Powder-liquid mixing device

Abstract

This invention discloses a powder-liquid mixing device, comprising: a mixing valve, and a powder cylinder system, a liquid medicine cylinder system, and a support plate disposed on the mixing valve. The powder cylinder system includes a powder cylinder for filling with powder, and the liquid medicine cylinder system is used for adding liquid medicine. The powder-liquid mixing device of this invention mainly utilizes the separate storage of powders, followed by their coordinated movement to form a high-speed fluid of liquid medicine, achieving high-speed impact of the liquid medicine on the powder, fully dispersing the powder, and achieving more efficient fusion, thus reaching a high-viscosity fusion.

Description

Technical Field

[0001] This invention relates to the field of mechatronics, and in particular to a powder-liquid mixing device. Background Technology

[0002] This powder-liquid mixer is suitable for efficient batch mixing of powders and liquids. It employs a novel solid-liquid mixing concept, integrating all traditional solid-liquid mixing steps into a single device. This ensures more uniform powder introduction and mixing with the liquid, eliminating incompletely wetted powder and preventing powder agglomeration on the liquid surface, stirring shaft, and container walls. It completely solves the processing challenges of high-viscosity products (million-centipoise) that traditional equipment struggles with, significantly improving product quality. It can meet various production capacity requirements and is designed and manufactured according to cGMP standards.

[0003] – The integrated design of the Class D background ensures good self-cleaning performance in mixed spaces;

[0004] – The drive system, components, and maintenance are completely isolated from Zone D, which further reduces operating costs;

[0005] – The main drive adopts servo control, which can mix according to the speed and propulsion distance required by the process, with high repeatability and stable and reliable mixing effect.

[0006] The mixing channel adopts the working principle of a Laval nozzle, consisting of two conical tubes, one a contraction tube and the other an expansion tube. This ensures that the liquid is sprayed into the powder cylinder at a high velocity, so that the powder is instantly and uniformly wetted upon first contact with the liquid, resulting in rapid and uniform dispersion. This avoids the agglomeration phenomenon that occurs when powder encounters liquid in traditional processes, thus eliminating the need for a slow deagglomeration process, improving production efficiency, and making it particularly suitable for the dispersion of nanoscale powders.

[0007] – The three-way valve is controlled by a stepper motor to ensure that the opening speed and angle of the three-way valve can be performed according to process requirements.

[0008] – The servo-driven electric cylinder mixing mode ensures that the solution has a high viscosity even when the powder is saturated with high solids content materials. Ordinary mixing equipment often takes a long time or requires an additional disperser because it cannot achieve good deagglomeration.

[0009] – The mixing drum can be quickly disassembled and installed without the use of tools;

[0010] - An independent vacuum pump is used for vacuuming to ensure process requirements are met.

[0011] - The process control is stable and complies with GAMP5 and 21 CFR Part 11 requirements. Summary of the Invention

[0012] To overcome the shortcomings of the prior art, the present invention provides a powder-liquid mixing device to achieve the goal of quickly and uniformly mixing powder and liquid medicine.

[0013] The technical solution adopted in this invention is: a powder-liquid mixing device, comprising: a powder cylinder system, a liquid cylinder system, a mixing valve, and a support plate, characterized in that: the powder cylinder system includes a powder cylinder and a powder piston slidably fitted on the powder cylinder, the right end of the powder cylinder being connected to the mixing valve; the liquid cylinder system includes a liquid cylinder and a liquid piston slidably fitted on the liquid cylinder, the left end of the liquid cylinder being connected to the mixing valve; both the powder cylinder and the liquid cylinder are horizontally arranged on the support plate, and the powder cylinder communicates with the liquid cylinder through the mixing valve to perform high-viscosity mixing of powder and liquid.

[0014] Preferably, the powder cylinder system includes:

[0015] A left-side electric cylinder is connected to the powder piston, and the left-side electric cylinder controls the powder piston to slide left and right inside the powder cylinder;

[0016] A powder device support, including a left handle, wherein the left electric cylinder is placed on the powder device support;

[0017] A left-side dovetail guide plate is provided. The powder device bracket is connected to the support plate through the left-side dovetail guide plate. The left-side handle controls the movement distance of the powder device bracket on the left-side dovetail guide plate.

[0018] Preferably, the powder cylinder system further includes a left self-locking rotary plunger, which is fixedly mounted on the powder device bracket and connected to the left end of the powder cylinder; the left end of the powder piston passes through the left self-locking rotary plunger and is connected to the left electric cylinder, which is coaxially mounted with the powder piston.

[0019] Preferably, the left self-locking rotary plunger includes a left self-locking knob, which controls the locking and unlocking of the left self-locking rotary plunger with the powder cylinder.

[0020] Preferably, the left-side electric cylinder includes:

[0021] A left-side electric cylinder chamber provides power for the piston movement of the powder material;

[0022] A left-side electric cylinder piston rod is located inside the left-side electric cylinder cavity. The right end of the left-side electric cylinder piston rod is connected to the powder piston. The left-side electric cylinder piston rod is coaxially arranged with the powder cylinder body.

[0023] Preferably, the liquid cylinder system further includes a left connecting member, which connects the left electric cylinder piston rod and the powder piston respectively, and the left connecting member is coaxially arranged with the powder cylinder.

[0024] Preferably, the liquid medicine cylinder system includes:

[0025] A right-side electric cylinder is connected to the liquid medicine piston, and the right-side electric cylinder controls the liquid medicine piston to slide left and right inside the liquid medicine cylinder;

[0026] A medicine liquid device support, including a right-side handle, wherein the right-side electric cylinder is placed on the medicine liquid device support;

[0027] A right-side dovetail guide plate is provided, through which the liquid medicine device bracket is connected to the support plate. The right-side handle controls the movement distance of the liquid medicine device bracket on the right-side dovetail guide plate.

