refrigerator

Abstract

The present invention relates to a refrigerator, which includes a microfluidic detection system for qualitatively or quantitatively detecting preset detection parameters of a sample liquid, wherein the microfluidic detection system includes: a microfluidic biochip, having an injection port, a connecting port, and a detection pool formed therein, wherein the injection port, the detection pool, and the connecting port are sequentially connected through a microfluidic channel; a chip mounting mechanism, which is used to mount the microfluidic biochip; a sample liquid driving device, which is sealedly connected to the connecting port to cause the sample liquid in contact with the injection port to flow into the microfluidic channel and flow to the detection pool through the microfluidic channel; and a detection mechanism, which is used to detect the detection pool to obtain the preset detection parameters of the sample liquid. Thus, not only can the injection and detection operations be smoothly performed, but also the accuracy of the detection results can be ensured through the precise control of the injection. At the same time, the structure of the microfluidic detection system is simplified to avoid it occupying too much space on the refrigerator.

Description

Technical Field

[0001] The invention relates to refrigeration and freezing technology, in particular to a refrigerator. Background Art

[0002] As people's living standards improve, they usually need to test some edible food materials for pesticide residues, viruses, nutrients or other aspects in daily life to obtain the condition of the food materials qualitatively or quantitatively. For example, due to the problem of pesticide abuse, the fruits, vegetables and agricultural and sideline products we buy daily may have excessive pesticide residues. If the excessive pesticide residues in these foods are not discovered in time, they will cause great harm to the human body after ingestion. For another example, breastfeeding, which is currently advocated, is the best feeding for infants only when breast milk has normal nutritional value. However, if the mother is sick, takes medicine, undergoes surgery or other situations, the nutrient content in the milk she secretes may decrease or even produce viruses, thereby affecting the growth, development and health of the baby.

[0003] However, the existing detection systems are generally independent, occupying space and inconvenient to store. After the detection device is stored, people may forget to use it, or they may find it troublesome to take it out and use it. For this reason, there is a solution in the prior art to integrate the detection system for pesticide residue detection into the refrigerator. The existing pesticide residue detection system integrated in the refrigerator detects the gas volatilized by the food or the condensed water flowing from the food. Not only does it require the arrangement of gas collection or liquid collection devices, resulting in a very complex structure and occupying a large space, affecting the user's normal storage space, but the detection accuracy is very low, which greatly affects the user experience. Summary of the invention

[0004] An object of the present invention is to overcome at least one defect of the prior art and to provide a refrigerator integrated with a microfluidic detection system of a simple structure.

[0005] A further object of the present invention is to improve the operational convenience for users to replace microfluidic biochips.

[0006] Another further object of the present invention is to reduce the vibration of the microfluidic detection system, reduce its operating noise, and improve its heat dissipation efficiency.

[0007] In order to achieve the above object, the present invention provides a refrigerator, comprising a microfluidic detection system for performing qualitative or quantitative detection of preset detection parameters of a sample liquid, the microfluidic detection system comprising:

[0008] A microfluidic biochip, comprising an injection port, a communication port, and a detection pool formed inside the chip, wherein the injection port, the detection pool, and the communication port are sequentially connected through a microchannel;

[0009] A chip mounting mechanism, used for mounting the microfluidic biochip;

[0010] a sample liquid driving device, which is sealedly connected to the communication port to cause the sample liquid in contact with the injection port to flow into the microfluidic channel and then flow to the detection cell through the microfluidic channel; and

[0011] The detection mechanism is used to detect the detection pool to obtain preset detection parameters of the sample liquid.

[0012] Optionally, the sample liquid driving device forms a fluid-tight connection with the communication port through a sealing docking mechanism; and

[0013] A plug-in needle protruding outward is fixedly provided at the connecting port of the microfluidic biochip, the internal flow channel of the plug-in needle is sealedly connected with the connecting port, and the plug-in needle is inserted into the interior of the sealing docking mechanism and forms a fluid-tight connection with the sealing docking mechanism, and the sealing docking mechanism is fluid-tightly connected with the sample liquid driving device, so that the sample liquid driving device is sealedly connected with the connecting port.

[0014] Optionally, the end surface of the extended end of the plug pin is a continuous and smooth hemispherical surface, and the pinhole of the plug pin for fluid communication with the sealing docking mechanism is formed on the circumferential side surface of the section of the plug pin located inside the sealing docking mechanism.

[0015] Optionally, the microfluidic detection system further comprises:

[0016] The chip ejection mechanism is used to operably release the support effect of the chip mounting mechanism on the microfluidic biochip to release the microfluidic biochip.

[0017] Optionally, the chip mounting mechanism comprises two elastic clamps arranged opposite to each other to apply opposite forces to the microfluidic biochip between the two elastic clamps, so that the microfluidic biochip is clamped between the two elastic clamps; and

[0018] The chip ejection mechanism is configured to operably apply forces in opposite directions to the two elastic clamps to cause the two elastic clamps to elastically deform in directions away from each other, thereby releasing the clamping effect of the two elastic clamps on the microfluidic biochip.

[0019] Optionally, the microfluidic detection system further comprises:

[0020] A sample table, used to place a sample cup, wherein the sample cup is used to hold a sample liquid; and

[0021] The sample stage is configured to move in a controlled or operable manner so as to transport the sample cup placed thereon to a position allowing the sample liquid in the sample cup to contact the sample inlet of the microfluidic biochip.

[0022] Optionally, the microfluidic biochip is arranged above the sample stage, and the sample inlet is located at the bottom of the microfluidic biochip; and

[0023] The microfluidic detection system also includes a lifting mechanism for driving the sample stage to move up and down, so that the sample stage switches between a detection position that allows a sample liquid in a sample cup placed on the sample stage to contact the injection port and an initial position that is a preset distance below the detection position.

[0024] Optionally, the microfluidic detection system further comprises:

[0025] a buffer bottle for containing a buffer; and

[0026] The buffer driving device is connected to the buffer bottle to controllably drive the buffer in the buffer bottle into the sample cup placed on the sample stage, so that the buffer is mixed with the sample in the sample cup to generate a sample liquid.

[0027] Optionally, the sample liquid driving device is disposed adjacent to the side of the microfluidic biochip in the lateral direction, and includes a driving motor that is suspended.

[0028] Optionally, the microfluidic detection system further comprises:

[0029] The sample table is used to place a sample cup, and the sample cup is used to hold the sample liquid; wherein

[0030] The sample stage includes a support platform for supporting a sample cup and an oscillator arranged on the support platform. The oscillator is used to oscillate the sample cup after the sample cup is placed on the support platform, so that the buffer solution and the sample in the sample cup are fully mixed to produce the sample liquid.

