Observation Chamber for Mesenchymal Stem Cell Treatment of Inflammatory Bowel Disease Mouse Model
By designing lift protection components and cleaning and scraping components in the experimental observation bin, the pollution problem of the inner wall of the observation bin caused by the restlessness of the experimental mice was solved, and more efficient use of the observation bin and more accurate experimental observation was achieved.
Patent Information
- Application Number
- CN202311041566.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-08-18
- Publication Date
- 2025-06-24
- Estimated Expiration
- 2043-08-18
AI Technical Summary
The experimental mice in the experimental observation bin may experience restlessness, which will lead to contamination on the inner wall of the observation bin, which will affect the accuracy of the experimental observation and reduce the efficiency of the observation bin.
A model observation chamber for the treatment of inflammatory bowel disease in mice was designed, including lifting protection components and cleaning and scraping components. The lifting rack drives the protective plate and cleaning and scraping components for automatic cleaning and protection, to prevent the experimental mice from causing scratches and contamination on the inner wall of the observation chamber.
It effectively prevents scratches and contamination of the inner wall of the observation chamber by experimental mice, and improves the efficiency of the observation chamber and the accuracy of experimental observation.
Smart Images

Figure CN116831041B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of experimental observation chambers, and particularly to an observation chamber for treating inflammatory bowel disease mouse models with mesenchymal stem cells. Background Art
[0002] Mice are commonly used animals in biomedical experiments. Due to their extremely similar characteristics to the human genome, high reproductive rate, high survival rate, and easy breeding, they are widely used in scientific experiments. When experimental mice are in the observation chamber, they may become restless, resulting in contamination of the inner wall of the observation chamber. Since the experimental mice inside the observation chamber generally cannot contact the external environment, manual cleaning of the inner wall of the observation chamber cannot be carried out in a timely manner. If not cleaned for a long time, it may affect the experimental observation, leading to misjudgment in the experimental observation. If the experimental mice scratch the observation chamber due to stress, it is easy to reduce the service efficiency of the observation chamber. At the same time, dirt is likely to remain on the scratches, which will also affect the experimental observation and judgment.
[0003] Therefore, an observation chamber for treating inflammatory bowel disease mouse models with mesenchymal stem cells is proposed. Summary of the Invention
[0004] The purpose of the present invention is to provide an observation chamber for treating inflammatory bowel disease mouse models with mesenchymal stem cells to solve the problems raised in the above background art.
[0005] To achieve the above purpose, the present invention provides the following technical solution: An observation chamber for treating inflammatory bowel disease mouse models with mesenchymal stem cells, including an observation chamber. A cover plate is hinged to the top of the observation chamber. A fixed platform is fixedly connected inside the observation chamber. A lifting and protecting component is arranged inside the observation chamber. A cleaning and scraping component for cleaning the inner wall of the observation chamber is arranged at the top of the lifting and protecting component. Rotating and switching components for controlling the rotation of the cleaning and scraping component are arranged on both sides of the cleaning and scraping component. A detection and control component for controlling the lifting of the lifting and protecting component is arranged inside the fixed platform.
[0006] Preferably, the lifting and protecting component includes a first lifting groove, a first stabilizing rod, an electro-hydraulic rod, a lifting frame, a first recovery groove, and a protection plate. The first lifting groove is opened on the inner wall of the observation chamber. The first stabilizing rod is fixedly connected inside the first lifting groove. The bottom of the electro-hydraulic rod is fixedly connected inside the observation chamber. The output end of the top of the electro-hydraulic rod is fixedly connected to the lower surface of the lifting frame. The bottom of the lifting frame is movably connected inside the first lifting groove. The bottom of the lifting frame is movably connected to the outer wall of the first stabilizing rod. The first recovery groove is opened on the fixed platform. The upper end of the protection plate is fixedly connected to the inside of the lifting frame. The protection plate is movably connected inside the first recovery groove.
