A multifunctional sampling and injection device and a detection device and method having the same

Abstract

The present invention provides a multifunctional sampling and injection device and a detection device and method having the device, the device comprises: a guiding structure, an analysis port, an analysis chamber, an osmotic chamber, a storage chamber, a first carrier gas path and a first injection pipeline, the analysis port is connected to the guiding structure, the analysis chamber is respectively connected to the analysis port and the air extraction port, the output end of the air extraction port is connected to the suction pump, the osmotic chamber is separated from the analysis chamber by a semipermeable membrane, and the two ends thereof are respectively connected with an air inlet and an air outlet, the carrier gas is mixed with the sample to be tested through the first carrier gas path and then injected; it also comprises a quantitative sampling path and a second injection path, the quantitative sampling path comprises a quantitative loop and a sampling pump, the second injection path comprises a second carrier gas path and a second injection pipeline, the carrier gas is mixed with the sample to be tested in the quantitative loop through the second carrier gas path and injected. The device in the present invention can perform qualitative or quantitative sampling and injection for multi-morphological samples, greatly improving the field applicability and application range of the detection equipment.

Description

Technical Field

[0001] The present invention relates to the field of micro / trace analysis detection technology and security inspection technology, and in particular to a multifunctional sampling and injection device and a detection device and method having the device. Background Art

[0002] Portable gas chromatographs, ion mobility spectrometers, mass spectrometers and their combined devices have the characteristics of sensitive, rapid detection and reliable results. These instruments are widely used in on-site in-situ inspection fields such as chemical defense, drug control, security inspection, bomb disposal, environmental monitoring, toxic gas monitoring, fire monitoring, water pollution monitoring, respiratory disease screening and rapid food monitoring.

[0003] A portable gas chromatograph is mainly composed of an inlet, a chromatographic column, a chromatographic carrier gas and gas path system, a temperature control system and a chromatographic detector. The sampling method generally adopts the injection method, which can conveniently analyze and detect gas samples, but it is difficult to complete the sampling and detection of solid samples.

[0004] The ion mobility spectrometer is mainly composed of an inlet, an ionization source, a migration tube assembly and a Faraday cup. For different application scenarios, the ion mobility spectrometer is usually equipped with different sampling and inlet ports. In the existing technology, wipe sampling thermal desorption, spot sampling thermal desorption and direct inhalation penetration sampling are mainly used, which are more suitable for sampling and detection of gases, powders and liquids, but it is difficult to achieve sampling and detection of non-volatile solid samples.

[0005] The portable mass spectrometer system is mainly composed of a sampling system, a vacuum system, an ionization source, a mass analyzer and a mass spectrometer detector. At present, diffusion sampling is used for pure compounds involving gases or volatile liquids, and probe sampling is used for pure compounds involving non-volatile liquids or solids. For mixtures with more complex components, the sample needs to be separated into single components before sampling. It can be seen that the sampling device is an essential structural component of this type of analytical detection instrument.

[0006] Different forms of sampling and injection methods are often required for different physical forms of samples to be tested. For gas samples, sampling and injection are mainly carried out by pumping gas; for liquid samples, injection or spot sampling or wiping adsorption followed by thermal desorption is usually used for injection; for solid samples, solid samples are mostly injected after heating and vaporization. Most existing commercial instruments only provide a single solid, liquid or gas injection device, and there are few multifunctional sampling and injection devices for samples of multiple physical forms. To measure samples of different physical forms, either the injection device must be replaced, or only samples of a single form, such as gas, liquid or solid, can be measured. Moreover, the sampling and injection volume of these sampling and injection devices cannot be controlled during the sampling and injection process, which limits some application requirements that require precise quantitative analysis, thereby limiting the on-site application of such instruments.

[0007] Therefore, it is necessary to provide an improved technical solution to address the above-mentioned deficiencies in the prior art. Summary of the invention

[0008] In view of the shortcomings of the prior art described above, the purpose of the present invention is to provide a multifunctional sampling and injection device and a detection equipment and method having the device, so as to solve the problem that the detection equipment in the prior art only provides a single solid, liquid or gas sampling and injection device, which limits its field applicability and application scope, and the sampling and injection amount of the sampling and injection device cannot be controlled during the sampling and injection process, and quantitative analysis of the samples to be detected cannot be achieved.

[0009] In order to achieve the above-mentioned purpose and other related purposes, the present invention provides a multifunctional sampling and injection device. The multifunctional sampling and injection device comprises:

[0010] A guide structure, wherein the guide structure is used to introduce a sample to be tested;

[0011] A parsing unit, the parsing unit comprising a parsing port, a parsing cavity, a permeation cavity and a storage cavity;

[0012] Wherein, the input end of the analysis port is sealed and connected to the guide structure;

[0013] One end of the analysis chamber is connected to the output end of the analysis port, and the other end is connected to the input end of the air suction port. The output end of the air suction port is connected to an air suction pump. The sample to be tested enters the analysis port and the analysis chamber in sequence from the guide structure under the negative pressure of the air suction pump.

[0014] The osmotic chamber is separated from the analytical chamber by a semipermeable membrane, and part of the sample to be tested in the analytical chamber permeates into the osmotic chamber through the semipermeable membrane, and both ends of the osmotic chamber are respectively connected with an air inlet and an air outlet through a pipeline; the storage chamber is located below the osmotic chamber and is connected to the osmotic chamber through a volatilization pipeline, and the storage chamber is used to collect and place samples, and the volatilized sample to be tested enters the osmotic chamber through the volatilization pipeline;

[0015] The gas circuit system comprises a first sampling gas circuit, the first sampling gas circuit comprises a first carrier gas circuit and a first sampling pipeline, the first carrier gas circuit comprises a carrier gas interface and a first carrier gas pipeline, one end of the first carrier gas pipeline is connected to the carrier gas interface, and the other end is connected to the air inlet; the first sampling pipeline is connected to the permeation cavity through the air outlet, the carrier gas enters the permeation cavity through the air inlet and mixes with the sample to be tested into a mixed gas, and the mixed gas is sampled through the air outlet and the first sampling pipeline in sequence.