[0031] Optionally, the microfluidic detection system further comprises:

[0032] A housing, wherein the chip mounting mechanism, the sample liquid driving device, the detection mechanism and at least a portion of the microfluidic biochip are all disposed in the housing; and

[0033] The shell is provided with structural connectors for connecting to the body or door of the refrigerator, and electrical connectors for forming an electrical connection between the microfluidic detection system and the electronic control device of the refrigerator, so as to allow the microfluidic detection system to be installed as a whole to the body or door of the refrigerator.

[0034] Optionally, the refrigerator further comprises:

[0035] a box body, defining a storage space for storing items therein; and

[0036] A door body is connected to the box body and is used to open and / or close the storage space; wherein

[0037] The microfluidic detection system is arranged on the door body.

[0038] The refrigerator of the present invention includes a microfluidic detection system, and the microfluidic detection system includes a microfluidic biochip for providing detection conditions and a detection environment, a chip mounting mechanism for mounting the microfluidic biochip, a sample liquid driving device for accurately controlling the flow of sample liquid into the microfluidic biochip, and a detection mechanism for performing a detection operation. The combination of the structure and function of these four modules can not only smoothly perform the sample injection and detection operations, but also ensure the accuracy of the detection results through the precise control of the sample injection. On this basis, the structure of each module is very simple, which simplifies the structure of the microfluidic detection system and avoids it from occupying too much space on the refrigerator.

[0039] Furthermore, the microfluidic detection system also includes a chip ejection mechanism, by which the user can release the support of the chip mounting mechanism and the microfluidic biochip, thereby releasing the microfluidic biochip. The user can then easily take out the microfluidic biochip or the microfluidic biochip can fall under its own gravity, thereby simplifying the user's operation process and improving the convenience of the user in replacing the microfluidic biochip.

[0040] Furthermore, the sample liquid driving device has a driving motor, which is suspended in the air and does not contact other structures, thereby preventing the vibration generated by the driving motor from being transmitted to the microfluidic biochip or other structures during operation, thereby reducing the vibration of the entire microfluidic detection system and reducing its operating noise. In addition, since the driving motor is used at a high frequency and generates a large amount of heat, the suspended setting of the driving motor also increases the size of the space around it, which is conducive to heat dissipation.

[0041] Based on the following detailed description of specific embodiments of the present invention in conjunction with the accompanying drawings, those skilled in the art will become more aware of the above and other objects, advantages and features of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0042] Hereinafter, some specific embodiments of the present invention will be described in detail in an exemplary and non-limiting manner with reference to the accompanying drawings. The same reference numerals in the accompanying drawings indicate the same or similar components or parts. It should be understood by those skilled in the art that these drawings are not necessarily drawn to scale. In the accompanying drawings:

[0043] Figure 1 is a schematic structural diagram of a refrigerator according to an embodiment of the present invention;

[0044] Figure 2 is a schematic structural diagram of a microfluidic detection system according to an embodiment of the present invention;

[0045] Figure 3 is a schematic structural exploded diagram of a microfluidic detection system according to an embodiment of the present invention;

[0046] Figure 4 is a schematic structural diagram of the internal structure of a microfluidic detection system according to an embodiment of the present invention;

[0047] Figure 5 is a schematic structural decomposition diagram of the internal structure of a microfluidic detection system according to an embodiment of the present invention;

[0048] Figure 6 is a schematic cross-sectional view of a microfluidic biochip according to an embodiment of the present invention;

[0049] Figure 7 is a schematic cross-sectional view of a sample liquid driving device and a microfluidic biochip and a structure connected therebetween according to an embodiment of the present invention;

[0050] Figure 8 is a schematic cross-sectional exploded view of a sealing docking mechanism and a microfluidic biochip according to another embodiment of the present invention;

[0051] Fig. 9 yes Figure 8 A schematic enlarged view of the middle portion A;

[0052] Fig.10 is a schematic structural diagram of a microfluidic biochip, a chip mounting mechanism and a chip ejection mechanism according to an embodiment of the present invention;

[0053] Fig.11 is a schematic structural diagram of a lifting mechanism and a sample stage in a disassembled state according to an embodiment of the present invention;

[0054] Fig.12 is a schematic structural exploded view of a door body according to an embodiment of the present invention. DETAILED DESCRIPTION

[0055] The invention provides a refrigerator. Figure 1 is a schematic structural diagram of a refrigerator according to an embodiment of the present invention. Figure 1The refrigerator 100 of the present invention comprises a box body 200 and a door body 300. The box body 200 defines a storage space for storing articles, and the door body 300 is connected to the box body 200 and is used to open and / or close its storage space.

[0056] In particular, the refrigerator 100 also includes a microfluidic detection system 1, which is used to perform qualitative or quantitative detection on preset detection parameters of the sample liquid. The preset detection parameters can be, for example, pesticide residue parameters used to indicate whether the pesticide residue exceeds the standard and / or the specific value of the pesticide residue, nutritional parameters used to indicate whether the nutritional elements meet the standards and / or the specific content of the nutritional elements, specific substance parameters used to indicate whether specific harmful substances (such as specific viruses) exceed the standard and / or the specific content, and so on.

[0057] Figure 2 is a schematic structural diagram of a microfluidic detection system according to an embodiment of the present invention, Figure 3 is a schematic structural exploded view of a microfluidic detection system according to an embodiment of the present invention, Figure 4 is a schematic structural diagram of the internal structure of a microfluidic detection system according to an embodiment of the present invention, Figure 5 : is a schematic structural decomposition diagram of the internal structure of a microfluidic detection system according to an embodiment of the present invention. For ease of understanding, Figures 1 to 5 A sample cup 2 is also shown.

[0058] See also Figures 2 to 5 , the microfluidic detection system 1 may include a microfluidic biochip 10, a chip mounting mechanism 51, a sample liquid driving device 40 and a detection mechanism 20. It can be understood by those skilled in the art that when the preset detection parameters used by the microfluidic detection system are different, the specific selection of the microfluidic biochip 10 and the detection mechanism 20 used by it may also be different. For example, when the microfluidic detection system is used for pesticide residue detection, the microfluidic biochip 10 it has may be a microfluidic biochip 10 that can provide detection conditions for pesticide residue liquid, and the detection mechanism 20 it has may be a pesticide residue detection mechanism that can detect the pesticide residue parameters of the pesticide residue liquid.

