Waste liquid discharge system for chemiluminescence analyzer
The negative pressure liquid extraction system solves the problems of incomplete waste liquid extraction and cross-contamination in traditional chemiluminescence analyzers, and achieves rapid and complete waste liquid discharge, improving the reliability and competitiveness of the equipment.
Patent Information
- Application Number
- CN202010954956.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2020-09-11
- Publication Date
- 2025-08-12
- Estimated Expiration
- 2040-09-11
AI Technical Summary
The cleaning waste liquid discharge system of traditional chemiluminescence analyzers has the risk of long extraction time, pipeline resistance affecting the power attenuation of the diaphragm pump, sample needle wall hanging and cross-contamination, affecting the reliability of the detection results and the cleanliness of the equipment.
A negative pressure liquid extraction system is adopted, including a negative pressure pump, a negative pressure energy storage container and a waste liquid storage container. A negative pressure system is established through a negative pressure pump, and the waste liquid is quickly extracted and the pressure of the energy storage container is compensated to ensure that the waste liquid is completely extracted and avoid sample needle hanging on the wall.
It realizes rapid and complete extraction of waste liquid, avoids sample needle hanging walls and cross-contamination, and improves the reliability and competitiveness of the equipment.
Smart Images

Figure CN111948417B_ABST
Abstract
Description
Technical Field
[0001] The invention relates to a chemiluminescence analyzer, in particular to a waste liquid discharge system for the chemiluminescence analyzer. Background Art
[0002] A chemiluminescent label analyzer, also known as a chemiluminescence analyzer (CLIA), is a commonly used in vitro diagnostic device. The fluidic system of a chemiluminescence analyzer is a crucial component that impacts its proper function. It primarily includes a magnetic bead cleaning module, a liquid injection module, and a wastewater discharge module.
[0003] The traditional cleaning waste liquid discharge system uses a connecting pipe to connect a diaphragm pump to the cleaning tank, and a solenoid valve is installed on the pipe. In other words, the diaphragm pump is used as the direct power, and through its cooperation with the solenoid valve, the liquid in the cleaning tank is discharged into a designated container. However, it has been verified that the above system has the following problems in actual operation:
[0004] The rapid development of high-throughput instruments has greatly shortened the time for waste liquid extraction. Coupled with the influence of pipeline resistance, the power of the diaphragm pump decays with the extension of usage, resulting in the waste liquid in the cleaning tank not being extracted in time or residual, further causing the outer wall of the sampling needle to stick to the wall, posing a risk of sample cross-contamination, affecting the reliability of the test results. Liquid is also easily dropped on the surface of the instrument, affecting cleanliness and further affecting the competitiveness of the company. Summary of the Invention
[0005] The object of the present invention is to provide a waste liquid discharge system for a chemiluminescence analyzer, wherein the waste liquid pumping system utilizes negative pressure compensation to pump liquid, which can not only improve the pumping efficiency, but also improve the pumping efficiency.
[0006] To achieve the above object, the present invention adopts the following technical solutions:
[0007] The waste liquid discharge system for a chemiluminescence analyzer of the present invention comprises a negative pressure liquid pumping system communicated with a cleaning container and a liquid drainage system communicated with the negative pressure liquid pumping system.
[0008] Furthermore, the negative pressure liquid extraction system includes a negative pressure pump, a negative pressure energy storage container and a waste liquid storage container which are sequentially connected through a negative pressure pipeline, and the liquid inlet of the negative pressure pipeline is connected to the liquid discharge port of the cleaning container;
[0009] A first solenoid valve and a pressure reducing valve are arranged at intervals on the negative pressure pipeline between the negative pressure energy storage container and the waste liquid storage container, and a second solenoid valve is arranged on the negative pressure pipeline between the waste liquid storage container and the cleaning container.
[0010] Furthermore, a third solenoid valve is provided on the negative pressure pipeline between the negative pressure energy storage container and the negative pressure pump.
[0011] Furthermore, a first liquid level sensor and a first pressure sensor are provided in the negative pressure energy storage container, and a second liquid level sensor and a second pressure sensor are provided in the waste liquid storage container.
[0012] Furthermore, the pressure of the negative pressure energy storage container ≥ the pressure of the pressure reducing valve ≥ the pressure of the waste liquid storage container > the pressure of the cleaning container.
