A gene testing kit for childhood asthma
By employing a multi-door support and positioning components in the pediatric asthma gene testing kit, the problems of damage and spillage of reagent bottles during transportation are solved, achieving stable positioning and uniform heating of test tubes, and ensuring safe transportation and preservation of samples.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- GENERAL HOSPITAL OF THE NORTHERN WAR ZONE OF THE CHINESE PEOPLES LIBERATION ARMY
- Filing Date
- 2023-02-16
- Publication Date
- 2026-05-26
AI Technical Summary
Existing childhood asthma gene testing kits are prone to damage during transportation due to collisions or accidents, resulting in sample spillage. They lack effective shock absorption and sealing protection.
A gene testing kit for childhood asthma was designed. The kit uses a box with multiple openings, and includes a support and telescopic drive assembly. The test tubes are stably positioned by horizontal and vertical positioning components. Combined with a temperature control assembly and a flexible sealing plug, the kits achieve horizontal and vertical shock absorption protection and uniform heating.
It effectively prevents test tubes from breaking and samples from spilling during transportation, ensuring the safety of sample preservation and achieving uniform and efficient heating and insulation effects to meet sample preservation requirements.
Smart Images

Figure CN116238789B_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of medical device technology, and in particular to a gene detection kit for childhood asthma. Background Technology
[0002] The testing of genes for childhood asthma requires the use of a kit to hold the collected DNA. The kit is a box used to hold chemical reagents for detecting chemical components, drug residues, virus types, etc., and is commonly used in hospitals and pharmaceutical companies.
[0003] A search revealed that Chinese patent number CN 210916023 U discloses a gene detection kit for childhood asthma, comprising a lid, a reagent tube, and a battery. The lid has a handle attached to its top, with an anti-slip rubber pad on its outer side. An antibacterial airbag is installed below the lid, which is connected to a box body via a rotating shaft. The box body contains a protective sponge, and a refrigerant placement cylinder is installed at its center. The reagent tube passes through the protective sponge, and a buffer plate is located below the reagent tube. The lower surface of the buffer plate is connected to the box body via a buffer spring, and a heating tube is located below the buffer plate. The battery is located on the outside of the box body, and a heating switch is located above the battery.
[0004] The existing technology has the following shortcomings: When storing the reagent bottle containing the sample, the existing reagent kit only uses a spring in one direction to shock absorb and protect the reagent bottle. Even if there is a protective sponge for additional protection, the reagent bottle is still easily damaged by collision or accident during transportation, or the sample inside the reagent bottle may spill. Therefore, the present invention proposes a new gene detection kit for childhood asthma. Summary of the Invention
[0005] The purpose of this invention is to address the deficiencies in the existing technology by proposing a gene detection kit for childhood asthma.
[0006] To achieve the above objectives, the present invention adopts the following technical solution:
[0007] A gene testing kit for childhood asthma includes a box body with multiple openings around its perimeter. A support is located on the bottom plate inside the box body, and a temperature control component is provided on the support and the top plate of the box body. Multiple telescopic frames are connected around the support via telescopic drive components, and each telescopic frame is connected to a movable door. Each movable door is provided with a lateral positioning component for positioning test tubes. A vertical positioning component is provided on the support near the telescopic frames and movable doors. The test tubes are laterally positioned and rotated by the lateral positioning components, and vertically positioned and sealed by the vertical positioning components.
[0008] Furthermore, the temperature control component includes a pipe fixed inside the box, a heater and a fan installed inside the pipe, an air hole at the top of the top plate of the box corresponding to the top of the pipe, multiple air ducts connected to the bottom of the pipe, an air outlet at the end of the air duct away from the pipe, and the air outlet corresponding to the sliding door and the test tube. The temperature control component also includes a temperature sensor and a controller. The temperature sensor monitors the temperature inside the pipe and the box, and the controller controls the start and stop of the heater and the fan.
[0009] Furthermore, the support includes a central plate fixed to the bottom plate of the box, and multiple sliding plates are installed radially outward from the center of the central plate. Each of the multiple sliding plates has an upright installed upward at the end away from the central plate. The end of the air duct with the air outlet is connected to the side of the upright, and the air outlet of the air duct corresponds to the test tube.
[0010] The telescopic frame includes a slide plate that is slidably installed with the slide rail plate. A perforated plate is installed at one end of the slide plate near the center plate, and the other end of the slide plate is connected and fixed to the sliding door. A vertical plate is installed upward at the end of the slide plate near the sliding door.
