A cleaning solution and its preparation method and cleaning method

Abstract

The present invention relates to a detergent solution, and relates to the field of cleaning technology. The detergent solution comprises the following components by mass ratio: 4% to 7% anionic surfactant; 3% to 5% zwitterionic surfactant; 0.05% to 0.15% Tween-20; 1% to 2% auxiliary agent; and the remainder is water. The preparation method of the detergent solution comprises the following steps: S1: adding auxiliary agents to water and stirring evenly; S2: adding anionic surfactant and Tween-20 to S1 and stirring evenly; S3: adding zwitterionic surfactant to S2 and stirring evenly. The cleaning method of the detergent solution comprises the following steps: 1) placing the gold-dotting machine pipe to be cleaned into the detergent and ultrasonically cleaning it; 2) after the ultrasonic cleaning is completed, installing the cleaned pipe on the gold-dotting machine, performing a second cleaning, and emptying the pipe after the second cleaning. The present invention has the effect of effectively removing color and solution residues from the gold-dotting machine pipe and its components.

Description

Technical Field

[0001] The present invention relates to the technical field of cleaning, and in particular to a cleaning solution, a preparation method thereof, and a cleaning method. Background Art

[0002] At present, in the production process of biological test kits, the gold dotting workshop needs to spray the diluted gold label / latex solution evenly on the marking pad. When performing gold dotting on large and small samples, since the gold label / latex solution is colored, the pipeline that transports the gold label / latex solution is severely stained and easily has solution residue, which is difficult to remove by simple flushing methods. Consider using detergent to clean the pipeline.

[0003] A Chinese patent application with publication number CN111205935A discloses a food-grade dishwashing liquid and a preparation method thereof, which discloses that, in terms of mass percentage, it contains 5% to 30% of a main surfactant and 3% to 20% of a secondary surfactant, wherein the main surfactant is an alkyl glycoside, and the secondary surfactant is one or more of Tween, tea saponin and monoglyceride.

[0004] The above-mentioned existing technical solutions have the following defects: because the inner diameter of the gold-touching machine pipe is small and transparent, brushes and other tools cannot be inserted into the gold-touching machine pipe. The above-mentioned patent application and the existing commercially available cleaners cannot completely remove the color on the pipe wall by immersion. The gold-touching machine pipe is still severely stained and there is solution residue. In addition, the cost of replacing pipe fittings is high. Therefore, the inventors came up with a cleaner specially designed for cleaning the gold-touching machine pipe, and proved the effectiveness of the cleaner through corresponding practice. Summary of the Invention

[0005] In view of the shortcomings of the existing technology, one of the purposes of the present invention is to provide a detergent solution that can effectively remove the color and solution residues in the gold-touching machine pipeline; the second purpose of the present invention is to provide a method for preparing a detergent solution, which can prepare a detergent that has a good removal effect on the residual solvent in the gold-touching machine pipeline; the third purpose of the present invention is to provide a cleaning method for the detergent solution.

[0006] One of the above-mentioned objectives of the present invention is achieved through the following technical solutions:

[0007] A cleaning solution, characterized by comprising the following components in a mass ratio:

[0008] Anionic surfactant 4~7%;

[0009] Zwitterionic surfactant 3%~5%;

[0010] Tween-20 0.05%~0.15%;

[0011] Auxiliary reagents 1~2%;

[0012] Water balance.

[0013] By adopting the above technical solution, the residual color and solvent in the gold-turning machine pipeline can be effectively removed through the effects of anionic surfactants, zwitterionic surfactants and Tween-20, and there is no need to replace the pipeline due to residual solvent in the pipeline, thereby reducing the cost of replacing pipelines and accessories to a certain extent.

[0014] Preferably, the anionic surfactant comprises sodium lauryl sulfate.

[0015] Preferably, the zwitterionic surfactant includes one or more combinations of cocamidopropyl betaine and lauramidopropyl betaine.

[0016] By adopting the above technical solution, cocamidopropyl betaine and lauramidopropyl betaine are both effective in removing residual color and solvent from the pipes of gold-turning machines. Furthermore, cocamidopropyl betaine has a certain thickening and antibacterial effect when combined with sodium lauryl sulfate. Lauramidopropyl betaine also has certain thickening and antibacterial effects when combined with the above-mentioned anionic surfactants. Lauramidopropyl betaine can also impart a pleasant aromatic odor to the cleaning solution.

[0017] Preferably, the auxiliary agent includes butyl laurate.

