A liquid-based thin-layer cell preparation machine

By integrating the slide centrifugation, drying, slide supply, transportation and sample liquid transportation mechanisms, the slide production is automated, solving the problems of the existing slide production process being cumbersome and inefficient, improving production efficiency and reducing the waste rate.

CN116086910BActive Publication Date: 2025-10-24SUZHOU TURING MICROBIAL TECH CO LTD
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Patent Information

Application Number
CN202211737008.7
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2022-12-30
Publication Date
2025-10-24
Estimated Expiration
2042-12-30

AI Technical Summary

Technical Problem

The existing slide production process is cumbersome, inefficient, has a high waste rate, and manual operation is time-consuming and labor-intensive.

Method used

The slide centrifugation mechanism, slide drying mechanism, slide feeding mechanism, slide conveying mechanism, test tube conveying mechanism, and sample liquid conveying mechanism are integrated to automate slide production. The automated operation is achieved through components such as robotic arms and negative pressure vacuum pumps.

Benefits of technology

It has automated the production of glass slides, saving manpower, improving production efficiency, and reducing the scrap rate.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application provides a liquid-based thin-layer cell preparation machine, which comprises a rack, a base arranged at the bottom of the rack, a slide centrifugation mechanism arranged on the base and comprising a centrifuge rack, a centrifuge driving device arranged on the centrifuge rack and a slide box connected with the centrifuge driving device, a slide drying mechanism comprising a drying machine and a drying groove plate arranged above the drying machine, a slide supply mechanism comprising a slide storage device and a slide lifting device connected with the slide storage device, a slide conveying mechanism arranged above the slide supply mechanism and used for extracting slides from the slide supply mechanism and transporting the slides into the slide box and the drying groove plate, a test tube conveying mechanism arranged on the base and used for extracting test tubes and opening the test tubes, and a sample liquid conveying mechanism arranged on the base and used for extracting sample liquid in the test tubes and dropping the sample liquid on the slides transported into the slide box. The application realizes the dropping of sample liquid on the slides, centrifugation and drying of the sample liquid, and improves the efficiency.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, in particular to a liquid-based thin-layer cell preparation machine. BACKGROUND

[0002] A slide is a glass or quartz sheet used to carry a sample for observation with a microscope. At present, when a slide carrying a sample is prepared, a sample liquid is extracted from a test tube by using a pipette tip by hand, and the sample liquid is dropped on the slide, then a cotton swab is used to evenly smear the sample liquid on the slide, and a drying device is used to dry the slide. The above process is complicated, and the waste rate is high, which reduces the generation efficiency. SUMMARY

[0003] Therefore, the present application provides a liquid-based thin-layer cell preparation machine to solve the problem of low efficiency in the preparation of the existing slide.

[0004] To solve the above technical problems, the present application adopts the following technical solutions:

[0005] According to the liquid-based thin-layer cell preparation machine of the embodiment of the present application, the machine rack includes a base and two groups of base plates symmetrically arranged on the base; the slide centrifugal mechanism is arranged on the base and includes a centrifuge rack, a centrifugal driving device arranged on the centrifuge rack, and a slide box connected with the centrifugal driving device; the slide drying mechanism is arranged on the base and includes a drying machine and a drying groove plate arranged above the drying machine; the slide supply mechanism is arranged on the base and includes a slide storage device and a slide lifting device connected with the slide storage device; the slide conveying mechanism is arranged above the slide supply mechanism and is used to extract the slide from the slide supply mechanism and sequentially transport the slide to the slide box and the drying groove plate; the test tube conveying mechanism is arranged on the base and is used to extract the test tube and open the test tube cap; and the sample liquid conveying mechanism is arranged on the base and is used to extract the sample liquid in the test tube by using a pipette tip and drop the sample liquid on the slide transported into the slide box.