[0016] Preferably, the gas circuit system further comprises a quantitative sampling gas circuit and a second sampling gas circuit;

[0017] The quantitative sampling gas circuit includes a quantitative ring and a sampling pump, wherein the two ends of the quantitative ring are connected to the gas outlet and the sampling pump respectively through a control valve, and the sampling pump collects the sample to be tested in the permeation cavity into the quantitative ring;

[0018] The second sampling gas circuit includes a second carrier gas circuit and a second sampling pipeline, the second carrier gas circuit includes a carrier gas interface and a second carrier gas pipeline, one end of the second carrier gas pipeline is connected to the carrier gas interface, and the other end is connected to the quantitative loop through a control valve, the carrier gas enters the quantitative loop and mixes with the sample to be tested to form a quantitative mixed gas; the second sampling pipeline is connected to the quantitative loop through a control valve, and the quantitative mixed gas is sampled through the second sampling pipeline.

[0019] Preferably, the control valve is a six-way valve. Preferably, a positioning top bead is provided on the analytical port, a guide structure is provided at the rear end of the guide structure, a positioning groove is provided on the guide structure, and the positioning groove is matched and connected with the positioning top bead;

[0020] A sealing ring is provided at the front end of the guide structure, and the sealing ring is used for sealing between the guide structure and the analysis port;

[0021] The guide structure is made of PTFE or PEEK material.

[0022] Preferably, a sampling head is detachably connected to the front end of the guide structure.

[0023] Preferably, the analysis port and the analysis cavity are both provided with a heating device, and a heat preservation sleeve is provided on the periphery thereof;

[0024] The analysis port and the analysis cavity are both made of red copper with good thermal conductivity.

[0025] Preferably, an air guide platform is provided in the osmotic chamber, the air guide platform is located below the semipermeable membrane, and a vortex flow channel is formed between the air guide platform and the semipermeable membrane;

[0026] A mesh fixing sheet is also provided on the upper surface of the semipermeable membrane, and the mesh fixing sheet is used to fix the semipermeable membrane.

[0027] Preferably, a sample box is placed in the storage cavity, a volatilization hole is opened on the sample box, the volatilization hole is connected with the permeation cavity through a volatilization pipeline, and the volatilized sample to be tested enters the permeation cavity through the volatilization hole;

[0028] A semipermeable membrane is attached to the top of the sample box.

[0029] Preferably, a heating lifting platform is provided at the bottom of the sample box, and the heating lifting platform is used to position and lift the sample box;

[0030] A sealing ring is arranged on the upper surface of the heating lifting platform.

[0031] The present invention also provides a detection device, the detection device comprising:

[0032] The multifunctional sampling and injection device as described in any one of the above; and

[0033] The detection unit includes a gas chromatography system, an ion mobility spectrometry system, a mass spectrometry system and a combination thereof, and the injection output end of the multifunctional sampling and injection device is respectively connected to the injection input end of the gas chromatography system, the ion mobility spectrometry system, the mass spectrometry system and a combination thereof.

[0034] The present invention also provides a detection method, which uses the above detection device to detect the sample to be detected.

[0035] As described above, the multifunctional sampling and injection device of the present invention and the detection equipment and method having the same have the following beneficial effects:

[0036] The multifunctional sampling and injection device of the present invention comprises a guiding structure, an analysis port, an analysis chamber, an osmotic chamber, a first carrier gas path and a first injection gas path, wherein the guiding structure is connected to the input end of the analysis port and is used to introduce a gaseous sample to be tested. Since the osmotic chamber and the analysis chamber are separated only by a semipermeable membrane, a part of the sample to be tested that enters the analysis chamber passes through the semipermeable membrane into the osmotic chamber to complete sampling. At the same time, the carrier gas enters the osmotic chamber and mixes with the sample to be tested to form a mixed gas. The mixed gas is injected through the first injection pipe, thereby realizing the sampling and injection of the gaseous sample by the device. The device of the present invention is also provided with a storage chamber, which stores The solid or liquid sample stored in the storage cavity is volatilized by heating, and the volatilized sample to be tested enters the permeation cavity through the volatilization pipeline to complete sampling. The sample to be tested is then mixed with the carrier gas to form a mixed gas, and the mixed gas is sampled through the first sampling pipeline, thereby realizing the sampling and injection of solid and liquid samples by the device; that is, the multifunctional sampling and injection device in the present invention can sample and inject gas, liquid and solid at the same time, and the detection equipment in the present invention includes the multifunctional sampling and injection device and the detection unit. When the detection equipment with the multifunctional sampling and injection device detects the sample to be tested, its on-site applicability is greatly improved.

[0037] The multifunctional sampling and injection device of the present invention is also provided with a quantitative sampling gas circuit and a second sampling gas circuit. The quantitative sampling gas circuit includes a quantitative ring and a sampling pump. The sample to be tested entering the permeation cavity is quantitatively collected into the quantitative ring through the sampling pump; the second sampling gas circuit includes a second carrier gas circuit and a second sampling pipeline. The carrier gas enters the quantitative ring through the second carrier gas circuit and mixes with the sample to be tested in the quantitative ring to form a quantitative mixed gas, and then the quantitative mixed gas is injected through the second sampling gas circuit, thereby realizing quantitative sampling and injection of the sample to be tested. That is, the multifunctional sampling and injection device of the present invention can quantitatively sample and inject the target sample, and the detection equipment with the multifunctional sampling and injection device can realize the controllable sampling and injection amount of the target sample, thereby meeting the precise quantitative analysis of the sample to be tested, such as rapid screening of the target sample and concentration analysis of the target substance, which greatly improves the application range of the detection equipment. BRIEF DESCRIPTION OF THE DRAWINGS

[0038] Figure 1 Shown is a structural schematic diagram of a guiding structure in an embodiment of the present invention.

[0039] Figure 2 Shown is a structural schematic diagram of another guiding structure in an embodiment of the present invention.

[0040] Figure 3 Shown is a schematic cross-sectional structure diagram of an analysis unit in an embodiment of the present invention.

[0041] Figure 4 Shown is a schematic diagram of the top view structure of the analysis unit in an embodiment of the present invention.

[0042] Figure 5 Shown is a bottom-up structural schematic diagram of the analysis unit in an embodiment of the present invention.

[0043] Figure 6 It shows a schematic diagram of the gas path connection of a detection device with a multifunctional sampling and injection device in an embodiment of the present invention.

[0044] Figure 7 Shown is a schematic diagram of the gas path connection when the detection device in an embodiment of the present invention performs quantitative sampling.

