Excimer laser ablation catheter

Abstract

The application relates to a kind of excimer laser ablation catheters, it relates to the field of optical fiber intervention catheter, the excimer laser ablation catheter includes laser joint, optical fiber catheter, branch connector, intervention catheter and excimer laser fiber, the laser joint, optical fiber catheter, branch connector and intervention catheter are sequentially connected, the excimer laser fiber is extended to the head end of the intervention catheter by the laser joint through the optical fiber catheter and branch connector, the inside of the intervention catheter is provided with lumen tube, one end of the lumen tube is communicated with the branch connector, and the other end is opened in the head end of the intervention catheter, the lumen tube is made of polytetrafluoroethylene material, the head end outside of the lumen tube is crimped with connecting ring, the head end of the excimer laser fiber is connected and sealedly connected with the connecting ring and the wall portion of the intervention catheter, can reduce the adhesion of foreign matter in lumen tube, facilitate the cleaning of lumen tube.

Description

Technical Field

[0001] This application relates to the field of fiber optic interventional catheters, and in particular to an excimer laser ablation catheter. Background Technology

[0002] Excimer lasers are lasers generated by stimulated dimers. They are typically produced by an electron beam exciting a mixture of inert and halogen gases to form dimer molecules. These dimer molecules then transition to their ground state, producing the excimer laser light. When excimer lasers act on biological tissues, they produce a photochemical reaction, not a thermal effect. This means that when the laser irradiates tissue, it causes the bonds between tissue molecules to break, separating the tissue into volatile fragments that dissipate without affecting surrounding tissues. Excimer lasers are increasingly used in corneal refractive surgery, cardiovascular disease treatment, and skin disease treatment.

[0003] When using excimer laser to treat cardiovascular diseases, an excimer laser ablation catheter is typically inserted through the skin into a blood vessel, with its tip inserted to the lesion site requiring treatment. The excimer laser emitted by the laser is guided through the catheter to irradiate the lesion site in the heart or blood vessel, performing ablation therapy. An inner lumen is located inside the excimer laser ablation catheter, through which medications or contrast agents can be injected into the heart or blood vessels, improving the treatment and monitoring effects at the lesion site.

[0004] Existing excimer laser ablation catheters typically have an inner lumen made of materials such as polyvinyl chloride (PVC). When external substances enter the inner lumen, they easily adhere to its walls. Given the small inner diameter of the lumen, cleaning is difficult. Furthermore, these adhered substances can enter the bloodstream during treatment, posing a significant health risk. Summary of the Invention

[0005] To reduce the adhesion of foreign objects inside the inner lumen and facilitate the cleaning of the inner lumen, this application provides an excimer laser ablation catheter.

[0006] The excimer laser ablation catheter provided in this application adopts the following technical solution:

[0007] An excimer laser ablation catheter includes a laser connector, an optical fiber conduit, a branch connector, an interventional catheter, and an excimer laser fiber. The laser connector, optical fiber conduit, branch connector, and interventional catheter are connected in sequence. The excimer laser fiber extends from the laser connector through the optical fiber conduit and the branch connector to the tip of the interventional catheter. The interventional catheter has an inner lumen tube inside. One end of the inner lumen tube is connected to the branch connector, and the other end opens at the tip of the interventional catheter. The inner lumen tube is made of polytetrafluoroethylene (PTFE). A connecting ring is crimped to the outer side of the tip of the inner lumen tube. The tip of the excimer laser fiber is sealed to the connecting ring and the wall of the interventional catheter.

[0008] By adopting the above technical solution, the inner tube made of polytetrafluoroethylene (PTFE) material can reduce the adhesion of foreign matter to the tube wall, facilitating the cleaning of foreign matter inside the inner tube. The connecting ring at the head end of the inner tube allows the end of the excimer laser fiber to be reliably connected between the inner tube and the wall of the interventional catheter, forming a seal at the head end of the interventional catheter and overcoming the defect that PTFE material is not easy to adhere to and cannot guarantee a sealing end. The connection ring pressed against the outside of the head end of the inner tube creates an interference fit between the inner tube and the connecting ring, and the elasticity of the PTFE material forms a reliable seal between the inner tube and the connecting ring.