[0011] The telescopic drive assembly includes a drive gear disk rotatably mounted on the top surface of the center plate. The center gear is driven by a first motor, which is fixed on the bottom plate of the box. It also includes a lead screw mounted on the upper side of the slide plate and rotatably mounted with the upright. The lead screw is threadedly mounted to the lead hole plate. A driven gear is mounted on one end of the lead screw near the center plate, and the driven gear meshes with the drive gear disk.
[0012] The first motor drives the active gear disk to mesh with the driven gear, and controls the threaded plate, slide plate and movable door to slide laterally relative to the box body through the lead screw. The movable door and the door opening are sealed and connected or separated.
[0013] Furthermore, the movable door includes a base that slides and fits against the bottom plate of the box body. One side of the base is connected to the sliding plate of the telescopic frame, and a sealing plate is installed on the other side. The sealing plate is sealed and fitted with the door opening. The lateral positioning component is installed on the base for lateral positioning of the test tube and for controlling the lateral rotation of the test tube.
[0014] Furthermore, the lateral positioning assembly includes multiple vertical spring slide rods fixed on the base. A support ring is slidably mounted on the upper end of the multiple vertical spring slide rods. A rotating seat is movably mounted at the center of the support ring. Multiple vertical rods are fixed on the upper side of the support ring. A fixing ring is mounted on the upper part of the vertical rods. A clamping block is movably mounted on the inner side of the fixing ring through the lateral spring slide rods. The clamping block has a uniform diameter arc surface on the side near the center of the fixing ring and a variable diameter arc surface with the diameter gradually increasing from top to bottom on the upper part. The surface of the uniform diameter arc surface is provided with anti-slip texture.
[0015] Furthermore, the rotating seat includes a grooved rotating plate rotatably mounted with the support ring. The top surface of the grooved rotating plate is provided with a groove that matches the bottom of the test tube. The bottom surface of the grooved rotating plate is connected to the drive shaft of the second motor through a square sliding sleeve rod. The square sliding sleeve rod includes a square sleeve and a square sub-rod that are slidably mounted on each other. The lower end of the square sleeve is connected to the drive shaft of the second motor, and the upper end of the square sub-rod is fixedly connected to the bottom surface of the grooved rotating plate.
[0016] Furthermore, the vertical positioning assembly includes a first movable plate and a second movable plate movably disposed on the upper end of the stand, with the second movable plate located above the first movable plate. The first movable plate is movably installed to the upper end of the stand via a first torsion spring shaft. The lower end of the first movable plate extends between the stand and the upright plate and slides in contact with the side of the upright plate. The upper end of the first movable plate extends to the other side of the stand and slides in contact with the lower surface of one end of the second movable plate. The second movable plate is movably installed to the upper end of the stand via a second torsion spring shaft. One end of the second movable plate extends above the horizontal positioning assembly and is located on the side of the stand closer to the upright plate, while the other end extends to the other side of the stand away from the horizontal positioning assembly and the upright plate. A flexible sealing plug is installed on the bottom surface of the end of the second movable plate near the horizontal positioning assembly. The flexible sealing plug slides and seals the inside of the test tube opening. The flexible sealing plug is formed by stacking multiple rubber sheets along the axial direction of the shaft.
[0017] Furthermore, the flexible sealing plug is rotatably mounted to the second movable plate via a shaft. The top surface of the second movable plate and the upper end of the vertical plate are jointly provided with a rotation control assembly. The rotation control assembly includes a rotating shaft and a sub-shaft rotatably mounted on the top surface of the second movable plate. The rotating shaft and the sub-shaft are driven by meshing through a bevel gear set. A worm is installed at the end of the rotating shaft away from the sub-shaft and the bevel gear set. A worm wheel is installed at the upper end of the shaft of the flexible sealing plug. The worm and the worm wheel are driven by meshing.
[0018] The second gear is installed at the end of the sub-shaft away from the bevel gear set, and the first gear is fixed at the upper end of the upright. The second gear meshes with the first gear and moves in a circular motion around the first gear.
[0019] Furthermore, a wedge-shaped extruder is installed on the bottom plate of the box body at the position corresponding to each support ring. The end of the wedge-shaped extruder near the support ring is provided with a downwardly oriented wedge-shaped surface. The lower surface of the wedge-shaped extruder and the wedge-shaped surface are in separable sliding contact with the upper surface of the support ring.
[0020] The inner wall of the sealing plate and the outer side of each fixing ring are fixed with an arc-shaped ring component by the fixing plate, and the inner side of the upper end of the arc-shaped ring component is provided with an arc surface.
