Modular Fluid Chip and Fluid Flow System Comprising the Modular Fluid Chip
Through the design of the modular fluid chip, the problem that existing microfluidic devices are difficult to repair after functional changes or damage is solved, the flexibility and scalability of the fluid flow system are realized, and the accuracy and maintainability of the experimental data are improved.
Patent Information
- Application Number
- CN202310404698.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Priority Date
- 2019-07-23
- Filing Date
- 2019-07-25
- Publication Date
- 2025-05-27
- Estimated Expiration
- 2039-07-25
AI Technical Summary
Existing microfluidic devices are difficult to repair after functional changes or damage, and their structural expansion is limited, resulting in problems with experimental data accuracy and maintainability.
A modular fluid chip is designed to realize a fluid flow system of various structures by connecting multiple fluid chips of different functions without limitation in shape or size. The main body of the chip includes a core member and a connecting member that can be elastically deformed to open or close the flow passage.
The flexibility and scalability of the fluid flow system are achieved, and the damaged parts can be replaced as needed, reducing manufacturing and maintenance costs, and improving the accuracy of experimental data.
Smart Images

Figure CN116393185B_ABST
Abstract
Description
[0001] This application is a divisional application of the patent application with the application number 201980050280.8, the application date of July 25, 2019, and the invention title of "Modular Fluid Chip and Fluid Flow System Comprising the Modular Fluid Chip". Technical Field
[0002] The present disclosure relates to a modular fluid chip and a fluid flow system including the modular fluid chip, and more particularly, to a modular fluid chip of a fluid flow system capable of implementing various structures by connecting a plurality of fluid chips capable of performing different functions, and a fluid flow system including the modular fluid chip. Background Art
[0003] To overcome the disadvantages of existing diagnostic technologies, Lab-on-a-chip (LOC) technology has received extensive attention. Lab-on-a-chip technology is a representative example of the fusion technology of NT, IT, and BT, and refers to a technology that performs all sample pretreatment and analysis steps such as sample dilution, mixing, reaction, separation, and quantification on a single chip by using technologies such as MEMS and NEMS.
[0004] Microfluidic devices applying such Lab-on-a-chip technology analyze and diagnose the flow of a fluid sample flowing through a reaction channel or the reaction between a reagent and the fluid sample supplied to the reaction channel. In addition, such microfluidic devices are manufactured in the following form: a plurality of units required for analysis are provided on a small chip with a size of several square centimeters formed of glass, silicon, or plastic, so that various steps of processing and operation can be performed on a single chip.
[0005] Specifically, the microfluidic device is configured to include a chamber capable of capturing a small amount of fluid, a reaction channel through which the fluid can flow, a valve capable of controlling the fluid flow, and various functional units capable of performing preset functions by receiving the fluid.
[0006] However, since conventional microfluidic devices are manufactured to have functions associated with a plurality of microfluidic devices according to experimental purposes, even if one function changes or has a problem, the entire device should be newly manufactured. In addition, there are also limitations in that it is not easy to manage.
[0007] Moreover, once the microfluidic device is manufactured, it is difficult to change the design of the manufactured device, and the manufactured device is not compatible with other microfluidic devices, so that other experiments cannot be performed except for the set experiments.
[0008] In addition, conventional microfluidic devices are limited in the size and specifications that can be manufactured, making it infeasible to expand the structure of the microfluidic device. Therefore, there are limitations in obtaining accurate experimental data because it is necessary to predict the entire experimental result after only a part of the experiment is performed. Summary of the Invention
[0009] Technical Problem
[0010] The present disclosure is conceived to solve the above problems, and an object of the present disclosure is to provide a modular fluid chip and a fluid flow system including the modular fluid chip. The modular fluid chip can implement fluid flow systems of various structures by connecting a plurality of fluid chips that can perform different functions as needed, without limitations in shape or size. Thus, various accurate experimental data can be obtained, and when a specific part is deformed or damaged, only the corresponding fluid chip can be replaced.
[0011] The technical problems to be solved by the present disclosure are not limited to the above problems, and those skilled in the art can clearly understand other problems not mentioned from the following description.
[0012] Technical Solution
[0013] A modular fluid chip for solving the above problems according to a first embodiment of the present disclosure includes a main body configured to have at least one flow channel formed inside the main body and connected to another modular fluid chip to allow the at least one flow channel to communicate with a flow channel provided in the another modular fluid chip.
[0014] The main body may include: a core member in which at least one flow channel is formed; and at least one connection member provided in the core member to be coupled to the another modular fluid chip.
[0015] The connection member may be configured to be integrally provided with the core member or coupled to the core member and separable from the core member.
[0016] The connection member may be configured to open a flow channel provided inside the connection member when coupled to the another modular fluid chip and close the flow channel when separated from the another modular fluid chip.
[0017] The connection member may be formed of an elastic material and configured to open the flow channel by compressing axially and simultaneously expanding in a direction perpendicular to the axial direction when the connection member is axially pressured by the another modular fluid chip coupled to one side of the connection member, and configured to close the flow channel by elastic force recovery when the pressure is released.
[0018] On the inner surface of the connecting member, an opening and closing portion may be provided, which contacts or separates from each other according to the deformation of the connecting member, thereby closing and opening the flow channel.
[0019] In addition, the modular fluid chip according to the second embodiment of the present disclosure includes a main body having at least one flow channel formed inside the main body, wherein the at least one flow channel includes a first flow channel and a second flow channel having different heights.
[0020] The first flow channel may be formed at a position relatively lower than the second flow channel, and the first flow channel and the second flow channel may be configured to guide the fluid flowing therein in the horizontal direction.
[0021] The at least one flow channel may further include: a third flow channel configured to guide the flow of the fluid in the vertical direction; a chamber configured to store and stabilize the fluid introduced from one side thereof and discharge the fluid to the other side thereof; and a fourth flow channel formed at a position relatively lower than the position of the first flow channel or the chamber and configured to guide the fluid flowing therein in the horizontal direction.
[0022] The at least one flow channel may be configured to allow the fluid discharged from the chamber to pass through at least one of the first flow channel, the second flow channel, the third flow channel, and the fourth flow channel.
[0023] The main body may be provided with an air flow hole that allows the at least one flow channel to communicate with the external space.
[0024] The modular fluid chip may further include an opening and closing member configured to be attached to the main body and open and close the air flow hole.
[0025] The opening and closing member may be formed of a hydrophobic material capable of removing bubbles from the hydrophilic fluid flowing through the at least one flow channel, or may be formed of a fibrous structure coated with a hydrophobic material on the surface.
[0026] The opening and closing member formed of a hydrophobic material may be formed of one or more hydrophobic materials selected from the group consisting of Polytetrafluroethylene (PTFE), Polyethylene Terephtalate (PET), and Polyvinyl Chloride.
[0027] The opening and closing member may be formed of a hydrophilic material capable of removing air bubbles from the hydrophobic fluid flowing through at least one flow channel, or may be formed of a fibrous structure having a hydrophilic material coated on its surface.
[0028] The opening and closing member may include a hydrophobic material and a hydrophilic material.
[0029] The main body may be integrally formed by a 3D printing process, or may be formed in the form of a plurality of modules that are combined and separated from each other by an injection molding process.
[0030] In addition, a modular fluid chip according to a third embodiment of the present disclosure includes a main body having at least one flow channel formed inside the main body, wherein the main body includes: a core member including a plurality of first diversion channels for guiding the flow of fluid in a vertical direction; and a thin film member configured to be attached to an outer surface of the core member and allowing the plurality of first diversion channels to communicate with each other.
[0031] The thin film member may include: a first thin film layer attached to an outer surface of the core member and having at least one second diversion channel formed inside the first thin film layer, the at least one second diversion channel being connected to the plurality of first diversion channels to guide the flow of fluid in a horizontal direction; and a second thin film layer attached to an outer surface of the first thin film layer.
[0032] The core member may be integrally formed by a 3D printing process, or may be formed in the form of a plurality of modules that are combined and separated from each other by an injection molding process.
[0033] In addition, a fluid flow system according to an embodiment of the present disclosure includes: a first modular fluid chip capable of implementing a first function; and at least one second modular fluid chip capable of implementing a second function different from the first function and capable of being connected to the first modular fluid chip in at least one of a horizontal direction and a vertical direction.
[0034] Advantageous Effects
[0035] According to an embodiment of the present disclosure, a fluid chip capable of performing one function is formed in the form of a module, whereby fluid flow systems of various structures can be implemented as needed by connecting a plurality of fluid chips capable of performing different functions, without limitation in shape or size. Accordingly, various accurate experimental data can be obtained, and when a specific part is deformed or damaged, only the corresponding fluid chip can be replaced, thereby reducing manufacturing and maintenance costs.
[0036] In addition, the housing that can be connected to another modular fluid chip and the body in which channels are formed and selectively replaced in the housing are both formed in a modular shape. Therefore, it is feasible that, as needed, the position of a selected section and the shape of the channels can be easily changed in a fluid flow system. Thus, compared with a conventional fluid flow system, it is feasible to quickly change the experimental conditions, allowing various experiments to be carried out within a preset time period, and when a component is defective or damaged, it is possible to quickly replace only the housing or the body corresponding to that component.
[0037] In addition, when the modular fluid chip is connected to other modular fluid chips, the holes of the corresponding fluid chips are aligned and communicate with each other, and at the connection part of the modular fluid chip and other modular fluid chips, fluid connectors that are in close contact with each other and form an interface are provided. Therefore, fluid leakage at the connection part during fluid flow is prevented, and the change in fluid pressure is minimized. In addition, the composition of the fluid or the shape of the droplets can be maintained. BRIEF DESCRIPTION OF THE DRAWINGS
[0038] Figure 1 is a perspective view of a fluid flow system in which modular fluid chips according to embodiments of the present disclosure are connected in a horizontal direction.
[0039] Figure 2 is a plan view of a modular fluid chip according to embodiments of the present disclosure.
[0040] Figure 3 is a view schematically showing the process of opening and closing a connection member of a modular fluid chip according to embodiments of the present disclosure.
[0041] Figures 4 to 8 is a view schematically showing the flow channels of a modular fluid chip according to embodiments of the present disclosure.
[0042] Figure 9 and Figure 10 are views each schematically showing modified embodiments of the body of a modular fluid chip according to embodiments of the present disclosure.
[0043] Figure 11 is a perspective view of a fluid flow system in which modular fluid chips according to embodiments of the present disclosure are connected in a horizontal direction.
[0044] Figure 12 is a perspective view showing a state in which the lid of a modular fluid chip according to embodiments of the present disclosure is separated.
[0045] Figure 13 is Figure 12 exploded perspective view of.
[0046] Figures 14 to 16 is a view schematically showing various embodiments of channels formed in a body of a modular fluid chip according to an embodiment of the present disclosure.
[0047] Figure 17 is a plan view of a modular fluid chip according to an embodiment of the present disclosure.
[0048] Figure 18 is a view showing Figure 17 cross-sections of portions "A", "B", and "C".
[0049] Figures 19 to 20 are exploded perspective views each showing a modified embodiment of a magnetic coupling unit in a modular fluid chip according to an embodiment of the present disclosure.
[0050] Figure 21a and Figure 21b are perspective views each showing a fluid flow system vertically connected in a modular fluid chip according to an embodiment of the present disclosure.
[0051] Figure 22a , Figure 22b , Figure 22c and Figure 22d are perspective views each showing a modular fluid chip according to an embodiment of the present disclosure to which a vertical connection structure is applied.
[0052] Figure 23a , Figure 23b , Figure 23c and Figure 23d is Figure 22a , Figure 22b , Figure 22c and Figure 22d exploded perspective view.
[0053] Figure 24a is a perspective view showing a state in which a magnetic coupling unit is mounted on the outside of a lid in Figure 22b , Figure 24b is a perspective view showing a state in which a magnetic coupling unit is further mounted in a housing in Figure 22c .
[0054] Figure 25a is a schematic cross-sectional view showing a state in which a modular fluid chip is horizontally connected according to an embodiment of the present disclosure, Figure 25b and Figure 25c is a schematic cross-sectional view showing a state in which a modular fluid chip is vertically connected.
[0055] Figures 26 to 30 are views each schematically showing a state in which a coupling structure capable of physically coupling to a modular fluid chip according to an embodiment of the present disclosure is applied.
[0056] Figure 31 is an exploded perspective view showing the state of applying an imaging component and a light source to a modular fluid chip according to an embodiment of the present disclosure.
[0057] Figure 32 is an exploded perspective view showing the state of applying a temperature controller to a modular fluid chip according to an embodiment of the present disclosure.
[0058] Figure 33 is a perspective view showing the state of applying a fluid connector to a modular fluid chip according to an embodiment of the present disclosure.
[0059] Figure 34 is Figure 33 an exploded perspective view of
[0060] Figure 35 is a perspective view showing the state of a modular fluid chip connected to other modular fluid chips according to an embodiment of the present disclosure.
[0061] Figure 36 is a cross-sectional view taken along line Figure 35 A'-A' of
[0062] Figures 37 to 42 is a view showing the state of applying various embodiments of a fluid connector to a modular fluid chip according to an embodiment of the present disclosure.
[0063] Figure 43 is a perspective view schematically showing the state of a sensor mounted in a modular fluid chip according to an embodiment of the present disclosure. Detailed Description
[0064] Hereinafter, various embodiments will be described in more detail with reference to the accompanying drawings. The embodiments can be variously modified. Specific embodiments may be described in the drawings and specifically explained in the detailed description. However, the specific embodiments disclosed in the drawings are only intended to facilitate the understanding of various embodiments. Therefore, this is not intended to limit the technical concept to the specific embodiments disclosed in the drawings, and this should be understood to include all equivalent solutions or alternatives included in the spirit and scope of the present invention.