[0009] In one specific implementation, the inner lumen is located in the middle of the interventional catheter, and multiple excimer laser fibers are wrapped around the periphery of the inner lumen.

[0010] By adopting the above technical solution, the inner lumen tube located in the middle of the interventional catheter can accurately deliver the drug solution and improve the heat dissipation performance of the surrounding excimer laser fiber; the arrangement of the excimer laser fiber surrounding the inner lumen tube can improve the uniformity of the excimer laser emitted from the tip of the interventional catheter and improve the laser ablation effect.

[0011] In one specific implementation, multiple excimer laser fibers are arranged in layers around the periphery of the inner cavity tube, forming multiple concentric circles.

[0012] By adopting the above technical solution and utilizing multiple concentrically arranged excimer laser fibers, the distribution range of the excimer laser emitted through the tip of the interventional catheter can be optimized, resulting in a more uniform laser ablation effect.

[0013] In one specific implementation, the connecting ring is made of a metal material and is fixed to the head end of the inner tube by a spinning process.

[0014] By employing the above technical solution, utilizing the ductility and compressibility of metallic materials, the diameter of the connecting ring can be uniformly reduced through a spinning process. This creates a balanced compression around the periphery of the inner tube wall, allowing it to reliably nest onto the inner tube wall, forming a reliable connection and seal between the connecting ring and the inner tube. The metallic material also allows for better adhesion of adhesives, forming an adhesive seal with the excimer laser fiber.

[0015] In one specific implementation, the outer wall of the connecting ring is flush with the outer wall of the adjacent inner tube.

[0016] By adopting the above technical solution, the flatness of the inner side of the excimer laser fiber can be improved by making the outer wall of the connecting ring flush with the outer wall of the adjacent inner cavity tube, thus preventing the excimer laser fiber from bending due to the pressure of the edge of the connecting ring end.

[0017] In one specific implementation, the tip of the interventional catheter is further provided with a radiopaque ring, which is spliced ​​to the tip of the sheath of the outer layer of the interventional catheter and located outside the excimer laser fiber.

[0018] By adopting the above technical solution, the imaging ring set at the tip of the interventional catheter can be clearly imaged in X-ray images, showing the position of the tip of the interventional catheter in the blood vessel or heart, which facilitates the accurate delivery of the tip of the interventional catheter to the lesion site for effective laser ablation treatment.

[0019] In one specific implementation, the developing ring is made of a tantalum alloy or a platinum-iridium alloy.

[0020] By adopting the above technical solutions, the high density of tantalum, platinum, and iridium can impede the passage of X-rays, thereby enabling the formation of clearer images in X-ray imaging. The extremely high corrosion resistance of tantalum, platinum, and iridium can prevent corrosion of the imaging ring during storage and use, and reduce the stimulation of human tissues by the excimer laser ablation catheter.

[0021] In one specific implementation, the tip of the interventional catheter protrudes outward, and the tip of the excimer laser fiber is located on the protruding surface.

[0022] By adopting the above technical solution, the excimer laser emitted through the excimer laser fiber can be diffused laterally by utilizing the outwardly protruding end face of the interventional catheter, thereby expanding the irradiation range of the excimer laser and improving the ablation effect on body tissues.

[0023] In one specific implementation, the end face of the interventional catheter tip includes a plane located in the middle of the end face and an outwardly convex curved surface located on the outer periphery, the tip of the inner lumen tube is located on the plane, and the tip of the excimer laser fiber is located on the outwardly convex curved surface.

