A biological cell staining machine

Abstract

The present invention provides a biological cell staining machine, comprising: a vertical guide rail, a clutch connecting member two with one end connected to a lifting device and the other end connected to a hanging basket fixing device; a shock absorber or the impact rod with one end fixedly connected to the vertical guide rail and the other connected to the hanging basket fixing device. In the biological cell staining machine provided by the present invention, when the clutch connecting member two is in a closed state, the hanging basket fixing device is fixed on the lifting device. When the clutch connecting member two is in a separated state, the hanging basket fixing device makes a free fall along the vertical guide rail, and the shock absorber and the impact rod collide with each other. The speed of the hanging basket fixing device drops to zero within a very short time, generating a huge acceleration to shake off the residual liquid attached to the hanging basket and the glass slide, effectively solving the problem of residual liquid pollution caused when the hanging basket is transferred from one reagent cylinder to another reagent cylinder.

Description

Technical Field

[0001] The present invention relates to the technical field of biological cell staining, and particularly to a biological cell staining machine. Background Art

[0002] During the cell staining process, multiple reagents need to be processed, and the glass slide needs to be transferred multiple times from one reagent tank to another. Therefore, multiple reagent tanks are arranged under the robotic arm in the hanging basket type staining machine. However, after the hanging basket is taken out of the reagent tank, a large amount of reagent adheres to the hanging basket and the glass slide to form residual liquid. If it is directly moved into the next reagent tank, it will inevitably cause relatively serious contamination to the reagent in the next reagent tank. In order to extend the service life of the reagent as much as possible, after the hanging basket is taken out of the reagent tank, the reagent adhering to the hanging basket or the glass slide needs to be removed. Summary of the Invention

[0003] The present invention aims to solve at least one of the technical problems existing in the prior art. For this purpose, the present invention provides a biological cell staining machine, including:

[0004] A frame (1),

[0005] A vertical guide rail (52) vertically arranged on the frame (1),

[0006] A hanging basket fixing device (62) movably arranged on the vertical guide rail (52),

[0007] A lifting device for lifting the hanging basket fixing device to the upper part of the vertical guide rail;

[0008] A second clutch connecting member, one end of which is connected to the lifting device and the other end is connected to the hanging basket fixing device (62);

[0009] A shock absorber (55) and an impact rod (64), one of the shock absorber and the impact rod is fixedly connected to the vertical guide rail (52), and the other is connected to the hanging basket fixing device (62) to keep synchronous in the horizontal position.

[0010] Further, the second clutch connecting member includes an electromagnetic chuck two (72) and a ferromagnetic body two (82), one of the electromagnetic chuck two (72) and the ferromagnetic body two (82) is connected to the lifting device, and the other is connected to the hanging basket fixing device to keep synchronous in the horizontal position.

[0011] Further, the lifting device includes a first slider (53) disposed on the vertical guide rail (52), and a power device connected to the first slider. The first slider (53) is connected to one of the second electromagnetic chuck (72) and the second ferromagnetic body (82).

[0012] Further, it further includes a second slider (54) disposed on the vertical guide rail (52) and below the first slider. The hanging basket fixing device (62) is synchronously connected to the second slider (54) in the horizontal position. One of the second electromagnetic chuck (72) and the second ferromagnetic body (82) is fixedly connected to the second slider (54), and the other is fixedly connected to the first slider (53).

[0013] Further, it further includes a longitudinal guide rail (6) and a third slider (61). The hanging basket fixing device (62) is disposed on the third slider. The third slider is disposed on the longitudinal guide rail, and the longitudinal guide rail is horizontally disposed on the second slider.

[0014] Further, the second electromagnetic chuck (72) is preferably a power-off type electromagnetic chuck.

[0015] Further, it further includes a positioning device fixedly disposed on the upper part of the vertical guide rail and above the lifting device. The positioning device is a first clutch connecting member, one end of which is fixedly connected to the upper part of the vertical guide rail, and the other end is connected to the lifting device.

[0016] Further, the first clutch connecting member includes a first electromagnetic chuck (71) and a first ferromagnetic body (81). One of the first electromagnetic chuck (71) and the first ferromagnetic body (81) is disposed on the upper part of the vertical guide rail, and the other is connected to the lifting device.

