An essence with repair and / or anti-wrinkle effects and its preparation method

Abstract

The present invention belongs to the technical field. Specifically, the present invention discloses a serum with repair and / or anti-wrinkle effects and a preparation method thereof, which includes the following components: macromolecular collagen peptide, tetrahydropiperine, polylysine, magnolia bark extract, hydroxypropyl cyclodextrin, arginine, acetyl hexapeptide-8, copper tripeptide-1, thickening agent, preservative, Thermus thermophilus lysate, 1,2-pentanediol, dipotassium glycyrrhizinate, betaine, Heteropanax fragrans leaf extract, repair agent, glycerol, moisturizing agent, water. The serum of the present invention can effectively improve skin relaxation, tighten the skin, reduce wrinkles and smooth fine lines, supplement collagen in the skin, effectively delay skin aging, restore and maintain skin moisture and elasticity, improve the activity of skin cells, promote skin metabolism, and at the same time has a certain anti-allergic and anti-inflammatory effect, and has broad application prospects.

Description

Technical Field

[0001] The present invention relates to the technical field of cosmetics, and particularly relates to a serum having a repair and / or anti-wrinkle effect and a preparation method thereof. Background Art

[0002] With the development of society and the improvement of people's living standards, cosmetics have become an indispensable part of modern people's lives. Among cosmetics, anti-wrinkle and repair cosmetics have always attracted much attention. As people age, the skin gradually shows wrinkles, sagging and other aging-related problems.

[0003] Traditional anti-wrinkle and repair cosmetics usually use some active ingredients, such as collagen, hyaluronic acid, vitamin C, etc., to improve the elasticity and firmness of the skin and reduce the appearance of wrinkles. However, there are still some challenges in improving the anti-wrinkle and repair effects of existing technologies. Some anti-wrinkle and repair products may cause skin discomfort, such as dryness, irritation or allergic reactions, which limits their use.

[0004] Therefore, it is necessary to provide a new and more efficient anti-wrinkle and repair product to solve the above technical problems. In view of this, the present application is proposed. Summary of the Invention

[0005] The present invention provides a serum having a repair and / or anti-wrinkle effect and a preparation method thereof. The serum can effectively improve skin sagging, tighten the skin, reduce wrinkles, smooth fine lines, supplement collagen in the skin, effectively delay skin aging, restore and maintain skin moisture and elasticity, and improve the activity of skin cells, and promote skin metabolism.

[0006] The present invention solves its technical problems by adopting the following technical solutions:

[0007] A serum having a repair and / or anti-wrinkle effect, comprising the following components in parts by mass: 0.01-0.1 part of macromolecular collagen peptide, 0.05-0.2 part of tetrahydropiperine, 0.05-0.2 part of polylysine, 0.1-0.4 part of magnolia bark extract, 0.1-0.5 part of hydroxypropyl cyclodextrin, 0.1-0.5 part of arginine, 0.05-0.5 part of acetyl hexapeptide-8, 0.2-0.4 part of tripeptide-1 copper, 0.2-0.6 part of thickener, 0.2-0.6 part of preservative, 0.2-0.8 part of Thermus thermophilus lysate, 0.2-1 part of 1,2-pentanediol, 0.4-0.8 part of dipotassium glycyrrhizinate, 0.4-1 part of betaine, 0.6-1.2 parts of Schefflera arboricola extract, 1-2 parts of repair agent, 2-8 parts of glycerol, 2-10 parts of moisturizer, 75-90 parts of water.

[0008] The present invention combines the above various raw materials in a specific ratio to prepare a serum with excellent anti-wrinkle and repair effects. The said serum can effectively improve skin relaxation, tighten the skin, reduce wrinkles and smooth fine lines, supplement collagen in the skin, effectively delay skin aging, restore and maintain skin moisture and elasticity, enhance the activity of skin cells, promote skin metabolism, and at the same time has a certain anti-allergic and anti-inflammatory effect, showing broad application prospects.

[0009] Among them, the functions of the main active ingredients of the present invention are as follows:

[0010] Sodium hyaluronate: a moisturizing factor; when applied to the skin surface, it will form a viscoelastic transparent hydrated film, which has good water retention, just like HA naturally present in the intercellular matrix, can increase the moisture content of the skin cutin layer, and the moisture content of the cutin layer is closely related to the maintenance of skin health and the defense function against external stimuli.

