Drug injection device

Abstract

The present invention discloses a drug injection device, comprising a catheter assembly, an injection head and a handle. The catheter assembly comprises an outer sleeve, a drug administration tube and a filler. The filler is filled inside the outer sleeve. A catheter channel is arranged in the middle of the filler. The drug administration tube is sleeved on the inside of the catheter channel and is slidably connected to the inner wall of the catheter channel. One end of the catheter assembly is connected to the injection head, and the other end is connected to the handle. When injecting drugs into the cerebral ventricle, the drug injection device increases the injection area of ​​the drug, makes the drug diffuse more evenly, is beneficial to the treatment of the patient, and can perform biopsy on the patient's ventricle to obtain samples, which is convenient for medical staff to treat the patient and prevents the patient from suffering pain when biopsy is performed again.

Description

Technical Field

[0001] The invention relates to the technical field of drug injection, in particular to a drug injection device. Background Art

[0002] Intraventricular injection (intracerebroventricular injection) is to inject drugs directly into the ventricles. For chronic experiments, a cannula must be buried in the brain, with the end of the cannula about 1 mm away from the wall of the lateral ventricle and fixed to the skull. During the experiment, the injection tube is passed through the cannula into the lateral ventricle and a trace amount of drug is injected.

[0003] The existing intraventricular injection device has only one injection tube, which results in a smaller area of ​​drug action during drug injection and uneven diffusion effect. The existing injection tube does not have a biopsy sampling function, and after drug injection, an appropriate amount of brain tissue fluid cannot be taken out for testing. To this end, we propose a drug injection device. Summary of the invention

[0004] The object of the present invention is to provide a drug injection device to solve the problems raised in the above background technology.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a drug injection device, comprising a catheter assembly, an injection head and a handle, the catheter assembly comprising an outer sleeve, a drug administration tube and a filler, the filler is filled on the inner side of the outer sleeve, a catheter channel is provided in the middle of the filler, the drug administration tube is sleeved on the inner side of the catheter channel and is slidably connected to the inner wall of the catheter channel, one end of the catheter assembly is connected to the injection head, and the other end is connected to the handle.

[0006] Preferably, the injection head includes a negative pressure chamber, an annular piston, a clamping assembly and a splitting assembly, one end of the outer sleeve is fixed to the negative pressure chamber, one end of the dosing tube passes through the negative pressure chamber and is connected to the input end of the splitting assembly, the splitting assembly is fixed on the negative pressure chamber, the annular piston is located on the inner side of the negative pressure chamber, a sealing ring is fixed on the inner side of the annular piston, the annular piston is interference fit with the outer wall of the dosing tube through the sealing ring, and the annular piston is slidingly fit with the inner wall of the negative pressure chamber, a plurality of collecting holes are provided at equal angles on the outer side of the negative pressure chamber near one end of the outer sleeve, and the clamping assembly is fixed on the annular piston.

[0007] Preferably, the clamping assembly includes a clamping shaft, a first clamping plate, a return spring and a second clamping plate, the first clamping plate is fixed to the side wall of the annular piston, the second clamping plate is located on the side of the first clamping plate away from the middle of the negative pressure chamber, and the second clamping plate is fixed to the first clamping plate through the return spring, the clamping shaft passes through the first clamping plate, the return spring and the second clamping plate in sequence, and the clamping shaft is slidably connected to the first clamping plate and fixedly connected to the second clamping plate, and a groove matching the clamping shaft is provided on the inner wall of the negative pressure chamber.

[0008] Preferably, the splitter assembly includes a storage tube, a shunt chamber and a shunt tube, one end of the storage tube is fixed to the negative pressure chamber, the shunt chamber is sleeved on the inner side of the storage tube and is slidably connected to the inner wall of the storage tube, one end of the drug delivery tube close to the negative pressure chamber is fixed to the shunt chamber and is connected to the interior of the shunt chamber, a plurality of shunt tubes are provided, and a plurality of shunt tubes are fixed at equal angles at one end of the shunt chamber away from the drug delivery tube, a plurality of shunt tubes are respectively connected to the interior of the shunt chamber, and the shunt tube is made of memory alloy, and the end face is flat.