[0045] Figure 8 It shows a schematic diagram of gas path connection when the detection device switches to the quantitative injection state after completing the quantitative sampling in an embodiment of the present invention.

[0046] Fig. 9 It shows a schematic diagram of gas path connection when the detection device in the embodiment of the present invention is in the qualitative sampling and injection state.

[0047] Component number description

[0048] 101-11 Analysis port

[0049] 101-12 Positioning bead

[0050] 101-21 Analysis chamber

[0051] 101-22 Air extraction port

[0052] 101-23 Insulation Cover

[0053] 101-31 Infiltration Chamber

[0054] 101-32 Semipermeable membrane

[0055] 101-33 Mesh fixing sheet

[0056] 101-34 Air Inlet

[0057] 101-35 Air outlet

[0058] 101-36 Gas table

[0059] 101-41 Sample Box

[0060] 101-42 Volatile pores

[0061] 101-43 Semipermeable membrane

[0062] 101-51 Heating lift table

[0063] 101-52 Sealing ring

[0064] 201-A-1 Boot Structure

[0065] 201-B-1 Boot Structure

[0066] 201-1 Sealing ring

[0067] 201-2 Positioning groove

[0068] 201-3 Sampling head

[0069] 301-11 First and second position three-way valve

[0070] 301-12 Second two-position three-way valve

[0071] 301-13 3 / 2-position 3-way valve

[0072] 301-2 Three-way valve

[0073] 301-3 Six-way valve

[0074] 301-4 Carrier gas interface

[0075] 301-5 First carrier gas pipeline

[0076] 301-6 Quantitative ring

[0077] 301-7 Second carrier gas pipeline DETAILED DESCRIPTION

[0078] The following describes the embodiments of the present invention through specific examples, and those skilled in the art can easily understand other advantages and effects of the present invention from the contents disclosed in this specification. The present invention can also be implemented or applied through other different specific embodiments, and the details in this specification can also be modified or changed in various ways based on different viewpoints and applications without departing from the spirit of the present invention.

[0079] For example, when describing the embodiments of the present invention in detail, for the sake of convenience, the cross-sectional view showing the device structure will not be partially enlarged according to the general scale, and the schematic view is only an example, which should not limit the scope of protection of the present invention. In addition, in actual production, the three-dimensional space dimensions of length, width and depth should be included.

[0080] For ease of description, spatially relative terms such as "under", "below", "below", "below", "above", "on", etc. may be used herein to describe the relationship of one element or feature shown in the drawings to other elements or features. It will be understood that these spatially relative terms are intended to encompass other orientations of the device in use or operation in addition to the orientation depicted in the drawings. In addition, when a layer is referred to as being "between" two layers, it can be the only layer between the two layers, or one or more intervening layers may also be present.

[0081] In the context of the present application, a structure in which a first feature is described as being "above" a second feature may include embodiments in which the first and second features are formed in direct contact, and may also include embodiments in which additional features are formed between the first and second features, such that the first and second features may not be in direct contact.

[0082] It should be noted that the illustrations provided in this embodiment are only used to schematically illustrate the basic concept of the present invention. Therefore, the drawings only show components related to the present invention rather than being drawn according to the number, shape and size of components in actual implementation. In actual implementation, the type, quantity and proportion of each component may be changed arbitrarily, and the component layout may also be more complicated.

[0083] There are few multifunctional sampling and injection devices for various forms of samples to be tested in the prior art. When measuring samples of different forms, either the sampling and injection devices must be replaced, or only samples of a single form can be measured, which limits the field application of this type of device. In addition, the sampling and injection volumes of these sampling and injection devices are uncontrollable during the sampling and injection process, making it impossible to achieve quantitative analysis of the samples to be tested.

[0084] See also Figures 1 to 9 The multifunctional sampling and injection device of the present invention comprises a guiding structure, an analysis port, an analysis chamber, an osmotic chamber, a first carrier gas path and a first injection gas path, wherein the guiding structure is connected to the input end of the analysis port and is used to introduce a gaseous sample to be tested. Since the osmotic chamber and the analysis chamber are separated only by a semipermeable membrane, a part of the sample to be tested that enters the analysis chamber passes through the semipermeable membrane into the osmotic chamber to complete sampling. At the same time, the carrier gas enters the osmotic chamber and mixes with the sample to be tested to form a mixed gas. The mixed gas is injected through the first injection pipe, thereby realizing the sampling and injection of the gaseous sample by the device. The device of the present invention is also provided with a storage chamber. The solid or liquid sample stored in the storage chamber is volatilized by heating, and the volatilized sample to be tested enters the permeation chamber through the volatilization pipe to complete sampling. The sample to be tested is then mixed with the carrier gas to form a mixed gas, and the mixed gas is sampled through the first sampling pipe, thereby realizing the sampling and injection of solid and liquid samples by the device; that is, the multifunctional sampling and injection device in the present invention can sample and inject gas, liquid and solid at the same time, and the detection equipment in the present invention includes the multifunctional sampling and injection device and the detection unit. When the detection equipment with the multifunctional sampling and injection device detects the sample to be tested, its on-site applicability is greatly improved.

[0085] The multifunctional sampling and injection device of the present invention is also provided with a quantitative sampling gas circuit and a second sampling gas circuit. The quantitative sampling gas circuit includes a quantitative ring and a sampling pump. The sample to be tested entering the permeation cavity is quantitatively collected into the quantitative ring through the sampling pump; the second sampling gas circuit includes a second carrier gas circuit and a second sampling pipeline. The carrier gas enters the quantitative ring through the second carrier gas circuit and mixes with the sample to be tested in the quantitative ring to form a quantitative mixed gas, and then the quantitative mixed gas is injected through the second sampling gas circuit, thereby realizing quantitative sampling and injection of the sample to be tested. That is, the multifunctional sampling and injection device of the present invention can quantitatively sample and inject the target sample, and the detection equipment with the multifunctional sampling and injection device can realize the controllable sampling and injection amount of the target sample, thereby meeting the precise quantitative analysis of the sample to be tested, such as rapid screening of the target sample and concentration analysis of the target substance, which greatly improves the application range of the detection equipment.

[0086] Example 1

[0087] See also Figure 1 to Figure 6 This embodiment provides a multifunctional sampling and injection device, which includes: a guiding structure 201-A-1 or 201-B-1, a parsing unit and a gas path system.

