A pipette tip transfer device

Abstract

The present invention provides a pipette tip transfer device, comprising an annular outer frame, in which a gun taking device is arranged, the gun taking device comprises a plurality of guide plates arranged side by side, each guide plate is provided with a plurality of downwardly extending taking needles; and also comprises a gun pushing assembly, comprising a baffle and a push rod, the push rod is slidably connected to the annular outer frame in a vertical direction, the baffle is horizontally connected to the bottom end of the push rod and is located below the guide plate, a through groove is provided at a position corresponding to each through hole on the baffle, and a plurality of taking needles pass through the through groove. When in use, the head end of the pipette tip is placed neatly downward, and then the bottom end of the taking needle is aligned with the tail end of the pipette tip, the taking needle is inserted into the pipette tip and fixed, the pipette tip transfer device is lifted, the pipette tip is placed in a special box body, and then the annular outer frame is held and the push rod is pushed downward, the baffle moves downward, the pipette tip is scraped off the taking needle, and falls into the special box body, thereby completing the transfer of the pipette tip.

Description

Technical Field

[0001] The invention relates to the technical field of transfer of liquid transfer gun tips, in particular to a liquid transfer gun tip transfer device. Background Art

[0002] Pipette tips are widely used in biological, medical, and chemical experiments to transfer solution reagents quantitatively, and they play an important role in controlling the dosage of experimental solutions. In practice, newly purchased pipette tips are placed in packaging bags in a disordered manner. For ease of use, the tips need to be placed neatly and orderly in a special box. This step is currently basically done manually, and they need to be inserted into the box one by one. In order to avoid contamination during pipetting, the pipette tips must be discarded after a suction and discharge operation. Therefore, in experiments that require multiple pipetting operations, the use of pipette tips becomes very considerable, increasing the workload of manually placing pipette tips.

[0003] Therefore, how to solve the problem in the prior art that the messy pipette tips need to be manually placed in a special box has become a technical problem that technicians in this field urgently need to solve. Summary of the invention

[0004] The object of the present invention is to provide a pipette tip transfer device to solve the problem in the prior art that messy pipette tips need to be manually placed in a special box.

[0005] The various technical effects that can be produced by the preferred technical solutions among the various technical solutions provided by the present invention are described in detail below.

[0006] To achieve the above object, the present invention provides the following technical solutions:

[0007] The present invention provides a pipette tip transfer device, comprising:

[0008] Annular outer frame;

[0009] The gun taking device arranged on the inner side of the annular outer frame comprises a plurality of guide plates arranged side by side, each of the guide plates is provided with a plurality of through holes vertically penetrating the guide plates, and each of the through holes is provided with a downwardly extending taking needle;

[0010] The gun push assembly includes a baffle and a push rod, the push rod is slidably connected to the annular outer frame in the vertical direction, the baffle is arranged below the guide plate and connected to the bottom end of the push rod, and the baffle is provided with a through groove that slides along the vertical direction with the retrieval needle, and the width of the through groove is greater than the outer diameter of the retrieval needle and smaller than the tail end diameter of the pipette tip.

[0011] Preferably, the multiple guide plates include a fixed guide plate fixedly connected to the inner side of the annular outer frame, an active guide plate arranged parallel to the fixed guide plate, and a plurality of driven guide plates arranged between the active guide plate and the fixed guide plate. The active guide plate and the driven guide plate are both slidably connected to the annular outer frame, and the sliding direction is along a direction perpendicular to the fixed guide plate. The through groove is a long strip groove extending in a direction perpendicular to the fixed guide plate.

[0012] Preferably, a linkage limiting device is provided between the active guide vane and the driven guide vane, between a plurality of driven guide vanes, and between the driven guide vane and the fixed guide vane.