[0009] Preferably, limiting blocks are fixed on the inner sides of both ends of the storage tube.

[0010] Preferably, the handle includes a mounting tube, a support rod, a drive block and a drive assembly, the end of the outer sleeve away from the negative pressure chamber is fixed to the support tube, an opening is provided at a local position on the outside of the support tube, the drive block is located in the middle of the inside of the mounting tube, and the drive block is slidably sleeved on the outside of the support rod, the two ends of the support rod are respectively fixed to the inner wall of the mounting tube, the end of the dosing tube away from the shunt chamber passes through the drive block and the mounting tube, and is fixedly connected to the drive block and slidably connected to the mounting tube, the drive assembly is fixed on the mounting tube, and the output end of the drive assembly is movably connected to the drive block.

[0011] Preferably, the driving assembly includes an annular knob and a supporting tube, the outer side of the driving block is provided with an external thread, the inner side of the annular knob is provided with an internal thread, the annular knob is sleeved on the outer side of the driving block and is threadedly connected to the driving block, the supporting tube is sleeved on the outer side of the driving block, and one end of the supporting tube is fixed to the side wall of the annular knob, and the other end is rotatably connected to the inner wall of the mounting tube through a bearing.

[0012] Preferably, an annular baffle is fixedly sleeved on the outer sides of both ends of the driving block.

[0013] Preferably, a positioning assembly is provided on the outer side of the annular knob, and the positioning assembly includes an arc-shaped rubber block, a first support block, a second support block, an arc-shaped mounting block, a fixed shaft, a connecting shaft, a buffer spring, an extrusion plate and a fixed plate, the first support block and the second support block are symmetrically distributed on the outer side of the annular knob, and the first support block and the second support block are both fixed to the outer wall of the mounting cylinder, one end of the fixed shaft and the connecting shaft are respectively rotatably connected to the two ends of the arc-shaped mounting block through a pin shaft, the end of the fixed shaft away from the arc-shaped mounting block is fixed to the first support plate, the fixing plate is fixed to the end of the connecting shaft away from the arc-shaped mounting block, the buffer spring and the extrusion plate are both sleeved on the outer side of the connecting shaft, the two ends of the buffer spring are respectively fixed to the fixing plate and the extrusion plate, the extrusion plate is slidably connected to the connecting shaft, a through groove is provided at the end of the first support block away from the mounting cylinder, and the arc-shaped rubber block is fixed to the inner side of the arc-shaped mounting block.

[0014] Compared with the prior art, the present invention has the following beneficial effects:

[0015] The present invention increases the injection area of ​​the drug during ventricle drug injection, making the drug diffuse more evenly, which is beneficial to the treatment of patients. Moreover, the ventricle of the patient can be biopsied to obtain samples, which is convenient for medical staff to treat the patient and prevents the patient from suffering pain when biopsy is performed again. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the overall application of the present invention;

[0017] Figure 2 It is a schematic diagram of the overall structure of the present invention;

[0018] Figure 3 This is a schematic diagram of the structure of the injection head of the present invention;

[0019] Figure 4 This is a schematic diagram of the handle structure of the present invention;

[0020] Figure 5 It is a partial cross-sectional view of the injection head of the present invention;

[0021] Figure 6 It is a schematic diagram of the structure of the catheter assembly of the present invention;

[0022] Figure 7 for Figure 4 A magnified image of the middle area;

[0023] Figure 8 for Figure 4 Enlarged view of area B;

[0024] Fig. 9 for Figure 5 Enlarged view of area C.