[0088] The guiding structure 201-A-1 or 201-B-1 is used to introduce the gaseous sample to be tested;

[0089] The analysis unit includes an analysis port 101-11, an analysis chamber 101-21, a permeation chamber 101-31 and a storage chamber; wherein the input end of the analysis port 101-11 is sealed and connected to the guide structure 201-A-1 or 201-B-1, and the sample to be tested introduced from the guide structure 201-A-1 or 201-B-1 enters the analysis port 101-11; one end of the analysis chamber 101-21 is open and connected to the output end of the analysis port 101-11, and the other end of the analysis chamber 101-21 is connected to the input end of the air suction port 101-22, and the output end of the air suction port 101-22 is connected to an air suction pump. Under the negative pressure of the air suction pump, the sample to be tested enters the analysis chamber 101-31 from the guide structure 201-A-1 or 201-B-1 through the analysis port 101-11. 1-21; preferably, a first filter is provided between the air extraction port 101-22 and the air pump, and the first filter is used to filter or purify the gas discharged by the air pump; the permeation chamber 101-31 is separated from the analysis chamber 101-21 by a semipermeable membrane 101-32, and part of the sample to be tested in the analysis chamber 101-21 permeates into the permeation chamber 101-31 through the semipermeable membrane 101-32, and the two ends of the permeation chamber 101-31 are respectively connected with an air inlet 101-34 and an air outlet 101-35 through a pipeline; the storage chamber is located below the permeation chamber 101-31, and is connected with the permeation chamber 101-31 through a volatilization pipeline, and the storage chamber is used to collect and place solid or liquid samples, and the volatilized sample to be tested enters the permeation chamber 101-31 through the volatilization pipeline;

[0090] The gas circuit system includes a first sampling gas circuit, which includes a first carrier gas circuit and a first sampling pipeline, and the first carrier gas circuit includes a carrier gas interface 301-4 and a first carrier gas pipeline 301-5. One end of the first carrier gas pipeline 301-5 is connected to the carrier gas interface 301-4, and the other end is connected to the gas inlet 101-34; the first sampling pipeline is connected to the permeation chamber 101-31 through the gas outlet 101-35, and the carrier gas enters the permeation chamber 101-31 through the gas inlet 101-34 and mixes with the sample to be tested into a mixed gas. The mixed gas is sampled through the gas outlet 101-35 and the first sampling pipeline in turn.

[0091] Specifically, the setting of the guide structure 201-A-1 or 201-B-1 is mainly used to sample the sample in the gas state. Under the negative pressure of the suction pump, the sample to be tested enters the analysis chamber 101-21 from the guide structure 201-A-1 or 201-B-1 through the analysis port 101-11. Since the permeation chamber 101-31 is separated from the analysis chamber 101-21 only by the semipermeable membrane 101-32, a part of the sample to be tested passing above the semipermeable membrane 101-32 passes through the semipermeable membrane 101-32 due to the difference in gas concentration. 32 upper surface permeates into the permeation chamber 101-31, and another part of the sample to be tested is discharged by the suction pump through the air suction port 101-22, thereby realizing the collection of gaseous samples; in this embodiment, the permeation chamber 101-31 is located below the analysis chamber 101-21. In other embodiments, the permeation chamber 101-31 and the analysis chamber 101-21 may also have other positional relationships, and what needs to be satisfied is that the opening end of the permeation chamber 101-31 and the analysis chamber 101-21 are separated by a semipermeable membrane 101-32. In other embodiments, a circulation pipeline can also be set between the suction pump and the guide structure 201-A-1 or 201-B-1, and the excess gas discharged from the suction pump passes through the circulation pipeline and again passes through the guide structure 201-A-1 or 201-B-1 into the analysis chamber 101-21.

[0092] Furthermore, the storage chamber is used to collect and place solid or liquid samples. The samples in the storage chamber are volatilized by heat, and the volatilized samples to be tested enter the permeation chamber 101-31, thereby realizing the collection of solid or liquid samples.

[0093] Further, the first sampling gas circuit includes a first carrier gas circuit and a first sampling pipeline, the first carrier gas circuit includes a carrier gas interface 301-4 and a first carrier gas pipeline 301-5, the carrier gas entering from the carrier gas interface 301-4 sequentially passes through the first carrier gas pipeline 301-5 and the gas inlet 101-34 into the permeation chamber 101-31, the carrier gas is mixed with the sample to be tested in the permeation chamber 101-31 to form a mixed gas, and then the mixed gas is sequentially injected through the gas outlet 101-35 and the first sampling pipeline. Among them, the carrier gas is used to bring the sample to be tested into the detection unit for detection.

[0094] Preferably, a first two-position three-way valve 301-11 may be provided on the first carrier gas pipeline 301-5 to control the on-off of the first carrier gas path. Of course, no excessive restrictions are made here, as long as the on-off of the first carrier gas path can be achieved.

[0095] As an example, a positioning bead 101-12 is provided on the analysis port 101-11, and a guide structure is provided at the rear end of the guide structure 201-A-1 or 201-B-1. A positioning groove 201-2 is provided on the guide structure, and the positioning groove 201-2 is cooperatively connected with the positioning bead 101-12.

[0096] For details, see Figure 1 to Figure 3 The guide structure 201-A-1 or 201-B-1 has an introduction port, and the output end of the introduction port is inserted into the analysis port 101-11. In order to facilitate the connection and installation of the guide structure 201-A-1 or 201-B-1 and the analysis port 101-11, a guide structure is set at the rear end of the guide structure 201-A-1 or 201-B-1, and a positioning groove 201-2 that can cooperate with the positioning top bead 101-12 set on the analysis port 101-11 is set on the guide structure. During installation, the guide structure 201-A-1 or 201-B-1 is inserted into the analysis port 101-11 with force, and the positioning top bead 101-12 on the analysis port 101-11 is connected with the positioning groove 201-2 on the guide structure. When the guide structure 201-A-1 or 201-B-1 needs to be removed from the analysis port 101-11, it only needs to be pulled out with force. In the present invention, the specific shape and size of the guide structure and the analysis port 101-11 can be set as needed, and no excessive restrictions are made here. In addition, the specific shape and size of the positioning top bead 101-12 and the positioning groove 201-2 are also not excessively restricted, and they can meet the needs of practical applications.