[0007] Preferably, the cleaning and scraping assembly includes a lifting block, a rotating rod, a fixed shaft, a scraper and a cleaning strip, the lifting block is fixedly connected to the upper surface of the lifting frame, the rotating rod is rotatably connected to the middle part of the lifting block, the inner end of the rotating rod is fixedly connected to the outer end of the fixed shaft, the outer side of the fixed shaft is fixedly connected with a scraper for scraping moisture off the inner wall of the observation bin, and the inner side of the fixed shaft is fixedly connected with a cleaning strip for cleaning dust off the inner wall of the observation bin.
[0008] Preferably, the rotation switching assembly includes a limit block, a second lifting slot, a second stabilizing bar, a lifting block and a limit slot, the limit block is fixedly connected to the outer side of the lifting block, the second lifting slot is opened on the inner wall of the observation bin, the second stabilizing bar is fixedly connected to the inside of the second lifting slot, the lifting block is movably connected to the outer side of the limit block through the limit slot, the outer lower end of the lifting block is movably connected to the outer wall of the second stabilizing bar, and the limit slot is opened on the inner surface of the lifting block.
[0009] Preferably, the rotation switching assembly also includes a stop block, a first spring and a magnetic block, the stop block is fixedly connected to the bottom of the second lifting slot, the top of the first spring is fixedly connected to the top of the second lifting slot, the bottom of the first spring is fixedly connected to the upper surface of the magnetic block, and the magnetic block is movably connected to the outer wall of the second stabilizing rod.
[0010] Preferably, the rotation switching assembly also includes a control groove, a rotation plate and a control rod, the control groove is opened through the lifting block, one end of the rotation plate is fixedly connected to the outer end of the rotation rod, the other end of the rotation plate is fixedly connected to the inner end of the control rod, and the outer end of the control rod is movably connected to the inside of the control groove.
[0011] Preferably, the detection and control assembly includes a fixed frame, a support rod, a second recovery groove, a second spring, a support plate, an electric contact rod and a detection groove, the fixed frame is fixedly connected to the interior of the observation bin, the middle lower surface of the fixed frame is fixedly connected to the top of the support rod, the second recovery groove is opened on the upper surface of the fixed table, the bottom of the second spring is fixedly connected to the interior of the second recovery groove, the top of the second spring is fixedly connected to the lower surface of the support plate, the electric contact rod is fixedly connected to the bottom of the support plate, the detection groove is opened on the fixed table, and the bottom of the electric contact rod abuts against the detection groove.
[0012] Preferably, the lower end of the lifting block is made of magnetic material to facilitate magnetic attraction by the magnetic block, and the shape of the control groove is set to an inclined "V" shape to enable the rotating plate to drive the rotating rod to rotate through the control rod.
[0013] Preferably, the electric contact rod is electrically connected to the electro-hydraulic rod. The electric contact rod can control the extension of the electro-hydraulic rod. The bottom of the electric contact rod is provided with a telescopic structure to ensure that the electric contact rod is always in contact with the detection groove. The detection groove is electrically connected to the power supply of the device to control the circuit of the device.
[0014] Compared with the prior art, the beneficial effects of the present invention are as follows:
[0015] 1. The observation chamber for treating inflammatory bowel disease mouse models with mesenchymal stem cells in the present invention can drive the protective plate to move upward from the inside of the first recovery groove through the lifting frame. The rising protective plate can block the experimental mice to prevent scratches on the inner wall of the observation chamber when the experimental mice are restless, thereby reducing the problem of scratches on the observation chamber affecting subsequent use, improving the observation efficiency of the device, and preventing scratches from affecting the observation of the experimental mice.
[0016] 2. The observation chamber for treating inflammatory bowel disease mouse models with mesenchymal stem cells in the present invention can be in contact with the bottom of the lifting block through the lifting frame. The lifting frame pushes the lifting block upward, and the fixed shaft moves upward synchronously. The fixed shaft drives the cleaning strip to clean the inner wall of the observation chamber, thereby cleaning the dust on the inner wall of the observation chamber, preventing the dust from affecting the use of the observation chamber, preventing the dust from affecting the observation of the experimental mice, and ensuring the effectiveness of the observation of the experimental mice.
