Sample analyzer and sampling method

The automatic removal and installation of the tube cap in the sample analyzer is achieved by using a clamping and cap-removing device, which solves the problem of high resistance caused by the sampling needle piercing the tube cap and improves sampling efficiency.

CN114441790BActive Publication Date: 2026-02-06SHENZHEN REETOO BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202011191813.5
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2020-10-30
Publication Date
2026-02-06
Estimated Expiration
2040-10-30

AI Technical Summary

Technical Problem

Traditional sample analyzers require a sampling needle to pierce a rubber cap during sampling, resulting in high resistance and low sampling efficiency.

Method used

A clamping device is used to move the sample tube to the cap removal and capping device. The cap is then removed from the sample tube and reinstalled, preventing the sampling needle from piercing the cap. This combination of the injection device and the sampling device enables efficient sampling.

Benefits of technology

It improved sampling efficiency, solved the problem of high resistance when the sampling needle pierces the tube cap, and improved work efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present application relates to a kind of sample analyzer and sampling method.Sample analyzer, comprising: sample inlet device;And clamping device, cap removal device and sampling device.Sampling method, comprising the following steps: providing first sample tube, and the first sample tube is capped with tube cap;The components in the first sample tube are mixed;The tube cap is removed from the first sample tube;The first sample tube is sampled, while providing second sample tube, and the second sample tube is capped with tube cap;The tube cap of first sample tube is covered on the first sample tube, while the components in the second sample tube are mixed;The tube cap of second sample tube is removed from the second sample tube;The second sample tube is sampled;The tube cap of second sample tube is covered on the second sample tube.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, in particular to a sample analyzer and a sampling method. BACKGROUND

[0002] In a blood cell analyzer, a component to be measured needs to be sent to a sampling site of the analyzer for sampling, and then a sampling needle of the sampling site sends the sampled component to a main machine of the instrument for related analysis.

[0003] The component to be measured is generally stored in a sample tube. The tube opening of the sample tube is sealed by a tube cap made of rubber material. The traditional sampling device generally mixes the component in the sample tube, and then performs sampling by piercing the tube cap with a sampling needle. In this sampling method, the sampling needle pierces the tube cap with a large resistance, and during the piercing process, the sample tube needs to be subjected to negative pressure, and then sampling is performed. The resistance for lifting the sampling needle is also relatively large, and the sampling efficiency is low. SUMMARY

[0004] Therefore, it is necessary to provide a sample analyzer and a sampling method in view of the above technical problems.

[0005] A sample analyzer comprises:

[0006] a sample feeding device for providing a sample tube, the sample tube being capped with a tube cap; and

[0007] a clamping device, a cap removing and capping device, and a sampling device, the clamping device being used to move the sample tube to the cap removing and capping device, the cap removing and capping device having a sampling site and a cap removing and capping site, the cap removing and capping device comprising a carrying assembly and a cap removing and capping assembly, the carrying assembly being used to carry the sample tube, the carrying assembly being capable of moving from the cap removing and capping site to the sampling site, the cap removing and capping assembly being used to remove the tube cap from the sample tube and to reinstall the tube cap on the sample tube, and the sampling device being used to sample the sample tube from which the tube cap is removed at the sampling site.

[0008] A sampling method comprises the following steps:

[0009] providing a first sample tube, the first sample tube being capped with a tube cap;

[0010] mixing a component in the first sample tube;

[0011] removing the tube cap from the first sample tube;

[0012] sampling the first sample tube, and simultaneously providing a second sample tube, the second sample tube being capped with a tube cap;

[0013] covering the cap of the second sample tube on the second sample tube.

[0014] covering the cap of the second sample tube on the second sample tube.

[0015] sampling the second sample tube.

[0016] covering the cap of the second sample tube on the second sample tube.

[0017] The sample analyzer has the advantages that the sample tube is provided by the sample feeding device, the sample tube is carried in different stations by the clamping device, the cap is first removed from the sample tube by the cap covering and uncovering device, then the sample tube is sampled by the sampling device, and then the cap is installed on the sample tube by the cap covering and uncovering device. Therefore, the sample analyzer does not need to puncture the cap by the sampling needle, solves the problems of needing to apply negative pressure to the sample tube during puncturing, then sampling, and the resistance of the sampling needle is relatively large, and the sampling efficiency is low, and the working efficiency is improved. The sampling method also has the advantage of high working efficiency. BRIEF DESCRIPTION OF DRAWINGS

[0018] Figure 1A FIG. 1 is a structural schematic diagram of a sample analyzer in an embodiment;

[0019] Figure 1B FIG. 2 is a step diagram of a sampling method in an embodiment;

[0020] Figure 2A FIG. 3 is a structural schematic diagram of a sample feeding device in an embodiment;

[0021] Figure 2B FIG. 4 is a top view of the sample feeding device in an embodiment;

[0022] Figure 3A FIG. 5 is a structural schematic diagram of a clamping device in an embodiment;

[0023] Figure 3B FIG. 6 is a working principle diagram of a claw opening assembly in an embodiment;

[0024] Figure 3C FIG. 7 is a structural schematic diagram of the clamping device in an embodiment;

[0025] Figure 3D FIG. 8 is an exploded schematic diagram of the clamping device shown in FIG. 7; Figure 3A

[0026] FIG. 9 is a structural schematic diagram of the clamping device in an embodiment; Figure 3E

[0027] Figure 4A ​Fig. 1 is a perspective view of a mixing device according to an embodiment of the present application;

[0028] Figure 4B Fig. 2 is a side view of the mixing device shown in Fig. 1 ; Figure 4A

[0029] Figure 5A Fig. 3 is a perspective view of a cap removing and capping device according to an embodiment of the present application;

[0030] Figure 5B Fig. 4 is a perspective view of a cap removing and capping assembly according to an embodiment of the present application;

[0031] Figure 5C Fig. 5 is a sectional view of a cap removing and capping mechanism according to an embodiment of the present application;

[0032] Figure 5D Fig. 6 is a perspective view of a carrying assembly according to an embodiment of the present application;

[0033] Figure 5E Fig. 7 is a perspective view of a cap removing and capping device according to an embodiment of the present application. DETAILED DESCRIPTION

[0034] In order to make the above objectives, features and advantages of the present application more clear and comprehensible, specific embodiments of the present application will be described in detail below with reference to the accompanying drawings. In the following description, a lot of specific details are set forth in order to provide a thorough understanding of the present application. However, the present application can be implemented in many different ways other than those described herein, and one of ordinary skill in the art can make similar improvements without departing from the scope of the present application, and therefore the present application is not limited to the specific embodiments disclosed below.

[0035] Figure 1A Fig. 8 is a perspective view of a sample analyzer according to an embodiment of the present application. The sample analyzer comprises a sample feeding device 10, a clamping device 20, a cap removing and capping device 40 and a sampling device 50.

[0036] The sample feeding device 10 is used to provide a sample tube X. The sample tube X fed by the sample feeding device 10 according to an embodiment of the present application can be capped with a tube cap Y or not capped with a tube cap Y. The sample feeding mode of the sample tube X capped with the tube cap Y and the sample feeding mode of the sample tube X not capped with the tube cap Y will be introduced respectively below. For the sample feeding mode of the sample tube X capped with the tube cap Y, the components in the sample tube X can be mixed in the subsequent steps. For the sample feeding mode of the sample tube X not capped with the tube cap Y, in order to prevent the components in the sample tube X from spilling out during the mixing process, the subsequent mixing steps are not performed. First, the embodiment of the sample feeding mode of the sample tube X capped with the tube cap Y will be introduced, and the embodiment of the sample feeding mode of the sample tube X not capped with the tube cap Y will be introduced in detail below.