[0097] As an example, a sealing ring 201-1 is provided at the front end of the guide structure, and the sealing ring 201-1 is used to seal between the guide structure 201-A-1 or 201-B-1 and the analysis port 101-11. Preferably, the sealing ring 201-1 is an O-ring. As an example, the guide structure 201-A-1 or 201-B-1 is made of PTFE or PEEK material.

[0098] Specifically, PTFE (polytetrafluoroethylene) and PEEK (polyetheretherketone) materials are resistant to high temperatures and have good thermal insulation properties. During the heating process, the guide structure 201-A-1 or 201-B-1 will release trace gases when heated. In this embodiment, the guide structure 201-A-1 or 201-B-1 is made of materials that are resistant to high temperatures and have good thermal insulation properties. On the one hand, it can reduce the release of trace gases caused by heating, thereby reducing the impact of trace gases on the sample to be tested. On the other hand, it can prevent the operator from coming into contact with the guide structure 201-A-1 or 201-B-1 and being burned when introducing the sample to be tested. As an example, the front end of the guide structure 201-A-1 or 201-B-1 is detachably connected to a sampling head 201-3 to improve the gas sampling effect.

[0099] For details, see Figure 2 The sampling head 201-3 is a hollow tubular structure; when using wiping sampling, test paper spotting, thermal desorption sampling, Figure 1 The guiding structure 201-A-1 in the embodiment can be used when the suction sampling method is adopted. Figure 2 The guide structure 201-B-1 is connected to the sampling head 201-3 with a hollow tubular structure. In this embodiment, the sampling head 201-3 is a hollow tubular structure, which can be but is not limited to a stainless steel tube with a certain strength.

[0100] Preferably, see Figure 2 The sampling head 201-3 in this embodiment is a hollow tubular structure, and the inner diameter of the hollow tube of the sampling head 201-3 is 2 to 4 mm. The sampling head 201-3 is set to a hollow tubular structure in order to facilitate gas sampling and improve the effect of gas sampling, but the sampling head 201-3 can also be set to other structures. There is no excessive restriction on other structural forms and sizes of the sampling head 201-3.

[0101] As an example, both the analysis port 101 - 11 and the analysis chamber 101 - 21 are provided with heating devices, and a heat preservation sleeve 101 - 23 is provided on the periphery thereof to increase the heating rate of the entire analysis unit.

[0102] As an example, the analysis port 101 - 11 and the analysis cavity 101 - 21 are both made of metal with good thermal conductivity to achieve rapid temperature rise of the analysis port 101 - 11 and the analysis cavity 101 - 21.

[0103] Specifically, in this embodiment, the analytical port 101-11 and the analytical cavity 101-21 are both made of copper; in addition, in order to ensure the analytical effect of the sample to be tested, the width of the analytical port 101-11 is usually 5 mm or less than the width of the wiping sampling paper / sheet, and the height of the analytical port 101-11 is 2 to 3 times the thickness of the wiping paper / sheet. However, the size of the analytical port 101-11 in the present invention can be set according to actual needs, and no excessive restrictions are made here.

[0104] For example, see Figure 3 , Figure 5An air guide platform 101-36 is provided in the permeation chamber 101-31. The air guide platform 101-36 is located below the semipermeable membrane 101-32 and forms a vortex flow channel between the air guide platform 101-36 and the semipermeable membrane 101-32. The air inlet 101-34 is connected to one end of the vortex flow channel, and the air outlet 101-35 is connected to the other end of the vortex flow channel. The vapor of the sample to be tested entering the permeation chamber 101-31 passes through the vortex flow channel (in the direction of the arrow) under the action of the carrier gas, and then flows out through the air outlet 101-35 of the permeation chamber 101-31, thereby ensuring the transmission effect of the sample to be tested in the permeation chamber 101-31.

[0105] Preferably, in order to ensure the installation strength of the semipermeable membrane 101-32 and the penetration effect of the sample to be tested, a mesh fixing sheet 101-33 is further provided on the upper surface of the semipermeable membrane 101-32, and the semipermeable membrane 101-32 is fixed by the mesh fixing sheet 101-33.

[0106] As an example, a sample box 101-41 is placed in the storage cavity, and a volatilization hole 101-42 is opened on the sample box 101-41. The volatilization hole 101-42 is connected to the permeation cavity 101-31 through a volatilization pipe. Solid or liquid samples are collected and placed in the sample box 101-41, and a heating device is arranged around the sample box 101-41. The sample to be tested in the sample box 101-41 is volatilized by heat, and the volatilized sample to be tested enters the permeation cavity 101-31 through the volatilization hole 101-42.

[0107] Preferably, in order to prevent the sample box 101-41 and the entire analysis unit from being contaminated due to excessive concentration of sample volatilization, a semipermeable membrane 101-43 is attached to the top of the sample box 101-41. The sample to be tested volatilized in the sample box 101-41 passes through the semipermeable membrane 101-43 and the volatilization hole 101-42 on the top of the sample box 101-41, and enters the permeation cavity 101-31 through the volatilization pipe.

[0108] Specifically, the sample box 101-41 can be completely wrapped by the semipermeable membrane 101-43, or a semipermeable membrane 101-43 can be attached to the top of the sample box 101-41. Specifically, the semipermeable membrane 101-43 can be provided with one layer, two layers or multiple layers. There is no excessive limitation on the number of layers of the semipermeable membrane 101-43.

[0109] As an example, a heating lifting platform 101 - 51 is provided at the bottom of the sample box 101 - 41, and the heating lifting platform 101 - 51 is used to position and lift the sample box 101 - 41.

[0110] Specifically, a heating lifting platform 101-51 is provided at the bottom of the sample box 101-41. On the one hand, the lifting and lowering of the heating lifting platform 101-51 facilitates loading and unloading of samples in the sample box 101-41. Meanwhile, the heating function of the heating lifting platform 101-51 can also realize heating of the sample box 101-41.

[0111] Preferably, as an example, the sample box 101-41 is made of magnetic metal material, and the heating lifting platform 101-51 is also magnetic. Such a configuration facilitates the positioning and lifting operations of the sample box 101-41.

[0112] As an example, a high temperature resistant sealing ring 101-52 is provided on the upper surface of the heating lifting platform 101-51, which is used to seal the analysis channel during sample analysis and to seal the sampling and injection channels during sampling and injection to prevent the external gas environment from interfering with the detection of the sample to be tested. Preferably, the sealing ring 101-52 is an O-ring.