[0065] Terms such as first or second may be used to describe various components, but the components should not be limited by these terms. These terms are only used to distinguish one component from another component.
[0066] In this specification, it should be understood that the terms "comprising" or "having" indicate the presence of the features, numbers, steps, operations, components, parts, or combinations thereof described in this specification, but do not exclude the possibility of the pre-existence or addition of one or more other features, numbers, steps, operations, components, parts, or combinations thereof. When a component is referred to as being "connected" or "coupled" to another component, the component can be directly connected to or coupled to the other component, but it should be understood that other components may exist therebetween. On the other hand, when a component is referred to as being "directly connected" or "directly coupled" to another component, it should be understood that no other components exist therebetween.
[0067] Meanwhile, the "module" or "unit, part, or portion" used in the specification for a component performs at least one function or operation. And, the "module" or "unit, part, or portion" can perform the function or operation by hardware, software, or a combination of hardware and software. Additionally, multiple "modules" or multiple "units, parts, or portions" other than those that should be executed in specific hardware or by at least one processor can be integrated into at least one module. Unless the context clearly dictates the contrary, the singular expressions used herein include the plural expressions.
[0068] In addition, in the description of the present disclosure, when it is determined that a detailed description of related known technologies may unnecessarily obscure the gist of the present disclosure, the detailed description thereof is abbreviated or omitted.
[0069] Referring to Figure 1 and Figure 11 , the modular fluid chip 1 according to an embodiment of the present disclosure (hereinafter referred to as "modular fluid chip 1") is formed in the form of a module capable of performing one function and is connected to other modular fluid chips 2 to implement fluid flow systems 1000 of various structures.
[0070] The fluid flow system 1000 implemented by the modular fluid chip 1 can perform analysis / detection processes from fluids such as liquid samples including body fluids, blood, saliva, and skin cells, such as sample collection, sample chopping, extraction of substances such as genes or proteins from the collected samples, filtration, mixing, storage, valves, amplification using polymerase chain reaction including RT-PCR, antigen-antibody reaction, affinity chromatography, and inductive sensing, electrochemical sensing, capacitive inductive sensing, and optical sensing with or without fluorescent materials. However, the fluid flow system 1000 implemented by the modular fluid chip 1 is not limited to having the above functions and can perform various functions for fluid analysis and diagnosis. For example, in this embodiment, the modular fluid chips 1 and 2 are shown to perform functions for fluid movement, but the fluid flow system 1000 can be configured to allow a series of processes, such as the following: after introducing the fluid therein and chopping and filtering the cells in the fluid, amplifying the genes, and then attaching a fluorescent substance to the amplified genes to be observed.
[0071] In addition, the fluid flow system 1000 implemented by the modular fluid chip 1 can implement factory-on-a-chip technology by connecting to another fluid flow system 1000. Thus, fluid analysis and diagnosis of different fluids can be performed simultaneously in the corresponding fluid flow system 1000, and all fluid-related experiments (such as chemical reactions and material synthesis, etc.) that can be performed using the fluid flow system 1000 can be performed simultaneously by multiple fluid flow systems 1000.
[0072] In addition, the modular fluid chip 1 can be connected to other modular fluid chips 2 in the horizontal direction (X-axis direction and Y-axis direction) to implement one fluid flow system 1000.
[0073] More specifically, the modular fluid chip 1 can be connected to other modular fluid chips 2 in the X-axis direction and Y-axis direction indicating the horizontal direction in the drawings, thereby implementing one fluid flow system 1000 including multiple fluid flow and analysis sections. Therefore, the fluid can move freely in the X-axis direction and Y-axis direction. For example, the number of other modular fluid chips 2 that can be connected in the X-axis direction and Y-axis direction around the modular fluid chip 1 can be 1 to 10,000.
[0074] The modular fluid chip 1 according to various embodiments of the present disclosure will be described in more detail.
[0075] Referring to Figure 1 and Figure 2 According to a first embodiment of the present disclosure, the modular fluid chip 1 includes a body 11.
[0076] The main body 11 is formed in the form of a module capable of performing a function and is accommodated in a housing 12 configured to surround the main body 11, which will be described later. The main body 11 can be selectively replaced in the housing 12 as needed.
[0077] In addition, a flow channel 112 is formed in the main body 11 to guide the flow of fluid.
[0078] The flow channel 112 can guide the flow of fluid in at least one of the X-axis direction and the Y-axis direction. However, the flow channel 12 is not limited thereto and can be configured to guide the flow of fluid in various directions and perform a preset function on the flowing fluid. For example, the flow channel 112 can perform various functions such as fluid mixing or distribution, as well as guiding the flow of fluid.
[0079] In addition, the flow channel 112 can be formed in a shape corresponding to the flow channel 11ba (refer to Figure 3 ) provided in the connection member 11b, which will be described later. Therefore, the flow channel 112 can prevent the phenomenon of unstable fluid flow or increased fluid pressure between the core member 11a and the connection member 11b during fluid flow. For example, the cross-section of the flow channel 112 can have a circular, polygonal, or elliptical shape. However, the shape of the flow channel 112 is not limited thereto and can be formed in various ways within the limit where the width w is equal to or greater than 10 nm and equal to or less than 1 Cm.
[0080] Here, the fact that the flow channel 112 and the flow channel 11ba provided in the connection member 11b have corresponding shapes and sizes and form a linear fluid path relative to each other can allow for a predictable flow rate when the fluid moves from one module to another. In some conventional microfluidic flow devices, the fluid is transported through tubes. In the case of a device using tubes, a difference in channel width occurs at the part where the tube and the device are connected to each other, or spaces may be generated in the channel, resulting in vortices in the fluid. Such vortices not only cause a rapid change in the flow rate but also may deform the droplet shape. In addition, it may cause a physical impact on the substances in the fluid or interrupt the movement of the substances. Therefore, the fact that the flow channel 112 of the core member 11a and the flow channel 11ba of the connection member 11b have the same width and are arranged in a straight line can allow for a stable flow rate of the fluid and a stable movement of the substances, in addition to simply ensuring the function of connecting between the modules.
[0081] Here, the flow channel 112 can be formed in various shapes such as a quantitative chamber, a gene extraction chamber, a waste chamber, a mixing chamber, a buffer chamber, a valve, etc. to perform various functions.
[0082] For example, refer toFigures 14 to 16 , inside the main body 11, at least one of the following flow channels can be formed: a straight flow channel 112 ( Figure 14 in (a), (b) of Figure 14 ), a streamlined flow channel 112 ( Figure 14 in (c), (d), (e) of Figure 15 ), a flow channel 112 having at least one well ( Figure 15 in (f), (g), (h) of Figure 15 ), a flow channel 112 having a valve ( Figure 16 in (a), (b), (c), (d), (e) of Figure 16 ), a flow channel 112 having at least one branch ( Figure 15 in (f), (g) of Figure 15 ), a cross-shaped flow channel 112 ( Figure 16 in (h), Figure 16 in (a)), a Y-shaped flow channel 112 ( Figure 16 in (b)), a fluid channel having a sensor (not shown), a fluid channel having an electrical output unit (not shown), and a fluid channel having an optical output unit (not shown). However, the flow channel 112 is not necessarily limited to this, and can be changed into various structures and shapes for application. In addition, the flow channel 112 can be formed by combining the above flow channels.
[0083] In addition, a coating can be further formed on the flow channel 112.
[0084] More specifically, a coating of a hydrophobic or hydrophilic material can be further formed on the flow channel 112. Here, the above types of coatings can be selectively applied to the flow channel 112 according to the type of fluid, thereby improving the fluid flow performance. However, the coating does not have to be formed only on the flow channel 112, and if necessary, the coating can be further formed on various functional units such as a metering chamber, a gene extraction chamber, a waste chamber, a mixing chamber, a buffer chamber, a valve, etc.
[0085] Meanwhile, referring to Figure 1 , another modular fluid chip 2 connected to the modular fluid chip 1 can include a main body 11 capable of performing a function different from that of the main body 11 of the modular fluid chip 1.
[0086] That is, different types of flow channels 112 can be formed in the main body 11 of the modular fluid chip 1 and the main body 11 of another modular fluid chip 2.
[0087] Accordingly, a plurality of modular fluid chips 1 and 2 connected to each other to implement a fluid flow system 1000 can perform different functions on the fluid flowing therethrough. Here, each of the plurality of modular fluid chips 1 and 2 connected to each other can be formed to perform only one function. For example, when one fluid chip 1 has a Y-shaped flow channel 112 and performs a mixing function, other fluid chips 2 connected to the fluid chip 1 can include flow channels 112 of a type different from the above-mentioned Y-shaped flow channel 112 and perform functions different from those of the fluid chip 1.
[0088] Moreover, the main body 11 is connected to other modular fluid chips 2 and allows at least one flow channel 112 of the main body 11 to communicate with the flow channels 112 provided in the other modular fluid chips 2.
[0089] Referring to Figure 1 and Figure 2 , the main body 11 may include a core member 11a and at least one connecting member 11b provided in the core member 11a.
[0090] The above-mentioned at least one flow channel 112 is formed in the core member 11a, and the core member 11a can be connected to other modular fluid chips 2 through the connecting member 11b. Here, the core member 11a may be provided with a coupling groove that communicates with the flow channel 112, and a part of the connecting member 11b is inserted into the coupling groove. Accordingly, the connecting member 11b can communicate with the flow channel 112 provided in the core member 11a through the coupling groove. In addition, when the core member 11a is connected to other modular fluid chips 2 through the connecting member 11b, the flow channels 112 provided in the core member 11a and the flow channels 11ba provided in the connecting member 11b can be aligned and communicate with the flow channels 112 provided in the other modular fluid chips 2.
[0091] Moreover, the core member 11a can be formed into a shape corresponding to the inner surface of the housing 12 having an accommodation space formed therein, and the core member 11a can be formed to have the same height as the housing 12. Preferably, when the core member 11a is coupled to the housing 12, the core member 11a can be formed in a polyhedron structure so that the core member 11a can be accurately set in a set position.
[0092] Further, techniques such as MEMS, 3D printing, injection molding, CNC machining, imprinting, and polymer casting can be used to fabricate the core member 11a. Here, the core member 11a can be formed integrally or partially with transparency such that the flow of fluid flowing into the interior from the exterior of the core member 11a can be visually confirmed. For example, the core member 11a can be formed of at least one of amorphous materials such as glass, wood, polymer resins, metals, and elastomers or can be formed by a combination thereof.
[0093] The connection member 11b can be disposed in the core member 11a and can be formed into a structure capable of being coupled to other modular fluid chips 2.
[0094] The connection member 11b is connected to the connection member 11b provided in other modular fluid chips 2 such that at least one flow channel 112 provided in the modular fluid chip 1 can communicate with the flow channel 112 provided in other modular fluid chips 2.
[0095] The connection member 11b is formed into a tubular shape having a flow channel 11ba therein and can be detachably mounted on the outer surface of the core member 11a to be described later. Here, a coupling groove can be formed in the outer surface of the core member 11a, which communicates with the flow channel 112 provided in the core member 11a, and a part of the connection member 11b is inserted into the coupling groove. Thus, when the connection member 11b is inserted into the coupling groove, the flow channel 11ba provided in the connection member 11b can be aligned with the flow channel 112 provided in the core member 11a to communicate therewith. For example, the coupling groove can be formed to correspond to the shape of the outer surface of the connection member 11b.
[0096] In addition, the connection member 11b can be received in a housing 12 to be described later and supported by the housing 12. Here, the housing 12 can have a receiving groove corresponding to and supporting the outer surface of the connection member 11b.
[0097] In addition, the connection member 11b can be configured to form an interface at the contact portion when contacting the core member 11a and another connection member 11b.
[0098] More specifically, the connection member 11b can be formed of an elastic material capable of elastic deformation and forms an interface at the contact portion when contacting the core member 11a and another connection member 11b. Here, an adhesive layer can be provided on one surface and the other surface of the connection member 11b.
[0099] Accordingly, one side of the connection member 11b is in close contact with the core member 11a to form an interface, and the other side of the connection member 11b is in close contact with the connection member 11b provided in the other modular fluid chip 2 to form an interface, thereby completely blocking fluid leakage.
[0100] For example, the connection member 11b may be formed of an elastomer material. More specifically, the connection member 11b may be formed of at least one of a polymer resin, an amorphous material, and a metal, and may include at least one of chlorinated polyethylene, dimethyl ethylene propylene, silicone rubber, acrylic resin, amide resin, epoxy resin, phenolic resin, polyester resin, polyethylene resin, ethylene propylene rubber, polyvinyl butyral resin, polyurethane resin, and nitrile rubber. However, the connection member 11b is not limited thereto, and may be changed into various shapes or various materials and thus applied under the condition of being able to perform the same function.
[0101] In addition, the connection member 11b may be provided integrally with the core member 11a, or may be coupled to the core member 11a and separable from the core member 11a.
[0102] That is to say, the connection member 11b may be integrally provided on the outer surface of the core member 11a by double injection molding, or may be separately manufactured from the core member 11a and coupled to the core member 11a. Here, when the connection member 11b is provided integrally with the core member 11a, the connection member 11b may form an interface only on one side thereof.
[0103] In addition, the connection member 11b may directly connect the modular fluid chip 1 and the other modular fluid chip 2.
[0104] More specifically, the connection member 11b coupled to the core member 11a of the modular fluid chip 1 does not pass through the connection member 11b provided in the other modular fluid chip 2, and may be directly coupled to the core member 11a of the other modular fluid chip 2.
[0105] Accordingly, one side of the connection member 11b is in close contact with the core member 11a of the modular fluid chip 1 to form an interface, and the other side of the connection member 11b is in close contact with the core member 11a of the other modular fluid chip 2 to form an interface, thereby minimizing fluid leakage points.
[0106] In addition, the connection member 11b may be configured to restrict movement in the X-axis direction and the Y-axis direction when being received in the housing 12.