[0021] The transverse spring slide rod includes a slide tube that is slidably mounted transversely with the fixed ring. A crossbar is slidably mounted on one end of the slide tube near the clamping block via a limiting ring, and the end of the crossbar away from the slide tube is fixed to the outer surface of the clamping block. The end of the slide tube away from the clamping block extends to the outside of the fixed ring and is fixed with a frustum block. The frustum block slides in contact with the arc surface at the upper end of the arc-shaped ring. A first spring is sleeved on one end of the slide tube extending to the outside of the fixed ring, and a second spring is sleeved on the crossbar. One end of the second spring is fixed to the end of the slide tube, and the other end is fixed to the outer surface of the clamping block.
[0022] Compared with the prior art, the beneficial effects of the present invention are as follows:
[0023] 1. In this invention, the test tube containing the sample is first positioned by a horizontal positioning component, so that it can be stably placed on the base of the moving door. The moving door and the door opening of the box are closed by a telescopic drive component and a telescopic frame. During the closing process, the test tube is gradually positioned and sealed by a vertical positioning component, so that the test tube can be stably positioned inside the box. In addition, during subsequent transportation, the test tube can be protected against horizontal and vertical shock absorption, effectively preventing the test tube from breaking and preventing the internal sample from spilling out, thus ensuring the safety of sample preservation.
[0024] 2. In this invention, after the test tube is positioned, the heat preservation component heats and keeps the inside of the box, so that the sample inside the test tube is at a suitable storage temperature. Furthermore, during heating, the test tube is rotated axially, which makes the test tube and the sample inside heated more evenly and more quickly, and the storage temperature of the sample is adjusted more conveniently.
[0025] In summary, this invention enables safe, stable, and convenient preservation of test tubes and their internal samples, ensuring that the test tubes will not break or the samples will spill during transportation due to external impacts or vibrations. It also provides uniform and efficient heating and insulation for the test tubes and samples, better meeting the needs of sample preservation. Attached Figure Description
[0026] The accompanying drawings are provided to further illustrate the invention and form part of the specification. They are used together with the embodiments of the invention to explain the invention and do not constitute a limitation thereof.
[0027] Figure 1 This is a schematic diagram of the overall structure of the present invention;
[0028] Figure 2 This is a schematic internal cross-sectional view of the present invention;
[0029] Figure 3 This is a partial schematic diagram of the sliding door when it is closed with the doorway of the box.
[0030] Figure 4This is a partial schematic diagram of the sliding door separating from the doorway of the housing;
[0031] Figure 5 for Figure 3 Schematic diagram showing the location of the sliding door and the doorway of the housing;
[0032] Figure 6 for Figure 4 Schematic diagram showing the location of the sliding door and the doorway of the housing;
[0033] Figure 7 This is a schematic diagram of an embodiment of the lateral positioning component;
[0034] Figure 8 for Figure 7 Installation diagram of the rotating base and support ring;
[0035] Figure 9 This is a schematic diagram showing the installation of the transverse spring slide bar, the fixing ring, and the clamping block;
[0036] Figure 10 This is a schematic diagram showing the vertical positioning component sealing the test tube opening during operation.
[0037] Figure 11 for Figure 10 Enlarged view of the structure of part A in the middle;
[0038] Figure 12 This is a schematic diagram of Embodiment 2 of the lateral positioning component;
[0039] Figure 13 for Figure 12 A schematic diagram of the lateral positioning component in the moving door when it closes with the doorway of the box;
[0040] Figure 14 for Figure 12 Cross-sectional view of the fixed ring and the arc-shaped annular component;
[0041] Figure 15 This is a schematic diagram of the structure of a wedge-shaped extrusion part;
[0042] Figure 16 for Figure 14 Diagram showing the fit between the transverse spring slide bar, the arc-shaped ring component, and the clamping block;
[0043] Figure 17 for Figure 16 Enlarged view of the structure of part B in the middle section.