[0025] In the figure: 1-catheter assembly; 2-outer sleeve; 3-drug delivery tube; 4-filler; 5-catheter channel; 6-injection head; 7-handle; 8-negative pressure chamber; 9-annular piston; 10-clamping assembly; 11-split assembly; 12-sealing ring; 13-collecting hole; 14-clamping shaft; 15-first clamping plate; 16-reset spring; 17-second clamping plate; 18-groove; 19-storage tube; 20-shunt chamber; 21-shunt tube; 2 2-limiting block; 23-mounting cylinder; 24-support rod; 25-driving block; 26-driving assembly; 27-annular knob; 28-support cylinder; 29-annular baffle; 30-positioning assembly; 31-arc rubber block; 32-first support block; 33-second support block; 34-arc mounting block; 35-fixed shaft; 36-connecting shaft; 37-buffer spring; 38-extrusion plate; 39-fixing plate; 40-through groove; 41-opening. DETAILED DESCRIPTION

[0026] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0027] See also Figure 1-9 The present invention provides a technical solution: a drug injection device, comprising a catheter assembly 1, an injection head 6 and a handle 7, wherein the catheter assembly 1 comprises an outer sleeve 2, a drug delivery tube 3 and a filler 4, wherein the filler 4 is filled inside the outer sleeve 2, a catheter channel 5 is provided in the middle of the filler 4, the drug delivery tube 3 is sleeved on the inside of the catheter channel 5 and is slidably connected to the inner wall of the catheter channel 5, one end of the catheter assembly 1 is connected to the injection head 6, and the other end is connected to the handle 7.

[0028] The injection head 6 includes a negative pressure chamber 8, an annular piston 9, a clamping assembly 10 and a splitting assembly 11. One end of the outer sleeve 2 is fixed to the negative pressure chamber 8. One end of the drug delivery tube 3 passes through the negative pressure chamber 8 and is connected to the input end of the splitting assembly 11. The splitting assembly 11 is fixed to the negative pressure chamber 8. The annular piston 9 is located on the inner side of the negative pressure chamber 8. A sealing ring 12 is fixed on the inner side of the annular piston 9. The annular piston 9 has an interference fit with the outer wall of the drug delivery tube 3 through the sealing ring 12, and the annular piston 9 slides with the inner wall of the negative pressure chamber 8. A plurality of collecting holes 13 are provided at equal angles on the outer side of the cavity 8 near one end of the outer sleeve 2. The clamping assembly 10 is fixed on the annular piston 9. After the injection head 6 is inserted into the human body, the friction force between the sealing ring 12 and the drug delivery tube 3 is greater than the friction force between the annular piston 9 and the inner wall of the negative pressure cavity 8. The annular piston 9 can be driven to move in the negative pressure cavity 8 by pushing the drug delivery tube 3. When the annular piston 9 moves inside the negative pressure cavity 8, negative pressure is generated inside the negative pressure cavity 8. Human tissue fluid can enter the negative pressure cavity 8 through the collecting holes 13, thereby realizing the sampling of human biopsy.

[0029] The injection head 6 also includes a clamping assembly 10, which includes a clamping shaft 14, a first clamping plate 15, a reset spring 16 and a second clamping plate 17. The first clamping plate 15 is fixed to the side wall of the annular piston 9, and the second clamping plate 17 is located on the side of the first clamping plate 15 away from the middle of the negative pressure chamber 8, and the second clamping plate 17 is fixed to the first clamping plate 15 through the reset spring 16. The clamping shaft 14 passes through the first clamping plate 15, the reset spring 16 and the second clamping plate 17 in sequence, and the clamping shaft 14 is fixed to the first clamping plate 15. The connecting plate 15 is slidably connected and fixedly connected to the second clamping plate 17. A groove 18 matching the clamping shaft 14 is provided on the inner wall of the negative pressure chamber 8. When the clamping shaft 14 follows the annular piston 9 to move to the position of the groove 18, one end of the clamping shaft 14 enters the groove 18 under the elastic force of the reset spring 16, which plays a role in positioning the annular piston 9. When the drug delivery tube 3 is pulled back, since the position of the annular piston 9 is fixed, the drug delivery tube 3 can only slide relative to the sealing ring 12, thereby preventing the annular piston 9 from returning to the initial position to discharge the human tissue fluid.