[0018] By adopting the above technical solution, the auxiliary reagent includes butyl laurate as a defoaming agent. Combined with ultrasound in the subsequent cleaning step, it can reduce foam generation to a certain extent, thereby reducing foam residue in the corners of the gold-turning machine pipes and pipe components. After cleaning with the detergent solution, it is easy to clean and remove the detergent solution residue. At the same time, the combination of butyl laurate and lauric acid amidopropyl betaine can also give the detergent solution a pleasant aroma.

[0019] Preferably, the auxiliary agent includes at least one of carboxymethyl cellulose, hydroxyethyl cellulose, and hydroxypropyl methyl cellulose.

[0020] By adopting the above technical solution, carboxymethyl cellulose, hydroxyethyl cellulose and hydroxypropyl methyl cellulose can all play a role in stabilizing the detergent solution, and can make the detergent solution present a relatively stable and uniform liquid state.

[0021] Preferably, the auxiliary reagents include dimethyl sulfoxide and benzyltrimethylammonium hydroxide.

[0022] By adopting the above technical solution, dimethyl sulfoxide (DMSO) serves as a relatively effective decontamination solvent, effectively removing residual gold label / latex solution and its color from the gold-doping machine's pipes and components. DMSO also acts as a defoaming agent. Benzyltrimethylammonium hydroxide provides a certain alkaline environment, ensuring the stability of DMSO to a certain extent. Furthermore, sodium lauryl sulfate, cocamidopropyl betaine, and lauramidopropyl betaine all exhibit good stability in alkaline environments. Benzyltrimethylammonium hydroxide can also improve the overall stability of the detergent solution to a certain extent.

[0023] Preferably, the auxiliary reagent includes sodium dehydroacetate.

[0024] By adopting the above technical solution, sodium dehydroacetate has a broad-spectrum antibacterial ability, and sodium dehydroacetate is weakly alkaline in aqueous solution, which can also enhance the overall stability of the detergent solution to a certain extent.

[0025] The second object of the present invention is achieved through the following technical solutions:

[0026] A method for preparing the detergent solution comprises the following steps:

[0027] S1: Add auxiliary reagents to water and stir evenly;

[0028] S2: Add anionic surfactant and Tween-20 to S1 and stir evenly;

[0029] S3: Add zwitterionic surfactant to S2 and stir evenly.

[0030] By adopting the above technical solution, auxiliary reagents, namely dimethyl sulfoxide, benzyltrimethylammonium hydroxide, sodium dehydroacetate, carboxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl methylcellulose, and butyl laurate, are first added to water, and then anionic surfactants, Tween-20, and zwitterionic surfactants are added, which can reduce the time required for uniform stirring to a certain extent.

[0031] The third object of the present invention is achieved through the following technical solutions:

[0032] A cleaning method using the detergent solution comprises the following steps:

[0033] 1) Place the gold-dotting machine pipe that needs to be cleaned in the detergent and perform ultrasonic cleaning;

[0034] 2) After the ultrasonic treatment, install the cleaned pipe on the gold-dotting machine for a second cleaning. After the second cleaning, drain the pipe.

[0035] By adopting the above technical solution, when cleaning the gold-dotting machine pipes and their components, they are placed in a detergent solution and ultrasonically treated. Ultrasound not only has a better cleaning effect, but also helps to remove the gold label / latex solution residue adhering to the gold-dotting machine pipes and their components; and the defoaming agent combined with ultrasonic cleaning can reduce the generation of foam to a certain extent, while also ensuring a better cleaning effect.

[0036] Preferably, the second washing comprises, in order: washing with water 10 times, washing with 0.1 mol / L HCl 10 times, washing with 0.1 mol / L NaOH 10 times, and washing with water 10 times.

[0037] By adopting the above technical solution, water washing can be performed first to remove most of the detergent residues on the gold-turning machine pipes and its components to a certain extent, and then acid washing is performed to remove H ﹢ The trend is that the aqueous solution is completely ionized, and the positive ions that can be ionized at this time are only H ﹢ ; Then after alkaline washing, the negative ions ionized are only hydroxide ions; acid washing and water washing can remove the detergent solution still remaining on the gold-touching machine pipes and its components, and to a certain extent avoid the impact on the gold-touching machine pipes and its components during use, that is, avoid the gold-touching machine pipes and its components from affecting the gold label / latex solution when transporting the gold label / latex solution.