[0059] Figure 61 is a schematic cross-sectional view of a microfluidic biochip according to an embodiment of the present invention. The microfluidic biochip 10 has an injection port 111, a communication port 112, and a detection pool 121 formed therein. The injection port 111, the detection pool 121, and the communication port 112 are sequentially connected through a microfluidic channel 14, thereby allowing the sample liquid in contact with the injection port 111 to flow into the microfluidic channel 14 and flow into the detection pool 121 through the microfluidic channel 14. The microfluidic channel 14 involved in the present invention refers to a fine flow channel or capillary flow channel with a flow area within a preset size range so that it has a suitable ability to retain the liquid therein. The injection port 111 and the communication port 112 can be formed at the ends of the microfluidic biochip 10. Further, the injection port 111 and the communication port 112 are preferably formed at different ends of the microfluidic biochip 10.

[0060] The chip mounting mechanism 51 is used to mount the microfluidic biochip 10 to provide support for the microfluidic biochip 10 .

[0061] The sample liquid driving device 40 is sealedly connected to the communication port 112 to force the sample liquid in contact with the injection port 111 to flow into the microchannel 14 and then flow to the detection cell 121 through the microchannel 14, thereby precisely controlling the amount and flow rate of the sample liquid entering the detection cell 121.

[0062] The detection mechanism 20 is used to detect the detection pool 121 to obtain the preset detection parameters of the sample liquid. Specifically, the detection pool 121 may be pre-set with a detection reagent, or the detection reagent may be added to the detection pool 121 manually or automatically, so that the detection pool 121 is detected by the detection mechanism 20 after the sample liquid in the detection pool 121 reacts with the detection reagent therein.

[0063] The refrigerator 100 of the present invention includes a microfluidic detection system 1, and the microfluidic detection system 1 includes a microfluidic biochip 10 for providing detection conditions and a detection environment, a chip mounting mechanism 51 for mounting the microfluidic biochip 10, a sample liquid driving device 40 for accurately controlling the sample liquid to flow into the microfluidic biochip 10, and a detection mechanism 20 for performing a detection operation. The combination of the structure and function of these four modules can not only smoothly perform the injection and detection operations, but also ensure the accuracy of the detection results through the precise control of the injection. On this basis, the structure of each module is very simple, which simplifies the structure of the microfluidic detection system 1 and avoids it from occupying too much space on the refrigerator 100.

[0064] In a specific embodiment, when the detection mechanism 20 is a pesticide residue detection mechanism for detecting the pesticide residue parameters of the pesticide residue liquid, the enzyme inhibition rate method can be used to quickly qualitatively detect whether the pesticide residue in the sample liquid exceeds the standard. At this time, the microfluidic biochip 10 also includes a reaction pool 122 formed inside it, and the reaction pool 122 is located on the main channel formed by the injection port 111, the detection pool 121, and the communication port 112 being connected in sequence, and connected between the injection port 111 and the detection pool 121, so that the sample liquid first reacts with the reaction reagent in the reaction pool 122 and then flows into the detection pool 121. The reaction pool 122 and the injection port 111, and the reaction pool 122 and the detection pool 121 are all connected through the microchannel 14. The reaction reagent and the detection reagent for pesticide residue detection can be an enzyme reagent and a color developer, respectively. The reaction pool 122 is used for the sample liquid to react with the enzyme reagent therein, and the sample liquid after reacting with the enzyme reagent flows into the detection pool 121 and reacts with the color developer in the detection pool 121. The detection mechanism 20 can be selected as a photoelectric detection mechanism, which can include a light source 21 and a photosensitive element 22 respectively arranged on two opposite sides of the microfluidic biochip 10 and facing the detection pool 121. The light emitted by the light source 21 irradiates the detection pool 121, and the light passing through the detection pool 121 is introduced into the photosensitive element 22, so as to facilitate the determination of the absorbance change in the detection pool 121 through the light intensity signal received by the photosensitive element 22, and then calculate the pesticide residue inhibition rate. Furthermore, the detection mechanism 20 also includes a heating plate 24 for providing heat to the detection pool 121 and a temperature controller 25 for controlling the heating power of the heating plate 24 to be constant, so that the sample liquid and the detection reagent in the detection pool 121 react fully and quickly.

[0065] In some embodiments, the sample liquid driving device 40 can be arranged adjacent to the side of the microfluidic biochip 10 in the lateral direction. This ensures the compactness of the structural layout between the microfluidic biochip 10 and the sample liquid driving device 40, and allows the liquid in the microfluidic biochip 10 to flow downward or drip along the microfluidic biochip 10 when leakage or discharge occurs, without contacting the sample liquid driving device 40, thereby avoiding adverse effects on the sample liquid driving device 40.

[0066] Furthermore, the sample liquid driving device 40 may include a driving motor 41 that is suspended. That is, the driving motor 41 is connected to the supporting structure only through its top and does not contact other structures, thereby preventing the vibration generated by the driving motor 41 from being transmitted to the microfluidic biochip 10 or other structures during operation, which not only prevents the stability or performance of the microfluidic biochip 10 or other structures from being adversely affected, but also reduces the vibration of the entire microfluidic detection system 1 and reduces its operating noise. In addition, since the driving motor 41 is used at a high frequency and generates a large amount of heat, the suspended setting of the driving motor 41 also increases the size of the space around it, which is conducive to heat dissipation.

[0067] Specifically, the sample liquid driving device 40 can form negative pressure in the main channel by pumping air outward, so that the sample liquid in contact with the injection port 111 enters the main channel under the action of the negative pressure. Figure 7 1 is a schematic cross-sectional view of a sample liquid driving device and a microfluidic biochip and a structure connected thereto according to an embodiment of the present invention. In some embodiments, the sample liquid driving device 40 may be a micro-injection pump, and further includes a syringe 42, a screw 43, a slider 44 and a piston 45 extending vertically. The syringe 42 is fixed on a bracket 87, and the top of the syringe 42 is sealedly connected to the communication port 112 at the top of the microfluidic biochip 10 through a connecting pipe 46. The screw 43 extends vertically and is connected to the drive motor 41 so as to rotate under the drive of the drive motor 41. The slider 44 is passed through the screw 43 and is threadedly connected to the screw 43 so as to translate up and down along the screw 43 as the screw 43 rotates. The piston 45 is arranged inside the syringe 42 and is fixedly connected to the slider 44 so as to be translated in the up and down directions under the drive of the slider 44, so that when it translates downward, negative pressure is generated in the main channel, thereby prompting the sample liquid in contact with the injection port 111 to flow into the microchannel and then flow into the detection cell 121 through the microchannel, and when it translates upward, it prompts the sample liquid in the main channel to flow toward the injection port 111.