[0006] The liquid-based thin-layer cell preparation machine of the present application stores the slide through the slide supply mechanism and lifts the slide upward through the slide lifting device. Then the slide is extracted into the slide box of the slide centrifugal mechanism through the slide conveying mechanism. At the same time, the test tube conveying mechanism can extract the test tube and open the test tube cap. After the slide reaches the slide box, the sample liquid conveying mechanism can extract the sample liquid in the test tube by using a pipette tip and drop the sample liquid on the slide transported into the slide box. Then the slide centrifugal mechanism can be rotated to centrifuge the sample liquid.

[0007] After centrifugation is completed, the slide conveying mechanism conveys the slide to the slide drying mechanism for drying. The present application 5 integrates various mechanisms required for slide making, realizes automation of slide making, effectively saves manpower, and improves production efficiency.

[0008] In an embodiment of the present application, a slide lifting outlet is formed above the slide storage device.

[0009] In an embodiment of the present application, the slide conveying mechanism comprises:

[0010] The first moving module comprises a first horizontal sliding rail and a first vertical sliding rail connected to the first horizontal sliding rail through a first horizontal sliding block, and the first horizontal sliding rail is connected to the rack;

[0011] The suction cup grabbing module is connected to the first vertical sliding rail through a first vertical sliding block, and the suction cup grabbing module comprises a multi-way suction pipe and a suction cup connected to the multi-way suction pipe;

[0012] The negative pressure vacuum pump is connected to the multi-way suction pipe and is used to provide negative pressure to the suction cup.

[0013] In an embodiment of the present application, the liquid-based thin-layer cell preparation machine further comprises: a sample holder which is detachably connected to the base 5, and the sample holder is used to store test tubes.

[0014] In an embodiment of the present application, the base is formed with a moving sliding rail at one end away from the base, the base is provided with a test tube fixing socket, and the test tube conveying mechanism comprises:

[0015] The second moving module comprises a second horizontal sliding rail which is slidingly connected to the moving sliding rail, and a second vertical sliding rail which is connected to the second horizontal sliding rail through a second horizontal sliding block;

[0016] The cap opening device is connected to the second vertical sliding rail through a second vertical sliding block, and comprises a cap opening motor and a rotating clamp jaw connected to the cap opening motor, the rotating clamp jaw is used to clamp a test tube in the sample holder and extract it into the test tube fixing socket for fixation and cap opening.

[0017] In an embodiment of the present application, the liquid-based thin-layer cell preparation machine further comprises:

[0018] The pipette tip placing seat is formed with a hollow accommodating opening;

[0019] The pipette tip support is used to be installed in the accommodating opening, and the pipette tip support is formed with a plurality of plate holes for accommodating pipette tips.

[0020] In an embodiment of the present application, the sample liquid conveying mechanism comprises:

[0021] The third moving module comprises a third horizontal sliding rail connected with a moving sliding rail on the base plate away from the side of the pipette tip placing seat, an extension arm connected with the third horizontal sliding rail through a third horizontal sliding block, and a third vertical sliding rail connected with the extension arm;

[0022] The pipette pump is connected with the third vertical sliding rail through a third vertical sliding block, used for grabbing the pipette tip in the pipette tip holder and controlling the pipette tip to drop the sample liquid on the slide when reaching above the slide box.

[0023] In an embodiment of the present application, the liquid-based thin-layer cell preparation machine further comprises:

[0024] The recovery box is arranged on the base and used for recovering the pipette tip. The recovery box is provided with a placing tube used for storing a test tube cover.

[0025] In an embodiment of the present application, the base plate near the side of the pipette tip holder is provided with a loading and unloading opening. The liquid-based thin-layer cell preparation machine further comprises:

[0026] The cable containing rack is arranged on the base plate away from the side of the pipette tip holder. The cable containing rack is provided with a cable containing cavity.

[0027] The shell is arranged on the cable containing rack and the rack. The shell is respectively provided with an upper flip cover in communication with the cable containing cavity and a lower flip cover in communication with the loading and unloading opening.

[0028] In an embodiment of the present application, the shell is provided with a slide output opening near the side of the slide feeding mechanism. The liquid-based thin-layer cell preparation machine further comprises:

[0029] The output belt line is arranged in the slide output opening and extends away from the shell, used for outputting the slide outward.

