Sample centrifugation mechanism and sample analyzer

Abstract

The present invention discloses a sample centrifugation mechanism and a sample analyzer. The sample centrifugation mechanism includes a bracket, a tray, and components such as an inlet / outlet and a centrifugal pressing component. The bracket is provided with a first position and a second position. The tray component includes a movable seat that bears a tray piece and is slidably connected to the bracket. The inlet / outlet bin component includes an inlet / outlet driving member that drives the movable seat to move between the first position and the second position. The centrifugal pressing component provided at the second position includes a movable pressing head and a pressing seat that are rotatably connected, a pressing driving member, a fixed pressing head and a centrifugal driving member that are connected. The movable pressing head and the fixed pressing head are arranged corresponding to each other, and at least one of them is a magnetic part and they attract each other. The pressing seat is movably connected to the bracket. When the movable seat is at the second position, the pressing driving member drives the pressing seat to drive the movable pressing head to approach the fixed pressing head along the bracket and press the disc, and the centrifugal driving member drives the fixed pressing head to rotate the disc. The sample centrifugation mechanism of the present invention will not generate large vibrations and noises.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and particularly to a sample centrifugation mechanism and a sample analyzer. Background Art

[0002] Currently, for the analysis of whole blood samples, it is usually necessary to place the whole blood samples into a disc and centrifuge to obtain plasma, and then put the plasma into a sample analyzer. Before centrifuging the disc, the centrifuge needs to press the disc tightly. If the disc cannot be pressed tightly, the disc is likely to deviate, resulting in incomplete centrifugation of the samples in the disc. Existing centrifuges usually increase the contact area with the disc to make the disc pressed tightly, but this will increase the centrifugation mass, resulting in large vibrations and noises when the existing centrifuge centrifuges the samples.

[0003] In view of the above defects, it is necessary to provide a new sample centrifugation mechanism and a sample analyzer. Summary of the Invention

[0004] The main object of the present invention is to provide a sample centrifugation mechanism and a sample analyzer, aiming to solve the problems of large vibrations and noises generated when the existing centrifuge centrifuges the samples.

[0005] To achieve the above object, the sample centrifugation mechanism proposed by the present invention includes:

[0006] A bracket, which is provided with a first position and a second position at intervals;

[0007] A tray assembly, including a movable seat for supporting the disc, and the movable seat is slidably connected to the bracket;

[0008] An inlet / outlet bin assembly, including an inlet / outlet driving member, and the inlet / outlet driving member is used to drive the movable seat to move between the first position and the second position;

[0009] A centrifugal pressing assembly, which is arranged at the second position and includes a movable pressing head, a pressing seat, a pressing driving member, a fixed pressing head and a centrifugal driving member. The movable pressing head and the pressing seat are rotatably connected. The fixed pressing head is connected to the centrifugal driving member. The movable pressing head and the fixed pressing head are arranged corresponding to each other. At least one of the movable pressing head and the fixed pressing head is a magnetic part and they attract each other. The pressing seat is movably connected to the bracket;

[0010] When the movable seat is located at the second position, the pressing driving member is used to drive the pressing seat to move relative to the bracket, so as to drive the movable pressing head to approach the fixed pressing head and press the disc tightly, and the centrifugal driving member is used to drive the fixed pressing head to rotate the disc.

[0011] Preferably, the disc is provided with a through hole. The fixed pressure head and the movable pressure head are both abutted against the through hole and have a gap therebetween to press the disc tightly. The movable seat is provided with an avoidance groove, and the tray is provided with an avoidance hole. Both the avoidance groove and the avoidance hole are used to avoid the fixed pressure head.

[0012] Preferably, the fixed pressure head includes a pressure head bracket and a pressing magnet. The pressure head bracket is provided with a mounting hole, and the pressing magnet is embedded in the mounting hole. The movable pressure head is a magnetic pressure head attracted to the pressing magnet. The pressing seat is provided with a mounting plate. The movable pressure head is rotatably arranged on the mounting plate, and a protruding shaft is arranged on one side of the movable pressure head corresponding to the fixed pressure head. The protruding shaft is used to insert into the mounting hole. The pressing magnet and the protruding shaft are both abutted against the through hole and have a gap therebetween to press the disc tightly. When the disc is pressed tightly, the pressing driving member is further used to drive the pressing seat to move relative to the bracket, so that there is a gap between the mounting plate and the movable pressure head in the up and down direction.

[0013] Preferably, the bracket is provided with a slide rail extending in the vertical direction, and the pressing seat is provided with a chute slidably connected to the slide rail.

[0014] Preferably, the pressing driving member and the feeding and discharging driving member are shared. An upward elastic member is connected between the pressing seat and the bracket. When the movable seat is in the second position, the movable seat is clamped with the pressing seat. The feeding and discharging driving member is further used to drive the movable seat to drive the pressing seat to move relative to the bracket, so as to drive the movable pressure head to approach the fixed pressure head and press the disc tightly. The centrifugal driving member is used to drive the fixed pressure head to rotate the disc.

[0015] Preferably, the bracket is provided with a trajectory guiding plate slidably connected to the movable seat. The feeding and discharging bin assembly further includes a swing fork movably connected to the bracket and the movable seat respectively. The feeding and discharging driving member is used to drive the swing fork to drive the movable seat to move between the first position and the second position. When the movable seat is in the second position, the feeding and discharging driving member is further used to drive the movable seat to drive the pressing seat to move relative to the bracket through the swing fork, so as to drive the movable pressure head to approach the fixed pressure head and press the disc tightly.

[0016] Preferably, the trajectory guiding plate has a trajectory groove. A guiding groove is provided on the movable seat, and a tracking pin inserted into the guiding groove is also inserted into the trajectory groove and slidably connected to the groove wall of the trajectory groove, and is movably connected to the end of the swing fork away from the bracket. The in-out driving member is used to drive the swing fork to move along the trajectory groove. A clutch card slot is provided on the pressing seat. When the movable seat is in the second position, the tracking pin is snapped into the clutch card slot.