[0068] The sample liquid driving device 40 may further include a position sensor for cooperating with the driving motor 41 to control the displacement of the piston 45 in the upward translation and / or downward translation, thereby realizing precise control of the injection. At the same time, the displacement of the piston 45 in the upward translation and downward translation can be monitored in real time to enable it to perform a subtle push and pull operation, thereby performing a push and aspirate operation in the opposite direction on the sample liquid entering the main channel while ensuring that the sample liquid does not flow out through the connecting port 112, so as to promote the sample liquid in the detection pool 121 to mix more evenly or react more fully with the detection reagent therein, thereby improving the accuracy of the detection result.

[0069] In some embodiments, the sample liquid driving device 40 forms a fluid-tight connection with the communication port 112 through the sealing docking mechanism 90. Figure 7The sealing docking mechanism 90 may include a sealing connector 91 and an elastic pressure member 92. The sealing connector 91 is connected between the microfluidic biochip 10 and the sample liquid driving device 40, and a connection channel penetrating the sealing connector 91 is formed therein. The elastic pressure member 92 is used to apply an elastic force to the sealing connector 91, so that the sealing connector 91 is sealed and docked with the sample liquid driving device 40 and the microfluidic biochip 10 at the same time, so that the sample liquid driving device 40 and the communication port 112 of the microfluidic biochip 10 are sealed and connected through the connection channel inside the sealing connector 91. Thus, an elastic force can be applied to the sealing connector 91 through the elastic pressure member 92 to urge the sealing connector 91 to always maintain a state of being tightly sealed and docked with the sample liquid driving device 40 and the microfluidic biochip 10 at the same time, avoiding the problems of loosening, breaking, etc. that may occur after long-term use due to the use of other docking mechanisms, thereby ensuring a long-term and reliable fluid sealing connection relationship between the sample liquid driving device 40 and the connecting port 112 of the microfluidic biochip 10, and improving the sealing effect between the two.

[0070] In some embodiments, the sample liquid driving device 40 is connected to the communication port 112 via a connecting line 46. The communication port 112 may be formed at the top of the microfluidic biochip 10, and the sample liquid driving device 40 may be disposed adjacent to the side of the microfluidic biochip 10 in the lateral direction to prevent the possible leakage of the microfluidic biochip 10 from causing adverse effects on the sample liquid driving device 40. The connecting line 46 may be connected to the top of the sample liquid driving device 40 to bridge between the sample liquid driving device 40 and the microfluidic biochip 10.

[0071] Further, the sealing connector 91 may include a first connection block 912 for directly docking with the microfluidic biochip 10 and a second connection block 913 disposed on the side of the first connection block 912 away from the microfluidic biochip 10. The first connection block 912 and the second connection block 913, as well as the second connection block 913 and the connection pipeline 46 are sealed by plugging.

[0072] In some embodiments, the elastic pressure member 92 may be a spring, one end of which abuts against a fixed end plate 513, and the other end abuts against the sealing connector 91, and the end plate 513 and the microfluidic biochip 10 are respectively located on opposite sides of the sealing connector 91. Specifically, when the microfluidic biochip 10 is in an installed state, the spring is in a compressed state, thereby generating an elastic force for causing the sealing connector 91 to have a tendency to move toward the microfluidic biochip 10. The number of elastic pressure members 92 may be two or more, so as to increase the magnitude of the elastic force acting on the microfluidic biochip 10, and make the elastic force on the microfluidic biochip 10 more balanced, avoid tilting, and further improve the effect of the sealing connection.

[0073] Furthermore, the sealing docking mechanism 90 further includes a guide rod 93, on which a spring is sleeved to prevent the spring from shifting. One end of the guide rod 93 is fixedly connected to the sealing connector 91, and the other end contacts a Hall switch 94 after the microfluidic biochip 10 is sealed and docked with the sealing connector 91, thereby prompting the Hall switch 94 to generate a trigger signal indicating that the microfluidic biochip 10 is installed in place, so as to prompt the user, thereby avoiding structural damage caused by excessive installation of the microfluidic biochip 10, and also improving the user's experience.

[0074] In order to improve the sealing performance between the sealing docking mechanism 90 and the microfluidic biochip 10, the present application also provides another embodiment of the sealing docking mechanism 90 and the microfluidic biochip 10. Figure 8 is a schematic sectional exploded view of a sealing docking mechanism and a microfluidic biochip according to another embodiment of the present invention, Fig. 9 yes Figure 8 Schematic enlarged view of part A in the middle. Figure 8 The elastic pressure member, guide rod and other structures of the sealing docking mechanism are hidden. In other embodiments, the connection port 112 of the microfluidic biochip 10 of the present invention is also specially fixedly connected with a plug-in needle 15 that protrudes outward, and the internal flow channel 151 of the plug-in needle 15 is sealedly connected with the connection port 112, and the plug-in needle 15 is inserted into the interior of the sealing docking mechanism 90 and forms a fluid-tight connection with the sealing docking mechanism 90. In other words, the sealing docking mechanism 90 is fluid-tightly connected with the sample liquid driving device 40 and the plug-in needle 15 at the same time, realizing a good sealing connection relationship between the sample liquid driving device 40 and the connection port 112 of the microfluidic biochip 10.

[0075] Specifically, the plug-in pin 15 can be plugged into the sealing connector 91 of the sealing docking mechanism 90 . Figure 8 and Fig. 9 The sealing connection 91 in the embodiment shown is Figure 7The structure of the sealing connection member 91 of the embodiment shown in FIG. 1 is slightly different. Figure 8 and Fig. 9 The bottom of the first connection block 912 of the sealing connector 91 in the illustrated embodiment may be provided with a through hole 9121 for inserting the plug pin 15, and the through hole 9121 and the plug pin 15 may be sealed by abutting contact or extrusion contact. The plug pin 15 may be provided with a pinhole 152 for connecting its internal flow channel 151 with the internal fluid of the sealing docking mechanism 90. The pinhole 152 is provided on the section of the plug pin 15 that is inside the sealing docking mechanism 90, that is, the pinhole 152 of the plug pin 15 is inside the sealing docking mechanism 90, which not only ensures a smooth and good fluid connection relationship between the two, but also improves the sealing performance between the two to a great extent, avoiding problems such as air leakage and liquid leakage at the connection between the two.