[0044] In the diagram: 1. Box body, 2. Doorway, 3. Temperature control component, 31. Pipe, 32. Heater, 33. Fan, 34. Air duct, 4. Bracket, 41. Slide plate, 42. Stand, 5. Telescopic frame, 51. Slide plate, 52. Perforated plate, 53. Stand plate, 6. Sliding door, 61. Base, 62. Sealing plate, 7. Telescopic drive component, 71. First motor, 72. Drive gear disc, 73. Lead screw, 74. Driven gear, 8. Lateral positioning component, 81. Vertical spring slide rod, 82. Support ring, 83. Rotating seat, 831. Grooved rotating plate, 832. Second motor, 833. Square sliding sleeve rod, 84. Vertical rod, 8 5. Fixed ring, 86. Horizontal spring slide bar, 87. Clamping block, 88. Wedge-shaped extrusion piece, 880. Wedge-shaped surface, 89. Arc-shaped ring piece, 890. Arc surface, 891. Fixed plate, 860. Slide tube, 861. Frustum block, 862. First spring, 863. Crossbar, 864. Second spring, 865. Limiting ring, 9. Vertical positioning assembly, 91. First movable plate, 92. Second movable plate, 93. First torsion spring shaft, 94. Second torsion spring shaft, 95. Flexible sealing plug, 96. First gear, 97. Second gear, 98. Bevel gear set, 99. Rotating shaft, 910. Worm gear, 911. Worm wheel, 10. Test tube. Detailed Implementation
[0045] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention;
[0046] Reference Figure 1-11 A gene testing kit for childhood asthma includes a box body 1 with multiple door openings 2 around its perimeter. A support 4 is provided on the bottom plate inside the box body 1. A temperature control component 3 is provided on the support 4 and the top plate of the box body 1. Multiple telescopic frames 5 are connected to the support 4 around its perimeter via telescopic drive components 7. Each telescopic frame 5 is connected to a movable door 6. Each movable door 6 is provided with a horizontal positioning component 8 for positioning test tubes 10. A vertical positioning component 9 is provided on the support 4 near the telescopic frames 5 and the movable door 6. The test tubes 10 are horizontally positioned and rotated horizontally by the horizontal positioning component 8, and vertically positioned and sealed by the vertical positioning component 9.
[0047] The temperature control component 3 includes a pipe 31 fixed inside the box 1. A heater 32 and a fan 33 are installed inside the pipe 31. An air vent is located at the top of the box 1 corresponding to the top of the pipe 31. Multiple air ducts 34 are connected to the bottom of the pipe 31. An air outlet is located at the end of each air duct 34 away from the pipe 31, and the air outlet corresponds to the sliding door 6 and the test tube 10. The temperature control component 3 also includes a temperature sensor and a controller. The temperature sensor monitors the temperature inside the pipe 31 and the box 1, and the controller controls the start and stop of the heater 31 and the fan 33. The controller, temperature sensor, and heater 32 work together to adjust the temperature inside the box 1 and the pipe 31. During temperature adjustment, the fan 33 first draws outside air into the pipe 31, which then passes through the heater 32 to form a hot airflow. This hot airflow is then ejected into the box 1 through the air ducts 34. The temperature sensor detects the temperature inside the box 1 and feeds the data back to the controller, which then controls the start and stop of the heater 32 and the fan 33 based on the current temperature. Hot air is sprayed onto the positioned test tube 10, thereby providing a suitable preservation temperature for the sample stored inside the test tube 10.
[0048] The bracket 4 includes a central plate fixed on the bottom plate of the box 1. Multiple sliding plates 41 are installed radially outward from the center of the central plate. Each of the multiple sliding plates 41 is mounted with an upright 42 at the end away from the central plate. The end of the air duct 34 with an air outlet is connected to the side of the upright 42, and the air outlet of the air duct 34 corresponds to the test tube 10.
[0049] The telescopic frame 5 includes a slide plate 51 that is slidably installed with the slide plate 41. A perforated plate 52 is installed at one end of the slide plate 51 near the center plate. The other end of the slide plate 51 is connected and fixed to the movable door 6. A vertical plate 53 is installed upward at the end of the slide plate 51 near the movable door 6.
[0050] The telescopic drive assembly 7 includes an active gear disk 72 rotatably mounted on the top surface of the central plate. The central gear 72 is driven by a first motor 71, which is fixed on the bottom plate of the box body 1. It also includes a lead screw 73 mounted on the upper side of the slide plate 41 and rotatably mounted with the upright frame 42. The lead screw 72 is threadedly mounted to the thread hole plate 52. A driven gear 74 is mounted on one end of the lead screw 73 near the central plate, and the driven gear 74 meshes with the active gear disk 72.
[0051] The first motor 71 drives the active gear disk 72 to mesh with the driven gear 74 for transmission, and controls the threaded plate 52, the slide plate 51 and the movable door 6 to slide laterally relative to the box body 1 through the lead screw 73. The movable door 6 and the door opening 2 are sealed and connected or separated from each other.
[0052] In this embodiment, the active gear disk 72 simultaneously meshes with the driven gears 74 at the ends of multiple lead screws 73, thereby controlling the rotation of multiple lead screws 73. This allows multiple telescopic frames 5 and movable doors 6 to simultaneously close or separate from the doorway 2. When the movable door 6 separates from the doorway 2, the movable door 6 moves to the outside of the box 1. At this time, the test tube 10 can be placed in or removed from the transverse positioning component 8.