[0037] The clamping device 20 is used to move the sample tube X to the cap removing and capping device 40, which will be introduced in combination with​Figure 5A The capping and uncapping device 40 has a sampling position 451 and a capping and uncapping position 452. The device includes a support component 42 and a capping and uncapping assembly 43. The support component 42 carries the sample tube X and can move from the capping and uncapping position 452 to the sampling position 451. The capping and uncapping assembly 43 is used to remove the cap Y from the sample tube X and reinstall the cap Y onto the sample tube X. When the sample tube X is in the capping and uncapping position 452, the capping and uncapping assembly 43 removes the cap Y from the sample tube X. Then, the support component 42 moves the sample tube X to the sampling position 451, where the sampling device 50 samples the sample tube X, i.e., aspirates the components within the sample tube X. Afterward, the support component 42 carries the sample tube X back to the capping and uncapping position 452, where the capping and uncapping assembly 43 reinstalls the cap Y onto the sample tube X.

[0038] A sampling method includes the following steps:

[0039] S100. Provide a sample tube X, wherein the sample tube X is covered with a tube cap Y;

[0040] S300, Remove the cap Y from the sample tube X;

[0041] S400, Sample the sample tube X;

[0042] S500, Place the cap Y onto the sample tube X.

[0043] The sampling method described above can be performed using a sample analyzer.

[0044] In S100, sample tube X is provided via injection device 10. In S300, cap Y is removed from sample tube X via cap removal and capping device 40. In S400, sample tube X is sampled via sampling device 50, i.e., the components inside sample tube X are drawn off via sampling device 50. In S500, cap Y is capped back onto sample tube X via cap removal and capping device 40.

[0045] In one embodiment, the sampling method may further include step S200, between steps S100 and S300, mixing the components in the sample tube X. The components in the sample tube X can be mixed using a mixing device 30.

[0046] like Figure 1B As shown, Figure 1BFor a step chart of the sampling method in one embodiment, the sampling method can sample at least the first sample tube and the second sample tube through steps S100, S200, S300, S400 and S500. For example, the first sample tube is sampled according to steps S100, S200, S300, S400 and S500 in sequence, when the sampling of the first sample tube reaches step S400, the sampling of the second sample tube according to steps S100, S200, S300, S400 and S500 in sequence is started, that is, step S400 of sampling the first sample tube and step S100 of sampling the second sample tube are performed simultaneously. When there are other sample tubes X, the above rules can be followed, for example, the third sample tube X is sampled according to steps S100, S200, S300, S400 and S500 in sequence, when the sampling of the second sample tube reaches step S400, step S100 of the third sample tube X is started.

[0047] When the above sampling method is realized by the sample analyzer, that is, during the sampling of the first sample tube, the sampling of the second sample tube is started. The efficiency of sampling is improved.

[0048] One embodiment provides the following sampling method, comprising the following steps:

[0049] A first sample tube is provided, and a tube cap is provided on the first sample tube;

[0050] The components in the first sample tube are mixed;

[0051] The tube cap is removed from the first sample tube;

[0052] The first sample tube is sampled, and a second sample tube is provided, and a tube cap is provided on the second sample tube;

[0053] The tube cap of the first sample tube is covered on the first sample tube, and the components in the second sample tube are mixed;

[0054] The tube cap of the second sample tube is removed from the second sample tube;

[0055] The second sample tube is sampled.

[0056] Of course, the above sampling method also includes the following steps which are continued:

[0057] After the sampling of the second sample tube is completed, the tube cap of the second sample tube is covered on the second sample tube.

[0058] The following embodiments introduce the sample feeding device 10, the clamping device 20, the mixing device 30 and the cap covering device 40 in detail.

[0059] AsFigure 2A As shown, Figure 2A A schematic diagram of the sample injection device 10 in one embodiment is shown. The sample injection device 10 is used to move the sample tube X. For example, at the first station 11, the sample tube X is placed on the sample injection device 10. Figure 2A Sample tube X is not shown in the diagram. Sample tube X can actually be placed in... Figure 2A The sample injection device 10 is configured to move sample tube X to a second station 12 via either a first slot 1041 or a second slot 1042. Specifically, the sample injection device 10 includes a fixing frame 101, a support block 102, and a second injection drive mechanism 103. The second injection drive mechanism 103 connects the fixing frame 101 and the support block 102 to drive the support block 102 to move between the first station 11 and the second station 12. The sample injection device 10 also includes a carrier block 104, which is disposed on the support block 102. Therefore, the support block 102 can carry the carrier block 104 from the first station 11 to the second station 12, and can also carry the carrier block 104 from the second station 12 back to the first station 11. The carrier block 104 has a first slot 1041 and a second slot 1042 for mounting sample tube X. Sample tube X mounted in the first slot 1041 is used for open injection, while sample tube X mounted in the second slot 1042 is used for closed injection.

[0060] It should be noted that when injecting samples into sample tube X with the closed opening, it is usually necessary to shake and mix the components inside sample tube X. When injecting samples into sample tube X with the open opening, it is not necessary to mix the components inside sample tube X to prevent spillage during mixing.

[0061] See also Figure 2A The bearing block 104 is rotatably connected to the support block 102, so that the first slot 1041 and the second slot 1042 can be rotated to the third station 13 respectively. Figure 2A The second slot 1042 is currently located at both the first station 11 and the third station 13. Figure 2A After the bearing block 104 rotates clockwise by a certain angle, the second slot 1042 can be moved away from the third station 13, and the first slot 1041 can be moved to the third station 13.

[0062] like Figure 2B As shown, Figure 2BA top view of the sample injection device 10 in one embodiment is shown. The sample injection device 10 includes a sensing assembly 105 that generates a mixing signal when the second slot 1042 is in the second station 12 and in the third station 13, otherwise, the sensing assembly 105 does not generate the mixing signal. The sample injection device 10 in this embodiment can work with the gripper device 20 and the mixing device 30. Since the sample tube X in the second slot 1042 is closed for injection, for example, the sensing assembly 105 generates the mixing signal when the second slot 1042 is in the second station 12 and in the third station 13, the gripper device 20 moves the sample tube X in the second slot 1042 to the mixing device 30 to complete the mixing process. The sample tube X in the first slot 1041 is not capped Y for injection, and does not need to be mixed, so when the first slot 1041 is in the third station 13, the sensing assembly 105 does not generate the mixing signal, and the sample tube X in the first slot 1041 will not be mixed. The sample injection device 10 in this embodiment can realize the injection of the sample tube X with and without the cap Y, and the injection mode is diverse. At the same time, it can prevent the problem of spilling the ingredients in the sample tube X during mixing caused by mistakenly mixing the sample tube X without the cap Y for injection.

[0063] For example, the sensing assembly 105 can be a micro switch, and the side wall of the carrier block 104 is arc-shaped. When the second slot 1042 is in the second station 12 and in the third station 13, the side wall of the carrier block 104 can touch the micro switch to make the micro switch generate the mixing signal.

[0064] For another example, the sensing assembly 105 can be a sensor, which can generate the mixing signal when the second slot 1042 is in the second station 12 and in the third station 13.

[0065] For another example, the sensing assembly 105 can include a first sensor and a second sensor, the first sensor is arranged on the fixed frame 101, and the second sensor is arranged on the carrier block 104. When the second slot 1042 is in the second station 12 and in the third station 13, the first sensor and the second sensor interact to generate the mixing signal.

[0066] In one embodiment, the sample feeding device 10 comprises a first feeding assembly and a second feeding assembly. The first feeding assembly comprises a first feeding platform for loading a sample rack and a first feeding driving mechanism for driving the sample rack to move to a to-be-picked position in a first direction. The second feeding assembly comprises a second feeding platform for loading a sample tube X and a second feeding driving mechanism 103 connected with the second feeding platform for driving the second feeding platform to move the sample tube X to the to-be-picked position in a second direction. The second feeding platform comprises a support block 102 and a carrying block 104. The support block 102 is connected with the second feeding driving mechanism 103, and the carrying block 104 is rotationally connected with the support block 102 and is provided with at least two loading slots for loading the sample tube X, so that the at least two loading slots can be rotated to the movement track of the second feeding driving mechanism respectively. The loading slot can be, for example, the first slot 1041 and the second slot 1042 shown in the figure. Figure 2B

[0067] As shown in FIG. 1, the second feeding assembly comprises a feeding cabin 107, and the second feeding driving mechanism 103 is arranged inside the feeding cabin 107 to drive the second feeding platform to enter or move out of the inside of the feeding cabin 107. Specifically, the feeding cabin 107 comprises a cabin body 1071 and a cabin door 1072. The cabin body 1071 and the cabin door 1072 are elastically rotationally connected, so that the cabin door 1072 elastically closes the cabin body 1071. The second feeding platform is provided with a pushing wheel, which pushes the cabin door 1072 to open the cabin body 1071 when the second feeding driving mechanism 103 drives the second feeding platform to move out of the inside of the feeding cabin 107.