[0076] Furthermore, in order to prevent the sealing docking mechanism 90 from being damaged after frequent plugging and unplugging of the plug pin 15, the structural strength of the sealing docking mechanism 90 can be improved. However, this requires a high material for the sealing docking mechanism 90, and even if a material with a high structural strength is used, the sealing docking mechanism 90 will still be structurally damaged after a limited number of plugging and unplugging of the plug pin 15. To this end, the applicant of this application improves the structure of the plug pin 15 from another perspective. Fig. 9 The end face 153 of the extended end of the plug-in needle 15 is a continuous and smooth hemispherical surface, and the pinhole 152 of the plug-in needle 15 for fluid communication with the sealing docking mechanism 90 is formed on the circumferential side surface 154 of the section of the plug-in needle 15 located inside the sealing docking mechanism 90. Therefore, when the microfluidic biochip 10 provided with the plug-in needle 15 is sealed and docked with the sealing docking mechanism 90, the contact surface between the plug-in needle 15 and the sealing docking mechanism 90 is a smooth spherical surface, which reduces the friction between the plug-in needle 15 and the sealing docking mechanism 90, so that the sealing docking mechanism 90 will not be scratched or punctured, ensuring that the sealing docking mechanism 90 maintains a good sealing docking function for a long time, improving the service life of the microfluidic detection system 1, and at the same time, reducing the requirements for the structural strength of the sealing docking mechanism 90.

[0077] It should be noted that the extended end of the plug pin 15 refers to the end of the plug pin 15 extending into the sealing docking mechanism 90. Further, the pinhole 152 can be formed on the circumferential side of the section of the plug pin 15 adjacent to its extended end, thereby ensuring the fluid connection between the plug pin 15 and the sealing docking mechanism 90 even if the section of the plug pin 15 inserted into the sealing docking mechanism 90 is not long.

[0078] Further, see Figure 8 and Fig. 9The plugging needle 15 is plugged into the inside of the microfluidic biochip 10 through the communication port 112, and the beginning of the plugging needle 15 extending into the inside of the microfluidic biochip 10 is open to facilitate communication with the microchannel 14, thereby communicating with the communication port 112. The mating interface between the plugging needle 15 and the communication port 112 can be sealed by a sealant 16 to enhance the sealing performance between the plugging needle 15 and the microfluidic biochip 10.

[0079] In some alternative embodiments, the plugging pins 15 may also be integrally formed with the microfluidic biochip 10 .

[0080] In some embodiments, the microfluidic detection system 1 further includes a chip withdrawal mechanism 52, which is used to operably release the support effect of the chip mounting mechanism 51 on the microfluidic biochip 10 to release the microfluidic biochip 10. Thus, the user can release the support effect between the chip mounting mechanism 51 and the microfluidic biochip 10 by operating the chip withdrawal mechanism 52, thereby releasing the microfluidic biochip 10, and the user can easily take out the microfluidic biochip 10 or the microfluidic biochip 10 can fall under its own gravity, which simplifies the user's operation process and improves the user's convenience in replacing the microfluidic biochip 10.

[0081] Furthermore, the chip ejection mechanism 52 can be exposed on the outside of the refrigerator 100, which is convenient for the user to perform the chip ejection operation. No matter how compact the structural layout of the microfluidic detection system 1 itself and its overall structural layout after being integrated into the refrigerator are, it will not affect the disassembly operation of the microfluidic biochip 10, thereby improving the user experience.

[0082] Fig.10 : is a schematic structural diagram of a microfluidic biochip, a chip mounting mechanism, and a chip withdrawal mechanism according to an embodiment of the present invention. In some embodiments, the chip mounting mechanism 51 may include two elastic clamps 511 arranged opposite to each other to apply opposite forces to the microfluidic biochip 10 between the two elastic clamps 511, so that the microfluidic biochip 10 is clamped between the two elastic clamps 511. In addition, the chip withdrawal mechanism 52 is configured to operably apply forces in opposite directions to the two elastic clamps 511 to cause the two elastic clamps 511 to produce elastic deformation in directions away from each other, thereby releasing the clamping effect of the two elastic clamps 511 on the microfluidic biochip 10.

[0083] Specifically, the chip withdrawal mechanism 52 may include a cantilever button 521 suspended on one side of the microfluidic biochip 10 and an abutment block 522 protruding and extending from the inner side of the cantilever button 521 toward the microfluidic biochip 10 and gradually approaching the microfluidic biochip 10, and the abutment block 522 abuts against the inner sides of the two elastic clamps 511 that are arranged opposite to each other, so that when the cantilever button 521 is subjected to a force toward the microfluidic biochip 10, the abutment block 522 applies an outward force to the inner sides of the two elastic clamps 511, thereby causing the two elastic clamps 511 to elastically deform in the outer directions away from each other. In other words, when the microfluidic biochip 10 needs to be disassembled, the user only needs to press the cantilever button 521 to release the clamping effect of the two elastic clamps 511 on the microfluidic biochip 10, thereby releasing the microfluidic biochip 10, which is very easy to operate, and the structure of the chip withdrawal mechanism 52 is very simple and the design is very clever.

[0084] The two opposite side surfaces of the abutment block that respectively abut against the inner sides of the two elastic clamps 511 are inclined toward each other in a direction gradually approaching the microfluidic biochip 10 to ensure the smoothness of the pressing operation of the cantilever button 521 and avoid the occurrence of jamming and other phenomena. Specifically, the abutment block can be roughly in the shape of an isosceles trapezoid, the lower base of the isosceles trapezoid is connected to the cantilever button 521, and the two waists of the isosceles trapezoid are respectively abutted against the inner sides of the two elastic clamps 511.

[0085] In some embodiments, the microfluidic detection system 1 further includes a sample stage 70, which is used to place a sample cup 2, and the sample cup 2 is used to hold a sample liquid. In addition, the sample stage 70 is configured to move in a controlled or operative manner, so that the sample cup 2 placed thereon is transported to a position where the sample liquid in the sample cup 2 is allowed to contact the injection port 111 of the microfluidic biochip 10 through the sample stage 70. Thus, the loading of the microfluidic biochip 10 is achieved. The user only needs to place the sample cup 2 on the sample stage 70, or, after placing the sample cup 2 on the sample stage 70, move the sample stage 70 to a position in contact with the injection port 111 of the microfluidic biochip 10, and the loading operation is very convenient, saving time and effort. In addition, the present application eliminates complex structures such as a sample liquid delivery pump, a delivery pipeline, and a sampling needle by setting the sample stage 70 to be movable, so that the structure of the microfluidic detection system 1 is very simple, thereby avoiding taking up too much space in the refrigerator.

