System for regulating infusion of a patient and components thereof

Abstract

Various fluid delivery systems are described that include an infusion pump having a housing with a first opening and a hollow interior portion configured to receive a cartridge having a tube. A pump assembly can be disposed within the housing. The pump assembly includes a motor mechanically coupled to a crankshaft or eccentric cam configured to move a set of pistons or other objects to compress one or more portions of the tube over time as the crankshaft or eccentric cam rotates.

Description

[0001] This application claims priority to U.S. Provisional Patent Application No. 63 / 115,443, filed November 18, 2020. The material and all other cited materials are incorporated by reference in their entirety. In the event of inconsistent usages between this document and those documents so incorporated by reference, the usage in the incorporated materials should be considered supplementary to that of this document, and should be substituted therefor. TECHNICAL FIELD

[0002] The technical field is infusion devices, and more particularly, intravenous infusion pumps. BACKGROUND

[0003] The following description includes information that can be useful in understanding the present application. It is not an admission that any of the information provided herein is prior art or relevant to the presently claimed application, or that any publication or document that is specifically or implicitly cited herein is prior art and / or an appropriate baseline for determining prior art. Any publication or other disclosure of comparable prior art in this field is deemed to be incorporated by reference.

[0004] Various pumps exist for infusing patients. One of the most common is a gravity infusion device that utilizes gravity to deliver medication. However, such devices are unable to provide accurate dosage rates and any information about the fluid to be infused.

[0005] To address these issues, many companies have provided volumetric pumps that provide more accurate dosage rates. For example Infusion pumps have been provided that are capable of providing dosage rates for a variety of medications. For example Such pumps are particularly cumbersome, have a limited audience, and can be difficult for patients to access, among other issues.

[0006] All publications identified herein are incorporated by reference herein in their entirety as if each individual publication or patent application were specifically and individually indicated to be incorporated by reference. For contractions between the terminology of a document incorporated by reference and the terminology in this document, the terminology in this document controls, and the terminology in the incorporated reference is inapplicable.

[0007] Accordingly, there remains a need for improved infusion devices that are convenient to use, easy to operate, easy to access, and provide protection against medication stoppage and other accidents. SUMMARY

[0008] The present invention provides apparatuses, systems, and methods for intravenous (IV) infusion devices. Consider a fluid delivery system that includes a housing having a first opening connected to a hollow interior portion. The first opening and the hollow interior portion are configured to receive at least a portion of a tubing set

[0009] It is contemplated that the tubing set includes a housing configured to retain a portion of tubing through which medication can flow from a source of medication to a patient.

[0010] The pump unit operates within the housing and is comprised of a motor. The motor is mechanically coupled to the eccentric cam via one or more gears, such that the motor causes rotation of the eccentric cam. The eccentric cam is preferably connected or coupled to one or more pistons configured to move as the eccentric cam rotates. When the cartridge is disposed at the hollow interior portion, the tubes of the cartridge are disposed proximate or adjacent to the pump unit, such that rotation of the eccentric cam causes the pistons to depress different portions of the tubes over time, thereby causing the liquid within the tubes to flow at a flow rate based on the rotation of the eccentric cam.

[0011] It is contemplated that the envisioned infusion system preferably further includes a display in communication with the pump unit and configured to display infusion information related to the patient and the medication. The display is preferably a touch screen display or otherwise configured to allow for input of commands from a medical professional. For example, using the display, a medical professional can consider the dosage of medication to be provided to the patient.

[0012] It is preferable that the display is physically separate from the housing and is communicatively coupled to the pump unit, either wired or wirelessly. In such embodiments, it is preferable that the display is attachable or otherwise coupled to the IV pole and is configured at eye level of the user. To allow for ergonomic use, it is contemplated that the display can be moved vertically up and down the IV pole until a desired height is reached. The display can also be rotated on the IV pole. In some contemplated embodiments, the display can be tilted up and / or tilted down to facilitate viewing of information on the display.

[0013] In certain embodiments, the tubes can enter the top of the barrel housing and exit through the bottom of the barrel housing. It is preferable, although not necessary, that the tubes enter and exit through the front face or barrel face (e.g., the face of the barrel interior portion facing outward) of the barrel housing. In certain embodiments, the portion of the barrel extending generally horizontally can be disposed at an angle greater than zero degrees from horizontal, meaning that as the tubes move from the front of the housing to the back of the housing, the tubes move at a lower position relative to the barrel face. This can help to cause any air bubbles within the tubes to flow upward (e.g., toward the front of the housing) and out of the barrel.

[0014] The barrel is preferably coupled to a vent valve by the actuator that prevents the flow of liquid within the tubes. The vent valve is configured with a compression tube to prevent the flow of liquid within the barrel when the vent valve is in a first position. This can help to prevent the inadvertent flow of liquid through the barrel. It is preferable that the vent valve is biased in the first position, such as by a spring, to prevent the flow of liquid when the actuator is not in operation.

[0015] When the actuator is depressed or activated, the vent valve moves to the second position, allowing liquid to flow through the cylinder. Preferably, the actuator is positioned on the outer surface of the cylinder shell and extends outwards. In some embodiments, the actuator may be slightly protruding, so that inserting the cylinder into an intravenous (IV) delivery system will depress the actuator when the cylinder is inserted into the delivery system.

[0016] Imagine an infusion pump that comprises one or more sensors to provide various information to the pump, display, control unit, or other devices. For example, other components of the pump unit or device may include one or more sensors that monitor the flow rate of the liquid within the tubing. In another example, the pump unit may include one or more sensors that can be used to determine or measure the characteristics of the liquid within the tubing, such as the drug concentration, drug type, or other liquid. Such sensors may include other sensors such as chemical sensors, optical sensors, and resistive sensors.

[0017] The various objects, features, aspects and advantages of the invention will become more apparent in the following more and more specific detailed description and in the accompanying drawings (where numbers are indicated as components). Attached Figure Description

[0018] Figure 1A An embodiment of a liquid transfer system flowchart is shown.

[0019] Figure 1B An embodiment of the liquid transfer system is shown.

[0020] Figure 2 An embodiment of the infusion pump and display is shown.

[0021] Figure 3 Another embodiment of the infusion pump and display is shown.