[0107] More specifically, the connection member 11b may include a flange portion (not shown) that radially protrudes from the outer surface of the connection member 11b and is supported on the inner surface of the housing 12. Here, the housing 12 may be provided with a flange receiving groove (not shown) for receiving and supporting the flange portion, thereby restricting the movement of the connection member 11b.
[0108] Therefore, even when the modular fluid chip 1 is separated from the other modular fluid chip 2, the flange portion can be supported on the inner surface of the housing 12, thereby fixing the connection member 11b in a determined position.
[0109] In addition, the connection member 11b may be formed into a structure that can minimize deformation in the axial direction when coupled to the connection member 11b provided in the other modular fluid chip 2.
[0110] More specifically, the connection member 11b may include a plurality of bodies formed of different materials.
[0111] For example, the plurality of bodies having different materials may include a first body (not shown) and a second body (not shown). The first body (not shown) has a hollow tube shape so as to communicate with the flow channel 112 provided in the core member 11a, and the second body (not shown) is mounted on the outer surface of the first body and is formed of a material having a higher hardness than the first body.
[0112] Therefore, even when the modular fluid chip 1 and the other modular fluid chip 2 are coupled to each other and a load is applied to the connection member 11b in the axial direction, the deformation of the first body can be minimized by the second body. As a result, the deformation of the flow channel provided in the connection member 11b can be minimized, allowing the fluid to flow stably through the flow channel.
[0113] In addition, inclined surfaces may be formed at both ends of the connection member 11b.
[0114] Therefore, when the connection member 11b is inserted into the coupling groove of the core member 11a, it is possible to prevent the edge of the end of the connection member 11b provided with the inclined surface from contacting the inner surface of the core member 11a. Thus, the insertion of the connection member 11b can be easily performed.
[0115] In addition, since a predetermined clearance space is formed in the coupling groove of the core member 11a by the above-described inclined surfaces, even when a load is applied to the connection member 11b from the other modular fluid chip 2, the connection member 11b is compressed while being accommodated in the coupling groove, thereby filling the clearance space, so that the modular fluid chip 1 and the other modular fluid chip 2 can be completely in close contact with each other.
[0116] In addition, the connection member 11b can automatically open and close the flow channel 11ba provided inside the connection member 11b according to whether the modular fluid chip 1 and another modular fluid chip 2 are coupled to each other.
[0117] Referring Figure 1 and Figure 3 , when the connection member 11b of the modular fluid chip 1 is coupled to the connection member 11b of another modular fluid chip 2, the flow channel 11ba provided inside can be opened. On the contrary, when the connection member 11b of the modular fluid chip 1 is separated from the connection member 11b of another modular fluid chip 2, the flow channel 11ba can be closed.
[0118] That is, the connection member 11b is formed of an elastic material. Therefore, when the connection member 11b is pressed in the axial direction (X-axis direction) by another modular fluid chip 2 connected to one side thereof, the connection member 11b is compressed in the axial direction and expands in the direction perpendicular to the axial direction (Y-axis direction), thereby opening the flow channel 11ba provided inside the connection member 11b. On the contrary, when the pressure applied from another modular fluid chip 2 is released, the connection member 11b returns by elastic force, thereby closing the flow channel 11ba provided inside the connection member 11b.
[0119] Here, an opening and closing portion 11b1 for opening and closing the flow channel 11ba can be provided inside the connection member 11b.
[0120] The opening and closing portion 11b1 can protrude a predetermined length from the inner surface of the connection member 11b and can contact or be spaced apart from each other according to the deformation of the connection member 11b.
[0121] Meanwhile, although not shown in the drawings, an opening and closing portion (not shown) capable of opening and closing at least one of the flow channels 112 provided in the core member 11a and the flow channel 11ba provided in the connection member 11b may be further included.
[0122] For example, the opening and closing portion may have a known valve structure and is installed in at least one of the core member 11a, the connection member 11b, and the housing 12 to be described later, so as to selectively open and close the above-mentioned flow channels 112 and 11ba. Therefore, the fluid flow can be controlled.
[0123] That is to say, the modular fluid chip 1 can be configured to open and close the flow channel 112 or 11ba by including a separate opening and closing portion, and to open and close the flow channel 11ba by the connection member 11b formed of an elastomer.
[0124] In addition, the modular fluid chip 1 according to the first embodiment of the present disclosure may further include a housing 12.
[0125] Referring to Figure 1 and Figure 2 , the housing 12 is formed as a frame structure having an accommodation space formed therein, and the housing 12 is configured to accommodate the main body 11 therein. In addition, when the housing 12 is connected to another modular fluid chip 2, the housing 12 is configured to communicate the main body 11 accommodated therein with the main body 11 provided in the other modular fluid chip 2.
[0126] In addition, the housing 12 may be composed of a plurality of components that can be divided and assembled.
[0127] For example, the housing 12 may be composed of a lower part and an upper part. The lower part is configured to support the lower surface of the main body 11, and the upper part is configured to be coupled to the lower part and support the outer surface of the main body 11 exposed to the outside of the lower part. Here, a placement groove may be formed in the lower part, and the core member 11a can be placed in the placement groove, and a through hole may be formed in the upper part to expose the upper surface of the core member 11a to the external space.
[0128] In addition, the plurality of components constituting the housing 12 may be coupled to each other using magnetic force.
[0129] For example, magnetic bodies that can be coupled to each other may be provided on the upper surface of the lower part and the corresponding lower surface of the upper part. However, the plurality of components do not have to be combined using magnetic force, and they can be combined with each other by various combination methods.
[0130] In addition, the modular fluid chip 1 according to the first embodiment of the present disclosure may further include a coupling portion.
[0131] Although not specifically shown in the drawings, referring to Figure 1 and Figure 2 , the coupling portion is provided in the housing 12 and may be formed into a structure capable of connecting the modular fluid chip 1 to another modular fluid chip 2 in various directions and at various angles.
[0132] For example, the coupling portion may include at least one protrusion protruding from the outer surface of the housing 12 and at least one receiving groove provided in the outer surface of the housing 12. The protrusion and the receiving groove are formed into corresponding shapes and may be alternately arranged along the outer circumference of the housing 12. In addition, inclined surfaces may be formed on the protrusion and the receiving groove to guide the protrusion and the receiving groove provided in another modular fluid chip 2 to a predetermined position. Therefore, when the modular fluid chip 1 is combined with another modular fluid chip 2, the modular fluid chip 1 and the other modular fluid chip 2 can be automatically aligned with each other.
[0133] In addition, the coupling portion can connect the modular fluid chip 1 to other modular fluid chips 2 by using magnetism.
[0134] For example, the coupling portion may further include a plurality of magnetic members (not shown) installed in the housing 12. The plurality of magnetic members may be formed of a magnetic material having an S pole on one side and an N pole on the other side, and may be installed either inside or outside the housing 12. Therefore, the modular fluid chip 1 and other modular fluid chips 2 can be kept in close contact with each other by the above-mentioned magnetic members provided inside.
[0135] In addition, the coupling portion may further include a blocking member (not shown) provided on one side of the magnetic member to block the magnetic force of the magnetic member.
[0136] For example, the blocking member 124 may be formed of a conductive material or a magnetic material, and may affect the magnetic force exerted by the magnetic member on the flow channel 112, thereby reducing or blocking the magnetic force. Therefore, it is feasible to prevent abnormalities in fluid flow or the function of the modular fluid chip 1 due to magnetism.
[0137] In addition, the coupling portion may further include a fastening portion (not shown) that is respectively installed in the housing 12 of the modular fluid chip 1 and the housing 12 of other modular fluid chips 2, and is coupled to each other by a separate tool, thereby allowing the modular fluid chip 1 and other modular fluid chips 2 to be in close contact with each other.
[0138] For example, the fastening portion may include a rod-shaped shaft portion and a cam portion. The shaft portion is installed in the modular fluid chip 1, the cam portion is installed in other modular fluid chips 2 to accommodate the end portion of the shaft portion therein, and presses the end portion of the shaft portion accommodated therein while rotating in the circumferential direction when an external force is applied by a tool, thereby linearly moving the shaft portion.
[0139] Hereinafter, the modular fluid chip 1 according to the second embodiment of the present disclosure will be described.
[0140] As a reference, for each component used to describe the modular fluid chip 1 according to the second embodiment of the present disclosure, for the sake of convenience of description, the same reference numerals as those used when describing the modular fluid chip 1 according to the first embodiment of the present disclosure will be used. The same or redundant descriptions will be omitted.
[0141] Referring to Figure 1 and Figure 4 , the modular fluid chip 1 according to the second embodiment of the present disclosure includes a main body 11.
[0142] The main body 11 is formed in the form of a module capable of performing a function and is accommodated in a housing 12 configured to surround the main body 11, which will be described later. The main body 11 can be selectively replaced in the housing 12 as needed.
[0143] In addition, at least one flow channel 112 is formed in the main body 11 to guide the flow of fluid.
[0144] At least one flow channel 112 can be configured to perform a preset function on the flowing fluid and guide the flow of fluid in various directions.
[0145] Referring to Figure 4 and Figure 5 , at least one flow channel 112 includes a first flow channel 1121 and a second flow channel 1122 having different heights.
[0146] The first flow channel 1121 can be formed at a position relatively lower than that of the second flow channel 1122. In addition, the first flow channel 1121 and the second flow channel 1122 provided at different heights can guide the flow of fluid in the horizontal direction.
[0147] Moreover, at least one flow channel 112 can further include a third flow channel 1123, a chamber 1124, and a fourth flow channel 1125.
[0148] Referring to Figure 4 and Figure 6 , the third flow channel 1123 can guide the flow of fluid in the vertical direction by connecting the first flow channel 1121 and the second flow channel 1122 provided at different heights to each other.
[0149] The chamber 1124 is formed in any section inside the main body 11 and is connected to at least one of the first flow channel 1121, the second flow channel 1122, the third flow channel 1123, and the fourth flow channel 1124, which will be described later. The chamber 1124 stores and stabilizes the fluid transmitted from one side thereof and then can discharge the fluid to the outside thereof.
[0150] The fourth flow channel 1125 is formed at a position relatively lower than that of the chamber 1124 or the first flow channel 1121 and is connected to at least one of the first flow channel 1121, the second flow channel 1122, the third flow channel 1123, and the chamber 1124. The fourth flow channel 1125 can guide the fluid transmitted through the connected flow channels in the horizontal direction.
[0151] In addition, at least one flow channel 112 can form various fluid movement paths at the rear of the chamber 1124.
[0152] More specifically, at the rear of the chamber 1124, various fluid movement paths can be formed, and the fluid discharged from the chamber 1124 passes through at least any one of the first flow channel 1121, the second flow channel 1122, the third flow channel 1123, and the fourth flow channel 1125 along these fluid movement paths.
[0153] For example, as Figure 4 and Figure 5 shown, at the rear of the chamber 1124, a first fluid movement path can be formed, and the fluid discharged from the chamber 1124 can sequentially pass through the first flow channel 1121, the second flow channel 1122, and the first flow channel 1121 along this first fluid movement path. Optionally, as Figure 7 shown, a second fluid movement path can be formed, and the fluid discharged from the chamber 1124 passes only through the first flow channel 1121 along this second fluid movement path. Further, as Figure 6 shown, at the rear of the chamber 1124, a third fluid movement path can be formed, and the fluid discharged from the chamber 1124 can sequentially pass through the fourth flow channel 1125, the second flow channel 1122, and the first flow channel 1121 along this third fluid movement path. Optionally, as Figure 8 shown, a fourth fluid movement path can be formed, and the fluid discharged from the chamber 1124 can sequentially pass through the fourth flow channel 1125 and the first flow channel 1121 along this fourth fluid movement path. However, the fluid movement paths need not be limited to this, and can be changed into various structures for application.
[0154] Meanwhile, the main body 11 can be provided with air flow holes 11c so as to remove the air staying in the flow channels when the fluid passes through the flow channels.
[0155] Referring to Figures 4 to 8 , the air flow holes 11c allow at least one flow channel 112 to communicate with the external space with each other. Thus, when the fluid passes through the flow channels, the air flow holes 11c discharge the air staying in the flow channels to the external space, thereby enabling the flow in the flow channels.
[0156] In this case, the main body 11 can include an opening and closing member 11d for opening and closing the air flow holes 11c.
[0157] Referring to Figures 4 to 8 , the opening and closing member 11d can be configured to be attached to the main body 11 and open and close the air flow holes 11c.
[0158] Here, the opening and closing member 11d can be configured to remove bubbles from the fluid flowing through at least one flow channel 112.
[0159] Specifically, the opening and closing member 11d can be formed of a hydrophobic material through which hydrophilic fluid cannot pass and only gas can pass, or can be formed in the form of a fibrous structure with a hydrophobic material coated on its surface. Here, the fibrous structure can be formed of non-woven fabric, glass fiber, or sponge.
[0160] For example, the opening and closing member 11d formed of a hydrophobic material can be formed of one or more hydrophobic materials selected from the group consisting of Polytetrafluro ethylene (PTFE), Polyethylene Terephtalate (PET), and Polyvinyl Chloride.
[0161] In addition, the opening and closing member 11d can be formed of a hydrophilic material through which hydrophobic fluid cannot pass and only gas can pass, or can be formed in the form of a fibrous structure with a hydrophilic material coated on its surface.
[0162] Moreover, the opening and closing member 11d can include both hydrophobic and hydrophilic materials in order to remove bubbles from a mixed fluid in which hydrophilic fluid and hydrophobic fluid are mixed.
[0163] For example, the opening and closing member 11d can be formed in a stacked form with a hydrophobic material provided on one surface and a hydrophilic material provided on the other surface. However, the opening and closing member 11d is not limited thereto and can be changed into various forms so as to be applied under conditions capable of performing the same function.
