A method for drawing and interpreting real-time three-dimensional volume loop of left atrium and ventricle

Abstract

The present invention discloses a method for drawing and interpreting a real-time three-dimensional volume loop of the left atrium and ventricle, and belongs to the field of cardiac ultrasound. The method of the present invention comprises the following steps: S1, image retention: using a Philips echocardiogram instrument with a Philips Heart Model mode and equipped with an X5-1 probe to use the Heart Model mode to retain images of at least 6 cardiac cycles on the apical four-chamber section; S2, software analysis: analyzing the retained images to obtain a real-time synchronized three-dimensional volume curve of the left atrium and left ventricle; S3, point drawing: the corresponding left atrium and left ventricle volumes taken at different times on the three-dimensional volume curve in the software are drawn with the left ventricle volume as the X-axis and the left atrium volume as the Y-axis; the present invention can easily judge the left atrium and ventricle function and the left atrium and ventricle relationship through the real-time synchronized left atrium and ventricle volume curve, can identify abnormal heart function that cannot be identified by conventional echocardiogram, and avoid fragmented analysis of the left atrium and ventricle function; high repeatability and no harm to the human body.

Description

Technical Field

[0001] The invention relates to the field of cardiac ultrasound, and in particular to a method for drawing and interpreting a real-time three-dimensional volume loop of a left atrium and chamber. Background Art

[0002] Whether it is traditional two-dimensional ultrasound or novel three-dimensional ultrasound, it cannot quantitatively and real-time reflect the relationship between the left atrium and ventricle, but the left atrium and ventricle are an interrelated system, divided only by the atrioventricular valve, and the roles and functions between them are highly related. Therefore, in current medical practice, we urgently need a method to reflect the real-time synchronous functional changes of the left atrium and ventricle to guide our understanding of the occurrence and development of heart disease. Summary of the invention

[0003] In view of the deficiencies of the prior art, the present invention proposes a method for drawing and interpreting a real-time three-dimensional volume loop of the left atrium and ventricle.

[0004] The purpose of the present invention can be achieved through the following technical solutions:

[0005] A method for drawing a left atrium and chamber real-time three-dimensional volume loop comprises the following steps:

[0006] Connect the ECG leads of the echocardiogram instrument to both upper limbs and left lower limb of the subject to be examined and form a recognizable ECG;

[0007] Adjust the ultrasound window, select a relatively clear apical four-chamber view, and adjust the instrument to achieve the best image quality;

[0008] According to the cardiac cycle identified by the electrocardiogram, complete images of several cardiac cycles in the electrocardiogram are retained;

[0009] Draw a left atrium and chamber three-dimensional volume curve according to the electrocardiogram,

[0010] According to the left atrium and ventricle three-dimensional volume curve, the synchronized left atrium and ventricle three-dimensional volumes are recorded at specific time points, the body surface area is calculated according to the height and weight of the subject, and the left atrium and ventricle three-dimensional volumes are divided by the body surface area for standardization, and the left atrium volume index and left ventricle volume index of each node in a single cardiac cycle are obtained;

[0011] The obtained one-to-one corresponding left atrial volume index and left ventricular volume index are used as the Y-axis and X-axis respectively, and each node in a single cardiac cycle is connected by a curve to draw a circular curve with a closed beginning and end.

[0012] Optionally, drawing the left atrium and ventricle three-dimensional volume curve according to the electrocardiogram comprises the following steps:

[0013] The retained three-dimensional cardiac ultrasound image data is transferred to the QLAB ultrasound workstation;

[0014] The three-dimensional cardiac ultrasound image was opened in the QLAB ultrasound workstation, and the cardiac cycle was selected for image analysis using the DHM mode. After the analysis, the heart boundary was manually adjusted to obtain the three-dimensional volume curves of the left atrium and ventricle at different time nodes in a single cardiac cycle.

[0015] Optionally, the cardiac ultrasound instrument is a Philips Heart Model cardiac ultrasound instrument equipped with a three-dimensional X5-1 cardiac probe.

[0016] In addition, the present invention also relates to an analysis method for the above three-dimensional volume ring, comprising the following steps:

[0017] Establish a standard 3D volume ring or a reference 3D volume ring,

[0018] Recording the degree of upward or downward movement of the three-dimensional volume loop to be analyzed relative to the standard three-dimensional volume loop or the reference three-dimensional volume loop, to characterize the relative change of the left atrial volume index in the whole cardiac cycle;

[0019] The degree of leftward or rightward shift of the three-dimensional volume loop to be analyzed relative to the standard three-dimensional volume loop or the reference three-dimensional volume loop is recorded to characterize the relative change of the left ventricular volume index in the whole cardiac cycle.