[0028] Preferably, the liquid cylinder system further includes a right-side self-locking rotary plunger, which is fixedly mounted on the liquid device bracket and connected to the liquid cylinder; a right-side electric cylinder passes through the right-side self-locking rotary plunger and is connected to the liquid piston, and the right-side electric cylinder is coaxially arranged with the liquid piston.

[0029] Preferably, the right-side self-locking rotary plunger includes a right-side self-locking knob, which controls the locking and unlocking of the right-side self-locking rotary plunger and the liquid cylinder.

[0030] Preferably, the right-side electric cylinder includes:

[0031] A right-side electric cylinder chamber provides power for the piston movement of the liquid medicine.

[0032] A right-side electric cylinder piston rod is located inside the right-side electric cylinder cavity. The right end of the right-side electric cylinder piston rod is connected to the liquid medicine piston. The right-side electric cylinder piston rod is coaxially arranged with the liquid medicine cylinder.

[0033] Preferably, the liquid medicine cylinder system further includes a right-side connector, which connects the right-side electric cylinder piston rod and the liquid medicine piston respectively, and the right-side connector is coaxially arranged with the liquid medicine cylinder.

[0034] Preferably, the mixing valve comprises:

[0035] A mixing hole, wherein the mixing hole, the powder cylinder and the liquid cylinder are located on the same central axis, and the powder cylinder and the liquid cylinder are connected through the mixing hole;

[0036] A flow cutter separates the mixing orifice (left) section and the mixing orifice (right) section;

[0037] A flow-blocking handle is connected to the flow-blocking plate, and the flow-blocking handle controls the flow-blocking plate to open and separate the mixing hole (left) section and the mixing hole (right) section.

[0038] Preferably, the powder cylinder system further includes:

[0039] A replenishment port is provided, which is located on the powder cylinder body, and the powder cylinder body is sealed by a cap.

[0040] A powder replenisher (23) is an external device used in conjunction with the powder cylinder (14), and includes scale lines. The powder is loaded into the powder replenisher in preparation for replenishing the powder.

[0041] A precision balance (22) is an external device used in conjunction with the powder replenisher to weigh the powder in the powder replenisher.

[0042] Preferably, the liquid medicine cylinder system further includes a dosing plunger valve, which is located on the liquid medicine cylinder and is fixedly connected to the liquid medicine cylinder; the liquid medicine enters the liquid medicine cylinder through the dosing plunger valve.

[0043] Preferably, the powder-liquid mixing device further includes a vacuum machine, wherein the vacuum tube is connected to the powder cylinder to evacuate the powder cylinder; the vacuum tube is also connected to the liquid cylinder to evacuate the liquid cylinder.

[0044] Preferably, both the powder cylinder and the liquid cylinder are transparent and can be used to observe the degree of fusion between the powder and the liquid.

[0045] Compared with the prior art, the beneficial effects of the present invention are:

[0046] By utilizing the Larva principle, the liquid medicine is formed into a high-speed fluid, enabling more efficient mixing of liquid medicine and powder.

[0047] The design of the mixing valve enables a stable connection between the powder cylinder system and the liquid cylinder system, while ensuring the sealing of the enclosed space formed by the powder cylinder and the liquid cylinder from the outside environment.

[0048] The left and right self-locking knob plungers are simple in structure and easy to operate, effectively ensuring that the powder cylinder and liquid cylinder remain in a fixed state under the pressure of the left and right electric cylinders. Attached Figure Description

[0049] Figure 1This is a partial structural schematic diagram of the present invention;

[0050] Figure 2 This is a schematic diagram of the overall structure of the present invention.

[0051] Figure 3 This is a partial structural schematic diagram of the present invention;

[0052] Figure 4 This is a schematic diagram of the structure of the powder cylinder;

[0053] Figure 5 This is a schematic diagram of the overall structure of the mixing valve;

[0054] Figure 6 This is a schematic diagram of the mixing valve.

[0055] Figure 7 for Figure 6 A schematic diagram of the structure;

[0056] Figure 8 Flowchart for shut-off of the mixing valve;

[0057] Figure 9 This is a schematic diagram of the powder replenishment weighing of the present invention;

[0058] Figure 10 This is a schematic diagram of the vacuum machine structure of the present invention;

[0059] Figure 11 This is a schematic diagram of another structure of the fine discharge port of the present invention;

[0060] Figure 12 This is a schematic diagram of another structure of the mixing valve.

[0061] Note: 1. Powder cylinder system; 2. Liquid medicine cylinder system; 3. Mixing valve; 4. Vacuum machine; 5. Dosing plunger valve; 6. Left electric cylinder; 7. Right electric cylinder; 8. Left self-locking knob plunger; 9. Right self-locking knob plunger; 10. Powder piston; 11. Liquid medicine piston; 12. Left self-locking knob; 13. Right self-locking knob; 14. Powder cylinder; 15. Replenishment port; 16. Powder device bracket; 17. Left dovetail guide plate; 18. Right dovetail guide plate; 19. Liquid medicine device bracket; 20. Left handle; 21. Right handle; 22. Precision balance; 23. Powder replenisher; 25. Vacuum tube; 26. Mixing hole; 27. Flow cut-off plate; 28. Flow cut-off handle; 31. Replenishment filter element; 33. Liquid medicine cylinder; 34. Left connector; 35. Right connector. Detailed Implementation

[0062] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0063] Please refer to Figures 1 to 2 The powder-liquid mixing device of the present invention includes a powder cylinder system 1, a liquid cylinder system 2, a mixing valve 3, and a support plate. Both the powder cylinder system 1 and the liquid cylinder system 2 are horizontally arranged on the support plate. Through the mixing valve 3, the powder cylinder system 1 and the liquid cylinder system 2 establish an interconnected relationship, achieving mutual communication. The powder cylinder system 1 includes a powder cylinder 14, a powder piston 10, and a cap. The powder piston 10 and the cap form a sealed cavity inside the powder cylinder 14. The liquid medicine cylinder system 2 includes a liquid medicine cylinder 33, a liquid medicine piston 11, and a cap. The liquid medicine piston 11 and the cap seal the inside of the liquid medicine cylinder 33, forming a closed cavity. The powder cylinder 14 is used to hold powder, and the liquid medicine cylinder 33 is used to hold liquid medicine. The powder cylinder 14, the liquid medicine cylinder 33, and the mixing valve 3 are used to prepare for mixing the powder and the liquid medicine. The interconnection of the powder cylinder 14, the mixing valve 3, and the liquid medicine cylinder 33 enables high-viscosity mixing of the powder and the liquid medicine.

