An agarose gel cutting knife

Abstract

This utility model relates to the field of agarose gel technology, specifically to an agarose gel cutting tool, including a mold. The surface of the mold is provided with graduations and an adjustment structure. The adjustment structure includes a handle, a worm gear fixedly connected to the surface of the handle, and a worm wheel engaged with the surface of the worm gear. Two sets of moving blocks are slidably connected to both sides of the mold. A pointer is fixedly connected to the bottom of the set of moving blocks near the threaded rod. A locking structure is provided within the set of moving blocks near the threaded rod. A rotating structure is provided between the two sets of moving blocks. This utility model features graduations and an adjustment structure, which can drive the cutting tool to move and precisely adjust its position. The locking and rotating structures allow switching between hole-making and cutting to achieve different effects, and facilitate the rotation adjustment of the rotating blocks.

Description

Technical Field

[0001] This utility model belongs to the field of agarose gel technology, specifically relating to an agarose gel cutting tool. Background Technology

[0002] Gel electrophoresis is widely used in the biotechnology field to separate biomolecules from target organisms. When separating biomolecules from a gel, especially when recovering target DNA bands, it is usually necessary to cut the gel to obtain the target biomolecules for subsequent analysis. During gel electrophoresis, macromolecules migrate and form bands. The migration distance of each band during electrophoresis is determined by the size, type, and charge of the biomolecules within the band. Cutting the gel along the bands yields the desired gel.

[0003] In existing technologies, agarose gel is often cut manually, which requires the operator to hold the tool, making it difficult to guarantee cutting accuracy and cumbersome to operate. To address this, we propose an agarose gel cutting tool. Utility Model Content

[0004] In order to overcome the above-mentioned technical problems, the purpose of this utility model is to provide an agarose gel cutting knife, so as to solve the problem mentioned in the background art that the existing technology often cuts agarose gel manually, which requires the operator to hold the knife, which cannot guarantee the cutting accuracy and is also more troublesome to operate.

[0005] To achieve the above objectives, this utility model provides the following technical solution: an agarose gel cutter, comprising a mold, the surface of which is provided with graduations, four sets of fixing blocks fixedly connected to both sides of the mold, an adjustment structure provided on the surface of the mold, the adjustment structure including a handle, a worm gear fixedly connected to the surface of the handle, a worm wheel meshing with the surface of the worm gear, a threaded rod fixedly connected inside the worm wheel, two sets of moving blocks slidably connected to both sides of the mold, a fixed rod slidably connected to the bottom of the set of moving blocks away from the threaded rod, a pointer fixedly connected to the bottom of the set of moving blocks closer to the threaded rod, and a locking structure provided inside the set of moving blocks closer to the threaded rod. The structure includes a second handle, a connecting rod fixedly connected to the surface of the second handle, a fixed plate fixedly connected to the surface of the connecting rod, a spring sleeved on the surface of the connecting rod, and a locking block fixedly connected to the surface of the fixed plate. A rotating structure is provided between the two sets of moving blocks. The rotating structure includes a rotating block, with insert rods fixedly connected to both ends of the rotating block. Two sets of sliding grooves are symmetrically opened vertically inside the rotating block. Two sets of springs are symmetrically fixedly connected inside the two sets of sliding grooves. Two sets of sliders are symmetrically slidably connected inside the two sets of sliding grooves. A pull rod is fixedly connected to the surface of each set of sliders. A sample comb tooth is fixedly connected to the surface of one set of sliders, and a cutter is fixedly connected to the surface of the other set of sliders.

[0006] Preferably, the two ends of the threaded rod are rotatably connected to two sets of fixed blocks on one side of the mold, and the two ends of the fixed rod are fixedly connected to two sets of fixed blocks on the other side of the mold. The pointer and the scale are set on the same side of the mold.

[0007] Preferably, a set of the movable blocks has a second sliding groove inside, the fixed plate is slidably connected in the second sliding groove, the connecting rod passes through one side of the second sliding groove and is fixedly connected to the fixed plate, and the two ends of the first spring are fixedly connected to the surface of the fixed plate and the inner wall of the second sliding groove, respectively.

[0008] Preferably, the insert rods on both sides of the rotating block are rotatably connected to the interior of the two sets of moving blocks, and a square groove is opened on the surface of the set of insert rods near the locking block, and the locking block is inserted into the square groove.

[0009] Preferably, the sample comb teeth and the cutter pass through the top and bottom of the first slide groove and are fixedly connected to the two sets of sliders, respectively, and the two ends of the second spring are fixedly connected to the inner wall of the first slide groove and the surface of the slider, respectively.

[0010] Preferably, the surface of the rotating block is provided with a sliding groove three, the pull rod is C-shaped, and the two ends of the pull rod are fixedly connected to the surface of the slider through the sliding groove three.