[0038] In summary, the present invention includes at least one of the following beneficial technical effects:

[0039] 1. Through the action of anionic surfactants, zwitterionic surfactants and Tween-20, the residual color and solvent in the gold-turning machine pipe can be effectively removed, so there is no need to replace the pipe due to residual solvent in the pipe, which reduces the cost of replacing pipes and accessories to a certain extent;

[0040] 2. When cleaning the gold-dotting machine pipes and their components, place them in a detergent solution and perform ultrasonic cleaning. Ultrasonic cleaning can not only achieve a better cleaning effect, but also help remove the gold label / latex solution residue adhering to the gold-dotting machine pipes and their components. In addition, the defoaming agent combined with ultrasonic cleaning can reduce the generation of foam to a certain extent, while also ensuring a better cleaning effect. DETAILED DESCRIPTION

[0041] Preparation Example 1

[0042] The auxiliary reagents include butyl laurate, carboxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl methyl cellulose, dimethyl sulfoxide, benzyltrimethylammonium hydroxide and sodium dehydroacetate, and the added mass of each component is equal.

[0043] Preparation Example 2-11

[0044] The difference between Preparation Example 2-11 and Preparation Example 1 is that the components added as auxiliary reagents are different, and the masses of the added components are equal, as shown in Table 1. "√" indicates that the component is added.

[0045] Table 1

[0046] Butyl laurate Carboxymethyl cellulose Hydroxyethyl cellulose Hydroxypropyl methylcellulose dimethyl sulfoxide Benzyltrimethylammonium hydroxide Sodium dehydroacetate Preparation Example 1 √ √ √ √ √ √ √ Preparation Example 2 √ Preparation Example 3 √ Preparation Example 4 √ Preparation Example 5 √ Preparation Example 6 √ √ Preparation Example 7 √ √ Preparation Example 8 √ √ Preparation Example 9 √ √ √ Preparation Example 10 √ √ Preparation Example 11 √ Preparation Example 12 √ √ Preparation Example 13 √ √ √ √ Preparation Example 14 √ √ √ Preparation Example 15 √ √ Preparation Example 16 √ √ √ √ √ √ Preparation Example 17 √ √ √ √ √ Preparation Example 18 √ √ √ √ Preparation Example 19 √ √ √ Preparation Example 20 √ √ √ √ √ Preparation Example 21 √ √ √ √ Preparation Example 22 √ √ √ √ √ √ Preparation Example 23 √ √ √

[0047] Example 1

[0048] A cleaning solution comprising the following components in mass ratio:

[0049] 5% anionic surfactant, wherein the anionic surfactant is sodium lauryl sulfate;

[0050] 4% zwitterionic surfactant, wherein the zwitterionic surfactants are cocamidopropyl betaine and lauramidopropyl betaine, and the added masses of the two zwitterionic surfactants are equal;

[0051] Tween-20 is 0.1%;

[0052] 1.5% of auxiliary reagent, and the auxiliary reagent is the auxiliary reagent in Preparation Example 1;

[0053] Water balance.

[0054] Preparation of detergent solution:

[0055] S1: Add auxiliary reagents to water according to the formula and stir evenly;

[0056] S2: Add anionic surfactant and Tween-20 into S1 according to the recipe and stir evenly;

[0057] S3: Add zwitterionic surfactant into S2 according to the recipe and stir evenly.

[0058] Cleaning method using this cleaning solution:

[0059] 1) Place the gold-dotting machine pipe that needs to be cleaned in the detergent and ultrasonically clean it for 5 minutes;

[0060] 2) After the ultrasonic treatment, the cleaned pipe was mounted on the gold-doping machine for a second cleaning. The cleaning sequence included: 10 washes with water, 10 washes with 0.1 mol / L HCl, 10 washes with 0.1 mol / L NaOH, and 10 washes with water. The pipe was then drained after the second cleaning.

[0061] Example 2-3

[0062] The difference between Example 2-3 and Example 1 is that the amount of anionic surfactant added is different. The amount of anionic surfactant added in Example 2 is 4%, and the amount of anionic surfactant added in Example 3 is 7%.

[0063] Examples 4-5

[0064] The difference between Example 4-5 and Example 1 is that the amount of zwitterionic surfactant added is different. The amount of zwitterionic surfactant added in Example 4 is 3%, and the amount of zwitterionic surfactant added in Example 5 is 5%.

[0065] Examples 6-7

[0066] The difference between Example 6-7 and Example 1 is that different zwitterionic surfactants are added. The zwitterionic surfactant added in Example 6 is cocamidopropyl betaine, and the zwitterionic surfactant added in Example 7 is lauramidopropyl betaine.