[0022] Figure 4 Another embodiment of the infusion pump and display is shown.

[0023] Figure 5 Another embodiment of the infusion pump and display is shown.

[0024] Figures 6A-6D An embodiment of the locking mechanism of an infusion pump is shown.

[0025] Figures 7A-7B Another embodiment of the locking mechanism of the infusion pump is shown.

[0026] Figure 8 An embodiment of an infusion pump housing is shown.

[0027] Figure 9A It shows Figure 8 The filter element and the vent valve are in the closed position.

[0028] Figure 9B It shows Figure 8 The filter element has its vent valve in the open position.

[0029] Figure 10 Another embodiment of the infusion system is shown.

[0030] Figure 11 Another embodiment of the infusion system is shown.

[0031] Figures 12A-12C The lights were illuminated in green, yellow, and red respectively. Figure 11 Infusion system

[0032] Figures 13A-13B Another embodiment of a pump unit for an infusion pump is shown.

[0033] Figures 14A-14B Another embodiment of a pump unit for an infusion pump is shown.

[0034] Figure 15A Another embodiment of an infusion pump is shown in cross-sectional view.

[0035] Figure 15B It shows Figure 15A Amplification section of the infusion pump.

[0036] Figures 16A-16B Another embodiment of an infusion pump is shown in cross-sectional view.

[0037] Figure 16C It shows Figure 16B Amplification section of the infusion pump.

[0038] Figure 16D An example of an exploded view of a piston and rod used in a pump assembly is shown.

[0039] Figure 16E It shows Figure 16D Assembly diagram of the piston and tie rod.

[0040] Figures 16F-16G A side view of one embodiment of the actuator and cylinder vent valve is shown. Detailed Implementation

[0041] In the following discussion, extensive reference will be made to servers, services, interfaces, portals, platforms, or other systems composed of computing devices. It should be recognized that the use of such terms is deemed representative of one or more computing devices. The devices are configured with at least one processor to execute software instructions stored on a computer-readable tangible, non-transitory medium. For example, a server can include one or more computers operating as a web server, database server, or other type of computer server to fulfill the roles, responsibilities, or functions described.

[0042] The following discussion provides numerous example embodiments of the present application. While each embodiment represents a single combination of the inventive elements, the inventive subject matter is considered to include all combinations of the disclosed elements. Thus, if one embodiment comprises elements A, B, and C, and a second embodiment comprises elements B and D, then the inventive subject matter is also considered to include other remaining combinations of A, B, C, or D even if not explicitly disclosed.

[0043] Figure 1A One embodiment of a fluid delivery system 100 flow diagram is shown. The system 100 preferably includes an infusion pump 102 in communication with a display screen 104, which is preferably separate from the pump 102. The infusion pump 102 preferably receives information regarding one or more vital signs of a patient 112 from one or more sensors 106. Such information can be received directly from the one or more sensors 106 or through an intermediary device, such as a patient monitor 108.

[0044] The infusion pump 102 preferably regulates a medication 110 or other fluid through the pump 102 to control the rate of flow of the medication 110 and other fluid delivered to the patient 112. The pump 102 preferably receives electrical power from a voltage line 114, however, it is contemplated that the pump 102 can have a backup battery to continue regulating fluid flow if the power to the infusion pump 102 is shut off or temporarily disconnected.

[0045] In some embodiments, the display screen 104 and the infusion pump 102 can both be mounted on or otherwise connected to a pole 118.

[0046] Figure 1BOne embodiment of a liquid delivery system is shown that includes an infusion pump 102 in communication with a display 104. More preferably, the display 104 can be separate from the pump 102. The infusion pump 102 is preferably receiving information about one or more vital signs of a patient 112 from one or more sensors, which can be monitored by a patient monitor 108 or another intermediary device. In other embodiments, the sensors can transmit information directly to the infusion pump 102. Contemplated sensors can include, for example, a pressure sensor, a thermometer, a heart rate monitor, a blood oxygen monitor, etc. Using the display, a medical professional 114 can input commands or view information about the patient 112 and / or the delivery of medication, for example.

[0047] The infusion pump 102 is preferably regulating medication 110 or other liquid such as from an IV bag through the infusion pump 102 and to the patient 112. More preferably, the infusion pump 102 controls the flow rate of the medication 110 or other fluid through a tube 109, thereby controlling the amount of medication 110 or other fluid delivered to the patient 112 over a particular time period. In some embodiments, both the display 104 and the infusion pump 102 can be mounted to or otherwise connected to a pole 118.

[0048] Figure 2 One embodiment of an infusion pump 202 is shown that includes a housing 204 configured to receive a cartridge 206 and having a tube 208. The infusion pump 202 preferably includes a controller having a processor and a memory, wherein the memory is configured to store one or more control algorithms. The controller is configured to control a motor of the pump unit, thereby regulating the flow of fluid through the tube 208 within the cartridge 206. In certain embodiments, the controller can be configured to control a lockout mechanism, such as one or more solenoids to release the cartridge 206.

[0049] A display screen 210 is in communication with the infusion pump 202, displaying information about the medication delivered to the patient and other vital signs information of the patient. The display screen 210 is preferably comprised of a touch screen display or a technology that allows one or more commands to be input by touching the display 210 or otherwise interacting with the display 210. Of course, it is contemplated that commands can be input by other methods, such as by voice, keyboard, mouse, or other input device. In this manner, it is contemplated that commands can be received at the display 210 and transmitted from the display 210 to the infusion pump 202.

[0050] Each display 210 is preferably separate from the infusion pump 202 and mechanically coupled to the pole 220 so that both the display 210 and the infusion pump 202 can be mounted to the pole 220. The mounting arrangement preferably allows the display 210 and the infusion pump 202 to be moved vertically along the pole 220 to adjust the height relative to the floor or other surface. In some embodiments, the mounting arrangement of the display 210 also allows for angular adjustment so that the display 210 can be rotated and / or tilted to the pole 220.

[0051] In some embodiments, the display 210 can be secured by a base 212 that is mechanically coupled to the pole 220. In this manner, the display 210 is removably coupled to the base 212, e.g., the display 210 can be removed from the base 212 and held by a medical professional or other user. It is contemplated that the base 212 can include one or more connections that provide power and wired data connections to the display 210 when the display 210 is inserted into the base 212.