[0064] Specifically, the right end of the powder cylinder 14 is connected to the mixing valve 3. The mixing valve 3 includes a mixing hole 26 and a flow cut-off plate 27. In its normal state, the flow cut-off plate 27 blocks the mixing hole 26, thus cutting off the flow in the mixing hole 26. The cap is removed from the right end of the powder cylinder 14, and the powder cylinder 14 enters the mixing hole 26. The right end of the powder cylinder 14 contacts the flow cut-off plate 27 to achieve a seal. The powder cylinder system 1 is equipped with a left electric cylinder 6, which is connected to the powder piston 10. The left electric cylinder 6 drives the powder piston 10, and the powder piston 10 slides inside the powder cylinder 14, which can realize the expansion and contraction of the internal space of the powder cylinder 14. After the powder is put in, the powder piston 10 compresses the powder cylinder 14 under the drive of the left electric cylinder 6 and maintains it.

[0065] Specifically, the left end of the liquid medicine cylinder 33 is connected to the mixing valve 3. The cap of the left end of the liquid medicine cylinder 33 is removed, and the far end of the liquid medicine cylinder 33 is connected to the throttling plate 27 inside the mixing valve 3. The liquid medicine piston 11 and the throttling plate 27 seal both ends of the liquid medicine cylinder 33. The liquid medicine cylinder 33 is equipped with a dosing plunger valve 5, through which liquid medicine is added. The right end of the liquid medicine cylinder 33 is equipped with a right electric cylinder 7, which is connected to the liquid medicine piston 11. After adding liquid medicine to the liquid medicine cylinder 33, the right electric cylinder 7 is activated to compress the liquid medicine cylinder 33 and maintain the pressure when a certain pressure is reached.

[0066] The mixing device also includes a control system, which is electrically connected to the left electric cylinder 6 and the right electric cylinder 7. By controlling the system to ensure that the pressure of both the powder cylinder 14 and the liquid cylinder 33 reaches a certain limit value, and while ensuring that the internal pressure of the left electric cylinder 6 and the right electric cylinder 7 is constant, the throttling plate 27 of the mixing valve 3 is opened, pushing the right electric cylinder 7 to synchronously retreat the left electric cylinder 6. The left electric cylinder 6 and the right electric cylinder 7 move synchronously to mix the liquid and powder.

[0067] like Figure 2 As shown, the powder cylinder system 1 also includes a left self-locking knob plunger and a powder device bracket 16. The left self-locking knob plunger 8 is fixed on the powder device bracket 16. The left self-locking knob plunger 8 and the powder device bracket 16 can be fixed by welding, threaded connection, integrated design or any other connection method. The left self-locking knob plunger 8 is provided with a through hole (not shown in the figure) for the left end of the powder piston 10 to pass through. The powder plunger is connected to the left electric cylinder 6 through the through hole of the left self-locking knob plunger 8.

[0068] Specifically, the left self-locking rotary plunger 8 also includes a left self-locking knob 12. The left self-locking knob 12 is normally inserted. The right end of the left self-locking rotary plunger 8 is connected to the powder cylinder 14. The left self-locking knob 12 fixes the left self-locking rotary plunger 8 to the powder cylinder 14. The left self-locking rotary plunger (8) has a knob inside for locking and releasing the powder cylinder (14) to ensure that the powder cylinder 14 and the left self-locking rotary plunger 8 are stably connected during operation, which is safe and reliable.

[0069] Specifically, pull up the left self-locking knob 12 until the left end of the powder cylinder 14 is disengaged from the control of the left self-locking knob 12. The left self-locking knob 12 rotates down 90°, so that the pulled state of the left self-locking knob 12 is maintained. The powder cylinder 14 can be disengaged from the control of the self-locking knob plunger (left). Control the left electric cylinder 6 to disengage the powder piston 10 from the powder cylinder 14, and remove the powder cylinder 14 to add powder.

[0070] The liquid cylinder system 2 also includes a right-side self-locking rotary plunger 9 and a liquid device bracket 19. The right-side self-locking rotary plunger 9 is fixed on the liquid device bracket 19. The right-side self-locking rotary plunger 9 and the powder device bracket 16 can be fixed by any connection method such as welding, threaded connection, integrated design, etc. The right-side self-locking rotary plunger 9 is provided with a through hole (not shown in the figure) for the right end of the liquid piston 11 to pass through. The liquid piston 11 is connected to the right-side electric cylinder 7 through the through hole of the right-side self-locking rotary plunger 9.

[0071] Specifically, the right self-locking rotary plunger 9 also includes a right self-locking knob 13. The right self-locking knob 13 is normally inserted. The left end of the right self-locking rotary plunger 9 is connected to the liquid cylinder 33. The right self-locking knob 13 fixes the right self-locking rotary plunger 9 to the liquid cylinder 33, ensuring a stable and reliable connection between the liquid cylinder 33 and the right self-locking rotary plunger 9 during operation.