[0024] By adopting the above technical solution, the stability of the flow direction of the drug solution input through the inner lumen tube can be improved by using the setting of the head end of the inner lumen tube on a plane, and the stimulation of the body by the edge of the end of the inner lumen tube can be reduced; the setting of the head end of the excimer laser fiber on the convex curved surface can ensure the diffusion of the excimer laser emitted through the excimer laser fiber.

[0025] In one specific implementation, the end face of the interventional catheter tip is an outwardly convex spherical surface.

[0026] By adopting the above technical solution, the end face of the interventional catheter tip is integrally formed into an outwardly convex curved surface, which facilitates the processing and shaping of the end face of the interventional catheter tip. The spherical curved surface can form a more uniform extended irradiation range for the excimer laser.

[0027] In summary, this application includes at least one of the following beneficial technical effects:

[0028] 1. The inner tube made of polytetrafluoroethylene (PTFE) material can improve the chemical stability, high lubricity and non-stickiness, and anti-aging ability of the inner tube, prevent foreign objects from adhering to the inner tube wall, improve the cleaning effect of the inner tube lumen, reduce the irritation of the inner tube material to the body tissue, and ensure the service life of the inner tube.

[0029] 2. By crimping the connecting ring to the inner lumen tube, an interference fit connection is formed between the connecting ring and the inner lumen tube. The elasticity of the polytetrafluoroethylene material is used to form a reliable seal between the inner lumen tube and the connecting ring, preventing body fluid from seeping into the interventional catheter outside the inner lumen tube, causing contamination and corrosion of the excimer laser ablation catheter.

[0030] 3. By utilizing the connection between the excimer laser fiber and the connecting ring, a sealed connection can be formed between the excimer laser fiber tip and the inner lumen tube. This overcomes the defect that polytetrafluoroethylene (PTFE) material cannot form a sealed connection with the excimer laser fiber due to its insolubility in any solvent and its inability to adhere to any substance. The connecting ring ensures a reliable seal at the tip of the interventional catheter. Attached Figure Description

[0031] Figure 1 This is a schematic diagram of one embodiment of the excimer laser ablation catheter of this application.

[0032] Figure 2 This is a schematic cross-sectional view of the tip portion of the excimer laser ablation catheter in one embodiment of the present application.

[0033] Figure 3 This is a schematic diagram of the excimer laser fiber arrangement in another embodiment of the excimer laser ablation catheter of this application.

[0034] Figure 4 This is a schematic diagram of the state of the connecting ring before it is spun in one embodiment of the excimer laser ablation catheter of this application.

[0035] Figure 5 This is a schematic diagram of the state of the connecting ring after it has been spun in one embodiment of the excimer laser ablation catheter of this application.

[0036] Figure 6 This is a longitudinal cross-sectional view of the tip portion of the excimer laser ablation catheter in one embodiment of the present application.

[0037] Figure 7 This is a longitudinal cross-sectional view of the tip portion of the interventional catheter in another embodiment of the excimer laser ablation catheter of this application.

[0038] Explanation of reference numerals in the attached diagram: 1. Laser connector; 2. Fiber optic conduit; 3. Branch connector; 4. Interventional catheter; 41. Inner lumen tube; 42. Connecting ring; 43. Imaging ring; 44. Sheath tube; 5. Excimer laser fiber. Detailed Implementation

[0039] The specific embodiments of this application will now be described in detail with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are for illustration and explanation only and are not intended to limit this application.

[0040] In the description of this application, it should be noted that, unless otherwise expressly specified and limited, the terms "set" and "connection" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two elements or the interaction between two elements. Those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.

[0041] One embodiment of the excimer laser ablation catheter of this application, such as Figure 1 and Figure 2 As shown, it includes a laser connector 1, an optical fiber conduit 2, a branch connector 3, an interventional catheter 4, and an excimer laser fiber 5. The laser connector 1, optical fiber conduit 2, branch connector 3, and interventional catheter 4 are connected to each other in sequence. The excimer laser fiber 5 extends from the laser connector 1, passes through the optical fiber conduit 2 and branch connector 3, and enters the interventional catheter 4, connecting to the end face of the tip of the interventional catheter 4.