[0164] Refer to Figure 1 and Figure 4 , the main body 11 can include a core member 11a and at least one connecting member 11b provided on the core member 11a.
[0165] The above at least one flow channel 112 can be formed inside the core member 11a, and the core member 11a can be connected to the other modular fluid chip 2 through the above connecting member 11b.
[0166] In addition, the core member 11a can be integrally formed through 3D printing processing, or can be formed in the form of a plurality of modules that can be combined and separated from each other through injection molding processing. However, the core member 11a does not have to be limited thereto, and various techniques such as MEMS, CNC machining, imprinting, polymer casting, etc. can be used for manufacturing.
[0167] In addition, the core member 11a can be formed to be wholly or partially transparent so that the flow of fluid flowing into the inside from the outside of the core member 11a can be visually confirmed.
[0168] The connecting member 11b is disposed in the core member 11a and connected to the connecting member 11b disposed in the other modular fluid chip 2 such that at least one flow channel 112 can communicate with the flow channel 112 disposed in the other modular fluid chip 2.
[0169] The connecting member 11b can be formed into a tubular shape having a flow channel 11ba therein, and can be integrally provided with the core member 11a, or can be separable from the outer surface of the core member 11a.
[0170] In addition, the connecting member 11b can be configured to form an interface at the contact portion when contacting the core member 11a and another connecting member 11b.
[0171] More specifically, the connecting member 11b can be formed of an elastic material capable of elastic deformation, and can form an interface at the contact portion when contacting the core member 11a and another connecting member 11b. Here, an adhesive layer can be provided on one surface and the other surface of the connecting member 11b.
[0172] In addition, the modular fluid chip 1 according to the second embodiment of the present disclosure can further include a housing 12.
[0173] Referring to Figure 1 and Figure 4 , the housing 12 is formed into a frame structure having an accommodation space formed therein, and the housing 12 is configured to accommodate the main body 11. In addition, when the housing 12 is connected to the other modular fluid chip 2, the housing 12 is configured to allow the accommodated main body 11 to communicate with the main body 11 disposed in the other modular fluid chip 2.
[0174] In addition, the modular fluid chip 1 according to the second embodiment of the present disclosure can further include a coupling portion.
[0175] Although not specifically shown in the drawings, referring to Figure 1 and Figure 2 , the coupling portion is disposed in the housing 12 and can be formed into a structure capable of connecting the modular fluid chip 1 to the other modular fluid chip 2 in various directions and at various angles.
[0176] Hereinafter, the modular fluid chip 1 according to the third embodiment of the present disclosure will be described.
[0177] As a reference, for each component for describing the modular fluid chip 1 according to the third embodiment of the present disclosure, for the sake of convenience of description, the same reference numerals as those used when describing the modular fluid chip 1 according to the first and second embodiments of the present disclosure will be used. The same or redundant descriptions will be omitted.
[0178] Refer to Figure 9 , according to the modular fluid chip 1 of the third embodiment of the present disclosure, it includes a main body 11, and the main body 11 has at least one flow channel 112 formed inside the main body 11.
[0179] The main body 11 includes a core member 11a and a thin film member 11e.
[0180] The core member 11a can be integrally formed by 3D printing processing, or can be formed into a form of multiple modules that can be combined and separated from each other by injection molding processing.
[0181] In addition, the core member 11a can be formed to be wholly or partially transparent, so that the flow of the fluid flowing into the inside from the outside of the core member 11a can be visually confirmed. For example, the core member 11a can be formed of at least one of amorphous materials such as glass, wood, polymer resins, metals, and elastomers or can be formed by a combination thereof.
[0182] In addition, the core member 11a has at least one flow channel 112 formed in the core member 11a.
[0183] More specifically, the core member 11a includes a plurality of first diversion channels 1126 that guide the fluid flow in the vertical direction and at least one chamber 1128 that stores the fluid.
[0184] Furthermore, refer to Figure 1 and Figure 3 , the core member 11a can be connected to other modular fluid chips 2 through a connecting member 11b provided on its outer surface.
[0185] The connecting member 11b is connected to the connecting member 11b provided in other modular fluid chips 2, so that at least one flow channel 112 provided in the modular fluid chip 1 can communicate with the flow channel 112 provided in other modular fluid chips 2.
[0186] In addition, the connecting member 11b can be configured to form an interface at the contact portion when contacting the core member 11a and another connecting member 11b.
[0187] More specifically, the connecting member 11b can be formed of an elastic material that can elastically deform, and when contacting the core member 11a and another connecting member 11b, an interface can be formed at the contact portion. Here, an adhesive layer can be provided on one side and the other side of the connecting member 11b.
[0188] Alternatively, the connecting member 11b may be provided integrally with the core member 11a, or may be coupled to the core member 11a and separable from the core member 11a.
[0189] Referring Figure 9 , the thin film member 11e may be attached to the outer surface of the core member 11a to form a flow channel.
[0190] More specifically, the thin film member 11e is attached to the outer surface of the core member 11a to allow a plurality of first diversion channels 1126 to communicate with each other.
[0191] Referring Figure 9 and Figure 10 , the thin film member 11e may include a first thin film layer 11e1 and a second thin film layer 11e2.
[0192] The first thin film layer 11e1 may be attached to the outer surface (upper and lower surfaces) of the core member 11a. Additionally, at least one second diversion channel 1127 may be formed inside the first thin film layer 11e1, and at least one second diversion channel 112 is connected to the plurality of first diversion channels 1126 provided in the core member 11a to guide fluid flow in the horizontal direction.
[0193] The second thin film layer 11e2 is attached to the outer surface of the first thin film layer 11e1 to block the second diversion channel 1127 from being exposed to the external space. Here, air flow holes 11c may be provided in the second thin film layer 11e2 so as to remove air staying in the flow channel when fluid passes through the flow channel.
[0194] For example, the first thin film layer 11e1 may be applied as a tape having adhesive layers provided on its upper and lower surfaces, and the second thin film layer 11e2 may be applied as a transparent film, so that the flow channel 112 of the core member 11a can be confirmed. However, the first thin film layer 11e1 and the second thin film layer 11e2 are not necessarily limited thereto, and may be changed into various materials for application.
[0195] The air flow holes 11c allow at least one flow channel 112 and the external space to communicate with each other. Thus, when fluid passes through the flow channel, the air staying in the flow channel can be discharged to the external space, thereby enabling flow in the flow channel.
[0196] In this case, the main body 11 may include an opening and closing member 11d for opening and closing the air flow holes 11c.
[0197] The opening and closing member 11d may be configured to be attached to the main body 11 and open and close the air flow holes 11c.
[0198] More specifically, the opening and closing member 11d can be formed of a hydrophobic material through which liquid cannot pass and only gas can pass, so that only bubbles can be removed from the fluid flowing through at least one flow channel 112.
[0199] In addition, the modular fluid chip 1 according to the third embodiment of the present disclosure may further include a housing 12.
[0200] Referring Figure 1 and Figure 9 , the housing 12 is formed in a frame structure having an accommodation space formed therein, and the housing 12 is configured to accommodate the main body 11. In addition, when the housing 12 is connected to another modular fluid chip 2, the housing 12 is configured to allow the accommodated main body 11 to communicate with the main body 11 provided in the other modular fluid chip 2.
[0201] In addition, the modular fluid chip 1 according to the second embodiment of the present disclosure may further include a coupling portion.
[0202] Although not specifically shown in the drawings, the coupling portion is provided in the housing 12 and may be formed in a structure capable of connecting the modular fluid chip 1 to another modular fluid chip 2 in various directions and at various angles.
[0203] Hereinafter, the modular fluid chip 1 according to the fourth embodiment of the present disclosure will be described.
[0204] As a reference, for each component for describing the modular fluid chip 1 according to the fourth embodiment of the present disclosure, for the sake of convenience of description, the same reference numerals as those used when describing the modular fluid chip 1 according to the first embodiment of the present disclosure will be used. The same or redundant descriptions will be omitted.
[0205] Referring Figure 12 and Figure 13 , the modular fluid chip 1 according to the fourth embodiment of the present disclosure includes a main body 11.
[0206] The main body 11 is formed in the form of a module capable of performing one function, and is accommodated in the housing 12, and if necessary, the main body 11 can be selectively replaced in the housing 12. In addition, the main body 11 can be formed in a shape corresponding to the inner surface of the housing 12 having an accommodation space, and based on the Z-axis direction in the drawings, the main body 11 can be formed to have the same height as the housing 12. Technologies such as MEMS, 3D printing, injection molding, CNC machining, imprinting, polymer casting, etc. can be used to manufacture the main body 11.
[0207] In addition, when the main body 11 is connected to the housing 12, the main body 11 can be accurately fixed to a set position and can be formed into a polyhedral structure such that the main body 11 is in surface contact with the inner surface of the housing 12.
[0208] In addition, the main body 11 can be formed to be wholly or partially transparent such that the flow of fluid flowing into the interior from the exterior of the main body 11 can be visually confirmed. For example, the main body 11 can be formed of at least one of amorphous materials such as glass, wood, polymer resins, metals, and elastomers or can be formed by a combination thereof.
[0209] In addition, a part of the main body 11 can be formed of an elastomeric material.
[0210] For example, the part of the main body 11 where fluid flows or comes into contact with other components can be formed of an elastomeric material. When the main body 11 is partially formed of an elastomeric material, the main body 11 can be manufactured by double injection molding or the like.
[0211] Referring to Figure 13 and Figure 17 , a first hole 111 is formed in the main body 11 to guide the flow of fluid.
[0212] The first hole 111 communicates with a second hole 121 of the housing 12 and a fluid passage 112 formed inside the main body 11, which will be described later, so as to guide the fluid flow in at least one of the X-axis direction and the Y-axis direction. For example, the first hole 111 is formed in a predetermined section from the outer surface of the main body 11 toward the interior of the main body 11, but can be formed in a section smaller in size than the section where the fluid passage 112 is formed.
[0213] In addition, the first hole 111 can be formed into a shape corresponding to the second hole 121 provided in the housing 12 and the fluid passage 112 provided in the main body 11. Therefore, the first hole 111 can prevent the phenomenon of unstable fluid flow or increased fluid pressure between the housing 12 and the main body 11 during fluid flow. For example, the first hole 111 can have a circular cross-section as shown in Figure 18 (a), or can have a polygonal or elliptical cross-section although not shown in the drawings. However, the shape of the first hole 111 is not limited thereto, and can be formed in various ways within a limit where the width w is equal to or greater than 10 nm and equal to or less than 1 Cm.
[0214] Here, the fact that the first hole 111 and the second hole 121 have corresponding shapes and sizes to each other and form a linear fluid path relative to each other may allow for a predictable flow rate when the fluid moves from one module to another. In some conventional microfluidic flow devices, the fluid is transported through tubes. In the case of a device using tubes, a difference in channel width occurs at the part where the tube and the device are connected to each other, or a space is created in the channel, resulting in vortices in the fluid. Such vortices not only cause rapid changes in the flow rate but may also deform the droplet shape. Additionally, it may cause physical impacts on the substances in the fluid or disrupt the movement of the substances. Therefore, the fact that the first hole 111 of the main body 11 and the second hole 121 of the housing 12 have the same width and are arranged in a straight line allows for a stable flow rate of the fluid and a stable movement of the substances, in addition to simply ensuring the function of connecting between the modules. Moreover, regardless of the function or shape of the module in the module system of the present application, the housing 12 and the second hole 121 of the housing 12 can ensure the above-mentioned fluid stability.
[0215] In addition, a fluid channel 112 may be formed in the main body 11.
[0216] Referring to Figure 13 and Figure 17 , the fluid channel 112 may communicate with at least one first hole 111, allowing the fluid to flow. For example, referring to Figure 18 (c), the fluid channel 112 may have a polygonal cross-section, or may have a circular or elliptical cross-section although not shown in the drawings. However, the shape of the fluid channel 112 is not limited thereto, and it may be formed in various ways within the limit where the width w is equal to or greater than 10 nm and equal to or less than 1 Cm.
[0217] In addition, the fluid channel 112 may be configured to perform a preset function on the flowing fluid and guide the fluid flow in various directions.
[0218] For example, referring to Figures 14 to 16 , inside the main body 11, at least one of the following fluid channels may be formed: a straight fluid channel 112 ( Figure 14 (a), (b)), a streamlined fluid channel 112 ( Figure 14 (c), (d), (e)), a fluid channel 112 having at least one well ( Figure 14 (f), (g), (h)), a fluid channel 112 having a valve ( Figure 15 (a), (b), (c), (d), (e)), a fluid channel 112 having at least one branch ( Figure 15 (f), (g)), a cross-shaped fluid channel 112 ( Figure 15 (h),Figure 16 in (a)) of, the Y-shaped fluid channel 112 ( Figure 16 in (b)) of, a fluid channel with a sensor (not shown), a fluid channel with an electrical output unit (not shown), and a fluid channel with an optical output unit (not shown). However, the fluid channel 112 is not limited thereto and can be changed into various structures and shapes for applications. In addition, the fluid channel 112 can be manufactured by combining the above channels.
[0219] Meanwhile, another modular fluid chip 2 connected to the modular fluid chip 1 may include a main body 11 capable of performing functions different from those of the main body 11 of the modular fluid chip 1.
[0220] That is, different types of fluid channels 112 can be formed in the main body 11 of the modular fluid chip 1 and the main body 11 of another modular fluid chip 2.
[0221] Therefore, a plurality of modular fluid chips 1 and 2 connected to each other to implement the fluid flow system 1000 can perform different functions on the fluid flowing therein. Here, each of the plurality of modular fluid chips 1 and 2 connected to each other can be formed to perform only one function. For example, when one fluid chip 1 has a Y-shaped fluid channel 112 and performs a mixing function, another fluid chip 2 connected to the fluid chip 1 may include a fluid channel 112 of a type different from the above Y-shaped fluid channel 112 and perform a function different from that of the fluid chip 1.
