Movable plasma hematopoietic stem cell transplantation cabin

Abstract

A mobile plasma hematopoietic stem cell transplantation cabin comprises an integral frame formed by a plurality of groups of mounting support legs and mounting frame plates, and a plasma air sterilizer host is arranged in the transplantation cabin to provide clean air. The periphery of the cabin body is sealed through a PEVA transparent soft curtain (sealing soft curtain) capable of being unfolded and turned over, the soft curtain is controlled to be unfolded and stored through a soft curtain storage roller, and tight sealing is achieved through a sealing conveying belt and an attaching sealing plate. In addition, the transplanting cabin is further provided with a transmission mechanism for driving the soft curtain and the hanging mechanism to move synchronously and assisting the sealing mechanism to enhance the sealing effect. The transplantation cabin is designed to provide hematopoietic stem cell transplantation equipment which is convenient to move, mount and dismount and can effectively keep an internal sterile environment, so that the problem of shortage of medical land resources is solved, and meanwhile, the medical working efficiency and the treatment safety of patients are improved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical equipment, and in particular to a mobile device for hematopoietic stem cell transplantation that is capable of high-efficiency air purification and sealing functions, and specifically is a mobile plasma hematopoietic stem cell transplantation cabin. Background Art

[0002] The laminar flow ward is a ward that is kept sterile by air purification equipment and is equipped with equipment to change the cleanliness of the air environment. In order to keep the room sterile, the environment and air are disinfected daily, and items entering the laminar flow room must be sterile. There are also corresponding regulations for entering the room. When patients undergo hematopoietic stem cell transplantation, before the reconstruction of hematopoiesis and immune function, due to high-dose chemotherapy and radiotherapy, the patient's hematopoietic function and immune defense system are almost destroyed. The patient is in a state of severe immune deficiency with pancytopenia, and the patient is in bone marrow failure, which is very prone to various infections and other complications. Various pathogenic infections are the most common complications in hematopoietic stem cell transplantation and one of the main causes of death in hematopoietic stem cell transplantation. According to this particularity, the patient is protected and isolated in the entire environment, that is, it needs to be carried out in a special hematopoietic stem cell transplantation ward, also known as a sterile air laminar flow ward.

[0003] At present, the existing laminar flow wards are mainly installed on the ground. Not only do these wards occupy a large indoor floor space, but also their construction costs are high. In addition to requiring a large amount of capital investment for the purchase of professional equipment and fine decoration of the wards, the post-maintenance of laminar flow wards is also extremely complicated, requiring professionals to regularly maintain key equipment such as air purification systems, which undoubtedly further increases medical costs. In addition, due to the limited resources of the hospital, the area that can be provided for the placement of laminar flow wards is also quite limited, and generally only a small number of laminar flow wards can be supplied.

[0004] What is more serious is that the fixed location and large floor space of laminar flow wards greatly restrict the flexible layout and adjustment of hospital departments. When hospitals need to add more laminar flow wards to meet the growing demand, they have to plan to occupy other medical areas, which not only leads to the shortage of hospital land resources, but also seriously affects the optimal allocation and overall layout of hospital resources.

[0005] The severity of the problem goes far beyond this. According to relevant statistics, in some large hospitals, due to the severe shortage of laminar flow wards, many patients who need critical treatments such as hematopoietic stem cell transplantation have to face a long wait. The average waiting time is even as long as several months, which is undoubtedly a huge challenge for patients. During the waiting period, due to the inability to receive transplant surgery in time, the risk of infection of patients continues to increase and their physical condition deteriorates. According to statistics, about 50% of patients worsen their condition during the waiting process, which not only seriously affects the treatment effect of patients, but also greatly reduces their quality of life.

[0006] In summary, the many shortcomings of existing laminar flow wards not only increase medical costs and limit the optimal allocation of hospital resources, but also seriously affect the treatment effects and quality of life of patients, and urgently need improvement and innovation.

[0007] To this end, we propose a mobile plasma hematopoietic stem cell transplantation chamber Summary of the invention

[0008] The purpose of the present invention is to provide a mobile plasma hematopoietic stem cell transplantation chamber to solve the above-mentioned deficiencies in the prior art.

[0009] In order to achieve the above-mentioned purpose, the present invention provides the following technical solutions: including multiple groups of mounting support legs and multiple groups of mounting frame plates fixedly arranged on the mounting support legs, the multiple mounting frame plates form a rectangular frame when viewed from above, and the multiple groups of mounting support legs and the multiple groups of mounting frame plates are integrally formed into an overall frame of the transplant cabin, a plasma air disinfection machine main body for replacing air in the internal space of the overall frame is also arranged on the multiple mounting frame plates, a laminar clean hood with an air inlet is arranged on the closed frame plate, and the air replacement port of the plasma air disinfection machine main body is connected to the air inlet through a special-shaped air duct, and the mobile plasma hematopoietic stem cell transplant cabin also includes:

[0010] A plurality of closed soft curtains are arranged on each of the mounting frame plates by the first closing mechanism, and the plurality of closed soft curtains respectively correspond to the gaps between two adjacent mounting support legs. The first closing mechanism enables each of the closed soft curtains to have two motion states. In the first motion state, the closed soft curtains are unfolded downward from the mounting frame plate by the first closing mechanism; in the second motion state, after the closed soft curtains are lowered to the maximum stroke of the first closing mechanism in the vertical direction, the first closing mechanism turns over the closed soft curtains and makes the closed soft curtains in a J shape as a whole.