[0067] Examples 8-9

[0068] The difference between Example 8-9 and Example 1 is that the amount of Tween-20 added is different. The amount of Tween-20 added in Example 8 is 0.05%, and the amount of Tween-20 added in Example 9 is 0.15%.

[0069] Examples 10-11

[0070] The difference between Example 10-11 and Example 1 is that the amount of the auxiliary reagent added is different. The amount of the auxiliary reagent added in Example 10 is 1%, and the amount of the auxiliary reagent added in Example 11 is 2%.

[0071] Examples 12-33

[0072] The difference between Examples 12-33 and Example 1 is that the preparation examples of the added auxiliary reagents are different, see Table 2 for details.

[0073] Table 2

[0074] Example Preparation Example Example 1 Preparation Example 1 Example 12 Preparation Example 2 Example 13 Preparation Example 3 Example 14 Preparation Example 4 Example 15 Preparation Example 5 Example 16 Preparation Example 6 Example 17 Preparation Example 7 Example 18 Preparation Example 8 Example 19 Preparation Example 9 Example 20 Preparation Example 10 Example 21 Preparation Example 11 Example 22 Preparation Example 12 Example 23 Preparation Example 13 Example 24 Preparation Example 14 Example 25 Preparation Example 15 Example 26 Preparation Example 16 Example 27 Preparation Example 17 Example 28 Preparation Example 18 Example 29 Preparation Example 19 Example 30 Preparation Example 20 Example 31 Preparation Example 21 Example 32 Preparation Example 22 Example 33 Preparation Example 23

[0075] Comparative Example 1

[0076] The difference between Comparative Example 1 and Example 1 is that in Comparative Example 1, only water was used to ultrasonically treat the gold-dotting machine pipes and components, and some gold label / latex solution still remained.

[0077] Comparative Example 2

[0078] The difference between Comparative Example 2 and Example 1 is that, in Comparative Example 2, only detergent solution is used to soak the gold-touching machine pipe and its components (because the inner diameter of the gold-touching machine pipe is small, it is not easy to brush the inner wall of the gold-touching machine pipe), the required soaking time is longer, and some gold label / latex solution still remains on the inner wall of the gold-touching machine pipe and its components.

[0079] Comparative Example 3

[0080] The difference between Comparative Example 3 and Example 1 is that no anionic surfactant is added in Comparative Example 4, which has a greater impact on the decontamination effect, and a large amount of color still remains on the inner wall of the gold-dotting machine pipe and its components.

[0081] Comparative Example 4

[0082] The difference between Comparative Example 4 and Example 1 is that no zwitterionic surfactant is added in Comparative Example 5, which also has a great impact on the decontamination effect, and there is still a lot of color remaining on the inner wall of the gold-dotting machine pipe and its components.

[0083] Comparative Example 5

[0084] The difference between Comparative Example 5 and Example 1 is that Tween-20 was not added in Comparative Example 3. When ultrasonication was performed for 5 minutes, small color spots remained on the inner wall of the gold-dotting machine pipe. When the ultrasonication time was extended to 15 minutes, the color spots were significantly reduced.

[0085] Comparative Example 6

[0086] The difference between Comparative Example 6 and Example 1 is that no auxiliary reagent is added in Comparative Example 6.

[0087] Summarize:

[0088] Comparing Example 1 with Comparative Example 1, the difference is that in Comparative Example 1, only water was used to ultrasonically treat the gold-dotting machine pipes and components, and some gold label / latex solution still remained.

[0089] Comparing Example 1 and Comparative Example 2, the difference is that Comparative Example 2 only adopts the immersion method, which requires a longer immersion time, and some gold label / latex solution still remains on the inner wall of the gold-dotting machine pipe and its components.

[0090] Comparing Examples 1-3 and Comparative Example 3, the difference is that the amount of anionic surfactant added is different or not added, and when the addition amount is 4%, 5%, and 7%, they all have good decontamination effects and can remove residual liquid and color on the gold-turning machine pipes and components; when the anionic surfactant is not added, it will have a relatively large impact on the decontamination effect.

[0091] Comparing Example 1, Examples 4-5, and Comparative Example 4, the difference is that the amount of zwitterionic surfactant added is different or not added, and when the addition amount is 3%, 4%, and 5%, it also has a good decontamination effect, and can remove the liquid and color remaining on the gold-turning machine pipe and its components; when the zwitterionic surfactant is not added, it will have a relatively large impact on the decontamination effect.