[0222] In addition, the modular fluid chip 1 according to the fourth embodiment of the present disclosure includes a housing 12.
[0223] Referring to Figure 13 and Figure 17 , the housing 12 is formed into a frame structure having an accommodation space formed therein, and the housing 12 is configured to accommodate the main body 11. In addition, a second hole 121 is formed in the housing 12, and when the main body 11 is accommodated in the accommodation space, the second hole 121 corresponds to at least one first hole 111 provided in the main body 11 and allows fluid to flow.
[0224] The second hole 121 is formed at at least one position along the outer periphery of the housing 12 and communicates with the first hole 111 of the main body 11, thereby guiding fluid flow in at least one of the X-axis direction and the Y-axis direction.
[0225] In addition, the second hole 121 is formed to correspond to the shape of the first hole 111 provided in the main body 11, and can prevent unstable fluid flow or an increase in fluid pressure between the housing 12 and the main body 11 during fluid flow. For example, the second hole 121 can be as Figure 18(b) has a circular cross-section, or may have a polygonal or elliptical cross-section even though not shown in the drawings. However, the shape of the second hole 121 is not limited thereto, and may be formed in various ways within the limit where the width w is equal to or greater than 10 nm and equal to or less than 1 Cm.
[0226] In addition, the housing 12 may be formed of at least one of ceramics, metals, and polymers. Here, ceramics mean materials composed of oxides, carbides, and nitrides made by combining metal elements such as silicon, aluminum, titanium, zirconium, etc. with oxygen, carbon, and nitrogen. The housing 12 may be formed of one of the above ceramic materials, or may be formed of a ceramic mixture mixed with at least one or more of the above ceramic materials. And, metals mean materials composed of elements called metals in the periodic table of chemistry, such as Au, Mg, Ti, Cr, Mn, Fe, Co, Ni, Cu, Zn, Ga, Al, Zr, Nb, Mo, Ru, Ag, Sn, etc. The housing 12 may be formed of any one of the above metal materials, or may be formed of a metal mixture mixed with at least one or more of the above metal materials. And, polymers mean materials composed of COC, PMMA, PDMS, PC, TIPP, CPP, TPO, PET, PP, PS, PEEK, polytetrafluoroethylene (Teflon), PI, PU, etc. The housing 12 may be formed of any one of the above polymer materials, or may be formed of a polymer mixture mixed with at least one or more of the above polymer materials. In addition, the housing 12 may be formed of a mixture of the above ceramics, metals, and polymers. However, the housing 12 does not have to be limited thereto, and may be formed of various materials.
[0227] In addition, the housing 12 may be formed of a material similar to the above-mentioned main body 11, or may be formed of a material different from the main body 11.
[0228] More specifically, the housing 12 formed of at least one of ceramics, metals, and polymers and the main body 11 formed of at least one of polymer resins, amorphous materials, metals, and elastomers may be formed of materials similar to each other, or may be formed of materials different from each other.
[0229] Thus, the housing 12 and the main body 11 can maximize the adhesion force of their surface contact portions to prevent mutual separation and prevent fluid leakage in their connection portions.
[0230] Here, the housing 12 formed separately from the main body 11 is to ensure the stable flow of fluid when the modular fluid chip 1 is connected as described above, but also to facilitate the modularization of the modular fluid chip 1. That is, since the position of the second hole 121 of the housing 12 is standardized, when designing and manufacturing the main body 11, as long as the main body 11 is manufactured to have a standardized inlet or outlet or the first hole 111, the fluid connection or interface connection between the modules can be ensured. In addition, when only the main body 11 is newly manufactured and connected to the housing 12, a module with a new function can be assembled.
[0231] In addition, the housing 12 includes a fluid connection member 17.
[0232] The fluid connection member 17 is configured to connect the modular fluid chip 1 to other modular fluid chips 2.
[0233] Referring to Figure 33 and Figure 34 , the fluid connection member 17 can be formed in the form of a sheet or pad and can be detachably mounted on the outer surface of the housing 12. Here, a placement groove 123 corresponding to the fluid connection member 17 can be formed in the outer surface of the housing 12 so that the fluid connection member 17 can be placed in the placement groove 123. In addition, a third hole 171 aligned with the first hole 111 and the second hole 121 can be formed in the fluid connection member 17.
[0234] In addition, referring to Figure 35 and Figure 36 , the fluid connection member 17 can be configured to form an interface when contacting another fluid connection member 17.
[0235] More specifically, the fluid connection member 17 can be formed of an elastomer material that can be elastically deformed, and when contacting another fluid connection member 17, an interface is formed at the contact portion. Here, an adhesive layer can be provided on one surface of the fluid connection member 17, and when the fluid connection member 17 contacts another fluid connection member 17, the adhesive layer can adhere to one surface of the other fluid connection member 17.
[0236] However, the fluid connection member 17 is not limited thereto and can be changed into various shapes or various materials and thus applied under the condition of being able to perform the same function. For example, when manufacturing the housing 12, the fluid connection member 17 can be integrally provided on the outer surface of the housing 12 by double injection molding and can be formed into a circular or polygonal ring shape having a hole formed in the center, or can be formed into a plate-shaped plug shape. In addition, the fluid connection member 17 can be formed of at least one of a polymer resin, an amorphous material, and a metal, and can include at least one of chlorinated polyethylene, dimethyl ethylene, silicone rubber, acrylic resin, amide resin, epoxy resin, phenolic resin, polyester-based resin, polyvinyl resin, ethylene propylene rubber, polyvinyl butyral resin, polyurethane resin, and nitrile-based rubber.
[0237] Therefore, when the modular fluid chip 1 is connected to another modular fluid chip 2 in the horizontal or vertical direction, the fluid connection member 17 provided in the modular fluid chip 1 is in close contact with the fluid connection member 17 provided in the other modular fluid chip 2 and forms an interface. Thus, the connection portion between the modular fluid chip 1 and the other modular fluid chip 2 can be completely airtight, thereby preventing fluid leakage. Here, a coupling unit 122 having magnetism to maximize the adhesion force of the fluid connection member 17 can be provided on the inner surface of each housing 12 provided in the modular fluid chip 1 and the other modular fluid chip 2.
[0238] In addition, the fluid connection member 17 can be provided on at least one of the outside and the inside of the housing 12.
[0239] Referring to Figure 37 , the fluid connection member 17 provided outside the housing 12 can be in close contact with another fluid connection member 17 and form an interface, and the fluid connection member 17 provided inside the housing 12 can be in close contact with the main body 11 and form an interface. Here, a magnetic coupling unit 122 can be provided around the fluid connection member 17 provided inside the housing 12. Therefore, it is feasible to improve the airtight performance between the modular fluid chip 1 and the other modular fluid chips 2 by maximizing the adhesion force of the fluid connection member 17 provided outside the housing 12.
[0240] Furthermore, the fluid connection member 17 can be formed into a structure capable of being coupled to the housing 12.
[0241] Referring to Figure 38 and Figure 39, a protruding portion 173 having a protruding shape may be formed on the fluid connection member 17, and the protruding portion 173 protrudes from the outer surface of the fluid connection member 17 by a predetermined length and is inserted into a seating groove 123 formed in the housing 12. Accordingly, the fluid connection member 17 is more stably coupled to the housing 12 to restrict the movement of the housing 12. In addition, even when the modular fluid chip 1 is coupled to another modular fluid chip 2, it is feasible to prevent the fluid connection member 17 from being separated from the housing 12.
[0242] Meanwhile, although not shown in the drawings, a recessed portion having a groove shape may be formed in the fluid connection member 17, and the recessed portion may be recessed from the outer surface of the fluid connection member 17 by a predetermined depth and may be coupled to a protrusion formed in the housing 12.
[0243] However, the coupling structure provided in the fluid connection member 17 need not be limited thereto and may be changed into various shapes for application.
[0244] In addition, the fluid connection member 17 may be formed into a structure capable of directly communicating with the main body 11 to be connected to another modular fluid chip 2.
[0245] Referring to Figure 40 , the fluid connection member 17 is accommodated in the housing 12 but may pass through the housing 12 to be in close contact with the outer surface of the main body 11. Accordingly, a third hole 171 provided in the fluid connection member 17 directly communicates with a first hole 111 provided in the main body 11 and allows fluid to flow.
[0246] That is, the fluid connection member 17 installed through the housing 12 is in close contact with the fluid connection member 17 of another modular fluid chip 2 on one side thereof to form an interface, and is in close contact with the outer surface of the main body 11 on the other side thereof to form an interface, thereby minimizing points where fluid may leak. Accordingly, stable fluid flow may be allowed.
[0247] For example, the fluid connection member 17 may include a seating portion 172 and a protruding portion 173. The seating portion 172 is seated in a seating groove 123 formed in the outer surface of the housing 12 and is connected to another modular fluid chip 2. The protruding portion 173 protrudes from one surface of the seating portion 172 by a predetermined length to pass through the housing 12 and is in close contact with the outer surface of the main body 11 to form an interface. Here, a recessed portion 1231 may be provided in the inner surface of the housing 12, and the recessed portion 1231 is formed to correspond to the shape of the outer surface of the protruding portion 173 and supports the protruding portion 173. Further, a magnetic coupling unit 122, which will be described later, may be further provided around the protruding portion 173 to maximize the adhesion force of the seating portion 172.
[0248] In addition, while being directly connected to the main body 11, the fluid connection member 17 may be formed into a structure that is divided into multiple parts.
[0249] Referring to Figure 41 and Figure 42 , the fluid connection member 17 may include a mounting portion 172, a protruding portion 173, and an O-ring 174.
[0250] The mounting portion 172 may be mounted in a mounting groove 123 formed in the outer surface of the housing 12, and may be in close contact with other modular fluid chips 2 to form an interface.
[0251] The protruding portion 173 may be separated from the mounting portion 172, and is received in a recessed portion 1231 provided inside the housing 12, and may be in close contact with the outer surface of the main body 11 and form an interface.
[0252] The O-ring 174 is provided between the mounting portion 172 and the protruding portion 173 to connect the mounting portion 172 and the protruding portion 173 to each other, and when connecting the modular fluid chip 1 and other modular fluid chips 2, evenly distributes the load acting on the fluid connector 17 in the axial direction, thereby preventing the mounting portion 172 or the protruding portion 173 from deforming. For example, the O-ring 174 is formed of an elastomer, plastic, or metal material, and another hole communicating with a third hole 171 formed in the mounting portion 172 and the protruding portion 173 may be formed inside the O-ring 174.
[0253] However, the fluid connector 17 is not necessarily limited thereto, and may be changed into various forms for application.
[0254] In addition, the modular fluid chip 1 according to the fourth embodiment of the present disclosure may further include a coupling unit 122.
[0255] Referring to Figure 11 and Figure 13 , the coupling unit 122 may be configured to couple the modular fluid chip 1 to other modular fluid chips 2 in the horizontal direction (X-axis direction and Y-axis direction).
[0256] More specifically, the coupling unit 122 is received in the housing 12 or provided integrally with the housing 12 to connect the modular fluid chip 1 to other modular fluid chips 2 in the horizontal direction (X-axis direction and Y-axis direction), and at the same time, may automatically align and fix the modular fluid chip 1 with other modular fluid chips 2.
[0257] Accordingly, a plurality of modular fluid chips 1 and 2 connected to each other in the horizontal direction can implement a fluid flow system 1000 including a plurality of fluid flow sections and fluid analysis sections.
[0258] Here, the coupling unit 122 may include a magnetic material.
[0259] Referring to Figure 11 and Figure 13 , the coupling unit 122 is formed of a magnetic body having an S pole on one side and an N pole on the other side, and can be installed inside the housing 12. Thus, the modular fluid chip 1 connected to another modular fluid chip 2 can maintain a state of surface contact between the modular fluid chip 1 and the other modular fluid chip 2.
[0260] Furthermore, referring to Figure 19 and Figure 20 , the coupling unit 122 can be installed outside the housing 12. In this case, a mounting groove 123 for accommodating the coupling unit 122 can be formed in the outer surface of the housing 12. Therefore, the coupling unit 122 installed outside the housing 12 can further maximize the bonding force between the modular fluid chip 1 and the other modular fluid chip 2.
[0261] However, the coupling unit 122 is not limited thereto, and can be changed into various structures. For example, the coupling unit 122 can be provided on both the inside and outside of the housing 12, and can be formed in a form capable of changing the polarity direction as needed. In addition, the coupling unit 122 can include not only a magnetic body such as a permanent magnet, but also at least one of various magnetic materials capable of implementing the same function as the magnetic body.
[0262] In addition, referring to Figure 13 and Figure 19 , when the coupling unit 122 mounted on the housing 12 is connected to another modular fluid chip 2, the coupling unit 122 can be set at a position having the same central axis as the second hole 121 of the modular fluid chip 1, so that the second hole 121 of the other modular fluid chip 2 and the second hole 121 of the modular fluid chip 1 can be aligned and communicated with each other. Here, the housing 12 can be provided with a mounting groove 123, and the coupling unit 122 can be mounted in the mounting groove 123. In addition, the coupling unit 122 accommodated in the mounting groove 123 can be exposed to the outside of the housing 12, and can be formed to correspond to the shape of the mounting groove 123 so as not to interfere with other components.
[0263] In addition, the coupling unit 122 provided in the modular fluid chip 1 can be formed in a structure capable of directly connecting to the coupling unit 122 provided in another modular fluid chip 2.
[0264] Referring toFigure 26 The coupling unit 122 provided in the modular fluid chip 1 and the corresponding coupling unit 122 of the other modular fluid chip 2 may include corresponding protruding portions 1223 or recessed portions 1224. For example, the protruding portion 1223 and the recessed portion 1224 may be formed in corresponding convex and concave shapes. In addition, the protruding portion 1223 and the recessed portion 1224 may be formed in a cylindrical or polygonal column shape to prevent each modular fluid chip from separating or moving when they are coupled to each other.