[0068] In one embodiment, the sample feeding device 10 further comprises an unloading assembly. Figure 2A The structure shown is arranged between the first feeding platform and the unloading assembly, i.e., the fixing frame 101 is arranged between the first feeding platform and the unloading assembly. The first feeding driving mechanism is connected with the first feeding platform and the unloading assembly. The first feeding platform is used to transfer the sample rack to the first feeding driving mechanism, and the sample rack is used to carry the sample tube X. The first feeding driving mechanism is used to transfer the sample rack to the unloading assembly, and the unloading assembly is used to store the sample rack. The path of the first feeding driving mechanism for transferring the sample rack is along Figure 2B the first direction shown,

[0069] In combination with Figure 2A ​The first sample feeding driving mechanism shifts the path of the sample rack, and the path of the support block 102 driven by the second sample feeding driving mechanism 103 to cross each other. It should be noted that the crossing here is in the three-dimensional space, for example, the path of the sample rack shifted by the first sample feeding driving mechanism can be above the path of the support block 102 driven by the second sample feeding driving mechanism 103, or below the path of the support block 102 driven by the second sample feeding driving mechanism 103. It can be understood that the intersection of the two paths is the second working position 12 in the above embodiment. When the sample feeding device 10 works with the clamping device 20, the clamping device 20 can be moved to the position directly above the intersection, so that the clamping device 20 can clamp the sample tube X on the carrier block 104, or clamp the sample tube X on the sample rack.

[0070] It should be noted that the sample rack and the carrier block 104 will not appear at the intersection position at the same time. The sample rack in this embodiment can be multiple, and multiple sample racks can be transferred between the first sample feeding table, the first sample feeding driving mechanism and the unloading assembly in turn, and each sample rack can carry multiple sample tubes X. Therefore, the sample feeding device 10 in this embodiment further enriches the sample feeding mode, which can not only realize Figure 2A the sample feeding shown in the structure, but also realize continuous and large sample feeding through the first sample feeding table, the first sample feeding driving mechanism and the unloading assembly, thereby improving the work efficiency.

[0071] In addition, during the continuous sample feeding process through the first sample feeding table, the first sample feeding driving mechanism and the unloading assembly, for example, in case of emergency, the continuous sample feeding through the first sample feeding table, the first sample feeding driving mechanism and the unloading assembly can be temporarily suspended, and the mechanism composed of the fixed frame 101, the support block 102, the second sample feeding driving mechanism 103 and the carrier block 104 is used for temporary sample feeding.

[0072] For example, when the sample feeding device 10 is applied to the sample feeding of blood samples in a hospital, in the process of realizing continuous sample feeding through the first sample feeding table, the first sample feeding driving mechanism and the unloading assembly, when the blood sample of an emergency patient needs to be temporarily queued, the continuous sample feeding through the first sample feeding table, the first sample feeding driving mechanism and the unloading assembly can be temporarily suspended, the blood sample of the emergency patient is placed on the carrier block 104, and the mechanism composed of the fixed frame 101, the support block 102, the second sample feeding driving mechanism 103 and the carrier block 104 is used for temporary sample feeding.

[0073] The following embodiments respectively introduce the structures of the clamping device 20 and the mixing device 30.

[0074] Figure 3AFig. 1 is a schematic view of a clamping device 20 in an embodiment. The clamping device 20 comprises a clamping jaw frame 21, a clamping jaw assembly 22, a clamping jaw spring 23, and a jaw opening assembly 24. The clamping jaw assembly 22 comprises a first clamping jaw 221 and a second clamping jaw 222 connected to the clamping jaw frame 21. The clamping jaw spring 23 connects the first clamping jaw 221 and the second clamping jaw 222, so that the first clamping jaw 221 and the second clamping jaw 222 have a tendency to close. For example, when the first clamping jaw 221 and the second clamping jaw 222 clamp a sample tube X, the first clamping jaw 221 and the second clamping jaw 222 are first opened, the sample tube X is placed between the first clamping jaw 221 and the second clamping jaw 222, and then the first clamping jaw 221 and the second clamping jaw 222 are driven to close by the clamping jaw spring 23 to clamp the sample tube X.

[0075] As shown in Fig. 2, the first clamping jaw 221 and the second clamping jaw 222 are connected to the clamping jaw frame 21 by a first clamping jaw hinge 211 and a second clamping jaw hinge 212, respectively. The first clamping jaw hinge 211 and the second clamping jaw hinge 212 are connected to the clamping jaw frame 21 by a first clamping jaw hinge spring 213 and a second clamping jaw hinge spring 214, respectively. The first clamping jaw hinge spring 213 and the second clamping jaw hinge spring 214 are connected to the clamping jaw frame 21 by a first clamping jaw hinge spring hinge 215 and a second clamping jaw hinge spring hinge 216, respectively. The first clamping jaw hinge spring 213 and the second clamping jaw hinge spring 214 are connected to the first clamping jaw 221 and the second clamping jaw 222 by a first clamping jaw hinge spring hinge 215 and a second clamping jaw hinge spring hinge 216, respectively. Figure 3B Figure 3B Fig. 3 is a schematic view of the working principle of the jaw opening assembly 24 in an embodiment. The upper drawing is a schematic view of the jaw opening position, and the lower drawing is a schematic view of the jaw closing position. The jaw opening assembly 24 is rotationally connected to the clamping jaw frame 21, and has a long axis and a short axis. When the jaw opening assembly 24 is rotated to the jaw opening position around the clamping jaw frame 21, the end of the jaw opening assembly 24 along the long axis direction drives the first clamping jaw 221 and the second clamping jaw 222 to move away from each other, so that the sample tube X can be placed between the first clamping jaw 221 and the second clamping jaw 222. When the jaw opening assembly 24 is rotated to the jaw closing position around the clamping jaw frame 21, the end of the jaw opening assembly 24 along the short axis direction corresponds to the first clamping jaw 221 and the second clamping jaw 222, so that the first clamping jaw 221 and the second clamping jaw 222 are driven to close by the clamping jaw spring 23, and the first clamping jaw 221 and the second clamping jaw 222 clamp the sample tube X.

[0076] In a conventional clamping device 20, two clamping jaws need to be opened and closed to clamp the sample tube X, so that the two clamping jaws are driven to open and close by a pneumatic cylinder.

[0077] ​The clamping device 20 in the embodiment does not need to use a cylinder, but cooperates the jaw opening assembly 24 and the jaw elastic member 23, that is, the jaw elastic member 23 exerts an elastic force on the first jaw 221 and the second jaw 222 to make them close to each other, and then the jaw opening assembly 24 rotates relative to the jaw frame 21, so that the two ends of the long shaft of the jaw opening assembly 24 abut against the first jaw 221 and the second jaw 222 respectively, so as to make the first jaw 221 and the second jaw 222 move away, that is, the first jaw 221 and the second jaw 222 are pried open, so that the sample tube X can be placed between the first jaw 221 and the second jaw 222. Then the jaw opening assembly 24 rotates relative to the jaw frame 21, and the shaft of the jaw opening assembly 24 abuts against the first jaw 221 and the second jaw 222 respectively, so that the first jaw 221 and the second jaw 222 are pulled together by the jaw elastic member 23 to clamp the sample tube X. Thus, the problems of large impact force, large working noise, large dependence on external air source and inconvenience in use when using a cylinder are overcome.

