Signal acquisition method, device, mass spectrometer and computer storage medium

Abstract

The present application relates to the field of mass spectrometers, and discloses a signal acquisition method, apparatus, mass spectrometer, and computer storage medium. The method includes: sampling an analog signal through an ADC acquisition card to obtain the signal intensity of the analog signal at each sampling point; comparing the signal intensity of each sampling point with a preset intensity threshold, and determining the type of each sampling point according to the comparison result; performing cumulative counting on each sampling point according to the type of each sampling point to obtain a cumulative result; wherein, the cumulative result is used to convert through the time corresponding to each sampling point and the count value, so as to obtain a mass spectrum. In the embodiment of the present application, by expanding the digital counting function on a single ADC acquisition card, there is no need to additionally increase a TDC acquisition card and other hardware circuit structures, which simplifies the structure of the mass spectrometer and improves the applicability of the mass spectrometer.

Description

Technical Field

[0001] This application relates to the field of mass spectrometers, and particularly to a signal acquisition method, apparatus, mass spectrometer, and computer storage medium. Background Art

[0002] Currently, only one data acquisition system is installed on a mass spectrometer to meet the application requirements of different data and signal acquisitions, and the data acquisition system is implemented by an ADC acquisition card or a TDC acquisition card accordingly; among them, the ADC acquisition card only has the function of waveform digitization, while the TDC acquisition card only has the function of digital counting.

[0003] Furthermore, when it is necessary to simultaneously implement the functions of waveform digitization and digital counting, it is necessary to integrate an ADC acquisition card and a TDC acquisition card on a mass spectrometer at the same time. When integrating two acquisition cards on a mass spectrometer at the same time, additional hardware structures are required accordingly, which increases the structural complexity and manufacturing cost of the mass spectrometer, and thus reduces the applicability of the mass spectrometer. Summary of the Invention

[0004] In view of this, to solve the deficiencies of the prior art, this application provides a signal acquisition method, apparatus, mass spectrometer, and computer storage medium.

[0005] In a first aspect, this application provides a signal acquisition method applied to a mass spectrometer, where the mass spectrometer includes an ADC acquisition card, and the method includes:

[0006] Sampling an analog signal through the ADC acquisition card to obtain the signal intensity of the analog signal at each sampling point;

[0007] Comparing the signal intensity of each sampling point with a preset intensity threshold, and determining the type of each sampling point according to the comparison result;

[0008] Accumulatively counting each sampling point according to the type of each sampling point to obtain an accumulation result; 5 where the accumulation result is used to convert through the time corresponding to each sampling point and the count value, and then

[0009] obtain a mass spectrum.

[0010] In an optional implementation manner, the determining the type of each sampling point according to the comparison result includes:

[0011] If the signal intensity of the sampling point is greater than or equal to the preset intensity threshold, then mark the sampling

[0012] point as a signal point;

[0013] 0 If the signal intensity of the sampling point is less than the preset intensity threshold, then mark the sampling point as

[0014] It is denoted as a noise point; wherein, the preset intensity threshold is greater than the maximum noise intensity and less than the signal intensity of the minimum signal peak of the analog signal.

[0015] In an alternative embodiment, the step of assigning values to each sampling point according to the type of each sampling point and sequentially accumulating and counting includes:

[0016] Assigning a value of 0 to each of the noise points and a value of 1 to each of the signal points;

[0017] Sequentially accumulating the values of each of the sampling points.

[0018] In an alternative embodiment, the method further includes:

[0019] Determining the accumulated count value of each of the sampling points according to the accumulated result;

[0020] Generating a mass spectrum according to the time corresponding to each of the sampling points and the accumulated count value; wherein, the abscissa of the mass spectrum is time and the ordinate is the accumulated count value.

[0021] In an alternative embodiment, the step of sampling the analog signal through the ADC acquisition card to obtain the signal intensity of each sampling point includes:

[0022] Sampling the analog signal periodically through the ADC acquisition card according to a predetermined sampling period to obtain the signal intensity of each sampling point within each sampling period.

[0023] In an alternative embodiment, the step of performing cumulative counting on each sampling point according to the type of each sampling point to obtain an accumulated result includes:

[0024] Performing cumulative counting on each sampling point within each sampling period respectively to obtain the accumulated result corresponding to each sampling period.