[0030] The injection head 6 also includes a splitting assembly 11, which includes a receiving tube 19, a shunt cavity 20 and a shunt tube 21. One end of the receiving tube 19 is fixed to the negative pressure cavity 8. The shunt cavity 20 is sleeved on the inner side of the receiving tube 19 and is slidably connected to the inner wall of the receiving tube 19. One end of the drug delivery tube 3 close to the negative pressure cavity 8 is fixed to the shunt cavity 20 and communicates with the inside of the shunt cavity 20. A plurality of shunt tubes 21 are provided, and the plurality of shunt tubes 21 are fixed at equal angles. At one end of the shunt cavity 20 away from the dosing tube 3, multiple shunt tubes 21 are respectively connected to the interior of the shunt cavity 20. The shunt tubes 21 are made of memory alloy and have a flat end face. When the dosing tube 3 is pushed forward, the shunt cavity 20 can be driven to slide in the receiving tube 19, thereby moving the shunt tube 21 out of the receiving tube 19. Multiple shunt tubes 21 spread outward, making the drug injection area wider. After the drug injection is completed, the shunt tubes 21 can be pulled back into the receiving tube 19.

[0031] Limiting blocks 22 are fixed on the inner sides of both ends of the receiving tube 19 to prevent the diversion cavity 20 from being separated from the receiving tube 19 when the diversion cavity 20 moves in the receiving tube 19 .

[0032] The handle 7 includes a mounting tube 23, a support rod 24, a drive block 25 and a drive assembly 26. The end of the outer sleeve 2 away from the negative pressure chamber 8 is fixed to the support tube 28. An opening 41 is provided at a local position on the outside of the support tube 28. The drive block 25 is located in the middle of the inside of the mounting tube 23, and the drive block 25 is slidably sleeved on the outside of the support rod 24. The two ends of the support rod 24 are respectively fixed to the inner wall of the mounting tube 23. The end of the dosing tube 3 away from the diversion chamber 20 passes through the drive block 25 and the mounting tube 23, and is fixedly connected to the drive block 25 and slidably connected to the mounting tube 23. The drive assembly 26 is fixed on the mounting tube 23, and the output end of the drive assembly 26 is movably connected to the drive block 25.

[0033] The driving assembly 26 includes an annular knob 27 and a supporting tube 28. The outer side of the driving block 25 is provided with an external thread, and the inner side of the annular knob 27 is provided with an internal thread. The annular knob 27 is sleeved on the outer side of the driving block 25 and is threadedly connected to the driving block 25. The supporting tube 28 is sleeved on the outer side of the driving block 25, and one end of the supporting tube 28 is fixed to the side wall of the annular knob 27, and the other end is rotatably connected to the inner wall of the mounting tube 23 through a bearing.

[0034] Since the driving block 25 is threadedly connected to the annular knob 27, the driving block 25 can be driven to move back and forth on the support rod 24 by rotating the annular knob 27. The dosing tube 3 is fixedly connected to the driving block 25, so that the movement of the driving block 25 on the support rod 24 realizes the advancement and retraction of the dosing tube 3.

[0035] Annular baffles 29 are fixedly sleeved on the outer sides of both ends of the driving block 25 to prevent the driving block 25 from being separated from the annular knob 27 .