[0011] Inositol: (1) Increase the gloss of the skin; (2) Moisturize, its moisturizing ability is equivalent to that of glycerol, and there is no sticky feeling of glycerol when used at high concentrations; (3) Promote penetration, it has good percutaneous permeability and can also promote the penetration of other active ingredients.

[0012] Small molecule collagen: after being absorbed by the skin, it can repair the broken and aging elastic fiber network, restore the elasticity of the skin, make it flexible and full; can quickly fill local depressions, improve relaxation, tighten the skin, reduce wrinkles and smooth fine lines; can delay skin aging, restore and maintain skin moisture and elasticity, and make the skin smooth and delicate.

[0013] β-Glucan: (1) Anti-aging and anti-wrinkle, β-glucan not only has the effect of improving the activity of skin cells and promoting skin metabolism, but also has a strong antioxidant effect on the skin, thus can well delay aging; (2) Anti-allergic, anti-inflammatory and repair the skin, β-glucan can improve skin immunity and accelerate wound healing, thus achieving anti-allergic and anti-inflammatory effects; (3) Moisturizing effect, β-glucan has a strong moisturizing effect, can form a transparent, elastic and breathable film on the skin surface, and lock in skin moisture to achieve high moisturizing.

[0014] Carnosine: By protecting mitochondrial function and reducing the production of ROS, reacting with active substances in the body to protect proteins from glycation.

[0015] Macromolecular collagen peptide: effectively supplement collagen in the skin, can delay skin aging, restore and maintain skin moisture and elasticity, and make the skin smooth and delicate. It can quickly repair and promote cell regeneration, intercept aging, and instantly provide strong water replenishment.

[0016] Acetyl Hexapeptide-8: By inhibiting the release of the neurotransmitter acetylcholine, it reduces muscle contraction, thereby reducing the formation of dynamic wrinkles and expression lines.

[0017] Copper Tripeptide-1: Promotes the production of collagen and elastin, and stimulates the production of glucosamine, helping the skin to restore its natural ability to repair itself, achieving the effect of firming and anti-wrinkle.

[0018] Thermus Thermophilus Lysate: Rich in a large number of bioactive essence components such as amino acids, peptides, nucleic acids, vitamins, glutathione, polyamines (polyamino acids), heat-resistant active enzymes, etc. required by the skin, it can promote the synthesis of collagen, quickly penetrate the skin to provide the nutrients needed by the skin, deeply nourish skin cells, slow down skin aging, and at the same time has excellent skin repair function, can effectively maintain skin moisture, has good percutaneous permeability, and can promote the penetration of other active ingredients.

[0019] As a preferred embodiment of the present invention, it includes the following components in parts by mass: 0.05 part of macromolecular collagen peptide, 0.1 part of tetrahydropiperine, 0.1 part of polylysine, 0.2 part of Magnolia officinalis bark extract, 0.2 part of hydroxypropyl cyclodextrin, 0.2 part of arginine, 0.2 part of Acetyl Hexapeptide-8, 0.3 part of Copper Tripeptide-1, 0.4 part of thickener, 0.5 part of preservative, 0.5 part of Thermus Thermophilus Lysate, 0.5 part of 1,2-pentanediol, 0.5 part of dipotassium glycyrrhizinate, 0.6 part of betaine, 1 part of Heteropanax fragrans leaf extract, 1.55 parts of repair agent, 4 parts of glycerol, 6.15 parts of moisturizer, 82.95 parts of water. Especially when the dosage of each raw material is in this part by mass, the anti-wrinkle effect is better.

[0020] As a preferred embodiment of the present invention, the thickener includes at least one of carbomer, hydroxyethyl cellulose, xanthan gum, sodium polyacrylate, acrylic acid (ester) cross-linked polymer.

[0021] As a preferred embodiment of the present invention, the preservative includes at least one of p-hydroxyacetophenone, diazolidinyl urea, DMDM hydantoin, imidazolidinyl urea, phenoxyethanol, sodium benzoate.

[0022] As a preferred embodiment of the present invention, the repair agent includes small molecule collagen, carnosine, β-glucan and chitosan oligosaccharide; the mass ratio of small molecule collagen, carnosine, β-glucan, chitosan oligosaccharide is (0.05~0.2):(0.05~0.2):(0.3~1):(0.6~1.2). Using such a repair agent can effectively repair the broken and aging elastic fiber network, restore the elasticity of the skin, make it flexible and full, improve relaxation, tighten the skin, reduce wrinkles and smooth out fine lines; it can delay skin aging, restore and maintain skin moisture and elasticity, and make the skin smooth and delicate.