[0017] Preferably, the trajectory groove includes a horizontally connected horizontal trajectory groove and a vertical trajectory groove. The in-out driving member is used to drive the swing fork to drive the movable seat to move between the first position and the second position along the horizontal trajectory groove. The in-out driving member is used to drive the swing fork to drive the movable pressing head to approach the fixed pressing head to press the disc along the vertical trajectory groove through the pressing seat.

[0018] Preferably, round holes and waist-shaped holes are respectively formed at both ends of the swing fork. The tracking pin is inserted into the round hole. A fixed pin is provided on the bracket, and a power pin is provided on the in-out driving member. Both the fixed pin and the power pin are inserted into the waist-shaped hole.

[0019] In addition, the present invention also provides a sample analyzer, which includes a housing and the sample centrifugation mechanism as described above accommodated in the housing.

[0020] The sample centrifugation mechanism of the present invention includes a bracket, a tray assembly, an inlet / outlet bin assembly, and a centrifugal pressing assembly. The bracket is provided with a first position and a second position at intervals. The tray assembly includes a movable seat for supporting a disk, and the movable seat is slidably connected to the bracket. The inlet / outlet bin assembly includes an inlet / outlet driving member for driving the movable seat to move between the first position and the second position. The centrifugal pressing assembly is disposed at the second position and includes a movable pressing head, a pressing seat, a pressing driving member, a fixed pressing head, and a centrifugal driving member. The movable pressing head and the pressing seat are rotatably connected, the fixed pressing head is connected to the centrifugal driving member, the movable pressing head and the fixed pressing head are arranged corresponding to each other, and at least one of the movable pressing head and the fixed pressing head is a magnetic member and they attract each other. The pressing seat is movably connected to the bracket. When centrifuging the sample in the disk, the inlet / outlet driving member drives the movable seat to reach the first position, places the disk containing the sample on the movable seat, the inlet / outlet driving member drives the movable seat to move from the first position to the second position. After the movable seat is in the second position, the pressing driving member drives the pressing seat to move relative to the bracket to drive the movable pressing head to approach the fixed pressing head and press the disk. After the disk is pressed, the centrifugal driving member drives the fixed pressing head to rotate the disk. When the centrifugation ends, the pressing driving member drives the pressing seat to move relative to the bracket to drive the movable pressing head to move away from the fixed pressing head and loosen the disk, and the inlet / outlet driving member drives the movable seat to move from the second position to the first position. In the present invention, at least one of the movable pressing head and the fixed pressing head for pressing the disk is set as a magnetic member, and the two attract each other, so that the disk can be pressed during centrifugation, rather than by increasing the contact area between the movable pressing head and the fixed pressing head and the disk, so that the masses of the fixed pressing head and the movable pressing head moving with the disk during centrifugation are small, thereby reducing the overall centrifugal mass, and enabling the sample centrifugation mechanism to not generate large vibrations and noises when centrifuging the sample on the disk. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the following drawings are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on the structures shown in these drawings.

[0022] Figure 1 It is a schematic structural view of a perspective of the movable seat in the first position in an embodiment of the present invention;

[0023] Figure 2 It is a schematic structural view of another perspective of the movable seat in the first position in an embodiment of the present invention;

[0024] Figure 3 It is a schematic structural view of still another perspective of the movable seat in the first position in an embodiment of the present invention;

[0025] Figure 4 Schematic cross-sectional view of the movable seat in the first position in an embodiment of the present invention;

[0026] Figure 5 Exploded view of the movable seat in the first position in an embodiment of the present invention;

[0027] Figure 6 Schematic structural view of a perspective of the movable seat in the second position and the disc being in the loose state in an embodiment of the present invention;

[0028] Figure 7 Schematic structural view of another perspective of the movable seat in the second position and the disc being in the loose state in an embodiment of the present invention;

[0029] Figure 8 Schematic structural view of yet another perspective of the movable seat in the second position and the disc being in the loose state in an embodiment of the present invention;

[0030] Figure 9 Schematic cross-sectional view of the movable seat in the second position and the disc being in the loose state in an embodiment of the present invention;

[0031] Figure 10 Schematic structural view of a perspective of the movable seat in the second position and the disc being in the pressed state in an embodiment of the present invention;

[0032] Figure 11 Schematic structural view of another perspective of the movable seat in the second position and the disc being in the pressed state in an embodiment of the present invention;

[0033] Figure 12 Schematic structural view of yet another perspective of the movable seat in the second position and the disc being in the pressed state in an embodiment of the present invention;

[0034] Figure 13 Schematic cross-sectional view of the movable seat in the second position and the disc being in the pressed state in an embodiment of the present invention.

[0035] Explanation of the reference numerals in the drawings:

[0036] Label Name Label Name 1 Bracket 2221 Clamping portion 11 First position 223 Blocking wall 12 Second position 2231 Receiving space 13 Fixed pin 3 In-and-out bin assembly 14 Second connecting piece 31 In-and-out driving piece 15 Slide rail 311 Power pin 16 Track guiding plate 32 Swing fork 161 Track groove 33 Transmission piece 1611 Horizontal track groove 331 Lead screw 1612 Vertical track groove 332 Lead screw nut seat 2 Tray assembly 4 Centrifugal pressing assembly 21 Movable seat 41 Movable pressing head 211 Tracking pin 42 Pressing seat 212 Guiding seat 421 Pull-down card slot 213 First connecting piece 422 Chute 2131 First sub-guide rail 423 Clutch card slot 2132 Second sub-guide rail 43 Fixed pressing head 214 Guiding slot 44 Centrifugal driving piece 22 Tray 45 Upward elastic piece 221 Lifting elastic piece 10 Disc 222 Pull rod

[0037] The realization, functional features and advantages of the object of the present invention will be further described with reference to the embodiments and the accompanying drawings. Detailed implementation manners

[0038] The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0039] It should be noted that all directional indications (such as up, down, left, right, front, back...) in the embodiments of the present invention are only used to explain the relative position relationship, movement conditions, etc. between components in a specific posture (as shown in the drawings). If the specific posture changes, the directional indications will also change accordingly.