[0025]

[0026]

[0027]

[0028] The detector is configured to generate an analog signal;

[0028] The ADC acquisition card is used to sample the analog signal, obtain the signal intensity of the analog signal at each sampling point; compare the signal intensity of each sampling point with a preset intensity threshold, and determine the type of each sampling point according to the comparison result; according to the type of each sampling point, perform cumulative counting on each sampling point to obtain a cumulative result; wherein, the cumulative result is used to convert through the time corresponding to each sampling point and the count, so as to obtain a mass spectrum.

[0029] In an alternative embodiment, the mass spectrometer further includes a preamplifier;

[0030] The preamplifier is used to amplify the analog signal from the detector and input the amplified analog signal to the ADC acquisition card for sampling.

[0031] In a third aspect, the present application provides a signal acquisition device, including the mass spectrometer and a host computer as described in any one of the foregoing embodiments;

[0032] The host computer is used to receive the cumulative result from the mass spectrometer, and determine the time corresponding to each sampling point and the cumulative count value according to the cumulative result, and generate a mass spectrum.

[0033] In a fourth aspect, the present application provides a computer storage medium, which stores a computer program, and when the computer program is executed, it implements the signal acquisition method described above.

[0034] The embodiments of the present application have the following beneficial effects:

[0035] In the embodiments of the present application, the ADC acquisition card samples the analog signal to obtain the signal intensity of the analog signal at each sampling point; compares the signal intensity of each sampling point with a preset intensity threshold, and determines the type of each sampling point according to the comparison result; according to the type of each sampling point, performs cumulative counting on each sampling point to obtain a cumulative result; wherein, the cumulative result is used to convert through the time corresponding to each sampling point and the count value, so as to obtain a mass spectrum. By expanding the digital counting function on a single ADC acquisition card in the embodiments of the present application, the ADC acquisition card simultaneously has the functions of digital counting and waveform digitization, thus eliminating the need to additionally add a TDC acquisition card and other hardware circuit structures, reducing the structural complexity of the mass spectrometer, correspondingly reducing the manufacturing cost of the mass spectrometer, and improving the applicability of the mass spectrometer. Description of the Drawings

[0036] In order to more clearly illustrate the technical solutions of the present application, the drawings required for use in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of the present application, and therefore should not be regarded as limiting the protection scope of the present application. In each drawing, similar components are numbered similarly.

[0037] Figure 1 It shows a schematic diagram of sampling points after the ADC acquisition card samples the analog signal;

[0038] Figure 2 It shows a schematic diagram of the first implementation manner of the signal acquisition method in the embodiment of the present application;

[0039] Figure 3 It shows a schematic diagram of the second implementation manner of the signal acquisition method in the embodiment of the present application;

[0040] Figure 4 It shows a schematic diagram of the third implementation manner of the signal acquisition method in the embodiment of the present application;

[0041] Figure 5 It shows a schematic diagram of the process of converting the cumulative result into a mass spectrum in the embodiment of the present application;

[0042] Figure 6 It shows a schematic diagram of a structure of a mass spectrometer in the embodiment of the present application;

[0043] Figure 7 It shows a schematic diagram of a structure of a signal acquisition device in the embodiment of the present application. Detailed implementation manners

[0044] Next, the technical solutions in the embodiments of the present application will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments.

[0045] Generally, the components of the embodiments of the present application described and shown in the drawings here can be arranged and designed in various different configurations. Therefore, the following detailed description of the embodiments of the present application provided in the drawings is not intended to limit the scope of the present application claimed, but merely represents the selected embodiments of the present application. All other embodiments obtained by those skilled in the art based on the embodiments of the present application without creative efforts belong to the scope of protection of the present application.

[0046] In the following text, the terms "including", "having" and their cognates that can be used in various embodiments of the present application are only intended to represent specific features, numbers, steps, operations, elements, components or combinations of the foregoing items, and should not be construed as first excluding the existence of one or more other features, numbers, steps, operations, elements, components or combinations of the foregoing items or increasing the possibility of one or more features, numbers, steps, operations, elements, components or combinations of the foregoing items.

[0047] In addition, the terms "first", "second", "third", etc. are only used for distinguishing descriptions and cannot be understood as indicating or implying relative importance.