[0078] It should be noted that the jaw elastic member 23 in the above embodiment connects the first jaw 221 and the second jaw 222, so that the first jaw 221 and the second jaw 222 have a tendency to close to each other, specifically, the parts of the first jaw 221 and the second jaw 222 for clamping the sample tube X close to each other. Similarly, making the first jaw 221 and the second jaw 222 move away is also to make the parts of the first jaw 221 and the second jaw 222 for clamping the sample tube X move away.

[0079] For example, the first jaw 221 and the second jaw 222 can be both slidingly connected to the jaw frame 21. That is, the jaw frame 21 is provided with a sliding groove, and the first jaw 221 and the second jaw 222 are both provided with a sliding block, the sliding block of the first jaw 221 is slidingly connected to the sliding groove of the jaw frame 21, and the sliding block of the second jaw 222 is also slidingly connected to the sliding groove of the jaw frame 21.

[0080] For example, the first jaw 221 and the second jaw 222 can be both slidingly connected to the jaw frame 21. That is, the jaw frame 21 is provided with a sliding groove, and the first jaw 221 and the second jaw 222 are both provided with a sliding block, the sliding block of the first jaw 221 is slidingly connected to the sliding groove of the jaw frame 21, and the sliding block of the second jaw 222 is also slidingly connected to the sliding groove of the jaw frame 21. Figure 3CFor a structural schematic diagram of the clamping device 20 in an embodiment, the first clamping jaw 221 and the second clamping jaw 222 can also be rotatably connected to the clamping jaw frame 21. For example, the first clamping jaw 221 has two ends, a rotating end 223 and a clamping end 224, and the rotating end 223 of the first clamping jaw 221 is rotatably connected to the clamping jaw frame 21. The second clamping jaw 222 also has two ends, a rotating end 223 and a clamping end 224, and the rotating end 223 of the second clamping jaw 222 is rotatably connected to the clamping jaw frame 21. The clamping end 224 of the first clamping jaw 221 and the clamping end 224 of the second clamping jaw 222 are both used to clamp the sample tube X. The clamping jaw elastic member 23 can be a straight spring, and the two ends of the straight spring are connected to the first clamping jaw 221 and the second clamping jaw 222, respectively. The two ends of the long axis of the jaw opening assembly 24 can simultaneously abut the first clamping jaw 221 and the second clamping jaw 222, and the two ends of the short axis of the jaw opening assembly 24 can also simultaneously abut the first clamping jaw 221 and the second clamping jaw 222. Of course, the clamping jaw elastic member 23 can also be a torsion spring or other spring that can provide elastic restoring force.

[0081] Figure 3D For Figure 3A The exploded schematic diagram of the clamping device 20 is shown. The jaw opening assembly 24 includes a driving mechanism and an execution mechanism. The driving mechanism is connected to the clamping jaw frame and the execution mechanism, respectively, to drive the execution mechanism to abut the first clamping jaw 221 and the second clamping jaw 222 during rotation. The execution mechanism includes a long axis end and an end axis end, so that when the driving mechanism drives the execution mechanism to rotate in a forward direction, which can be one of clockwise or counterclockwise, the first clamping jaw 221 and the second clamping jaw 222 are in one of the states of moving away from each other or moving close to each other under the abutting action of the execution mechanism. When the driving mechanism drives the execution mechanism to rotate in a reverse direction, which is opposite to the forward direction, the first clamping jaw 221 and the second clamping jaw 222 are in the other state of moving away from each other or moving close to each other under the elastic force of the clamping jaw elastic member 23.

[0082] In an embodiment, the execution mechanism can include a support seat 241 and at least two guide wheels 242, the support seat 241 is connected to the driving mechanism, and the at least two guide wheels 242 are connected to the support seat 241, respectively, and are arranged in a straight line array, so that the at least two guide wheels 242 form the above-mentioned long axis end in the arrangement direction and form the above-mentioned short axis end in the perpendicular direction to the arrangement direction. For example, the execution mechanism can be a cam.

[0083] In one embodiment, the guide wheels 242 are rotatably connected to the support seat. The support seat 241 is rotatably connected to the jaw holder 21. The long axis and the short axis of the jaw opening assembly 24 can refer to the long axis and the short axis of the support seat 241. The long axis of the jaw opening assembly 24 is used to open the first jaw 221 and the second jaw 222, and the specific process of opening the first jaw 221 and the second jaw 222 can be that the two ends of the short axis of the jaw opening assembly 24 support the first jaw 221 and the second jaw 222, and when the support seat 241 rotates relative to the jaw holder 21, the support seat 241 changes from supporting the first jaw 221 and the second jaw 222 at the two ends of the short axis to supporting the first jaw 221 and the second jaw 222 at the two ends of the long axis. In order to make the above-mentioned rotation process easier, a guide wheel 242 can be arranged at the two ends of the long axis of the support seat 241 respectively, and the first jaw 221 and / or the second jaw 222 are supported by the guide wheels 242. Specifically, when the two ends of the short axis of the support seat 241 support the first jaw 221 and the second jaw 222, the two guide wheels 242 on the support seat 241 support the first jaw 221 and the second jaw 222; when the two ends of the long axis of the support seat 241 support the first jaw 221 and the second jaw 222, one of the guide wheels 242 supports one of the first jaw 221 and the second jaw 222, and the other guide wheel 242 supports the other of the first jaw 221 and the second jaw 222. Of course, in other embodiments, four guide wheels 242 can be arranged, for example, one guide wheel 242 is arranged at each end of the long axis, and one guide wheel 242 is arranged at each end of the short axis.

[0084] As shown in Figure 3D , the jaw holder 21 comprises a jaw holder body 21A and a guide rod 21B connected to the jaw holder body 21A. The first jaw 221 and the second jaw 222 are respectively slidably connected to the guide rod 21B to move away from or close to each other in the guide direction of the guide rod 21B.

[0085] The driving mechanism for connecting the support seat 241 described above can be a jaw motor 243. As shown in Figure 3A , the jaw motor 243 drives the support seat 241 to rotate. The housing of the jaw motor 243 is connected to the jaw holder 21, and the rotating shaft of the jaw motor 243 is connected to the support seat 241. Figure 3D

[0086] In one embodiment, as shown in Figure 3A or Figure 3D ​As shown, the clamping jaw frame 21 is provided with a position sensor 25 for detecting the approaching or separating state of the first clamping jaw 221 and the second clamping jaw 222. The clamping device 20 further comprises a controller which is in signal connection with the position sensor 25 and the clamping jaw motor 243. For example, when the first clamping jaw 221 and the second clamping jaw 222 are in the separating state, the position sensor 25 can sense the first clamping jaw 221 or the second clamping jaw 222, at which time the position sensor 25 sends a signal to the controller, and the controller controls the clamping jaw motor 243 to stop rotating; if it is necessary to make the first clamping jaw 221 and the second clamping jaw 222 approach, the controller controls the clamping jaw motor 243 to rotate by a set angle.

[0087] As shown in Figure 3B , the cross section of the support seat 241 can be oval. Of course, the cross section of the support seat 241 can also be other shapes with a major axis and a minor axis.

[0088] Figure 3E A structural schematic diagram of the clamping device 20 in an embodiment. The clamping device 20 comprises a first moving assembly 26. The first moving assembly 26 comprises a first carrier frame 261, a first guide 262, a first power mechanism 263 and a first transmission member 264. The first guide 262 is arranged on the first carrier frame 261, and the first guide 262 extends along a third direction. In Figure 3E , the third direction can be a vertical direction. The first power mechanism 263 and the first transmission member 264 are both arranged on the first carrier frame 261. For example, the first power mechanism 263 can be a motor, and the first transmission member 264 can be a belt and a belt pulley. The housing of the motor is fixed on the first carrier frame 261, and the belt pulley is rotatably connected to the first carrier frame 261. The belt pulley can have two, and the belt is sleeved on the two belt pulleys. The first transmission member 264 connects the output end of the first power mechanism 263 and the clamping jaw frame 21, i.e. the belt pulley is connected to the rotating shaft of the motor, and the belt is connected to the clamping jaw frame 21. The first power mechanism 263 drives the clamping jaw frame 21 to slide along the third direction on the first guide 262 through the first transmission member 264. The first guide 262 can be a guide rail.