[0011] Preferably, the sample comb teeth and the cutter are arranged alternately.

[0012] Compared with the prior art, the beneficial effects of this utility model are:

[0013] 1. This agarose gel cutting tool is equipped with a scale and adjustment structure. By rotating the handle, the worm gear is rotated, and the worm gear meshes with the worm wheel, causing the worm wheel to drive the threaded rod to rotate. This, in turn, causes the moving block to move with the rotation of the threaded rod, thereby moving the cutting tool and adjusting its position. The pointer at the bottom of the moving block works in conjunction with the scale to precisely adjust the position of the cutting tool. The self-locking property of the worm wheel and worm gear reduces the possibility of the cutting tool being affected by external forces.

[0014] 2. This agarose gel cutting tool is equipped with a locking structure and a rotating structure. Pulling the handle two moves the fixed plate through the connecting rod. At this time, the spring one is compressed, causing the locking block to move out of the square groove of the insertion rod on one side, releasing the rotation restriction on the rotating block. This allows the rotating block to be rotated and adjusted. With the sample comb teeth and cutter set at the top and bottom of the rotating block, it can switch between hole forming and cutting to achieve different effects. At the same time, pulling the pull rod can drive the sample comb teeth or cutter to move into the rotating block through the slider, which facilitates the rotation adjustment of the rotating block. Attached Figure Description

[0015] Figure 1 This is a three-dimensional structural schematic diagram of the present invention;

[0016] Figure 2 This is a schematic diagram of the structure of this utility model in dynamic form;

[0017] Figure 3 This is an exploded view of the adjusting structure of this utility model;

[0018] Figure 4 This is an exploded view of the moving block, engaging structure, and rotating block of this utility model;

[0019] Figure 5 This is a cross-sectional view of the rotating structure of this utility model.

[0020] In the diagram: 1. Mold; 11. Scale; 12. Fixing block; 2. Adjustment structure; 21. Handle 1; 22. Worm gear; 23. Worm wheel; 24. Threaded rod; 25. Moving block; 26. Fixing rod; 27. Pointer; 3. Engaging structure; 31. Handle 2; 32. Connecting rod; 33. Fixing plate; 34. Spring 1; 35. Locking block; 4. Rotating structure; 41. Rotating block; 42. Insert rod; 43. Slide 1; 44. Spring 2; 45. Slider; 46. Pull rod; 47. Sample comb teeth; 48. Cutter. Detailed Implementation

[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0022] Please see Figure 1-5 One embodiment provided by this utility model:

[0023] An agarose gel cutter includes a mold 1 with graduations 11 on its surface. Four sets of fixing blocks 12 are fixedly connected to both sides of the mold 1. An adjustment structure 2 is provided on the surface of the mold 1, including a handle 21. A worm gear 22 is fixedly connected to the surface of the handle 21, and a worm wheel 23 meshes with the surface of the worm gear 22. A threaded rod 24 is fixedly connected inside the worm wheel 23. Two sets of moving blocks 25 are slidably connected to both sides of the mold 1. A fixed rod 26 is slidably connected to the bottom of the moving block 25 away from the threaded rod 24, and a pointer 27 is fixedly connected to the bottom of the moving block 25 near the threaded rod 24. An engaging structure 3 is provided inside, including a handle 31. A connecting rod 32 is fixedly connected to the surface of the handle 31, and a fixing plate 33 is fixedly connected to the surface of the connecting rod 32. A spring 34 is sleeved on the surface of the connecting rod 32, and a locking block 35 is fixedly connected to the surface of the fixing plate 33. A rotating structure 4 is provided between the two sets of moving blocks 25. The rotating structure 4 includes a rotating block 41, with insert rods 42 fixedly connected to both ends of the rotating block 41. Two sets of sliding grooves 43 are symmetrically opened on the inside of the rotating block 41. Two sets of springs 44 are symmetrically fixedly connected inside the two sets of sliding grooves 43, and two sets of sliders 45 are symmetrically slidably connected inside the two sets of sliding grooves 43. Each set of sliders 45 has a pull rod 46 fixedly connected to its surface. One set of sliders 45 has sample comb teeth 47 fixedly connected to its surface, and another set of sliders 45 has a cutter 48 fixedly connected to its surface. A scale 11 and an adjustment structure 2 are provided. By rotating the handle 21, the worm 22 rotates, meshing with the worm wheel 23. The worm wheel 23 then drives the threaded rod 24 to rotate, which in turn moves the moving block 25 along with the rotation of the threaded rod 24. This allows the cutter to move and its position to be adjusted. The pointer 27 at the bottom of the moving block 25 engages with the scale 11, allowing for precise adjustment of the cutter's position. The worm wheel 23 and worm 22... To reduce the possibility of the cutting blade being affected by external forces, a locking structure 3 and a rotating structure 4 are set up. Pulling the handle 31 moves the fixing plate 33 through the connecting rod 32. At this time, the spring 34 is compressed, causing the locking block 35 to move out of the square groove of the insertion rod 42 on one side, releasing the rotation restriction on the rotating block 41. This allows the rotating block 41 to be rotated and adjusted. With the sample comb teeth 47 and the cutter 48 set at the top and bottom of the rotating block 41, it is possible to switch between hole forming and cutting to achieve different effects. At the same time, pulling the pull rod 46 can move the sample comb teeth 47 or the cutter 48 into the rotating block 41 through the slider 45, which facilitates the rotation adjustment of the rotating block 41.