[0011] The hanging mechanism is arranged on each of the mounting support legs and connected to the first closing mechanism through a transmission mechanism. The first closing mechanism drives the closed soft curtain to close the gap between each of the adjacent mounting support legs through the transmission mechanism, and the hanging mechanism flips upwards at the same time;

[0012] A closed pressure plate is arranged on each of the mounting support legs through an auxiliary closing mechanism, and the auxiliary closing mechanism is connected to the transmission mechanism. When the closed soft curtain is unfolded downward and the hanging mechanism is flipped upward, the closed pressure plates are rotated toward each other through the auxiliary closing mechanism. When the hanging mechanism is flipped to the maximum stroke and the closed soft curtain is flipped to form a J shape, the auxiliary closing mechanism drives the closed pressure plate to move vertically downward, and the bent position of the J-shaped closed soft curtain is pressed against the ground.

[0013] As a further description of the above technical solution: the first closing mechanism includes a plurality of soft curtain storage rollers having the same number as the mounting frame plates, and the plurality of soft curtain storage rollers are rotatably arranged on different mounting frame plates respectively, the closed soft curtain is wound around the soft curtain storage rollers, and a closed conveyor belt and a fitting closed plate are installed on both ends of each of the mounting frames, and a pulling block fixed to the end of the closed soft curtain is arranged on the belt surface of the closed conveyor belt outside the gap between the fitting closed plate and the closed conveyor belt, and when the pulling block pulls the closed soft curtain to move downward, the closed soft curtain is made to contact the surface of the fitting closed plate through the closed conveyor belt.

[0014] As a further description of the above technical solution: the transmission mechanism includes an active rotating screw rotatably arranged in each of the mounting support legs and a first driving unit arranged between the active rotating screw and the mounting frame plate. When the active rotating screw rotates, the soft curtain storage roller and the closed conveyor belt in each of the mounting frame plates are rotated in opposite directions through the first driving unit.

[0015] As a further description of the above technical solution: the hanging mechanism includes two screws rotatably arranged on the mounting support legs and auxiliary hanging legs respectively threadedly installed on the two screws, and a second driving part is also arranged between the two screws and the main rotating shaft. When the active rotating screw rotates, the second driving part causes the two auxiliary hanging legs to rotate upward in opposite directions.

[0016] As a further description of the above technical solution: the second driving part includes two worm wheels rotatably arranged in the mounting support legs and a worm screw arranged on the outer surface of the two active rotating screw rods. When the active rotating screw rod rotates, the two worm wheels rotate simultaneously through the worm screw, and the two worm wheels are respectively connected to the two screw rods.

[0017] As a further description of the above technical solution: the end of the fitting closing plate close to the soft curtain storage roller is made of elastic material, and the end of the fitting closing plate is fitted to the surface of the soft curtain storage roller.

[0018] As a further description of the above technical solution: the auxiliary closing mechanism includes multiple groups of brackets fixedly arranged on the mounting support legs and multiple groups of screw rods rotatably arranged on the multiple groups of the brackets, and a lifting mounting block is threadedly installed on the screw rod, and a closing pressure plate is installed on the lifting mounting block through a rotating mechanism. When the actively rotating screw rod rotates, the closing pressure plate is rotated in a direction away from the mounting support leg through the rotating mechanism.

[0019] As a further description of the above technical solution: the auxiliary closing mechanism also includes a slider slidably arranged on the inner bottom surface of the mounting support leg through an elastic member, a driven drive gear disc is rotatably arranged on the surface of the slider, and a synchronous belt is installed between the driven drive gear disc and the screw rod through a synchronous wheel, an active drive gear disc is arranged on the bottom surface of the active rotating screw rod, and the auxiliary closing mechanism also includes an interference mechanism arranged between the synchronous belt and the inner wall of the mounting support leg. After the screw rod drives the auxiliary hanging leg to flip upward into place and when the screw rod continues to rotate, the interference mechanism interferes with the synchronous belt to make the driven drive gear disc engage with the active drive gear disc.

[0020] As a further description of the above technical solution: the resistance mechanism includes an adjustment block which is installed on the inner wall surface of the mounting support leg through a spring and has a slot, the auxiliary hanging leg is fixed with a connecting rod which is adapted to the slot, and the adjustment block is fixed with a resistance adjustment rod which resists the surface of the synchronous belt.

[0021] As a further description of the above technical solution: the closed pressure plate is made of elastic material, and the thickness of the closed pressure plate is smaller than the gap between the closed conveyor belt and the closed soft curtain.

[0022] In the above technical solution, the mobile plasma hematopoietic stem cell transplantation chamber provided by the present invention has the following beneficial effects:

[0023] Lightweight design reduces the difficulty of movement and installation: Compared with the traditional integral laminar flow ward, the transplant cabin adopts retractable closed soft curtain as the main closing means, which significantly reduces the overall weight, making the transplant cabin lighter and convenient for rapid movement and installation in different medical places.