[0052] Rather than including a control unit (controller) in the housing of the infusion pump 202, it is contemplated that the infusion pump 302 can be in communicative connection with a control unit 330 in the housing, as shown in Figure 3 Similar to the above, the control unit 330 preferably includes a processor and a memory, where the memory is configured to store one or more control algorithms. The control unit 330 is in communicative connection with the infusion pump 302 (directly or indirectly through a wired or wireless connection) to control the infusion pump 302. In some embodiments, the control unit 330 can control multiple infusion pumps, each of which can regulate the flow of a different medication fluid.

[0053] The control unit 330 is configured to control the pump unit and / or motor of the infusion pump 302 to regulate the flow of the liquid disposed within the pump 302 within the tubing 308 within the barrel 306. In some embodiments, the control unit 330 can be configured to control a locking mechanism, e.g., one or more solenoids, to release the barrel in accordance with commands from the controller. A more detailed discussion of an exemplary locking mechanism is provided below. With respect to the remaining numerals in Figure 3 the same considerations apply for the same components having the same numerals as in Figure 2 .

[0054] Figure 4The control unit 430 is shown to be communicatively connected to four infusion pumps 402A-402D. Similar to the above, the control unit 430 includes a processor and memory, wherein the memory is configured to store one or more control algorithms. The control unit 430 is configured to control each infusion pump 402A-402D, specifically, each infusion pump is motorized as 402A-402D, to regulate the fluid flow rate within cartridges 406A-406D inserted within each infusion pump 402A-402D. In some embodiments, the control unit 430 may be configured to control a locking mechanism, such as one or more solenoids, to release cartridges 406A, 406B, 406C, or 406D disposed within one of the infusion pumps 402A-402D.

[0055] The control unit described herein with respect to various embodiments, whether located inside or outside the infusion pump, can be configured to receive signals and / or information and send command signals. For example, the control unit can be configured to receive signals and / or information about one or more vital signs of a patient and, based on the received information, change the drug dosage rate to the patient. For example, this can be achieved by the control unit increasing or decreasing the RPM of the motor in the pump unit based on one or more algorithms and / or one or more variables, limitations, or factors stored in the control unit's memory, such as by changing the motor voltage.

[0056] and Figure 2 The infusion pumps shown are the opposite, wherein the pump has an opening on its forward-facing surface to receive a cartridge, and each of the infusion pumps 402A-402D has an opening on its top surface, which is configured to receive cartridges 406A-406D respectively. Regarding Figure 4 The remaining numbers in the same way apply to those with the same characteristics. Figure 2 The same components with the same number.

[0057] Figure 5 Another embodiment of the infusion pump 502 is shown, comprising a housing 504 having a first opening 505 and a hollow interior portion. Preferably, a cylinder 506 can be inserted into the first opening 505 and at least partially into the hollow interior. The cylinder 506 preferably includes a portion of a tube 508, which can be connected at one end to a fluid source 540 and at the other end to a patient. When the cylinder 506 is inserted into the housing 504, the cylinder is preferably held within the housing 504 using one or more latching mechanisms, wherein the latching mechanisms are described below.

[0058] The infusion pump 502 may optionally include a handle 550 to facilitate carrying the infusion pump 502. In some embodiments, when the cable is not in use, the power cable for the infusion pump 502 may be wrapped around the handle 550. In other embodiments, the cable may be wrapped around the foot 552 of the infusion pump 502 when not in use.

[0059] The display 510 can be communicatively coupled with the infusion pump 502 by a wired or wireless connection and configured to display on a display screen of the display 510 display information regarding the flow of medication to the patient and information regarding one or more vital signs of the patient. Preferably, the display 510 has a touch screen or other technology to allow input of one or more commands by touching the display 510 or otherwise interacting with the display 510. In this manner, it is contemplated that commands can be received at the display 510 and then transmitted from the display 510 to the infusion pump 502. In Figure 5 In the illustrated embodiment, it is contemplated that the infusion pump 502 includes a control unit disposed within the housing 504 and configured to control a pump unit also disposed within the housing 504. An exemplary pump unit is described in greater detail below.

[0060] Preferably, each of the display 510 and the infusion pump 502 can be separable from one another and mechanically coupled to the pole 520 such that both the display 510 and the infusion pump 502 can be mounted or otherwise connected to the pole 520. The preferred mounting arrangement allows the display 510 and the infusion pump 502 to be moved vertically along the pole 520. In some embodiments, the mounting arrangement of the display 510 can allow for angular adjustment such that the display 510 can be tilted and / or rotated relative to the pole 520. In such embodiments, the display 510 and the infusion pump 502 can thus be adjusted to a desired height of the medical professional 560.

[0061] In some embodiments, the display 510 can be secured in place by a base 512 that is mechanically coupled to the pole 520. In this manner, the display 510 can be removably connected to the base 512 such that the display 510 can be removed and hand-held, for example, by a user.

[0062] Additionally or alternatively, it is contemplated that the display 510 can be hingedly coupled to the infusion pump 502 such that the display 510 can be rotated and / or tilted relative to the infusion pump 502. In alternative embodiments, for example, it is contemplated that the infusion pump 502 can have a slot or other mechanism to receive a portion of the display 510 such that the display 510 can be secured to the pump 502 during transport.

[0063] With respect to the remaining numerals in Figure 5 the same considerations apply to the same components having the same numerals of Figure 2 .

[0064] Figures 6A-6DOne embodiment of a latching mechanism 640 including a latching solenoid is shown, which is configured to engage a bore or recess / indentation / depression 607 of a cartridge 606 when the cartridge 606 is properly positioned within a housing 604 of an infusion pump 602, where the cartridge 606 has a conduit 608. Preferably, the latching mechanism 640 is a pull solenoid that is biased in a first position Figures 6A-6B shown in a first position, where a protrusion of the latching mechanism 640 is disposed within the bore or recess / indentation / depression 607 of the cartridge 606. Preferably, the cartridge 606 has a curved or tapered upper surface, and optionally a curved or tapered bottom surface, such that the latching mechanism 640 is depressed when the cartridge 606 is inserted and until the latching mechanism 640 moves into the bore or recess / indentation / depression 607 of the outer surface of the cartridge 606.