[0017] Further, a support frame (51) is provided at the top of the vertical guide rail. One of the first electromagnetic chuck (71) and the first ferromagnetic body (81) is disposed on the support frame.

[0018] Further, the first electromagnetic chuck (71) is preferably a power-off type electromagnetic chuck.

[0019] Further, it further includes a transverse guide rail (4) and a vertical support plate (5). The transverse guide rail is disposed on the frame (1); the vertical support plate (5) is disposed on the transverse guide rail (4); the vertical guide rail is disposed on the vertical support plate.

[0020] Further, it further includes a telescopic electromagnet, and the impact rod is connected to the telescopic electromagnet.

[0021] A biological cell staining machine provided by the present invention is provided with a second clutch connecting member between the lifting device and the hanging basket fixing device. When the second clutch connecting member is in a closed state, the hanging basket fixing device is fixed on the lifting device. When the second clutch connecting member is in a separated state, the hanging basket fixing device moves in free fall along the vertical guide rail. When the shock absorber and the impact rod connected to the vertical guide rail and the hanging basket fixing device collide with each other, the speed of the hanging basket fixing device drops to zero in a very short time, generating a huge acceleration, so as to shake off the residual liquid attached to the hanging basket and the glass slide, effectively solving the problem of residual liquid pollution caused when the hanging basket is transferred from one reagent cylinder to another. When the staining is completed, the lifting device lifts the hanging basket fixing device to the upper part of the vertical guide rail and is fixed by the positioning device. Since a power-off type electromagnetic chuck is adopted, the hanging basket fixing device will not be affected by power-off after being fixed to the upper part of the vertical guide rail, improving the safety of the equipment during operation and storage. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 is a schematic structural diagram of a biological cell staining machine provided by the present invention;

[0023] Among them, 1, frame; 2, reagent cylinder; 3, hanging basket; 4, horizontal guide rail; 5, vertical support plate; 51, support frame; 52, vertical guide rail; 53, slider one; 54, slider two; 55, shock absorber; 6, longitudinal guide rail; 61, slider three; 62, hanging basket fixing device; 63, telescopic electromagnet; 64, impact rod; 71, electromagnetic chuck one; 72, electromagnetic chuck two; 81, ferromagnetic body one; 82, ferromagnetic body two. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0024] The embodiments of the present invention will be described in detail below. The examples of the embodiments are shown in the drawings, where the same or similar reference numerals represent the same or similar elements or elements with the same or similar functions from beginning to end. The embodiments described below with reference to the drawings are exemplary and are only used to explain the present invention and should not be construed as a limitation of the present invention.

[0025] In the description of the present invention, it should be understood that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present invention.

[0026] In the description of the present invention, it should be noted that unless otherwise clearly specified and defined, the terms "installation", "connection", and "setting" should be understood in a broad sense. For example, it can be fixedly connected and set, or detachably connected and set, or integrally connected and set. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0027] As Figure 1 shown, the present invention provides a biological cell staining machine, comprising:

[0028] a frame 1,

[0029] a horizontal guide rail 4 is arranged on the frame 1, and a vertical support plate 5 is arranged on the horizontal guide rail.

[0030] a vertical guide rail 52, the vertical guide rail is arranged on the vertical support plate, and a first slider 53 and a second slider 54 are arranged on the vertical guide rail. The first slider 53 is located above the second slider 54.

[0031] a longitudinal guide rail 6, the longitudinal guide rail is horizontally and fixedly arranged on the second slider, and a third slider 61 is arranged on the longitudinal guide rail.

[0032] a hanging basket fixing device 62. In this embodiment, the hanging basket fixing device 62 is arranged on the third slider. In some other embodiments without the longitudinal guide rail 6, the hanging basket fixing device is directly movably arranged on the vertical guide rail 52, that is, the hanging basket fixing device is directly fixedly connected to the second slider.