[0042] The interventional catheter 4 is inserted into a blood vessel to guide the excimer laser fiber 5 to the lesion site in the heart or blood vessels. The interventional catheter 4 is typically surrounded by a medical-grade rubber sheath 44, which protects the internal excimer laser fiber 5 while maintaining flexibility to allow passage through long and tortuous blood vessels. Depending on the location of the lesion, interventional catheters 4 of various diameters can be used.

[0043] The interventional catheter 4 has an internal lumen 41 made of polytetrafluoroethylene (PTFE) for injecting drugs, saline, or contrast agents into lesions in the heart or blood vessels when necessary. One end of the lumen 41 is connected to the branch connector 3, and the other end opens onto the tip of the interventional catheter 4. A connecting ring 42 is press-fitted to the outer side of the tip of the lumen 41. The connecting ring 42 can be made of various metal materials, typically corrosion-resistant and highly ductile, such as stainless steel or titanium alloy. The connecting ring 42 is fitted onto the tip of the lumen 41, and pressure is applied to its outer side, causing it to deform and contract. The contracted connecting ring 42 compresses the lumen 41, causing the wall material of the lumen 41 to flow and deform, tightly nesting the connecting ring 42 onto the lumen 41. The elasticity of the PTFE material forms a strong connection and reliable seal between the lumen 41 and the connecting ring 42.

[0044] Of course, plastics such as PVC, PE, and PP can also be used to form a connecting ring 42 on the inner tube 41 by compression molding or calendering. In this way, through the molding and curing of the connecting ring 42 under pressure and the deformation and shrinkage of the inner tube 41 under pressure, an interference fit connection between the inner tube 41 and the connecting ring 42 can be formed after the pressure is removed, and a reliable seal can be formed between the two.

[0045] The excimer laser fiber 5 passes through the outside of the inner lumen tube 41 and the inside of the sheath tube 44, transmitting the excimer laser to the tip of the interventional catheter 4. The laser beam exits from the end face of the tip, irradiating the diseased tissue within the heart and blood vessels for laser ablation. The end of the excimer laser fiber 5 can be bonded to the end structure of the connecting ring 42 and the sheath tube 44 using medical adhesive. After the medical adhesive cures, a connection is formed between the excimer laser fiber 5, the metal ring 42, and the inner lumen tube 41, creating a sealed connection between the different structures at the tip of the interventional catheter 4. Specifically, suitable adhesives, sealants, or coatings such as medical epoxy resin can be applied around the excimer laser fiber 5 to form a connection and seal between the excimer laser fiber 5, the connecting ring 42, and the inner lumen tube 41.

[0046] The branch connector 3 connects the interventional catheter 4 and the fiber optic catheter 2, and includes an integrally connected connecting part 31 and a branch interface 32. The branch interface 32 is connected to the inner lumen tube 41 through a connecting tube disposed inside the connecting part 31. The inner lumen tube 41 and the connecting part 31 can be connected by an interference fit, or the inner lumen tube 41 can extend all the way to the opening of the branch interface 32. On the one hand, the branch connector 3 is a rigid structure that does not require bending, which makes it easier to form a reliable interference fit with the inner lumen tube 41 and prevents leakage between the inner lumen tube 41 and the branch connector 3. On the other hand, during use, the branch connector 3 is located outside the human body and is not immersed in liquid, so it is less likely to cause liquid leakage and contamination.

[0047] An elastic sleeve can also be provided between the branch connector 3 and the interventional catheter 4. The elastic sleeve can protect the connection end between the interventional catheter 4 and the branch connector 3 and prevent excessive bending at the connection point of the interventional catheter 4.

[0048] The excimer laser fiber 5 enters one end of the connecting part 31 from the interventional catheter 4 and exits from the other end of the connecting part 31 into the fiber optic catheter 2.