[0013] Preferably, the linkage limit device includes a limit screw and a limit ring, and the fixed guide plate, the multiple driven guide plates and the active guide plate are provided with the limit screws at both ends along their own length direction, and a limit ring is sleeved on the outer side of each two adjacent limit screws, and the length of each limit ring is greater than the sum of the diameters of the two limit screws.

[0014] Preferably, a spacer needle is provided between every two adjacent guide plates, and the guide plates and the spacer needles are detachably connected.

[0015] Preferably, wrenches for pulling the active guide vane to slide are provided at both ends of the active guide vane along the length direction.

[0016] Preferably, blocking and limiting structures are provided at the top and middle of the needle removal needle, and the distance between the two blocking and limiting structures is greater than the height of the guide piece.

[0017] Preferably, the push rods include two pairs, and a handle is provided between the top ends of each pair of push rods.

[0018] Preferably, sliding rods are provided at both ends of the guide plate in the annular outer frame along the length direction, and the sliding rods extend in a direction perpendicular to the guide plate. Sliding holes are provided at both ends of the guide plate in the length direction, and the sliding rods are inserted into the sliding holes and the guide plate can slide along the sliding rods.

[0019] Preferably, the bottom of the removal needle is conical.

[0020] The present invention provides a pipette tip transfer device, which has the following beneficial effects:

[0021] The present invention provides a pipette tip transfer device, comprising an annular outer frame, a gun taking device is arranged on the inner side of the annular outer frame, the gun taking device comprises a plurality of guide plates arranged side by side, each guide plate is provided with a plurality of through holes penetrating the guide plates in a vertical direction, and a downwardly extending taking needle is arranged in the through hole; the pipette tip transfer device also comprises a gun pushing assembly, the gun pushing assembly comprises a baffle and a push rod, the push rod is slidably connected to the annular outer frame in a vertical direction, the baffle is located below the plurality of guide plates and is connected to the bottom end of the push rod, a through groove is arranged on the baffle that slides in a vertical direction with the taking needle, the plurality of taking needles on the guide plate pass through the through groove, the width of the through groove is greater than the outer diameter of the taking needle and smaller than the tail end diameter of the pipette tip, and when in use, the pipette tip transfer device The head end of the gun tip is placed neatly facing downwards, and then the bottom end of the needle is aligned with the tail end of the pipette tip, the needle is inserted into the pipette tip, and the outer wall of the needle is supported at the tail end opening of the pipette tip. Then the pipette tip transfer device is lifted, and the pipette tip moves with the device. When it reaches the top of the special box body for placing the pipette tip, the pipette tip is placed in the special box body, and then the annular outer frame is held, and the push rod is pushed downward, and the baffle moves downward. Since the width of the through groove is smaller than the diameter of the tail end of the pipette tip, the baffle will scrape the pipette tip off the needle when it moves downward, and it will fall into the special box body, completing the transfer of the pipette tip, replacing the problem of manual placement one by one, and greatly improving the transfer efficiency.

[0022] It should be understood that the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0024] Figure 1 is a structural diagram of a pipette tip transfer device shown in an embodiment of the present invention;

[0025] Figure 2 is an exploded view of a transfer device for a pipette tip shown in an embodiment of the present invention;

[0026] Figure 3 is a structural diagram of an annular outer frame shown in an embodiment of the present invention;

[0027] Figure 4 is a structural diagram of a baffle according to an embodiment of the present invention;

[0028] Figure 5 is a perspective structural diagram of a fixed guide blade shown in an embodiment of the present invention;

[0029] Figure 6 is a perspective structural diagram of a driven guide vane shown in an embodiment of the present invention;

[0030] Figure 7 is a perspective structural diagram of an active guide blade shown in an embodiment of the present invention;

[0031] Figure 8 is a needle removal structure diagram shown in an embodiment of the present invention;

[0032] Fig. 9 1 is a diagram of a needle spacing structure shown in an embodiment of the present invention;

[0033] Fig.10 1 is a structural diagram of a pipette tip according to an embodiment of the present invention.