[0048] Unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the various embodiments of this application belong. The terms (such as those defined in a general-use dictionary) will be interpreted to have the same meaning as the contextual meaning in the relevant technical field and will not be interpreted to have an idealized meaning or an overly formal meaning unless clearly defined in the various embodiments of this application.

[0049] A time-of-flight mass spectrometer (hereinafter referred to as a mass spectrometer for short) has the advantages of simple structure, fast analysis speed, high resolution and sensitivity, and wide mass range. It can achieve a microsecond-level fast response speed and simultaneous measurement of the full spectrum. Currently, it is widely used in the fields of real-time rapid analysis and on-line monitoring. Currently, based on the time-of-flight mass spectrometer and the signal acquisition card, technologies based on analog-to-digital conversion (ADC) and time-to-digital conversion (TDC) can be realized. Among them, the signal acquisition card includes an ADC acquisition card, a TDC acquisition card, etc.

[0050] The principle of the ADC acquisition card is to discretely sample the original analog electrical signal from the mass spectrometer detector to obtain a discrete time sample, and use these discrete time sample values to reconstruct the original analog electrical signal. Its signal reconstruction process is also called waveform digitization. The ADC acquisition card has the characteristic of a wide dynamic range, can detect two beams of ions that arrive almost simultaneously, and there is no offset phenomenon caused by dead time; however, in actual use, there are also disadvantages such as high noise and low signal-to-noise ratio (Signal-to-Noise). Currently, high-speed ADC data acquisition cards also have the characteristics of complex technology and high cost.

[0051] In contrast, the TDC acquisition card has the advantages of simple structure, low power consumption, and easy implementation of ultra-high-precision time measurement, but there are also deficiencies such as dead time and low dynamic range. The principle of the TDC acquisition card is based on electronic technology to represent the time information of the event signal in a digital manner. Usually, in applications, the relative time interval information between two or more pulse signals is given. The counter starts counting after receiving the start pulse signal and determines whether to count according to the set threshold (Threshold). In a single test, the sampling points with a signal intensity greater than the threshold at the sampling points are recorded as the value 1, otherwise 0; after repeated accumulation, the cumulative spectrum corresponding to the event signal can be obtained.

[0052] However, currently, when implementing waveform digitization and digital counting functions through a time-of-flight mass spectrometer, it is necessary to integrate an ADC acquisition card and a TDC acquisition card simultaneously, which correspondingly increases hardware devices such as a constant fraction discriminator (CFD) circuit. This results in a more complex structure of the mass spectrometer, limits its application range, and has a higher manufacturing cost and lower applicability.

[0053] Based on this, the embodiments of the present application provide a signal acquisition method and a mass spectrometer. By using a single ADC acquisition card to implement waveform digitization and digital counting functions, the application range of the ADC acquisition card is expanded, and the applicability of the mass spectrometer is improved.

[0054] Embodiment 1

[0055] The embodiments of the present application provide a signal acquisition method, which is applied to a mass spectrometer. The mass spectrometer is a time-of-flight mass spectrometer, and the mass spectrometer includes a detector and an ADC acquisition card. Optionally, the detector and the ADC acquisition card are connected through a signal transmission line, and the signal transmission line can be a high-frequency radio frequency line. Further, the impedance matching of the high-frequency radio frequency line is 50 ohms and has a good anti-interference shielding effect.

[0056] Exemplarily, the ADC acquisition card is used to discretely sample the analog signal (i.e., analog electrical signal) generated by the detector to obtain a discrete time sample (i.e., discrete sampling point), and based on these discrete time sample values, a waveform diagram of the original analog signal is constructed according to the discrete sampling points to implement the waveform digitization function of the ADC acquisition card.

[0057] As Figure 1 shown, the waveform diagram of the reconstructed original analog signal has multiple signal peaks, such as signal peaks numbered 1, 2, and 3. Each signal peak corresponds to a peak value, and the peak value is the signal intensity corresponding to the sampling point at the vertex of the signal peak.

[0058] As an optional implementation manner, the mass spectrometer further includes a preamplifier. When the amplitude of the analog signal output by the detector is small, the analog signal from the detector is amplified by the preamplifier on the mass spectrometer, and then the amplified analog signal is input to the ADC acquisition card for sampling to improve the quality of signal sampling, and further facilitate subsequent waveform digitization and digital counting based on the sampling results, improving the reliability of waveform digitization and digital counting.