[0049] The fiber optic conduit 2 connects the laser connector 1 and the branch connector 3 to accommodate and protect the excimer laser fiber 5. During use, the branch connector 3 is usually placed near the patient for easy access by medical staff, while the laser connector 1 is usually inserted into the laser. A certain distance needs to be maintained between the two. The fiber optic conduit 2 facilitates the excimer laser fiber 5 to cross a relatively long distance and enter the interventional catheter 4.

[0050] Laser connector 1 is used to connect to a laser or other connectors connected to a laser, thereby guiding the excimer laser generated by the laser into the excimer laser fiber 5. Laser connector 1 can be various standard commercially available connectors, or it can be a non-standard connector designed according to the matching interface shape and existing connector principles.

[0051] One end of the laser connector 1 is provided with an interface for transmitting excimer laser. The excimer laser fiber 5 typically enters the interior of the laser connector 1 and connects to the laser interface. A rubber sleeve is provided at the connection between the laser connector 1 and the fiber optic conduit 2. The rubber sleeve is fitted over the fiber optic conduit 2 to prevent excessive bending at the connection point of the fiber optic conduit 2.

[0052] To ensure the light transmission performance of the excimer laser fiber 5 and improve its laser transmission efficiency, the end face of the interventional catheter 4 is typically polished during the fabrication of the excimer laser ablation catheter. Impurities formed during this polishing process inevitably enter the lumen of the inner tube 41. During use, the interventional catheter 4 is inserted into a blood vessel, and blood components can easily enter the lumen of the inner tube 41. All of these factors can lead to foreign bodies adhering to the inner wall of the inner tube 41. Once these foreign bodies enter the blood vessels, they pose a serious threat to human health.

[0053] The inner lumen of a typical excimer laser ablation catheter is made of common medical plastics, such as polyvinyl chloride (PVC) and PE. Foreign objects entering the lumen can easily deposit and adhere to the inner wall of the lumen, requiring cleaning. Due to the small diameter of the inner lumen, cleaning can only be done by flushing with water or high-pressure air, which is cumbersome and ineffective.

[0054] PTFE is a novel high-molecular plastic that is insoluble in any solvent, has extremely low surface tension, and does not adhere to any substance. It possesses advantages such as high chemical stability, strong corrosion resistance, and high lubricity without sticking. When used to fabricate the inner lumen tube 41, it effectively prevents foreign matter from adhering to the tube wall, thus facilitating the cleaning and removal of foreign matter entering the lumen tube 41. However, due to PTFE's insolubility and non-adhesion properties, using PTFE to fabricate the inner lumen tube 41 makes it difficult to connect and seal the tip of the inner lumen tube 41 with the excimer laser fiber 5 or other structures at the end of the interventional catheter 4. During use, cleaning, or sterilization, external hydraulic pressure can easily enter the interior of the interventional catheter 4 through gaps in the inner lumen tube 41, causing contamination and severely hindering the application of PTFE in various interventional catheters. The problem of foreign matter adhesion in the inner lumen tube 41 and its difficulty in cleaning have become intractable issues in this field.

[0055] This application achieves a reliable connection between the inner tube 41 and the connecting ring 42 by pressing a connecting ring 42 onto the tip of the PTFE inner tube 41. The deformation of the connecting ring 42 under pressure and the deformation of the tip of the inner tube 41 under pressure are used to form a reliable connection between the inner tube 41 and the connecting ring 42. A reliable seal is formed between the inner tube 41 and the connecting ring 42 through an interference fit. The connecting ring 42 is then connected to the excimer laser fiber 5 to form a reliable seal between the connecting ring 42 and the excimer laser fiber 5. This effectively solves the connection and sealing problem between the PTFE inner tube 41 and the excimer laser fiber 5, ensuring the sealing performance of the tip of the interventional catheter 4. Thus, the application of the PTFE inner tube 41 to the excimer laser ablation catheter successfully solves the technical problem of foreign matter adhering to and being difficult to clean in the inner tube 41.