[0072] Specifically, pull the right self-locking knob 13 upwards until the right end of the medicine cylinder 33 is disengaged from the control of the right self-locking knob 13. The right self-locking knob 13 rotates downwards by 90°, so that the pulled state of the right self-locking knob 13 is maintained. The medicine cylinder 33 can be disengaged from the control of the right self-locking knob plunger. Control the right electric cylinder 7 to disengage the medicine piston 11 from the medicine cylinder 33, and remove the medicine cylinder 33 to add medicine.

[0073] Specifically, the powder-liquid mixing device is equipped with a control unit, which is electrically connected to the left electric cylinder 6 and the right electric cylinder 7. The power source for both the left electric cylinder 6 and the right electric cylinder 7 is a servo motor. The transmission synchronization of the left electric cylinder 6 and the right electric cylinder 7 is achieved through commands from the control system.

[0074] like Figure 1 As shown, the left electric cylinder 6 includes a left electric cylinder cavity and a left electric cylinder piston rod. The left electric cylinder 6 is driven by a servo motor. External commands are transmitted to the left electric cylinder 6 through the electrical signals of the control system, so that it moves according to predetermined requirements.

[0075] Specifically, the left electric cylinder 6 is fixed on the powder device bracket 16. The powder device bracket 16 is provided with a fixing plate (not shown in the figure). The left electric cylinder 6 is fixed on the fixing plate. When the control system commands the left electric cylinder 6 to move through an electrical signal, the two fixing plates are fixed on the powder device bracket 16. At the same time, they fix the position of the left electric cylinder 6 when it moves and provide support for the left electric cylinder 6.

[0076] Specifically, the left electric cylinder cavity is fitted around the outer periphery of the piston of the left electric cylinder 6. The piston rod of the left electric cylinder can slide along the left electric cylinder cavity. The servo motor drives the piston rod of the left electric cylinder to push the powder piston 10, thus preparing for the mixing of powder and liquid medicine. After reaching a certain pressure, the left electric cylinder 6 stops working and the piston rod of the left electric cylinder is locked, thus maintaining the internal pressure of the powder cylinder 14.

[0077] Specifically, the left electric cylinder piston rod is connected to the powder cylinder 14 via the left connecting piece 34. The central axes of the left electric cylinder piston rod, the left connecting piece 34, and the powder cylinder 14 are all the same. The left connecting piece 34 is detachably connected between the left electric cylinder piston rod and the powder piston 10. To disassemble the powder cylinder 14, the left connecting piece 34 needs to be separated from the powder piston 10, thus separating the powder cylinder 14. When the powder cylinder 14 needs to be installed on the powder-liquid mixing device, it is connected to the powder piston 10 via the left connecting piece 34. At the same time, the powder piston 10 is fixed to the left self-locking knob plunger 8. After rotating the left self-locking knob 12 upward by 90°, the left self-locking knob 12 is released. The self-locking knob automatically locks the left self-locking knob plunger 8 and the powder cylinder 14. At this time, the left electric cylinder 6, the left self-locking knob plunger 8, and the powder cylinder 14 are connected together.

[0078] Specifically, the powder cylinder system 1 also includes a left dovetail guide plate 17. The middle part of the left dovetail guide plate 17 protrudes to form a guide rail shape. The powder device support 16 is provided with a guide groove that matches the guide rail of the left dovetail guide plate 17. The powder device support 16 can slide left and right along the left dovetail guide plate 17. The left dovetail guide plate 17 connects the powder device support 16 and the support plate respectively. The left and right movement of the powder device support 16 is controlled by the left handle 20. Before loading and unloading the powder cylinder 14, the left handle 20 needs to be released first so that the powder device support 16 can move left and right relative to the left dovetail guide plate 17 to prepare for the installation and disassembly of the powder cylinder 14.

[0079] The right electric cylinder 7 includes a right electric cylinder cavity and a right electric cylinder piston rod. The right electric cylinder 7 is driven by a servo motor. External commands are transmitted to the right electric cylinder 7 through the electrical signals of the control system, so that it moves according to predetermined requirements.

[0080] Specifically, the right electric cylinder 7 is fixed on the medicine liquid device bracket 19. The medicine liquid device bracket 19 is provided with a fixing plate (not shown in the figure). The right electric cylinder 7 is fixed on the fixing plate. When the control system commands the right electric cylinder 7 to move through an electrical signal, the two fixing plates are fixed on the medicine liquid device bracket 19. At the same time, they fix the position of the right electric cylinder 7 when it moves and provide support for the right electric cylinder 7.

[0081] Specifically, the right electric cylinder cavity is fitted around the outer periphery of the piston of the right electric cylinder 7. The piston rod of the right electric cylinder can slide along the right electric cylinder cavity. The servo motor drives the piston rod of the right electric cylinder to push the liquid piston 11, thus preparing for the mixing of powder and liquid. After reaching a certain pressure, the right electric cylinder 7 stops working and the piston rod of the right electric cylinder is locked, thus maintaining the internal pressure of the liquid cylinder 33.

[0082] Specifically, the liquid cylinder system 2 also includes a right-side connector 35. The right-side electric cylinder piston rod is connected to the liquid cylinder 33 through the right-side connector 35. The central axes of the right-side electric cylinder piston rod, the right-side connector 35, and the liquid cylinder 33 are all on the same central axis. The right-side connector 35 is detachably connected between the right-side electric cylinder piston rod and the liquid piston 11. To disassemble the liquid cylinder 33, the right-side connector 35 needs to be separated from the liquid piston 11, thus separating the liquid cylinder 33. When the liquid cylinder 33 needs to be installed on the powder-liquid mixing device, it is connected to the liquid piston 11 through the right-side connector 35. At the same time, the liquid piston 11 is fixed to the right-side self-locking knob plunger 9. After rotating the right-side self-locking knob 13 upward by 90°, the right-side self-locking knob 13 is released. The right-side self-locking knob 13 automatically locks the right-side self-locking knob plunger 9 and the liquid cylinder 33. At this time, the right-side electric cylinder 7, the right-side self-locking knob plunger 9, and the liquid cylinder 33 are connected together.