[0065] As shown in Figures 6A-6D the latching mechanism 640 can be mechanically connected to an emergency release 642, which can be concealed by a cover 644 on the outer surface of the housing 604 when not in use. The emergency release 642 can be advantageously used to change the position of the latching mechanism 640 to the position shown in Figure 6C thereby releasing the cartridge 606 when the latching mechanism 640 is not functioning, for example due to a power outage or malfunction. In some embodiments, the emergency release 642 includes a metal component with a snap ring that, when pulled, releases the engagement of the latching mechanism 640 with the cartridge 606, for example as shown in Figure 6C

[0066] Figures 7A-7B Another embodiment of an infusion pump 702 is shown, having a housing 704 into which a cartridge 706 can be inserted. As described above, the pump 702 can include a motor 750 connected to and driving a pump assembly 752 for causing and regulating fluid flow within a conduit 708 of the cartridge 706.

[0067] The infusion pump 702 can include one or more latching mechanisms 740 configured to prevent the cartridge 706 from being inadvertently removed from the pump 702. A preferred latching mechanism 740 includes a locking solenoid configured to engage a recess or indentation 707 of the cartridge 706 when the cartridge 706 is properly disposed within the housing 704 of the infusion pump 702. Preferably, the latching mechanism 740 is a pull solenoid that is biased in a first position Figure 7A shown in a first position, where a protrusion of the latching mechanism 740 is engaged with the indentation 707 in the cartridge 706 sidewall. As Figures 7A-7B ​As shown, preferably, the housing 704 of the infusion pump 702 includes two latching mechanisms 740 disposed on the left and right sides of the housing 704. In this way, each of the latching mechanisms 740 engages with a recess or notch 707 on the left and right sides of the cylinder 706 when the cylinder 706 is properly inserted into the housing 704.

[0068] As mentioned above Figures 6A-6D The latching mechanism discussed here is conceivable, and each latching mechanism 740 may have an emergency release device, such as the emergency release device described above, to ensure that the cylinder 706 can be manually released from the housing 704 if necessary.

[0069] Figure 8 An embodiment of a cylinder 806 having a housing 809 and a tube 808 is shown, wherein a portion of the tube 808 extends through the cylinder 806 to form a C-shape. As shown, the housing 809 may include recessed or recessed regions 807 located on the left and right sides of the housing 809, both of which are configured to receive part of a latching mechanism, such as those described herein.

[0070] In some embodiments, the left and right sides of the housing 809 may include recessed regions 811 leading to a notch or recessed region 807, thereby keeping the latching mechanism disengaged until the latching mechanism is located in the notch or recessed region 807.

[0071] like Figure 8 As shown, the tube preferably remains flat at the rear of the cylinder 806, such that when the cylinder 806 is properly inserted into the housing of the infusion device, the tube at the rear of the cylinder 806 is pressed against the pump unit. The tube 808 preferably enters and exits through the front surface of the cylinder 806 and is wound around to form a C-shape.

[0072] Cylinder 806 also includes a valve 820 that facilitates filling of cylinder 806. Valve 820 may include a vent valve, for example, which may be actuated by a push-button or pull tab. When valve 820 is in a first position, conduit 808 may be compressed to prevent fluid from flowing through the conduit. When valve 820 is in a second position, conduit 808 is depressurized, allowing fluid to flow through conduit 808, for example, to fill the conduit.

[0073] In some embodiments, the outer casing 809 is preferably transparent or translucent to allow light to be emitted through the casing 806.

[0074] Figure 9A The cylinder 806 is shown with valve 820 in the first position (the tube is compressed). Figure 9B The cylinder 806 shows valve 820 in the second position (pipe pressure reduction).

[0075] In alternative embodiments, an actuator connected to the valve can be used, where the actuator includes a button to move the valve from the first position (closed) to the second position (open) when the actuator is pressed. It is contemplated that the valve can include a hook disposed around the tubing, as described below and shown in Figures 16F-16G

[0076] Figure 10 A fluid delivery system 1000 of an infusion pump is shown, which includes a pump unit 1002 disposed within a housing of the infusion pump. Preferably, the infusion pump is configured to receive a cartridge 1004 having a tubing 1006 extending through the cartridge 1004 to form, for example, a C-shape. When the cartridge 1004 is inserted into the housing of the infusion pump, the tubing 1006 on the back of the cartridge 1004 is pressed against a portion of the pump unit 1002.

[0077] As shown, the pump unit 1002 includes a variable speed motor 1008 that is mechanically connected to an eccentric cam 1012 via a set of gears 1010. In this manner, the motor 1008 causes rotation of the cam 1012. Preferably, the cam 1012 includes a single injection molded piece to reduce overall wear of the cam 1012 over time. The cam 1012 preferably includes a plurality of discs or pulleys 1013 disposed on a shaft of the cam 1012, where at least some of the discs or pulleys 1013 are disposed on the shaft such that a center of the discs or pulleys 1013 is offset from a center of the shaft of the cam 1012. It is contemplated that the cam 1012 can be modular and replaceable, which allows the pump unit 1002 to be easily serviced during the useful life of the pump unit 1002.

[0078] The cam 1012 is preferably disposed adjacent to one or more pads 1014 that sequentially press against the tubing 1006 as the cam 1012 rotates and the pulleys 1013 contact the pads 1014. When the pads 1014 are pressed against the tubing 1006 and then released, fluid can be caused to flow within the tubing 1006. The higher the frequency at which the pads 1014 are pressed against the tubing 1006 and then released within a predetermined period of time, the greater the flow rate of fluid through the tubing.

[0079] ​The fluid delivery system 1000 preferably includes a latching mechanism 1020 that secures the cartridge 1004 within the housing of the infusion pump when the latching mechanism 1020 is engaged with the cartridge 1004. Preferably, the latching mechanism includes a pull solenoid that engages with the notches or recessed areas on the left and right sides of the cartridge 1004 as described above.

[0080] In some embodiments, the cartridge 1004 includes left and right notches that facilitate a user grasping the cartridge 1004.