[0013] Furthermore, there is at least one negative pressure energy storage container.
[0014] Furthermore, the drainage system includes a drainage pump and a drainage pipeline, the inlet of the drainage pipeline is connected to the negative pressure energy storage container and the waste liquid storage container respectively, and the outlet thereof is connected to the inlet of the drainage pump.
[0015] Furthermore, the drainage pipeline includes a drainage main pipe connected to the drainage pump and two drainage branches connected to the drainage main pipe, and each of the drainage branches is provided with a fourth solenoid valve.
[0016] Furthermore, the first solenoid valve and the third solenoid valve are both two-position three-way solenoid valves, and the second solenoid valve and the fourth solenoid valve are both two-way solenoid valves.
[0017] Furthermore, the first solenoid valve and the third solenoid valve are normally open two-position three-way solenoid valves.
[0018] The advantage of the present invention is that it overcomes the technical defects of traditional positive pressure liquid extraction. During liquid extraction, a negative pressure system is established, and the negative pressure is used to quickly extract the waste liquid in the cleaning container into the waste liquid storage container. At the same time, the negative pressure energy storage container can also compensate for the negative pressure of the waste liquid storage container, further ensuring that the negative pressure system can extract the waste liquid in the cleaning container into the waste liquid storage container and the negative pressure energy storage container, thereby realizing rapid and complete extraction of waste liquid, effectively avoiding the outer wall of the sampling needle from sticking to the wall, further avoiding cross contamination, improving reliability, and thus improving equipment quality, thereby improving the competitiveness of this product among its peers.
[0019] The waste liquid storage container and the negative pressure energy storage container of the present invention both have a large volume and can store a certain amount of liquid, further ensuring complete liquid extraction; at the same time, the drainage pump is used to discharge the waste liquid in the waste liquid storage container and the negative pressure energy storage container directly into a designated container, avoiding direct connection of the drainage pump to the cleaning container, and the requirements for the drainage pump are relatively low. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] Figure 1 It is a structural schematic diagram of the present invention.
[0021] Figure 2 It is a circuit principle block diagram of the present invention. DETAILED DESCRIPTION
[0022] The following describes an embodiment of the present invention in detail with reference to the accompanying drawings. This embodiment is implemented based on the technical solution of the present invention, and provides a detailed implementation method and specific operation process. However, the protection scope of the present invention is not limited to the following embodiment.
[0023] like Figure 1 As shown, the waste liquid discharge system for a chemiluminescence analyzer according to the present invention includes a negative pressure liquid pumping system connected to a cleaning container 100 (i.e., a cleaning tank) and a liquid discharge system connected to the negative pressure liquid pumping system. The negative pressure liquid pumping system includes a negative pressure pump 201, a negative pressure energy storage container 202 (i.e., an energy storage tank, which can be one or two), and a waste liquid storage container 203 (i.e., a waste liquid tank, which can be one or two) connected in sequence through a negative pressure pipeline, and the liquid inlet of the negative pressure pipeline is connected to the liquid discharge port of the cleaning container 100;
[0024] A third solenoid valve 204 is installed on the negative pressure pipeline between the negative pressure energy storage container 202 and the negative pressure pump 201. A first solenoid valve 206 and a pressure reducing valve 205 are installed in between the negative pressure energy storage container 202 and the waste liquid storage container 203. A second solenoid valve 207 (a two-position solenoid valve) is installed on the negative pressure pipeline between the waste liquid storage container 203 and the cleaning container 100. Both the first solenoid valve 206 and the third solenoid valve 204 are normally open, two-position, three-way solenoid valves (i.e., they are closed when powered on and open when powered off).
[0025] During operation, a negative pressure system can be established first, that is, the negative pressure pump 201 is started, and a negative pressure system is established by cooperating with the first solenoid valve 206 and the third solenoid valve 204: the pressure of the negative pressure energy storage container 202 ≥ the pressure of the pressure reducing valve 205 ≥ the pressure of the waste liquid storage container 203 > the relative ambient pressure of the cleaning container 100.