[0040] In addition, the descriptions such as "first" and "second" in the present invention are only for descriptive purposes, and cannot be understood as indicating or implying their relative importance or implicitly indicating the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include at least one of such features. In the description of the present invention, "a plurality of" means at least two, such as two, three, etc., unless otherwise specifically defined.

[0041] In the present invention, unless otherwise clearly defined and limited, the terms "connected", "fixed", etc. shall be understood in a broad sense. For example, "fixed" may be a fixed connection, a detachable connection, or integrated; it may be a mechanical connection or an electrical connection; it may be directly connected or indirectly connected through an intermediate medium, and it may be the internal communication of two components or the interaction relationship between two components, unless otherwise clearly limited. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific situations.

[0042] In addition, the technical solutions between the various embodiments of the present invention can be combined with each other, but it must be based on the ability of those of ordinary skill in the art to implement. When the combination of technical solutions is contradictory or cannot be implemented, it should be considered that such a combination of technical solutions does not exist and is not within the protection scope required by the present invention.

[0043] The present invention provides a sample centrifugation mechanism and a sample analyzer, aiming to solve the problems that the existing centrifuges will generate relatively large vibration and noise when centrifuging samples.

[0044] Please refer to Figures 1 to 5As shown, the sample centrifugation mechanism includes a bracket 1, a tray assembly 2, a loading and unloading assembly 3, and a centrifugal pressing assembly 4. The bracket 1 is provided with a first position 11 and a second position 12 at intervals. The tray assembly 2 includes a movable seat 21 for supporting the wafer 10. The movable seat 21 is slidably connected to the bracket 1. The loading and unloading assembly 3 includes a loading and unloading driving member 31, which is used to drive the movable seat 21 to move between the first position 11 and the second position 12. The centrifugal pressing assembly 4 is arranged at the second position 12 and includes a movable pressing head 41, a pressing seat 42, a pressing driving member, a fixed pressing head 43, and a centrifugal driving member 44. The movable pressing head 41 is rotatably connected to the pressing seat 42. The fixed pressing head 43 is connected to the centrifugal driving member 44. The movable pressing head 41 is arranged corresponding to the fixed pressing head 43. At least one of the movable pressing head 41 and the fixed pressing head 43 is a magnetic part and they attract each other. The pressing seat 42 is movably connected to the bracket 1. When the movable seat 21 is located at the second position 12, the pressing driving member is used to drive the pressing seat 42 to move relative to the bracket 1, so as to drive the movable pressing head 41 to approach the fixed pressing head 43 and press the wafer 10. The centrifugal driving member 44 is used to drive the fixed pressing head 43 to rotate the wafer 10.

[0045] The sample centrifuge mechanism of the present invention includes a bracket 1, a tray assembly 2, an in-and-out bin assembly 3 and a centrifugal pressing assembly 4. The bracket 1 is provided with a first position 11 and a second position 12 at intervals. The tray assembly 2 includes a movable seat 21 for supporting a tray sheet 10, and the movable seat 21 is slidably connected to the bracket 1. The in-and-out bin assembly 3 includes an in-and-out driving member 31, and the in-and-out driving member 31 is used to drive the movable seat 21 to move between the first position 11 and the second position 12. The centrifugal pressing assembly 4 is arranged at the second position 12, and includes a movable pressure head 41, a pressing seat 42, a pressing driving member, a fixed pressure head 43 and a centrifugal driving member 44. The movable pressure head 41 is rotatably connected to the pressing seat 42, the fixed pressure head 43 is connected to the centrifugal driving member 44, the movable pressure head 41 and the fixed pressure head 43 are correspondingly arranged, at least one of the movable pressure head 41 and the fixed pressure head 43 is a magnetic suction member and attracts each other, and the pressing seat 42 is movably connected to the bracket 1. When the movable seat 21 is in the second position 12, the clamping drive member is used to drive the clamping seat 42 to move relative to the bracket 1, so as to drive the movable pressure head 41 to approach the fixed pressure head 43 and clamp the disc 10, and the centrifugal drive member 44 is used to drive the fixed pressure head 43 to rotate the disc 10. When the sample in the disc 10 needs to be centrifuged, the in-out drive member 31 drives the movable seat 21 to reach the first position 11, and the disc 10 containing the sample is placed on the movable seat 21. The in-out drive member 31 drives the movable seat 21 to move from the first position 11 to the second position 12. After the movable seat 21 is in the second position 12, the clamping drive member drives the clamping seat 42 to move relative to the bracket 1, so as to drive the movable pressure head 41 to approach the fixed pressure head 43 and clamp the disc 10. The clamping seat 42 will move upward a small distance and disengage from the movable pressure head 41. The disc 10 is separated from the contact and then centrifuged again, so that the disc 10 can be continuously clamped between the fixed pressure head 43 and the movable pressure head 41 by magnetic force, and the movable pressure head 41, the disc 10 and the fixed pressure head 43 are centrifugally rotated together, and the centrifugal driving member 44 drives the fixed pressure head 43 to rotate the disc 10. When the centrifugation is completed, the clamping driving member drives the clamping seat 42 to move relative to the bracket 1 to drive the movable pressure head 41 away from the fixed pressure head 43 and release the disc 10, and the in-out driving member 31 drives the movable seat 21 to move from the second position 12 to the first position 11. The present invention provides a method of compressing the disk 10 by configuring at least one of the movable pressure head 41 and the fixed pressure head 43 as a magnetic attraction member, and the two attract each other, so that the disk 10 can be compressed during centrifugation, rather than increasing the contact area between the movable pressure head 41 and the fixed pressure head 43 and the disk 10, thereby reducing the mass of the fixed pressure head 43 and the movable pressure head 41 that move with the disk 10 during centrifugal motion, thereby reducing the overall centrifugal mass, so that the sample centrifuge mechanism will not generate large vibrations and noises when centrifuging the sample on the disk 10.