[0089] In an embodiment, as shown in Figure 3E , the clamping device 20 comprises a second moving assembly 27. The second moving assembly 27 comprises a second carrier frame 271, a second guide 272, a second power mechanism 273 and a second transmission member 274. The second guide 272 is arranged on the second carrier frame 271. The second guide 272 can be a guide rail, and the second guide 272 extends along a fourth direction. The fourth direction forms an acute angle or a right angle with the third direction. Figure 3EIn the illustrated embodiment, the fourth direction is horizontal. Both the second power mechanism 273 and the second transmission component 274 are mounted on the second support frame 271. For example, the second power mechanism 273 can be a motor, and the second transmission component 274 can be a belt and pulleys. The motor housing is fixed to the second support frame 271, and the pulleys are rotatably connected to the second support frame 271. There can be two pulleys, and the belt is fitted onto both pulleys. The second transmission component 274 connects the output end of the second power mechanism 273 to the first support frame 261; that is, the pulleys connect to the rotating shaft of the motor, and the belt connects to the first support frame 261. The second power mechanism 273 drives the first support frame 261 to slide along the fourth direction and connect to the second guide component 272 via the second transmission component 274. In other words, the second power mechanism 273 is connected to the first support frame 261 to drive the opening claw assembly 24 to move to a gripping position in the fourth direction. Only after the opening claw assembly 24 has moved to the gripping position can the first power mechanism 263 drive the opening claw assembly 24 to approach the gripping position in the third direction for gripping.

[0090] Figure 4A This is a three-dimensional structural diagram of the mixing device 30 in one embodiment. Figure 4B for Figure 4A Side view of the mixing device 30 shown.

[0091] like Figure 4A and Figure 4B As shown, the mixing device 30 includes a mixing assembly and a clamping assembly. The mixing assembly includes a mixing drive mechanism 32 and a mixing frame 33. The mixing frame 33 has a mixing groove 331 for placing the sample tube X. The fixed end of the mixing drive mechanism 32 is connected to a support frame 31, and the output end of the mixing drive mechanism 32 is connected to the mixing frame 33. The mixing drive mechanism 32 drives the mixing frame 33 to oscillate, thereby mixing the components within the sample tube X. Figure 4B As shown, the mixing drive mechanism 32 may include a mixing motor, the housing of which is fixedly connected to the support frame 31, and the mixing rotation shaft of the mixing motor is connected to the mixing frame 33. The axial direction of the mixing rotation shaft is... Figure 4B As shown by the dashed line OO, the mixing frame 33 can move alternately clockwise and counterclockwise around the mixing rotation axis, that is, around the dashed line OO, so that the mixing frame 33 can be oscillating. For example, the mixing assembly also includes a connector, which connects the mixing frame 33 and the output end of the mixing drive mechanism 32 respectively.

[0092] like Figure 4A and Figure 4BAs shown, the clamping assembly of the mixing device 30 includes a clamping member 35, a mixing elastic member 36, and a stop member 37. The clamping member 35 is movably connected to the mixing frame 33, and the mixing elastic member 36 connects the mixing frame 33 and the clamping member 35, so that the clamping member 35 clamps the sample tube X during the swinging process of the mixing frame 33. The stop member 37 is used to stop the clamping member 35 in the clamping direction, so that when the mixing frame 33 rotates to a preset position, the clamping member 35 releases the sample tube X.

[0093] Furthermore, the mixing frame includes a mixing frame body and a tensioning member 34 connected to the mixing frame body. A clamping member 35 is rotatably connected to the mixing frame 33, and a mixing elastic member 36 connects the tensioning member 34 and the clamping member 35, meaning the mixing elastic member 36 can drive the clamping member 35 to move toward the tensioning member 34. A mixing groove 331 is located between the tensioning member 34 and the clamping member 35, thus the mixing elastic member 36 can cause the clamping member 35 to move toward the mixing groove 331. When a sample tube X is installed in the mixing groove 331, the clamping member 35 can press against the side wall of the sample tube X, thereby pressing the sample tube X into the mixing groove 331.

[0094] Furthermore, such as Figure 4A and Figure 4B As shown, the mixing device 30 also includes a stop 37 connected to the support frame 31. When the mixing drive mechanism 32 drives the mixing frame 33 to swing to a certain position, the stop 37 can support the clamping member 35 and move the clamping member 35 away from the mixing tank 331 to release the sample tube X located in the mixing tank 331. For example, by setting the rotation angle of the rotating shaft of the mixing drive mechanism 32, when the mixing device 30 is in the mixing mode, the rotating shaft of the mixing drive mechanism 32 rotates at a small angle to drive the mixing frame 33 to swing at a small angle around the dotted line OO. At this time, the stop 37 will not collide with the clamping member 35. At this time, the clamping member 35 is held in a state of pressing the sample tube X in the mixing tank 331 by the tension of the mixing elastic member 36. Therefore, in the mixing mode, the sample tube X can be stably held in the mixing tank 331. When the mixing device 30 is in stop mode, the rotating shaft of the mixing drive mechanism 32 rotates at a large angle to a certain position and stops. At this time, the stop member 37 supports the clamping member 35 and pushes the clamping member 35 away from the mixing tank 331 or the tensioning member 34. At this time, the mixing elastic member 36 is stretched, that is, the clamping member 35 is no longer pressing on the side wall of the sample tube X in the mixing tank 331. At this time, the sample tube X can be easily removed from the mixing tank 331. Therefore, when taking the sample tube X into or out of the mixing tank 331, only one hand is needed to hold the sample tube X, which is convenient to use.

[0095] In one embodiment, the mixing device 30 can also not be provided with the tensioning member 34, but the mixing elastic member 36 is directly connected between the mixing rack 33 and the pressing member 35. For example, the mixing elastic member 36 can be a straight spring. In some embodiments, the straight spring can also be replaced by a torsion spring or the like.

[0096] For the embodiment provided with the tensioning member 34, specifically, as shown in Figure 4B the first side 332 of the mixing rack 33 is provided with a second side 333 opposite to the first side 332. The tensioning member 34 is arranged on the first side 332, and the pressing member 35 is arranged on the second side 333.

[0097] As shown in Figure 4A the second side 333 of the mixing rack 33 is provided with a mounting groove 334, and the pressing member 35 is arranged in the mounting groove 334. The mixing groove 331 is communicated with the mounting groove 334, so that the sample tube X can extend into the mounting groove 334. Specifically, the axis of the mixing groove 331 extends in the vertical direction, the pressing member 35 is rotationally connected in the mounting groove 334, and the pressing member 35 can rotate in the mounting groove 334 in the horizontal direction. When the sample tube X is inserted into the mixing groove 331 from the top of the mixing rack 33, the bottom of the sample tube X can extend into the mounting groove 334. Since the pressing member 35 can rotate in the mounting groove 334 in the horizontal direction, when the mixing elastic member 36 provides the contraction force, the pressing member 35 can press on the side wall of the portion of the sample tube X extending into the mounting groove 334, so that the sample tube X is pressed in the mixing groove 331.