[0033] a lifting device, the lifting device is used to lift the hanging basket fixing device to the upper part of the vertical guide rail; the lifting device includes a power device arranged on the first slider 53 and connected to the first slider. Here, the power device can be a motor and a toothed belt connected to the motor. The motor drives the toothed belt, and the toothed belt drives the first slider to rise or fall.

[0034] a second clutch connecting member, one end of the second clutch connecting member is connected to the lifting device, and the other end is connected to the hanging basket fixing device 62; the second clutch connecting member includes an electromagnetic chuck two 72 and a ferromagnetic body two 82. One of the electromagnetic chuck two 72 and the ferromagnetic body two 82 is connected to the lifting device, that is, fixedly connected to the first slider 53, and the other is fixedly connected to the second slider 54, that is, connected to the hanging basket fixing device to keep synchronous in the horizontal position, so as to achieve the effect of lifting the hanging basket.

[0035] A shock absorber 55 and an impact rod 64, one of the shock absorber and the impact rod is fixedly connected to the vertical guide rail 52, and the other can be arranged on the second slider 54 or the longitudinal guide rail 6 or directly arranged on the hanging basket fixing device 62, and its purpose is to be synchronously connected with the hanging basket fixing device 62 in the horizontal position. It also includes a telescopic electromagnet 63, the impact rod is connected to the telescopic electromagnet, and the telescopic electromagnet can drive the impact rod to extend forward or retract.

[0036] Furthermore, it also includes a positioning device fixedly arranged on the upper part of the vertical guide rail and above the lifting device. The positioning device is a first clutch connecting member, one end of which is fixedly connected to the upper part of the vertical guide rail, and the other end is connected to the lifting device. The first clutch connecting member includes an electromagnetic chuck 71 and a ferromagnetic body 81. One of the electromagnetic chuck 71 and the ferromagnetic body 81 is arranged on the upper part of the vertical guide rail, and the other is connected to the lifting device. A support frame 51 can also be arranged at the top of the vertical guide rail, and one of the electromagnetic chuck 71 and the ferromagnetic body 81 is arranged on the support frame.

[0037] It should be noted that in the present invention, the first ferromagnetic body and the second ferromagnetic body can both be made of materials such as iron, cobalt, nickel and their alloys, and ferrite that can be attracted by a magnet. The electromagnetic chucks are preferably power-off type electromagnetic chucks. The structure of the power-off type electromagnetic chuck includes a permanent magnet and an electromagnet. In the energized state, the electromagnet generates a magnetic field to cancel the magnetic field of the permanent magnet, and in the power-off state, since the electromagnet does not produce any effect, the permanent magnet exhibits the existing magnetic force to attract the ferromagnetic body. In the first clutch connecting member, the positions of the electromagnetic chuck 71 and the ferromagnetic body 81 can be interchanged. Similarly, in the second clutch connecting member, the positions of the electromagnetic chuck 72 and the ferromagnetic body 82 can also be interchanged.

[0038] The working principle of the present invention is as follows:

[0039] 1. Before the power-on state, both the electromagnetic chuck and the second electromagnetic chuck are in the power-off state;

[0040] 2. After power-on, the first electromagnetic chuck is energized, the second electromagnetic chuck remains power-off, the first clutch connecting member separates, the second clutch connecting member closes, the first slider and the second slider are fixedly connected and slide down under the drive of the motor of the lifting device, and at the same time, the longitudinal slider three is moved, and the hanging basket fixing device 62 grabs the hanging basket 3; the lifting device lifts the first slider to the upper part of the vertical guide rail;

[0041] 3. The second electromagnetic chuck is energized, the second clutch connecting member separates, the first slider is separated from the second slider, and the second slider, the longitudinal track and the hanging basket fixing device fall freely downward;

[0042] 4. The telescopic electromagnet is energized, and the impact rod extends; the impact rod collides with the shock absorber, the speed of the hanging basket decreases sharply to zero, generating a huge acceleration, and the residual liquid on the hanging basket and the glass slide is shaken off and removed;

[0043] 5. The lifting device also descends subsequently when the second slider is in free fall. After the impact rod collides with the shock absorber, the lifting device catches up with the second slider, the second electromagnetic chuck contacts and adsorbs with the second ferromagnetic body, the second clutch connecting piece closes, the motor moves upward in the reverse direction, the second slider follows the first slider and moves upward, and at the same time, the longitudinal slider three is moved to align the hanging basket with the next working station and the motor moves downward in the reverse direction again to place the hanging basket into the reagent tank 2;

[0044] 6. When the motor moves upward in the reverse direction to the upper part of the vertical guide rail, the first electromagnetic chuck loses power, and the first electromagnetic chuck has magnetic force to adsorb the first ferromagnetic body arranged on the lifting device, and the first clutch connecting piece closes, thus completing the positioning operation.