[0030] The above technical scheme of the present application has at least one of the following beneficial effects:

[0031] The liquid-based thin-layer cell preparation machine integrates the slide centrifuging mechanism, the slide drying mechanism, the slide feeding mechanism, the slide conveying mechanism, the test tube conveying mechanism and the sample liquid conveying mechanism, realizes the automation of slide production, effectively saves manpower and improves production efficiency. BRIEF DESCRIPTION OF DRAWINGS

[0032] Figure 1 It is a left view of the liquid-based thin-layer cell preparation machine of the embodiment of the present application;

[0033] Figure 2 It is a front view of the liquid-based thin-layer cell preparation machine of the embodiment of the present application;

[0034] Figure 3 It is a right view of the liquid-based thin-layer cell preparation machine of the embodiment of the present application;

[0035] Figure 4 A top view of a liquid-based thin-layer cell preparation machine according to an embodiment of the present application;

[0036] Figure 5 A structural schematic diagram of a liquid-based thin-layer cell preparation machine according to an embodiment of the present application after loading of a shell;

[0037] Figure 6 Another structural schematic diagram of a liquid-based thin-layer cell preparation machine according to an embodiment of the present application after loading of a shell;

[0038] Reference signs: 110, base; 111, test tube fixing socket; 120, base plate; 121, moving slide rail; 200, slide centrifugation mechanism; 210, slide box; 220, centrifuge frame; 230, centrifuge driving device; 300, slide drying mechanism; 310, drying groove plate; 320, drying machine; 410, slide storage device; 411, slide lifting outlet; 511, first horizontal slide rail; 512, first vertical slide rail; 521, multi-way suction pipe; 522, suction disc; 530, negative pressure vacuum pump; 600, sample frame; 611, second horizontal slide rail; 612, second vertical slide rail; 613, cover opening motor; 614, rotating clamping jaw; 700, pipette tip placing seat; 701, pipette tip support; 810, extending arm; 820, third vertical slide rail; 830, pipette pump; 910, recovery box; 911, placing tube; 920, cable containing frame; 930, shell; 931, upper flip cover; 932, lower flip cover; 933, touch screen; 934, observation window; 940, output belt line. DETAILED DESCRIPTION

[0039] In order to make the objectives, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions of the embodiments of the present application will be described below in connection with the drawings of the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments of the present application. Based on the described embodiments of the present application, all other embodiments obtained by those of ordinary skill in the art belong to the scope of protection of the present application.

[0040] Unless otherwise defined, the technical or scientific terms used in the present invention shall have the usual meanings understood by persons of ordinary skill in the field to which the present invention belongs. The words "first", "second" and similar terms used in the present invention do not indicate any order, quantity or importance, but are only used to distinguish different components. Similarly, words such as "one" or "a" do not indicate a quantity limitation, but rather indicate the existence of at least one. Words such as "connected" or "connected" are not limited to physical or mechanical connections, but may include electrical connections, whether direct or indirect. "Up", "down", "left", "right" and the like are only used to indicate relative positional relationships. When the absolute position of the object being described changes, the relative positional relationship also changes accordingly.

[0041] In the existing slide production process, most of the steps are manual operations, which are time-consuming and labor-intensive, and have low production efficiency. To solve the above problems, the present application provides a liquid-based thin layer cell slide making machine.

[0042] First, a liquid-based thin layer cell slide preparation machine according to an embodiment of the present invention will be described in detail below with reference to the accompanying drawings.

