Biological tissue sample preservation box

Abstract

The invention relates to the field of biological sample culture, and particularly discloses a biological tissue sample preservation box, which comprises a storage box, which comprises box walls and a cavity defined by the box walls; the supporting piece is fixedly arranged in the cavity to support a test tube in which a specimen is stored; the extracting device is used for placing the test tube on the supporting piece and taking the test tube from the supporting piece; wherein the box wall forms an opening entering the internal space of the cavity; a sealing cover is fixedly arranged on the storage box to completely cover the cavity; a plurality of positioning grooves corresponding to the test tubes are formed in the supporting piece; the extraction device comprises an extraction pipe and a conveying belt; the extraction tube is provided with a transmission channel for guiding the test tube to get close to / away from the supporting piece along a first direction formed by the transmission channel; the conveying belt is arranged in the conveying channel and used for providing power for moving the test tubes; the biological tissue sample preservation box has the beneficial effect that the preservation environment cannot be affected during extraction.

Description

Technical Field

[0001] The present application relates to the field of biological sample culture, and in particular to a biological tissue sample storage box. Background Art

[0002] After medical staff collect biological samples, they need to be transported to the testing department for culture and testing. Some of the journeys and times for testing may be long, and the biological tissue samples need to be cultured during transportation to achieve long-term preservation. Therefore, a constant temperature box is used to preserve the biological tissue samples to ensure their activity. However, in some special cases, such as when biological tissue samples need to be obtained multiple times outdoors, the incubator needs to be opened repeatedly to store multiple samples. In this case, each time the incubator is opened, the storage environment inside the incubator is affected by the outside world. In particular, when there is a large difference between the outside temperature and the temperature and humidity inside the incubator, each time the incubator is opened, the outside temperature will directly cause the temperature and humidity inside the incubator to change. Therefore, there is a need for a biological tissue sample storage box that can be extracted without affecting the storage conditions. Summary of the Invention

[0003] In order to improve the above-mentioned problem of affecting the storage conditions when extracting biological tissue samples, the present application provides a biological tissue sample storage box.

[0004] The present application provides a biological tissue sample storage box, which adopts the following technical solutions: A storage box comprising a box wall and a cavity defined by the box wall; A support member, fixedly disposed in the cavity to support the test tube containing the specimen; an extraction device for placing the test tube onto the support and removing the test tube from the support; Among them, the box wall forms an opening to the internal space of the cavity; a sealing cover is fixedly arranged on the storage box to completely cover the cavity; the support member forms a number of positioning grooves corresponding to the test tubes; the extraction device includes: an extraction tube and a conveyor belt; the extraction tube has a transmission channel to guide the test tube to approach / move away from the support member along the first direction formed by the transmission channel; the extraction tube forms an extraction port entering the interior of the transmission channel, and the extraction port has an end cap to seal the transmission channel; the conveyor belt is arranged in the transmission channel to provide power for moving the test tube.

[0005] When in use, the test tube is placed in the transmission channel defined by the extraction tube and sealed by the end cover, and is directly placed in the positioning groove under the guidance of the transmission channel; due to the setting of the extraction tube, the positioning groove can be directly connected to the outside world and isolated from other spaces in the cavity; the setting of the conveyor belt can automatically transport the test tube after the extraction port is closed by the end cover.

[0006] Optionally, the extraction device further comprises: A loading member is disposed in the positioning groove to clamp the test tube; A magnetic block is fixedly arranged on one end of the loading part close to the extraction tube; A first electromagnet is fixedly mounted on the support member and located on the extraction tube; The inner wall of the positioning groove forms a guide groove for guiding the loading part to approach or move away from the extraction pipe.

[0007] Optionally, an elastic member is provided between the loading member and the inner wall of the positioning groove; The elastic member always exerts a pulling force on the loading member to move it away from the extraction tube.

[0008] Optionally, a pulley in contact with the surface of the connecting piece is provided at the bottom of the extraction tube; The pulley is connected to the bottom of the extraction pipe through an elastic plate.

[0009] Optionally, there are a plurality of positioning grooves, which are arranged in a circular pattern on the surface of the support member; A slide rail is formed on the surface of the support member, and the slide rail is used to guide the pulley to move along the distribution track of the positioning groove.

[0010] Optionally, there are at least two conveyor belts, which are arranged opposite to each other in the radial direction of the conveyor channel; A power wheel is rotatably arranged in the transmission channel, and a transmission belt is sleeved on the power wheel to enable the transmission belt to rotate; Among them, one transmission belt corresponds to two power wheels, and the two power wheels are distributed up and down along the first direction.