[0046] Please combine Figure 2 and Figure 7As shown, an in-and-out bin home position optocoupler baffle is provided on the movable seat 21, and an in-and-out bin home position optocoupler is provided on the bracket 1. The in-and-out bin home position optocoupler baffle can move horizontally in and out together with the tray assembly 2. The in-and-out bin home position optocoupler baffle and the in-and-out bin home position optocoupler cooperate to determine the horizontal home position of the movable seat 21 and the disc 10, and this position is directly above the centrifugal motor.

[0047] Please refer to Figure 6 and Figure 10 As shown, a pressing home position optocoupler baffle is provided on the pressing seat 42, and a pressing assembly home position optocoupler is provided on the bracket 1. When the pressing assembly moves upward and returns to the home position, the pressing home position optocoupler baffle blocks the pressing assembly home position optocoupler.

[0048] A circumferential home position optocoupler groove is provided on the disc 10, and a circumferential home position optocoupler of the disc 10 is provided on the bracket 1. The circumferential home position optocoupler groove and the circumferential home position optocoupler of the disc 10 act together to determine the circumferential position of the disc 10, thus avoiding the trouble of manual circumferential positioning or manually locking the disc 10 when the reaction disc is placed; this groove can be a hollow near-sector hole or a sector light-transmitting hole on an opaque film. The circumferential home position optocoupler of the disc 10 can be a reflective type, a transmissive type, a Hall element, etc. When using a transmissive optocoupler, the emitting end and the receiving end face of the optocoupler are respectively located on the upper and lower surfaces of the disc 10, and there should be a light-transmitting or light-blocking hole in the area corresponding to the optocoupler light path on the disc 10; in addition, the disc 10 and the circumferential reflective home position optocoupler can be changed to a U-shaped groove type opposed optocoupler, and the emitting and receiving end faces of the optocoupler are located outside the upper and lower surfaces of the disc 10, and there should be a light-transmitting or light-blocking hole in the area corresponding to the optocoupler light path on the disc 10.

[0049] It should be noted that the centrifugal disc 10 in the present invention contains a cavity, a pressing and positioning hole, a sample adding and sampling hole, and a circumferential home position hole, and can hold the plasma sample to be measured separated after centrifuging the whole blood sample. The centrifugal disc 10 is provided with an inner ring hole and an outer ring hole. The inner ring hole is the hole for adding the whole blood sample into the centrifugal disc, and the outer ring hole is the hole for sucking out the centrifuged plasma sample from the disc 10.

[0050] In one embodiment, the disk 10 is provided with through holes. The fixed pressure head 43 and the movable pressure head 41 are in contact with each other at the through holes and there is a gap therebetween to press the disk 10 tightly. The movable seat 21 is provided with an avoidance groove, and the tray 22 is provided with an avoidance hole. Both the avoidance groove and the avoidance hole are used to avoid the fixed pressure head 43. To ensure that the disk 10 can be stable and reliable during centrifugal motion, the disk 10 is provided with through holes, and the fixed pressure head 43 and the movable pressure head 41 are in contact with each other at the through holes to press the disk 10 tightly. Moreover, the movable seat 21 is provided with an avoidance groove, and the tray 22 is provided with an avoidance hole. When the movable seat 21 enters the second position 12 from the first position 11, the avoidance groove can avoid the fixed pressure head 43. When the tray 22 is pulled down, the avoidance hole on the tray 22 can avoid the fixed pressure head 43, so as to ensure that the fixed pressure head 43 can be inserted into the through hole. It should be noted that the lower surface of the movable pressure head 41 and the upper surface of the fixed pressure head 43 never come into contact with each other, so that a gap can be maintained between the movable pressure head 41 and the fixed pressure head 43, and then the movable pressure head 41 can press the disk 10 tightly against the fixed pressure head 43.

[0051] Further, the fixed indenter 43 includes an indenter bracket 1 and a pressing magnet. The indenter bracket 1 is provided with a mounting hole, and the pressing magnet is embedded in the mounting hole. The movable indenter 41 is a magnetic indenter attracted to the pressing magnet. The pressing seat 42 is provided with a mounting plate, and the movable indenter 41 is rotatably arranged on the mounting plate. A protruding shaft is provided on one side of the movable indenter 41 corresponding to the fixed indenter 43. The protruding shaft is used to insert into the mounting hole. The pressing magnet and the protruding shaft are in contact and have a gap at the through hole to press the disc 10. When the disc 10 is pressed, the pressing driving member is further used to drive the pressing seat 42 to move relative to the bracket 1, so that there is a gap between the mounting plate and the movable indenter 41 in the vertical direction. When the fixed indenter 43 and the movable indenter 41 approach, the fixed indenter 43 and the movable indenter 41 generate a suction force in the up and down axial directions to press the disc 10 to be centrifuged together. The longitudinal section of the movable indenter 41 is in an I shape, and the groove width of the I shape of the movable indenter 41 is slightly larger than the thickness of the mounting plate on the pressing seat 42 for mounting the movable indenter 41. After pressing the disc 10, the mounting plate moves slightly upward, the movable indenter 41 is separated from contact with the mounting plate, and rotates at a high speed together with the disc 10 during centrifugation. Moreover, the protruding shaft of the movable indenter 41 is slightly smaller than the mounting hole. In one embodiment, the protruding shaft is in an inverted frustum structure, and the bottom diameter of the protruding shaft is smaller than the mounting hole, which is convenient for the protruding shaft to insert into the mounting hole. The size of the top of the protruding shaft is larger than the mounting hole, so that the outer peripheral wall of the protruding shaft can abut against the upper edge of the mounting hole, which can not only press the disc 10, but also enable the disc 10 to automatically align in the plane to ensure the coaxiality of the disc 10. Among them, the mounting plate restricts the micro-movement of the movable indenter 41 relative to it in the horizontal plane and the vertical direction; the pressing magnet provides the attractive force required for pressing the disc 10 when the disc 10 is centrifuged; the indenter bracket 1 provides axial and circumferential positioning for the disc 10 when the disc 10 is centrifuged, and is also the mounting seat of the pressing magnet. It should be noted that the height of the magnet of the fixed indenter 43 is less than the depth of the mounting hole, which can also protect the magnet and prevent the magnet from being squeezed and impacted.