[0056] In a preferred embodiment of the excimer laser ablation catheter of this application, such as Figure 2 and Figure 3 As shown, inside the interventional catheter 4, the inner lumen tube 41 is located in the middle of the interventional catheter 4, that is, near the central axis of the interventional catheter 4. Multiple excimer laser fibers 5 are disposed inside the interventional catheter 4, and the multiple excimer laser fibers 5 are disposed in the peripheral area of ​​the interventional catheter 4, arranged around the periphery of the inner lumen tube 41.

[0057] As one specific embodiment of the excimer laser ablation catheter of this application, such as Figure 3 As shown, inside the interventional catheter 4, multiple excimer laser fibers 5 are arranged in several layers around the periphery of the inner lumen tube 41, forming 2-5 concentric circles surrounding the inner lumen tube 41, thus forming a circular array of excimer laser fibers 5.

[0058] In some embodiments of the excimer laser ablation catheter of this application, the connecting ring 42 is made of a metallic material, typically stainless steel, titanium, titanium alloys, cobalt-based alloys, etc. During the manufacturing process, such as... Figure 4 As shown, a connecting ring 42 made of metal is fitted onto the head end of the inner tube 41. The outer circumference of the connecting ring 42 is spun using a spinning device, causing the connecting ring 42 to gradually shrink. The inner wall of the connecting ring 42 compresses the inner tube 41, causing the PTFE material of the inner tube 41 wall to deform and flow, resulting in thinning of the tube wall at the end of the inner tube 41. Simultaneously, the connecting ring 42 also stretches and thins. In this way, the connecting ring 42 is nested into the end of the inner tube 41 through a spinning process, forming a shape as shown... Figure 5 The connection between the connecting ring 42 and the inner tube 41 is shown. The connecting ring 42, due to compression and contraction, covers the outer periphery of the inner tube 41. The inner tube 41, due to its own elasticity, tightly abuts against the inner wall of the connecting ring 42, forming an interference fit between the inner tube 41 and the connecting ring 42. This fixes the connecting ring 42 to the head end of the inner tube 41 and forms a reliable seal between the two.

[0059] As one specific embodiment of the excimer laser ablation catheter of this application, such as Figure 5 As shown, the diameter of the connecting ring 42 gradually decreases due to spinning deformation, and the inner wall of the connecting ring 42 compresses the inner tube. Under the compression of the connecting ring 42, the outer diameter of the inner tube 41 located inside the connecting ring 42 decreases, and at the same time, the reduction in the diameter of the connecting ring 42 makes the outer wall of the connecting ring 42 flush with the outer wall of the adjacent inner tube 41. The way the connecting ring 42 is fixed to the inner tube 41 by the spinning process ensures that the inner diameter of the inner tube 41 does not decrease significantly.

[0060] In some embodiments of the excimer laser ablation catheter of this application, such as Figure 6 and Figure 7 As shown, a contrast-enhancing ring 43 is provided at the tip of the interventional catheter 4. The contrast-enhancing ring 43 can be made of various materials that are visible on X-ray images, allowing the image of the contrast-enhancing ring 43 to be observed using X-ray imaging equipment. This facilitates the observation of the position of the contrast-enhancing ring 43 within the blood vessels or heart, which in turn indicates the position of the tip of the interventional catheter 4 within the blood vessels or heart. This helps the excimer laser accurately irradiate the lesion tissue in the blood vessels or heart, performing laser ablation of the lesion tissue, and accurately delivering necessary drugs or saline to the lesion site, thus improving the treatment effect.

[0061] A sheath 44 is provided outside the interventional catheter 4, covering the outer layer of the excimer laser fiber 5 and forming a protective layer for the excimer laser fiber 5. A contrast ring 43 is sleeved on the tip of the interventional catheter 4, replacing the sheath 44 which covers the outer periphery of the excimer laser fiber 5. The contrast ring 43 is located on one side of the end face of the interventional catheter 4, forming part of the end face of the interventional catheter 4, and the other side is spliced ​​with the sheath 44. Specifically, it can be connected by various possible connection methods such as adhesive bonding.