[0086] Further, the microfluidic biochip 10 can be arranged above the sample stage 70, and the injection port 111 is located at the bottom of the microfluidic biochip 10 so that the injection port 111 contacts the sample liquid in the sample cup 2 placed on the sample stage 70. The microfluidic detection system 1 also includes a lifting mechanism 60 for driving the sample stage 70 to move up and down, so that the sample stage 70 switches between a detection position that allows the sample liquid in the sample cup 2 placed on the sample stage 70 to contact the injection port 111 and an initial position at a preset distance below the detection position. In other words, the sample stage 70 can be automatically raised and lowered by the lifting mechanism 60, which further simplifies the user's operation and improves the automation of the microfluidic detection system.

[0087] Fig.11 6 is a schematic structural diagram of a lifting mechanism and a sample stage in a disassembled state according to an embodiment of the present invention. In some embodiments, the lifting mechanism 60 may include a lifting motor 61, a transmission screw 62 and a nut 63. The lifting motor 61 is used to output a driving force. The transmission screw 62 is arranged in a vertical direction and is connected to the output shaft of the lifting motor 61 so as to rotate under the drive of the lifting motor 61. The nut 63 is passed through the transmission screw 62 and is threadedly connected to the transmission screw 62 so as to move up and down along the transmission screw 62 as the transmission screw 62 rotates. The sample stage 70 is fixedly connected to the nut 63 so as to drive the sample stage 70 to move up and down through the nut 63.

[0088] Further, the lifting mechanism 60 also includes a slide rail 64 and a slider 65. The slide rail 64 is arranged on the side of the transmission screw 62 in parallel with the transmission screw 62, and the slider 65 is movably arranged on the slide rail 64. The sample stage 70 is fixedly connected to the slider 65 to guide the sample stage 70 to move up and down through the cooperation of the slide rail 64 and the slider 65. Specifically, when the sample stage 70 moves in the up and down direction under the action of the driving module, the slider 65 is driven to move synchronously. The slider 65 is restricted on the slide rail 64. The slide rail 64 has a guiding and limiting effect on the movement of the slider 65, thereby indirectly guiding and limiting the sample stage 70, avoiding the sample stage 70 from offsetting or jamming during the movement process, and improving the stability of the movement of the sample stage 70. Specifically, the sample stage 70 may include a horizontal connecting plate 74 that is inserted into the transmission screw 62 and fixedly connected to the nut 63, and a vertical connecting plate 75 that extends upward perpendicular to the horizontal connecting plate 74, and the vertical connecting plate 75 is fixedly connected to the slider 65.

[0089] In some embodiments, the lifting mechanism 60 further includes a limit switch 66, which is disposed adjacent to the upper portion of the transmission screw 62, so as to stop the lifting motor 61 when the sample stage 70 moves upward to touch the limit switch 66. In addition, the position of the limit switch 66 is configured so that the sample stage 70 is in its detection position when the lifting motor 61 stops operating under the triggering of the limit switch 66. The sample stage 70 can be kept in its detection position when the lifting motor 61 is not operating. The present application locates the detection position of the sample stage 70 through the limit switch 66, and the positioning is precise, which can avoid the problem that the sample stage 70 continues to move beyond its detection position, resulting in damage to the sample stage 70, the microfluidic biochip 10 and other structures.

[0090] In some embodiments, the sample stage 70 may include a support table 71 and an oscillator 72. The support table 71 is used to support the sample cup 2. Specifically, the support table 71 may be a horizontally placed support plate, and a groove may be provided on the support plate for the bottom of the sample cup 2 to be placed therein, so as to prevent the sample cup 2 from tipping over or shaking during the movement of the sample stage 70, thereby improving the stability of the sample cup 2. The support table 71 is fixedly connected to the horizontal connecting plate 74.

[0091] The oscillator 72 is disposed on the support table 71, and is used to oscillate the sample cup 2 after the sample cup 2 is placed on the support table 71, so that the buffer solution in the sample cup 2 and the sample are fully mixed to produce a sample liquid, so that the substance to be detected on the sample is fully dissolved in the buffer solution to obtain a sample liquid with a suitable concentration. The buffer solution can be pre-set in the sample cup 2 by manual addition, or it can be automatically delivered to the sample cup 2 by a driving device after the sample cup 2 is placed on the sample table 70.

[0092] In some embodiments, the sample stage 70 further includes a weighing sensor 73, which is disposed below the support platform 71 to measure the weight of the sample in the sample cup 2, thereby allowing the buffer driving device 30 to deliver a preset amount of buffer matching the weight of the sample to the sample cup 2. In general, home users extract samples at random, such as tearing off a small piece of vegetable leaves at random. Therefore, in order to ensure the accuracy of the measurement results, the amount of buffer input into the sample cup 2 needs to match the amount of the sample, so that a sample liquid of appropriate concentration can be produced. The present application can automatically and accurately obtain the weight of the sample through the weighing sensor 73 disposed below the support platform 71, thereby automatically controlling the buffer driving device 30 to input a matching amount of buffer into the sample cup 2, which not only ensures the accuracy of the measurement results, but also avoids the inconvenience of use, cumbersome operation, large errors and many other problems caused by the user manually weighing the sample, further improving the automation of the microfluidic detection system and the user experience.

[0093] It should be noted that, in some alternative embodiments, the sample stage 70 may be fixed, and the microfluidic biochip 10 may be movable, which can also facilitate the sampling operation.

[0094] In some embodiments, the microfluidic detection system 1 further includes a buffer bottle 36 and a buffer driving device 30. The buffer bottle 36 is used to contain a buffer. The buffer driving device 30 is connected to the buffer bottle 36 to controllably drive the buffer in the buffer bottle 36 into the sample cup 2 placed on the sample stage 70, so that the buffer is mixed with the sample in the sample cup 2 to produce a sample liquid. Specifically, the buffer bottle 36 is connected to the buffer driving device 30 through an inlet pipe 32. The outlet pipe 31 of the buffer driving device 30 extends to the sample stage 70. This is mainly for the sample to be detected to be a solid sample, and a buffer is needed to dissolve the substance to be detected on the solid sample into it to form a sample liquid; or, the sample is a liquid sample, but the concentration is too high, and it needs to be diluted with a buffer to produce a sample liquid. For example, when performing pesticide residue detection, the sample to be detected is usually a solid food residue such as skin and leaves. The sample needs to be placed in a buffer, and the residual pesticide on the sample is dissolved in the buffer to form a sample liquid.