[0053] The movable door 6 includes a base 61 that slides and fits against the bottom plate of the box body 1. One side of the base 61 is connected to the slide plate 51 of the telescopic frame 5, and a sealing plate 62 is installed on the other side. The sealing plate 62 is sealed and fitted with the door opening 2. The lateral positioning component 8 is installed on the base 61 and is used to laterally position the test tube 10 and control the lateral rotation of the test tube 10.
[0054] The lateral positioning component 8 includes multiple vertical spring slide rods 81 fixed on the base 61. A support ring 82 is slidably mounted on the upper end of the multiple vertical spring slide rods 81. A rotating seat 83 is movably mounted at the center of the support ring 82. Multiple vertical rods 84 are fixed on the upper side of the support ring 82. A fixing ring 85 is mounted on the upper part of the vertical rods 84. A clamping block 87 is movably mounted on the inner side of the fixing ring 85 through a lateral spring slide rod 86. The clamping block 87 is located on the side of the fixing ring 85 near the center and has a uniform diameter arc surface at the lower part. The upper part has a variable diameter arc surface with the diameter gradually increasing from top to bottom. The surface of the uniform diameter arc surface is provided with anti-slip texture.
[0055] When the test tube 10 is placed into the horizontal positioning component 8, the clamp 87 does not contact the outer wall of the test tube 10 but has a gap. When the bottom of the test tube 10 descends to the center of the top surface of the rotating seat 83, the rotating seat 83 provides vertical support for the test tube 10.
[0056] The rotating seat 83 includes a grooved rotating plate 831 rotatably mounted to the support ring 82. The top surface of the grooved rotating plate 831 is provided with a groove that matches the bottom of the test tube 10. The bottom surface of the grooved rotating plate 831 is connected to the drive shaft of the second motor 832 through a square sliding sleeve rod 833. The square sliding sleeve rod 833 includes a square sleeve and a square sub-rod that are slidably mounted to each other. The lower end of the square sleeve is connected to the drive shaft of the second motor 832, and the upper end of the square sub-rod is fixedly connected to the bottom surface of the grooved rotating plate 831.
[0057] When the test tube 10 moves down to the rotating seat 83, the bottom of the test tube 10 is located in the groove at the center of the top surface of the rotating seat 83, and the groove matches the bottom of the test tube 10.
[0058] In addition, a wedge-shaped extruder 88 is installed on the bottom plate of the box body 1 at the position corresponding to each support ring 82. The wedge-shaped extruder 88 has a downwardly oriented wedge surface 880 at one end near the support ring 82. The lower surface of the wedge-shaped extruder 88 and the wedge surface 880 are in separable sliding contact with the upper surface of the support ring 82.
[0059] The inner wall of the sealing plate 62 and the outer side of each fixing ring 85 are fixed with an arc-shaped annular part 89 by a fixing plate 891. An arc surface 890 is opened on the inner side of the upper end of the arc-shaped annular part 89.
[0060] The transverse spring slide bar 86 includes a slide tube 860 that is slidably mounted transversely to the fixing ring 85. A crossbar 863 is slidably mounted on one end of the slide tube 860 near the clamping block 87 via a limiting ring 865. The end of the crossbar 863 away from the slide tube 860 is fixed to the outer surface of the clamping block 87. The end of the slide tube 860 away from the clamping block 87 extends to the outside of the fixing ring 85 and is fixed with a frustum block 861. The frustum block 861 slides in contact with the arc surface 890 at the upper end of the arc-shaped ring 89. A first spring 862 is sleeved on one end of the slide tube 860 extending to the outside of the fixing ring 85. A second spring 864 is sleeved on the crossbar 863. One end of the second spring 864 is fixed to the end of the slide tube 860, and the other end is fixed to the outer surface of the clamping block 87.
[0061] As the sliding door 6 is moved laterally by the sliding plate 51 and gradually aligns with the door opening 2, the wedge-shaped extruder 88 first slides against the upper surface of the support ring 82 using its wedge-shaped surface 880. At this time, guided by the wedge-shaped surface 880, the support ring 82 moves down and compresses the vertical spring slide rod 81. Then, the upper surface of the support ring 82 slides against the lower surface of the wedge-shaped extruder 88. The support ring 82 continues to move towards the inside of the box 1 and stops when the sealing plate 62 of the sliding door 6 closes with the door opening 2.
[0062] When the support ring 82 is guided downward by the wedge surface 880, the vertical rod 84 controls the fixed ring 85 and the horizontal spring slide rod 86 to move downward. During the downward movement, the frustum block 861 in the horizontal spring slide rod 86 slides into contact with the arc surface 890 at the upper end of the arc-shaped ring 89. Under the guidance of the arc surface 890, the frustum block 861 and the slide tube 860 slide laterally relative to the fixed ring 85 and compress the first spring 862. At the same time, the slide tube 860 uses the second spring 865 to push the crossbar 863 and the clamping block 87 laterally, so that the clamping block 87 can gradually contact and clamp the test tube 10. Finally, when the sealing plate 62 of the moving door 6 closes with the door opening 2, the frustum block 861, the slide tube 860, and the second spring 865 can control the clamping block 87 to clamp and position the test tube 10 stably.