[0081] Figure 11 Another embodiment of a fluid delivery system 1100 of an infusion pump is shown having a light source 1130 that can be used to illuminate the cartridge 1104, for example. In this way, the light source 1130 can be used to visually indicate the status of the fluid delivery system 1100 when an alert is generated, an alarm is sounded, and attention to the system is required.

[0082] Figures 12A-12C The cartridge illuminated by the light source within the fluid delivery system 1100 is shown, Figure 12A The cartridge illuminated as green is shown, Figure 12B The cartridge illuminated as yellow is shown, and Figure 12C The cartridge illuminated as red is shown.

[0083] Figures 13A-13B An alternative embodiment of a pump assembly 1302 having a crankshaft 1312 is shown, with pistons 1320 attached to the crankshaft 1312 via connecting rods 1318. As Figure 13A shown, the connecting rods 1318 are eccentrically mounted to the shaft of the crankshaft 1312. Similar to the pump assembly described above with respect to Figure 10 the crankshaft 1312 can be driven by a variable speed motor that is mechanically coupled to the crankshaft 1312 via one or more gears. In this way, the motor can cause rotation of the crankshaft 1312 and control the speed of rotation of the crankshaft 1312.

[0084] Preferably, the crankshaft 1312 includes a single injection molded piece to reduce overall wear of the crankshaft 1312 over time. The crankshaft 1312 preferably includes a plurality of disks or pulleys 1316 disposed on the shaft of the crankshaft 1312, with adjacent pairs of disks or pulleys 1316 connected by a connecting rod 1314 disposed eccentrically on the shaft of the crankshaft 1312. One end of each connecting rod 1318 is connected to one of the connecting rods 1314.

[0085] As the crankshaft 1312 rotates, the disks or pulleys 1316 also rotate, which causes the connected pistons 1320 to move over time. It is contemplated that the pistons 1320 can be configured to contact the tubes 1332 of the cartridge 1330 as they move relative to the shaft of the crankshaft 1312, thereby causing fluid to flow within the tubes 1332, asFigure 13B The piston 1320 moves in a particular manner relative to the tube 1332, thereby forcing the fluid within the tube 1332 to flow. An increase in the rate of motion of the piston 1320 will similarly increase the flow rate of the fluid within the tube 1332. Likewise, a decrease in the rate of motion of the piston 1320 will similarly decrease the flow rate of the fluid within the tube 1332. Figure 10 The same considerations apply to the same parts having the same numbers appearing in Figures 13A-13B the remainder of the figures.

[0086] Figures 14A-14B An alternative embodiment of the pump unit 1402 of an infusion pump is shown having an eccentric cam 1412 that includes a plurality of discs or pulleys 1416 disposed on the shaft of the cam 1412 such that the center of the discs or pulleys 1416 is offset from the center of the shaft of the cam 1412. Similar to the pump unit described above with respect to Figure 10 the pump unit, the cam 1412 can be driven by a variable speed motor that is mechanically coupled to the cam 1412 via one or more gears. In this manner, the motor causes rotation of the cam 1412.

[0087] Preferably, the cam 1412 includes a single injection molded piece to reduce overall wear of the cam 1412 over time.

[0088] A plurality of intermediate pieces 1424 are disposed between the tube 1432 of the barrel 1430 and the discs or pulleys 1416 such that each intermediate piece 1424 is disposed adjacent to one of the discs or pulleys 1416 and the tube 1432. Each intermediate piece 1424 can be pivotally connected to a fixed piece 1426 by a link 1414. In this manner, as the cam 1412 rotates, each disc or pulley 1416 will press a different one of the intermediate pieces 1424 against the tube 1432, for example Figure 14A as shown in FIG. 14B, and then move away from the tube 1432, for example Figure 14B as shown in FIG. 14C. This generally sequential movement of the intermediate pieces 1424 against the tube 1432 results in the fluid flowing within the tube at a rate corresponding to the rotation of the cam 1412.

[0089] Figures 15A-15B A cross-sectional view of another embodiment of an infusion pump 1502 is shown that includes a housing 1504 that is configured to receive a replaceable and / or disposable barrel 1506 having a tube 1508. As described above, when the barrel 1506 is properly inserted into the infusion pump 1502, a portion of the tube 1508 of the barrel 1506 is disposed adjacent to a pump unit 1562. The tube 1508 can extend through the barrel 1506 to form, for example, a C-shape.

[0090] Infusion pump 1502 preferably includes a controller 1550 having a processor and a memory, wherein the memory is configured to store one or more control algorithms. Controller 1550 is configured to control motor 1560 of pump assembly 1562, thereby regulating the flow of fluid within tube 1508 of barrel 1506. In some embodiments, controller 1550 can be configured to also control locking mechanism 1540, such as one or more solenoids, to release barrel 1506. Locking mechanism 1540 can hold barrel 1506 within housing 1504 of infusion pump 1502 when locking mechanism 1540 is engaged with barrel 1506. Preferably, locking mechanism 1540 includes solenoids that pull in conjunction with notches or recessed areas of the left and right sides of barrel 1506 as described above. In some embodiments, barrel 1506 includes left and right notches to facilitate a user grasping barrel 1506.

[0091] Preferably, motor 1560 includes a variable speed motor mechanically coupled to crankshaft 1564 via a set of gears 1566. In this manner, motor 1560 causes rotation of crankshaft 1564 and controls the rotational speed of crankshaft 1564. Preferably, crankshaft 1564 includes a single injection molded piece to reduce overall wear of crankshaft 1564 over time. Crankshaft 1564 preferably includes a plurality of discs or pulleys 1568 disposed on the shaft of crankshaft 1564.

[0092] In some embodiments, at least some of discs or pulleys 1568 are disposed on the shaft such that at least some of discs or pulleys 1568 are offset from the center of the shaft of crankshaft 1564. It is contemplated that crankshaft 1564 can be modular and replaceable, such that pump assembly 1562 can be serviced for simple maintenance during the useful life of pump assembly 1562.