[0024] Closed soft curtains can be stored to prevent damage: Closed soft curtains can be wrapped around the soft curtain storage roller when not in use, which not only avoids damage during unnecessary movement, but also ensures the cleanliness and long-term use of the soft curtains.

[0025] The closed soft curtain is closed in multiple directions to ensure the sealing effect: through the coordinated action of the closed conveyor belt, the fitted closing plate and the auxiliary closing mechanism, the closed soft curtain is closed in multiple directions, which effectively prevents the entry of external air and pollutants and ensures the sterile environment inside the transplant cabin.

[0026] Good sealing effect and improved treatment safety: The overall design is excellent and the various components work closely together, so that the transplant cabin can form a highly closed and sterile working environment after expansion, greatly improving the safety of hematopoietic stem cell transplantation. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in the present invention. For ordinary technicians in this field, other drawings can also be obtained based on these drawings.

[0028] Figure 1 A schematic diagram of the overall structure provided by an embodiment of the present invention;

[0029] Figure 2 A schematic diagram of the structure of the overall bottom view provided by an embodiment of the present invention;

[0030] Figure 3 The embodiment of the present invention provides Figure 2 The enlarged structural diagram at A in the middle;

[0031] Figure 4 A schematic diagram of the structure of the transmission mechanism and the mounting support legs provided in an embodiment of the present invention;

[0032] Figure 5 The embodiment of the present invention provides Figure 4 The enlarged structural diagram at B in the middle;

[0033] Figure 6 A schematic diagram of the structure of the mounting support legs and the auxiliary hanging legs provided in an embodiment of the present invention;

[0034] Figure 7 A schematic diagram of a partial structure of an installation support leg provided in an embodiment of the present invention;

[0035] Figure 8 A schematic diagram of the structure of an angle of the mounting support leg provided by an embodiment of the present invention;

[0036] Fig. 9 A schematic diagram of the structure of a front view of a mounting support leg provided in an embodiment of the present invention;

[0037] Fig.10 A schematic diagram of the structure of a front view and cross section of a mounting support leg provided by an embodiment of the present invention;

[0038] Fig.11 The embodiment of the present invention provides Figure 7 The enlarged structural diagram at C in the middle;

[0039] Fig.12 A schematic diagram of the structure of a bonding sealing plate provided in an embodiment of the present invention;

[0040] Fig.13 A schematic diagram of the structure of an active rotating screw provided in an embodiment of the present invention;

[0041] Fig.14A flowchart of the air flow direction provided by an embodiment of the present invention;

[0042] Fig.15 A schematic diagram of the structure of a front view section provided by an embodiment of the present invention;

[0043] Fig.16 The embodiment of the present invention provides Fig.15 Schematic diagram of the structure enlarged at point D in the middle.

[0044] Description of reference numerals:

[0045] 1. Install the support legs; 2. Air inlet; 3. Close the soft curtain; 31. Soft curtain storage roller; 32. Pull block; 33. Close the conveyor belt; 34. Fit the closed plate; 4. Special-shaped air duct; 5. Auxiliary hanging legs; 51. Screw; 52. Connecting rod; 6. Gear 1; 61. Gear 2; 62. Bevel gear disc 1; 63. Bevel gear disc 2; 64. Active rotation screw; 65. Worm; 66. Worm wheel; 7. Install the frame plate; 8. Rack; 81. Spring; 82. Closed pressure plate; 83. Gear set; 84. Lifting installation block; 85. Bracket; 86. Synchronous belt; 87. Screw; 88. Conflict adjustment rod; 89. Driven drive gear disc; 810. Sliding block; 811. Adjustment block; 812. Active drive gear disc; 9. Plasma air disinfection machine host; 10. Laminar clean hood. DETAILED DESCRIPTION

[0046] In order to enable those skilled in the art to better understand the technical solution of the present invention, the present invention will be further described in detail below with reference to the accompanying drawings.

[0047] See also Figure 1-16The embodiment of the present invention provides a technical solution: a mobile plasma hematopoietic stem cell transplantation cabin, comprising a plurality of mounting support legs 1 and a plurality of mounting frame plates 7 fixedly arranged on the mounting support legs 1, wherein the plurality of mounting frame plates 7 form a rectangular frame viewed from above, and the rectangular frame has high stability and can withstand certain external force impacts to ensure the safety of the transplantation cabin during use, and the plurality of mounting support legs 1 and the plurality of mounting frame plates 7 are integrally formed into an integral frame of the transplantation cabin, and the integral frame is a cubic structure as a whole, and the space formed in the middle is the working space for the hematopoietic stem cell transplantation cabin to perform stem cell transplantation. The mounting frame plate 7 is also provided with a plasma air disinfection machine main unit 9 for replacing air in the internal space of the overall frame, and the closed frame plate is provided with a laminar clean hood 10 with an air inlet 2. The air replacement port of the plasma air disinfection machine main unit is connected to the air inlet 2 through a special-shaped air duct, and the air purified by the plasma air disinfection main unit 9 is transported to the laminar clean hood 10 through the special-shaped air duct 4, so that the laminar clean hood 10 and the working space between the plurality of mounting support legs 1 are sterilized, providing a good environment for subsequent stem cell transplantation, characterized in that the mobile plasma hematopoietic stem cell transplantation cabin also includes:

[0048] It should be noted here that the mounting support leg 1 and the mounting frame plate 7 can also be connected in a detachable manner, which is convenient for disassembly during transportation and storage, reduces the occupied space, and is convenient for rapid on-site assembly. Among them, the fixed setting and the detachable connection are both existing technologies, and the details are not repeated here;

[0049] A plurality of groups of closed soft curtains 3 are arranged on each of the mounting frame plates 7 by the first closing mechanism, and the plurality of groups of closed soft curtains 3 respectively correspond to the gaps between two adjacent mounting support legs 1. When the mobile plasma hematopoietic stem cell transplantation cabin is moved to the installation location, the first closing mechanism enables each of the closed soft curtains 3 to have two movement states. The first movement state: the closed soft curtains 3 are unfolded downward from the mounting frame plate 7 by the first closing mechanism; at this time, the closed soft curtains 3 move downward along the surfaces of two adjacent mounting support legs 1 to close the gaps between each mounting support leg 1. The second movement state: after the closed soft curtains 3 descend to the maximum stroke of the first closing mechanism in the vertical direction, the first closing mechanism flips the closed soft curtains 3 and makes the closed soft curtains 3 J-shaped as a whole; at this time, the closed soft curtains 3 have completely closed the gaps between the mounting support legs 1, and at this time, only the bottom of the bending position of the J-shaped closed soft curtains 3 is ventilated with the outside.

[0050] The hanging mechanism is arranged on each of the mounting support legs 1 and is connected to the first closing mechanism through a transmission mechanism. The first closing mechanism drives the closed soft curtain 3 to close the gaps between the adjacent mounting support legs 1 through the transmission mechanism, and the hanging mechanism flips upwards at the same time. When the mobile plasma hematopoietic stem cell transplantation cabin is moved to the location where the cabin is to be set up and begins to be unfolded, the hanging mechanism and the first closing mechanism are moved simultaneously through the transmission mechanism. When the first closing mechanism closes the gaps between the mounting support legs 1 and gradually forms a J shape, the hanging mechanism flips upwards and moves into place. At this time, the hanging mechanism can be fixed by setting a hook at the top of the room, thereby assisting the installation and fixation of the plasma hematopoietic stem cell transplantation cabin and improving the overall stability. Not only does it enhance the overall stability of the transplantation cabin, but it can also prevent the soft curtain from shaking due to external force during use through cooperation with the closed soft curtain, thereby further ensuring the sealing effect.

[0051] The closed pressure plate 82 is arranged on each of the mounting support legs 1 through an auxiliary closing mechanism, and the auxiliary closing mechanism is connected to the transmission mechanism. When the closed soft curtain 3 is unfolded downward and the hanging mechanism is flipped upward, the closed pressure plates 82 are rotated in the direction of approaching each other through the auxiliary closing mechanism, and when the hanging mechanism is flipped to the maximum stroke and the closed soft curtain 3 is flipped to form a J shape, the auxiliary closing mechanism drives the closed pressure plate 82 to move vertically downward, and the bending position of the J-shaped closed soft curtain 3 is pressed against the ground. At this time, the bending position of the J-shaped closed soft curtain 3 is pressed against the ground through the closed pressure plate 82, and the position is closed, further reducing the air exchange between the working space and the external space between the laminar clean hood 10 and the multiple mounting support legs 1, greatly improving the aseptic cleanliness level;

[0052] The first closing mechanism includes a plurality of soft curtain storage rollers 31, the number of which is the same as the mounting frame plate 7, and the plurality of soft curtain storage rollers 31 are rotatably arranged on different mounting frame plates 7, the closed soft curtain 3 is wound around the soft curtain storage rollers 31, and a closed conveyor belt 33 and a fitting closed plate 34 are installed on both ends of each of the mounting frames, and a pull block 32 fixed to the end of the closed soft curtain 3 is arranged on the belt surface of the closed conveyor belt 33 outside the gap between the fitting closed plate 34 and the closed conveyor belt 33, when the pull block 32 pulls the closed soft curtain 3 to move downward, the closed soft curtain 3 is made to contact the surface of the fitting closed plate 34 through the closed conveyor belt 33. When the closed soft curtain 3 is pulled downward by the pull block 32 on the closed conveyor belt 33, the belt surface of the closed conveyor belt 33 presses the closed soft curtain 3 against the surface of the fitting closed plate 34, so that the side position of the closed soft curtain 3 is closed when the closed soft curtain 3 descends. That is to say, the width of the gap between the closed conveyor belt 33 and the fitting closed plate 34 needs to be smaller than the thickness of the closed soft curtain 3 to maximize the sealing effect of the lateral position of the closed soft curtain 3, and before the mobile plasma hematopoietic stem cell transplantation cabin is moved to the establishment location, the closed soft curtain 3 is stored by the soft curtain storage roller 31 to prevent the closed soft curtain 3 from being damaged and leaking when the mobile plasma hematopoietic stem cell transplantation cabin is moved, thereby improving the sealing effect. Compared with the integrated mobile plasma hematopoietic stem cell transplantation cabin, the closed soft curtain 3 is used as the main means of sealing, so that its weight is greatly reduced, which is convenient for overall movement, and also reduces costs, is convenient for large-scale use, and relieves medical pressure;