[0043] like Figures 1-3 As shown, a liquid-based thin layer cell preparation machine according to an embodiment of the present invention includes: a frame, a glass slide centrifugal mechanism 200, a glass slide drying mechanism 300, a glass slide supply mechanism, a glass slide conveying mechanism, a test tube conveying mechanism, and a sample liquid conveying mechanism. The frame includes a base 110 and two sets of base plates 120 symmetrically arranged on the base 110; the glass slide centrifugal mechanism 200 is arranged on the base 110, including a centrifuge frame 220, a centrifugal drive device 230 arranged on the centrifuge frame 220, and a glass slide box 210 connected to the centrifugal drive device 230; the glass slide drying mechanism 300 is arranged on the base 110, including a dryer 320 and a drying tank plate 310 arranged above the dryer 320; the glass slide supply mechanism is arranged on the base 110, including a glass The slide storage device 410 and the slide lifting device connected to the slide storage device 410; the slide transport mechanism is arranged above the slide supply mechanism, which is used to extract slides from the slide supply mechanism and transport the slides to the slide box 210 and the drying tank plate 310 in sequence; the test tube transport mechanism is arranged on the base 110, which is used to extract test tubes and open the test tube covers; the sample liquid transport mechanism is arranged on the base 110, which is used to use a pipette tip to extract the sample liquid in the test tube and add the sample liquid to the slide transported to the slide box 210.

[0044] Specifically, in the process of making the slide, a plurality of slides can be first stored in the slide storage device 410 of the slide supply mechanism, and the slides are lifted upward by the slide lifting device in the slide storage device 410. Then the slides can be extracted into the slide box 210 of the slide centrifugation mechanism 200 by the slide conveying mechanism. At the same time, the test tube conveying mechanism can extract a single test tube and open the test tube cap above the test tube. After the slide enters the slide box 210, the sample liquid conveying mechanism can extract the pipette and use the pipette to extract the sample liquid in the test tube, and then drop the sample liquid to the slide transported into the slide box 210. After the sample liquid is dropped, the centrifugal drive device 230 starts and drives the slide box 210 to start rotating to centrifuge the sample liquid. After the centrifugation is completed, the slide conveying mechanism conveys the slide into the drying groove plate 310 on the slide drying mechanism 300, at which time the drying machine 320 can start to dry the slide. Thus, the various mechanisms required for slide making are integrated, the automation of the slide making process is realized, the manpower is effectively saved, and the production efficiency is improved.

[0045] As shown in Figure 2 In an embodiment of the present application, a slide lifting outlet 411 is formed above the slide storage device 410. Specifically, the slide lifting device arranged in the slide storage device 410 can lift the slide to the slide lifting outlet 411, at which time the slide conveying mechanism above the slide lifting outlet 411 can be lowered and the stored slide can be taken away. Thus, the slide supply process is realized, and manual arrangement of the slide one by one is not required, saving manpower.

[0046] As shown in Figure 2 In an embodiment of the present application, the slide conveying mechanism comprises a first moving module, a suction cup 522 grabbing module, and a suction cup 522 grabbing module. The first moving module comprises a first horizontal sliding rail 511 and a first vertical sliding rail 512 connected to the first horizontal sliding rail 511 through a first horizontal sliding block, and the first horizontal sliding rail 511 is connected to the rack; the suction cup 522 grabbing module is connected to the first vertical sliding rail 512 through a first vertical sliding block, and the suction cup 522 grabbing module comprises a multi-way suction tube 521 and a suction cup 522 connected to the multi-way suction tube 521; a negative pressure vacuum pump 530 is connected to the multi-way suction tube 521 for providing negative pressure to the suction cup 522.

[0047] Specifically, the first horizontal slide rail 511 in the first moving module and the first vertical slide rail 512 connected with the first horizontal slide rail 511 can control the horizontal position and the vertical position of the suction module through the sliding control of the suction disc 522. Meanwhile, the suction disc 522 of the suction module can be in contact with the slide from both sides through the double-pipe duct, thereby increasing the stability when the slide is grabbed. In addition, the flexible suction disc 522 at the end of the double-pipe duct can buffer the impact force when the slide is contacted, and increase the contact area with the slide, thereby avoiding damaging the slide and enhancing the suction force. The negative pressure vacuum pump 530 connected with the double-pipe duct has strong suction force, and can provide negative pressure to the suction disc 522. Thus, the slide can be stably grabbed and transported.

[0048] As shown in Figure 3 In one embodiment of the present application, the liquid-based thin-layer cell preparation machine further comprises a sample rack 600 detachably connected with the base 110, and the sample rack 600 is used for storing a plurality of test tubes. That is, the test tube conveying mechanism can extract the test tubes one by one from the sample rack 600 without manual intervention. Thus, the manpower is effectively saved.