[0063] Conversely, when the sealing plate 62 separates from the door opening, the wedge-shaped extruder 88 gradually separates from the support ring 82, causing the fixing ring 85 to move upward and reset, thereby removing the contact and extrusion force between the frustum block 861 and the arc surface 890, causing the first spring 862 and the second spring 864 to extend, and causing the slide tube 860 to pull the limiting ring 865, the crossbar 863 and the clamping block 87 to reset, thereby removing the clamping block 87 from the test tube 10;
[0064] The above operation process makes it very convenient and smooth to put the test tube 10 into and take it out of the horizontal positioning component 8, and can achieve a stable horizontal positioning effect after it is put in.
[0065] In addition, the rotation of the rotating seat 83 also has a lateral rotation effect, which enables the temperature control component 3 to heat the test tube 10 fully and evenly.
[0066] The vertical positioning component 9 includes a first movable plate 91 and a second movable plate 92 movably disposed on the upper end of the upright 42, with the second movable plate 92 located above the first movable plate 91. The first movable plate 91 is movably installed to the upper end of the upright 42 via a first torsion spring shaft 93. The lower end of the first movable plate 91 extends between the upright 42 and the upright plate 53 and slides in contact with the side of the upright plate 53. The upper end of the first movable plate 91 extends to the other side of the upright 42 and slides in contact with the lower surface of one end of the second movable plate 92. 2. The second movable plate 92 is movably installed on the upper end of the support frame 42 via the second torsion spring shaft 94. One end of the second movable plate 92 extends above the transverse positioning component 8 and is located on the side of the support frame 42 near the vertical plate 53. The other end extends to the other side of the support frame 41 away from the transverse positioning component 8 and the vertical plate 53. A flexible sealing plug 95 is installed on the bottom surface of the second movable plate 92 near the upper end of the transverse positioning component 8. The flexible sealing plug 95 slides and seals with the inside of the tube opening of the test tube 10. The flexible sealing plug 95 is formed by stacking multiple rubber sheets along the axial direction of the shaft.
[0067] After the test tube 10 is placed by the horizontal positioning component 8, the telescopic drive component 7 can control the moving door 6, the test tube 10, and the horizontal positioning component 8 to move as a whole towards the inside of the box 1. The movement stops after the sealing plate 62 of the moving door 6 closes with the door opening 2; and during the closing process, as the telescopic frame 5 moves, the upright plate 53 can gradually move towards the lower end of the first movable plate 91 ( Figure 10 The sliding compression is achieved at the middle left end. The first movable door 91, in cooperation with the first torsion spring shaft 93, utilizes its upper end ( Figure 10 The right end of the middle plate is opposite one end of the second movable plate 92. Figure 10 The right end of the middle plate slides and presses, causing the other end of the second movable plate 92 ( Figure 10The left end of the tube 10 swings towards the opening of the test tube 10 with the help of the second torsion spring shaft 94, and gradually pushes the flexible sealing plug 95 into the opening of the test tube 10, thereby forming a seal on the opening of the test tube 10. In addition, the rotating seat 83 in the horizontal positioning component 8 and the vertical spring slide rod 81 achieve vertical positioning of the test tube 10 as a whole. At this point, the storage and positioning of the test tube 10 is completed. During the subsequent transportation process, the horizontal and vertical vibrations generated can be reduced, thereby preventing the test tube 10 from breaking and the internal sample from spilling out.
[0068] The flexible sealing plug 95 is rotatably mounted to the second movable plate 92 via a shaft. The top surface of the second movable plate 92 and the upper end of the vertical plate 42 are jointly provided with a rotation control assembly. The rotation control assembly includes a rotating shaft 99 and a sub-shaft rotatably mounted on the top surface of the second movable plate 92. The rotating shaft 99 and the sub-shaft are meshed and driven by a bevel gear set 98. A worm 910 is installed at the end of the rotating shaft 99 away from the sub-shaft and the bevel gear set 98. A worm wheel 911 is installed at the upper end of the shaft of the flexible sealing plug 95. The worm 910 and the worm wheel 911 are meshed and driven.
[0069] The second gear 97 is installed at the end of the sub-shaft away from the bevel gear set 98, and the first gear 96 is fixed at the upper end of the support frame 42. The second gear 97 meshes with the first gear 96 and moves in a circular motion around the first gear 96.