[0011] Optionally, the power wheel close to the positioning groove can reciprocate along the radial direction of the transmission channel; Among them, the inner wall of the transmission channel forms a movable groove for the power wheel close to the positioning groove to move; a slider is movably set in the movable groove, and the slider is rotationally connected to the power wheel; the slider is connected to the inner wall of the movable groove by a first elastic member.

[0012] Optionally, a rotating plate is provided on the sealing cover; An extraction port corresponding to the extraction tube is formed on the rotating plate.

[0013] Optionally, the support plate is connected to the inner wall of the cavity via a buffer assembly, and the buffer assembly includes: A support ring is provided on the inner wall of the cavity; A connecting piece, used for connecting the support ring and the support piece; The shock absorber is arranged on the inner wall of the cavity to support the support ring.

[0014] Optionally, a temperature and humidity controller is also included, which is electrically connected to the central controller to control the temperature and humidity in the cavity.

[0015] In summary, the present application provides a biological tissue sample storage box that can extract biological samples without affecting the storage environment. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is a schematic diagram of the overall structure of Example 1 of the present application; Figure 2 is a half-section schematic diagram of Example 1 of the present application; Figure 3 yes Figure 2 Enlarged view of point A in the middle; Figure 4 This is a schematic diagram of the installation of the support member in Example 1 of the present application; Figure 5 is a schematic diagram of the extraction tube and the support member in Example 1 of the present application; Figure 6 This is a half-section schematic diagram of the extraction tube in Example 1 of the present application; Figure 7 This is a schematic diagram of the extraction tube and the conveyor belt in Example 1 of the present application; Figure 8 is a schematic diagram of the slider and the first elastic member in the first embodiment of the present application; Figure 9 This is a schematic diagram of the pushing member and the second electromagnet in Example 1 of the present application.

[0017] Figure numerals: 1. storage box; 2. support member; 3. cavity; 4. opening; 5. sealing cover; 6. positioning groove; 7. support ring; 8. connecting member; 9. shock absorber; 10. embedded groove; 11. extraction tube; 12. transmission belt; 13. transmission channel; 15. power wheel; 16. moving groove; 17. slider; 18. first elastic member; 19. loading member; 20. magnetic block; 30. first electromagnet; 31. second elastic member; 32. slide rail; 33. pulley; 34. elastic sheet; 35. rotating disk; 36. pushing member; 37. return spring; 38. second electromagnet; 39. magnetic conductive member; 40. buffer member. DETAILED DESCRIPTION

[0018] Embodiments of the present disclosure will be described in more detail below with reference to the accompanying drawings. Although certain embodiments of the present disclosure are shown in the accompanying drawings, it should be understood that the present disclosure can be implemented in various forms and should not be construed as being limited to the embodiments described herein. On the contrary, these embodiments are provided to provide a more thorough and complete understanding of the present disclosure. It should be understood that the drawings and embodiments of the present disclosure are for illustrative purposes only and are not intended to limit the scope of protection of the present disclosure.

[0019] It should also be noted that, for ease of description, only the parts related to the invention are shown in the drawings. In the absence of conflict, the embodiments and features in the embodiments of the present disclosure may be combined with each other.

[0020] It should be noted that the concepts of "first" and "second" mentioned in this disclosure are only used to distinguish different devices, modules or units, and are not used to limit the order or interdependence of the functions performed by these devices, modules or units.

[0021] It should be noted that the modifications of "one" and "multiple" mentioned in the present disclosure are illustrative rather than restrictive, and those skilled in the art should understand that unless otherwise clearly indicated in the context, they should be understood as "one or more".

[0022] The present disclosure will be described in detail below with reference to the accompanying drawings and in conjunction with embodiments. Example 1