[0093] A set of pistons 1570 are each connected to crankshaft 1564 by a rod 1569. In preferred embodiments, rod 1569 is eccentrically mounted to the shaft of crankshaft 1564. In some embodiments, crankshaft 1564 discs or pulleys 1568 are disposed on the shaft of crankshaft 1564, adjacent pairs of discs or pulleys 1568 are connected by a link, wherein the link is disposed offset from the center of the shaft of crankshaft 1564. One end of each rod 1569 is connected to one of the links as described above.

[0094] As crankshaft 1564 rotates, discs or pulleys 1568 also rotate, which causes connected pistons 1570 to move over time (to Figure 15A the position of pistons 1570 in Figure 15BThe piston 1570 is expected to be configured to contact the tube 1508 of the barrel 1506 as the piston 1570 moves back and forth relative to the shaft of the crankshaft 1564, thereby causing fluid to flow within the tube 1508 of the barrel 1506. The piston 1570 moves in a particular manner relative to the tube 1508, thereby forcing the fluid within the tube 1508 to flow. An increase in the rate of movement of the piston 1570 will similarly increase the flow rate of the fluid within the tube 1508. Likewise, a decrease in the rate of movement of the piston 1570 will similarly decrease the flow rate of the fluid within the tube 1508.

[0095] Figures 16A-16G A cross-sectional view of another embodiment of an infusion pump 1602 is shown, which includes a housing 1604 configured to receive a replaceable and / or disposable barrel 1606 having a tube 1608. When the barrel 1606 is properly inserted into the infusion pump 1602, as shown, a portion of the tube 1608 of the barrel 1606 is disposed adjacent to a piston 1670 of a pump assembly 1662. The tube 1608 can extend through the barrel 1606 to form, for example, a C-shape. Figure 16B

[0096] The infusion pump can also include one or more latching mechanisms 1640, which can be used to secure and release the barrel 1606. For example, the latching mechanisms 1640 can hold the barrel 1606 within the housing 1604 of the infusion pump 1602 when engaged with the barrel 1606. Preferably, the latching mechanisms 1640 include solenoids that are pulled into engagement with notches or recessed areas on the left and right sides of the barrel 1606 as described above. In some embodiments, the barrel 1606 includes left and right notches to facilitate a user grasping the barrel 1606.

[0097] The infusion pump 1602 preferably includes a motor 1660 configured to control the pump assembly 1662 and thereby regulate the flow of fluid within the tube 1608 of the barrel 1606. In some embodiments, a controller (e.g., the controller shown in FIG. 16B) can be configured to control the speed of the motor 1660. Preferably, the motor 1660 includes a variable speed motor that is mechanically coupled to a crankshaft 1664 via a set of gears 1666. Figure 15A

[0098] Figure 16C A cross-sectional view of another embodiment of an infusion pump 1602 is shown, which includes a housing 1604 configured to receive a replaceable and / or disposable barrel 1606 having a tube 1608. When the barrel 1606 is properly inserted into the infusion pump 1602, as shown, a portion of the tube 1608 of the barrel 1606 is disposed adjacent to a piston 1670 of a pump assembly 1662. The tube 1608 can extend through the barrel 1606 to form, for example, a C-shape. Figure 16B ​​enlarged portion of the pump assembly 1662, showing how the pistons 1670 interact with the tubes 1608 of the cylinder 1606. As can be seen, the motor causes rotation of the gears 1666, which in turn causes rotation of the crankshaft 1664. As the crankshaft rotates, different ones of the pistons 1666 press against the tubes 1608, causing the tubes 1608 to be compressed, while other ones of the pistons 1666 move away from the tubes 1608, causing the tubes 1608 to fill with fluid. The sequential nature of the movement of the pistons 1670 causes fluid to move through the tubes 1608 in the direction shown in the figure. An increase in the rate of movement of the pistons 1670 will similarly increase the flow rate of the fluid within the tubes 1608. Likewise, a decrease in the rate of movement of the pistons 1670 will similarly decrease the flow rate of the fluid within the tubes 1608.

[0099] Figure 16D An exploded view of the pistons 1670 and the pull rods 1669 is shown in Figure 16E A partial assembly view of the pump assembly 1662 is shown. As shown, the pistons 1670 are connected to the discs or pulleys 1668 by the pull rods 1669, which have holes 1671 at one end configured to receive protrusions 1672 of the discs or pulleys 1668.

[0100] As Figure 16C shown, the crankshaft 1664 preferably includes a plurality of discs or pulleys 1668 disposed in series along the shaft of the crankshaft 1664. In a preferred embodiment, the pull rods 1669 are eccentrically mounted to the shaft of the crankshaft 1664. For example, the protrusions 1672 of each pulley 1668 can be disposed off-center from the center of the pulley 1668 and / or the pulleys 1668 can be ovoid or otherwise shaped. It is contemplated that the pulleys 1668 are sized and shaped and / or positioned so as to be disposable on the shaft of the crankshaft 1664 such that different ones of the pistons 1670 can press against the tubes 1608 at different times based on the relationship between the pistons 1670, the pulleys 1668, and the crankshaft 1664.

[0101] In a preferred embodiment, the cylinder 1606 includes a valve 1680 that can be used to inhibit the flow of fluid within the tubes 1608 of the cylinder 1606. Preferably, the valve 1680 is biased, for example, by the use of a spring 1681, in a closed position as shown in Figure 16A and Figure 16F which the spring 1681 causes the valve to compress a plug 1682 against the tubes 1608. The valve preferably includes the plug 1682 and a hook that wraps around at least a portion of the tubes 1608. As the plug 1682 and the hook come closer and closer together, the tubes 1608 are compressed, preventing fluid from flowing through the compressed portions of the tubes 1608, as shown in Figure 16F .

[0102] The actuator 1684 can be used to move the hook of the valve 1680 away from the stopper 1682, thus no longer compressing the tube 1608. Thus, as shown in Figure 16G FIG. 16, when force is applied to the actuator 1684, the tube 1608 is no longer compressed and fluid can flow through the tube 1608.

[0103] Preferably, the actuator 1684 is disposed on the outer surface of the barrel 1606 and extends outwardly away from the outer surface of the barrel 1606. Because the barrel 1606 is sized to be held in one hand, a medical professional can hold the barrel with one hand while using a finger of the hand holding the barrel to press the actuator 1684, thus priming the barrel 1606. As shown in Figure 16B FIG. 16, when the barrel 1606 is inserted into the housing 1604, the actuator 1684 can be depressed by the surface of the housing 1604 of the pump 1602 and held in that position.