[0024] Furthermore, the two ends of the threaded rod 24 are rotatably connected to two sets of fixed blocks 12 on one side of the mold 1, and the two ends of the fixed rod 26 are fixedly connected to two sets of fixed blocks 12 on the other side of the mold 1. The pointer 27 and the scale 11 are set on the same side of the mold 1. By cooperating with the pointer 27 and the scale 11, the position of the cutting blade can be precisely adjusted. By rotating the handle 21, the worm 22 is driven to rotate. The worm 22 meshes with the worm wheel 23, causing the worm wheel 23 to drive the threaded rod 24 to rotate. This, in turn, causes a set of moving blocks 25 to move with the rotation of the threaded rod 24. The fixed rod 26 limits the rotation of the rotating structure 4 through the other set of moving blocks 25, preventing the moving blocks 25 and the rotating structure 4 from rotating with the threaded rod 24.

[0025] Furthermore, a set of movable blocks 25 has a sliding groove 2 inside, and a fixed plate 33 is slidably connected in the sliding groove 2. A connecting rod 32 passes through one side of the sliding groove 2 and is fixedly connected to the fixed plate 33. The two ends of the spring 34 are fixedly connected to the surface of the fixed plate 33 and the inner wall of the sliding groove 2, respectively. When there is no external force, the fixed plate 33 abuts against the surface of the insertion rod 42 on one side through the spring 34. At the same time, the spring 34 will not interfere with the connecting rod 32 when it deforms.

[0026] Furthermore, the insert rods 42 on both sides of the rotating block 41 are rotatably connected to the interior of the two sets of moving blocks 25. A square groove is opened on the surface of the set of insert rods 42 near the locking block 35. The locking block 35 is inserted into the square groove. When there is no external force, the fixing plate 33 is abutted against the surface of the insert rod 42 on one side by the spring 34. At this time, the locking block 35 is inserted into the square groove, thereby preventing the rotation of the rotating block 41. After pulling the handle 31 to move the locking block 35 out of the square groove, the rotating block 41 can be rotated and adjusted. Since the cross-section of the locking block 35 is square, the minimum adjustment angle of the rotating block 41 is ninety degrees.

[0027] Furthermore, the sample comb teeth 47 and the cutter 48 pass through the top and bottom of the slide groove 43 respectively and are fixedly connected to the two sets of sliders 45. The two ends of the spring 44 are fixedly connected to the inner wall of the slide groove 43 and the surface of the slider 45 respectively. When there is no external force, the spring 44 pushes the slider 45 to the upper and lower ends, so that the sample comb teeth 47 and the cutter 48 are pushed outward from the top and bottom of the rotating block 41. At this time, regardless of whether the sample comb teeth 47 or the cutter 48 is at the bottom, their surfaces can contact the surface of the mold 1.

[0028] Furthermore, the surface of the rotating block 41 is provided with a sliding groove three, and the pull rod 46 is C-shaped. The two ends of the pull rod 46 are fixedly connected to the surface of the slider 45 through the sliding groove three. Pulling the pull rod 46 can drive the sample comb 47 or the cutter 48 to move into the rotating block 41 through the slider 45, which facilitates the rotation adjustment of the rotating block 41.

[0029] Furthermore, the sample comb teeth 47 and the cutter 48 are arranged alternately. After the agarose solution is poured into the mold 1, the sample comb teeth 47 are inserted into the agarose solution. After the agarose solution solidifies, the sample comb teeth 47 are removed. Sample holes are formed on the surface of the agarose gel. The strips corresponding to the required sample holes can be cut off by the cutter 48, which is arranged alternately with the sample comb teeth 47.