[0023] Reference Figures 1 to 9 The embodiment of the present application discloses a biological tissue sample storage box, comprising: a storage box 1, a support member 2, and an extraction device; specifically, the storage box 1 is a cylindrical box body constructed by a box wall, and has a cavity 3 defined by the box wall; an insulation layer is arranged between the inner wall of the cavity 3 and the outer wall of the box to provide the cavity 3 with insulation function, and the filling material of the insulation layer can be any one of rock wool, polyurethane foam, glass wool and aluminum silicate; the box wall has an opening 4 to enter the internal space of the cavity 3, and a sealing cover 5 is fixedly arranged at the opening 4 to completely cover the opening 4, so that the cavity 3 is in a sealed state; the fixing method adopts a threaded connection method, and the sealing cover 5 and the opening 4 have a sealing strip to achieve a sealing effect, and the inner wall of the cavity 3 is provided with a support member 2 for supporting a test tube containing a specimen, and the support member 2 is made of an acrylic plate and has a disc shape; specifically, a surface of the support member 2 forms a plurality of positioning grooves 6 corresponding to the test tube, and the test tube can be placed in the positioning groove 6 to keep the test tube away from the bottom of the cavity 3; Among them, the side wall of the support member 2 and the inner wall of the cavity 3 are fixedly connected by a buffer assembly so that the test tube can be buffered and protected during transportation; the buffer assembly includes: a support ring 7, a connector 8, and a shock absorber 9; the inner wall portion of the cavity 3 is concave in the radial direction, and the concave portion extends along the circumferential direction of the box to form an embedded groove 10 corresponding to the support ring 7; the support ring 7 is installed in the embedded groove 10, and the upper and lower walls of the support ring 7 are spaced apart from the upper and lower inner walls of the embedded groove 10; the support ring 7 is connected to the support member 2 by a connector 8, and the connector 8 is made of rubber; specifically One side of the connecting member 8 is embedded in the inner wall of the support ring 7, and the other side is embedded in the support member 2; the connecting member 8 has a buffering performance, which can provide buffering protection for the specimen when the specimen is operated; wherein, the shock absorber 9 is arranged on the bottom wall of the embedded groove 10, and the shock absorber 9 is used to support the support ring 7; the shock absorber 9 can be purchased directly on the market; through the setting of the above scheme, when the specimen is operated, when encountering vibration, the shock absorber 9 will first absorb the vibration and reduce the vibration amplitude; at this time, the vibration wave after the vibration will be absorbed by the connecting member 8 when passing through the connecting member 8, so that the vibration transmitted to the support member 2 will be lower.

[0024] In another more specific embodiment, an extraction device for taking a test tube is provided in the cavity 3, and the extraction device includes: an extraction tube 11 and a conveyor belt 12 for extracting the tube 11; wherein the extraction tube 11 is fixedly provided on the sealing cover 5, forming a transmission channel 13 corresponding to the positioning groove 6, and the transmission channel connects the cavity 3 with the outside; the test tube can be transferred to the outside of the cavity 3 through the transmission channel 13 for extraction; the test tube can also be placed from the outside into the positioning groove 6 through the transmission channel 13; the conveyor belt 12 for extracting the tube 11 is provided on the inner wall of the transmission channel 13 to give the test tube a force to move away from / close to the positioning groove 6; Specifically, two conveyor belts 12 for extracting tubes 11 are set in the same transmission channel 13, and are arranged opposite to each other in the diameter direction of the transmission channel 13. When the test tube is transmitted, the test tube is clamped in the middle by the two conveyor belts 12 for extracting tubes 11. A power wheel 15 is rotatably set on the inner wall of the transmission channel 13, and each conveyor belt 12 for extracting tubes 11 corresponds to two power wheels 15 and is distributed up and down along a first direction, and the first direction is the direction defined by the first straight line L in the figure. The power wheel 15 is driven to rotate by a motor. With this arrangement, the central processing unit controls the motor to drive the power wheel 15 to rotate, and when the test tube contacts the conveyor belt 12 for extracting tubes 11, the test tube can be moved along the first direction.

[0025] More specifically, a movable groove 16 is formed on the inner wall of the transmission channel 13, and the movable groove 16 extends along the diameter direction of the transmission channel 13; a slider 17 is slidingly set in the movable groove 16, and the slider 17 is rotationally connected to the power wheel 15 near the positioning groove 6; wherein, the slider 17 and the inner wall of the movable groove 16 are connected by a first elastic member 18, and the first elastic member 18 is a spring that can always give the two sliders 17 an elastic force to approach each other; it can be understood that the surface spacing between the two conveyor belts 12 extracting the tube 11; is always smaller than the diameter of the test tube; when transmission is required, after the conveyor belt 12 extracts the tube 11; near one end of the test tube and contacts the test tube, since the diameter of the test tube is greater than the spacing between the two conveyor belts 12 extracting the tube 11;, under the action of the first elastic member 18, the two conveyor belts 12 extracting the tube 11; will give a supporting force to the test tube, thereby extracting the test tube from the loading part 19.