[0045] Although the embodiments of the present invention have been shown and described, those of ordinary skill in the art can understand that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present invention. The scope of the present invention is defined by the claims and their equivalents.

Claims

1. A biological cell staining machine, characterized in that, Comprising: A frame (1), Vertical guide rails (52), which are vertically arranged on the frame (1), A hanging basket fixing device (62), which is movably arranged on the vertical guide rails (52), A lifting device for lifting the hanging basket fixing device to the upper part of the vertical guide rails; A second clutch connecting member, one end of which is connected to the lifting device and the other end is connected to the hanging basket fixing device (62); A shock absorber (55) and an impact rod (64), one of the shock absorber and the impact rod is fixedly connected to the vertical guide rails (52), and the other is connected to the hanging basket fixing device (62) to keep in synchronization in the horizontal position. The second clutch connecting member includes an electromagnetic chuck two (72) and a ferromagnetic body two (82), one of the electromagnetic chuck two (72) and the ferromagnetic body two (82) is connected to the lifting device, and the other is connected to the hanging basket fixing device to keep in synchronization in the horizontal position; It further includes a positioning device fixedly arranged at the upper part of the vertical guide rails and above the lifting device. The positioning device is a first clutch connecting member, one end of which is fixedly connected to the upper part of the vertical guide rails and the other end is connected to the lifting device.

2. The biological cell staining machine according to claim 1, wherein, The lifting device includes a first slider (53) arranged on the vertical guide rails (52) and a power device connected to the first slider. The first slider (53) is connected to one of the electromagnetic chuck two (72) and the ferromagnetic body two (82).

3. The biological cell staining machine according to claim 2, wherein, It further includes a second slider (54) arranged on the vertical guide rails (52) and below the first slider. The hanging basket fixing device (62) is connected to the second slider (54) to keep in synchronization in the horizontal position. One of the electromagnetic chuck two (72) or the ferromagnetic body two (82) is fixedly connected to the second slider (54), and the other is fixedly connected to the first slider (53).

4. The biological cell staining machine according to claim 3, characterized in that, It further includes a longitudinal guide rail (6) and a third slider (61). The hanging basket fixing device (62) is arranged on the third slider, the third slider is arranged on the longitudinal guide rail, and the longitudinal guide rail is horizontally arranged on the second slider.

5. The biological cell staining machine according to any one of claims 2-4, characterized in that, The electromagnetic chuck two (72) is a power-off type electromagnetic chuck.

6. The biological cell staining machine according to claim 1, characterized in that, The first clutch connecting member includes an electromagnetic chuck one (71) and a ferromagnetic body one (81), one of the electromagnetic chuck one (71) and the ferromagnetic body one (81) is arranged at the upper part of the vertical guide rails, and the other is connected to the lifting device.

7. The biological cell staining machine according to claim 6, characterized in that, A support frame (51) is arranged at the top of the vertical guide rails, and one of the electromagnetic chuck one (71) and the ferromagnetic body one (81) is arranged on the support frame.

8. The biological cell staining machine according to any one of claims 6-7, characterized in that, The electromagnetic chuck one (71) is a power-off type electromagnetic chuck.

9. The biological cell staining machine according to claim 1, wherein, It further includes a transverse guide rail (4) and a vertical support plate (5). The transverse guide rail is arranged on the frame (1); the vertical support plate (5) is arranged on the transverse guide rail (4); the vertical guide rails are arranged on the vertical support plate.

10. The biological cell staining machine according to claim 1, wherein, It further includes a telescopic electromagnet, and the impact rod is connected to the telescopic electromagnet.

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