[0049] As shown in Figure 2 and Figure 3 In one embodiment of the present application, the base 110 is formed with a moving slide rail 121 at one end away from the base 110, and the base 110 is provided with a test tube fixing socket 111. The test tube conveying mechanism comprises a second moving module and a cap opening device. The second moving module comprises a second horizontal slide rail 611 in sliding connection with the moving slide rail 121, and a second vertical slide rail 612 connected with the second horizontal slide rail 611 through a second horizontal slide block. The cap opening device is connected with the second vertical slide rail 612 through a second vertical slide block, and comprises a cap opening motor 613 and a rotating clamp jaw 614 connected with the cap opening motor 613. The rotating clamp jaw 614 is used for clamping the test tube in the sample rack 600 and extracting the test tube to the test tube fixing socket 111 for fixation and cap opening.

[0050] Specifically, the second horizontal slide rail 611 of the second moving module can move horizontally along the moving slide rail 121, and the second vertical slide rail 612 is connected with the second horizontal slide rail 611 through the second horizontal slide block and slides. The cap opening device is connected with the second vertical slide rail 612 through the second vertical slide block. Thus, the horizontal and vertical positions of the cap opening device can be controlled. When the test tube is extracted, the cap opening device can be lowered above the test tube rack, and the rotating clamp jaw 614 is used to clamp the test tube cap of the test tube. Then, the cap opening device moves upward and moves to the test tube fixing socket 111, and the test tube is inserted into the test tube fixing socket 111. At this time, the rotating clamp jaw 614 can be rotated to open the test tube cap of the test tube. Thus, the automation of test tube extraction and cap opening is realized, and the production efficiency is improved.

[0051] As shown in Figure 3As shown, in one embodiment of the present application, the liquid-based thin layer cell preparation machine further includes: a pipette tip placement seat 700 and a pipette tip support 701.

[0052] A hollow receiving opening is formed in the pipette tip placement base; a pipette tip holder 701 is mounted within the receiving opening and has a plurality of plate wells for receiving pipette tips. In other words, pipette tips can be stored in the wells of the pipette tip holder 701, and the sample liquid transfer mechanism can extract the pipette tips from the pipette tip holder 701 one by one, eliminating the need for manual intervention and effectively saving manpower.

[0053] like Figure 1 As shown, in one embodiment of the present application, the sample liquid transport mechanism includes: a third movable module and a pipetting pump 830. The third movable module includes a third horizontal slide connected to the movable slide 121 on the base plate 120 on the side away from the pipetting tip placement seat 700, an extension arm 810 connected to the third horizontal slide via a third horizontal slider, and a third vertical slide 820 connected to the extension arm 810; the pipetting pump 830 is connected to the third vertical slide 820 via a third vertical slider, and is used to grab the pipetting tip in the pipetting tip holder 701 and control the pipetting tip to drip sample liquid onto the slide when it reaches above the slide box 210.

[0054] Specifically, the extension arm 810 connected to the third horizontal slide rail via the third horizontal slider can move in the horizontal direction and can also extend in the direction perpendicular to the third horizontal slide rail. In addition, the pipette pump 830 is slidably connected to the third vertical slide rail 820 on the extension arm 810 via the third vertical slider. In this way, the horizontal and vertical positions of the pipette pump 830 can be controlled, effectively improving the accuracy during pipetting. In addition, the pipette pump 830 can grab the pipette tip in the pipette tip holder 701 and push the pipette tip when it reaches the top of the slide box 210 to add sample liquid to the slide. In this way, the automation of the pipetting process is achieved and production efficiency is improved.