[0052] Further, a slide rail 15 extending in the vertical direction is provided on the bracket 1, and a sliding groove 422 slidably connected to the slide rail 15 is provided on the pressing seat 42. In one embodiment, a front slider and a rear slider both having the sliding groove 422 are provided on the pressing seat 42. The front slider is arranged on the front side of the pressing seat 42, and the rear slider is arranged on the rear side of the pressing seat 42. A front slide rail 15 and a rear slide rail 15 are provided on the bracket 1. The front slider is slidably connected to the front slide rail 15 correspondingly, and the rear slider is slidably connected to the rear slide rail 15 correspondingly, so that the pressing seat 42 can slide stably and reliably along the bracket 1 in the vertical direction.

[0053] Further, the pressing driving member is shared with the inlet / outlet driving member 31. An upward elastic member 45 is connected between the pressing seat 42 and the bracket 1. When the movable seat 21 is located at the second position 12, the movable seat 21 is clamped with the pressing seat 42. The inlet / outlet driving member 31 is further configured to drive the movable seat 21 to drive the pressing seat 42 to move relative to the bracket 1, so as to drive the movable pressing head 41 to approach the fixed pressing head 43 and press the disc 10. The centrifugal driving member 44 is configured to drive the fixed pressing head 43 to rotate the disc 10. In an embodiment, the bracket 1 is provided with a track guiding plate 16, and the first position 11 and the second position 12 are spaced on the bracket 1. The tray assembly 2 includes a movable seat 21 which is slidably connected to the track guiding plate 16 and the bracket 1 respectively. The inlet / outlet assembly 3 includes an inlet / outlet driving member 31. The centrifugal pressing assembly 4 is disposed at the second position 12 and includes a movable pressing head 41 and a pressing seat 42 which are rotatably connected, and a fixed pressing head 43 and a centrifugal driving member 44 which are connected. The movable pressing head 41 and the fixed pressing head 43 are correspondingly arranged. The pressing seat 42 is movably connected to the bracket 1 and an upward elastic member 45 is connected therebetween. Please refer to Figures 1 to 4 As shown, when centrifugal motion needs to be performed on the sample in the disc 10, the inlet / outlet driving member 31 drives the movable seat 21 to reach the first position 11, places the disc 10 containing the sample on the movable seat 21, and the inlet / outlet driving member 31 drives the movable seat 21 to move from the first position 11 to the second position 12. Please refer to Figures 6 to 9 and Figure 13 As shown, at this time, the movable seat 21 is clamped with the pressing seat 42 at the second position 12. The inlet / outlet driving member 31 drives the movable seat 21 to move along the track guiding plate 16 again, and drives the movable pressing head 41 on the pressing seat 42 to approach the fixed pressing head 43 to press the disc 10. Please refer to Figures 10 to 13 As shown, at this time, the upward elastic member 45 is deformed. After the disc 10 is pressed, the centrifugal driving member 44 drives the fixed pressing head 43 to rotate the disc 10. When the centrifugation ends, the inlet / outlet driving member 31 drives the movable seat 21 to move from the second position 12 to the first position 11 along the track guiding plate 16. It should be noted that when the centrifugation ends, the movable seat 21 is separated from the pressing seat 42, the upward elastic member 45 resets and drives the pressing seat 42 to drive the movable pressing head 41 on the pressing seat 42 to move away from the fixed pressing head 43 to release the disc 10. The movable seat 21 continues to be driven by the inlet / outlet driving member 31 and will move along the track guiding plate 16 to the first position 11. The centrifugal pressing assembly 4 of the present invention is disposed at the second position 12 and will not move with the tray assembly 2 between the first position 11 and the second position 12. The centrifugal driving member 44 is fixedly disposed at the second position 12, which can prevent the sample centrifugation mechanism from generating large vibrations and noises when centrifuging the sample on the disc 10; moreover, the inlet / outlet of the tray assembly 2 is realized through the inlet / outlet assembly 3, so that the overall left and right dimensions of the sample centrifugation mechanism can be significantly reduced compared with other instruments, saving space and reducing weight.

[0054] Among them, in one embodiment, a track guide plate 16 slidably connected to the movable seat 21 is provided on the bracket 1. The loading and unloading assembly 3 further includes a swing fork 32 movably connected to the bracket 1 and the movable seat 21 respectively. The loading and unloading driving member 31 is used to drive the swing fork 32 to drive the movable seat 21 to move between the first position 11 and the second position 12. When the movable seat 21 is located at the second position 12, the loading and unloading driving member 31 is further used to drive the movable seat 21 to drive the pressing seat 42 to move relative to the bracket 1 through the swing fork 32, so as to drive the movable pressing head 41 to approach the fixed pressing head 43 and press the disc 10. Please refer to Figure 4 As shown, when the disc 10 needs to be placed on the movable seat 21, the loading and unloading driving member 31 drives the swing fork 32 to drive the movable seat 21 to move from the second position 12 to the first position 11. At this time, the swing fork 32 is located at the first position, and when the disc 10 pops out of the magazine, the swing fork 32 swings to the outermost position outside the magazine; Please refer to Figure 9 As shown, when the movable seat 21 needs to move from the first position 11 to the second position 12, the loading and unloading driving member 31 drives the swing fork 32 to drive the movable seat 21 to move from the first position 11 to the second position 12. At this time, the swing fork 32 is located at the second position, the disc 10 retracts into the magazine but is not pressed, and the movable seat 21 is disengaged from the pressing seat 42; Please refer to Figure 13 As shown, when the disc 10 needs to be pressed, the loading and unloading driving member 31 continues to drive the swing fork 32 and drives the movable seat 21 to move, so that the movable seat 21 is engaged with the pressing seat 42. The loading and unloading driving member 31 then continues to drive the swing fork 32 and drives the movable seat 21 to move, and drives the movable pressing head 41 to approach the fixed pressing head 43 through the pressing seat 42 to press the disc 10. At this time, the swing fork 32 is located at the third position, and the disc 10 is pressed by the pressing assembly at the second position 12. The loading and unloading assembly 3 uses the swing fork 32 to amplify the stroke to realize the loading and unloading movement of the disc 10.