[0062] Compared to the traditional method of attaching the contrast ring 43 to the outside of the sheath 44 or placing the sheath 44 over the contrast ring 43, the method of splicing the contrast ring 43 with the sheath 44 can simultaneously ensure that the contrast ring 43 is flush with both the inner and outer walls of the sheath 44. This not only prevents the excimer laser fiber 5 from being bent under pressure, but also ensures the smoothness of the periphery of the interventional catheter 4, which is conducive to the unimpeded passage of the interventional catheter 4 through small blood vessels.

[0063] In a preferred embodiment of the excimer laser ablation catheter of this application, the imaging ring 43 is made of tantalum alloy or platinum-iridium alloy. Tantalum is a transition metal with extremely high corrosion resistance, high density, and good toughness, which can effectively block the passage of X-rays and thus be visualized in X-ray images. Similarly, platinum-iridium alloys are platinum-based binary alloys containing iridium, including alloys such as Ptlr10, Ptlr17.5, Ptlr25, and Ptlr30, which have high density, high melting point, and high corrosion resistance, and can effectively block the passage of X-rays. The imaging ring 43 made of tantalum or platinum-iridium alloy can be clearly visualized in X-ray images with a thinner ring thickness, thus enabling its application in excimer laser ablation catheters with smaller diameters.

[0064] In some embodiments of the excimer laser ablation catheter of this application, such as Figure 6 and Figure 7As shown, the end face of the interventional catheter 4 is formed into an outwardly convex structure. Typically, during the fabrication of excimer laser ablation catheters, the end face of the interventional catheter 4 needs to be ground and polished to improve the light transmittance of the excimer laser fiber 5's output end, ensuring high-efficiency transmission of the excimer laser within the fiber. The convex structure of the end face of the interventional catheter 4 can usually be achieved by controlling the amount of grinding at different parts of its end face. Specifically, by increasing the amount of grinding removal on the outer periphery of the end face of the interventional catheter 4 and decreasing the amount of grinding removal on the middle part of the end face of the interventional catheter 4, an outwardly convex end face is formed. This outwardly convex end face usually has a rotating surface coaxial with the interventional catheter 4. This rotating surface can be a conical surface, a spherical surface, or an ellipsoidal surface, etc.

[0065] The tip of the excimer laser fiber 5 is connected to the convex surface on the outer periphery of the end face of the interventional catheter 4, so that the end face of the excimer laser fiber 5 forms an inclined surface towards the outer periphery of the interventional catheter 4. When the excimer laser is emitted through the end face of the excimer laser fiber 5, the excimer laser will be deflected towards the outer periphery of the interventional catheter 4, increasing the irradiation range of the excimer laser emitted from the end face of the interventional catheter 4, which is beneficial to improving the efficiency of laser ablation of diseased tissues in blood vessels and the heart.

[0066] In a preferred embodiment of the excimer laser ablation catheter of this application, such as Figure 6 As shown, the outer periphery of the end face of the interventional catheter 4 is machined into an outwardly convex curved surface, while the middle portion of the end face is machined into a plane perpendicular to the central axis of the interventional catheter 4. The tip of the inner lumen 41 opens onto the plane in the middle of the end face, ensuring a straight wall at the outlet of the inner lumen 41. This guarantees a stable flow of medication through the inner lumen 41 and reduces irritation to blood vessels and the heart wall caused by the inner lumen 41 wall. The tip of the excimer laser fiber 5 is connected to the outwardly convex curved surface, ensuring that the excimer laser emitted through the end face of the excimer laser fiber 5 diffuses towards the periphery of the interventional catheter 4.