[0083] Specifically, the liquid cylinder system 2 also includes a right dovetail guide plate 18. The middle part of the right dovetail guide plate 18 protrudes to form a guide rail shape. The bottom of the liquid device bracket 19 is provided with a guide groove that matches the guide rail of the right dovetail guide plate 18. The liquid device bracket 19 can slide left and right along the right dovetail guide plate 18. The right dovetail guide plate 18 connects the liquid device bracket 19 and the support plate respectively. The left and right movement of the liquid device bracket 19 is controlled by the right handle 21. Before loading and unloading the liquid cylinder 33, the right handle 21 needs to be released first so that the liquid device bracket 19 can move left and right relative to the right dovetail guide plate 18 to prepare for the installation and disassembly of the liquid cylinder 33.

[0084] like Figure 2 and 3 As shown, the right end of the powder cylinder 14 and the left end of the liquid medicine cylinder 33 are both provided with fine discharge ports. The fine discharge ports of the powder cylinder 14 and the fine discharge ports of the liquid medicine cylinder 33 are connected to achieve mixing of powder and medicine. The mixing valve 3 includes a flow-stopping handle 28, a mixing hole 26 and a flow-stopping plate 27. The two fine discharge ports are connected through the mixing hole 26 to achieve communication.

[0085] Specifically, before loading the powder, the narrow outlet of the powder cylinder 14 is sealed with a cap. After the required powder is placed inside the powder cylinder 14, the left handle 20 is opened to move to the left. At the same time, the powder device support 16 also moves to the left, and the powder device support 16 drives the left electric cylinder 6 to move to the left. The connecting block (left) separates from the powder piston 10, placing the powder piston 10 inside the powder cylinder 14 for pre-compression, while preventing the powder from tipping over and spilling. The left self-locking knob 12 of the left self-locking rotary plunger 8 is pulled upward and rotated 90° clockwise to position it in the desired position. With the cap removed from the powder cylinder 14, place the fine discharge port on the mixing hole 26 of the mixing valve 3. Simultaneously, press the flow cutter 27 to block the fine discharge port, preparing for the left electric cylinder 6 to press. The left end of the powder cylinder 14 contacts the left self-locking knob plunger 8. Rotate the left self-locking knob 12 counterclockwise by 90°. The left self-locking knob 12 returns to its original position, fixing the powder cylinder 14 and the left self-locking knob plunger 8. The left electric cylinder 6 drives the powder piston 10 to pressurize the powder cylinder 14. After reaching a certain pressure, maintain the pressure.

[0086] Specifically, the powder-liquid mixing device is also equipped with a vacuum machine 4, which includes a vacuum tube 25; the powder cylinder 14 is also equipped with a replenishment port 15. Before the left electric cylinder 6 pressurizes the powder cylinder 14, the vacuum tube 25 is connected to the powder cylinder 14 through the reversing valve body 3. While the vacuum machine 4 is drawing a vacuum into the powder cylinder 14 through the vacuum tube 25, the left electric cylinder 6 is started to press the powder cylinder 14; a filter element is provided at the far end of the vacuum tube 25. During the vacuuming process, the filter element effectively prevents the powder from being drawn out, effectively ensuring the accuracy of the powder weight each time the equipment is run; the powder cylinder 14 is also equipped with a replenishment port 15 to replenish the drawn-out powder.

[0087] Specifically, the liquid cylinder 33 is equipped with a dosing plunger valve 5. Before loading the liquid, the right handle 21 is opened to move it to the right, and the liquid device support 19 also moves to the right. Simultaneously, the liquid device support 19 drives the right electric cylinder 7 to move to the right, separating the connecting block (right) from the liquid piston 11. The liquid piston 11 is placed inside the liquid cylinder 33. The right self-locking knob 13 of the right self-locking rotary plunger 9 is pulled upwards and rotated 90° clockwise to release it. The fine outlet end of the liquid cylinder 33 is placed on the mixing hole 26 of the mixing valve 3, connecting with the flow cut-off plate 27, preparing for the right electric cylinder 7 to press. The left end of body 33 contacts the right self-locking knob plunger 9. Rotate the right self-locking knob 13 counterclockwise by 90°. The right self-locking knob 13 returns to its original position. Fix the medicine cylinder 33 and the right self-locking knob plunger 9 by turning the knob. Add the medicine into the medicine cylinder 33 through the dosing plunger valve 5. The medicine cylinder 33, the medicine piston 11 and the cutoff plate 27 form a seal. Dosing can only be done through the dosing plunger valve 5. After the dosing is completed, connect the vacuum tube 25 to the dosing plunger valve 5 to realize the vacuuming of the medicine cylinder 33. At the same time, the right electric cylinder 7 drives the medicine piston 11 to pressurize the medicine cylinder 33. After reaching a certain pressure, maintain the pressure.

[0088] like Figure 4 and Figure 9 and Figure 10 As shown, in some embodiments, the powder cylinder 14 is provided with a scale, and the powder cylinder is a transparent structure that can be observed. When filling the powder, a certain amount of powder is filled into the powder cylinder 14, and the filling amount can also be observed through the scale transparent structure. After the powder is filled, the powder cylinder 14 is placed in a fixed position. At this time, the entire powder mixing device is weighed again after removing the weight of the device by an external weighing device, so as to realize the weighing of the powder before vacuuming.

