Hepatitis C detection kit

Abstract

The utility model relates to a hepatitis C detection kit. The sampling part and the detection part are located in the box body, the sampling part comprises a capillary tube with oblique notches at the two ends, one end of the capillary tube can collect a detection sample, the other end of the capillary tube is inserted into a detection chamber with a vacuum cavity inside after collection is completed, and the detection sample is detected through detection test paper located in the detection chamber. According to the utility model, through the integrated design of collection and detection and the combination of the collection part and the detection part in the box body, the technical problem that the risk of leakage of samples carrying hepatitis C viruses is increased due to multiple steps and independent operation in the traditional hepatitis C detection process is solved.

Description

Technical Field

[0001] The utility model relates to the field of medical devices, and more specifically to a hepatitis C detection kit. Background Art

[0002] In the prior art, hepatitis C test kits are used to quickly detect hepatitis C virus;

[0003] Traditional hepatitis C test kits require manual sampling, followed by amplification and other processing before testing with a test strip;

[0004] However, during use, the cumbersome operating steps and independent operations increase the risk of hepatitis C virus leakage.

[0005] Therefore, how to provide a new hepatitis C detection kit in which sampling, amplification and detection are all located in a closed space to reduce the risk of hepatitis C virus leakage is a problem that needs to be urgently solved by those skilled in the art. Utility Model Content

[0006] In view of this, the present invention provides a hepatitis C detection kit, which aims to solve the technical problem that the hepatitis C detection process has many steps and all are operated independently, which increases the risk of leakage of samples carrying hepatitis C virus.

[0007] A hepatitis C detection kit, comprising:

[0008] A box body, the box body having a first end face and a second end face arranged opposite to each other along a length direction thereof, the first end face being provided with a sampling port;

[0009] The sampling part includes a driving part and a capillary tube and a transmission frame located inside the box body and arranged on one side corresponding to the sampling port. The driving part is installed on the outside of the box body. The capillary tube is arranged along the length direction of the box body and has oblique cuts at both ends. The transmission frame is slidably connected to the box body along the length direction thereof. The transmission output end of the transmission frame is located inside the box body and is tightly connected to the capillary tube. A strip-shaped avoidance hole is opened on the box body. The transmission input end of the transmission frame passes through the strip-shaped avoidance hole and is transmission-connected to the output end of the driving part to drive the capillary tube to move along the length direction of the box body.

[0010] The detection part is arranged inside the box body and located on the side of the sampling part away from the sampling port. The detection input end of the detection part is arranged corresponding to the capillary tube. The detection test paper is arranged inside the detection part and it is a vacuum chamber.

[0011] Through the above technical solution, the utility model solves the technical problem that the traditional hepatitis C detection process has many steps and all are independently operated, which increases the risk of hepatitis C virus leakage during the switching of operation steps. The two ends of the capillary are set with oblique cuts and are movable along the length direction of the box body, so that the capillary automatically collects the sample to be tested by capillary action, and then a tip of the capillary enters the interior of the detection part through the detection input end. Combined with the fact that the interior of the detection part is a vacuum chamber, the sample to be tested in the capillary is automatically sucked into the interior of the detection part and tested by the test paper. It has the characteristics of high automation and high airtightness of the detection process.

[0012] Preferably, the detection part includes an amplification chamber and a detection chamber which are arranged in sequence in the inner cavity of the box body near the second end face, the amplification chamber is arranged near the sampling part, the amplification chamber and the detection chamber are separated by a partition plate, the inner cavity of the amplification chamber is a vacuum chamber and is filled with amplification reagent, the detection input end of the detection part is arranged on the wall of the amplification chamber and can be in contact and connected with the end of the capillary, a liquid hole is provided on the partition plate to connect the amplification chamber and the detection chamber, and the interior of the detection chamber is arranged with a detection test paper and is a vacuum chamber.

[0013] Preferably, the liquid passage hole corresponding to a side port of the amplification chamber is blocked by a film.

[0014] Preferably, the detection chamber further comprises a liquid guide plate, which is firmly connected to the inner wall surface of the detection chamber and whose plate surface is arranged parallel to the partition plate, and the area between the liquid guide plate and the partition plate corresponds to the dripping area of ​​the test paper.

[0015] Preferably, a transparent monitoring window is arranged on the wall of the detection chamber opposite to the detection test paper.

[0016] Preferably, the detection input end is a rubber sealing plug, a penetrating mounting hole is opened on one side wall of the amplification chamber corresponding to the capillary tube, and the rubber sealing plug is installed in the mounting hole.