[0070] When the second movable plate 92 rotates around the second torsion spring shaft 94, the second gear 97 meshes with the first gear 96 and moves in a circular motion around the first gear 96. The sub-shaft and rotating shaft 99 are linked by the bevel gear set 98, and the worm 910 and worm wheel 911 are meshed and driven. Finally, the flexible sealing plug 95, which is rotatably mounted on the shaft and the second movable plate 92, can rotate relative to the second movable plate 92. This makes it faster and smoother when entering or leaving the mouth of the test tube 10. When entering the mouth of the test tube 10, it can improve the sealing effect. When leaving, it can reduce the vertical pulling force on the test tube 10. This allows the lateral positioning component 8 to maintain a stable positioning effect on the test tube 10, which facilitates the rapid exit of the test tube 10 from the box 1. In addition, when the flexible sealing plug 95 rotates, the rotating seat 83 can be controlled to rotate in the opposite direction. That is, when the flexible sealing plug 95 rotates in the forward direction and gradually enters the mouth of the test tube 10, the rotating seat 83 rotates in the opposite direction. When the flexible sealing plug 95 rotates in the opposite direction and gradually leaves the mouth of the test tube 10, the rotating seat 83 rotates in the forward direction. The purpose is to further accelerate the speed at which the flexible sealing plug 95 enters or leaves the mouth of the test tube 10.
Claims
1. A gene detection kit for childhood asthma, comprising a housing (1), characterized in that, The box (1) has multiple door openings (2) around its perimeter. A support (4) is provided on the bottom plate inside the box (1). Multiple telescopic frames (5) are connected around the support (4) via telescopic drive components (7). Each telescopic frame (5) is connected to a movable door (6). Each movable door (6) is provided with a horizontal positioning component (8) for positioning the test tube (10). A vertical positioning component (9) is provided on the side of the support (4) near the telescopic frame (5) and the movable door (6). The test tube (10) is horizontally positioned and rotated horizontally by the horizontal positioning component (8). The test tube (10) is vertically positioned and sealed by the vertical positioning component (9). The bracket (4) includes a central plate fixed on the bottom plate of the box (1). The central plate has multiple sliding plates (41) installed radially outward from its own center. Each of the multiple sliding plates (41) has an upright frame (42) installed upward at the end away from the central plate. The telescopic frame (5) includes a slide plate (51) that is slidably installed with the slide plate (41). A perforated plate (52) is installed at one end of the slide plate (51) near the center plate. The other end of the slide plate (51) is connected and fixed to the movable door (6). A vertical plate (53) is installed upward at one end of the slide plate (51) near the movable door (6). The telescopic drive assembly (7) includes an active gear disk (72) rotatably mounted on the top surface of the center plate. The active gear disk (72) is driven by a first motor (71). The first motor (71) is fixed on the bottom plate of the box (1). It also includes a lead screw (73) mounted on the upper side of the slide plate (41) and rotatably mounted on the upright frame (42). The lead screw (73) is threadedly mounted on the thread hole plate (52). A driven gear (74) is mounted on one end of the lead screw (73) near the center plate, and the driven gear (74) meshes with the active gear disk (72). The first motor (71) drives the active gear disk (72) to mesh with the driven gear (74) for transmission, and controls the wire hole plate (52), the slide plate (51) and the moving door (6) to slide laterally relative to the box body (1) through the lead screw (73). The moving door (6) and the door opening (2) are sealed and connected or separated from each other. The movable door (6) includes a base (61) that slides and fits against the bottom plate of the box (1). One side of the base (61) is connected to the slide plate (51) of the telescopic frame (5), and a sealing plate (62) is installed on the other side. The sealing plate (62) is sealed and fitted with the door opening (2). The lateral positioning component (8) is installed on the base (61) for lateral positioning of the test tube (10) and for controlling the lateral rotation of the test tube (10). The lateral positioning component (8) includes multiple vertical spring slide rods (81) fixed on the base (61). The upper ends of the multiple vertical spring slide rods (81) are slidably mounted with a support ring (82). A rotating seat (83) is movably provided at the center of the support ring (82). Multiple vertical rods (84) are fixed on the upper side of the support ring (82). A fixing ring (85) is installed above the vertical rods (84). A clamping block (87) is movably mounted on the inner side of the fixing ring (85) through a lateral spring slide rod (86). The clamping block (87) is close to the center of the fixing ring (85) and its lower part is a constant diameter arc surface. Its upper part is a variable diameter arc surface with a diameter that gradually increases from top to bottom. The rotating seat (83) includes a grooved rotating plate (831) rotatably mounted to the support ring (82). The top surface of the grooved rotating plate (831) is provided with a groove that matches the bottom of the test tube (10). The bottom surface of the grooved rotating plate (831) is connected to the drive shaft of the second motor (832) through a square sliding sleeve (833). The square sliding sleeve (833) includes a square sleeve and a square sub-rod that are slidably mounted to each other. The lower end of the square sleeve is connected to the drive shaft of the second motor (832), and the upper end of the square sub-rod is fixedly connected to the bottom surface of the grooved rotating plate (831). On the bottom plate of the box body (1), a wedge-shaped extruder (88) is installed at the position corresponding to each support ring (82). The wedge-shaped extruder (88) has a downwardly oriented wedge-shaped surface (880) at one end near the support ring (82). The lower surface of the wedge-shaped extruder (88) and the wedge-shaped surface (880) are in separable sliding contact with the upper surface of the support ring (82). The inner wall of the sealing plate (62) and the outer side of each fixing ring (85) are fixed with an arc-shaped ring (89) by a fixing plate (891), and an arc surface (890) is opened on the inner side of the upper end of the arc-shaped ring (89). The transverse spring slide rod (86) includes a slide tube (860) that is slidably mounted transversely to the fixing ring (85). A crossbar (863) is slidably mounted on one end of the slide tube (860) near the clamping block (87) through a limiting ring (865). The end of the crossbar (863) away from the slide tube (860) is fixed to the outer surface of the clamping block (87). The end of the slide tube (860) away from the clamping block (87) extends to the outside of the fixing ring (85) and is fixed with a frustum block (861). The frustum block (861) slides in contact with the arc surface (890) at the upper end of the arc-shaped ring (89). A first spring (862) is sleeved on one end of the slide tube (860) extending to the outside of the fixing ring (85). A second spring (864) is sleeved on the crossbar (863). One end of the second spring (864) is fixed to the end of the slide tube (860), and the other end is fixed to the outer surface of the clamping block (87).
2. The childhood asthma gene detection kit according to claim 1, characterized in that, A temperature control component (3) is provided on the support (4) and the top plate of the box (1). The temperature control component (3) includes a pipe (31) fixed inside the box (1). A heater (32) and a fan (33) are installed inside the pipe (31). An air hole is opened at the top of the top plate of the box (1) corresponding to the top of the pipe (31). Multiple air ducts (34) are connected to the bottom of the pipe (31). An air outlet is provided at the end of the air duct (34) away from the pipe (31), and the air outlet corresponds to the sliding door (6) and the test tube (10).
3. The childhood asthma gene detection kit according to claim 1, characterized in that, The vertical positioning component (9) includes a first movable plate (91) and a second movable plate (92) movably disposed on the upper end of the upright (42), with the second movable plate (92) located above the first movable plate (91). The first movable plate (91) is movably installed on the upper end of the upright (42) via a first torsion spring shaft (93). The lower end of the first movable plate (91) extends between the upright (42) and the upright plate (53) and slides in contact with the side of the upright plate (53). The upper end of the first movable plate (91) extends to the other side of the upright (42) and is in contact with the lower surface of one end of the second movable plate (92). In sliding contact, the second movable plate (92) is movably installed on the upper end of the stand (42) via the second torsion spring shaft (94). One end of the second movable plate (92) extends above the transverse positioning component (8) and is located on the side of the stand (42) near the stand plate (53), while the other end extends to the other side of the stand (42) away from the transverse positioning component (8) and the stand plate (53). A flexible sealing plug (95) is installed on the bottom surface of the second movable plate (92) near the transverse positioning component (8), and the flexible sealing plug (95) slides and seals with the inside of the tube opening of the test tube (10).
4. The childhood asthma gene detection kit according to claim 3, characterized in that, The flexible sealing plug (95) is rotatably mounted to the second movable plate (92) via a shaft. The top surface of the second movable plate (92) and the upper end of the vertical plate (53) are jointly provided with a rotation control assembly. The rotation control assembly includes a rotating shaft (99) and a sub-shaft rotatably mounted on the top surface of the second movable plate (92). The rotating shaft (99) and the sub-shaft are meshed and driven by a bevel gear set (98). A worm gear (910) is installed at the end of the rotating shaft (99) away from the sub-shaft and the bevel gear set (98). A worm wheel is installed at the upper end of the shaft of the flexible sealing plug (95). The worm gear (910) and the worm wheel (911) mesh and drive each other. The second gear (97) is installed at the end of the sub-shaft away from the bevel gear set (98), and the first gear (96) is fixed at the upper end of the stand (42). The second gear (97) meshes with the first gear (96) and makes a circular motion around the first gear (96).