[0265] Refer to Figures 27 to 30 The coupling unit 122 provided in the modular fluid chip 1 may include a fastening portion 1225, and the fastening portion 1225 may be connected to the other modular fluid chip 2.
[0266] Refer to Figure 27 The coupling unit 122 provided in the modular fluid chip 1 may include a fastening portion 1225, and one end of the fastening portion 1225 has a hook shape so as to be coupled to the other modular fluid chip 2. In this case, a fastening groove 1226 corresponding to the fastening portion 1225 provided in the modular fluid chip 1 may be formed in the other modular fluid chip 2.
[0267] Refer to Figure 28 The coupling unit 122 provided in the modular fluid chip 1 may include a fastening portion 1225, and the fastening portion 1225 has a bolt shape with threads on its outer peripheral surface so as to be coupled to the other modular fluid chip 2. In this case, a fastening groove 1226 corresponding to the fastening portion 1225 provided in the modular fluid chip 1 may be formed in the other modular fluid chip 2.
[0268] Refer to Figure 29 The coupling unit 122 provided in the modular fluid chip 1 may include a fastening portion 1225, and the fastening portion 1225 has a "∩" shape in the form of a pin so as to be coupled to the other modular fluid chip 2. In this case, a fastening groove 1226 into which the fastening portion 1225 in the form of a pin can be inserted may be formed in the modular fluid chip 2 different from the modular fluid chip 1.
[0269] Refer to Figure 30 The coupling unit 122 provided in the modular fluid chip 1 may be coupled to the other modular fluid chip 2 through the bolt-shaped fastening portion 1225. In this case, a fastening groove 1226 for fastening the bolt-shaped fastening portion 1225 may be formed in the modular fluid chip 2 different from the modular fluid chip 1.
[0270] In addition, the modular fluid chip 1 according to the fourth embodiment of the present disclosure may further include a cover 13.
[0271] Refer to Figure 12 and Figure 13 The cover 13 can be configured to be connected to at least one of the upper and lower parts of the housing 12 in the vertical direction (Z-axis direction) and protect the main body 11.
[0272] The cover 13 can be formed to correspond to the shape of the housing 12 and can be formed of a transparent material so that when the cover 13 is connected to the housing 12, the main body 11 can be seen from the outside. Further, an optical cable or an electric cable (not shown) can be installed inside the cover 13 as needed.
[0273] In addition, the cover 13 and the housing 12 can further include fastening means 131 for connecting to each other.
[0274] More specifically, the cover 13 and the housing 12 can each be provided with a coupling part protruding outward from one surface thereof and an insertion groove into which the coupling part provided at a relative position can be inserted. For example, the coupling part formed on the cover 13 and the coupling part formed on the housing 12 can be formed in the same shape or different shapes. However, the fastening means 131 provided on the cover 13 and the housing 12 is not limited thereto, and various structures in which they are fastened to each other can be applied.
[0275] Meanwhile, the modular fluid chip 1 can be connected to other modular fluid chips 2 in the vertical direction to implement a fluid flow system 1000.
[0276] Refer to Figure 21a in (a), the modular fluid chip 1 can be connected to other modular fluid chips 2 in the vertical direction (Z-axis direction) to implement a fluid flow system 1000 including a plurality of fluid flow sections and fluid analysis sections. And, refer to Figure 21a in (b), the modular fluid chip 1 can be connected to other modular fluid chips 2 in the horizontal direction (X-axis direction) and the vertical direction (Z-axis direction) to implement another type of fluid flow system 1000. Here, the second hole 121 provided in the housing 12 of the modular fluid chip 1 can communicate with the second hole 121 provided in the housing 12 of other modular fluid chips 2. Further, in Figure 21a in (b), the modular fluid chip 1 is shown as being connected to other modular fluid chips 2 only in the X-axis direction. However, the modular fluid chip 1 can be connected to other modular fluid chips 2 not only in the X-axis direction but also in the Y-axis direction or the X-axis direction.
[0277] That is to say, the modular fluid chip 1 is configured to be connected to other modular fluid chips 2 in the horizontal and vertical directions, thereby generating fluid flow paths in all directions. For example, the number of modular fluid chips 2 connected to each other in at least one of the horizontal and vertical directions to form a fluid flow system 1000 may be from 1 to 10,000.
[0278] Meanwhile, referring to Figure 21a , the modular fluid chip 1 connected to other modular fluid chips 2 in the vertical direction (Z-axis direction) can be coupled to other modular fluid chips 2 in a state where the cover 13 is not coupled.
[0279] At this time, the second hole 121 provided in the housing 12 may be formed into a structure capable of guiding the flow of fluid into the second hole 121 provided in other modular fluid chips 2 provided on the upper and lower sides of the modular fluid chip 1.
[0280] Referring to Figure 22a and Figure 23a , the modular fluid chip 1 connected to other modular fluid chips 2 in the vertical direction (Z-axis direction) is composed of a main body 11 and a housing 12, and at least one second hole 121 formed in the housing 12 may include a horizontal portion 1211 and a vertical portion 1212. The horizontal portion 1211 communicates with the first hole 111 formed in the main body 11 and is arranged parallel to the fluid passage 112, and the vertical portion 1212 communicates with the horizontal portion 1211 and is vertically bent in the housing 12 to communicate with the external space of the housing 12. Here, the housing 12 may include a plurality of coupling units 122, and the plurality of coupling units 122 can connect other modular fluid chips 2 provided on the upper and lower sides of the housing 12 to the modular fluid chip 1. Each of the plurality of coupling units 122 may be formed of a magnetic body having an S pole on one side and an N pole on the other side, and may be installed in the placement grooves 123 provided on the upper and lower surfaces of the housing 12. Further, the plurality of coupling units 122 may be provided with through holes, and the through holes communicate with each vertical portion 1212 provided in the housing 12. The through hole is formed to correspond to the shape of the vertical portion 1212 and may have the same central axis as the vertical portion 1212.
[0281] Therefore, as Figure 25a and Figure 25b shown, when the housing 12 of the modular fluid chip 1 is connected to other modular fluid chips 2 in the horizontal or vertical direction, the first hole 111 and the second hole 121 provided in the modular fluid chip 1 can be aligned and communicated with the first hole 111 and the second hole 121 provided in other modular fluid chips 2.
[0282] In addition, the above-described modular fluid chip 1 can be formed into a structure that can be connected to other modular fluid chips 2 when the lid 13 is connected to the housing 12.
[0283] Referring to Figure 22b and Figure 23b , the lid 13 may be provided with an extension hole 132 that communicates with the vertical portion 1212 of the second hole 121 formed in the housing 12 and communicates with other modular fluid chips 2.
[0284] In addition, the housing 12 and the lid 13 may include a plurality of coupling units 122 that can connect other modular fluid chips 2 disposed on the upper and lower sides of the modular fluid chip 1 to the modular fluid chip 1.
[0285] The plurality of coupling units 122 may be formed of a magnetic body having an S pole on one side and an N pole on the other side, and may be installed in the housing 12 and the lid 13.
[0286] More specifically, the plurality of coupling units 122 may include a first magnetic portion 1221 and a second magnetic portion 1222. The first magnetic portion 1221 is installed on the upper and lower surfaces of the housing 12, and the second magnetic portion 1222 is installed on the inner surfaces of the corresponding lids 13 connected to the upper and lower sides of the housing 12. Here, one side of the second magnetic portion 1222 installed in the lid 13 can be connected to the first magnetic portion 1221 installed in the housing 12 by magnetic force, and the other side of the second magnetic portion 1222 can be connected to the second magnetic portion 1222 installed in the lid 13 of the other modular fluid chip 2 by magnetic force. Further, the housing 12 and the lid 13 may be provided with placement grooves 123 for accommodating the first magnetic portion 1221 and the second magnetic portion 1222.
[0287] In addition, through holes communicating with the vertical portion 1212 formed in the housing 12 may be formed in the first magnetic portion 1221. The through holes formed in the first magnetic portion 1221 are formed to correspond to the shape of the vertical portion 1212 and may have the same central axis as the vertical portion 1212. In addition, through holes communicating with the extension hole 132 formed in the lid 13 may be formed in the second magnetic portion 1222. The through holes formed in the second magnetic portion 1222 are formed to correspond to the shape of the extension hole 132 and may have the same central axis as the extension hole 132.
[0288] In addition, the lid 13 connected to the upper side of the housing 12 and the lid 13 connected to the lower side of the housing 12 may further include a coupling structure that can be coupled to other modular fluid chips 2 connected to the upper and lower sides of the modular fluid chip 1.
[0289] More specifically, the cover 13 provided on the upper side of the housing 12 may be provided with a protrusion 133 capable of being coupled to a groove 134 provided in another modular fluid chip 2, and the cover 13 provided on the lower side of the housing 120 may be provided with a groove 134 capable of being coupled to the protrusion 133 provided in another modular fluid chip 2. For example, the protrusion 133 and the groove 134 may be formed in shapes corresponding to each other.
[0290] Referring to Figure 24a , a coupling unit 122 in the form of a magnetic body may be installed outside the cover 13 so as to further maximize the bonding force between the modular fluid chip 1 and another modular fluid chip 2.
[0291] Here, the coupling unit 122 in the form of a magnetic body may be formed in the shape of a tablet as shown in (a) of Figure 24a , or may be formed in the shape of a panel as shown in (b) of Figure 24a , and may be installed on the outer surface of the cover 13. In this case, a seating groove 123 for seating the coupling unit 122 may be formed in the outer surface of the cover 13.
[0292] Meanwhile, referring to Figure 21b , the modular fluid chip 1 connected to another modular fluid chip 2 in the vertical direction (Z-axis direction) may be formed in the following structure: the fluid passage 112 formed in the main body 11 may guide the flow of the fluid to the fluid passages 112 of another modular fluid chip 2 provided on the upper and lower sides of the modular fluid chip 1.
[0293] Referring to Figure 22c and Figure 23c, the modular fluid chip 1 connected to other modular fluid chips 2 in the vertical direction (Z-axis direction) is composed of a main body 11 and a housing 12, and the fluid channel 112 formed in the main body 11 may include a horizontal portion 1121 and a vertical portion 1122. The horizontal portion 1121 is arranged parallel to the second hole 121 formed in the housing 12. The vertical portion 1122 communicates with one end and the other end of the horizontal portion 1121, and bends upward and downward in the vertical direction from the horizontal portion 1121 to communicate with the external space. Here, the main body 11 may include a plurality of coupling units 122 capable of connecting other modular fluid chips 2 provided on the upper and lower sides of the housing 12 to the modular fluid chip 1. Each of the plurality of coupling units 122 may be formed of a magnet having an S pole on one side and an N pole on the other side, and may be installed in the mounting grooves 113 provided on the upper and lower surfaces of the main body 11. Further, the plurality of coupling units 122 may be provided with through holes communicating with each vertical portion 1122 formed in the main body 11. The through holes are formed to correspond to the shape of the vertical portion 1122 and may have the same central axis as the vertical portion 1122.
[0294] Therefore, as Figure 25c shown, when the housing 12 of the modular fluid chip 1 is connected to other modular fluid chips 2 in the horizontal direction or the vertical direction, the fluid channel 112 provided in the modular fluid chip 1 can be aligned and communicated with the fluid channel 112 provided in other modular fluid chips 2.
[0295] In addition, the above-mentioned modular fluid chip 1 may be formed into a structure capable of being connected to other modular fluid chips 2 in a state where the cover 13 is coupled to the housing 12.
[0296] Referring to Figure 22d and Figure 23d , the cover 13 may be provided with an extension hole 132, and the extension hole 132 communicates with the vertical portion 1122 of the fluid channel 112 provided in the main body 11 and communicates with other modular fluid chips 2.
[0297] In addition, the main body 11 and the cover 13 may include a plurality of coupling units 122, and the plurality of coupling units 122 can connect other modular fluid chips 2 provided on the upper and lower sides of the modular fluid chip 1 to the modular fluid chip 1.
[0298] The plurality of coupling units 122 may be formed of a magnet having an S pole on one side and an N pole on the other side, and may be installed in the main body 11 and the cover 13.
[0299] More specifically, the plurality of coupling units 122 may include a first magnetic part 1221, a second magnetic part 1222, and a third magnetic part 1227. The first magnetic part 1221 is mounted on the upper and lower surfaces of the main body 11, the second magnetic part 1222 is mounted on the outer surface of the corresponding cover 13, and the third magnetic part 1227 is mounted on the inner surface of the corresponding cover 13. Here, the third magnetic part 1227 mounted on the inner surface of the cover 13 can be magnetically connected to the first magnetic part 1221 mounted in the main body 11, and the second magnetic part 1222 mounted on the outer surface of the cover 13 can be magnetically connected to the second magnetic part 1222 mounted in the cover 13 of the other modular fluid chip 2. Further, the main body 11 may be provided with a receiving groove 113 for receiving the first magnetic part 1221, and the cover 13 may be provided with receiving grooves 135 for receiving the second magnetic part 1222 and the third magnetic part 1227.
[0300] In addition, a through hole communicating with the vertical part 1122 of the fluid passage 112 provided in the main body 11 may be formed in the first magnetic part 1221. The through hole formed in the first magnetic part 1221 is formed to correspond to the shape of the vertical part 1122 and may have the same central axis as the vertical part 1122. In addition, through holes communicating with the extension hole 132 provided in the cover 13 may be formed in the second magnetic part 1222 and the third magnetic part 1227. The through holes formed in the second magnetic part 1222 and the third magnetic part 1227 may be formed to correspond to the shape of the extension hole 132 and may have the same central axis as the extension hole 132.