[0113] In order to better understand the multifunctional sampling and injection device in the present invention, the specific embodiment of the present invention also provides a detection device, see Figure 6 to Figure 9 The detection device includes: a multifunctional sampling and injection device as described above in any of the embodiments, and a detection unit.

[0114] Among them, the detection unit includes a gas chromatography system, an ion mobility spectrometry system, a mass spectrometry system and their combined devices, and the injection output end of the multifunctional sampling and injection device is respectively connected to the injection input end of the gas chromatography system, the ion mobility spectrometry system, the mass spectrometry system and their combined devices.

[0115] Specifically, the gas chromatography system includes a chromatography column system and a chromatography detector, and the sampling gas enters the chromatography column system through the first injection pipe; the ion mobility spectrometer system includes an ionization chamber, a migration zone and a Faraday cup, and the sampling gas enters the ionization chamber through the first injection pipe; the mass spectrometer system includes an ionization chamber, a mass analyzer, a mass spectrometer detector and a vacuum system, and the sampling gas enters the ionization chamber through the first injection pipe; the coupling device is a combination of any two or three of the gas chromatography system, the ion mobility spectrometer system and the mass spectrometer system. Among them, the mixed gas enters the gas chromatography system, the ion mobility spectrometer system, the mass spectrometer system and the coupling device through the injection input end to realize detection, and the specific structures of the gas chromatography system, the ion mobility spectrometer system, the mass spectrometer system and the coupling device are not introduced in detail here.

[0116] The embodiment of the present invention further provides a detection method, which uses the above detection device to detect a sample to be detected.

[0117] Specifically, the multifunctional sampling and injection device samples the sample to be tested in the gas, liquid or solid state, and mixes it with the carrier gas to form a mixed gas. The mixed gas is injected into each detection unit through the first injection gas path to achieve qualitative detection of the sample to be tested. The multifunctional sampling and injection device can sample and inject gas, liquid and solid at the same time. The on-site applicability of the detection equipment with the multifunctional sampling and injection device is greatly improved.

[0118] Example 2

[0119] See also Figures 1 to 9 This embodiment provides a multifunctional sampling and injection device. The difference between this embodiment and embodiment 1 mainly lies in that the gas path system in this embodiment also includes a quantitative sampling gas path and a second injection gas path.

[0120] Among them, the quantitative sampling gas circuit includes a quantitative ring 301-6 and a sampling pump, wherein the two ends of the quantitative ring 301-6 are respectively connected to the gas outlet 101-35 and the sampling pump through control valves, and the sampling pump collects the sample to be tested in the permeation cavity 101-31 into the quantitative ring 301-6; preferably, a second filter is provided at the front end of the sampling pump, and the second filter is used to filter or purify the gas discharged by the sampling pump.

[0121] The second sampling gas circuit includes a second carrier gas circuit and a second sampling pipeline, the second carrier gas circuit includes a carrier gas interface 301-4 and a second carrier gas pipeline 301-7, one end of the second carrier gas pipeline 301-7 is connected to the carrier gas interface 301-4, and the other end is connected to the quantitative ring 301-6 through a control valve, and the carrier gas enters the quantitative ring 301-6 and mixes with the sample to be tested to form a quantitative mixed gas; the second sampling pipeline is connected to the quantitative ring 301-6 through a control valve, and a quantitative mixed gas is sampled through the second sampling pipeline.

[0122] Specifically, the quantitative ring 301-6 is connected to the gas outlet 101-35 of the permeation chamber 101-31 by switching the interface of the control valve, and the sample to be tested in the permeation chamber 101-31 is quantitatively collected into the quantitative ring 301-6 by the sampling pump, thereby realizing quantitative sampling of the sample to be tested; at the same time, the carrier gas interface 301-4 is connected to the quantitative ring 301-6 by switching the interface of the control valve, and the carrier gas enters the quantitative ring 301-6 and mixes with the sample to be tested collected in the quantitative ring 301-6 to form a quantitative mixed gas, and the mixed gas is sampled through the second sampling pipeline; the multifunctional sampling and injection device in this embodiment can realize quantitative sampling and injection of samples in solid, liquid or gaseous states, thereby meeting the precise quantitative analysis of the samples to be tested, such as rapid screening of target samples and concentration analysis of target substances.

[0123] As an example, the control valve is a six-way valve 301 - 3 .

[0124] For details, see Figure 6 As shown, the six-way valve 301-3 has 6 interfaces, the interface from the upper left corner is interface 1, and in clockwise direction, they are interfaces 2, 3, 4, 5, and 6. However, there is no excessive restriction on the number of interfaces of the control valve, and it can be 8, 10 or other interfaces.

[0125] For example, see Figure 6 The input end of the quantitative ring 301-6 is connected to the No. 6 interface of the six-way valve 301-3, and the output end is connected to the No. 3 interface of the six-way valve 301-3; the output end of the gas outlet 101-35 is connected to the No. 5 interface of the six-way valve 301-3; the sampling pump is connected to the No. 4 interface of the six-way valve 301-3 through a pipeline; the input end of the second carrier gas pipeline 301-7 is connected to the carrier gas interface 301-4, and the output end is connected to the No. 1 interface of the six-way valve 301-3; the input end of the second sample injection pipeline is connected to the No. 2 interface of the six-way valve 301-3. However, the connection method of the interface of the six-way valve 301-3 is not limited to this.

[0126] For example, see Figure 6 , a first two-position three-way valve 301 - 11 is provided on the first carrier gas pipeline 301 - 5;

[0127] A second two-position three-way valve 301-12 is provided between the second carrier gas pipeline 301-7 and the carrier gas interface 301-4, one contact of the second two-position three-way valve 301-12 is connected to the carrier gas interface 301-4, and the other two contacts are connected to the first carrier gas pipeline 301-5 and the second carrier gas pipeline 301-7 respectively;

[0128] A third two-position three-way valve 301-13 is provided on the pipeline between the sampling pump and the interface No. 301-34 of the six-way valve, and two contacts of the third two-position three-way valve 301-13 are respectively connected to the interface No. 301-34 of the six-way valve and the sampling pump through pipelines;

[0129] In addition, since the output end of the gas outlet 101-35 is connected to the No. 5 interface of the six-way valve 301-3, and the output end of the gas outlet 101-35 is also connected to the first sample injection pipeline, wherein the first sample injection pipeline can be a separate pipeline connected to the detection unit, and can also be connected to the second sample injection pipeline through the No. 5 interface of the six-way valve 301-3, and then through the No. 4 interface of the six-way valve 301-3 through the third two-position three-way valve 301-13; at this time, a three-way valve 301-2 can be set on the second sample injection pipeline, and the two ends of the three-way valve 301-2 are connected to the second sample injection pipeline, and the other end is connected to the third two-position three-way valve 301-13. In other specific embodiments, the number and location of the first two-position three-way valve 301-11, the second two-position three-way valve 301-12, the third two-position three-way valve 301-13, and the three-way valve 301-2 are not limited to this, and no excessive restrictions are made here.