[0098] Specifically, the clamping member 35 can be elongated. One end of the clamping member 35 is rotatably connected to the mounting groove 334, and the other end of the clamping member 35 extends out of the mounting groove 334. The portion of the clamping member 35 extending out of the mounting groove 334 can abut against the stop member 37. For example, when sample tube X needs to be inserted into mixing groove 331, mixing drive drives mixing frame 33 to rotate to the maximum deflection angle. It should be understood that mixing drive mechanism 32 can drive mixing frame 33 to rotate to the maximum deflection angle in both clockwise and counterclockwise directions. The maximum deflection angle is specifically when the end of clamping member 35 abuts against stop member 37, and stop member 37 abuts against the end of clamping member 35, causing clamping member 35 to stretch mixing elastic member 36. At this time, clamping member 35 rotates outward from mounting groove 334. Clamping member 35 does not enter mixing groove 331. In the space where mixing groove 331 extends axially, when sample tube X is inserted into mixing groove 331, the bottom of sample tube X enters mounting groove 334, and clamping member 35 will not contact the part of sample tube X inserted into mounting groove 334, so that sample tube X can be easily inserted. When the mixing drive mechanism 32 needs to drive the mixing rack 33 to swing to mix the components in the sample tube X, the mixing drive mechanism 32 drives the mixing rack 33 away from the maximum swing angle. For example, the mixing rack 33 is at the midpoint between the maximum swing angles in the clockwise and counterclockwise directions. During the mixing process, the mixing drive mechanism 32 drives the mixing rack 33 to swing back and forth in a small range in the clockwise and counterclockwise directions relative to the midpoint. That is to say, during the mixing process, the mixing rack 33 will not move to the maximum swing angle. Therefore, the stop 37 will not push the clamping member 35 away. Thus, during the mixing process, the clamping member 35 is always pressed against the side of the sample tube X, firmly pressing the sample tube X in the mixing groove 331.

[0099] In one embodiment, such as Figure 4B As shown, a position sensing component 38 for sensing the position of the mixing rack 33 is provided on the support frame 31. By providing the position sensing component 38, the swing angle of the mixing rack 33 can be accurately determined, facilitating control of the swing angle of the mixing rack 33. For example, the sensing component 105 includes a sensing sensor 382 and a sensing plate 381. The sensing sensor 382 is disposed on one of the support frame 31 and the mixing rack 33, and the sensing plate 381 is disposed on the other of the support frame 31 and the mixing rack 33. The position sensing component 38 can be disposed at the midpoint in the above embodiment, and the sensing plate 381 has a small section in the counterclockwise direction at the midpoint that can be sensed by the sensing sensor 382, ​​and also a small section in the clockwise direction at the midpoint that can be sensed by the sensing sensor 382. During the mixing process, the swing range of the mixing rack 33 is limited to the range within which the sensing plate 381 can always be sensed by the sensing sensor 382.

[0100] In one embodiment, in order to improve the control of the mixing drive mechanism 32 on the swing angle of the mixing rack 33, the mixing drive mechanism 32 can be a stepper motor or a servo motor.

[0101] The sample analyzer in one embodiment includes the sample feeding device 10, the clamping device 20 and the mixing device 30 in the above embodiments, and can further include the cap removing and capping device 40. The sample feeding device 10 is used to feed the sample tube X, the clamping device 20 clamps the sample tube X to the mixing device 30 for mixing, and after the mixing is completed, the clamping device 20 clamps the sample tube X to the cap removing and capping device 40 to remove the cap Y of the sample tube X.

[0102] Figure 5A The cap removing and capping device 40 in one embodiment is shown in the structural schematic diagram. The cap removing and capping device 40 is used to remove the cap Y of the sample tube X, and can also reinstall the removed cap Y on the sample tube X.

[0103] The cap removing and capping device 40 includes a base 41, a bearing assembly 42, a cap removing and capping assembly 43 and a cap removing and capping drive assembly 44. The bearing assembly 42 is arranged on the base 41. The bearing assembly 42 is used to clamp the sample tube X. The cap removing and capping assembly 43 includes a pressing block 431, a lifting block 432 and a connecting plate 433 connecting the pressing block 431 and the lifting block 432. The pressing block 431 and the lifting block 432 are respectively used to press on the two ends of the axial direction of the cap Y. The cap removing and capping drive assembly 44 is connected to the connecting plate 433 to drive the cap removing and capping assembly 43 to move close to or away from the sample tube X located on the bearing assembly 42.

[0104] Specifically, Figure 5A The fifth direction shown can be a vertical direction, and the cap removing and capping drive assembly 44 can drive the cap removing and capping assembly 43 to move upward or downward along the fifth direction. When the cap removing and capping drive assembly 44 drives the cap removing and capping assembly 43 to move upward along the fifth direction, since the lifting block 432 abuts against the lower end of the cap Y and the bearing assembly 42 clamps the sample tube X, the cap Y can be removed from the sample tube X. When the cap removing and capping drive assembly 44 drives the cap removing and capping assembly 43 to move downward along the fifth direction, since the pressing block 431 abuts against the upper end of the cap Y, the cap Y can be pressed downward on the tube opening of the sample tube X, i.e. the cap Y is re-capped on the sample tube X. Therefore, the cap removing and capping device 40 in this embodiment can not only remove the cap Y from the sample tube X, but also reinstall the cap Y on the sample tube X.

[0105] As Figure 5AAs shown, the sixth direction can be a horizontal direction. The cap removing and capping device 40 comprises a moving assembly 46 connected to the base 41 and the carrying assembly 42 to drive the carrying assembly 42 to move along the sixth direction. The moving assembly 46 drives the carrying assembly 42 to slide along the base 41, specifically, the carrying assembly 42 can be slidably connected to the base 41 along the sixth direction. When the carrying assembly 42 slides along the sixth direction, it can move to the sampling position 451 or the cap removing and capping position 452. The cap removing and capping position 452 can be directly below the cap removing and capping assembly 43. When the carrying assembly 42 is at the sampling position 451 or at a position between the sampling position 451 and the cap removing and capping position 452, the sample tube X with the tube cap Y can be installed on the carrying assembly 42. Then the carrying assembly 42 moves to the cap removing and capping position 452 along the sixth direction, and when the carrying assembly 42 moves to the cap removing and capping position 452, the tube cap Y is located between the pressing block 431 and the lifting block 432.

[0106] Figure 5B A perspective view of the cap removing and capping assembly 43 in an embodiment. Figure 5C A sectional view of the cap removing and capping assembly 43 in an embodiment. The connecting plate 433 comprises a side plate 4331 and a top plate 4332, the side plate 4331 connects the top plate 4332 and the lifting block 432, and a space for installing the pressing block 431 is formed between the top plate 4332 and the lifting block 432. The cap removing and capping assembly 43 further comprises a pressing elastic member 435, which can be a straight spring. The pressing elastic member 435 connects the top plate 4332 and the pressing block 431, and is used to push the pressing block 431 towards the lifting block 432. When the tube cap Y is located between the lifting block 432 and the pressing block 431, the pressing force is provided by the pressing elastic member 435, so that the tube cap Y is clamped by the pressing block 431 and the lifting block 432.

[0107] In an embodiment, as shown in Figure 5C The top plate 4332 is provided with a guide hole 43321 penetrating through the thickness of the top plate 4332, and a support step 43322 is arranged in the guide hole 43321. The cap removing and capping assembly 43 further comprises a guide column 434 arranged in the guide hole 43321, the lower end of the guide column 434 extends out of the guide hole 43321 and is connected to the pressing block 431, and the middle part of the guide column 434 is provided with a protruding part 4341 which can be supported on the support step 43322. One end of the pressing elastic member 435 is connected to the top plate 4332, and the other end is connected to the protruding part 4341. When the tube cap Y enters between the pressing block 431 and the lifting block 432, the pressing block 431 moves upwards, driving the guide column 434 to move upwards along the guide hole 43321, so that the protruding part 4341 is separated from the support step 43322, and the pressing elastic member 435 is further compressed.

[0108] In combination Figure 5A And Figure 5C When the cap removing and capping device 40 is to install the tube cap Y on the sample tube X, the cap removing and capping driving assembly 44 drives the connecting plate 433 to press downward in the fifth direction, and when the tube cap Y is installed on the sample tube X, the sample tube X generates an upward pushing force on the tube cap Y to push the downward pressing block 431 upward to compress the downward pressing elastic member 435 together with the guide column 434 and the top plate 4332. At this time, the elastic force of the downward pressing elastic member 435 can control the downward pressing force of the downward pressing block 431 on the tube cap Y, and by selecting a downward pressing elastic member 435 with appropriate elastic force, the tube cap Y can be pressed onto the sample tube X with appropriate downward pressing force. This prevents the tube cap Y from being pressed into the sample tube X with too much force to cause the sample tube X to break or the tube cap Y from being pressed into the sample tube X with too little force to easily come off the sample tube X.