[0089] Specifically, the powder cylinder system 1 is also equipped with a powder replenisher 23 and a precision balance 22. The powder replenisher 23 has a scale line. After the replenished powder is filled into the powder replenisher 23, the powder replenisher 23 is shaken to make the powder spacing even. The scale line is observed to make a rough assessment. The powder replenisher 23 is then placed on the precision balance 22 for weighing. After weighing, the powder that meets the weighing standard is added into the powder cylinder 14 through the powder replenisher 23. The cap of the replenishment port 15 is opened, and the powder replenisher 23 fills the powder cylinder 14 with powder through the replenishment port 15. After the addition is completed, the vacuum tube 25 is connected to the replenishment port 15. The vacuum tube 25 is equipped with a replenishment filter element 31. The replenishment filter element 31 can effectively prevent powder from entering the vacuum tube 25, effectively ensuring the dosage of powder in the powder cylinder 14. The replenishment filter element 31 is placed inside the powder cylinder 14, and a vacuum is drawn.

[0090] like Figure 1 As shown, the liquid medicine cylinder system 2 includes a dosing plunger valve 5. The liquid medicine cylinder 33 is placed on the powder-liquid mixing device. After the liquid medicine is added through the dosing plunger valve 5, the electric cylinder 7 on the right side applies pressure to prepare for the mixing of powder and liquid medicine.

[0091] like Figure 11 As shown, in another structural form of the mixing valve 3 of the present invention, the mixing orifice 26 is stepped. The left end of the mixing orifice 26 is connected to the fine outlet of the powder cylinder 14, and the right end of the mixing orifice 26 is connected to the fine outlet of the liquid cylinder 33. The components of the Laval nozzle type are realized through the powder cylinder 14, the fine outlet of the powder cylinder 14, the mixing orifice 26, the fine outlet of the liquid cylinder 33, and the liquid cylinder 33. When the liquid cylinder 33 has been evacuated, the flow-stopping handle 28 is pulled upward, and the flow-stopping handle 28 drives the flow-stopping plate 27 to move upward, thus opening the flow. Through the two ends of the mixing hole 26, the control system controls the left electric cylinder 6 and the right electric cylinder 7 to move under the same pressure. The right electric cylinder 7 moves to the left, pushing the liquid medicine through the AC port of the mixing valve 3 to be compressed. The cross-section becomes smaller and the flow rate increases. After the liquid medicine reaches the powder cylinder 14, the cross-section increases rapidly. However, at this time, the principle of small flow rate at large cross-section is not followed. The high-speed fluid formed by the liquid medicine through the mixing hole 26 directly disperses the powder along the powder cylinder 14 corresponding to the center direction of the mixing hole 26, and quickly mixes the powder and the liquid medicine. The mixing speed of the powder and the liquid medicine is greatly accelerated.

[0092] like Figure 8 As shown, the mixing valve 3 opens and closes the mixing hole 26 channel by lifting or pressing the throttling handle 28, thereby driving the throttling plate 27.

[0093] like Figure 1 The powder cylinder 14 has a funnel-shaped contraction tube at its right end, with a fine outlet at its right end. The liquid cylinder 33 has a funnel-shaped contraction tube at its left end, with a fine outlet at its left end as well. The diameters of both the powder cylinder 14 and the liquid cylinder 33 are 6 mm, and the diameter of the fine outlet is 3 mm. Since the front and rear ends of the channel consist of a contraction tube and an expansion tube, it can be assumed that the mixing valve 3, the powder cylinder 14, and the liquid cylinder 33 form two conical structures. Therefore, the fluid flow conforms to the working principle of the Laval nozzle.

[0094] like Figure 1 and Figure 2As shown, to add powder: Loosen and pull the left handle 20, move the entire powder mixing device (left electric cylinder 6, powder cylinder 14, powder device bracket 16) to the left along the left dovetail guide plate 17, so that the right end of the powder cylinder 14's fine discharge port is away from the inner interface mixing hole 26 of the mixing valve 3's valve seat. Then pull the left self-locking knob 12 of the left self-locking knob plunger 8 upwards and rotate it 90 degrees clockwise or counterclockwise. At this time, the front end of the left knob that was originally locking the powder cylinder 14 retracts, so the powder cylinder 14 can be pulled out from the powder piston 10. Then cover the right end of the fine discharge port with the cap, and pour the loose powder into the powder cylinder 14 in a measured amount until it reaches 4 / 5 of the position. Next, push the powder piston 10 into the powder cylinder 14 along the flared guide at the rear end of the powder cylinder 14. Then pull the left self-locking knob 12 upwards and rotate it 90 degrees to release the lock. The front end of the knob will extend out and relock the powder cylinder 14. Then pull the left handle 20 and move the powder mixing device (left electric cylinder 6, powder cylinder 14, powder device bracket 16) to the right along the left dovetail guide plate 17, so that the fine discharge port at the right end of the powder cylinder 14 enters and closely adheres to the inner concave interface mixing hole 26 of the valve seat, preparing for pushing the mixing and vacuuming. The powder to be replenished is weighed by the precision balance 22 and added to the powder cylinder 14 through the replenishment port 15 using the powder replenisher 23. After adding, cover the replenishment port 15 with the cap. Then press down the throttling plate 27 of the mixing valve 3 to block the fine discharge port of the powder cylinder 14, connect the vacuum tube 25 to the replenishment port 15, and at the same time, slowly push the left electric cylinder 6 to the right, start the vacuum machine 4, and slowly remove the air squeezed out of the powder. After the vacuum machine 4 reaches the set value for vacuuming, the vacuum machine 4 stops working, the left electric cylinder 6 stops extruding, and the vacuum machine 4 is equipped with a sealing device to seal the vacuum tube 25. One end of the vacuum tube 25 is connected to the powder cylinder 14, and the other end is sealed. At this time, the vacuum machine 4 is turned off.