[0053] The transmission mechanism includes an active rotating screw 64 rotatably arranged in each of the mounting support legs 1 and a first driving part arranged between the active rotating screw 64 and the mounting frame plate 7. When the active rotating screw 64 rotates, the soft curtain storage roller 31 and the closed conveyor belt 33 in each of the mounting frame plates 7 are rotated in opposite directions through the first driving part;

[0054] In one embodiment of the present invention, see Figure 4 and Figure 5The first driving part includes gear 1 6, gear 2 61, bevel gear disc 1 62 and bevel gear disc 2 63, wherein gear 1 6 is installed on the rotating shaft of each closed conveyor belt 33, gear 2 61 is provided at the end of each soft curtain receiving roller 31, and gear 1 6 is meshed with gear 2 61, bevel gear disc 1 62 is fixed on each gear 2 61, two adjacent bevel gear discs 1 62 are meshed with each other, and bevel gear disc 2 63 is fixedly arranged on the end of each active rotating screw 64, bevel gear disc 2 63 is meshed with one of the two adjacent bevel gear discs 1 62, it should be noted that the driving The device is arranged in one of the mounting support legs 1 and connected to the active rotating screw 64 in the mounting support leg 1. One of the active rotating screws 64 is driven to rotate by the driving device, and the meshing structure of the bevel gear plate 1 62 and the bevel gear plate 2 63, and then the meshing action of the gear 1 6 and the gear 2 61, so that the soft curtain storage roller 31 and the closed conveyor belt 33 rotate in opposite directions, thereby pulling the closed soft curtain 3 wound on the surface of the soft curtain storage roller 31 downward, realizing overall transmission, so that the closed soft curtain 3 on each group of soft curtain storage rollers 31 is pulled downward at the same time;

[0055] Among them, the gear 1 6, the gear 2 61, the bevel gear disc 1 62 and the bevel gear disc 2 63 in the first driving part are all manufactured by high-precision processing technology, with small meshing clearance and smooth transmission, and can accurately convert the rotational motion of the active rotating screw 46 into the reverse rotational motion of each soft curtain storage roller 31 and the closed conveyor belt 33, so as to ensure the normal unfolding and folding of the closed soft curtain 3;

[0056] The hanging mechanism includes two screws 51 rotatably arranged on the mounting support leg 1 and auxiliary hanging legs 5 respectively threadedly arranged on the two screws 51. A second driving part is also arranged between the two screws 51 and the main rotating shaft. When the active rotating screw 64 rotates, the second driving part makes the two auxiliary hanging legs 5 rotate upward in opposite directions.

[0057] When the active rotating screw 64 is rotated by the driving device, the two auxiliary hanging legs 5 are rotated upward in opposite directions by the second driving part via the two screws 51, and then the two flipped auxiliary hanging legs 5 are fixed to the roof position to increase the overall stability of the mobile plasma hematopoietic stem cell transplantation chamber after movement;

[0058] It should be noted that the second driving part includes two worm wheels 66 rotatably arranged in the mounting support leg 1 and a worm 65 arranged on the outer surface of the two active rotating screws 64. When the active rotating screw 64 rotates, the two worm wheels 66 rotate simultaneously through the worm 65, and the two worm wheels 66 are respectively connected to the two screws 51. When the active rotating screw rod 64 rotates, the two worm wheels 66 rotate through the worm 65, thereby rotating the two screw rods 51. Since the two auxiliary hanging legs 5 are not subject to any position restriction at this time, the friction between the screws of the auxiliary hanging legs 5 and the screw rods 51 makes the two auxiliary hanging legs 5 and the screw rods 51 in a relatively fixed state, so that the screw rods 51 at this time make the two auxiliary hanging legs 5 flip upward through the threaded structure with the two auxiliary hanging legs 5, and then the auxiliary hanging legs 5 can be fixed to the roof position to increase the overall stability after installation. The installation method can be to hang the auxiliary hanging legs 5 on the roof hooks in the hanging grooves, or to fix the auxiliary hanging legs 5 to the roof surface by bolts. Such installation methods are all existing technologies and will not be described in detail here.

[0059] It should also be noted that, for different roof structures, the ends of the auxiliary hanging legs 5 are designed with a variety of connection methods, such as the hook-hanging type is suitable for roofs with ceiling keels, and the bolt-fixed type is suitable for roofs with steel beam structures. It can be installed conveniently and quickly in various practical use scenarios, enhancing the installation method and adaptability of the hanging mechanism and improving practicality.

[0060] The end of the fitting closing plate 34 close to the soft curtain storage roller 31 is made of elastic material, and the end of the fitting closing plate 34 fits the surface of the soft curtain storage roller 31. When the closed soft curtain 3 is pulled downward by the pull block 32 on the closed conveyor belt 33, as the closed soft curtain 3 on the soft curtain storage roller 31 is gradually released, the closed soft curtain 3 wound on the soft curtain storage roller 31 gradually decreases, and the overall diameter decreases. At this time, the end of the fitting closing plate 34 made of elastic material gradually recovers its deformation and continues to fit the surface of the soft curtain storage roller 31, thereby preventing the closed soft curtain 3 on the soft curtain storage roller 31 from being gradually released and causing the diameter of the soft curtain storage roller 31 to change, which may cause air leakage. In order to further enhance this effect, please refer to Fig.12 A bonding plate made of the same material as the end of the bonding sealing plate 34 is also fixedly arranged on the side of the mounting frame plate 7 away from the bonding sealing plate 34, so that after the closed soft curtain 3 on the soft curtain storage roller 31 is gradually released, the bonding plate continues to be bonded to the surface of the soft curtain storage roller 31 to prevent air leakage between the mounting frame plate 7 and the soft curtain storage roller 31;