[0055] Furthermore, please combine Figure 6 、 Figure 9 、 Figure 13As shown, the trajectory guide plate 16 has a trajectory groove 161. The movable seat 21 is provided with a guide groove 214 and a tracking pin 211 inserted into the guide groove 214. The tracking pin 211 is also inserted into the trajectory groove 161 and is slidably connected to the groove wall of the trajectory groove 161, and is movably connected to the end of the swing fork 32 away from the bracket 1. The in-out driving member 31 is used to drive the swing fork 32 to move along the trajectory groove 161. The pressing seat 42 is provided with a clutch clamping groove 423. When the movable seat 21 is located at the second position 12, the tracking pin 211 is snapped into the clutch clamping groove 423. The trajectory groove 161 restricts the movement of the tracking pin 211. The guide groove 214 is opened in the vertical direction to limit the up-and-down movement of the tracking pin 211 along it. The tracking pin 211 can realize the horizontal in-out movement of the disc 10 and the up-and-down pressing and disengaging movement. The tracking pin 211 is coaxially rotatably connected to the hole at the upper end of the swing fork 32, and can move up and down along the guide groove 214 and move along the constrained trajectory of the trajectory groove 161. When the disc 10 is retracted into the chamber, the tracking pin 211 is horizontally snapped into the clutch clamping groove 423 of the pressing assembly, driving the pressing assembly to move up and down. Moreover, the clutch clamping groove 423 is a U-shaped notch facing horizontally outwards. When the disc 10 is retracted into the chamber, the protruding end of the tracking pin 211 will horizontally enter the groove, and the two cannot move relative to each other in the up-and-down direction.

[0056] In addition, please refer to Figure 5 As shown, in an embodiment, the trajectory groove 161 includes a horizontally connected horizontal trajectory groove 1611 and a vertical trajectory groove 1612. The in-out driving member 31 is used to drive the swing fork 32 to drive the movable seat 21 to move between the first position 11 and the second position 12 along the horizontal trajectory groove 1611. The in-out driving member 31 is used to drive the swing fork 32 to drive the movable pressing head 41 to approach the fixed pressing head 43 through the pressing seat 42 to press the disc 10 along the vertical trajectory groove 1612. When the swing fork 32 swings, the tracking pin 211 will move along the downward part of the trajectory groove 161, thereby driving the pressing assembly to move in the up-and-down direction to realize the pressing and disengaging of the disc 10.

[0057] Among them, please refer to Figure 3As shown, round holes and waist-shaped holes are respectively formed at both ends of the swing fork 32. The tracking pin 211 is inserted into the round hole. A fixing pin 13 is provided on the bracket 1, and a power pin 311 is provided on the in-out driving member 31. Both the fixing pin 13 and the power pin 311 are inserted into the waist-shaped hole. The fixing pin 13 is fixed on the bracket 1. The in-out driving member 31 drives the swing fork 32 through the power pin 311. The swing fork 32 swings around the fixing pin 13 and drives the movable seat 21 to move through the tracking pin 211, so that the movable seat 21 can move between the first position 11 and the second position 12. Moreover, since both the fixing pin 13 and the power pin 311 are inserted into the waist-shaped hole, the swing fork 32 can amplify the stroke of the movable seat 21. It should be noted that the position of the power pin 311 can be arranged according to the actual situation. The power pin 311 can be located between the tracking pin 211 and the fixing pin 13, or can be located below the tracking pin 211 and the fixing pin 13, etc.

[0058] Further, please refer to Figure 4 、 Figure 9 and Figure 13As shown in the figure, in order to achieve multiple functions, the tray assembly 2 further includes a tray 22 provided on the movable seat 21. A lifting elastic member 221 is connected between the tray 22 and the movable seat 21. The disc 10 is placed on the tray 22. A pull rod 222 with a clamping portion 2221 is provided on the tray 22. A downward pull slot 421 for clamping with the pull rod 222 is provided on the pressing seat 42. When the movable seat 21 is located at the second position 12, the clamping portion 2221 is clamped with the downward pull slot 421. When the disc 10 is pressed, the inlet and outlet driving member 31 is further configured to drive the movable seat 21 to drive the pressing seat 42 to move relative to the bracket 1 through the swing fork 32, so as to drive the tray 22 to move relative to the movable seat 21 and separate the tray 22 from the disc 10. When the disc 10 retracts into the chamber, the downward pull slot 421 is clamped with the T-shaped convex disc at the bottom of the pull rod 222 of the tray 22, so that the tray 22 can be driven to move up and down by the pressing seat 42. When the pressing seat 42 moves downward, the tray 22 can be pulled downward, causing the lifting elastic member 221 to deform under force; when the movable seat 21 leaves the second position 12, the pull rod 222 is disengaged from the downward pull slot 421, and the lifting elastic member 221 returns to its original state when not under external force, causing the tray 22 to be lifted until the tray 22 is pulled downward again and the lifting elastic member 221 is deformed by force again. The tray 22 carrying the disc 10 can enter and exit the chamber along the guide rail and simultaneously move up and down along the axial direction of the pull rod 222, so that the centrifuge disc can complete the actions of entering and exiting the chamber and pressing and separating up and down; the pressing assembly pulls the tray 22 downward to make the disc 10 achieve the pressing and separating actions relative to the fixed pressing head 43, and at the same time drives the movable pressing head 41 to press the disc 10 from the upper surface of the disc 10 together. Moreover, since the tray 22 is pulled downward and separated from the disc 10, the disc 10 is in a suspended state, which can greatly reduce the centrifugal mass and the centrifugal resistance, increase the centrifugal speed, reduce the centrifugal time, and thus avoid the problem that emergency samples cannot be inserted for centrifugation during the operation of the centrifuge.