[0095] Specifically, adding the liquid medicine: Since the liquid medicine is a liquid, it cannot be added in the same way as powder. Therefore, adding the liquid medicine is achieved through a specially designed dosing plunger valve 5. The liquid medicine is added through the dosing plunger valve 5, and the dosing plunger valve 5 is closed after the liquid medicine is added.

[0096] Specifically, the powder and liquid are mixed as follows: When the powder in the powder cylinder 14 is compressed by the left-side electric cylinder 6 pushing the powder piston 10, the air inside the powder is squeezed out and removed by the vacuum machine 4. After the process requirements are met, the left-side electric cylinder 6 stops compressing, the vacuum machine 4 is turned off, the flow-stopping handle 28 is pulled up, and the flow-stopping plate 27 moves upward under the action of the flow-stopping handle 28. The thickness of the flow-stopping plate 27 is 0.1~1mm. Then the mixing begins. First, the liquid piston 11 is pushed to the left. Since the fine outlet has a diameter of 3mm, and both ends of the contraction tube (funnel-shaped structure at the left end of the liquid inlet) and the expansion tube (funnel-shaped structure at the rear end of the powder inlet) have a diameter of 6mm, and since the front and rear ends of the channel are a contraction tube and an expansion tube, it can be considered that the mixing valve 3, the powder cylinder 14 and the liquid cylinder 33 form two conical structures. Therefore, the fluid flow conforms to the working principle of the Laval nozzle. When the liquid medicine first enters the contraction tube (the funnel-shaped structure at the right end of the liquid medicine inlet), the fluid movement follows the principle that "the flow velocity is higher where the cross-section is smaller and lower where the cross-section is larger" during this stage, thus the fluid continuously accelerates. By the time it reaches the mixing orifice 26, the flow velocity is already relatively high. When it reaches the expansion tube (the funnel-shaped structure at the rear end of the powder inlet) through the mixing valve 3, the accelerated fluid no longer follows the principle of "higher flow velocity at smaller cross-section and lower flow velocity at larger cross-section," but rather the opposite: the larger the cross-section, the faster the flow velocity. In this way, the liquid medicine rushes into the powder cylinder 14 at a high speed, and the powder is instantly and uniformly wetted and rapidly dispersed upon first contact with the liquid.

[0097] During the mixing process, both the powder cylinder system 1 and the liquid cylinder system 2 are equipped with push-pull force sensors (not labeled). Therefore, the cylinders switch operating modes based on the sensed thrust during the pushing process. When the left-side cylinder 6 of the powder cylinder system 1 senses excessive thrust affecting mixing, it immediately stops operating, and the right-side cylinder 7 of the liquid cylinder system 2 immediately starts operating, pushing the liquid piston 11 to begin mixing. When the right-side cylinder 7 of the liquid cylinder system 2 senses excessive thrust affecting mixing, it immediately stops operating, and the left-side cylinder 6 of the powder mixing device immediately starts operating, pushing the powder piston 10 to begin mixing. This cycle repeats until the product meets the process requirements, with a final viscosity of 2 million centipoise.

[0098] Specifically, for finished product discharge: loosen and pull the left handle 20, and move the entire powder cylinder system 1 (left electric cylinder 6, powder cylinder 14, powder device bracket 16) to the left along the dovetail guide plate, so that the right end of the fine discharge port of the powder cylinder 14 is a distance away from the inner concave interface mixing hole 26 of the mixing valve 3 valve seat.

[0099] Loosen and pull the right handle 21, and move the entire liquid cylinder system 2 (right electric cylinder 7, liquid cylinder 33, liquid device bracket 19) to the right along the dovetail guide plate, so that the left end of the liquid cylinder 33 is a distance away from the inner concave interface mixing hole 26 of the mixing valve 3 seat.

[0100] If the finished product is inside the powder cylinder 14 on the left, as long as the left electric cylinder 6 on the left is turned on and pushes the powder piston 10, the finished product can be discharged from the fine discharge port at the right end of the powder cylinder 14.

[0101] If the finished product is inside the liquid cylinder 33 on the right side, as long as the right electric cylinder 7 on the right side is turned on and pushes the liquid piston 11, the finished product can start to be discharged from the fine discharge port at the left end of the liquid cylinder 33.

[0102] The above embodiments are merely preferred embodiments of the present invention and should not be construed as limiting the scope of protection of the present invention. Any non-substantial changes and substitutions made by those skilled in the art based on the present invention shall fall within the scope of protection claimed by the present invention.

Claims

1. A powder-liquid mixing device, comprising: The mixed valve (3), and the powder cylinder system (1) and the liquid cylinder system (2) and the support plate arranged on the mixed valve (3), characterized in that the powder cylinder system (1) comprises a powder cylinder (14) and a powder piston (10) slidingly fitted on the powder cylinder (14), the right end of the powder cylinder (14) being connected with the mixed valve (3); the liquid cylinder system (2) comprises a liquid cylinder (33) and a liquid piston (11) slidingly fitted on the liquid cylinder (33), the left end of the liquid cylinder (33) being connected with the mixed valve (3); the powder cylinder (14) and the liquid cylinder (33) are both horizontally arranged on the support plate, the powder cylinder (14) and the liquid cylinder (33) are communicated through the mixed valve (3) to perform high-viscosity mixing of powder and liquid. The mixed valve (3) comprises: a mixed hole (26), the mixed hole (26), the powder cylinder (14) and the liquid cylinder (33) being located on the same central axis, the powder cylinder (14) and the liquid cylinder (33) being connected through the mixed hole (26); a cut-off piece (27), dividing the mixed hole into two sections, the cut-off piece (27) being capable of slidingly disconnecting or connecting the mixed hole (26); a cut-off handle (28) connected with the cut-off piece (27), the cut-off handle (28) controlling the movement of the cut-off piece (27).