[0055] like Figure 4As shown in the embodiment of the present application, the liquid-based thin-layer cell preparation machine further comprises a recovery box 910. The recovery box 910 is arranged on the base 110 and is used for recovering the pipette tip. The recovery box 910 is provided with a placing tube 911 for storing the test tube cap. Specifically, after the sample liquid in the pipette tip is consumed, the pipette pump 830 can move the pipette tip into the recovery box 910 to recover the pipette tip. In addition, since the test tube cap is provided with a cotton swab, the cotton swab contaminated with the sample liquid will drip the sample liquid downward and pollute the machine. Therefore, after the rotating clamp 614 of the cap opening device unscrews the test tube cap, the test tube cap can be placed into the placing tube 911 which is in communication with the recovery box 910. In this way, the cotton swab on the test tube cap can be prevented from polluting the machine, and the sample liquid dripped from the cotton swab can enter the recovery box 910 through the placing tube 911, thereby improving the recovery rate.

[0056] As shown in the embodiment of the present application, the base plate 120 on one side of the pipette tip support 701 is provided with a loading and unloading opening. Figure 3 and Figure 4 As shown in the embodiment of the present application, the base plate 120 on one side of the pipette tip support 701 is provided with a loading and unloading opening. Figure 5 and Figure 6 The liquid-based thin-layer cell preparation machine further comprises a cable containing rack 920 and a shell 930. The cable containing rack 920 is arranged on the base plate 120 away from the pipette tip support 701 and is provided with a cable containing cavity. The shell 930 is arranged on the cable containing rack 920 and the rack, and the shell 930 is provided with an upper flip cover 931 in communication with the cable containing cavity and a lower flip cover 932 in communication with the loading and unloading opening.

[0057] Specifically, the cable containing rack 920 can contain the cable used for controlling the above-mentioned mechanisms, thereby reducing the occupied space of the equipment and improving the degree of intensification. In addition, the cable containing rack 920 and the rack are further sleeved with the shell 930, which can effectively prevent contaminants from entering the interior of the machine, improve the cleanliness of the slide preparation environment, and prevent sample liquid pollution. In addition, the upper flip cover 931 of the shell 930 can be opened or closed by means of a gas spring, and the internal cable can be conveniently repaired. At the same time, the upper flip cover 931 is further provided with a touch screen 933, and the touch screen 933 is connected with each mechanism through a controller, so that each mechanism can be controlled, and the degree of automation of slide preparation is further improved. In addition, when the test tube or the pipette tip needs to be replaced or the slide needs to be added, the lower flip cover 932 can be opened to supplement, recover, or repair each mechanism. At the same time, the lower flip cover 932 is further provided with an observation window 934, which is convenient for the operator to observe the working condition of each mechanism, and further improves the production efficiency.

[0058] As shown in the embodiment of the present application, the base plate 120 on one side of the pipette tip support 701 is provided with a loading and unloading opening. Figure 4 、 Figure 5 and Figure 6As shown, in an embodiment of the present application, the shell 930 is provided with a slide output opening near one side of the slide supply mechanism, and the liquid-based thin-layer cell preparation machine further comprises an output belt line 940. The output belt line 940 is arranged in the slide output opening and extends away from the shell 930, and is used to output the slide outward. Specifically, after the preparation of the slide is completed, the slide conveying mechanism can extract the slide from the drying groove plate 310 of the slide drying mechanism 300, and transport the slide to the output belt line 940, and the output belt line 940 starts to transport the slide out of the preparation machine. Thus, the transfer process of the slide is realized, and the production efficiency is further improved.

[0059] The liquid-based thin-layer cell preparation machine of the present application integrates the slide centrifugation mechanism, the slide drying mechanism, the slide supply mechanism, the slide conveying mechanism, the test tube conveying mechanism and the sample liquid conveying mechanism, realizes the automation of slide preparation, effectively saves manpower and improves production efficiency.

[0060] The above is the preferred embodiment of the present application, it should be noted that for those skilled in the art, without departing from the principles of the present application, can make a number of improvements and refinements, these improvements and refinements should also be considered as the protection scope of the present application.