[0017] 3. The observation chamber for treating inflammatory bowel disease mouse models with mesenchymal stem cells in the present invention can clean the dust on the inner wall of the observation chamber by driving the scraper through the fixed shaft, preventing the problem that the upper end of the inner wall of the observation chamber cannot be cleaned. At the same time, after cleaning the dust downward, it can be collected, and the water vapor on the inner wall of the observation chamber can also be scraped off to prevent the problem that the water vapor makes the inner wall of the observation chamber blurred.
[0018] 4. The observation chamber for treating inflammatory bowel disease mouse models with mesenchymal stem cells in the present invention can quickly slide the bottom of the electric contact rod inside the detection groove. The rapid sliding on the detection groove can make the electric contact rod energized, thereby realizing the rapid detection of the state of the experimental mice, and being able to judge the restlessness of the experimental mice in time according to the movement amplitude of the experimental mice. The sensitivity of the device is improved through the universal connection, preventing the problem of jamming during device detection. BRIEF DESCRIPTION OF THE DRAWINGS
[0019] Figure 1 is a three-dimensional schematic diagram of the overall structure of the present invention;
[0020] Figure 2 is a partial three-dimensional schematic diagram of the internal structure of the present invention;
[0021] Figure 3 is a sectional three-dimensional schematic diagram of the internal structure of the present invention;
[0022] Figure 4 For the present invention Figure 3 A schematic diagram of the structure enlargement in the middle;
[0023] Figure 5 It is a three-dimensional schematic diagram of the positional relationship between the control rod, the rotating plate, the rotating rod and the fixed shaft of the present invention;
[0024] Figure 6 For the present invention Figure 5 A magnified schematic diagram of the structure at B in the middle;
[0025] Figure 7 It is a partial three-dimensional schematic diagram of the internal structure of the second lifting tank of the present invention;
[0026] Figure 8 For the present invention Figure 7 A magnified schematic diagram of the structure at C in the middle;
[0027] Figure 9 It is a partial three-dimensional schematic diagram of the connection relationship between the lifting frame and the protective plate of the present invention;
[0028] Figure 10 It is a three-dimensional schematic diagram of the peripheral structure of the control tank of the present invention;
[0029] Figure 11 For the present invention Figure 10 A schematic diagram of the structure at point D is shown in the figure.
[0030] In the figure:
[0031] 1. Observation chamber; 2. Cover plate; 3. Fixed platform;
[0032] 4. Lifting protection assembly; 401. First lifting slot; 402. First stabilizing bar; 403. Electric hydraulic rod; 404. Lifting frame; 405. First recovery slot; 406. Protection plate;
[0033] 5. Cleaning and scraping assembly; 501. lifting block; 502. rotating rod; 503. fixed shaft; 504. scraper; 505. cleaning strip;
[0034] 6. Rotation switching assembly; 601. Limit block; 602. Second lifting slot; 603. Second stabilizing rod; 604. Lifting block; 605. Limit slot; 606. Control slot; 607. Rotation plate; 608. Control rod; 609. Stop block; 610. First spring; 611. Magnetic block;
[0035] 7. Detection control assembly; 701. Fixing frame; 702. Support rod; 703. Second recovery slot; 704. Second spring; 705. Support plate; 706. Electric contact rod; 707. Detection slot. DETAILED DESCRIPTION
[0036] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.