[0067] In another preferred embodiment of the excimer laser ablation catheter of this application, such as Figure 7 As shown, the end face of the tip of the interventional catheter 4 is integrally machined into an outwardly convex curved surface. This curved surface can be a conical surface with the central axis of the interventional catheter 4 as the axis of rotation, or a spherical surface with its center on the central axis of the interventional catheter 4. Alternatively, the end face of the tip of the interventional catheter 4 can also be machined into an ellipsoidal surface with the central axis of the interventional catheter 4 as the major axis, or a parabolic surface with the central axis of the interventional catheter 4 as the axis of rotation, or other curved surfaces.

[0068] In this embodiment, the end faces of the four ends of the interventional catheter can be formed in a single process, simplifying the manufacturing process. The specific shape of the convex curved surface can be reasonably selected according to the distribution requirements of the excimer laser.

[0069] In the description of this invention, the terms "one embodiment," "specific embodiment," "preferred embodiment," etc., refer to specific features, structures, materials, or characteristics described in connection with that embodiment or example, which are included in at least one embodiment or example of the invention. In this invention, illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0070] The above are all preferred embodiments of this application and are not intended to limit the scope of protection of this application. Therefore, all equivalent changes made in accordance with the structure, shape and principle of this application should be covered within the scope of protection of this application.

Claims

1. An excimer laser ablation catheter, characterized in that: The device includes a laser connector (1), an optical fiber conduit (2), a branch connector (3), an interventional catheter (4), and an excimer laser fiber (5). The laser connector (1), optical fiber conduit (2), branch connector (3), and interventional catheter (4) are connected in sequence. The excimer laser fiber (5) extends from the laser connector (1) through the optical fiber conduit (2) and the branch connector (3) to the head end of the interventional catheter (4). The interventional catheter (4) has an inner lumen tube (41) inside. One end of the inner lumen tube (41) is connected to the branch connector (3), and the other end opens at the head end of the interventional catheter (4). The inner lumen tube (41) is made of polytetrafluoroethylene. A connecting ring (42) is crimped to the outer side of the head end of the inner lumen tube (41). The outer wall of the connecting ring (42) is flush with the outer wall of the adjacent inner lumen tube (41). The head end of the excimer laser fiber (5) is sealed to the connecting ring (42) and the wall of the interventional catheter (4).

2. The excimer laser ablation catheter according to claim 1, characterized in that: The inner lumen tube (41) is located in the middle of the interventional catheter (4), and multiple excimer laser optical fibers (5) are wrapped around the periphery of the inner lumen tube (41).

3. The excimer laser ablation catheter according to claim 2, characterized in that: Multiple excimer laser fibers (5) are arranged in layers around the periphery of the inner cavity tube (41) to form multiple concentric circles.

4. The excimer laser ablation catheter according to claim 1, characterized in that: The connecting ring (42) is made of metal material and is fixed to the head end of the inner tube (41) by a spinning process.

5. The excimer laser ablation catheter according to claim 1, characterized in that: The tip of the interventional catheter (4) is provided with a contrast ring (43), which is spliced ​​to the tip of the sheath tube (44) of the outer layer of the interventional catheter (4) and located outside the excimer laser fiber (5).

6. The excimer laser ablation catheter according to claim 5, characterized in that: The developing ring (43) is made of tantalum alloy or platinum-iridium alloy.

7. The excimer laser ablation catheter according to any one of claims 1-6, characterized in that: The tip of the interventional catheter (4) protrudes outward, and the tip of the excimer laser fiber (5) is located on the protruding surface.

8. The excimer laser ablation catheter according to claim 7, characterized in that: The end face of the interventional catheter (4) includes a plane in the middle of the end face and an outwardly convex curved surface on the outer periphery. The end of the inner lumen tube (41) is located on the plane, and the end of the excimer laser fiber (5) is located on the outwardly convex curved surface.

9. The excimer laser ablation catheter according to claim 7, characterized in that: The tip of the interventional catheter (4) has a spherical end face.

Images