Claims

1. A liquid-based thin-layer cell preparer, comprising: The utility model relates to a kind of automatic sample preparation device, including: Rack, including base and two groups of base plate being symmetrically arranged on the base; Slide centrifugation mechanism, arranged on the base, including centrifuge frame, centrifugal drive device being arranged on the centrifuge frame and slide box being connected with the centrifugal drive device; Slide drying mechanism, arranged on the base, including drying machine and drying groove plate being arranged above the drying machine; Slide supply mechanism, arranged on the base, including slide storage device and slide lifting device being connected with the slide storage device; Slide conveying mechanism, arranged above the slide supply mechanism, for extracting slide from the slide supply mechanism, and sequentially transporting slide into the slide box and the drying groove plate; Test tube conveying mechanism, arranged on the base, for extracting test tube and opening test tube cover; Sample liquid conveying mechanism, arranged on the base, for extracting sample liquid in test tube using pipette tip and dropping sample liquid to slide transported into the slide box; Recycling box, arranged on the base, for recycling pipette tip, the recycling box is provided with placing tube for storing test tube cover, the placing tube is communicated with the recycling box, and the placing tube is also used for recycling sample liquid dropped by cotton swab on the test tube cover into the recycling box.

2. The liquid-based thin-layer cell preparator of claim 1, wherein, The slide storage device is provided with slide lifting outlet above.

3. The liquid-based thin-layer cell preparator of claim 1, wherein The slide conveying mechanism includes: First moving module, including first horizontal slide rail and first vertical slide rail connected with the first horizontal slide rail through first horizontal slide block, and the first horizontal slide rail is connected with the rack; Suction cup grabbing module, connected with the first vertical slide rail through first vertical slide block, including multi-way suction tube and suction cup connected with the multi-way suction tube; Negative pressure vacuum pump, connected with the multi-way suction tube, for providing negative pressure to the suction cup.

4. The liquid-based thin-layer cell preparator of claim 1, wherein, Further including: Sample rack, detachably connected with the base, for storing test tube.

5. The thin-layer liquid-based cell preparator according to claim 4, wherein The base plate is formed with moving slide rail at one end away from the base, and the base is provided with test tube fixing socket, and the test tube conveying mechanism includes: Second moving module, including second horizontal slide rail slidably connected with the moving slide rail, and second vertical slide rail connected with the second horizontal slide rail through second horizontal slide block; Cover opening device, connected with the second vertical slide rail through second vertical slide block, including cover opening motor and rotating clamp jaw connected with the cover opening motor, and the rotating clamp jaw is used for clamping test tube in the sample rack and extracting into the test tube fixing socket for fixation and cover opening.

6. The thin-layer liquid-based cell preparator according to claim 5, wherein Further including: Pipette tip placing seat, hollow containing opening is formed on the pipette tip placing seat; Pipette tip support, for being installed in the containing opening, and the pipette tip support is provided with a plurality of plate holes for accommodating pipette tip.

7. The thin-layer liquid-based cell preparator according to claim 6, wherein The sample liquid conveying mechanism includes: Third moving module, including third horizontal slide block connected with the moving slide rail on the base plate away from the pipette tip placing seat side, extending arm connected with the third horizontal slide block and third vertical slide rail connected with the extending arm; A pipette pump is connected with the third vertical sliding rail through a third vertical sliding block, used for grabbing the pipette tip in the pipette tip holder and controlling the pipette tip to drop sample liquid on the slide when reaching above the slide box.

8. The thin-layer liquid-based cell preparator according to claim 1, wherein The base plate on the side close to the pipette tip holder is provided with a loading and unloading opening, and the liquid-based thin-layer cell preparation machine further comprises: A cable containing rack is arranged on the base plate away from the pipette tip holder, and the cable containing rack is provided with a cable containing cavity; A shell is arranged on the cable containing rack and the rack, and the shell is respectively provided with an upper flip cover communicated with the cable containing cavity and a lower flip cover communicated with the loading and unloading opening.

9. The thin-layer liquid-based cell preparator of claim 8, wherein, The shell is provided with a slide output opening on the side close to the slide feeding mechanism, and the liquid-based thin-layer cell preparation machine further comprises: An output belt line is arranged in the slide output opening and extends away from the shell, used for outputting the slide outward.

Citation Information

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