[0020] The standard three-dimensional volume ring may be a three-dimensional volume ring obtained by the above-mentioned drawing method using healthy people as samples. The reference three-dimensional volume ring may be a three-dimensional volume ring obtained by the above-mentioned drawing method at different periods or different physiological states of the same test subject. The reference three-dimensional volume ring may also be a three-dimensional volume ring obtained by the above-mentioned drawing method for any test subject that is expected to be used as a reference.

[0021] A three-dimensional volume ring drawing device, comprising:

[0022] The data acquisition module inputs the collected electrocardiogram wires of both upper limbs and left lower limb connected to the echocardiogram instrument and forms a recognizable electrocardiogram;

[0023] A data processing module receives the electrocardiogram in the data acquisition module, forms a left atrium and chamber three-dimensional volume curve based on the electrocardiogram, and further processes to obtain a left atrial volume index and a left ventricular volume index;

[0024] The image drawing module can use the left atrial volume index and the left ventricular volume index as the Y axis and the X axis respectively, connect each node in a single cardiac cycle with a curve, and draw the three-dimensional volume ring.

[0025] Beneficial effects of the present invention:

[0026] The present invention draws a volume ring using the left atrium and ventricle volume obtained through real-time three-dimensional echocardiography. The left atrium and ventricle function and the left atrium and ventricle relationship can be easily determined based on the morphological characteristics of the volume ring, thereby providing a more accurate reference index for abnormal cardiac function and avoiding fragmented analysis of the left atrium and ventricle function. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] The present invention will be further described below in conjunction with the accompanying drawings.

[0028] Figure 1 It is a schematic diagram of the ultrasonic image retention image of the present invention;

[0029] Figure 2 is a schematic diagram of a three-dimensional echocardiogram retained by the present invention;

[0030] Figure 3 It is a schematic diagram of the DHM software analysis of the present invention;

[0031] Figure 4 It is a curve diagram of the left atrium and ventricle volume index after point standardization of the present invention;

[0032] Figure 5 is an example diagram of the left atrioventricular volume loop in the present invention;

[0033] Figure 6 It is a schematic diagram of the up and down movement of the left atrium-ventricle volume loop in the present invention;

[0034] Figure 7 It is a schematic diagram of the left and right movement of the left atrium-ventricle volume ring in the present invention. DETAILED DESCRIPTION

[0035] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0036] The present application discloses a method for drawing a real-time three-dimensional volume loop of a left atrium and ventricle.

[0037] S1. Select an echocardiogram instrument with Philips Heart Model mode and equip it with a three-dimensional X5-1 cardiac probe. Connect the electrocardiogram wires that come with the echocardiogram instrument to the upper limbs and left lower limb of the target to form a recognizable electrocardiogram image. Adjust the ultrasound window, select a relatively clear apical four-chamber section, and adjust the instrument to achieve the best image quality. According to the cardiac cycle identified by the electrocardiogram, retain the complete image of 6 cardiac cycles. The specific process is as follows: Figure 1 shown.

[0038] S2. The retained 3D cardiac ultrasound image data is transferred offline to the QLAB ultrasound workstation in DICOM format. Figure 1 The three-dimensional cardiac ultrasound image shown in the figure uses the DHM mode to select the appropriate cardiac cycle to perform intelligent analysis on the image. After the intelligent analysis is completed, the range of the heart boundary is manually adjusted. If satisfactory, the three-dimensional volume curve of the left atrium and ventricle at different time nodes in a single cardiac cycle is obtained. Specifically, Figure 2 .

[0039] S3. According to Figure 3 The DHM analysis shown in the figure obtains the left atrium and ventricle three-dimensional volume curve, and records the synchronized left atrium and left ventricle three-dimensional volumes at specific time points. For example, the recording can be performed at equal time intervals within the cardiac cycle. For another example, the left atrium and left ventricle three-dimensional volumes at the beginning of contraction, 25%, 50%, 75% of contraction, end of contraction, 25%, 50%, 75% of diastole, and end of diastole are recorded. The body surface area is calculated based on the height and weight of the subject, and the three-dimensional volume of the left atrium and ventricle is divided by the body surface area for standardization, to obtain the following: Figure 4 Left atrial ventricular volume index at each node during a single cardiac cycle is shown.

[0040] The corresponding left atrial volume index and left ventricular volume index are used as the Y-axis and X-axis respectively. Each node has an independent point. The nodes are connected with a smooth curve to draw the following figure: Figure 5 The circular curve shown is closed at both ends.