[0095] Specifically, the buffer driving device 30 can be a peristaltic pump, a diaphragm pump or other suitable types of driving devices. The peristaltic pump or diaphragm pump will generate large vibrations in its radial direction during operation. In order to prevent the vibration from being transmitted to the microfluidic biochip 10, an elastic vibration damper 35 can be provided on the radial outer side of the peristaltic pump or diaphragm pump. The elastic vibration damper 35 can be sleeved on the outside of the buffer driving device 30 and supported in the housing 80 by the clamping action of the bracket 87 and the fixing block 89, and the fixing block 89 can be fixed on the support plate 86.

[0096] In some embodiments, the microfluidic detection system 1 further includes a housing 80, and the chip mounting mechanism 51, the sample liquid driving device 40, the detection mechanism 20 and at least a portion of the microfluidic biochip 10 are all disposed in the housing 80. The housing 80 is provided with a first structural connector 81 for connecting to the box body or door body of the refrigerator 100, and a first electrical connector 82 for forming an electrical connection between the microfluidic detection system 1 and the electrical control device of the refrigerator 100, so as to allow the microfluidic detection system 1 to be installed as a whole to the box body or door body of the refrigerator 100.

[0097] Furthermore, an operating table 83 opened toward the front side is formed on the housing 80, and the sample table 70 is at least partially located in the operating table 83, so that the user can conveniently place and remove the sample cup 2 in the operating table 83. A water receiving box 88 located below the sample table 70 can be provided in the operating table 83 to receive liquid that may drip and avoid contaminating the operating table 83.

[0098] In some embodiments, the microfluidic detection system 1 further includes a circuit board 53, a display device 56 and a switch button 57, wherein the circuit board 53 is disposed in the housing 80 and is electrically connected to the first electrical connector 82 on the housing 80. The electrical components of the microfluidic detection system 1 (such as the lifting mechanism 60, the buffer driving device 30, the sample liquid driving device 40, the detection mechanism 20, the display device 56, the switch button 57, etc.) are all directly or indirectly electrically connected to the circuit board 53. The display device 56 is disposed on the front side of the housing 80 and is electrically connected to the circuit board 53 to display the detection results of the detection mechanism 20. The switch button 57 is disposed on the front side of the housing 80 and is electrically connected to the circuit board 53 to start and / or shut down the detection function of the microfluidic detection system 1. In other words, the user can start, pause or stop the detection function of the microfluidic detection system 1 by operating the switch button 57.

[0099] In some embodiments, the housing 80 may include a rear shell 84 at the rear side and a front panel 85 connected to the front side of the rear shell 84. After the rear shell 84 and the front panel 85 are assembled, a receiving cavity is defined between the two. In addition, a support plate 86 and a bracket 87 are also provided in the receiving cavity of the housing 80. The support plate 86 is fixedly connected to the rear shell 84, and at least part of the structure of the lifting mechanism 60 (such as the non-movable part of the lifting mechanism) and the buffer driving device 30 are fixed on the support plate 86. The bracket 87 is fixedly connected to the front side of the support plate 86, and the microfluidic biochip 10 and the sample liquid driving device 40 are directly or indirectly supported on the bracket 87. Thus, the lifting mechanism 60, the buffer driving device 30, the microfluidic biochip 10 and the sample liquid driving device 40 can be stably supported in the receiving cavity formed between the rear shell 84 and the front panel 85 by the support plate 86 and the bracket 87.

[0100] In some embodiments, the lifting mechanism 60 can be arranged on the side of the sample stage 70 in the horizontal direction, the buffer driving device 30 can be arranged on one side of the microfluidic biochip 10 in the horizontal direction and located above the lifting mechanism 60, the sample liquid driving device 40 is located on the other side of the microfluidic biochip 10 in the horizontal direction, and the buffer bottle 36 is located on the side of the sample liquid driving device 40 away from the microfluidic biochip 10. The microfluidic biochip 10, the sample stage 70, the lifting mechanism 60, the buffer driving device 30, the sample liquid driving device 40 and the buffer bottle 36 after such layout fully utilize the size characteristics of each module in the vertical direction and the horizontal direction, so that the layout of each module is more compact and the occupied space is reduced as much as possible. In addition, the modules are arranged side by side only in the vertical direction and the horizontal direction, and the thickness of the microfluidic detection system 1 in the front-to-back direction is reduced as much as possible, so that it is more suitable for integration in a refrigerator.

[0101] Furthermore, a transversely extending partition 861 may be provided between the buffer driving device 30 and the lifting mechanism 60 to prevent the possible leakage of the buffer driving device 30 from dripping onto the lifting mechanism 60 and affecting the normal operation of the lifting mechanism 60. The partition 861 may be fixed on the support plate 86.

[0102] In some embodiments, the microfluidic detection system 1 is disposed on the door body 300 , which is not only convenient to operate, but also does not occupy the original storage space in the box body 200 , and does not affect the storage capacity of the refrigerator 100 itself.

[0103] Fig.12 301 is a schematic structural exploded view of a door according to an embodiment of the present invention. In some embodiments, the front side of the door 300 has a hollow window 301, and the sample stage 70 of the microfluidic detection system 1 is exposed to the front side of the door 300 through the hollow window 301, thereby allowing the user to place a sample cup on the sample stage 70 without opening the door 300, avoiding the problem of severe cold leakage caused by opening the door 300 for each detection, ensuring the thermal insulation performance of the refrigerator 100, and saving energy consumption.

[0104] Specifically, the door body 300 may include a panel 302 for forming the front part thereof, a door lining 303 for forming the rear part thereof, and a foamed insulation layer (not shown in the figure) disposed between the panel 302 and the door lining 303, and the hollow window 301 is opened on the panel 302. A pre-embedded box 304 is pre-embedded between the panel 302 and the door lining 303 before the foamed insulation layer is formed, and the microfluidic detection system 1 is disposed in the pre-embedded box 304. In other words, the pre-embedded box 304 is pre-embedded between the panel 302 and the door lining 303 before the door body 300 is foamed, and is used to reserve a space between the panel 302 and the door lining 303 for installing the microfluidic detection system 1.

[0105] Furthermore, the embedded box 304 is attached to the rear surface of the panel 302, and the front side of the embedded box 304 is open and faces the hollow window 301, so as to allow the microfluidic detection system 1 to be installed into the embedded box 304 from front to back through the hollow window 301, thereby improving the convenience of installing the microfluidic detection system 1.