[0017] Preferably, the rubber sealing plug is provided with a recess on one end surface corresponding to the capillary tube for facilitating the insertion of the capillary tube.

[0018] Preferably, it further comprises a guide frame, which is fastened to the interior of the box body and located between the sampling port and the amplification chamber. The guide frame is provided with a guide groove along the length direction of the box body, and the transmission frame is slidably connected to the guide groove.

[0019] Preferably, the transmission frame includes a transmission tube and a connecting plate, the outer cylindrical surface of the transmission tube is slidably connected to the guide groove, and the inner cylindrical surface thereof is coaxially arranged with the capillary and is tightly connected thereto, the first end of the connecting plate is tightly connected to the transmission tube, and the second end of the connecting plate passes through the strip avoidance hole and is located outside the box body, the driving part is a push plate and is arranged along the length direction of the box body, and the push plate is tightly connected to the second end of the connecting plate.

[0020] Preferably, the push plate has a rough driving surface.

[0021] It can be seen from the above technical solutions that, compared with the prior art, the present invention discloses a hepatitis C detection kit having the following beneficial effects:

[0022] 1. After the capillary tube collects the test sample at one end, the other end can be inserted into the test chamber for testing. The collection and testing are integrated and completed inside the box, reducing the risk of hepatitis C virus leakage;

[0023] 2. Before entering the testing room, the test sample must pass through the amplification chamber to amplify the amount of hepatitis C virus in the amplification chamber to improve the accuracy of the test results;

[0024] 3. The liquid passage between the detection chamber and the amplification chamber is blocked by a thin film to prevent the reagents in the amplification chamber from contaminating the test strip before use;

[0025] 4. Both the detection chamber and the amplification chamber are vacuum chambers. After the amplification chamber is connected to the outside world through a capillary tube, the pressure difference between the amplification chamber and the detection chamber will cause the membrane to break, thereby opening the liquid hole, which has the characteristics of a high degree of automation.

[0026] 5. The liquid guide plate located in the test chamber guides the sample to be tested into the test chamber so that it drips accurately into the dripping area of ​​the test paper, thereby improving the accuracy of the test results;

[0027] 6. A recess is provided on one end face of the rubber sealing plug corresponding to the capillary tube to facilitate the insertion of the capillary tube, thereby reducing the resistance to the insertion of the capillary tube. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 This is a three-dimensional schematic diagram of a hepatitis C detection kit provided by the utility model;

[0029] Figure 2 A top view of a hepatitis C detection kit provided by the utility model;

[0030] Figure 3 for Figure 2 AA section view;

[0031] Figure 4 This is a partial cross-sectional view of a hepatitis C detection kit provided by the utility model.

[0032] Among them: 1-box body; 2-sampling part; 11-sampling port; 21-capillary; 22-transmission frame; 23-guide frame; 31-test paper; 32-amplification chamber; 33-detection chamber; 34-partition plate; 35-liquid hole; 36-film; 37-rubber sealing plug; 221-transmission tube; 222-connecting plate; 223-push plate; 331-liquid guide plate; 332-monitoring window. DETAILED DESCRIPTION

[0033] The principles and features of the present invention are described below in conjunction with the accompanying drawings. The examples given are only used to explain the present invention and are not used to limit the scope of the present invention.

[0034] It should be noted that the process of hepatitis C virus amplification and the detection principle of the test strip are not described in this embodiment. The amplification and detection principles can be referred to the invention patent with publication number CN112501357A;

[0035] See attached Figure 1-4 , the embodiment of the utility model discloses a hepatitis C detection kit, comprising: a box body 1, a sampling part 2 and a detection part;

[0036] The box body 1 has a first end face and a second end face arranged opposite to each other along its length direction, and the first end face is provided with a sampling port 11;

[0037] The sampling unit 2 includes a driving unit and a capillary tube 21 and a transmission frame 22 located inside the box body 1 and arranged on one side of the sampling port 11. The driving unit is mounted on the outside of the box body 1. The capillary tube 21 is arranged along the length of the box body 1 and has oblique cuts at both ends. The transmission frame 22 is slidably connected to the box body 1 along its length. The transmission output end of the transmission frame 22 is located inside the box body 1 and is tightly connected to the capillary tube 21. A strip-shaped avoidance hole is opened on the box body. The transmission input end of the transmission frame 22 passes through the strip-shaped avoidance hole and is transmission-connected to the output end of the driving unit to drive the capillary tube 21 to move along the length of the box body 1.