[0109] It should be noted that, as Figure 5A indicated, the connecting plate 433 is connected to the cap removing and capping driving assembly 44, for example, the side plate 4331 or the top plate 4332 of the connecting plate 433 can be connected to the cap removing and capping driving assembly 44.

[0110] As Figure 5B indicated, the upward lifting block 432 is provided with a first accommodating groove 4321 for avoiding the sample tube X, as Figure 5A indicated, the downward pressing block 431 is provided with a guide portion 4311. For example, when the carrying assembly 42 is driven by the moving assembly 46 to enter the cap removing and capping position 452 from the sampling position 451 in the sixth direction, the sample tube X enters the first accommodating groove 4321, the lower end of the tube cap Y is located above the upward lifting block 432, the upper end of the tube cap Y abuts against the guide portion 4311 and lifts the downward pressing block 431 upward in the fifth direction. Thus, the tube cap Y can easily enter between the downward pressing block 431 and the upward lifting block 432.

[0111] In one embodiment, as Figure 5B indicated, the upward lifting block 432 includes a first upward lifting portion 432A and a second upward lifting portion 432B stacked together, the first upward lifting portion 432A is provided with a first accommodating groove 4321 for accommodating the sample tube X, and the second upward lifting portion 432B is provided with a second accommodating groove 4322 for accommodating the tube cap Y. The first accommodating groove 4321 and the second accommodating groove 4322 form a stepped structure 432C, so that the stepped structure 432C is arranged at one end of the tube cap Y in the axial direction.

[0112] Figure 5DA schematic view of a structure of the carrying assembly 42 in one embodiment. The carrying assembly 42 includes a carrying body and a first limiting member 424. The carrying body includes a mounting plate 423, a first carrying member 421 and a second carrying member 422, and the mounting plate 423 connects the first carrying member 421 and the second carrying member 422. For example, the first carrying member 421 and the second carrying member 422 are arranged in a vertical direction, the first carrying member 421 is arranged above the second carrying member 422, and the mounting plate 423 is arranged at a side of the first carrying member 421 and the second carrying member 422. Among them, the mounting plate 423 can have multiple pieces, at least one mounting plate 423 connects the first carrying member 421 and the second carrying member 422, and other mounting plates 423 can be connected to the output end of the moving assembly 46 to drive the carrying assembly 42 to move through the moving assembly 46. Of course, if the mounting plate 423 is arranged in one piece, this piece of mounting plate 423 can be connected to the first carrying member 421, the second carrying member 422 and the output end of the moving assembly 46.

[0113] As shown in Figure 5D The first carrying member 421 is provided with a first limiting hole 4211, and the second carrying member 422 is provided with a second limiting hole 4221, which are used to load different parts of the sample tube X in the axial direction. The sample tube X can be inserted into the first limiting hole 4211 from above, and when the sample tube X is inserted downward, the lower half of the sample tube X can be inserted into the second limiting hole 4221, and when the sample tube X is longer, the first limiting hole 4211 and the second limiting hole 4221 support different parts of the sample tube X in the axial direction, making the installation of the sample tube X more secure.

[0114] Figure 5E A schematic view of a structure of the cap pulling and covering device 40 in one embodiment. The moving assembly 46 is used to drive the carrying assembly 42 to move in the sixth direction. The moving assembly 46 includes a moving driving member 461 and a moving guide assembly 462, and the moving guide assembly 462 connects the base 41 and the carrying assembly 42. It should be noted that the base 41 in this embodiment can have several pieces, which act as carrying members to carry and fix other parts. The moving guide assembly 462 can include a guide rod and a guide block, the guide rod extends in the sixth direction, and the guide block is slidingly connected to the guide rod in the sixth direction. The guide rod is connected to one of the bases 41, and the guide block is connected to the carrying assembly 42. The moving driving member 461 connects the base 41 and the carrying assembly 42 to drive the carrying assembly 42 to slide in the sixth direction. The moving driving member 461 can be a motor and a screw rod connected to the rotating shaft of the motor, as shown in FIG. 5D, one of the mounting plates 423 is connected to a guide block 426, and the guide block 426 is provided with a threaded hole 4261 for screwing the screw rod. As shown in FIG. 1, the included angle between the fifth direction and the sixth direction is less than or equal to 90°.

[0115] See Figure 5D One of the mounting plates 423 is provided with a first limiting member 424, see reference. Figure 5E A second limiting member 425 is provided on the base 41. The first limiting member 424 and the second limiting member 425 are arranged opposite to each other. When the sample tube X is located at... Figure 5A When the cap is removed to position 452, the first limiting member 424 and the second limiting member 425 together clamp the sample tube X. It should be noted that the diameters of both the first limiting hole 4211 and the second limiting hole 4221 are larger than the outer diameter of the sample tube X. When the first limiting member 424 and the second limiting member 425 clamp the sample tube X together, the circumferential position of the sample tube X within the first limiting hole 4211 and the second limiting hole 4221 can be finely adjusted. After fine adjustment, the sample tube X can be located in the middle of both the first limiting hole 4211 and the second limiting hole 4221, making the position of the sample tube X more precise. Figure 5D As shown, the first limiting member 424 is provided with a position correction groove 4241 for accommodating the sample tube X; the position correction groove 4241 can also be provided on the second limiting member 425. The position correction groove 4241 can be a V-shaped groove.

[0116] like Figure 5A As shown, when the first limiting member 424 and the second limiting member 425 clamp the sample tube X together, the cap Y is located between the lower pressing block 431 and the upper lifting block 432, and is held by the lower pressing block 431 and the upper lifting block 432. When the lower pressing block 431 and the upper lifting block 432 move upward along the fifth direction, the cap Y can be pulled off the sample tube X; when the lower pressing block 431 and the upper lifting block 432 move downward along the fifth direction, the cap Y can be closed onto the sample tube X. The cap removal and capping drive assembly 43 can be driven to move up or down along the fifth direction by the cap removal and capping drive assembly 44. The cap removal and capping drive assembly 44 includes a cap removal and capping drive member 441 and a cap removal and capping guide assembly 442. The cap removal and capping guide assembly 442 may include a guide rod and a moving block. The guide rod extends along the fifth direction, and the moving block is slidably connected to the guide rod along the fifth direction. A guide rod can be connected to one of the bases 41, and a moving block is connected to the cap-pulling assembly 43. Specifically, the guide block 426 can be connected to the side plate 4331 of the cap-pulling assembly 43. A cap-pulling drive 441 connects one of the bases 41 and the cap-pulling assembly 43 to drive the cap-pulling assembly 43 to slide in the fifth direction. The cap-pulling drive 441 can be a motor and a lead screw connecting the motor's rotating shaft. A threaded hole for threaded engagement with the lead screw can be provided on the top plate 4332.

[0117] like Figure 5AAs shown in the figure, after the sample tube X on the carrying assembly 42 pulls the tube cap Y off the sample tube X at the cap pulling position 452, the moving assembly 46 moves the sample tube X on the carrying assembly 42 to the sampling position 451 to sample the components in the sample tube X, and after sampling, the moving assembly 46 moves the sample tube X on the carrying assembly 42 back to the cap pulling position 452 to reinstall the tube cap Y on the sample tube X.

[0118] As shown in the figure, the cap pulling device 40 further comprises a positioning assembly 47, which comprises a positioning block 471 connected to the base 41, and when the carrying assembly 42 is at the sampling position 451, the positioning block 471 supports the sidewall of the sample tube X on the carrying assembly 42. Figure 5A As shown in the figure, the positioning assembly 47 further comprises a positioning elastic member 472 connected to the base 41 and the positioning block 471. Figure 5E As shown in the figure, the positioning block 471 is provided with a positioning groove 4711, and when the carrying assembly 42 is at the sampling position 451, the sidewall of the sample tube X abuts against the groove wall of the positioning groove 4711 and compresses the positioning elastic member 472, so as to centrally position the sample tube X and improve the positioning accuracy of the sample tube X.