[0130] In order to better understand the multifunctional sampling and injection device in the present invention, the specific embodiment of the present invention also provides a detection device, see Figure 6 to Figure 9 , the detection device comprises: the multifunctional sampling and injection device as described above in any one of the embodiments, and a detection unit;

[0131] Among them, the detection unit includes a gas chromatography system, an ion mobility spectrometry system, a mass spectrometry system and their combined devices, and the injection output end of the multifunctional sampling and injection device is respectively connected to the injection input end of the gas chromatography system, the ion mobility spectrometry system, the mass spectrometry system and their combined devices.

[0132] Specifically, the mixed gas enters the gas chromatography system, ion mobility spectrometry system, mass spectrometry system and their combined devices through the sample inlet port for detection, and the specific structures of the gas chromatography system, ion mobility spectrometry system, mass spectrometry system and their combined devices are not described in detail here. A specific embodiment of the present invention also provides a detection method, using the above detection equipment to detect the sample to be detected.

[0133] Specifically, the detection equipment can realize the controllable sampling and injection volume of the target sample, thereby meeting the precise quantitative analysis of the sample to be tested, such as the rapid screening of the target sample and the concentration analysis of the target substance, which greatly improves the application scope of the detection equipment.

[0134] As an embodiment, when it is necessary to perform quantitative detection on a gas sample, the detection method in this embodiment is specifically as follows:

[0135] Quantitative sampling: see Figure 7In the gas path connection state, the guide structure 201-B-1 is sealed and connected with the analysis port 101-11, the suction pump and the sampling pump are started, and the front end of the guide structure 201-B-1 is aimed at the detection target. The sample to be tested enters the analysis port 101-11 and then enters the analysis chamber 101-21 under the negative pressure of the suction pump. A part of the sample to be tested passes over the semipermeable membrane 101-32 and is discharged by the suction pump through the air outlet 101-22; due to the difference in gas concentration, the sample to be tested passing over the semipermeable membrane 101-32 A portion of the sample to be tested permeates into the osmotic chamber 101-31 through the upper surface of the semipermeable membrane 101-32; the sample to be tested flows through the swirling flow channel formed by the gas guide platform 101-36 and the semipermeable membrane 101-32, through the gas outlet 101-35 of the osmotic chamber 101-31, and then flows into the quantitative ring 301-6 through the No. 5 and No. 6 interfaces of the six-way valve 301-3, and the excess gas flows out through the No. 3 and No. 4 interfaces of the six-way valve 301-3, and the target sample to be tested with a determined volume is stored in the quantitative ring 301-6, completing quantitative sampling;

[0136] Quantitative injection, see Figure 8 In the gas path connection state, the carrier gas enters the quantitative ring 301-6 through the carrier gas interface 301-4, the second carrier gas pipeline 301-7, and the No. 1 and No. 6 interfaces of the six-way valve 301-3, and is mixed with the sample to be tested temporarily stored in the quantitative ring 301-6 to form a mixed gas. The mixed gas is injected into the detection unit through the No. 3 interface of the six-way valve 301-3 and the No. 2 interface through the second injection pipeline for quantitative detection.

[0137] As another embodiment, when it is necessary to perform qualitative detection on the gas sample, the detection method in this embodiment is specifically as follows:

[0138] See also Fig. 9 In the state, the front end of the guide structure 201-B-1 is aligned with the detection target object, and the gas to be detected enters the analysis port 101-11 under the negative pressure of the suction pump, and then enters the analysis cavity 101-21. A part of the sample to be detected passes through the top of the semipermeable membrane 101-32 and is discharged by the suction pump through the air suction port 101-22; due to the difference in gas concentration, a part of the sample to be detected passing through the top of the semipermeable membrane 101-32 penetrates into the permeation cavity 101-31 through the upper surface of the semipermeable membrane 101-32. ; The carrier gas passes through the carrier gas interface 301-4 through the first carrier gas pipeline 301-5 and the gas inlet 101-34 into the vortex flow channel of the permeation chamber 101-31, and is mixed with the sample to be tested to form a mixed gas; the mixed gas passes through the gas outlet 101-35 of the permeation chamber 101-31, and then through the first sampling pipeline (then through the No. 5 and No. 4 interfaces of the six-way valve 301-3 and through the third two-position three-way valve 301-13 and the 1 interface connected to the three-way) to the detection unit for qualitative detection of the gas sample.

[0139] In summary, the multifunctional sampling and injection device of the present invention comprises a guiding structure, an analysis port, an analysis chamber, an osmotic chamber, a first carrier gas path and a first injection gas path, wherein the guiding structure is connected to the input end of the analysis port and is used to introduce a gaseous sample to be tested. Since the osmotic chamber and the analysis chamber are separated only by a semipermeable membrane, a part of the sample to be tested that enters the analysis chamber passes through the semipermeable membrane into the osmotic chamber to complete the sampling. At the same time, the carrier gas enters the osmotic chamber and mixes with the sample to be tested to form a mixed gas. The mixed gas is injected through the first injection pipe, thereby realizing the sampling and injection of the gaseous sample by the device. The device of the present invention is also provided with a storage The multifunctional sampling and injection device of the present invention can simultaneously perform sampling and injection on gas, liquid and solid, and the detection device of the present invention comprises the multifunctional sampling and injection device and the detection unit. When the detection device with the multifunctional sampling and injection device detects the sample to be detected, its on-site applicability is greatly improved.