[0059] Please refer to Figure 2 , and the following will provide a detailed description of this signal acquisition method.

[0060] S10, sample the analog signal through the ADC acquisition card to obtain the signal intensity of the analog signal at each sampling point.

[0061] The continuous analog signal is sampled by an ADC acquisition card, and the signal strength of the analog signal at each sampling point is correspondingly obtained.

[0062] Specifically, in this embodiment, the continuous analog signal is discretely sampled by an ADC acquisition card to obtain discrete sampling points, and the signal strength of the analog signal at each sampling point is recorded.

[0063] As an alternative solution, according to a predetermined sampling period, the analog signal is periodically sampled by an ADC acquisition card to obtain the signal strength of each sampling point within each sampling period; the cumulative counting is respectively performed on each sampling point within each sampling period to obtain the cumulative result corresponding to each sampling period.

[0064] S20. Compare the signal strength of each sampling point with a preset strength threshold, and determine the type of each sampling point according to the comparison result.

[0065] For the sampled analog signal, due to various sources of noise during the sampling process, a preset strength threshold is set for determination. When the signal strength at the sampling point is greater than the set preset strength threshold, the sampling point is determined as a signal point, otherwise the sampling point is determined as a noise point.

[0066] Furthermore, compare the signal strength at each sampling point with the preset strength threshold (i.e., Threshold), and then determine whether each sampling point is a noise point according to the comparison result. The specific value of the preset strength threshold is not limited here. For example, it can be set that the value of the preset strength threshold needs to be greater than the maximum noise strength and less than the signal strength of the smallest signal peak in the analog signal. Usually, the maximum noise strength and the signal strength value of the smallest signal peak in the analog signal can be determined according to the experimental environment and experimental conditions.

[0067] In one embodiment, as Figure 3 shown, the step of "determining the type of each analog signal according to the comparison result" in the above step S20 further specifically includes the following steps:

[0068] S21. If the signal strength of the sampling point is greater than or equal to the preset strength threshold, mark the sampling point as a signal point.

[0069] S22. If the signal strength of the sampling point is less than the preset strength threshold, mark the sampling point as a noise point.

[0070] That is, according to the comparison result of the signal strength of each sampling point with the preset strength threshold, determine the noise points and signal points of each sampling point.

[0071] As Figure 1 shown, this signal point is Figure 1Sampling points above a preset intensity threshold, and noise points are sampling points below the preset intensity threshold.

[0072] S30. According to the types of each sampling point, perform cumulative counting on each sampling point to obtain a cumulative result; wherein, the cumulative result is used to convert through the time corresponding to each sampling point and the count value, and then obtain a mass spectrometry graph.

[0073] After determining the noise points and signal points of each sampling point, assign values to the noise points and signal points respectively, and perform cumulative counting (i.e., cumulative addition) in sequence to obtain a cumulative result.

[0074] It can be understood that in this embodiment, when the ADC acquisition card uses the digital counting function, the value of the sampling point recorded by its memory is no longer the actually measured analog signal value, but the value assigned to each sampling point in this step.

[0075] In short, in this embodiment, by expanding the usage function of the ADC acquisition card, on the basis of the original waveform digitization function of the ADC acquisition card, the setting of a preset intensity threshold is added during sampling, so as to implement the digital counting function of the TDC acquisition card on the ADC acquisition card.

[0076] In one embodiment, as Figure 4 shown, the above step S30 specifically includes the following steps:

[0077] S31. Assign 0 to each noise point and assign 1 to each signal point.

[0078] S32. Cumulatively add the values of each sampling point in sequence.

[0079] It can be understood that assign 0 to each noise point and assign 1 to each signal point, so that when performing cumulative counting, only the signal points are counted, and then the number of all signal points in the current sampling can be obtained.

[0080] As an optional solution, as Figure 5 shown, according to the cumulative results of each sampling point in each sampling period, convert them into a time-digital conversion mass spectrometry graph (i.e., a mass spectrometry graph).

[0081] Specifically, according to the cumulative result, determine the cumulative count value of each sampling point; according to the time corresponding to each sampling point and the cumulative count value, generate a mass spectrometry graph; wherein, the abscissa of the mass spectrometry graph is the time corresponding to the sampling point, and the ordinate is the cumulative count value of the sampling point.