[0037] Please refer to Figures 1 to 11 , the present invention provides a technical solution:
[0038] Embodiment 1
[0039] Please refer to Figures 1 to 11 As shown, the observation chamber for the mesenchymal stem cell treatment of the inflammatory bowel disease mouse model includes an observation chamber 1. A cover plate 2 is hinged to the top of the observation chamber 1. A fixed platform 3 is fixedly connected inside the observation chamber 1. A lifting protection component 4 is arranged inside the observation chamber 1. A cleaning and scraping component 5 for cleaning the inner wall of the observation chamber 1 is arranged on the top of the lifting protection component 4. Rotating and switching components 6 for controlling the rotation of the cleaning and scraping component 5 are arranged on both sides of the cleaning and scraping component 5. A detection and control component 7 for controlling the lifting of the lifting protection component 4 is arranged inside the fixed platform 3.
[0040] During operation, after opening the cover plate 2, the experimental mouse is placed on the detection and control component 7. After closing the cover plate 2, the experimental mouse is observed. If the experimental mouse shows restlessness, at this time, due to the weight of the experimental mouse, the detection and control component 7 deflects, and then the control circuit is powered on. At this time, after the lifting protection component 4 is powered on, it moves upward to block the experimental mouse to prevent the experimental mouse from scratching the inner wall of the observation chamber 1. The lifting protection component 4 drives the cleaning and scraping component 5 to move upward. The cleaning and scraping component 5 flips under the action of the rotating and switching component 6. The continuous upward movement of the lifting protection component 4 can drive the cleaning and scraping component 5 to clean the inner wall of the observation chamber 1. When the cleaning and scraping component 5 moves to the highest position, if the restlessness of the experimental mouse stops at this time, then the detection and control component 7 returns to the normal position. After the lifting protection component 4 is powered off, it retracts downward. The lifting protection component 4 drives the cleaning and scraping component 5 to move downward. The cleaning and scraping component 5 flips again under the action of the rotating and switching component 6. When the lifting protection component 4 continuously moves downward, the inner wall of the observation chamber 1 can be scraped and cleaned through the cleaning and scraping component 5.
[0041] Embodiment 2
[0042] Please refer to Figure 2 , Figure 3 , Figures 5 to 11As shown, the lifting protection component 4 includes a first lifting groove 401, a first stabilizing rod 402, an electro-hydraulic rod 403, a lifting frame 404, a first recovery groove 405, and a protection plate 406. The first lifting groove 401 is opened on the inner wall of the observation chamber 1. The first stabilizing rod 402 is fixedly connected inside the first lifting groove 401. The bottom of the electro-hydraulic rod 403 is fixedly connected inside the observation chamber 1. The output end at the top of the electro-hydraulic rod 403 is fixedly connected to the lower surface of the lifting frame 404. The bottom of the lifting frame 404 is movably connected inside the first lifting groove 401 and is also movably connected to the outer wall of the first stabilizing rod 402. The first recovery groove 405 is opened on the fixed platform 3. The upper end of the protection plate 406 is fixedly connected to the inner side of the lifting frame 404, and the protection plate 406 is movably connected inside the first recovery groove 405.
[0043] The cleaning and scraping component 5 includes a lifting block 501, a rotating rod 502, a fixed shaft 503, a scraping plate 504, and a cleaning strip 505. The lifting block 501 is fixedly connected to the upper surface of the lifting frame 404. The rotating rod 502 is rotatably connected to the middle of the lifting block 501. The inner end of the rotating rod 502 is fixedly connected to the outer end of the fixed shaft 503. A scraping plate 504 for scraping moisture on the inner wall of the observation chamber 1 is fixedly connected to the outside of the fixed shaft 503, and a cleaning strip 505 for cleaning dust on the inner wall of the observation chamber 1 is fixedly connected to the inside of the fixed shaft 503.