[0140] The multifunctional sampling and injection device of the present invention is also provided with a quantitative sampling gas path and a second injection gas path, the quantitative sampling gas path includes a quantitative ring and a sampling pump, and the sample to be tested entering the permeation cavity is quantitatively collected into the quantitative ring by the sampling pump; the second injection gas path includes a second carrier gas path and a second injection pipeline, and the carrier gas enters the quantitative ring through the second carrier gas path and mixes with the sample to be tested in the quantitative ring into a quantitative mixed gas, and then the quantitative mixed gas is injected through the second injection gas path, thereby realizing quantitative sampling and injection of the sample to be tested, that is, the multifunctional sampling and injection device of the present invention can quantitatively sample and inject the target sample, and the detection equipment with the multifunctional sampling and injection device can realize the controllable sampling and injection amount of the target sample, thereby meeting the accurate quantitative analysis of the sample to be tested, such as the rapid screening of the target sample and the concentration analysis of the target substance, and greatly improving the application range of the detection equipment. Therefore, the present invention effectively overcomes various shortcomings in the prior art and has a high industrial utilization value.

[0141] The above embodiments are merely illustrative of the principles and effects of the present invention, and are not intended to limit the present invention. Anyone familiar with the art may modify or alter the above embodiments without departing from the spirit and scope of the present invention. Therefore, all equivalent modifications or alterations made by a person of ordinary skill in the art without departing from the spirit and technical concept disclosed by the present invention shall still be covered by the claims of the present invention.

Claims

1. A multifunctional sampling and injection device, characterized in that: The multifunctional sampling and injection device comprises: A guide structure, wherein the guide structure is used to introduce a sample to be tested; A parsing unit, the parsing unit comprising a parsing port, a parsing cavity, a permeation cavity and a storage cavity; Wherein, the input end of the analysis port is sealed and connected to the guide structure; One end of the analysis chamber is connected to the output end of the analysis port, and the other end is connected to the input end of the air suction port. The output end of the air suction port is connected to an air suction pump. The sample to be tested enters the analysis port and the analysis chamber in sequence from the guide structure under the negative pressure of the air suction pump. The osmotic chamber is separated from the analytical chamber by a semipermeable membrane, and part of the sample to be tested in the analytical chamber permeates into the osmotic chamber through the semipermeable membrane, and both ends of the osmotic chamber are respectively connected with an air inlet and an air outlet through a pipeline; the storage chamber is located below the osmotic chamber and is connected to the osmotic chamber through a volatilization pipeline, and the storage chamber is used to collect and place samples, and the volatilized sample to be tested enters the osmotic chamber through the volatilization pipeline; A gas circuit system, wherein the gas circuit system comprises a first sample inlet gas circuit, the first sample inlet gas circuit comprises a first carrier gas circuit and a first sample inlet pipeline, the first carrier gas circuit comprises a carrier gas interface and a first carrier gas pipeline, one end of the first carrier gas pipeline is connected to the carrier gas interface, and the other end is connected to the gas inlet; the first sample inlet pipeline is connected to the permeation cavity through the gas outlet, the carrier gas enters the permeation cavity through the gas inlet and mixes with the sample to be tested to form a mixed gas, and the mixed gas is sampled through the gas outlet and the first sample inlet pipeline in sequence; The gas circuit system also includes a quantitative sampling gas circuit and a second sampling gas circuit; The quantitative sampling gas circuit includes a quantitative ring and a sampling pump, wherein the two ends of the quantitative ring are connected to the gas outlet and the sampling pump respectively through a control valve, and the sampling pump collects the sample to be tested in the permeation cavity into the quantitative ring; The second sampling gas circuit includes a second carrier gas circuit and a second sampling pipeline, the second carrier gas circuit includes a carrier gas interface and a second carrier gas pipeline, one end of the second carrier gas pipeline is connected to the carrier gas interface, and the other end is connected to the quantitative loop through a control valve, the carrier gas enters the quantitative loop and mixes with the sample to be tested to form a quantitative mixed gas; the second sampling pipeline is connected to the quantitative loop through a control valve, and the quantitative mixed gas is sampled through the second sampling pipeline.

2. The multifunctional sampling and injection device according to claim 1, characterized in that: The control valve is a six-way valve.

3. The multifunctional sampling and injection device according to claim 1, characterized in that: The analysis port is provided with a positioning top bead, the rear end of the guide structure is provided with a guide structure, the guide structure is provided with a positioning groove, and the positioning groove is matched and connected with the positioning top bead; A sealing ring is provided at the front end of the guide structure, and the sealing ring is used for sealing between the guide structure and the analysis port; The guide structure is made of PTFE or PEEK material.

4. The multifunctional sampling and injection device according to claim 3, characterized in that: The front end of the guide structure is detachably connected with a sampling head.

5. The multifunctional sampling and injection device according to claim 1, characterized in that: The analysis port and the analysis cavity are both provided with a heating device, and the periphery thereof is provided with a heat preservation sleeve; The analysis port and the analysis cavity are both made of red copper with good thermal conductivity.

6. The multifunctional sampling and injection device according to claim 1, characterized in that: An air guide platform is provided in the osmotic cavity, the air guide platform is located below the semipermeable membrane, and a vortex flow channel is formed between the air guide platform and the semipermeable membrane; A mesh fixing sheet is also provided on the upper surface of the semipermeable membrane, and the mesh fixing sheet is used to fix the semipermeable membrane.

7. The multifunctional sampling and injection device according to claim 1, characterized in that: A sample box is placed in the storage cavity, and a volatilization hole is opened on the sample box. The volatilization hole is connected with the permeation cavity through a volatilization pipeline, and the volatilized sample to be tested enters the permeation cavity through the volatilization hole; A semipermeable membrane is attached to the top of the sample box; A heating lifting platform is provided at the bottom of the sample box, and the heating lifting platform is used to position and lift the sample box; A sealing ring is arranged on the upper surface of the heating lifting platform.

8. A detection device, characterized in that: The detection equipment comprises: The multifunctional sampling and injection device according to any one of claims 1 to 7; and The detection unit includes a gas chromatography system, an ion mobility spectrometry system, a mass spectrometry system and a combination thereof, and the injection output end of the multifunctional sampling and injection device is respectively connected to the injection input end of the gas chromatography system, the ion mobility spectrometry system, the mass spectrometry system and a combination thereof.

9. A detection method, characterized in that: The sample to be tested is tested using the testing device described in claim 8.

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