[0061] The auxiliary closing mechanism includes a plurality of brackets 85 fixedly arranged on the mounting support leg 1 and a plurality of screws 87 rotatably arranged on the plurality of brackets 85. A lifting mounting block 84 is threadedly mounted on the screw 87. A closing pressure plate 82 is mounted on the lifting mounting block 84 through a rotating mechanism. When the active rotating screw 64 rotates, the closing pressure plate 82 is rotated in a direction away from the mounting support leg 1 through the rotating mechanism. In one embodiment of the present invention, the rotating mechanism includes a mutually meshing gear set 83 rotatably arranged on the lifting mounting block 84 and a rack 8 threadedly mounted on the active rotating screw 64 and slidably connected to the inner wall surface of the mounting support leg 1. When the active rotating screw 64 rotates, the rack 8 moves on the active rotating screw 64 until the rack 8 meshes with one of the gears in the gear set 83. The closing pressure plate 82 is fixedly arranged on one of the gears in the gear set 83. The continuous descent of the rack 8 drives the gear set 83 to rotate, thereby rotating the closing pressure plate 82 in a direction away from the mounting support leg 1.

[0062] In another embodiment of the present invention, the auxiliary closing mechanism also includes a slider 810 slidably arranged on the inner bottom surface of the mounting support leg 1 through an elastic member, and a driven drive gear disc 89 is rotatably arranged on the surface of the slider 810, and a synchronous belt 86 is installed between the driven drive gear disc 89 and the screw rod 87 through a synchronous wheel, and an active drive gear disc 812 is arranged on the bottom surface of the active rotating screw rod 64, and the auxiliary closing mechanism also includes an interference mechanism arranged between the synchronous belt 86 and the inner wall of the mounting support leg 1. After the screw rod 51 drives the auxiliary hanging leg 5 to flip upward into place and when the screw rod 51 continues to rotate, the interference mechanism interferes with the synchronous belt 86 to make the driven drive gear disc 89 engage with the active drive gear disc 812. When the active rotating screw 64 continues to rotate, the two screws 51 drive the two auxiliary hanging legs 5 to flip upward through the worm 65 and the worm wheel 66, until the two auxiliary hanging legs 5 flip to fit each other, at this time, the two auxiliary hanging legs 5 still have a relative rotation tendency, but due to the mutual conflict, they are limited. At this time, under the rotation of the screw 51, the auxiliary hanging leg 5 will move on the screw 51 through the threaded structure with the screw 51; the elastic member is a spring leaf or a hydraulic column, which are both existing technologies and will not be described in detail here;

[0063] The resistance mechanism includes an adjustment block 811 which is installed on the inner wall surface of the mounting support leg 1 through a spring 81 and has a slot. The auxiliary hanging leg 5 is fixedly provided with a connecting rod 52 adapted to the slot. When the two auxiliary hanging legs 5 rotate upward and conflict with each other, the connecting rod 52 is inserted into the slot. At this time, as the screw 51 rotates, the two auxiliary hanging legs 5 move on the screw 51, thereby pushing the adjustment block 811 to move through the connecting rod 52. At this time, the spring 81 is stretched and deformed. The adjustment block 811 is fixedly provided with a conflict adjustment rod 88 that conflicts with the surface of the synchronous belt 86. When the adjustment block 811 moves , through the friction adjustment rod 88 against the synchronous belt 86, the synchronous belt 86 pulls the driven drive gear disc 89 toward the active drive gear disc 812 until the driven drive gear disc 89 is engaged with the active drive gear disc 812. At this time, the screw rod 87 is rotated by the synchronous belt 86, so that the lifting mounting block 84 moves downward through the threaded structure with the screw rod 87, realizing the downward movement of the closed pressure plate 82, so that the closed pressure plate 82 rotates for a period of time and then moves downward on this basis, so that the bending position of the J-shaped closed soft curtain 3 is abutted against the ground through the closed pressure plate 82 to form a closure.

[0064] It should be noted that two closed pressing plates 82 are arranged on each mounting support leg 1, so there will also be two synchronous belts 86. Here, it is only necessary to stagger the two synchronous belts 86 in height to prevent interference, and the length of the screw rod 87 is set to: the gap size between the lifting mounting block 84 and the synchronous belt 86, that is, the size that the lifting mounting frame can drive the closed pressing plate 82 to descend needs to meet the closed pressing plate 82 to form a conflict with the J-shaped closed soft curtain 3;