[0034] In the figure: 1. annular outer frame; 2. through hole; 3. needle removal; 4. baffle; 5. push rod; 6. through slot; 7. fixed guide; 8. driven guide; 9. active guide; 10. limit screw; 11. limit ring; 12. spacer needle; 13. wrench; 14. annular limit slot; 16. handle; 17. slide rod; 18. slide hole. DETAILED DESCRIPTION

[0035] To make the purpose, technical solution and advantages of the present invention clearer, the technical solution of the present invention will be described in detail below. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other implementation methods obtained by ordinary technicians in this field without creative work belong to the scope of protection of the present invention.

[0036] The following is an explanation of the embodiments with reference to the accompanying drawings. In addition, the embodiments shown below do not limit the invention described in the claims. In addition, the entire contents of the configurations shown in the following embodiments are not limited to the solutions required as the invention described in the claims.

[0037] See also Figures 1 to 10The present invention provides a pipette tip transfer device, comprising an annular outer frame 1, the inner side of the annular outer frame 1 may be a rectangular through groove, a gun taking device is arranged in the rectangular through groove, the gun taking device may include a plurality of guide plates arranged side by side, the plurality of guide plates may be parallel to one of the side surfaces of the rectangular through groove, a plurality of through holes 2 penetrating the guide plates in the vertical direction may be evenly arranged on each guide plate along the length direction of the guide plate, a downwardly extending taking needle 3 is arranged in the through hole 2; the pipette tip transfer device also includes a gun pushing assembly, the gun pushing assembly includes a baffle 4 and a push rod 5, the push rod 5 penetrates the annular outer frame 1 in the vertical direction and is slidably connected to the annular outer frame 1, the baffle 4 is horizontally connected to the bottom end of the push rod 5 and the baffle 4 is located below the plurality of guide plates, a plurality of through grooves 6 sliding in the vertical direction with the taking needles may be arranged on the baffle 4, the bottom ends of the plurality of taking needles 3 all extend downward through the through grooves The width of the groove 6 is larger than the outer diameter of the needle 3 and smaller than the tail end diameter of the pipette tip. When in use, the head end of the pipette tip is placed neatly downwards, and then the bottom end of the needle 3 is aligned with the tail end of the pipette tip, the needle 3 is inserted into the pipette tip, and the outer wall of the needle 3 is supported at the tail end opening of the pipette tip. Then the pipette tip transfer device is lifted, and the pipette tip moves with the device. When it reaches the top of the special box body for placing the pipette tip, the pipette tip is placed in the special box body, and then the annular outer frame 1 is held, and the push rod 5 is pushed downward, and the baffle 4 moves downward. Since the width of the through groove 6 is smaller than the tail end diameter of the pipette tip, when the baffle 4 moves downward, the pipette tip will be scraped off the needle 3 and fall into the special box body, completing the transfer of the pipette tip, replacing the problem of manual placement one by one, and greatly improving the transfer efficiency.

[0038] As an optional embodiment, the guide vanes may include three types, namely, a fixed guide vane 7, a driven guide vane 8, and an active guide vane 9. The cross-section of the rectangular through slot may be a rectangle, or a rounded rectangle, etc. Each of the guide vanes may extend along the length direction of the rectangular through slot and be evenly arranged along the width direction of the rectangular through slot. For example, from left to right, there may be a fixed guide vane 7, a plurality of driven guide vanes 8, and an active guide vane 9. The fixed guide vane 7 is fixedly connected to the inner side wall of the annular outer frame 1 and may be bolted. The plurality of driven guide vanes 8 and the active guide vane 9 may be connected to the inner side wall of the annular outer frame 1. The sheets 9 are all slidably connected to the annular outer frame 1, and the sliding direction can be along a direction perpendicular to the fixed guide sheet 7, for example, along the width direction of the rectangular through groove. The above-mentioned through groove 6 can be a long strip groove, and the center points of the through holes 2 on the above-mentioned multiple guide sheets can form a regular rectangular grid. The through groove 6 extends along a direction perpendicular to the fixed guide sheet 7. The direction perpendicular to the fixed guide sheet 7 is referred to as a row, and the direction parallel to the fixed guide sheet 7 is referred to as a column. Each row of through holes 2 corresponds to a through groove 6. When the guide sheet slides in a direction parallel to the fixed guide sheet, the needle can slide in the through groove 6.

