Method for purifying abamectin crystal
By using methanol with a pH of 4.0-6.5 and a mass concentration of 80-95% during the purification process of avermectin crystal, the problem of poor clarity of avermectin crystals was solved, the product purity and yield were improved, the production cost was reduced, and the operation process was simplified.
Patent Information
- Application Number
- CN202510870120.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-06-26
- Publication Date
- 2025-08-05
AI Technical Summary
In the prior art, the crystal clarity of avermectin is poor, the composite solvent crystallization method is sensitive to crystal form and particle size distribution, and it is difficult to meet the purity and appearance requirements of high-end preparations. It is difficult to recover the solvent, high cost, and high environmental pressure.
Methanol with a pH of 4.0-6.5 and a mass concentration of 80-95% was used for three and four crystals. By changing the charge distribution of crystals and impurities, the presence of water reduces the volatility rate of solvents, selectively removes impurities that affect clarity, and improves the purity and yield of avermectin crystals.
It significantly improves the clarity of avermectin crystals, improves product quality, reduces production costs, simplifies operating procedures, and has good economic and social benefits.