[0119] The above embodiments only express several embodiments of the present application, and the description is more specific and detailed, but it cannot be understood as the limitation of the scope of the patent. It should be noted that for ordinary skilled in the art, without departing from the concept of the present application, several modifications and improvements can be made, which belong to the protection scope of the present application. Therefore, the protection scope of the patent of the present application should be subject to the appended claims.

Claims

1. A sample analyzer, characterized in that, include: A sample introduction device (10) is used to provide a sample tube (X) covered with a cap (Y); as well as The sample tube (X) is provided with a clamping device (20), a cap removal and capping device (40), and a sampling device (50). The clamping device (20) is used to move the sample tube (X) to the cap removal and capping device (40). The cap removal and capping device (40) has a sampling position (451) and a cap removal and capping position (452). The cap removal and capping device (40) includes a carrying component (42) and a cap removal and capping component (43). The carrying component (42) is used to carry the sample tube (X) and is movable from the cap removal and capping position (452) to the sampling position (451). The cap removal and capping component (43) is used to remove the cap (Y) from the sample tube (X) and reinstall the cap (Y) on the sample tube (X). The sampling device (50) is used to sample the sample tube (X) with the cap (Y) removed at the sampling position (451). The clamping device (20) includes: gripper frame (21); The gripper assembly (22) includes a first gripper (221) and a second gripper (222) both connected to the gripper frame (21); The gripper elastic element (23) connects the first gripper (221) and the second gripper (222); as well as The opening jaw assembly (24) includes a drive mechanism and an execution mechanism. The drive mechanism is connected to the gripper frame (21) and the execution mechanism respectively, so as to drive the execution mechanism to abut against the first gripper (221) and the second gripper (222) during rotation. The execution mechanism includes a long shaft end and a short shaft end, so that when the drive mechanism drives the execution mechanism to rotate in the forward direction, the first gripper (221) and the second gripper (222) are in one of a state of moving away from each other and a state of moving closer to each other under the abutment action of the execution mechanism. When the drive mechanism drives the execution mechanism to rotate in the reverse direction, the first gripper (221) and the second gripper (222) are in the other of a state of moving away from each other and a state of moving closer to each other under the elastic force of the gripper elastic member (23).

2. The sample analyzer according to claim 1, characterized in that, The cap removal and capping assembly (43) includes a lower pressing block (431), an upper lifting block (432), and a connecting plate (433). The connecting plate (433) connects the lower pressing block (431) and the upper lifting block (432). The lower pressing block (431) and the upper lifting block (432) are respectively used to press the cap (Y) at both ends of the axial direction. The cap removal and capping drive assembly (44) is connected to the connecting plate (433) to drive the lower pressing block (431) and the upper lifting block (432) to remove the cap (Y) from the sample tube (X) or to cover the sample tube (X) with the cap (Y).

3. The sample analyzer according to claim 2, characterized in that, The carrier assembly (42) includes a carrier body and a first limiting member (424). The carrier body is used to load the sample tube (X). The first limiting member (424) is connected to the carrier body. The cap removal and capping assembly (43) also includes a second limiting member (425). The second limiting member (425) is used to clamp the sample tube (X) together with the first limiting member (424) when the cap (Y) is removed from the sample tube (X).

4. The sample analyzer according to claim 2, characterized in that, The cap removal and capping drive assembly (44) includes a cap removal and capping drive member (441) and a cap removal and capping guide assembly (442). The cap removal and capping guide assembly (442) is connected to a base (41) and the cap removal and capping assembly (43). The cap removal and capping drive member (441) is connected to the base (41) and the cap removal and capping assembly (43) to drive the cap removal and capping assembly (43) to slide along the fifth direction. The cap removal and capping device (40) further includes a transfer assembly (46) connecting the base (41) and the support assembly (42). The transfer assembly (46) includes a transfer drive (461) and a transfer guide (462). The transfer guide (462) connects the base (41) and the support assembly (42). The transfer drive (461) connects the base (41) and the support assembly (42) to drive the support assembly (42) to slide along a sixth direction. The angle between the fifth direction and the sixth direction is less than or equal to 90°.

5. The sample analyzer according to claim 1, characterized in that, The sample analyzer further includes a mixing device (30), which is used to mix the sample tube (X) before it enters the capping device (40); the mixing device (30) includes: The mixing assembly includes a mixing drive mechanism (32) and a mixing rack (33). The mixing rack (33) is provided with a mixing groove (331) for placing a sample tube (X). The output end of the mixing drive mechanism (32) is connected to the mixing rack (33) and is used to drive the mixing rack (33) to swing to mix the components in the sample tube (X). The clamping assembly includes a clamping member (35), a mixing elastic member (36), and a stop member (37). The clamping member (35) is movably connected to the mixing frame (33). The mixing elastic member (36) connects the mixing frame (33) and the clamping member (35) so that the clamping member (35) clamps the sample tube (X) during the swinging of the mixing frame (33). The stop member (37) is used to stop the clamping member (35) in the clamping direction so that when the mixing frame (33) rotates to a preset position, the clamping member (35) releases the sample tube (X). The sample introduction device (10) includes a sensing component (105). When the second slot (1042) is in the second station (12) and located in the third station (13), the sensing component (105) generates a mixing signal, and the clamping device (20) moves the sample tube (X) in the second slot (1042) into the mixing device (30) to complete the mixing process.

6. The sample analyzer according to claim 5, characterized in that, The mixing frame (33) includes a mixing frame body and a tensioning member (34) connected to the mixing frame body. The mixing groove (331) is located between the tensioning member (34) and the pressing member (35). The mixing elastic member (36) connects the tensioning member (34) and the pressing member (35).

7. The sample analyzer according to claim 5, characterized in that, The mixing frame (33) is provided with a mounting groove (334) communicating with the mixing tank (331), and the clamping member (35) is at least partially disposed in the mounting groove (334) and movably connected to the mixing frame (33).

8. The sample analyzer according to claim 1, characterized in that, The first gripper (221) has a rotating end (223) and a clamping end (224) at its two ends, respectively. The rotating end (223) of the first gripper (221) is rotatably connected to the gripper frame (21). The second gripper (222) has a rotating end (223) and a clamping end (224) at its two ends, respectively. The rotating end (223) of the second gripper (222) is rotatably connected to the gripper frame (21). The clamping ends (224) of both the first gripper (221) and the second gripper (222) are used to clamp the sample tube (X).

9. The sample analyzer according to claim 1, characterized in that, The actuator includes a support base (241) and at least two guide wheels (242). The support base (241) is connected to the drive mechanism. The at least two guide wheels (242) are respectively connected to the support base (241) and arranged in a linear array, such that the at least two guide wheels (242) define the long axis end in the arrangement direction and the short axis end in the direction perpendicular to the arrangement direction. The two ends of the short axis of the support base (241) support the first gripper (22). 1) When the first and second jaws (222) are in position, both guide wheels (242) on the support base (241) support the first jaw (221) and the second jaw (222); when the long shaft of the support base (241) supports the first jaw (221) and the second jaw (222) at both ends, one guide wheel (242) supports one of the first jaw (221) and the second jaw (222), and the other guide wheel (242) supports the other of the first jaw (221) and the second jaw (222).

10. A sampling method, characterized in that, Based on the sample analyzer according to any one of claims 1 to 9, the sampling method includes the following steps: A first sample tube is provided, and the first sample tube is capped. Mix the components in the first sample tube; Remove the cap from the first sample tube; The first sample tube is sampled, and a second sample tube is provided at the same time, the second sample tube being covered with a cap; The cap of the first sample tube is placed on the first sample tube, and the components in the second sample tube are mixed at the same time. Remove the cap from the second sample tube; Sample the second sample tube; Place the cap of the second sample tube onto the second sample tube.

Citation Information

Patent Citations

  • Automated test tube cap removal apparatus

    CN101226204A