[0039] In implementation, a linkage limit device can be set between the active guide piece 9 and the adjacent driven guide piece 8, between multiple driven guide pieces 8, and between the fixed guide piece 7 and the adjacent driven guide piece 8. When the active guide piece 9 is pulled in the direction away from the fixed guide piece 7, the driven guide piece 8 also follows the active guide piece 9 to move in the direction away from the fixed guide piece 7. When it moves to a certain distance, the linkage limit device restricts it from continuing to move. In this way, the distance between the driven guide pieces 8, between the driven guide piece 8 and the active guide piece 9, and between the driven guide piece 8 and the fixed guide piece 7 can be adjusted to fix the needle removal 3 on the guide piece. It can be aligned with the hole on the special box, and the pipette tip can be accurately placed in the special box. For example, the number of the above-mentioned driven guide pieces 8 can be six. The above-mentioned linkage limit device includes a limit screw 10 and a limit ring 11. Each guide piece is provided with a limit screw 10 at the top of both ends along its own length direction in the vertical direction. The bottom of the limit screw 10 extends into the corresponding guide piece and the top extends outward. The above-mentioned limit ring 11 can include multiple limit rings 11, and multiple limit rings 11 are staggered up and down. For example, the fixed guide piece 7 can be guide piece No. 1, and the driven guide piece 8 is from close to the fixed guide piece 7 to far away. The directions of the fixed guide blade 7 can be guide blade No. 2, guide blade No. 3, guide blade No. 4, guide blade No. 5, guide blade No. 6, and guide blade No. 7 in sequence, the active guide blade 9 can be guide blade No. 8, and the limiting ring 11 is provided with two layers, namely the bottom layer close to the guide blade and the top layer above the bottom layer. In one implementation mode, a limiting ring 11 is respectively provided on the outer side of the limiting screws 10 on guide blade No. 1 and guide blade No. 2, guide blade No. 3 and guide blade No. 4, guide blade No. 5 and guide blade No. 6, guide blade No. 7 and guide blade No. 8 of the bottom layer, and a limiting ring 11 is respectively provided on the outer side of the limiting screws 10, and the guide blade No. 2 and guide blade No. 3, guide blade No. 4 and guide blade No. 5, guide blade No. 6 and guide blade No. 7 of the top layer A limiting ring 11 is arranged on the outside of each limiting screw 10 on the plate. The limiting ring 11 can be a waist-shaped ring. The length of the limiting ring 11 is greater than the sum of the diameters of the two limiting screws 10. When the active guide plate 9 is moved away from the fixed guide plate 7, the limiting ring 11 drives the driven guide plate 8 to move away from the fixed guide plate 7 in sequence, and stops moving when it moves to the maximum length of each limiting ring 11. At this time, the lateral distance between the needle 3 connected to the guide plate is equal to the lateral distance of the placement hole on the special box, so the pipette tip on the needle 3 can be accurately placed in the placement hole.