[0082] Further, in this embodiment, after periodic cyclic sampling, the assignments (0 or 1) of each sampling point are accumulated to obtain the accumulated value of each sampling point. The accumulated value of each sampling point is output to the connected host computer, and the corresponding application program or software in the host computer sorts out the time and accumulated value corresponding to each sampling point, and correspondingly draws the time-digital conversion mass spectrometry diagram corresponding to each sampling period.

[0083] In the first aspect of the embodiment of the present application, by expanding the digital counting function on a single ADC acquisition card, the ADC acquisition card simultaneously has the functions of digital counting and waveform digitization, so that there is no need to additionally add a TDC acquisition card and other hardware circuit structures, reducing the structural complexity of the mass spectrometer, correspondingly reducing the manufacturing cost of the mass spectrometer, and improving the applicability of the mass spectrometer; at the same time, the use mode of the ADC acquisition card can be flexibly adjusted according to different requirements, so as to meet different application requirements; in the second aspect, by accumulating the counting results, it is convenient to subsequently generate the mass spectrometry diagram of the analog signal correspondingly, realizing the efficient use of the ADC acquisition card.

[0084] Embodiment 2

[0085] Please refer to Figure 6 , the embodiment of the present application provides a mass spectrometer 100, including a detector 110 and an ADC acquisition card 120; the detector 110 and the ADC acquisition card 120 are connected by a high-frequency RF line.

[0086] The detector 110 is used to output an analog signal; the ADC acquisition card 120 is used to sample the analog signal, obtain the signal intensity of the analog signal at each sampling point; compare the signal intensity of each sampling point with a preset intensity threshold, and determine the type of each sampling point according to the comparison result; according to the type of each sampling point, perform cumulative counting on each sampling point to obtain a cumulative result; wherein, the cumulative result is used to convert through the time corresponding to each sampling point and the count to obtain a mass spectrometry diagram.

[0087] The above-mentioned mass spectrometer 100 is used to execute the steps of the signal acquisition method in the above-mentioned Embodiment 1; any optional items in Embodiment 1 are also applicable to this embodiment, and will not be elaborated here.

[0088] Embodiment 3

[0089] Please refer to Figure 7 , the embodiment of the present application further provides a signal acquisition device 1000, including a mass spectrometer 100 and a host computer 200.

[0090] The host computer 200 is used to receive the cumulative result from the mass spectrometer 100, and determine the time and cumulative count value corresponding to each sampling point according to the cumulative result, and generate a mass spectrometry diagram.

[0091] The above-mentioned mass spectrometer 100 is used to implement the mass spectrometer 100 in the above-mentioned Embodiment 2; any optional items in Embodiment 2 are also applicable to this embodiment and will not be elaborated here.

[0092] An embodiment of the present application also provides a computer storage medium storing machine-executable instructions. When the computer-executable instructions are called and run by a processor, the computer-executable instructions cause the processor to run the steps of the signal acquisition method in the above-mentioned embodiment.

[0093] In several embodiments provided by the present application, it should be understood that the disclosed devices and methods can also be implemented in other ways. The device embodiments described above are only illustrative. For example, the flowcharts and structure diagrams in the accompanying drawings show the possible architectures, functions, and operations of devices, methods, and computer program products according to multiple embodiments of the present application. In this regard, each block in the flowchart or block diagram can represent a module, a program segment, or a part of code, and the module, program segment, or part of code contains one or more executable instructions for implementing the specified logical function. It should also be noted that in an alternative implementation, the functions marked in the block can occur in a different order than marked in the accompanying drawings. For example, two consecutive blocks can actually be executed substantially in parallel, and they can sometimes be executed in the reverse order, depending on the functions involved. It should also be noted that each block in the structure diagram and / or flowchart, as well as the combination of blocks in the structure diagram and / or flowchart, can be implemented by a dedicated hardware-based system for performing the specified functions or actions, or can be implemented by a combination of dedicated hardware and computer instructions.

[0094] In addition, each functional module or unit in various embodiments of the present application can be integrated together to form an independent part, or each module can exist separately, or two or more modules can be integrated to form an independent part.