[0038] The detection unit is arranged inside the box body 1 and located on the side of the sampling unit 2 away from the sampling port. The detection input end of the detection unit is arranged corresponding to the capillary 21. The detection test paper 31 is arranged inside the detection unit and it is a vacuum chamber.

[0039] Specifically, one end of the capillary tube 21 can leak out of the box body 1 through the sampling port 11 .

[0040] In order to further optimize the above technical solution, the detection part includes an amplification chamber 32 and a detection chamber 33 which are arranged in sequence in the inner cavity of the box body 1 near the second end face. The amplification chamber 32 is arranged close to the sampling part 2. The amplification chamber 32 and the detection chamber 33 are separated by a partition plate 34. The inner cavity of the amplification chamber 32 is a vacuum chamber and is filled with amplification reagent. The detection input end of the detection part is arranged on the wall of the amplification chamber 32 and can be in contact and communication with the end of the capillary 21. A liquid hole 35 is provided on the partition plate 34 to connect the amplification chamber 32 and the detection chamber 33. The interior of the detection chamber 33 is arranged with a test paper 31 and is a vacuum chamber.

[0041] In order to further optimize the above technical solution, the liquid passage hole 35 corresponding to a side port of the amplification chamber 32 is blocked by a film 36 .

[0042] Specifically, the liquid passage hole 35 is located at an upper middle portion of the partition plate 34 in a direction away from the test paper 31 .

[0043] More specifically, after the amplification reagent is mixed with the test sample, the liquid level will not exceed the liquid hole 35 when placed horizontally.

[0044] In order to further optimize the above technical solution, the detection chamber 33 also includes a liquid guide plate 331, which is tightly connected to the inner wall of the detection chamber 33 and its plate surface is arranged parallel to the partition plate 34. The area between the liquid guide plate 331 and the partition plate 34 corresponds to the dripping area of ​​the test paper 31.

[0045] In order to further optimize the above technical solution, a transparent monitoring window 332 is arranged on the wall of the detection chamber 33 opposite to the detection test paper 31.

[0046] In order to further optimize the above technical solution, the detection input end is a rubber sealing plug 37, and a penetrating mounting hole is opened on one side wall of the amplification chamber 32 corresponding to the capillary 21, and the rubber sealing plug 37 is installed in the mounting hole.

[0047] In order to further optimize the above technical solution, a recess is provided on one end surface of the rubber sealing plug 37 corresponding to the capillary 21 to facilitate the insertion of the capillary.

[0048] Specifically, the pit is arranged corresponding to the axis of the capillary 21 .

[0049] In order to further optimize the above technical solution, a guide frame 23 is also included. The guide frame 23 is fastened to the inside of the box body 1 and is located between the sampling port 11 and the amplification chamber 32. The guide frame 23 has a guide groove along the length direction of the box body 1, and the transmission frame 22 is slidably connected to the guide groove.

[0050] In order to further optimize the above technical solution, the transmission frame 22 includes a transmission tube 221 and a connecting plate 222. The outer cylindrical surface of the transmission tube 221 is slidably connected to the guide groove, and its inner cylindrical surface is coaxially arranged with the capillary 21 and is tightly connected thereto. The first end of the connecting plate 222 is tightly connected to the transmission tube 221, and the second end of the connecting plate 222 passes through the strip avoidance hole and is located outside the box body 1. The driving part is a push plate 223 and is arranged along the length direction of the box body 1. The push plate 223 is tightly connected to the second end of the connecting plate 222.

[0051] In order to further optimize the above technical solution, the surface of the pushing plate 223 is provided with a rough driving surface.

[0052] The specific principles and usage of a hepatitis C detection kit provided in this embodiment are as follows:

[0053] 1. Manually push the push plate 223 toward the sampling port 11, and one end of the capillary tube 21 leaks out of the sampling port 11;

[0054] 2. Sampling the test sample through the capillary action of the capillary tube 21 itself;

[0055] 3. After sampling, place the HCV test kit horizontally and manually push the push plate 223 away from the sampling port 11 until the other end of the capillary tube 21 penetrates the rubber seal 37 and is located in the amplification chamber 32. The test sample in the capillary tube 21 enters the amplification chamber 32 under the influence of air pressure, mixes with the amplification reagent, and then stands for 10 minutes.

[0056] 4. When the rubber seal 37 is pierced, the film 36 ruptures, and the liquid hole 35 opens. After the test kit is left standing, hold it upright with the sampling port 11 facing upward. The amplified HCV test mixed solution enters the test chamber 33 through the liquid hole 35 and, guided by the liquid guide plate 331, drips onto the dripping area of ​​the test paper 31.