[0040] The above-mentioned limit screw 10 and limit ring 11 can limit the maximum lateral distance between the guide pieces. The following structure can be used to limit the minimum lateral distance between the guide pieces. A spacer needle 12 can be set on each driven guide piece 8. The spacer needle 12 can be a U-shaped structure. The opening of the spacer needle 12 is downwardly across the driven guide piece 8. The top of the spacer needle 12 is detachably connected to the top of the driven guide piece 8. The two side parts of the spacer needle 12 are inserted into the two sides of the corresponding guide piece. When the active guide piece 9 is moved in the direction close to the fixed guide piece 7, the active guide piece 9 contacts the spacer needle 12 on the adjacent driven guide piece 8, and drives the adjacent driven guide piece 8 to move in the direction close to the active guide piece 9, so as to By analogy, the movement of the spacer needle 12 on the driven guide piece 8 adjacent to the fixed guide piece 7 stops after contacting the fixed guide piece 7. At this time, the lateral distance between the guide pieces is the minimum distance, and the retrieval needle 3 connected to the guide piece is aligned with the arranged pipette tip, so as to facilitate the insertion of the retrieval needle 3 into the pipette tip. It should be noted that the cross-section of the spacer needle 12 can be circular, and spacer needles 12 of different diameters can be used to adjust the minimum distance between the guide pieces. For example, a fixing groove can be set at the top of the driven guide piece 8, and the top of the spacer needle 12 is fixed in the fixing groove, or a circular hole can be set at the top of the guide piece, and a downward protrusion is set at the bottom of the top of the spacer needle 12, and the protrusion is inserted into the circular hole for fixation.

[0041] Furthermore, wrenches 13 for pulling the active guide piece 9 to slide can be provided at both ends of the active guide piece 9 along the length direction. The wrench 13 can be a rectangular protrusion, and the wrench 13 protrudes from the end surface of the driven guide piece 8 along the length direction. With such a configuration, when the active guide piece 9 is moved, the wrench 13 can be used as a fulcrum to facilitate movement.

[0042] During implementation, the top and middle parts of the above-mentioned needle 3 are provided with blocking and limiting structures. When the needle 3 is not in contact with the pipette tip, the needle 3 slides downward along the through hole 2 under the action of its own gravity, and stops when it slides to the blocking and limiting structure above and contacts the guide plate. When the needle 3 contacts the pipette tip, the needle 3 is pushed upward, and stops when it slides to the blocking and limiting structure below and contacts the guide plate. The blocking and limiting structure can be an inwardly recessed annular limiting groove 14 and an elastic retaining ring arranged in the annular limiting groove 14. The top end of the needle 3 passes through the top of the through hole 2 upward, and the outer diameter of the elastic retaining ring is larger than The inner diameter of the through hole 2 can prevent the needle 3 from falling out of the through hole 2. The annular groove in the middle of the needle 3 passes downward through the bottom of the through hole 2. The distance between the two annular grooves is greater than the height of the guide plate, so that the needle 3 can float within a certain range when it contacts the pipette tip. When the arranged pipette tips are inconsistent in height, it can ensure that each needle 3 can be inserted into the pipette tip. When in use, the needle 3 is aligned with the arranged pipette tips, and the annular outer frame is moved downward. After each needle 3 contacts the pipette tip, press down on the top of the needle 3 to insert the bottom of the needle 3 into the pipette tip.

[0043] In implementation, the above-mentioned push rods 5 can include two pairs, and the two push rods 5 of each pair of push rods 5 can be respectively arranged on the two side edges of the annular outer frame 1 in a direction perpendicular to the guide plate, and the two pairs of push rods 5 are symmetrically arranged on both sides of the annular outer frame 1 along the length direction. A handle 16 is arranged between each pair of push rods 5, and the handle 16 can be a connecting rod. The two ends of the connecting rod are respectively connected to the top of the push rod 5. When the pipette tip is moved to the special box, the annular outer frame 1 can be held still, and the handle 16 is pressed downward. The push rod 5 drives the baffle 4 to move downward, scrapes the pipette tip on the needle 3, and drops it into the special box to complete the transfer operation.

[0044] The sliding connection between the guide plate and the annular outer frame 1 can be achieved by using a slide rod 17. A slide rod 17 is arranged at each end of the guide plate in the rectangular through groove along the length direction. The slide rod 17 extends in a direction perpendicular to the guide plate. Slide holes 18 are arranged at positions corresponding to the guide plate and the slide rod 17. The slide rod 17 is inserted into each slide hole 18 and connected to the annular outer frame 1 at both ends. The guide plate can slide along the slide rod 17.