[0092] Comparing Example 1 with Examples 6-7, the difference lies in the addition of different zwitterionic surfactants. When only cocamidopropyl betaine, only lauramidopropyl betaine, or both cocamidopropyl betaine and lauramidopropyl betaine were added, all demonstrated excellent cleaning effects, effectively removing residual liquid and color from the metal-turning machine pipes and components. Furthermore, cocamidopropyl betaine exhibited a certain thickening and antibacterial effect when combined with sodium lauryl sulfate. Lauramidopropyl betaine also exhibited certain thickening and antibacterial effects when combined with the aforementioned anionic surfactants. Furthermore, lauramidopropyl betaine, in combination with butyl laurate, imparted a pleasant aroma to the cleaning solution.

[0093] Comparing Example 1, Examples 8-9 and Comparative Example 5, the difference is that the amount of Tween-20 added is different or no Tween-20 is added. When the Tween-20 addition amount is 0.05%, 0.10%, and 0.15%, it has a better decontamination effect and can remove the residual liquid and color on the gold-turning machine pipe and its components. When Tween-20 is not added, some obvious color spots or color blocks will remain.

[0094] Comparing Example 1, Examples 10-11, and Comparative Example 6, the difference is that the amount of auxiliary reagent added is different or no auxiliary reagent is added. When the auxiliary reagent is added in an amount of 1%, 1.5%, and 2%, it has a better decontamination effect. When no auxiliary reagent is added, some obvious color spots or blocks will remain at the connection of the gold-turning machine pipe components.

[0095] Comparing Example 1 and Examples 12-33, when butyl laurate is not added, there may be more obvious foam on the surface of the liquid, while when butyl laurate is added, there is relatively less foam; when dimethyl sulfoxide is not added, some obvious color spots or color blocks will also remain at the connection of the gold-turning machine pipe parts, and when dimethyl sulfoxide is added, the color spots and color blocks at the connection of the gold-turning machine pipe parts are also removed. The carboxymethyl cellulose, hydroxyethyl cellulose and hydroxypropyl methylcellulose therein play the role of stabilizing the detergent, enabling the cleaning solution to present a relatively stable and uniform liquid state. Benzyltrimethylammonium hydroxide provides a certain alkaline environment, thereby ensuring the stability of dimethyl sulfoxide, and together with carboxymethyl cellulose, hydroxyethyl cellulose and hydroxypropyl methylcellulose, plays the role of stabilizing the liquid system. Sodium dehydroacetate, as a preservative, has a broad-spectrum antibacterial ability, and sodium dehydroacetate is weakly alkaline in aqueous solution, which can also enhance the overall stability of the detergent solution to a certain extent.

[0096] This specific embodiment is merely an explanation of the present application and is not a limitation of the present application. After reading this specification, those skilled in the art may make non-creative modifications to the present embodiment as needed, but as long as they are within the scope of the present application, they are protected by the patent law.

Claims

1. A pipe cleaner solution for a gold-turning machine, characterized by: It comprises the following ingredients in mass ratio: Anionic surfactant 4~7%; Zwitterionic surfactant 3%~5%; Tween-20 0.05%~0.15%; Auxiliary reagents 1~2%; Water balance; The anionic surfactant is sodium lauryl sulfate; the zwitterionic surfactant is one or more combinations of cocamidopropyl betaine and lauryl amide propyl betaine; The auxiliary reagent is a mixture of butyl laurate, dimethyl sulfoxide, benzyltrimethylammonium hydroxide, sodium dehydroacetate, carboxymethyl cellulose, hydroxyethyl cellulose and hydroxypropyl methyl cellulose, and the added mass of each component is equal.

2. A method for preparing the gold-touching machine pipe cleaning solution according to claim 1, characterized in that: The following steps are involved: S1: Add auxiliary reagents to water and stir evenly; S2: Add anionic surfactant and Tween-20 to S1 and stir evenly; S3: Add zwitterionic surfactant to S2 and stir evenly.

3. A cleaning method for a gold-turning machine pipe cleaner solution as claimed in claim 1, characterized in that: The following steps are involved: 1) placing the metal-turning machine pipe to be cleaned into the cleaning solution of claim 1 and performing ultrasonic cleaning; 2) After the ultrasonic treatment, install the cleaned pipe on the gold-dotting machine for a second cleaning. After the second cleaning, drain the pipe.

4. The cleaning method according to claim 3, wherein: The second washing includes, in order: washing with water 10 times, washing with 0.1 mol / L HCl 10 times, washing with 0.1 mol / L NaOH 10 times, and washing with water 10 times.