[0106] Specifically, the embedded box 304 may be provided with a second structural connector 305 matched with the first structural connector 81 and a second electrical connector 306 electrically connected to the first electrical connector 82, and the second electrical connector 306 is electrically connected to the electric control device of the refrigerator 100. Thus, by providing corresponding structural connectors and electrical connectors on the embedded box 304 and the housing 80, the microfluidic detection system 1 is installed on the door body 300 as a whole, thereby realizing the connection between the entire microfluidic detection system 1 and the refrigerator 100 in terms of structure and circuit. Thus, not only the assembly process of the microfluidic detection system 1 is simplified, but also the disassembly or maintenance of the microfluidic detection system 1 is facilitated.

[0107] The refrigerator 100 of the present application is a refrigerator in a broad sense, which not only includes the so-called refrigerator in a narrow sense, but also includes storage devices with refrigeration, freezing or other storage functions, such as refrigerators, freezers, etc.

[0108] Those skilled in the art should also understand that the terms "upper", "lower", "front", "back", "top", "bottom" and the like used to indicate orientation or positional relationships in the embodiments of the present invention are based on the actual use status of the refrigerator 100. These terms are only used to facilitate the description and understanding of the technical solution of the present invention, and do not indicate or imply that the device or device referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0109] At this point, those skilled in the art should recognize that, although multiple exemplary embodiments of the present invention have been shown and described in detail herein, many other variations or modifications that conform to the principles of the present invention can still be directly determined or derived based on the content disclosed in the present invention without departing from the spirit and scope of the present invention. Therefore, the scope of the present invention should be understood and recognized as covering all these other variations or modifications.

Claims

1. A refrigerator, characterized in that: A microfluidic detection system for qualitatively or quantitatively detecting a preset detection parameter of a sample liquid is included, the microfluidic detection system comprising: A microfluidic biochip, comprising an injection port, a communication port, and a detection pool formed inside the chip, wherein the injection port, the detection pool, and the communication port are sequentially connected through a microchannel; A chip mounting mechanism, used for mounting the microfluidic biochip; a sample liquid driving device, which is sealedly connected to the communication port to cause the sample liquid in contact with the injection port to flow into the microfluidic channel and then flow to the detection cell through the microfluidic channel; and The detection mechanism is used to detect the detection pool to obtain preset detection parameters of the sample liquid.

2. The refrigerator according to claim 1, characterized in that: The sample liquid driving device forms a fluid-tight connection with the communication port through a sealing docking mechanism; and A plug-in needle protruding outward is fixedly provided at the connecting port of the microfluidic biochip, the internal flow channel of the plug-in needle is sealedly connected with the connecting port, and the plug-in needle is inserted into the interior of the sealing docking mechanism and forms a fluid-tight connection with the sealing docking mechanism, and the sealing docking mechanism is fluid-tightly connected with the sample liquid driving device, so that the sample liquid driving device is sealedly connected with the connecting port.

3. The refrigerator according to claim 2, characterized in that: The end surface of the extended end of the plug pin is a continuous and smooth hemispherical surface, and the pinhole of the plug pin for fluid communication with the sealing docking mechanism is formed on the circumferential side surface of the section of the plug pin located inside the sealing docking mechanism.

4. The refrigerator according to claim 1, characterized in that: The microfluidic detection system also includes: The chip ejection mechanism is used to operably release the support effect of the chip mounting mechanism on the microfluidic biochip to release the microfluidic biochip.

5. The refrigerator according to claim 4, characterized in that: The chip mounting mechanism comprises two elastic clamps arranged opposite to each other, so as to apply opposite forces to the microfluidic biochip between the two elastic clamps, so that the microfluidic biochip is clamped between the two elastic clamps; and The chip ejection mechanism is configured to operably apply forces in opposite directions to the two elastic clamps to cause the two elastic clamps to elastically deform in directions away from each other, thereby releasing the clamping effect of the two elastic clamps on the microfluidic biochip.

6. The refrigerator according to claim 1, characterized in that: The microfluidic detection system also includes: A sample table, used to place a sample cup, wherein the sample cup is used to hold a sample liquid; and The sample stage is configured to move in a controlled or operable manner so as to transport the sample cup placed thereon to a position allowing the sample liquid in the sample cup to contact the sample inlet of the microfluidic biochip.

7. The refrigerator according to claim 6, characterized in that: The microfluidic biochip is arranged above the sample stage, and the sample inlet is located at the bottom of the microfluidic biochip; and The microfluidic detection system also includes a lifting mechanism for driving the sample stage to move up and down, so that the sample stage switches between a detection position that allows a sample liquid in a sample cup placed on the sample stage to contact the injection port and an initial position that is a preset distance below the detection position.

8. The refrigerator according to claim 6, characterized in that: The microfluidic detection system also includes: a buffer bottle for containing a buffer; and The buffer driving device is connected to the buffer bottle to controllably drive the buffer in the buffer bottle into the sample cup placed on the sample stage, so that the buffer is mixed with the sample in the sample cup to generate a sample liquid.

9. The refrigerator according to claim 1, characterized in that: The sample liquid driving device is arranged adjacent to the side of the microfluidic biochip in the lateral direction, and comprises a driving motor arranged in the air.

10. The refrigerator according to claim 1, characterized in that: The microfluidic detection system also includes: The sample table is used to place a sample cup, and the sample cup is used to hold the sample liquid; wherein The sample stage includes a support platform for supporting a sample cup and an oscillator arranged on the support platform. The oscillator is used to oscillate the sample cup after the sample cup is placed on the support platform, so that the buffer solution and the sample in the sample cup are fully mixed to produce the sample liquid.

11. The refrigerator according to claim 1, characterized in that: The microfluidic detection system also includes: A housing, wherein the chip mounting mechanism, the sample liquid driving device, the detection mechanism and at least a portion of the microfluidic biochip are all disposed in the housing; and The shell is provided with structural connectors for connecting to the body or door of the refrigerator, and electrical connectors for forming an electrical connection between the microfluidic detection system and the electronic control device of the refrigerator, so as to allow the microfluidic detection system to be installed as a whole to the body or door of the refrigerator.

12. The refrigerator according to claim 1, characterized in that: Also includes: a box body, defining a storage space for storing items therein; and A door body, connected to the box body and used to open and / or close the storage space; in The microfluidic detection system is arranged on the door body.

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