[0030] Working principle: In use, the agarose solution is poured into mold 1. By turning handle 21, the worm 22 is rotated, and the worm 22 meshes with the worm wheel 23, causing the worm wheel 23 to drive the threaded rod 24 to rotate. This, in turn, causes the moving block 25 to move with the rotation of the threaded rod 24, thereby moving the sample comb teeth 47. The position of the sample comb teeth 47 is precisely adjusted by the pointer 27 at the bottom of the moving block 25 in conjunction with the scale 11. The sample comb teeth 47 are inserted into the agarose solution. After the agarose solution solidifies, pulling the lever 46 will move the sample comb teeth 47 and the cutter 48 towards the rotating block 45 via the slider 45. 1. Move the sample comb 47 from the surface of the agarose gel. At this time, a sample well is formed on the surface of the agarose gel. Pull the handle 31 to move the fixing plate 33 through the connecting rod 32. At this time, the spring 34 is compressed, causing the locking block 35 to move out of the square groove of the side insertion rod 42, releasing the rotation restriction on the rotating block 41. Adjust the rotating block 41 to a horizontal state, and electrophoresis experiments can be performed in the sample well. Pull the handle 31 to release the rotation restriction on the rotating block 41. Rotate the rotating block 41 to make the cutter 48 lower. Move the cutter 48 by rotating the handle 21, and then cut the agarose gel.

[0031] It will be apparent to those skilled in the art that this invention is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this invention. Therefore, the embodiments should be considered illustrative and non-limiting in all respects, and the scope of this invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

Claims

1. An agarose gel cutting knife comprising a mould (1), characterised in that: The surface of the mold (1) is provided with a scale (11). Four sets of fixing blocks (12) are fixedly connected to both sides of the mold (1). The surface of the mold (1) is provided with an adjustment structure (2). The adjustment structure (2) includes a handle (21). A worm gear (22) is fixedly connected to the surface of the handle (21). A worm wheel (23) meshes with the surface of the worm gear (22). A threaded rod (24) is fixedly connected inside the worm wheel (23). Two sets of moving blocks (25) are slidably connected to both sides of the mold (1). A fixed rod (26) is slidably connected to the bottom of the set of moving blocks (25) away from the threaded rod (24). A pointer (27) is fixedly connected to the bottom of the set of moving blocks (25) close to the threaded rod (24). A locking structure (3) is provided inside the set of moving blocks (25) close to the threaded rod (24). The locking structure (3) includes a handle (31). The surface of the handle (31) A connecting rod (32) is fixedly connected, and a fixing plate (33) is fixedly connected to the surface of the connecting rod (32). A spring (34) is sleeved on the surface of the connecting rod (32), and a locking block (35) is fixedly connected to the surface of the fixing plate (33). A rotating structure (4) is provided between the two sets of moving blocks (25). The rotating structure (4) includes a rotating block (41). Insert rods (42) are fixedly connected to both ends of the rotating block (41). Two sets of sliding grooves (43) are symmetrically opened inside the rotating block (41). Two sets of springs (44) are symmetrically fixedly connected inside the two sets of sliding grooves (43). Two sets of sliders (45) are symmetrically slidably connected inside the two sets of sliding grooves (43). Pull rods (46) are fixedly connected to the surface of both sets of sliders (45). Sample comb teeth (47) are fixedly connected to the surface of one set of sliders (45), and a cutter (48) is fixedly connected to the surface of the other set of sliders (45).

2. The agarose gel cutting tool according to claim 1, characterized in that: The two ends of the threaded rod (24) are rotatably connected to the two sets of fixed blocks (12) on one side of the mold (1), and the two ends of the fixed rod (26) are fixedly connected to the two sets of fixed blocks (12) on the other side of the mold (1). The pointer (27) and the scale (11) are set on the same side of the mold (1).

3. The agarose gel cutting tool according to claim 1, characterized in that: A set of movable blocks (25) has a sliding groove two inside, the fixed plate (33) is slidably connected in the sliding groove two, the connecting rod (32) passes through one side of the sliding groove two and is fixedly connected to the fixed plate (33), and the two ends of the spring (34) are fixedly connected to the surface of the fixed plate (33) and the inner wall of the sliding groove two, respectively.

4. The agarose gel cutting tool according to claim 1, characterized in that: The insert rods (42) on both sides of the rotating block (41) are rotatably connected to the interior of the two sets of moving blocks (25). A square groove is opened on the surface of the set of insert rods (42) near the card block (35), and the card block (35) is inserted into the square groove.

5. The agarose gel cutting tool according to claim 1, characterized in that: The sample comb teeth (47) and the cutter (48) pass through the top and bottom of the first slide groove (43) respectively and are fixedly connected to the two sets of sliders (45). The two ends of the second spring (44) are fixedly connected to the inner wall of the first slide groove (43) and the surface of the slider (45) respectively.

6. The agarose gel cutting tool according to claim 1, characterized in that: The rotating block (41) has a sliding groove three on its surface, and the pull rod (46) is C-shaped. The two ends of the pull rod (46) are fixedly connected to the surface of the slider (45) through the sliding groove three.

7. The agarose gel cutting tool according to claim 1, characterized in that: The sample comb teeth (47) and the cutter (48) are arranged alternately.

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