[0104] The various embodiments described above can also include a spring or other mechanism located near the back of the barrel near the pump assembly that facilitates the ejection of the barrel from the infusion pump when the lockout mechanism is released. In addition to, or including, a spring, a push solenoid can be disposed within the housing and configured to contact the barrel and facilitate the ejection of the barrel from the hollow interior portion when the push solenoid is actuated.

[0105] As used herein, and unless the context clearly indicates otherwise, the term "connected to" is intended to include both direct connection (in which two elements that are connected to each other contact each other) and indirect connection (in which at least one additional element is located between the two elements). As such, the terms "connected to" and "connected with" are used synonymously.

[0106] In some embodiments, numbers that express quantities of components, such as concentrations, reaction conditions, and so forth, as used in describing and claiming certain embodiments of the present application, are to be understood as being modified in some instances by the term "about." Accordingly, in some embodiments, numerical parameters are approximations. Although the numerical ranges and parameters setting forth the broad scope of some embodiments of the application are approximations, the numerical values set forth in the specific examples are reported as precisely as practicable. The numerical values presented in some embodiments of the present application can contain certain errors necessarily resulting from the standard deviation found in their respective testing measurements.

[0107] All ranges recited herein are inclusive of the recited endpoints and open-ended ranges are inclusive of the excluded endpoints. Similarly, all lists recited herein are inclusive of all members individually and also inclusive of other non-specified members and ranges.

[0108] As used in the description of the application and the following claims, the meanings of "a", "an", and "the" include plural references unless the context clearly dictates otherwise. Additionally, as used in the description herein, "in" includes both "in" and "on" unless the context clearly dictates otherwise.

[0109] The recitation of numerical ranges by endpoints herein is merely intended to serve as a shorthand method of referring individually to each integer falling within the range. Unless otherwise indicated herein, each individual value is incorporated into the specification as if it were individually recited herein. All methods described herein can be performed in any suitable order unless otherwise indicated herein. The use of any and all examples, or exemplary language (e.g., "such as") provided herein, is intended merely to better illuminate the application and does not pose a limitation on the scope of the application otherwise claimed. No language in the specification should be construed as indicating any non-claimed element essential to the practice of the application.

[0110] Groupings of alternative elements or embodiments of the application disclosed herein are not to be construed as limitations. Each group member can be referred to and claimed individually or in any combination with other members of the group or other alternative elements or embodiments found herein. One or more groups of alternative members or embodiments of any of the groups described herein can be included in, or deleted from, such description, and each reference to a group or potentially alternative embodiment is intended to include a like reference to each and every sub-group, permutation, and combination of sub-groups included in the described group or alternative embodiment. Such descriptions, although discrete, need not be mutually exclusive. Aspects of the application can be implemented in any of the combinations or sub-combinations of the aspects specified herein.

[0111] It will be obvious to a person skilled in the art that, in addition to the modifications already described, many modifications can be made to the application as described herein without, however, departing from the inventive concept thereof. Consequently, the subject matter of the application is not limited to the spirit of the attached claims only, but is otherwise not restricted. Furthermore, all terms are to be interpreted in the broadest possible way in accordance with the context in which they are used in the specification and claims. In particular, the terms "comprising", "comprise" and "comprised of" should be interpreted as referring to elements, components or steps in a non-exclusive manner, indicating that there can be additional elements, components or steps not specifically mentioned, or that there can be combinations of elements, components or steps in addition to those specifically mentioned. Where the specification and claims refer to at least one of something selected from the group consisting of A, B, C.... and N, this is to be interpreted into a specific group of at least one of the listed elements, that is, A, B, C,.... and / or N, but not A plus B, or B plus N, etc.

Claims

1. A fluid delivery system, comprising: an infusion pump having a housing with a first opening and a hollow interior portion configured to receive a cartridge having a tube; a pump assembly disposed within the housing and comprising: a motor mechanically coupled to a crankshaft having a shaft, the crankshaft further comprising a set of pulleys disposed on or coupled to the crankshaft; and, wherein each pulley has a protrusion extending from a first edge in a direction parallel to the crankshaft; wherein the center of the protrusion is offset from the shaft; a set of levers, wherein each lever is connected to one of the pulleys via the protrusion such that the lever is movable relative to the pulley; a set of pistons, and wherein each of the pistons is connected to the crankshaft via one of the levers such that the lever is movable relative to the piston, wherein each of the pistons is connected to one of the pulleys via one of the levers, and each lever connects one of the pulleys such that the lever is movable relative to the pulley; and wherein the pistons are configured to move over time as the crankshaft rotates, and when the cartridge is disposed in the hollow interior portion, the pistons are configured to compress different portions of the tube of the cartridge over time as the crankshaft rotates, thereby causing movement of the pulleys, levers, and pistons.

2. The fluid delivery system of claim 1, wherein, the crankshaft and pulleys comprise a single injection molded piece.

3. The fluid delivery system of claim 1, wherein, further comprising: a controller having a processor and a memory and configured to receive information and send command signals; and wherein the controller is communicatively coupled to the pump assembly and wherein the pump assembly is configured to receive the command signals to thereby control the speed of the motor. further comprising:

4. The fluid delivery system of claim 3, wherein, at least one latching solenoid disposed within the housing; wherein the cartridge comprises at least one recess; and wherein the at least one latching solenoid comprises a protrusion configured to be received within the recess of the cartridge to thereby secure the cartridge in the hollow interior portion of the housing; and wherein the controller is further configured to control the at least one latching solenoid; a set of manual actuators, each of which when manually actuated thereby causes one of the at least one latching solenoids to release the cartridge. the controller is disposed within the housing of the infusion pump.

5. The fluid delivery system of claim 3, wherein, the controller is disposed outside of the housing of the infusion pump in a separate device.