[0026] like Figure 1 As shown, the drainage system includes a drainage pump 301 and a drainage pipeline. The drainage pipeline includes a drainage main pipe 302 connected to the liquid inlet of the drainage pump 301 and a drainage branch pipe 303.1 and a drainage branch pipe 303.2 connected to the drainage main pipe 302. The liquid inlet of the drainage branch pipe 303.1 is connected to the drainage port at the bottom of the negative pressure energy storage container 202, and the liquid inlet of the drainage branch pipe 303.2 is connected to the drainage port at the bottom of the waste liquid storage container 203. A fourth solenoid valve 304 is provided on each of the drainage branch pipes 303.1 and 303.2, and the opening and closing of the drainage pipeline is controlled by opening and closing the fourth solenoid valve 304.
[0027] like Figure 1As shown, a first liquid level sensor 401 for detecting liquid level information and a first pressure sensor 501 for detecting pressure are provided in the negative pressure energy storage container 202, and a second liquid level sensor 402 for detecting liquid level information and a second pressure sensor 502 for detecting pressure are provided in the waste liquid storage container 203.
[0028] In order to realize automatic pumping and automatic discharge of waste liquid, Figure 2 As shown, the signal output ends of the first pressure sensor 501, the second pressure sensor 502, the first liquid level sensor 401 and the second liquid level sensor 402 are electrically connected to the signal input ends of the control system (which can be a single-chip microcomputer or a control system of a chemiluminescence analyzer), and the control output end of the control system is electrically connected to the control input end of the negative pressure pump 201, the control input end of the displacement pump 301 and the first solenoid valve 206, the second solenoid valve 207, the third solenoid valve 204 and the fourth solenoid valve 304.
[0029] During operation, the first pressure sensor 501 transmits the pressure signal detected, the pressure signal detected by the second pressure sensor 502, the liquid level signal detected by the first liquid level sensor 401, and the liquid level signal detected by the second liquid level sensor 402 to the control system. The control system processes the received pressure and liquid level signals and controls the opening and closing of the negative pressure pump 201 and the liquid displacement pump 301, as well as the opening and closing of the first solenoid valve 206, the second solenoid valve 207, the third solenoid valve 204, and the fourth solenoid valve 304 according to the processed data. The liquid displacement method is:
[0030] (1) Establishing a negative pressure system: The control system controls the first solenoid valve 206 and the third solenoid valve 204 to be powered off so that the negative pressure pipeline is in a pass state, starts the negative pressure pump 201 to extract negative pressure, and powers off the second solenoid valve 207 and the fourth solenoid valve 304, so that the pressure of the negative pressure energy storage container 202 ≥ the pressure of the pressure reducing valve 205 ≥ the pressure of the waste liquid storage container 203 > the relative environment of the cleaning container 100;
[0031] (2) Liquid extraction: When neither the first liquid level sensor 401 nor the second liquid level sensor 402 gives an alarm (i.e., the liquid levels in the negative pressure energy storage container 202 and the waste liquid storage container 203 are within the preset range), the second solenoid valve 207 is opened, and the liquid in the cleaning container 100 enters the waste liquid storage container 203 under the action of negative pressure;
[0032] During the liquid extraction process, if the pressure in the negative pressure system (1) established meets the liquid extraction demand, the negative pressure pump 201 is in a non-working state; and during this process, if the pressure of the waste liquid storage container 203 is relatively low, the pressure of the waste liquid storage container 203 can be compensated by the negative pressure energy storage container 202 by opening and closing the pressure reducing valve 205, thereby adjusting the negative pressure of the negative pressure liquid extraction system;
[0033] When the negative pressure provided by the negative pressure energy storage container 202 cannot meet the liquid extraction requirement, repeat step (1) to establish the negative pressure system again;
[0034] (3) Liquid drainage: When the second liquid level sensor 402 sounds an alarm, the second solenoid valve 207 is disconnected, the first solenoid valve 206 is powered on and disconnected, and the control system sends a start command to the liquid drainage pump 301. The liquid drainage pump 301 starts, and the fourth solenoid valve 304 on the liquid drainage branch pipe 303.2 is powered on. The liquid drainage pump 301 discharges the waste liquid in the waste liquid storage container 203 into the designated recovery container;
[0035] When the first liquid level sensor 401 generates a water level alarm, ensure that the negative pressure pump 201 is in a stopped state, the third solenoid valve 204 is powered on and off, the liquid discharge pump 301 is started, both fourth solenoid valves 304 are powered on and the second solenoid valve 207 is powered off, and the waste liquid in the negative pressure energy storage container 202 and the waste liquid storage container 203 is discharged into the designated recovery container.