[0059] In addition, in the above embodiments, a guiding seat 212 is provided on the movable seat 21. The guiding seat 212 is provided with a guiding hole, and the pull rod 222 is inserted into the guiding hole. The lifting elastic member 221 is a spring, and the lifting elastic member 221 is sleeved on the outer periphery of the pull rod 222. The guiding hole is used to accommodate the lifting elastic member 221. In order to protect the lifting elastic member 221 and make the direction in which the tray 22 is lifted more accurate, a guiding seat 212 can be provided on the movable seat 21. The guiding seat 212 has a vertically opened guiding hole. The pull rod 222 is inserted into the guiding hole, and the lifting elastic member 221 is sleeved on the outer periphery of the pull rod 222. A guiding space for accommodating the lifting elastic member 221 is formed between the guiding hole and the pull rod 222. When the lifting elastic member 221 is in a compressed state, it can be accommodated in the guiding space, thereby protecting the lifting elastic member 221. When the lifting elastic member 221 returns to its original state, it can also move along the guiding space, which is beneficial to the stability when the tray 22 is lifted. In order to stably pull down and lift the tray 22, the number of pull rods 222 is 3. The 3 pull rods 222 are arranged in an equilateral triangle shape. The number of the lifting elastic members 221 and the guiding seats 212 is the same as that of the pull rods 222 and they are arranged in one-to-one correspondence.

[0060] Wherein, a retaining wall 223 is formed by the outer edge of the tray 22 protruding upward. The retaining wall 223 and the bottom wall of the tray 22 enclose a receiving space 2231 for receiving the disc 10. In order to prevent the disc 10 from sliding out of the tray 22 when entering and leaving the magazine, a retaining wall 223 can be provided around the bottom wall of the tray 22. The retaining wall 223 and the bottom wall of the tray 22 enclose a receiving space 2231 for receiving the disc 10. The retaining wall 223 can limit the disc 10 in the horizontal direction.

[0061] Furthermore, in order to achieve multiple functions, a first connecting member 213 is provided at the bottom of the movable seat 21, and a second connecting member 14 is provided on the bracket 1. The first connecting member 213 is movably connected to the second connecting member 14. In one embodiment, the movable seat 21 and the bracket 1 are slidably connected. In order to ensure that the movable seat 21 can accurately reach the first position 11 and the second position 12, first connecting members 213 are provided at both opposite ends of the bottom of the movable seat 21. A second connecting member 14 is provided on the bracket 1. The number of the second connecting members 14 is the same as that of the first connecting members 213 and they are slidably connected in one-to-one correspondence. The connection between the first connecting member 213 and the second connecting member 14 can adopt rolling connection, the cooperation connection of a slide rail and a slider, belt connection, a sliding rod and a connecting member, etc.

[0062] In addition, in the above embodiments, the first connecting member 213 includes a first sub-guide rail 2131 and a second sub-guide rail 2132 that are slidably connected to each other. The first sub-guide rail 2131 is connected to the movable seat 21, and the second sub-guide rail 2132 is slidably connected to the second connecting member 14. When the second position 12 and the first position 11 are at a relatively large distance from each other, the first connecting member 213 or the second connecting member 14 can be set as a multi-stage telescopic guide rail. In one embodiment, the first connecting member 213 includes a first sub-guide rail 2131 and a second sub-guide rail 2132 that are slidably connected to each other. Among them, the first sub-guide rail 2131 is connected to the movable seat 21, and the second sub-guide rail 2132 is slidably connected to the second connecting member 14. When the movable seat 21 moves from the second position 12 to the first position 11, the second sub-guide rail 2132 slides outwards relative to the second connecting member 14, and the first sub-guide rail 2131 slides outwards relative to the second sub-guide rail 2132. When the movable seat 21 retracts, the reverse action is performed. The multi-stage telescopic guide rail guides the disc 10 in and out of the magazine, and the total travel length is greater than the total length of the guide rail when retracted.

[0063] Furthermore, the first position 11 is an out-of-magazine position, and the second position 12 is an in-magazine position. In this embodiment, the in-out driving member 31 can drive the tray assembly 2 to move between the out-of-magazine position and the in-magazine position, so that the disc 10 placed on the tray assembly 2 can reach the in-magazine position, and the centrifugal pressing assembly 4 centrifugally presses the disc 10 at the in-magazine position, so that the disc 10 does not need off-machine centrifugation.

[0064] Furthermore, a transmission member 33 is connected between the in-out driving member 31 and the swing fork 32. In one embodiment, the transmission member 33 includes a lead screw 331 and a lead screw nut seat 332 provided on the lead screw 331. The drive shaft of the in-out driving member 31 is connected to the lead screw 331. A power pin 311 is provided on the lead screw nut seat 332. The in-out magazine lead screw 331 motor pushes the lead screw nut seat 332 to move back and forth, so that the swing fork 32 can be driven to swing through the power pin 311 on the lead screw nut seat 332, thereby realizing the in-out of the tray assembly 2. In another embodiment, the transmission member 33 includes two racks arranged at intervals up and down and a gear provided between the two racks and meshing with both racks. Among them, the upper rack is provided on the tray assembly 2, and the lower rack is provided on the bracket 1. The drive shaft of the in-out driving member 31 is coaxially connected to the gear. The motor drives the gear to rotate, so that the motor and the gear move in the horizontal direction, and drive the upper rack to move relative to the rack on the bracket 1, so that the stroke of the tray assembly 2 relative to the bracket 1 is doubled, so as to realize the in-out of the tray assembly 2.