[0026] In another more specific embodiment, the extraction device further includes: a loading member 19, a magnetic block 20, and a first electromagnet 30. Specifically, the loading member 19 is an acrylic plate and is movably disposed within the positioning groove 6. Specifically, a guide groove is formed on the inner wall of the positioning groove 6. The side wall of the loading member 19 is partially raised, and the raised portion is inserted into the guide groove so that the loading member 19 can move toward or away from the extraction tube 11 along the guide direction of the guide groove. A second elastic member 31 is disposed between the loading member 19 and the inner wall of the positioning groove 6. The second elastic member 31 is a tension spring that constantly applies a pulling force to the loading member 19 away from the extraction tube 11. Among them, the magnetic block 20 is a metal block with magnetic conductivity, which is fixedly set on one end of the loading part 19 close to the extraction tube 11; the first electromagnet 30 is set at the end of the extraction tube 11 close to the loading part 19; the first electromagnet 30 is electrically connected to the central processing unit, and the central processing unit is used to control the power on / off of the first electromagnet 30; it can be understood that when the first electromagnet 30 is energized, it generates magnetism that can attract the magnetic block 20 close to the extraction tube 11.

[0027] In another more specific embodiment, a slide rail 32 is formed on the surface of the support member 2, and the slide rail 32 extends along the annular array track of the positioning groove 6; a pulley 33 corresponding to the slide rail 32 is provided at the end of the extraction tube 11 close to the support member 2, and the pulley 33 can roll along the extension direction of the slide rail 32, which can effectively improve the stability of the movement of the extraction tube 11; specifically, an elastic sheet 34 is provided at the end of the extraction tube 11 close to the support member 2, and the elastic sheet 34 is in an arc shape and is made of spring steel, and the pulley 33 is rotatably connected to the elastic sheet 34.

[0028] More specifically, a rotating disk 35 is rotatably provided on the sealing cover 5; wherein, a rotating groove is formed on the surface of the sealing cover 5, and the rotating disk 35 is rotatably provided on the inner wall of the rotating groove; there is a through hole on the rotating disk 35, and the extraction tube 11 passes through the through hole to the cavity 3; the extraction tube 11 and the side wall of the through hole are sealed by sealant to prevent the internal environment of the cavity 3 from being disturbed by the outside world; more specifically, the end of the extraction tube 11 away from the support member 2 protrudes from the surface of the sealing cover 5, and the protruding part is provided with an end cover to completely seal the transmission channel 13; it is ensured that after the end cover seals the transmission channel 13, the cavity 3 can be completely sealed. Example 2

[0029] The extraction device includes a pusher 36, a return spring 37, a second electromagnet 38, a magnetic conductive member 39, and a buffer 40. Specifically, the inner wall of the positioning groove 6 is coplanar with the inner wall of the transmission channel 13. The pusher 36 is used to load the test tube and is made of an acrylic plate. It is movably mounted on the inner wall of the positioning groove 6 and can be moved into the transmission channel 13. The inner wall of the positioning groove 6 forms a step, and a return spring 37 is provided between the pusher 36 and the step. The return spring 37 can always apply a pulling force to the pusher 36 close to the step. Specifically, the second electromagnet 38 is fixedly disposed on the inner wall of the positioning groove 6 and is located at the lower end surface of the step; the second electromagnet 38 is electrically connected to the central processing unit, and the central processing unit is used to control the current of the second electromagnet 38 to control the magnetic force of the second electromagnet 38; wherein, the magnetic conductive member 39 is a permanent magnet, which is disposed on the push member 36 and is arranged opposite to the second electromagnet 38; the magnetism generated by the second electromagnet 38 after power is applied resonates with the magnetic conductive member 39; it can be understood that when the second electromagnet 38 is powered, the magnetic field generated by the second electromagnet 38 and the magnetic attraction member are of the same polarity and repel each other, which can drive the push member 36 to move up into the transmission channel 13, thereby realizing the extraction of the test tube; when the test tube needs to be placed, the central processing unit reduces the current and thus reduces the magnetic force, so that the push member 36 can be slowly reset; Among them, the buffer member 40 is a buffer belt, which has two, and is relatively arranged on the inner wall of the transmission channel 13 along the diameter direction of the transmission channel 13; specifically, the buffer belt is rotatably set on the inner wall of the transmission channel 13 away from the support member 2; the buffer belt is made of rubber, and a rotating shaft is rotatably set on the inner wall of the transmission channel 13; the buffer belt is sleeved on the rotating shaft; the rotating shaft is connected to the inner wall of the transmission channel 13 through a damping bearing; when the pushing member 36 moves to the buffer belt, it is decelerated by friction and then a shock absorption effect can be achieved under the action of the damping bearing.