[0044] The rotating and switching component 6 includes a limiting block 601, a second lifting groove 602, a second stabilizing rod 603, a lifting block 604, a limiting groove 605, a resisting block 609, a first spring 610, and a magnetic block 611. The limiting block 601 is fixedly connected to the outside of the lifting block 501. The second lifting groove 602 is opened on the inner wall of the observation chamber 1. The second stabilizing rod 603 is fixedly connected inside the second lifting groove 602. The lifting block 604 is movably connected to the outside of the limiting block 601 through the limiting groove 605. The lower end of the lifting block 604 is made of a magnetically conductive material, which is convenient for being magnetically attracted by the magnetic block 611. The outer lower end of the lifting block 604 is movably connected to the outer wall of the second stabilizing rod 603. The limiting groove 605 is opened on the inner surface of the lifting block 604. The resisting block 609 is fixedly connected to the bottom of the second lifting groove 602. The top of the first spring 610 is fixedly connected to the top of the second lifting groove 602, and the bottom of the first spring 610 is fixedly connected to the upper surface of the magnetic block 611. The magnetic block 611 is movably connected to the outer wall of the second stabilizing rod 603.
[0045] The rotation switching assembly 6 also includes a control groove 606, a rotating plate 607 and a control rod 608. The control groove 606 is opened through the lifting block 604. The shape of the control groove 606 is set to an inclined "V" shape, which enables the rotating plate 607 to drive the rotating rod 502 to rotate through the control rod 608. One end of the rotating plate 607 is fixedly connected to the outer end of the rotating rod 502, and the other end of the rotating plate 607 is fixedly connected to the inner end of the control rod 608. The outer end of the control rod 608 is movably connected to the inside of the control groove 606.
[0046] Embodiment 3
[0047] Please refer to Figure 2 , Figure 3 and Figure 4 As shown, the detection control component 7 includes a fixed frame 701, a support rod 702, a second recovery groove 703, a second spring 704, a support plate 705, an electric contact rod 706 and a detection groove 707. The fixed frame 701 is fixedly connected to the inside of the observation chamber 1, the lower surface of the middle part of the fixed frame 701 is fixedly connected to the top of the support rod 702, the second recovery groove 703 is opened on the upper surface of the fixed platform 3, the bottom of the second spring 704 is fixedly connected to the inside of the second recovery groove 703, the top of the second spring 704 is fixedly connected to the lower surface of the support plate 705. Fixed connection, the electric contact rod 706 is fixedly connected to the bottom of the support plate 705, the electric contact rod 706 is electrically connected to the electric hydraulic rod 403, the electric contact rod 706 can control the extension of the electric hydraulic rod 403, the bottom of the electric contact rod 706 is arranged as a telescopic structure, so that the electric contact rod 706 and the detection groove 707 are always in contact, the detection groove 707 is opened on the fixed platform 3, the bottom of the electric contact rod 706 is in contact with the detection groove 707, the detection groove 707 is electrically connected to the power supply used by the equipment, and plays a role in controlling the equipment circuit.
[0048] Overall working principle: In the initial state, the electro-hydraulic rod 403 is powered off. At this time, the electro-hydraulic rod 403 is in a contracted state. The electro-hydraulic rod 403 drives the lifting frame 404 to be in the lowest position. The lifting frame 404 drives the protective plate 406 to be inside the first recovery groove 405. The bottom ends of both sides of the lifting frame 404 are in the lowest position of the first lifting groove 401. The lifting frame 404 enables the rotating rod 502 to drive the fixed shaft 503 to be in the lowest position through the lifting block 501. At the same time, the lifting frame 404 enables the lifting block 501 to drive the lifting block 604 to be in the lowest position through the limiting block 601. The bottom of the lifting block 604 is in the lowest position of the second lifting groove 602. At this time, the rotating rod 502 drives the control rod 608 to be in the lowest position of the control groove 606 through the rotating plate 607. Through the control groove 606, the control rod 608 drives the rotating plate 607 to be in a vertically upward state. The rotating plate 607 enables the fixed shaft 503 to drive the scraping plate 504 to contact the inner wall of the observation chamber 1 through the rotating rod 502. The fixed shaft 503 enables the cleaning strip 505 to face inward. The first spring 610 is in a relaxed and contracted state. The first spring 610 enables the magnetic block 611 to be in the highest position of the second lifting groove 602. The second spring 704 is in a relaxed and extended state. The second spring 704 enables the support plate 705 to be in a horizontal state. The support plate 705 enables the electric contact rod 706 to be in a vertically downward state.