[0036] A positioning assembly 30 is provided on the outer side of the annular knob 27, and the positioning assembly 30 includes an arc-shaped rubber block 31, a first support block 32, a second support block 33, an arc-shaped mounting block 34, a fixed shaft 35, a connecting shaft 36, a buffer spring 37, an extrusion plate 38 and a fixed plate 39. The first support block 32 and the second support block 33 are symmetrically distributed on the outer side of the annular knob 27, and the first support block 32 and the second support block 33 are both fixed to the outer wall of the mounting cylinder 23, one end of the fixed shaft 35 and the connecting shaft 36 are respectively rotatably connected to the two ends of the arc-shaped mounting block 34 through a pin shaft, the end of the fixed shaft 35 away from the arc-shaped mounting block 34 is fixed to the first support plate, the fixed plate 39 is fixed to the end of the connecting shaft 36 away from the arc-shaped mounting block 34, and the buffer spring 37 and the extrusion plate 38 are both sleeved on the connecting shaft 3 6, the two ends of the buffer spring 37 are fixed to the fixing plate 39 and the extrusion plate 38 respectively, the extrusion plate 38 is slidably connected to the connecting shaft 36, the end of the first supporting block 32 away from the mounting tube 23 is provided with a through groove 40, the arc rubber block 31 is fixed to the inner side of the arc mounting block 34, after the position adjustment of the drug delivery tube 3 is completed, the position of the annular knob 27 can be fixed by the positioning assembly 30 to prevent the shunt tube 21 from moving when injecting the drug, when fixed, the arc rubber block 31 is in close contact with the annular knob 27 by rotating the arc mounting block 34, and then the connecting shaft 36 is rotated into the through groove 40, the extrusion plate 38 is against the second supporting block 33 under the elastic force of the buffer spring 37, and the position of the arc mounting block 34 is limited, thereby achieving the fixing of the annular knob 27.

[0037] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0038] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A drug injection device, comprising a catheter assembly (1), an injection head (6) and a handle (7), characterized in that: The catheter assembly (1) comprises an outer sleeve (2), a drug delivery tube (3) and a filler (4); the filler (4) is filled inside the outer sleeve (2); a catheter channel (5) is provided in the middle of the filler (4); the drug delivery tube (3) is sleeved on the inner side of the catheter channel (5) and is slidably connected to the inner wall of the catheter channel (5); one end of the catheter assembly (1) is connected to an injection head (6), and the other end is connected to a handle (7); The injection head (6) comprises a negative pressure chamber (8), an annular piston (9), a clamping assembly (10) and a splitting assembly (11); one end of the outer sleeve (2) is fixed to the negative pressure chamber (8); one end of the drug delivery tube (3) passes through the negative pressure chamber (8) and is connected to the input end of the splitting assembly (11); the splitting assembly (11) is fixed to the negative pressure chamber (8); the annular piston (9) is located on the inner side of the negative pressure chamber (8); a sealing ring (12) is fixed on the inner side of the annular piston (9); the annular piston (9) is interference fit with the outer wall of the drug delivery tube (3) through the sealing ring (12); and the annular piston (9) is slidingly fit with the inner wall of the negative pressure chamber (8); a plurality of collecting holes (13) are provided at equal angles on the outer side of the negative pressure chamber (8) near one end of the outer sleeve (2); and the clamping assembly (10) is fixed to the annular piston (9).

2. A drug injection device according to claim 1, characterized in that: The clamping assembly (10) comprises a clamping shaft (14), a first clamping plate (15), a return spring (16) and a second clamping plate (17); the first clamping plate (15) is fixed to the side wall of the annular piston (9); the second clamping plate (17) is located on a side of the first clamping plate (15) away from the middle of the negative pressure chamber (8); and the second clamping plate (17) is fixed to the first clamping plate (15) via the return spring (16); the clamping shaft (14) passes through the first clamping plate (15), the return spring (16) and the second clamping plate (17) in sequence; the clamping shaft (14) is slidably connected to the first clamping plate (15) and fixedly connected to the second clamping plate (17); and a groove (18) matching the clamping shaft (14) is provided on the inner wall of the negative pressure chamber (8).