6. The fluid delivery system of claim 3, wherein, further comprising:

7. The fluid delivery system of claim 6, wherein, a second infusion pump having a second housing with a second opening and a second hollow interior portion configured to receive a second cartridge having a second tube; a second pump assembly disposed within the housing and comprising a second motor mechanically coupled to a second crankshaft having a second set of pulleys disposed on or coupled to the second crankshaft; and wherein the second pump assembly further comprises a second set of pistons and a second set of levers, and wherein each of the second set of pistons is connected to the second crankshaft via each of the second set of levers, wherein each of the second set of levers is connected to each of the second set of pulleys; wherein the second set of pistons are configured to move over time as the second crankshaft rotates, and when the second cartridge is disposed in the second hollow interior portion, the second set of pistons are configured to compress different portions of the second tube of the second cartridge over time as the second crankshaft rotates, thereby causing movement of the second set of pulleys, second set of levers, and second set of pistons. wherein the second set of pistons is configured to compress different portions of the second tubing of the second barrel over time as the second crank rotates when the second barrel is disposed within the second hollow interior portion; and wherein the controller is communicatively coupled to the second pump assembly and wherein the second pump assembly is configured to receive the command signal.

8. The fluid delivery system of claim 1, wherein, Also included is: at least one light source disposed within the housing and configured to illuminate the hollow interior and the barrel.

9. The fluid delivery system of claim 1, wherein, Also included is: a display separate from and in communication with the infusion pump, wherein the display can receive information from the infusion pump and send commands to the infusion pump to control the pump assembly.

10. The fluid delivery system of claim 9, wherein, The housing includes a slot configured to movably house a portion of the display.

11. The fluid delivery system of claim 1, wherein, Also included is a sensor configured to monitor a flow rate of a fluid within the tubing.

12. The fluid delivery system of claim 1, wherein, Also included is a sensor configured to measure a characteristic of a fluid within the tubing.

13. A barrel for a fluid delivery system, comprising: a housing having a top and a bottom, and a first side extending between the top and the bottom, wherein the housing is configured to hold a portion of tubing through which a medication can flow from a source of the medication to a patient, and wherein the tubing enters the barrel from the top, extends through the barrel along the top, the first side, and the bottom to form a C-shape, and exits the barrel at the bottom; a valve configured to compress the tubing and prevent fluid flow in the tubing when the valve is in a first position; and an actuator mechanically coupled to the valve, whereby when a force is applied to the actuator, the valve moves to a second position that allows fluid to flow through the tubing; and wherein the valve is biased in the first position.

14. The cartridge of claim 13, wherein, The valve includes a hook and a plug, wherein the plug is disposed between the actuator and the hook, and wherein the tubing is disposed between the plug and the hook, such that the hook extends around a portion of the tubing, and wherein the hook is configured to push the tubing toward the plug, and thereby compress the tubing against the plug and prevent fluid flow in the plug when the valve is in the first position.

15. The cartridge of claim 13, wherein, The housing includes a tapered top surface and a tapered bottom surface.

16. The cartridge of claim 13, wherein, A portion of the tubing that extends generally horizontally through the barrel from the first side to the bottom can be disposed at an angle greater than zero degrees from a horizontal surface.

17. The cartridge of claim 13, wherein, The actuator is disposed on and extends outwardly from a top surface of the housing.

18. A fluid delivery system, comprising: a barrel, comprising: a barrel housing having a top and a bottom, and a first side extending between the top and the bottom, wherein the barrel housing is configured to hold a portion of tubing through which a medication can flow from a source of the medication to a patient, and wherein the tubing enters the barrel from the top, extends through the barrel along the top, the first side, and the bottom to form a C-shape, and exits the barrel at the bottom; a valve configured to compress the tubing and prevent fluid flow in the tubing when the valve is in a first position; and a sensor configured to monitor a flow rate of a fluid within the tubing. an actuator mechanically connected to the valve, whereby when the actuator is pressed, the valve moves to a second position allowing fluid to flow through the tube; and wherein the valve is biased in the first position; an infusion pump having a housing with a first opening and a hollow interior portion configured to receive the cartridge; a pump assembly disposed within the housing and including a motor mechanically connected to a crankshaft having a shaft, the crankshaft having a set of pulleys disposed on or connected to the crankshaft; and, wherein each pulley has a protrusion extending from a first edge in a direction parallel to the crankshaft; wherein the center of the protrusion is offset from the shaft; wherein the pump assembly further includes a set of pistons and a set of pull rods, and wherein each pull rod is connected to one of the pulleys via the protrusion such that the pull rod is movable relative to the pulley, and wherein each piston is connected to one of the pull rods such that the pull rod is movable relative to the piston, wherein each piston is connected to one of the pulleys via one of the pull rods; and wherein, when the cartridge is disposed in the hollow interior portion, the pistons are configured to compress different portions of the tube of the cartridge over time as the crankshaft rotates, thereby causing movement of the pulleys, pull rods, and pistons.

19. The fluid delivery system of claim 18, wherein, further comprising: a controller having a processor and a memory and configured to receive information and send command signals; and wherein the controller is communicatively coupled to the pump assembly and wherein the pump assembly is configured to receive the command signals to control the speed of the motor.

20. The fluid delivery system of claim 19, wherein, the controller is disposed within the infusion pump or in a control unit separate from the housing.

21. The fluid delivery system of claim 18, wherein, A portion of the tube of the cartridge extending generally horizontally from the first edge to the bottom can be disposed at an angle greater than zero degrees from a horizontal surface.

22. The fluid delivery system of claim 18, wherein, The valve includes a hook and a plug, and wherein the tube is disposed between the plug and the hook, and wherein the hook is configured to press the tube against the plug when the valve is in the first position, preventing fluid flow in the tube.

23. The fluid delivery system of claim 19, wherein, further comprising: at least one latching solenoid disposed within the housing; wherein the cartridge includes at least one recess; and wherein the at least one latching solenoid includes a protrusion configured to be received within the recess of the cartridge, thereby securing the cartridge in the hollow interior portion of the housing; and wherein the controller is further configured to control the at least one latching solenoid; and a set of manual actuators, each of which when manually actuated thereby causes one of the at least one latching solenoids to release the cartridge.

24. The fluid delivery system of claim 18, wherein, further comprising: at least one light source disposed within the housing and configured to illuminate the hollow interior and the cartridge; wherein the at least one light source is configured to emit light based on a state of the infusion pump; and wherein the cartridge housing is translucent.

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