[0049] During operation, open the cover plate 2. At this time, place the experimental mouse for observing the treatment of inflammatory bowel disease with mesenchymal stem cells on the support plate 705, and then close the cover plate 2 to observe the experimental mouse. When the experimental mouse crawls normally on the support plate 705, the amplitude of its movement is small at this time, so that the shaking amplitude and speed of the support plate 705 are in a small state. If the experimental mouse shows abnormal restlessness, the swinging amplitude and speed of the support plate 705 will both increase. For example, after the support plate 705 tilts to the right, the support plate 705 compresses the second spring 704 on the right side and stretches the second spring 704 on the left side under the support of the support rod 702. At this time, after the support plate 705 tilts, it drives the lower end of the electric contact rod 706 to tilt to the left. The bottom of the electric contact rod 706 slides rapidly inside the detection groove 707. The rapid sliding on the detection groove 707 can make the electric contact rod 706 energized, thus realizing the rapid detection of the state of the experimental mouse, and being able to judge its restlessness situation in time according to the movement amplitude of the experimental mouse. The sensitivity of the device is improved through universal connection, preventing the problem of jamming during device detection.
[0050] At this time, the circuit is powered on. Since the electric contact rod 706 is electrically connected to the electro-hydraulic rod 403, the electro-hydraulic rod 403 is powered on. After the electro-hydraulic rod 403 is powered on, it drives the lifting frame 404 fixed on its top output end to move upward. The lower end of the lifting frame 404 moves upward inside the first lifting groove 401. The lifting frame 404 moves upward stably under the action of the first stabilizing rod 402, preventing the lifting frame 404 from shaking when moving upward, which may cause the device to be unable to clean effectively. Thus, the effectiveness of the device in cleaning the inner wall of the observation chamber 1 is ensured, and at the same time, the stability of the device during operation is improved. At the same time, when the lifting frame 404 moves upward, the lifting frame 404 drives the rotating rod 502 to move upward through the lifting block 501. The rotating rod 502 drives the fixed shaft 503 to move upward. The rotating rod 502 also drives the control rod 608 to move upward inside the control groove 606 through the rotating plate 607. Under the action of the shape of the control groove 606, after the control rod 608 moves to one side, the rotating rod 502 continues to move upward, causing the positions of the rotating rod 502 and the control rod 608 to be swapped. At this time, the rotating rod 502 will rotate when swapping positions with the control rod 608. The rotating rod 502 drives the fixed shaft 503 to rotate. The fixed shaft 503 drives the scraper 504 to rotate to the inside, and the fixed shaft 503 drives the cleaning strip 505 to rotate to the outside and contact the inner wall of the observation chamber 1. During the continuous upward movement of the lifting frame 404, the lifting frame 404 drives the protective plate 406 to move upward from inside the first recovery groove 405. The rising protective plate 406 can block the experimental mice, preventing the experimental mice from scratching the inner wall of the observation chamber 1 when they are restless. Thus, the problem of scratches on the observation chamber 1 affecting subsequent use can be reduced, the observation efficiency of the device can be improved, and the observation of the experimental mice can be prevented from being affected by scratches.
[0051] The lifting frame 404 continues to move upward. The lifting frame 404 drives the lifting block 501 to move upward. When the lifting block 501 drives the limit block 601 to slide to the highest position inside the limit groove 605, at this time, the bottom of the lifting frame 404 abuts against the bottom of the lifting block 604. The lifting frame 404 pushes the lifting block 604 to move upward. The bottom of the lifting block 604 moves upward inside the second lifting groove 602. The whole lifting block 604 moves upward. At this time, the fixed shaft 503 moves upward synchronously. The fixed shaft 503 drives the cleaning strip 505 to clean the inner wall of the observation chamber 1, thereby cleaning the dust on the inner wall of the observation chamber 1, preventing the dust from affecting the use of the observation chamber 1 and the observation of the experimental mice, and thus ensuring the effectiveness of the observation of the experimental mice. When the lifting block 604 moves to the highest position, at this time, because the bottom of the lifting block 604 is made of a magnetically conductive material, the bottom of the magnetic block 611 is magnetically attracted to the bottom of the lifting block 604.