3. A drug injection device according to claim 2, characterized in that: The splitting assembly (11) comprises a receiving tube (19), a shunt chamber (20) and a shunt tube (21); one end of the receiving tube (19) is fixed to the negative pressure chamber (8); the shunt chamber (20) is sleeved on the inner side of the receiving tube (19) and is slidably connected to the inner wall of the receiving tube (19); one end of the drug delivery tube (3) close to the negative pressure chamber (8) is fixed to the shunt chamber (20) and is in communication with the interior of the shunt chamber (20); a plurality of shunt tubes (21) are provided, and the plurality of shunt tubes (21) are fixed at equal angles to one end of the shunt chamber (20) away from the drug delivery tube (3); the plurality of shunt tubes (21) are respectively in communication with the interior of the shunt chamber (20); the shunt tubes (21) are made of memory alloy and have flat end faces.

4. A drug injection device according to claim 3, characterized in that: Limiting blocks (22) are fixed on the inner sides of both ends of the storage tube (19).

5. A drug injection device according to claim 4, characterized in that: The handle (7) comprises a mounting tube (23), a support rod (24), a driving block (25) and a driving assembly (26); one end of the outer sleeve (2) away from the negative pressure chamber (8) is fixed to the supporting tube (28); an opening (41) is provided at a local position on the outside of the supporting tube (28); the driving block (25) is located in the middle of the inside of the mounting tube (23), and the driving block (25) is slidably sleeved on the outside of the supporting rod (24); both ends of the supporting rod (24) are respectively fixed to the inner wall of the mounting tube (23); one end of the drug delivery tube (3) away from the shunt chamber (20) passes through the driving block (25) and the mounting tube (23), and is fixedly connected to the driving block (25) and slidably connected to the mounting tube (23); the driving assembly (26) is fixed to the mounting tube (23), and the output end of the driving assembly (26) is movably connected to the driving block (25).

6. A drug injection device according to claim 5, characterized in that: The driving assembly (26) comprises an annular knob (27) and a supporting tube (28); the outer side of the driving block (25) is provided with an external thread; the inner side of the annular knob (27) is provided with an internal thread; the annular knob (27) is sleeved on the outer side of the driving block (25) and is threadedly connected to the driving block (25); the supporting tube (28) is sleeved on the outer side of the driving block (25); one end of the supporting tube (28) is fixed to the side wall of the annular knob (27); and the other end is rotatably connected to the inner wall of the mounting tube (23) via a bearing.

7. A drug injection device according to claim 6, characterized in that: Annular baffles (29) are fixedly sleeved on the outer sides of both ends of the driving block (25).

8. A drug injection device according to claim 7, characterized in that: A positioning assembly (30) is provided on the outer side of the annular knob (27), and the positioning assembly (30) comprises an arc-shaped rubber block (31), a first support block (32), a second support block (33), an arc-shaped mounting block (34), a fixed shaft (35), a connecting shaft (36), a buffer spring (37), an extrusion plate (38) and a fixed plate (39), wherein the first support block (32) and the second support block (33) are symmetrically distributed on the outer side of the annular knob (27), and the first support block (32) and the second support block (33) are both fixed to the outer wall of the mounting tube (23), and one end of the fixed shaft (35) and the connecting shaft (36) are respectively connected to the arc-shaped mounting block (31) through a pin. 4), the two ends of the fixed shaft (35) are rotatably connected, one end of the fixed shaft (35) away from the arc-shaped mounting block (34) is fixed to the first support plate, the fixed plate (39) is fixed to the end of the connecting shaft (36) away from the arc-shaped mounting block (34), the buffer spring (37) and the extrusion plate (38) are both sleeved on the outside of the connecting shaft (36), the two ends of the buffer spring (37) are respectively fixed to the fixed plate (39) and the extrusion plate (38), the extrusion plate (38) is slidably connected to the connecting shaft (36), the end of the first support block (32) away from the mounting cylinder (23) is provided with a through groove (40), and the arc-shaped rubber block (31) is fixed to the inner side of the arc-shaped mounting block (34).

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