[0036] The present invention establishes a negative pressure system and utilizes negative pressure to quickly extract the waste liquid in the cleaning container 100 into the waste liquid storage container 203. At the same time, the negative pressure energy storage container 202 can also compensate for the negative pressure of the waste liquid storage container 203, further ensuring that the negative pressure system can extract the waste liquid in the cleaning container 100 into the waste liquid storage container 203 and the negative pressure energy storage container 202, thereby achieving rapid and complete extraction of waste liquid, effectively avoiding the outer wall of the sampling needle from sticking to the wall, further avoiding cross contamination, and improving reliability.
[0037] It should be noted that all directional indications (such as up, down, left, right, front, back, etc.) in the embodiments of the present invention are only used to explain the direction of the object in a specific posture (such as the attached image). Figure 1 The relative positional relationship and movement conditions between the components (as shown) under the directional indication are as follows. If the specific posture changes, the directional indication will also change accordingly. In the present invention, unless otherwise clearly specified and limited, the terms "connection" and "fixed" should be understood in a broad sense. For example, "fixed" can be a fixed connection, a detachable connection, or an integral whole; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to the specific circumstances.
[0038] In addition, in the present invention, descriptions such as "first", "second", etc. are only used for descriptive purposes and cannot be understood as indicating or implying their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In addition, the meaning of "and / or" appearing throughout the text is to include three parallel solutions. Taking "A and / or B as an example", it includes solution A, or solution B, or solutions that meet both A and B. In addition, the technical solutions between the various embodiments can be combined with each other, but they must be based on the ability of ordinary technicians in this field to implement them. When the combination of technical solutions is mutually contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by the present invention.
Claims
1. A waste liquid discharge system for a chemiluminescence analyzer, characterized in that: It includes a negative pressure liquid pumping system connected to the cleaning container and a liquid discharge system connected to the negative pressure liquid pumping system; The negative pressure liquid extraction system includes a negative pressure pump, a negative pressure energy storage container and a waste liquid storage container which are sequentially connected through a negative pressure pipeline, and the liquid inlet of the negative pressure pipeline is connected to the liquid discharge port of the cleaning container; a first solenoid valve and a pressure reducing valve are arranged at intervals on the negative pressure pipeline between the negative pressure energy storage container and the waste liquid storage container, and a second solenoid valve is arranged on the negative pressure pipeline between the waste liquid storage container and the cleaning container; A third solenoid valve is provided on the negative pressure pipeline between the negative pressure energy storage container and the negative pressure pump; The pressure of the negative pressure energy storage container ≥ the pressure of the pressure reducing valve ≥ the pressure of the waste liquid storage container > the pressure of the cleaning container; a first liquid level sensor and a first pressure sensor are provided in the negative pressure energy storage container, and a second liquid level sensor and a second pressure sensor are provided in the waste liquid storage container.
2. The waste liquid discharge system for a chemiluminescence analyzer according to claim 1, characterized in that: There is at least one negative pressure energy storage container.
3. The waste liquid discharge system for a chemiluminescence analyzer according to claim 1, characterized in that: The drainage system includes a drainage pump and a drainage pipeline. The inlet of the drainage pipeline is connected to the negative pressure energy storage container and the waste liquid storage container respectively, and the outlet thereof is connected to the inlet of the drainage pump.
4. The waste liquid discharge system for a chemiluminescence analyzer according to claim 3, characterized in that: The drainage pipeline includes a drainage main pipe connected to the drainage pump and two drainage branches connected to the drainage main pipe, and each of the drainage branches is provided with a fourth solenoid valve.
5. The waste liquid discharge system for a chemiluminescence analyzer according to claim 4, characterized in that: The first solenoid valve and the third solenoid valve are both two-position three-way solenoid valves, and the second solenoid valve and the fourth solenoid valve are both two-way solenoid valves.
6. The waste liquid discharge system for a chemiluminescence analyzer according to claim 5, characterized in that: The first solenoid valve and the third solenoid valve are normally open two-position three-way solenoid valves.
Citation Information
Patent Citations
Negative pressure waste liquid system, biochemical analyzer, and waste liquid discharge method
CN104111326A
Vacuum negative pressure system with automatic drainage function
CN210099565U
The system is used for waste liquid discharge system of chemiluminescence analyzer
CN212568822U