[0045] The top of the above-mentioned needle 3 can be cylindrical and the bottom can be conical, so that the needle 3 can stably fix the pipette tip after being inserted into the pipette tip to prevent the pipette tip from deflecting.

[0046] The above is only a specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art can easily think of changes or substitutions within the technical scope disclosed by the present invention, which should be included in the protection scope of the present invention. Therefore, the protection scope of the present invention should be based on the protection scope of the claims.

Claims

1. A pipette tip transfer device, characterized in that: include: Annular outer frame (1); The gun taking device arranged on the inner side of the annular outer frame comprises a plurality of guide plates arranged side by side, each of the guide plates is provided with a plurality of through holes (2) vertically penetrating the guide plates, each of the through holes (2) is provided with a downwardly extending taking needle (3), the top and middle of the taking needle (3) are provided with blocking and limiting structures, and the distance between the two blocking and limiting structures is greater than the height of the guide plates; A gun push assembly, comprising a baffle (4) and a push rod (5), wherein the push rod (5) is slidably connected to the annular outer frame (1) in a vertical direction, the baffle (4) is arranged below the guide plate and connected to the bottom end of the push rod (5), and the baffle (4) is provided with a through groove (6) which slides with the needle in a vertical direction, and the width of the through groove (6) is greater than the outer diameter of the needle (3) and smaller than the tail end diameter of the pipette tip; The plurality of guide blades include a fixed guide blade (7) fixedly connected to the inner side of the annular outer frame, an active guide blade (9) arranged parallel to the fixed guide blade (7), and a plurality of driven guide blades (8) arranged between the active guide blade (9) and the fixed guide blade (7); the active guide blade (9) and the driven guide blade (8) are both slidably connected to the annular outer frame (1), and the sliding direction is along a direction perpendicular to the fixed guide blade (7); the through groove (6) is a long strip groove extending along a direction perpendicular to the fixed guide blade (7).

2. The pipette tip transfer device according to claim 1, characterized in that: A linkage limiting device is provided between the active guide piece (9) and the driven guide piece (8), between a plurality of the driven guide pieces (8), and between the driven guide piece (8) and the fixed guide piece (7).

3. The pipette tip transfer device according to claim 2, characterized in that: The linkage limiting device comprises a limiting screw (10) and a limiting ring (11); the fixed guide piece (7), the plurality of driven guide pieces (8) and the active guide piece (9) are provided with the limiting screws (10) at both ends along their length direction; a limiting ring (11) is sleeved on the outer side of each two adjacent limiting screws (10); and the length of each limiting ring (11) is greater than the sum of the diameters of the two limiting screws (10).

4. The pipette tip transfer device according to claim 1, characterized in that: A spacer needle (12) is provided between each two adjacent guide plates, and the guide plates and the spacer needle (12) are detachably connected.

5. The pipette tip transfer device according to claim 1, characterized in that: Wrenches (13) for pulling the active guide piece (9) to slide are arranged at both ends of the active guide piece (9) along the length direction.

6. The pipette tip transfer device according to claim 1, characterized in that: The push rods (5) include two pairs, and a handle (16) is provided between the top ends of each pair of push rods (5).

7. The pipette tip transfer device according to claim 1, characterized in that: Slide rods (17) are provided at both ends of the guide blade along the length direction in the annular outer frame (1), and the slide rods (17) extend in a direction perpendicular to the guide blade. Slide holes (18) are provided at both ends of the guide blade along the length direction, and the slide rods (17) are inserted into the slide holes (18) and the guide blade can slide along the slide rods (17).

8. The pipette tip transfer device according to claim 1, characterized in that: The bottom of the needle (3) is conical.

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