[0065] It should also be noted that the overall closing process is to assemble the mounting support leg 1 and the mounting frame plate 7 at the specified position, connect the plasma air disinfection machine main unit 9 with the special-shaped air duct 4 and the laminar clean hood 10, and then drive one of the active rotating screws 64 to rotate through the driving device, and then through the transmission mechanism, the soft curtain storage roller 31 and the closed conveyor belt 33 in each mounting frame plate 7 are rotated in opposite directions, so that the closed soft curtain 3 is pulled downward. At the same time, the two auxiliary hanging legs 5 are flipped upward, and the rack 8 moves downward on the active rotating screw 64 until the rack 8 is engaged with one of the gears in the gear set 83, so that the closed pressure plate 82 is rotated a certain angle away from the mounting support leg 1 to leave space for subsequent downward pressure. This process continues until the auxiliary hanging leg 5 When the closed soft curtain 3 is flipped upwards to contact each other and deflected upwards and gradually becomes J-shaped under the drive of the closed conveyor belt 33, the contact adjustment rod 88 contacts the synchronous belt 86, the driven drive gear plate 89 is meshed with the active drive gear plate 812, the screw rod 87 rotates, and the lifting mounting block 84 drives the closed pressing plate 82 to move downward. At this time, the closed pressing plate 82 rotates in the direction close to the ground and moves parallel to the ground until the J-shaped closed soft curtain 3 is contacted to the ground through the closed pressing plate 82, thereby realizing the entire closing process. When the closed soft curtain 3 is used, the inside and outside of the mobile plasma hematopoietic stem cell transplantation cabin can be automatically closed, the whole weight is light, the overall movement is convenient, the actual use effect is better, and the entire process is automatically controlled through the ingenious cooperation of the mechanical structure and the transmission components;

[0066] In order to facilitate the closed soft curtain 3 to be pressed against the ground by the closed pressure plate 82, the closed pressure plate 82 is made of elastic material, and the thickness of the closed pressure plate 82 is smaller than the gap between the closed conveyor belt 33 and the closed soft curtain 3. When the closed soft curtain 3 is turned over by the closed conveyor belt 33 and becomes J-shaped, the closed pressure plate 82 can be inserted into the gap between the closed conveyor belt 33 and the closed soft curtain 3, and when the closed pressure plate 82 is continuously pressed down, the bending position of the J-shaped closed soft curtain 3 is pressed against the ground. The elastic material ensures that the closed pressure plate 82 has a certain elasticity, which can not only improve the overall sealing effect after the closed soft curtain 3 is pressed against the ground, but also make the closed pressure plate 82 have a certain elasticity, so that the whole has a certain buffer, which is convenient for practical use. In order to further improve the sealing effect, the end of the closed pressure plate 82 is constructed as a convex structure that fits the J-shaped closed soft curtain 3, so that the closed soft curtain 3 and the ground fit tightly, forming a multi-level sealing structure, effectively blocking the entry of external pollutants;

[0067] The closed soft curtain 3 is made of PEVA material, and the soft curtain storage roller 31 is made of high-strength aluminum alloy, and the surface is anodized, which has good wear resistance and corrosion resistance, ensuring that the closed soft curtain 3 can be stably stored and released during long-term use;

[0068] To summarize, after the internal working space of the mobile plasma hematopoietic stem cell transplantation cabin is sealed, the air replacement rate of the working space is adjusted between 150-280 times / h through the mobile plasma hematopoietic stem cell transplantation cabin, and the dynamic class 100 laminar flow aseptic cleanliness level is maintained, finally completing all the work of the mobile plasma hematopoietic stem cell transplantation cabin.

[0069] The above description is only by way of illustration of certain exemplary embodiments of the present invention. It is undoubted that those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the above drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. A mobile plasma hematopoietic stem cell transplantation cabin, comprising a plurality of mounting support legs (1) and a plurality of mounting frame plates (7) fixedly arranged on the mounting support legs (1), wherein the plurality of mounting frame plates (7) form a rectangular frame when viewed from above, and the plurality of mounting support legs (1) and the plurality of mounting frame plates (7) are integrally formed into an integral frame of the transplantation cabin, a plasma air sterilizer main body (9) for replacing air in the internal space of the integral frame is also arranged on the plurality of mounting frame plates (7), a laminar clean hood (10) with an air inlet (2) is arranged on the closed frame plate, and the air replacement port of the plasma air sterilizer main body (9) is connected to the air inlet (2) through a special-shaped air duct, characterized in that: The mobile plasma hematopoietic stem cell transplantation chamber also includes: A plurality of groups of closed soft curtains (3) are arranged on each of the mounting frame plates (7) by means of a first closing mechanism, and the plurality of groups of closed soft curtains (3) respectively correspond to the gaps between two adjacent mounting support legs (1). The first closing mechanism enables each of the closed soft curtains (3) to have two motion states. In the first motion state, the closed soft curtains (3) are unfolded downward from the mounting frame plate (7) by means of the first closing mechanism. In the second motion state, after the closed soft curtains (3) are lowered to the maximum stroke of the first closing mechanism in the vertical direction, the first closing mechanism causes the closed soft curtains (3) to flip over, and the closed soft curtains (3) are formed into a J shape as a whole. A hanging mechanism is arranged on each of the mounting support legs (1) and is connected to the first closing mechanism via a transmission mechanism, and the first closing mechanism drives the closed soft curtain (3) to close the gap between each of the adjacent mounting support legs (1) via the transmission mechanism, while the hanging mechanism flips upwards; A closed pressure plate (82) is arranged on each of the mounting support legs (1) through an auxiliary closing mechanism, and the auxiliary closing mechanism is connected to the transmission mechanism. When the closed soft curtain (3) is unfolded downward and the hanging mechanism is flipped upward, the closed pressure plates (82) are rotated in a direction approaching each other through the auxiliary closing mechanism. When the hanging mechanism is flipped to the maximum stroke and the closed soft curtain (3) is flipped to form a J shape, the auxiliary closing mechanism drives the closed pressure plate (82) to move vertically downward, and the bent position of the J-shaped closed soft curtain (3) is pressed against the ground.