[0095] When the above-mentioned functions are implemented in the form of software function modules and sold or used as independent products, they can be stored in a computer-readable storage medium. Based on such an understanding, the technical solution of this application, in essence, or the part that contributes to the prior art, or a part of this technical solution, can be embodied in the form of a software product. This computer software product is stored in a storage medium and includes several instructions for causing a computer device (which may be a smart phone, a personal computer, a server, or a network device, etc.) to execute all or part of the steps of the methods in various embodiments of this application. The foregoing storage medium includes: various media that can store program codes, such as USB flash drives, mobile hard disks, read-only memories (ROMs), random access memories (RAMs), magnetic disks, or optical discs.

[0096] The above is only the specific implementation manner of this application, but the protection scope of this application is not limited thereto. Any person skilled in the art within the technical scope disclosed by this application can easily think of changes or substitutions, which should all be covered within the protection scope of this application.

Claims

1. A mass spectrometer, characterized in that, It includes a detector and an ADC acquisition card; the detector and the ADC acquisition card are connected by a high-frequency RF cable; The detector is used to generate an analog signal; The ADC acquisition card is used to sample the analog signal to construct a waveform diagram of the analog signal, determine the signal strength of the analog signal at each sampling point according to the waveform diagram; compare the signal strength of each sampling point with a preset strength threshold, and determine the type of each sampling point according to the comparison result; assign values to each sampling point according to the type of each sampling point, and perform cumulative counting according to the assignment result to obtain a cumulative result; wherein, the cumulative result is used to convert through the time corresponding to each sampling point and the count to obtain a mass spectrum.

2. The mass spectrometer according to claim 1, characterized in that, The determining the type of each sampling point according to the comparison result includes: If the signal strength of the sampling point is greater than or equal to the preset strength threshold, mark the sampling point as a signal point; If the signal strength of the sampling point is less than the preset strength threshold, mark the sampling point as a noise point; wherein, the preset strength threshold is greater than the maximum noise strength and less than the signal strength of the minimum signal peak of the analog signal.

3. The mass spectrometer according to claim 2, wherein The assigning values to each sampling point according to the type of each sampling point, and performing cumulative counting according to the assignment result to obtain a cumulative result includes: Assign 0 to each of the noise points and assign 1 to each of the signal points; Accumulate the values of each of the sampling points in sequence.

4. The mass spectrometer according to claim 1, characterized in that, The mass spectrometer is further used for: Determine the cumulative count value of each of the sampling points according to the cumulative result; Generate a mass spectrum according to the time corresponding to each of the sampling points and the cumulative count value; wherein, the abscissa of the mass spectrum is time and the ordinate is the cumulative count value.

5. The mass spectrometer according to claim 1, characterized in that, The sampling the analog signal by the ADC acquisition card to obtain the signal strength of each sampling point includes: Periodically sample the analog signal by the ADC acquisition card according to a predetermined sampling period to obtain the signal strength of each sampling point within each sampling period.

6. The mass spectrometer according to claim 1 or 5, characterized in that, The assigning values to each sampling point according to the type of each sampling point, and performing cumulative counting according to the assignment result to obtain a cumulative result includes: Perform cumulative counting on each sampling point within each sampling period respectively to obtain the cumulative result corresponding to each sampling period.

7. The mass spectrometer according to claim 1, characterized in that, The mass spectrometer further includes a preamplifier; The preamplifier is used to amplify the analog signal from the detector and input the amplified analog signal to the ADC acquisition card for sampling.

8. A signal acquisition method, characterized in that, Applied to the mass spectrometer according to any one of claims 1-7; the method includes: The detector generates an analog signal; The ADC acquisition card samples the analog signal to construct a waveform diagram of the analog signal, determine the signal strength of the analog signal at each sampling point according to the waveform diagram; compare the signal strength of each sampling point with a preset strength threshold, and determine the type of each sampling point according to the comparison result; assign values to each sampling point according to the type of each sampling point, and perform cumulative counting according to the assignment result to obtain a cumulative result; wherein, the cumulative result is used to convert through the time corresponding to each sampling point and the count to obtain a mass spectrum.

9. A signal acquisition device, characterized in that, Comprising a mass spectrometer as described in any one of claims 1-7 and a host computer; The host computer is used to receive the cumulative result from the mass spectrometer, and determine the time corresponding to each sampling point and the cumulative count value according to the cumulative result, and generate a mass spectrum.

10. A computer storage medium, characterized in that, It stores a computer program, and when the computer program is executed, it implements the signal acquisition method according to claim 8.

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