[0057] 5. Observe the test results of the test paper 31 through the monitoring window 332.

[0058] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A hepatitis C detection kit, characterized in that: include: A box body (1), the box body (1) having a first end face and a second end face arranged opposite to each other along its length direction, the first end face being provided with a sampling port (11); The sampling part (2) comprises a driving part, a capillary tube (21) and a transmission frame (22) located inside the box body (1) and arranged on one side of the sampling port (11); the driving part is installed outside the box body (1); the capillary tube (21) is arranged along the length direction of the box body (1) and has oblique cuts at both ends; the transmission frame (22) is slidably connected to the box body (1) along the length direction thereof; the transmission output end of the transmission frame (22) is located inside the box body (1) and is tightly connected to the capillary tube (21); a strip-shaped avoidance hole is opened on the box body; the transmission input end of the transmission frame (22) passes through the strip-shaped avoidance hole and is transmission-connected to the output end of the driving part to drive the capillary tube (21) to move along the length direction of the box body (1); The detection part is arranged inside the box body (1) and is located on a side of the sampling part (2) away from the sampling port. The detection input end of the detection part is arranged corresponding to the capillary tube (21). A detection test paper (31) is arranged inside the detection part and the detection chamber is a vacuum chamber.

2. A hepatitis C detection kit according to claim 1, characterized in that: The detection portion comprises an amplification chamber (32) and a detection chamber (33) which are sequentially arranged in the inner cavity of the box body (1) near the second end face, the amplification chamber (32) being arranged near the sampling portion (2), the amplification chamber (32) and the detection chamber (33) being separated by a partition plate (34), the inner cavity of the amplification chamber (32) being a vacuum chamber and being filled with an amplification reagent, the detection input end of the detection portion being arranged on the wall surface of the amplification chamber (32) and being in contact and communication with the end of the capillary (21), the partition plate (34) being provided with a liquid hole (35) connecting the amplification chamber (32) and the detection chamber (33), the interior of the detection chamber (33) being provided with a detection test paper (31) and being a vacuum chamber.

3. A hepatitis C detection kit according to claim 2, characterized in that: The liquid passage hole (35) is blocked by a film (36) at a side port corresponding to the amplification chamber (32).

4. A hepatitis C detection kit according to claim 3, characterized in that: The detection chamber (33) further comprises a liquid guide plate (331), wherein the liquid guide plate (331) is firmly connected to the inner wall surface of the detection chamber (33) and its plate surface is arranged parallel to the plate surface of the partition plate (34), and the area between the liquid guide plate (331) and the partition plate (34) corresponds to the dripping area of ​​the detection test paper (31).

5. A hepatitis C detection kit according to claim 3, characterized in that: A transparent monitoring window (332) is arranged on the wall of the detection chamber (33) opposite to the detection test paper (31).

6. A hepatitis C detection kit according to claim 2, characterized in that: The detection input end is a rubber sealing plug (37), and a through mounting hole is provided on a side wall of the amplification chamber (32) corresponding to the capillary tube (21), and the rubber sealing plug (37) is installed in the mounting hole.

7. A hepatitis C detection kit according to claim 6, characterized in that: The rubber sealing plug (37) is provided with a recess on one end surface corresponding to the capillary tube (21) for facilitating the insertion of the capillary tube.

8. A hepatitis C detection kit according to claim 2, characterized in that: The invention also includes a guide frame (23), which is fastened to the interior of the box body (1) and is located between the sampling port (11) and the amplification chamber (32). The guide frame (23) is provided with a guide groove along the length direction of the box body (1), and the transmission frame (22) is slidably connected to the guide groove.

9. A hepatitis C detection kit according to claim 8, characterized in that: The transmission frame (22) comprises a transmission tube (221) and a connecting plate (222); the outer cylindrical surface of the transmission tube (221) is slidably connected to the guide groove, and the inner cylindrical surface of the transmission tube (221) is coaxially arranged with the capillary tube (21) and is tightly connected thereto; the first end of the connecting plate (222) is tightly connected to the transmission tube (221); the second end of the connecting plate (222) passes through the strip-shaped avoidance hole and is located outside the box body (1); the driving part is a pushing plate (223) and is arranged along the length direction of the box body (1); the pushing plate (223) is tightly connected to the second end of the connecting plate (222).

10. A hepatitis C detection kit according to claim 9, characterized in that: The push plate (223) is provided with a rough driving surface on its surface.

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