[0301] Refer to Figure 24b , in order to further maximize the bonding force between the modular fluid chip 1 and the other modular fluid chip 2, the coupling units 122 in the form of magnets may be further mounted on the upper and lower surfaces of the housing 12.
[0302] Here, the coupling units 122 in the form of magnets may be formed in the shape of a tablet as shown in (a) of Figure 24b , or in the shape of a panel as shown in (b) of Figure 24b , and may be mounted on the upper and lower surfaces of the housing 12. In this case, receiving grooves 123 for receiving the coupling units 122 may be formed in the upper and lower surfaces of the housing 12.
[0303] In addition, the modular fluid chip 1 according to the fourth embodiment of the present disclosure may further include an imaging component 14, a light source 15, and a temperature controller 16.
[0304] Refer to Figure 31, the modular fluid chip 1 may further include an imaging component 14 and a light source 15. The imaging component 14 is disposed on the cover 13 to image the whole or part of the channel through which the fluid flows, and the light source 15 is disposed in the housing 12 or the cover 13 to irradiate predetermined light toward the channel.
[0305] In addition, referring to Figure 32 , the modular fluid chip 1 may further include a temperature controller 16. The temperature controller 16 is installed in the housing 12 or the cover 13 to heat or cool the main body 11 to a preset temperature. For example, a Peltier element or a resistive element may be applied to the temperature controller 16. In contrast, the temperature controller 16 may be formed into a channel structure that directly supplies gas or air at a predetermined temperature to the channel. However, the temperature controller 16 is not limited thereto and may be changed into various structures and shapes for application.
[0306] Furthermore, although not shown in the drawings, the modular fluid chip 1 according to the fourth embodiment of the present disclosure may further include a gas supply component (not shown) and a circulator (not shown).
[0307] The gas supply component may supply gas at a set temperature into the gap between the main body 11 and the housing 12 or between the main body 11 and the cover 13, or supply gas at a set temperature into the interior of the main body 11, so as to heat or cool the main body 11 to a preset temperature.
[0308] The circulator may be connected to the first hole 111 of the main body 11, and may transfer pressure to the first hole 111 and the fluid channel 112 by a pumping action using a pressure difference, so as to stably move the fluid in one direction.
[0309] Hereinafter, the modular fluid chip 1 according to the fifth embodiment of the present disclosure will be described.
[0310] As a reference, for each component used to describe the modular fluid chip 1 according to the fifth embodiment of the present disclosure, for the convenience of description, the same reference numerals as those used when describing the modular fluid chip 1 according to the fourth embodiment of the present disclosure will be used. The same or redundant descriptions will be omitted.
[0311] Referring to Figure 38 and Figure 40 , the modular fluid chip 1 according to the fifth embodiment of the present disclosure includes a main body 11.
[0312] At least one first hole 111 is formed in the main body 11 to guide the fluid flow.
[0313] The first hole 111 communicates with a fluid passage 112 formed inside the main body 11 and a third hole 171 formed in a fluid connector 17, which will be described later, so as to guide the fluid flow in at least one direction of the X-axis direction and the Y-axis direction. Further, the first hole 111 may be formed in a shape corresponding to the third hole 171 formed in the fluid connector 17 and the fluid passage 112 provided in the main body 11.
[0314] In addition, a fluid passage 112 may be formed in the main body 11.
[0315] The fluid passage 112 may communicate with at least one first hole 111 to allow the fluid to flow. In addition, the fluid passage 112 may be configured to perform a preset function on the flowing fluid and guide the fluid flow in various directions.
[0316] In addition, the modular fluid chip 1 according to the fifth embodiment of the present disclosure includes a housing 12.
[0317] Referring to Figure 38 and Figure 40 , the housing 12 is configured to accommodate the main body 11 and the fluid connector 17.
[0318] Furthermore, the housing 12 includes a coupling unit 122.
[0319] The coupling unit 122 may be configured to couple the modular fluid chip 1 to another modular fluid chip 2 in the horizontal direction (X-axis direction and Y-axis direction).
[0320] More specifically, the coupling unit 122 is accommodated in the housing 12 or provided integrally with the housing 12, and can connect the modular fluid chip 1 to another modular fluid chip 2 in the horizontal direction (X-axis direction and Y-axis direction), and at the same time can automatically align and fix the modular fluid chip 1 with another modular fluid chip 2.
[0321] The coupling unit 122 may include a magnetic material.
[0322] More specifically, the coupling unit 122 is formed of a magnetic body having an S pole on one side and an N pole on the other side, and can be installed inside or outside the housing 12.
[0323] In addition, the coupling unit 122 may be formed into a structure capable of directly connecting to the coupling unit 122 provided in another modular fluid chip 2.
[0324] Referring to Figure 26 , the coupling unit 122 provided in the modular fluid chip 1 and the corresponding coupling unit 122 of another modular fluid chip 2 may include corresponding protruding portions 1223 or recessed portions 1224.
[0325] Referring to Figure 27 Figure 27 , the coupling unit 122 provided in the modular fluid chip 1 may include a fastening portion 1225 having a hook shape at one end thereof, so as to be coupled to another modular fluid chip 2. In this case, a fastening groove 1226 corresponding to the fastening portion 1225 provided in the modular fluid chip 1 may be formed in the other modular fluid chip 2.
[0326] Referring to Figure 28 Figure 28 , the coupling unit 122 provided in the modular fluid chip 1 may include a fastening portion 1225 having a bolt shape with a thread on its outer circumferential surface, so as to be coupled to another modular fluid chip 2. In this case, a fastening groove 1226 corresponding to the fastening portion 1225 provided in the modular fluid chip 1 may be formed in the other modular fluid chip 2.
[0327] Referring to Figure 29 Figure 29 , the coupling unit 122 provided in the modular fluid chip 1 may include a fastening portion 1225 in the form of a "∩" shape of a pin, so as to be coupled to another modular fluid chip 2. In this case, a fastening groove 1226 into which the fastening portion 1225 in the form of a pin can be inserted may be formed in a modular fluid chip 2 different from the modular fluid chip 1.
[0328] Referring to Figure 30 Figure 30 , the coupling unit 122 provided in the modular fluid chip 1 may be coupled to another modular fluid chip 2 through a fastening portion 1225 having a bolt shape. In this case, a fastening groove 1226 for fastening the bolt-shaped fastening portion 1225 may be formed in a modular fluid chip 2 different from the modular fluid chip 1.
[0329] In addition, the modular fluid chip 1 according to the fifth embodiment of the present disclosure includes a fluid connector 17.
[0330] Referring to Figure 38 and Figure 40 Figure 40 , the fluid connector 17 may be formed in the form of a sheet or a pad and may be detachably mounted on the housing 12. Here, a mounting groove 123 capable of accommodating the fluid connector 17 may be formed in the housing 12. And, a third hole 171 aligned with the first hole 111 may be formed in the fluid connector 17.
[0331] In addition, the fluid connector 17 may be configured to form an interface when contacting another fluid connector 17.
[0332] More specifically, the fluid connector 17 may be formed of an elastomer material that is elastically deformable, and when contacting another fluid connector 17 provided in the other modular fluid chip 2, an interface is formed at the contact portion. Here, an adhesive layer may be provided on one surface of the fluid connector 17, and when the fluid connector 17 contacts another fluid connector 17, the adhesive layer may adhere to one surface of the other fluid connector 17.
[0333] However, the fluid connector 17 is not limited thereto, and may be changed into various shapes or various materials so as to be applied under the condition of being able to perform the same function. For example, when manufacturing the housing 12, the fluid connector 17 may be integrally provided on the outer surface of the housing 12 by double injection molding, and may be formed into a circular or polygonal annular shape having a hole formed in the center, or may be formed into a plate-shaped plug shape. Additionally, the fluid connector 17 may be formed of at least one of a polymer resin, an amorphous material, and a metal, and may include at least one of chlorinated polyethylene, dimethyl ethylene propylene, silicone rubber, acrylic resin, amide resin, epoxy resin, phenolic resin, polyester-based resin, polyvinyl resin, ethylene propylene rubber, polyvinyl butyral resin, polyurethane resin, and nitrile-based rubber.
[0334] Therefore, when the modular fluid chip 1 is connected to another modular fluid chip 2, the fluid connector 17 provided in the modular fluid chip 1 is in close contact with the fluid connector 17 provided in the other modular fluid chip 2 to form an interface. Thus, the connection portion between the modular fluid chip 1 and the other modular fluid chip 2 can be completely airtight, thereby preventing fluid leakage.
[0335] In addition, the fluid connector 17 may be provided on at least one of the outside and the inside of the housing 12.
[0336] Refer to Figure 42 , the fluid connector 17 provided outside the housing 12 can be in close contact with another fluid connector 17 to form an interface, and the fluid connector 17 provided inside the housing 12 can be in close contact with the main body 11 to form an interface.
[0337] Furthermore, the fluid connector 17 may be formed into a structure capable of being coupled to the housing 12.
[0338] Refer to Figure 38 and Figure 40, a protruding portion 173 having a protrusion shape may be formed on the fluid connector 17, and the protruding portion 173 protrudes from the outer surface of the fluid connector 17 by a predetermined length and is inserted into the seating groove 123 formed in the housing 12. Accordingly, the fluid connector 17 is more stably coupled to the housing 12 to restrict the movement of the housing 12. In addition, even when the modular fluid chip 1 is coupled to another modular fluid chip 2, it is feasible to prevent the fluid connector 17 from being separated from the housing 12.
[0339] Meanwhile, although not shown in the drawings, a recessed portion having a groove shape may be formed in the fluid connector 17, and the recessed portion may be recessed from the outer surface of the fluid connector 17 by a predetermined depth and may be coupled to a protrusion formed in the housing 12.
[0340] However, the coupling structure provided in the fluid connector 17 does not have to be limited thereto, and may be changed into various shapes for application.
[0341] In addition, the fluid connector 17 may be formed into a structure capable of directly communicating with the main body 11 to be connected to another modular fluid chip 2.
[0342] Referring to Figure 40 , the fluid connector 17 is accommodated in the housing 12, but may pass through the housing 12 to be in close contact with the outer surface of the main body 11. Accordingly, the third hole 171 provided in the fluid connector 17 directly communicates with the first hole 111 provided in the main body 11 and allows fluid to flow.
[0343] That is, the fluid connector 17 installed through the housing 12 is in close contact with the fluid connector 17 of another modular fluid chip 2 on one side thereof to form an interface, and is in close contact with the outer surface of the main body 11 on the other side thereof to form an interface, thereby minimizing points where fluid may leak. Accordingly, stable fluid flow may be allowed.
[0344] For example, the fluid connector 17 may include a seating portion 172 and a protruding portion 173. The seating portion 172 is seated in the seating groove 123 formed in the outer surface of the housing 12 and is connected to another modular fluid chip 2. The protruding portion 173 protrudes from one surface of the seating portion 172 by a predetermined length to pass through the housing 12 and is in close contact with the outer surface of the main body 11 to form an interface. Here, a recessed portion 1231 may be provided in the inner surface of the housing 12, and the recessed portion 1231 is formed to correspond to the shape of the outer surface of the protruding portion 173 and supports the protruding portion 173.
[0345] In addition, while directly communicating with the main body 11, the fluid connector 17 may be formed into a structure in which the fluid connector 17 is divided into multiple parts.
[0346] Reference Figure 41 and Figure 42 As shown in FIGS. 1 and 2, the fluid connector 17 may include a mounting portion 172, a protruding portion 173, and an O-ring 174.
[0347] The mounting portion 172 may be disposed in a mounting groove 123 formed in the outer surface of the housing 12, and may be in close contact with the other modular fluid chip 2 to form an interface.
[0348] The protruding portion 173 may be separated from the mounting portion 172, and may be received in a recessed portion 1231 provided inside the housing 12, and may be in close contact with the outer surface of the main body 11 and form an interface.
[0349] The O-ring 174 is disposed between the mounting portion 172 and the protruding portion 173 to connect the mounting portion 172 and the protruding portion 173 to each other, and when connecting the modular fluid chip 1 and the other modular fluid chip 2, the load acting on the fluid connector 17 in the axial direction is evenly distributed, thereby preventing the mounting portion 172 or the protruding portion 173 from deforming. For example, the O-ring 174 is formed of an elastomer, plastic, or metal material, and another hole communicating with a third hole 171 formed in the mounting portion 172 and the protruding portion 173 may be formed inside the O-ring 174.
[0350] However, the fluid connector 17 is not limited thereto, and may be changed into various forms for application.
[0351] Hereinafter, the modular fluid chip 1 according to the sixth embodiment of the present disclosure will be described.
[0352] As a reference, for each component for describing the modular fluid chip 1 according to the sixth embodiment of the present disclosure, for convenience of description, the same reference numerals as those used when describing the modular fluid chip 1 according to the fourth embodiment of the present disclosure will be used. The same or redundant descriptions will be omitted.
[0353] Reference Figure 13 and Figure 17 As shown in FIGS. 3 and 4, the modular fluid chip 1 according to the sixth embodiment of the present disclosure includes a main body 11.
[0354] At least one first hole 111 is formed in the main body 11 to guide fluid flow.
[0355] The first hole 111 communicates with a second hole 121 of a housing 12 and a fluid passage 112 formed inside the main body 11, which will be described later, so as to guide fluid flow in at least one of the X-axis direction and the Y-axis direction. Additionally, the first hole 111 may be formed in a shape corresponding to the second hole 121 provided in the housing 12 and the fluid passage 112 provided in the main body 11.
[0356] Additionally, a fluid passage 112 may be formed in the main body 11.
[0357] The fluid passage 112 may communicate with at least one first hole 111 to allow fluid flow. Additionally, the fluid passage 112 may be configured to perform a preset function on the flowing fluid and guide fluid flow in various directions.