2. The powder-liquid mixing device according to claim 1, wherein The powder cylinder system (1) comprises: a left electric cylinder (6) connected with the powder piston (10), the left electric cylinder (6) controlling the left and right sliding movement of the powder piston (10) in the powder cylinder (14); a powder device support (16) comprising a left handle (20), the left electric cylinder (6) being placed on the powder device support (16); a left dovetail guide plate (17), the powder device support (16) being connected with the support plate through the left dovetail guide plate (17), the left handle (20) controlling the movement distance of the powder device support (16) on the left dovetail guide plate (17).

3. The powder-liquid mixing device according to claim 2, wherein The powder cylinder system (1) further comprises a left self-locking rotary knob plunger (8) fixedly arranged on the powder device support (16), the left end of the left self-locking rotary knob plunger (8) being connected with the left end of the powder cylinder (14); the left end of the powder piston (10) passes through the left self-locking rotary knob plunger (8) to be connected with the left electric cylinder (6), the left electric cylinder (6) being coaxially arranged with the powder piston (10); the left self-locking rotary knob plunger (8) is internally provided with a left knob for locking and unlocking the powder cylinder (14).

4. The powder-liquid mixing device according to claim 3, wherein The left self-locking rotary knob plunger (8) comprises a left self-locking rotary knob (12) for controlling the locking and unlocking of the left self-locking rotary knob plunger (8) and the powder cylinder (14).

5. The powder-liquid mixing device according to claim 2, wherein The left electric cylinder (6) comprises: A left side electric cylinder cavity provides power for the powder piston (10); A left side electric cylinder piston rod is located in the left side electric cylinder cavity, the right end of the left side electric cylinder piston rod is connected with the powder piston (10), and the left side electric cylinder piston rod is coaxially arranged with the powder barrel body (14).

6. The powder-liquid mixing device according to claim 5, wherein The liquid medicine barrel system (2) further comprises a left side connecting piece (34), the left side connecting piece (34) is connected with the left side electric cylinder piston rod and the powder piston (10) respectively, and the left side connecting piece (34) is coaxially arranged with the powder barrel body (14).

7. The powder-liquid mixing device according to claim 1, wherein The liquid medicine barrel system (2) comprises: A right side electric cylinder (7) is connected with the liquid medicine piston (11), and the right side electric cylinder (7) controls the liquid medicine piston (11) to slide left and right in the liquid medicine barrel (33); A liquid medicine device support (19) comprises a right side handle (21), and the right side electric cylinder (7) is placed on the liquid medicine device support (19); A right side dovetail guide plate (18) is connected with the support plate through the right side dovetail guide plate (18), and the right side handle (21) controls the moving distance of the liquid medicine device support (19) on the right side dovetail guide plate (18).

8. The powder-liquid mixing device according to claim 7, wherein The liquid medicine barrel system (2) further comprises a right side self-locking type rotary knob plunger (9), the right side self-locking type rotary knob plunger (9) is fixedly arranged on the liquid medicine device support (19), and the right side self-locking type rotary knob plunger (9) is connected with the liquid medicine barrel (33); the right side electric cylinder (7) passes through the right side self-locking type rotary knob plunger (9) and is connected with the liquid medicine piston (11), and the right side electric cylinder (7) is coaxially arranged with the liquid medicine piston (11); the right side self-locking type rotary plunger (9) is internally provided with a right knob for locking and unlocking the liquid medicine barrel (33).

9. The powder-liquid mixing device according to claim 8, wherein The right side self-locking type rotary knob plunger (9) comprises a right side self-locking rotary knob (13), which controls the locking and unlocking of the right side self-locking type rotary knob plunger (9) and the liquid medicine barrel (33).

10. The powder-liquid mixing device according to claim 7, wherein The right side electric cylinder (7) comprises: A right side electric cylinder cavity provides power for the liquid medicine piston (11); A right side electric cylinder piston rod is located in the right side electric cylinder cavity, the right end of the right side electric cylinder piston rod is connected with the liquid medicine piston (11), and the right side electric cylinder piston rod is coaxially arranged with the liquid medicine barrel (33).

11. The powder-liquid mixing device according to claim 10, wherein The liquid medicine barrel system (2) further comprises a right side connecting piece (35), the right side connecting piece (35) is connected with the right side electric cylinder piston rod and the liquid medicine piston (11) respectively, and the right side connecting piece (35) is coaxially arranged with the liquid medicine barrel (33).

12. The powder-liquid mixing device according to claim 1, wherein The powder barrel system (1) further comprises: A supplement port (15) is located on the powder barrel body (14), and the powder barrel body (14) is sealed by a cap; A powder supplementer (23) is used in cooperation with the powder cylinder (14) as an external device, including a scale line, and the powder is filled into the powder supplementer (23) to prepare for the powder supplement; A precision balance (22) is used in cooperation with the powder supplementer as an external device to weigh the weight of the powder in the powder supplementer (23).

13. The powder-liquid mixing device according to claim 1, wherein The medicine cylinder system (2) further comprises a medicine adding plunger valve (5) fixed on the medicine cylinder (33) and communicating with the inner cavity of the medicine cylinder (33); the medicine enters the medicine cylinder (33) through the medicine adding plunger valve (5).

14. The powder-liquid mixing device according to any one of claims 12 and 13, wherein The powder-liquid mixing device further comprises a vacuum machine (4) comprising a vacuum pipe (25) connected with the powder cylinder (14) to perform vacuumization on the powder cylinder (14); the vacuum pipe (25) is connected with the medicine cylinder (33), and the vacuum pipe (25) performs vacuumization on the medicine cylinder (33).

15. The powder-liquid mixing device according to claim 1, wherein The powder cylinder (14) and the medicine cylinder (33) are both transparent structures and can be used to observe the fusion degree of the powder and the medicine.

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