. Her menstruation was usually delayed by 50 to 80 days, with no regularity, dark menstrual color, small menstrual volume, dysmenorrhea, and 8 days of cleanliness. She had been examined and treated in many hospitals. The examination showed that both ovaries had 12 follicles. Treatment with Chinese and Western medicine in major hospitals was ineffective. The patient weighed 135 pounds, often had sore waist and knees, cold limbs, loose stools, frequent urination at night, pale tongue, thin white fur, and thin pulse.

[0126] The syndrome is spleen and kidney deficiency, liver stasis. It is intended to nourish the kidney and blood, resolve phlegm and dredge the meridians.

[0127] Prescription, modified prescription for polycystic ovary syndrome: 25g of Astragalus, 15g of Gleditsia sinensis, 15g of Poria, 15g of Rehmannia glutinosa, 12g of Ligusticum chuanxiong, 16g of Dendrobium officinale, 25g of Rhizoma Smilacis Glabrae, 15g of White Sinapis, 12g of Cyperus rotundus, 15g of Ophiopogon japonicus, 9g of Citrus aurantium, 9g of Citrus reticulata, 13g of Cistanche deserticola, 15g of Epimedium, and 12g of Deer Placenta Paste.

[0128] Ten doses at a time. Usage: decoction, one dose per day, divided into two doses.

[0129] Take the above prescription with or without any other ingredients for three months and you will conceive naturally.

[0130] Case 9: Yang Moumou, female, 28 years old, from Huizhou City, Guangdong Province.

[0131] Infertility after 9 years of marriage. The patient had her first menstruation at the age of 13. Usually, her menstruation comes once every 2 months. The menstrual color is dark, the menstrual flow is very small, and there is severe dysmenorrhea. It lasts for 6 days. She was examined and treated at Shenzhen Women's and Children's Hospital. The examination showed that both ovaries had 10 small follicles. She was treated with Chinese and Western medicine in major hospitals for several years and had three IVFs, but it was ineffective. The patient weighed 125 catties, often had sore waist and knees, cold limbs, loose stools, pale tongue, thin white fur, and thin pulse.

[0132] The syndrome is spleen and kidney deficiency, spleen deficiency. It is intended to tonify the kidney and spleen, resolve phlegm and dredge the meridians.

[0133] Prescription, modified version of the polycystic prescription: 25g of Astragalus, 15g of Gleditsia sinensis, 15g of Poria, 15g of Rehmannia glutinosa, 12g of Ligusticum chuanxiong, 16g of Dendrobium officinale, 25g of Rhizoma Smilacis Glabrae, 15g of White Sinapis, 12g of Cyperus rotundus, 15g of Ophiopogon japonicus, 9g of Citrus aurantium, 9g of Atractylodes macrocephala, 15g of Coix seed, 9g of Citrus reticulata, 13g of Cistanche deserticola, 15g of Epimedium, and 12g of Deer Placenta Paste.

[0134] Ten doses at a time. Usage: decoction, one dose per day, divided into two doses.

[0135] Take the above prescription with modifications for 7 consecutive months and you will conceive naturally.

[0136] Case 10: Wang, female, 29 years old, lives in Honggutan, Nanchang.

[0137] Infertility for 5 years after marriage, the patient had her first menstruation at the age of 14, and delayed menstruation 6 years ago without obvious inducement, often once every 2-3 months, the longest once every 5 months, dark color, small amount, accompanied by more blood clots, severe dysmenorrhea, diagnosed as "polycystic ovary" in other hospitals and given intermittent treatment with Chinese medicine, but the effect was not obvious, and now the menstruation is blocked for two months. The basal body temperature is monophasic, the body is fat, weighing 150 pounds, with occasional back pain, pale and dark tongue, thin white fur, and tooth marks, and thin pulse.

[0138] The syndrome is kidney deficiency and blood stasis. It is intended to nourish the kidney and blood, resolve phlegm and dredge the meridians.

[0139] Prescription, modified prescription for polycystic ovary syndrome: 20g of Astragalus, 18g of Angelica sinensis, 10g of Gleditsia sinensis spine, 12g of Ligusticum chuanxiong, 15g of Rehmannia glutinosa, 12g of White Sinapis, 10g of Achyranthes bidentata, 9g of Citrus aurantium, 9g of Tangerine peel, 30g of Cistanche deserticola, 15g of Epimedium, 25g of Tortoise shell, 25g of Turtle shell, and 15g of Cyperus rotundus.

[0140] Efficacy: nourishes the kidney and blood, resolves phlegm and dredges the meridians. Ten doses each time.

[0141] Usage: Decoction in water, one dose per day, divided into two doses.

[0142] Add or subtract the above ingredients according to your symptoms, take them for 6 months and you will get pregnant naturally.

[0143] The invention provides a Tongluo prescription composition for infertility, and its use and preparation method. The obtained composition is a prescription for nourishing the kidney, nourishing blood, resolving phlegm and unblocking the meridians. It adopts natural Chinese herbal medicine raw materials, has basically no side effects, cures the symptoms and the root causes, has remarkable effects, and is worthy of extensive clinical application and promotion. The main effects of the prescription are nourishing the kidney, nourishing blood, resolving phlegm and unblocking the meridians. The prescription is explained as follows: in the whole prescription, Astragalus and Angelicae Sinensis invigorate qi and promote blood circulation; Atractylodes macrocephala and Codonopsis pilosula invigorate the spleen and invigorate qi, dry dampness and promote diuresis; Deer placenta glue warms the liver and kidney, invigorates essence and nourishes blood; Gleditsia sinensis warms and promotes pungent and dispersing, activates blood circulation and penetrates; Radix Rehmanniae nourishes blood and nourishes yin, invigorates the kidney and replenishes essence; Radix Achyranthis Bidentatae descends to invigorate the kidney and replenish essence; Epimedium and Cistanche deserticola invigorate the kidney, assist yang and benefit essence; Pericarpium Citri Reticulatae and Pericarpium Citri Reticulatae regulate qi and resolve phlegm; Cyperus rotundus soothes the liver and regulates the middle; White mustard removes phlegm and promotes qi, removes dampness and warms the middle; Tortoise shell and whole nail nourish the liver and kidney.