[0041] S4, such as Figure 6 As shown in the figure, the overall upward shift of the curve indicates that the left atrial volume index of the whole cardiac cycle is larger, indicating a larger atrial volume, which is related to worse left ventricular diastolic function. Correspondingly, the overall downward shift of the curve indicates that the left atrial volume index of the whole cardiac cycle is smaller, indicating a smaller atrial volume. Figure 7 As shown in the figure, the left shift of the curve indicates a decrease in the left ventricular volume index, while the right shift indicates an increase in the left ventricular volume index. The width between the systolic curve and the diastolic curve is related to the stroke volume. The wider it is, the greater the stroke volume in a single cardiac cycle may be. The slope of the left atrioventricular volume loop is obtained by dividing the change in atrial volume by the change in ventricular volume. While reflecting the change in atrioventricular volume, it can also indirectly reflect the peripheral vascular pressure, left ventricular contractility, and the degree of matching between venous return and cardiac output.

[0042] In addition, it should be noted that the above-mentioned vessel loop curve can provide a new and intuitive evaluation method, which is of reference significance in the study of heart and its diseases, but its analysis or evaluation results cannot be directly associated with specific heart diseases.

[0043] In the description of this specification, the description with reference to the terms "one embodiment", "example", "specific example", etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0044] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments, and the above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, and these changes and improvements all fall within the scope of the present invention to be protected.

Claims

1. A method for drawing a real-time three-dimensional volume loop of a left atrium and ventricle, characterized in that: The following steps are involved: Connect the ECG leads of the echocardiogram instrument to the upper limbs and left lower limb of the subject to be examined and form a recognizable ECG; According to the cardiac cycle identified by the electrocardiogram, complete images of several cardiac cycles in the electrocardiogram are retained; Draw a left atrium and chamber three-dimensional volume curve according to the electrocardiogram, According to the left atrium and chamber three-dimensional volume curve, the synchronized left atrium three-dimensional volume and left ventricle three-dimensional volume were recorded, the body surface area was calculated according to the height and weight of the subject, and the left atrium and chamber three-dimensional volume were divided by the body surface area for standardization, and the left atrium volume index and left ventricle volume index of each node in a single cardiac cycle were obtained; The obtained one-to-one corresponding left atrial volume index and left ventricular volume index are used as the Y axis and X axis respectively, and each node in a single cardiac cycle is connected by a curve to draw the three-dimensional volume ring.

2. The method for drawing a left atrium and ventricle real-time three-dimensional volume loop according to claim 1, characterized in that: The method of drawing the left atrium and ventricle three-dimensional volume curve according to the electrocardiogram comprises the following steps: The retained three-dimensional cardiac ultrasound image data is transferred to the QLAB ultrasound workstation; The three-dimensional cardiac ultrasound image was opened in the QLAB ultrasound workstation, and the cardiac cycle was selected for image analysis using the DHM mode. After the analysis, the heart boundary was manually adjusted to obtain the three-dimensional volume curves of the left atrium and ventricle at different time nodes in a single cardiac cycle.

3. The method for drawing a left atrium and ventricle real-time three-dimensional volume loop according to claim 1, characterized in that: The cardiac ultrasound instrument is a cardiac ultrasound instrument with Philips Heart Model mode and is equipped with a three-dimensional X5-1 cardiac probe.

4. A computer-readable storage medium storing instructions, characterized in that: When the instruction is executed, the drawing method described in any one of claims 1 to 3 can be implemented.

5. A method for analyzing a three-dimensional volume loop drawn by the left atrium-ventricle real-time three-dimensional volume loop drawing method according to any one of claims 1 to 3, characterized in that: The following steps are involved: Establish a standard 3D volume ring or a reference 3D volume ring, Recording the degree of upward or downward movement of the three-dimensional volume loop to be analyzed relative to the standard three-dimensional volume loop or the reference three-dimensional volume loop, to characterize the relative change of the left atrial volume index in the whole cardiac cycle; The degree of leftward or rightward shift of the three-dimensional volume loop to be analyzed relative to the standard three-dimensional volume loop or the reference three-dimensional volume loop is recorded to characterize the relative change of the left ventricular volume index in the whole cardiac cycle.

6. The analysis method according to claim 5, characterized in that Also includes the steps: The slope of the three-dimensional volume loop is recorded to characterize the change in atrioventricular volume, as well as the matching degree of peripheral vascular pressure, left ventricular contractility, and venous return with cardiac output.

7. A computer-readable storage medium storing instructions, characterized in that: When the instructions are executed, the analysis method described in claim 5 or 6 can be implemented.

8. A three-dimensional volume ring drawing device, comprising: The data acquisition module inputs the collected electrocardiogram wires of both upper limbs and left lower limb connected to the echocardiogram instrument and forms a recognizable electrocardiogram; A data processing module receives the electrocardiogram in the data acquisition module, forms a left atrium and chamber three-dimensional volume curve based on the electrocardiogram, and further processes to obtain a left atrial volume index and a left ventricular volume index; The image drawing module can use the left atrial volume index and the left ventricular volume index as the Y axis and the X axis respectively, connect each node in a single cardiac cycle with a curve, and draw the three-dimensional volume ring.

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