[0030] In the description of the present invention, it should be noted that, unless otherwise expressly specified or limited, the terms "mounted," "connected," and "connected" should be understood in a broad sense. For example, they may refer to fixed connections, detachable connections, or integral connections; mechanical connections or electrical connections; direct connections or indirect connections through an intermediate medium; and internal communication between two components. Those skilled in the art will understand the specific meanings of the above terms in the present invention based on the specific circumstances.

[0031] The above descriptions are merely embodiments of the present invention and are not intended to limit the patent scope of the present invention. Any equivalent structure or equivalent process transformation made using the contents of the present invention description and drawings, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the present invention.

Claims

1. A biological tissue sample storage box, characterized in that: include: A storage box comprising a box wall and a cavity defined by the box wall; a support member fixedly disposed in the cavity to support the test tube containing the specimen; an extraction device, used for placing the test tube onto the support and removing the test tube from the support; In which, the box wall forms an opening to the internal space of the cavity; a sealing cover is fixedly provided on the storage box to completely cover the cavity; the support member forms a plurality of positioning grooves corresponding to the test tubes; the extraction device includes: an extraction tube and a conveyor belt; the extraction tube has a conveyor channel to guide the test tube to approach / move away from the support member along the first direction formed by the conveyor channel; the extraction tube forms an extraction port entering the interior of the conveyor channel, and the extraction port has an end cover to seal the conveyor channel; the conveyor belt is arranged in the conveyor channel to provide power for the movement of the test tube.

2. The biological tissue sample storage box according to claim 1, characterized in that: The extraction device further comprises: a loading member, disposed in the positioning groove to clamp the test tube; A magnetic block is fixedly arranged on one end of the loading member close to the extraction tube; A first electromagnet is fixedly mounted on the support member and located on the extraction tube; Wherein, the inner wall of the positioning groove forms a guide groove for guiding the loading part to approach or move away from the extraction pipe.

3. The biological tissue sample storage box according to claim 2, characterized in that: An elastic member is provided between the loading member and the inner wall of the positioning groove; The elastic member always applies a pulling force to the loading member away from the extraction tube.

4. The biological tissue sample storage box according to claim 1, characterized in that: A pulley in contact with the surface of the support member is provided at the bottom of the extraction pipe; The pulley is connected to the bottom of the extraction pipe via an elastic plate.

5. The biological tissue sample storage box according to claim 4, characterized in that: There are a plurality of positioning grooves, which are arranged in a circular pattern on the surface of the support member; A slide rail is formed on the surface of the support member, and the slide rail is used to guide the pulley to move along the distribution track of the positioning groove.

6. The biological tissue sample storage box according to claim 1, characterized in that: There are at least two transmission belts, which are arranged opposite to each other in the transmission channel along the radial direction of the transmission channel; A power wheel is rotatably arranged in the transmission channel, and the transmission belt is sleeved on the power wheel to enable the transmission belt to rotate; Among them, one transmission belt corresponds to two power wheels, and the two power wheels are distributed up and down along the first direction.

7. The biological tissue sample storage box according to any one of claim 6, characterized in that: The power wheel close to the positioning groove can reciprocate along the radial direction of the transmission channel; Among them, the inner wall of the transmission channel forms a movable groove for the power wheel close to the positioning groove to move; a slider is movably set in the movable groove, and the slider is rotationally connected to the power wheel; the slider is connected to the inner wall of the movable groove by a first elastic member.

8. The biological tissue sample storage box according to claim 7, characterized in that: A rotating plate is provided on the sealing cover; An extraction port corresponding to the extraction tube is formed on the rotating plate.

9. The biological tissue sample storage box according to claim 1, characterized in that: The support plate is connected to the inner wall of the cavity via a buffer assembly, and the buffer assembly includes: a support ring, disposed on the inner wall of the cavity; a connecting member, used for connecting the support ring and the support member; A shock absorber is arranged on the inner wall of the cavity to support the support ring.

10. The biological tissue sample storage box according to claim 1, characterized in that: It also includes a temperature and humidity controller, which is electrically connected to the central controller to control the temperature and humidity in the cavity.

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