[0358] Additionally, a modular fluid chip 1 according to a sixth embodiment of the present disclosure includes a housing 12.
[0359] The housing 12 is formed in a frame structure having an accommodation space formed therein, and the housing 12 is configured to accommodate the main body 11. Additionally, a second hole 121 is formed in the housing 12, and when the main body 11 is accommodated in the accommodation space, the second hole 121 corresponds to at least one first hole 111 provided in the main body 11 and allows fluid flow.
[0360] Additionally, the housing 12 includes a fluid connector 17.
[0361] The fluid connector 17 is configured to connect the modular fluid chip 1 to other modular fluid chips 2.
[0362] Referring to Figure 33 and Figure 34 , the fluid connector 17 may be formed in the form of a sheet or a pad and may be detachably mounted on the outer surface of the housing 12. Here, a mounting groove 123 corresponding to the fluid connector 17 may be formed in the outer surface of the housing 12 for mounting the fluid connector 17. And a third hole 171 aligned with the first hole 111 and the second hole 121 may be formed in the fluid connector 17.
[0363] Additionally, referring to Figure 35 and Figure 36 , the fluid connector 17 may be configured to form an interface when contacting another fluid connector 17.
[0364] More specifically, the fluid connector 17 can be formed of an elastomer material that is elastically deformable, and when contacting another fluid connector 17, an interface is formed at the contact portion. Here, an adhesive layer can be provided on one surface of the fluid connector 17, and when the fluid connector 17 contacts another fluid connector 17, the adhesive layer can adhere to one surface of the other fluid connector 17.
[0365] However, the fluid connector 17 is not limited thereto, and can be changed into various shapes or various materials, and thus can be applied under the condition of being able to perform the same function. For example, when manufacturing the housing 12, the fluid connector 17 can be integrally provided on the outer surface of the housing 12 by double injection molding, and can be formed into a circular or polygonal annular shape with a hole formed in the center, or can be formed into a plate-shaped plug shape. In addition, the fluid connector 17 can be formed of at least one of a polymer resin, an amorphous material, and a metal, and can include at least one of chlorinated polyethylene, dimethyl ethylene propylene, silicone rubber, acrylic resin, amide resin, epoxy resin, phenolic resin, polyester-based resin, polyvinyl resin, ethylene propylene rubber, polyvinyl butyral resin, polyurethane resin, and nitrile-based rubber.
[0366] Therefore, when the modular fluid chip 1 is connected to another modular fluid chip 2 in the horizontal or vertical direction, the fluid connector 17 provided in the modular fluid chip 1 is in close contact with the fluid connector 17 provided in the other modular fluid chip 2 and forms an interface. Thus, the connection portion between the modular fluid chip 1 and the other modular fluid chip 2 can be completely airtight, thereby preventing fluid leakage. Here, a coupling unit 122 having magnetism to maximize the adhesive force of the fluid connector 17 can be further provided on the inner surfaces of the corresponding housings 12 provided in the modular fluid chip 1 and the other modular fluid chip 2.
[0367] In addition, the fluid connector 17 can be provided on at least one of the outside and inside of the housing 12.
[0368] Refer to Figure 37 , the fluid connector 17 provided outside the housing 12 can be in close contact with another fluid connection member 17 and form an interface, and the fluid connector 17 provided inside the housing 12 can be in close contact with the main body 11 and form an interface.
[0369] Furthermore, the fluid connector 17 can be formed into a structure capable of being coupled to the housing 12.
[0370] Refer to Figure 38 and Figure 39, a protruding portion 173 having a protruding shape may be formed on the fluid connector 17, and the protruding portion 173 protrudes from the outer surface of the fluid connector 17 by a predetermined length and is inserted into a seating groove 123 formed in the housing 12.
[0371] Meanwhile, although not shown in the drawings, a recessed portion having a groove shape may be formed in the fluid connector 17, and the recessed portion may be recessed from the outer surface of the fluid connector 17 by a predetermined depth and may be coupled to a protrusion formed in the housing 12.
[0372] However, the coupling structure provided in the fluid connector 17 does not have to be limited thereto and may be changed into various shapes for application.
[0373] In addition, the fluid connector 17 may be formed into a structure capable of directly communicating with the main body 11 to be connected to another modular fluid chip 2.
[0374] Refer to Figure 40 , the fluid connector 17 is accommodated in the housing 12, but may pass through the housing 12 to be in close contact with the outer surface of the main body 11. Accordingly, a third hole 171 provided in the fluid connector 17 directly communicates with a first hole 111 provided in the main body 11 and allows fluid to flow.
[0375] That is, the fluid connector 17 installed by passing through the housing 12 is in close contact with the fluid connector 17 of another modular fluid chip 2 on one side thereof to form an interface, and is in close contact with the outer surface of the main body 11 on the other side thereof to form an interface, thereby minimizing points where fluid may leak. Thus, stable fluid flow may be allowed.
[0376] In addition, while directly communicating with the main body 11, the fluid connector 17 may be formed into a structure in which the fluid connector 17 is divided into multiple parts.
[0377] Refer to Figure 41 and Figure 42 , the fluid connector 17 may include a seating portion 172, a protruding portion 173, and an O-ring 174.
[0378] The seating portion 172 may be seated in a seating groove 123 formed in the outer surface of the housing 12 and may be in close contact with another modular fluid chip 2 to form an interface.
[0379] The protruding portion 173 may be separated from the seating portion 172 and is accommodated in a recessed portion 1231 provided inside the housing 12 and may be in close contact with the outer surface of the main body 11 to form an interface.
[0380] An O-ring 174 is disposed between the placement portion 172 and the protruding portion 173 to connect the placement portion 172 and the protruding portion 173 to each other, and when connecting the modular fluid chip 1 and other modular fluid chips 2, evenly distribute the load acting on the fluid connector 17 in the axial direction, thereby preventing the placement portion 172 or the protruding portion 173 from deforming.
[0381] In addition, the modular fluid chip 1 according to the sixth embodiment of the present disclosure may further include at least one sensor 18.
[0382] Referring to Figure 43 , at least one sensor 18 is installed inside the main body 11 in which the fluid channel 112 is formed and is connected to the fluid channel 112 through a microchannel. When fluid flows in the fluid channel 112, at least one sensor 18 can detect a signal generated by the fluid.
[0383] Here, at least one sensor 18 may be configured to detect at least one of an electrical signal, a fluorescence signal, an optical signal, an electrochemical signal, a chemical signal, and a spectral signal.
[0384] In addition, at least one sensor 18 may be formed of any one of a metal, an organic-inorganic composite material, and an organic conductor.
[0385] More specifically, at least one sensor 18 may be formed of a metal electrode including at least one material of Au, Mg, Ti, Cr, Mn, Fe, Co, Ni, Cu, Zn, Ga, Al, Zr, Nb, Mo, Ru, Ag, and Sn, may be formed of an organic electrode including at least one material of a conductive polymer and carbon, or may be formed of an organic-inorganic composite electrode in which at least one material of the materials constituting the metal electrode is mixed with at least one material of the materials constituting the organic electrode.
[0386] In addition, at least one sensor 18 may be formed of a material having transparency in order to detect at least one of a fluorescence signal, an optical signal, and a spectral signal.
[0387] For example, as shown in (a) of Figure 43 , at least one sensor 18 may include an electrode installed inside the main body 11 and connected to the fluid channel 112, and a USB port (USBPORT) electrically connected to the electrode and connectable from the outside through a USB connector. In addition, as Figure 43As shown in (b) thereof, at least one sensor 18 may include: a plurality of electrodes installed inside the main body 11 and connected to the fluid channel 112 at multiple positions; contact pads connected to the plurality of electrodes; a plurality of communication holes formed in the cover 13 to communicate the external space with the plurality of contact pads; fixing pins inserted into the plurality of communication holes and contacting the plurality of contact pads; and a contact line connecting the fixing pins and an external connection device (contact device) to each other and transmitting a signal sensed through the fixing pins to the external connection device. However, at least one sensor 18 is not limited thereto and may be changed in various forms for application.
[0388] Hereinafter, a fluid flow system 1000 including a modular fluid chip according to an embodiment of the present disclosure (hereinafter, referred to as "fluid flow system 1000") will be described.
[0389] As a reference, for each component used to describe the fluid flow system 1000, for ease of description, the same reference numerals as those used in the drawings when describing the modular fluid chip 1 according to the first embodiment of the present disclosure will be used. The same or redundant descriptions will be omitted.
[0390] Referring to Figure 1 and Figure 2 , the fluid flow system 1000 is a fluid flow system 1000 for molecular diagnosis, capable of performing processes of collecting a sample from a fluid such as body fluid or blood, extracting a gene from the collected sample, amplifying using polymerase chain reaction, and analyzing. The fluid flow system 1000 includes a first modular fluid chip 1 and at least one second modular fluid chip 2. The first modular fluid chip 1 is capable of implementing a first function, and at least one second modular fluid chip 2 is capable of implementing a second function different from the first function and is connected to the first modular fluid chip 1 in at least one of the horizontal direction and the vertical direction. Here, the second modular fluid chip 2 does not necessarily implement a function different from that of the first modular fluid chip 1 and may be applied as needed to implement the same function as the first modular fluid chip 1.
[0391] As described above, according to an embodiment of the present disclosure, a fluid chip capable of performing one function is formed in a modular form, whereby fluid flow systems 1000 with various structures can be implemented by connecting a plurality of fluid chips capable of performing different functions as needed, without limitation in shape or size. Thus, various accurate experimental data can be obtained, and when a specific part is deformed or damaged, only the corresponding fluid chip can be replaced, thereby reducing manufacturing and maintenance costs.
[0392] In addition, the housing 12 that can be connected to another modular fluid chip 2 and the main body 11 in which fluid channels 112 are formed and which is selectively replaceable in the housing 12 are both formed in a modular shape. Therefore, it is feasible to easily change the position of a selected section and the shape of the fluid channels in a fluid flow system 1000 as needed. Thus, compared with the fluid flow system 1000 according to the prior art, it is feasible to quickly change the experimental conditions, allowing various experiments to be carried out within a preset time period, and when a component is defective or damaged, it is possible to quickly replace only the housing 12 or the main body 11 corresponding to that component.
[0393] In addition, when the modular fluid chip 1 and other modular fluid chips 2 are connected, the holes of the corresponding fluid chips are aligned and communicate with each other, and at the connection portion of the modular fluid chip 1 and other modular fluid chips 2, fluid connectors 17 that are in close contact with each other and form an interface are provided. Therefore, fluid leakage at the connection portion during fluid flow is prevented, and changes in fluid pressure are minimized. In addition, the composition of the fluid or the shape of the droplets can be maintained.
[0394] In the foregoing, preferred embodiments of the present disclosure have been shown and described, but the present disclosure is not limited to the above specific embodiments, and those skilled in the art will understand that various modifications can be made without departing from the scope and spirit of the invention disclosed in the appended claims. These modifications should not be understood separately from the technical spirit or expectations of the present disclosure.
[0395] [National Research and Development Project Supporting the Present Invention]
[0396] Subject Inherent Number: 2017M3A7B4039936
[0397] Deployment Name: Ministry of Science and ICT
[0398] Research Management Professional Institution: Korea Research Foundation
[0399] Research Project Name: Development Project of Nanomaterial Source Technology
[0400] Research Subject Name: Development of Basic Technology for Modular Sources of Electro-Nano Biosensors and Quasi-Mass Production Module Chips
[0401] Contribution Rate: 80 / 100
[0402] Administrative Agency: Nano Fusion Technology Institute
[0403] Research Period: February 1, 2019 to December 31, 2019
[0404] [National Research and Development Project Supporting the Present Invention]
[0405] Project ID: 2014R1A5A201008
[0406] Department Name: Ministry of Science, Technology and Information Technology
[0407] Professional institution for research management: Korea Research Foundation
[0408] Research Project Name: Leading Research Center Project (Basic Medical Research Field (MRC))
[0409] Research topic: Development and manufacturing of basic technology of nanobiochips
[0410] Contribution rate: 20 / 100
[0411] Supervisory institution: Keimyung University
[0412] Research period: March 1, 2019 to February 28, 2020
Claims
1. A modular fluid chip, comprising: a core member that forms at least one flow channel inside; a housing configured to accommodate the core member inside; at least one connection member that is accommodated in the housing and contacts the core member, and when the housing is connected to another modular fluid chip, enables the flow channel to communicate with the flow channel provided in the other modular fluid chip; and a coupling portion that is provided in the housing and, when connected to the other modular fluid chip, connects the housing to the other modular fluid chip and aligns the connection member and the flow channel provided in the other modular fluid chip with each other, wherein the connection member is formed of an elastic material and is configured to open the flow channel by compressing axially and simultaneously expanding in a direction perpendicular to the axial direction when the connection member is axially pressured by being connected to the other modular fluid chip on one side of the connection member, and is configured to close the flow channel by elastic force recovery when the pressure is released.
2. The modular fluid chip according to claim 1, wherein a plurality of the coupling portions are provided and, when connected to the other modular fluid chip, are connected to the other modular fluid chip at different positions from each other, and the connection member is disposed between the plurality of coupling portions.
3. The modular fluid chip according to claim 2, wherein the connection member is configured to be integrally provided on the core member or to be connectable and separable from the core member.
4. The modular fluid chip according to claim 2, wherein the connection member is configured to open the flow channel provided inside the connection member when connected to the other modular fluid chip and to close the flow channel when separated from the other modular fluid chip.
5. The modular fluid chip according to claim 1, wherein on the inner surface of the connection member, an opening and closing portion is provided, and the opening and closing portion contacts or separates from each other according to the deformation of the connection member, thereby closing and opening the flow channel.
Citation Information
Patent Citations
Fluidic connectors and microfluidic systems
CN101754812A
Modular microfluidic system and method for building a modular microfluidic system
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