[0052] When the restlessness of the experimental mouse stops, the detection control component 7 resumes its initial state at this time. After the electro-hydraulic rod 403 is powered off, it contracts. The contraction of the electro-hydraulic rod 403 drives the lifting frame 404 to move downward. The lifting frame 404 drives the protection plate 406 to be retracted into the first recovery groove 405. The lifting frame 404 drives the rotating rod 502 to move downward through the lifting block 501. The rotating rod 502 drives the fixed shaft 503 to move downward. At this time, under the action of the first spring 610 pulling the magnetic block 611, the lifting block 604 is pulled. The rotating rod 502 causes the rotating plate 607 to drive the control rod 608 to move downward inside the control groove 606. The control rod 608 offsets outward under the action of the shape of the control groove 606. The rotating rod 502 continues to move downward. The rotating rod 502 rotates under the action of the offset of the control rod 608. At this time, after the rotating rod 502 rotates, it drives the fixed shaft 503 to rotate. The fixed shaft 503 drives the scraping plate 504 to rotate and contact the inner wall of the observation chamber 1. The fixed shaft 503 drives the cleaning strip 505 to rotate towards the inside. Under the action of the continuous downward movement of the rotating rod 502, the scraping plate 504 is driven by the fixed shaft 503 to clean the dust on the inner wall of the observation chamber 1, solving the problem that the upper end of the inner wall of the observation chamber 1 cannot be cleaned, preventing the influence of dust and making it impossible to clearly see the inner wall of the observation chamber 1. At the same time, after the dust is cleaned downward, it can be collected. At the same time, the water vapor on the inner wall of the observation chamber 1 can also be scraped off to prevent the problem that the water vapor makes the inner wall of the observation chamber 1 blurred. When the lifting block 604 moves to the lowest position, at this time, the lifting block 604 drives the magnetic block 611 to contact the abutting block 609. Under the abutting action of the abutting block 609, the magnetic attraction relationship between the lifting block 604 and the magnetic block 611 is released.
[0053] It should be noted that in this article, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the term "comprising", "including" or any other variant thereof is intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements not only includes those elements, but also includes other elements not expressly listed, or also includes elements inherent to such process, method, article or device. Without further limitation, an element defined by the statement "including a..." does not exclude the existence of additional identical elements in the process, method, article or device including the said element.
[0054] Although the embodiments of the present invention have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principle and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. Observation chamber for treating inflammatory bowel disease mouse model with mesenchymal stem cells, including an observation chamber (1), characterized in that: A cover plate (2) is hinged to the top of the observation chamber (1). A fixed platform (3) is fixedly connected inside the observation chamber (1). A lifting and protecting component (4) is arranged inside the observation chamber (1). A cleaning and scraping component (5) for cleaning the inner wall of the observation chamber (1) is arranged at the top of the lifting and protecting component (4). Rotating and switching components (6) for controlling the rotation of the cleaning and scraping component (5) are arranged on both sides of the cleaning and scraping component (5). A detection and control component (7) for controlling the lifting of the lifting and protecting component (4) is arranged inside the fixed platform (3). The lifting and protecting component (4) includes a first lifting groove (401), a first stabilizing rod (402), an electro-hydraulic rod (403), a lifting frame (404), a first recovery groove (405) and a protection plate (406). The first lifting groove (401) is opened on the inner wall of the observation chamber (1). The first stabilizing rod (402) is fixedly connected inside the first lifting groove (401). The bottom of the electro-hydraulic rod (403) is fixedly connected inside the observation chamber (1). The output end of the top of the electro-hydraulic rod (403) is fixedly connected to the lower surface of the lifting frame (404). The bottom of the lifting frame (404) is movably connected inside the first lifting groove (401). The bottom