[0065] In addition, the present invention also provides a sample analyzer, which includes a housing and the above-described sample centrifugation mechanism housed in the housing. For the specific structure of the sample centrifugation mechanism in this sample analyzer, reference may be made to the above embodiments. Since this sample analyzer adopts all the technical solutions of the above embodiments, it has at least all the beneficial effects brought by the technical solutions of the above embodiments, which will not be elaborated herein one by one.

[0066] The sample analyzer in the present invention can eliminate the operation that the user needs to centrifuge the whole blood sample, avoiding cumbersome operations; it can avoid the biosafety risk of opening the lid outside the machine; it can shorten the waiting and transfer time from the centrifuge to the instrument, improving the speed of obtaining results for emergency samples; it can avoid the vibration and noise of the centrifuge; it can eliminate the cost and floor space of the centrifuge; compared with the existing centrifugal disk centrifugation component, the design of the centrifugal pressing component 4 can avoid precise transmissions such as the repeatedly meshing gear transmission between the centrifugal disk and the centrifugal motor, thereby reducing the manufacturing difficulty and cost of the sample centrifugation mechanism.

[0067] The above are only the preferred embodiments of the present invention, and do not limit the patent scope of the present invention accordingly. Any equivalent structural transformation made by using the content of the specification and drawings of the present invention under the inventive concept of the present invention, or direct / indirect application in other related technical fields is included in the patent protection scope of the present invention.

Claims

1. A sample centrifugation mechanism, characterized in that, Comprising: A bracket, provided with a first position and a second position at intervals; A tray assembly, including a movable seat for supporting a disc, and the movable seat is slidably connected to the bracket; An inlet / outlet assembly, including an inlet / outlet driving member for driving the movable seat to move between the first position and the second position; A centrifugal pressing assembly, arranged at the second position, and including a movable pressing head, a pressing seat, a pressing driving member, a fixed pressing head and a centrifugal driving member. The movable pressing head is rotatably connected to the pressing seat, the fixed pressing head is connected to the centrifugal driving member, the movable pressing head and the fixed pressing head are arranged corresponding to each other, at least one of the movable pressing head and the fixed pressing head is a magnetic member and they attract each other, and the pressing seat is movably connected to the bracket; When the movable seat is at the second position, the pressing driving member is used to drive the pressing seat to move relative to the bracket, so as to drive the movable pressing head to approach the fixed pressing head and press the disc, and the centrifugal driving member is used to drive the fixed pressing head to rotate the disc; The pressing driving member is shared with the inlet / outlet driving member, and an upward elastic member is connected between the pressing seat and the bracket. When the movable seat is at the second position, the movable seat is clamped with the pressing seat, and the inlet / outlet driving member is further used to drive the movable seat to drive the pressing seat to move relative to the bracket, so as to drive the movable pressing head to approach the fixed pressing head and press the disc, and the centrifugal driving member is used to drive the fixed pressing head to rotate the disc; A trajectory guiding plate slidably connected to the movable seat is arranged on the bracket. The inlet / outlet assembly further includes a swing fork movably connected to the bracket and the movable seat respectively. The inlet / outlet driving member is used to drive the swing fork to drive the movable seat to move between the first position and the second position. When the movable seat is at the second position, the inlet / outlet driving member is further used to drive the movable seat to drive the pressing seat to move relative to the bracket through the swing fork, so as to drive the movable pressing head to approach the fixed pressing head and press the disc; The trajectory guiding plate has a trajectory groove. A guiding groove is arranged on the movable seat, and a tracing pin inserted into the guiding groove is also inserted into the trajectory groove and slidably connected to the groove wall of the trajectory groove, and is movably connected to the end of the swing fork away from the bracket. The inlet / outlet driving member is used to drive the swing fork to move along the trajectory groove. A clutch clamping groove is arranged on the pressing seat. When the movable seat is at the second position, the tracing pin is clamped into the clutch clamping groove; The trajectory groove includes a horizontally connected horizontal trajectory groove and a vertical trajectory groove. The inlet / outlet driving member is used to drive the swing fork to drive the movable seat to move between the first position and the second position along the horizontal trajectory groove, and the inlet / outlet driving member is used to drive the swing fork to drive the movable pressing head to approach the fixed pressing head to press the disc through the pressing seat along the vertical trajectory groove.

2. The sample centrifugation mechanism according to claim 1, wherein, The disc is provided with a through hole. The fixed pressure head and the movable pressure head both abut against the through hole and have a gap therebetween to press the disc tightly. The movable seat is provided with an avoidance groove, and the tray is provided with an avoidance hole. The avoidance groove and the avoidance hole are both used to avoid the fixed pressure head.

3. The sample centrifugation mechanism according to claim 2, characterized in that, The fixed pressure head includes a pressure head bracket and a pressing magnet. The pressure head bracket is provided with a mounting hole, and the pressing magnet is embedded in the mounting hole. The movable pressure head is a magnetic pressure head attracted to the pressing magnet. The pressing seat is provided with a mounting plate, and the movable pressure head is rotatably arranged on the mounting plate. A protruding shaft is arranged on one side of the movable pressure head corresponding to the fixed pressure head. The protruding shaft is used to insert into the mounting hole. The pressing magnet and the protruding shaft both abut against the through hole and have a gap therebetween to press the disc tightly. When the disc is pressed tightly, the pressing driving member is further used to drive the pressing seat to move relative to the bracket, so that there is a gap between the mounting plate and the movable pressure head in the up and down direction.

4. The sample centrifugation mechanism according to claim 1, characterized in that, The bracket is provided with a slide rail extending in the vertical direction, and the pressing seat is provided with a chute slidably connected to the slide rail.

5. The sample centrifugation mechanism according to claim 1, characterized in that, Both ends of the swing fork are respectively provided with a round hole and an oval hole. The tracking pin is inserted into the round hole. The bracket is provided with a fixed pin, and the inlet and outlet driving member is provided with a power pin. The fixed pin and the power pin are both inserted into the oval hole.

6. A sample analyzer, characterized in that, The sample analyzer includes a housing and a sample centrifugation mechanism as described in any one of claims 1 to 5 accommodated in the housing.

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