2. A mobile plasma hematopoietic stem cell transplantation chamber according to claim 1, characterized in that: The first closing mechanism comprises a plurality of soft curtain storage rollers (31) the same number as the mounting frame plate (7), and the plurality of soft curtain storage rollers (31) are rotatably arranged on different mounting frame plates (7), the closed soft curtain (3) is wound around the soft curtain storage rollers (31), and a closed conveyor belt (33) and a fitting closed plate (34) are installed on both ends of each mounting frame, and a pull block (32) fixed to the end of the closed soft curtain (3) is arranged on the belt surface of the closed conveyor belt (33) outside the gap between the fitting closed plate (34) and the closed conveyor belt (33), and when the pull block (32) pulls the closed soft curtain (3) to move downward, the closed soft curtain (3) is made to contact the surface of the fitting closed plate (34) through the closed conveyor belt (33).

3. The mobile plasma hematopoietic stem cell transplantation chamber according to claim 1, characterized in that: The transmission mechanism comprises an active rotating screw (64) rotatably arranged in each of the mounting support legs (1) and a first driving unit arranged between the active rotating screw (64) and the mounting frame plate (7). When the active rotating screw (64) rotates, the soft curtain storage roller (31) and the closed conveyor belt (33) in each of the mounting frame plates (7) are caused to rotate in opposite directions through the first driving unit.

4. The mobile plasma hematopoietic stem cell transplantation chamber according to claim 1, characterized in that: The hanging mechanism comprises two screw rods (51) rotatably arranged on the mounting support leg (1) and auxiliary hanging legs (5) respectively threadedly mounted on the two screw rods (51). A second driving part is also arranged between the two screw rods (51) and the main rotating shaft. When the active rotating screw rod (64) rotates, the second driving part causes the two auxiliary hanging legs (5) to rotate upward in opposite directions.

5. The mobile plasma hematopoietic stem cell transplantation chamber according to claim 1, characterized in that: The second driving part comprises two worm wheels (66) rotatably arranged in the mounting support leg (1) and a worm (65) arranged on the outer surface of two active rotating screws (64); when the active rotating screw (64) rotates, the two worm wheels (66) are rotated simultaneously through the worm (65); the two worm wheels (66) are respectively connected to the two screws (51).

6. The mobile plasma hematopoietic stem cell transplantation chamber according to claim 1, characterized in that: The end of the fitting closing plate (34) close to the soft curtain storage roller (31) is made of elastic material, and the end of the fitting closing plate (34) fits on the surface of the soft curtain storage roller (31).

7. The mobile plasma hematopoietic stem cell transplantation chamber according to claim 1, characterized in that: The auxiliary sealing mechanism comprises a plurality of brackets (85) fixedly arranged on the mounting support legs (1) and a plurality of screw rods (87) rotatably arranged on the plurality of brackets (85); a lifting mounting block (84) is threadedly mounted on the screw rods (87); a sealing pressure plate (82) is mounted on the lifting mounting block (84) via a rotating mechanism; when the active rotating screw rod (64) rotates, the sealing pressure plate (82) is rotated in a direction away from the mounting support legs (1) via the rotating mechanism.

8. The mobile plasma hematopoietic stem cell transplantation chamber according to claim 1, characterized in that: The auxiliary sealing mechanism also includes a slider (810) slidably arranged on the inner bottom surface of the mounting support leg (1) through an elastic member, a driven drive toothed disc (89) is rotatably arranged on the surface of the slider (810), and a synchronous belt (86) is installed between the driven drive toothed disc (89) and the screw rod (87) through a synchronous wheel, and an active drive toothed disc (812) is arranged on the bottom surface of the active rotating screw rod (64), and the auxiliary sealing mechanism also includes a resistance mechanism arranged between the synchronous belt (86) and the inner wall of the mounting support leg (1), and after the screw rod (51) drives the auxiliary hanging leg (5) to flip upward into place and when the screw rod (51) continues to rotate, the resistance mechanism resists the synchronous belt (86) to make the driven drive toothed disc (89) mesh with the active drive toothed disc (812).

9. The mobile plasma hematopoietic stem cell transplantation chamber according to claim 1, characterized in that: The abutment mechanism comprises an adjustment block (811) which is mounted on the inner wall surface of the mounting support leg (1) via a spring (81) and is provided with a notch; a connecting rod (52) which is adapted to the notch is fixedly provided on the auxiliary hanging leg (5); and an abutment adjustment rod (88) which abuts against the surface of the synchronous belt (86) is fixedly provided on the adjustment block (811).

10. The mobile plasma hematopoietic stem cell transplantation chamber according to claim 1, characterized in that: The closed pressing plate (82) is made of elastic material, and the thickness of the closed pressing plate (82) is smaller than the gap between the closed conveyor belt (33) and the closed soft curtain (3).

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