of the lifting frame (404) is movably connected to the outer wall of the first stabilizing rod (402). The first recovery groove (405) is opened on the fixed platform (3). The upper end of the protection plate (406) is fixedly connected to the inner side of the lifting frame (404). The protection plate (406) is movably connected inside the first recovery groove (405). The cleaning and scraping component (5) includes a lifting block (501), a rotating rod (502), a fixed shaft (503), a scraping plate (504) and a cleaning strip (505). The lifting block (501) is fixedly connected to the upper surface of the lifting frame (404). The rotating rod (502) is rotatably connected to the middle of the lifting block (501). The inner end of the rotating rod (502) is fixedly connected to the outer end of the fixed shaft (503). A scraping plate (504) for scraping the moisture on the inner wall of the observation chamber (1) is fixedly connected to the outside of the fixed shaft (503). A cleaning strip (505) for cleaning the dust on the inner wall of the observation chamber (1) is fixedly connected to the inside of the fixed shaft (503). The rotation switching assembly (6) includes a limit block (601), a second lifting groove (602), a second stabilizing rod (603), a lifting block (604), and a limit groove (605). The limit block (601) is fixedly connected to the outside of the lifting block (501). The second lifting groove (602) is formed in the inner wall of the observation chamber (1). The second stabilizing rod (603) is fixedly connected inside the second lifting groove (602). The lifting block (604) is movably connected to the outside of the limit block (601) through the limit groove (605). The lower outer side of the lifting block (604) is movably connected to the outer wall of the second stabilizing rod (603). The limit groove (605) is formed in the inner surface of the lifting block (604). The rotation switching assembly (6) further includes a resisting block (609), a first spring (610), and a magnetic block (611). The resisting block (609) is fixedly connected to the bottom of the second lifting groove (602). The top of the first spring (610) is fixedly connected to the top of the second lifting groove (602). The bottom of the first spring (610) is fixedly connected to the upper surface of the magnetic block (611). The magnetic block (611) is movably connected to the outer wall of the second stabilizing rod (603). The rotation switching assembly (6) further includes a control groove (606), a rotating plate (607), and a control rod (608). The control groove (606) is formed through the lifting block (604). One end of the rotating plate (607) is fixedly connected to the outer end of the rotating rod (502). The other end of the rotating plate (607) is fixedly connected to the inner end of the control rod (608). The outer end of the control rod (608) is movably connected inside the control groove (606).
2. The mesenchymal stem cell treatment inflammatory bowel disease mouse model observation chamber according to claim 1, characterized in that: The detection and control assembly (7) includes a fixing frame (701), a support rod (702), a second recovery groove (703), a second spring (704), a support plate (705), an electric contact rod (706), and a detection groove (707). The fixing frame (701) is fixedly connected inside the observation chamber (1). The lower surface of the middle part of the fixing frame (701) is fixedly connected to the top of the support rod (702). The second recovery groove (703) is formed in the upper surface of the fixed platform (3). The bottom of the second spring (704) is fixedly connected inside the second recovery groove (703). The top of the second spring (704) is fixedly connected to the lower surface of the support plate (705). The electric contact rod (706) is fixedly connected to the bottom of the support plate (705). The detection groove (707) is formed in the fixed platform (3). The bottom of the electric contact rod (706) abuts against the detection groove (707).
3. The mesenchymal stem cell therapy inflammatory bowel disease mouse model observation chamber according to claim 1, wherein: The lower end of the lifting block (604) is made of a magnetically conductive material. The shape of the control groove (606) is an inclined "V" shape.
4. The mesenchymal stem cell treatment inflammatory bowel disease mouse model observation chamber according to claim 2, characterized in that: The electric contact rod (706) is electrically connected to the electro-hydraulic rod (403). The bottom of the electric contact rod (706) is provided with a telescopic structure. The detection groove (707) is electrically connected to the power supply for equipment use.
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