[0144] The present invention is based on the essence of Chinese medicine diagnosis, on the basis of four examinations and treatment based on syndrome differentiation, combined with the usual clinical summary, and the conclusion is: for the treatment of polycystic ovarian infertility, qi tonifying is indispensable. Qi tonifying medicine can promote the growth and development of follicles and can help the egg break through the ovary during ovulation and successfully fertilize. In addition, when qi moves, blood moves, and qi tonifying products can promote the movement of blood in the blood vessels so that it is no longer stagnant. Qi tonifying can also help the spleen to transport and transform, and spleen deficiency will lead to dampness, and spleen strength will lead to dampness. Therefore, for this disease, the diagnosis and treatment scheme can adopt a method combining unblocking and regulating, and regulating can nourish the kidney and replenish essence, and unblocking can eliminate phlegm and resolve phlegm. Through four examinations and reference, polycystic prescriptions are used for addition and subtraction treatment.

[0145] The Tongluo prescription composition obtained by the present invention is very exquisite in drug use, and many compatibilities are obtained through years of experience accumulation. Through TCM syndrome differentiation, targeting the etiology and pathogenesis of the disease, using the drug compatibility principle of mutual complementation, various drugs are purposefully and reasonably matched according to the organizational structure of monarch, minister, assistant and envoy, so that the drugs in the prescription and their compatibility are closely related to the pathogenesis of the disease, so that the comprehensive effect after drug compatibility is highly unified with the established treatment method.

[0146] Although the content of the present invention has been described in detail through the above preferred embodiments, it should be appreciated that the above description should not be considered as a limitation of the present invention. After reading the above content, it will be apparent to those skilled in the art that various modifications and substitutions of the present invention will occur. Therefore, the protection scope of the present invention should be limited by the appended claims.

Claims

1. A Tongluo prescription composition for infertility, characterized in that: The raw materials of the composition include: deer placenta glue, atractylodes macrocephala, codonopsis pilosula, astragalus, angelica, prepared rehmannia root, thorn of gleditsia sinensis, ligusticum chuanxiong, raw rehmannia root, white mustard seeds, cyathula officinalis, green peel, tangerine peel, cistanche deserticola, epimedium, tortoise shell, turtle shell and cyperus rotundus.

2. The Tongluo prescription composition for infertility according to claim 1, characterized in that: The raw materials of the composition include, by weight: 8-12 parts of deer placenta glue, 14-16 parts of Atractylodes macrocephala, 12-15 parts of Codonopsis pilosula, 15-25 parts of Astragalus, 12-18 parts of Angelica sinensis, 10-13 parts of Rehmannia glutinosa, 9-15 parts of Gleditsia sinensis thorns, 10-12 parts of Ligusticum chuanxiong, 14-16 parts of Rehmannia glutinosa, 12-15 parts of Sinapis alba, 10-12 parts of Cyperus rotundus, 8-10 parts of Citrus aurantium, 8-10 parts of Citrus reticulata, 12-32 parts of Cistanche deserticola, 12-15 parts of Epimedium, 15-25 parts of Tortoise shell, 15-25 parts of Turtle shell, and 12-15 parts of Cyperus rotundus.

3. The Tongluo prescription composition for infertility according to claim 2, characterized in that: The raw materials include, by weight: 9g of deer placenta glue, 15g of Atractylodes macrocephala, 12g of Codonopsis pilosula, 20g of Astragalus, 12g of Angelica sinensis, 10g of Rehmannia glutinosa, 9g of Gleditsia sinensis, 12g of Ligusticum chuanxiong, 15g of Rehmannia glutinosa, 12g of Sinapis alba, 10g of Cyperus rotundus, 9g of Citrus aurantium, 9g of Citrus reticulata, 12g of Cistanche deserticola, 12g of Epimedium, 15g of Tortoise shell, 15g of Turtle shell, and 12g of Cyperus rotundus.

4. A use of the Tongluo prescription composition for infertility as claimed in any one of claims 1 to 3, characterized in that: The composition is used for preparing an oral medicament.

5. A method for preparing the medicament according to claim 4, characterized in that: The method is as follows: weigh each drug raw material in proportion, wash and dry the washable raw materials, grind and crush all the raw materials, add water to boil, filter to obtain the medicinal solution, and divide it for use.

6. The method for preparing the medicament according to claim 5, characterized in that: In the method described, when adding water for decoction, first use a low heat at 80°C for 35 minutes, and then use a high heat at 120°C for 40 minutes. After filtering, the resulting medicinal liquid is divided into small packets, each packet is 180g, and sealed and stored for later use.

7. The method for preparing the medicament according to claim 6, characterized in that: In the method, a medicine decocting machine is used to decoct the Chinese medicine, and a 10-day amount of Chinese medicine is decocted at one time.

8. The method for preparing the medicament according to claim 7, characterized in that: The liquid medicine is taken twice a day, one pack each in the morning and afternoon, and the temperature of the liquid medicine is controlled at 40° C. during oral administration.