[0023] As a preferred embodiment of the present invention, the humectant includes sodium hyaluronate, inositol, betaine and butanediol; the mass ratio of sodium hyaluronate, inositol, betaine and butanediol is (0.05~0.2):(0.2~0.6):(0.4~0.8):(2~8).

[0024] As a preferred embodiment of the present invention, the method for preparing the extract of Heteropanax fragrans leaves includes the following steps:

[0025] (1) Wash the Heteropanax fragrans leaves, dry them, and pulverize them to 20~200 meshes to obtain Heteropanax fragrans leaf powder;

[0026] (2) Mix the Heteropanax fragrans leaf powder and water evenly, stir at a speed of 400~1000 rpm in a water bath at 40~70 °C for 30~100 minutes, and concentrate to a relative density of 1.10~1.20 to obtain a concentrated solution;

[0027] (3) Add pectinase, β-glucanase, and flavor protease to the concentrated solution, and enzymatically hydrolyze at 40~60 °C for 6~24 h to obtain an enzymatically hydrolyzed solution;

[0028] (4) Mix the enzymatically hydrolyzed solution, ethylhexylglycerin, glycerol, quaternary ammonium salt-73, and water evenly to obtain the extract of Heteropanax fragrans leaves.

[0029] The present invention creatively performs water extraction, enzymatic hydrolysis, and mixing with ethylhexylglycerin, glycerol, and quaternary ammonium salt-73 on the Heteropanax fragrans leaves to prepare an extract of Heteropanax fragrans leaves with good stability and excellent anti-wrinkle, antibacterial, and repair effects.

[0030] The inventors of the present invention have found through research that the prepared extract of Heteropanax fragrans leaves can significantly improve the anti-wrinkle effect, and the anti-wrinkle effects of the extracts of Heteropanax fragrans leaves prepared by different methods are different. The extract of Heteropanax fragrans leaves prepared by the method of the present invention has a better anti-wrinkle effect than the extracts of Heteropanax fragrans leaves prepared by other methods.

[0031] As a preferred embodiment of the present invention, in the step (2), the solid-liquid ratio of the Heteropanax fragrans leaf powder to water is 1 g:(4~10) mL; and / or

[0032] In the step (3), the mass ratio of pectinase, β-glucanase, flavor protease, and the concentrated solution is (0.005~0.02):(0.005~0.02):(0.005~0.02):1.

[0033] As a preferred embodiment of the present invention, in the step (3), the mass ratio of the enzymatically hydrolyzed solution, ethylhexylglycerin, glycerol, quaternary ammonium salt-73, and water is 1:(0.05~0.2):(0.1~0.4):(0.05~0.2):(0.5~2).

[0034] The present invention also provides a method for preparing a serum with repair and / or anti-wrinkle effects, comprising the following steps:

[0035] Add a thickening agent, dipotassium glycyrrhizinate, betaine, glycerol, hydroxypropyl cyclodextrin into water, stir evenly at 65-90 °C, cool down to 30-45 °C, then add macromolecular collagen peptide, tetrahydropiperine, magnolia bark extract, acetyl hexapeptide-8, tripeptide-1 copper, Thermus thermophilus lysate, 1,2-pentanediol, Schefflera arboricola leaf extract, a repair agent, a moisturizing agent, stir evenly, and then add a preservative, polylysine, arginine, stir evenly to obtain a serum with repair and / or anti-wrinkle effects.

[0036] Advantages of the present invention: (1) The serum described in the present invention can effectively improve skin relaxation, tighten the skin, reduce wrinkles and smooth fine lines, supplement the collagen of the skin, effectively delay skin aging, restore and maintain skin moisture and elasticity, improve the activity of skin cells, promote skin metabolism, and at the same time also has a certain anti-allergic and anti-inflammatory effect, and has broad application prospects. Specific embodiments

[0037] To make the objectives, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. Apparently, the described embodiments are some but not all of the embodiments of the present invention. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0038] In the present invention, among the technically characterized described in an open-ended manner, a closed technical solution composed of the listed features is included, and an open technical solution including the listed features is also included.

[0039] In the present invention, regarding the numerical range, unless otherwise specified, the above numerical range is regarded as continuous, and includes the minimum value and the maximum value of this range, as well as each value between such minimum value and maximum value. Further, when the range refers to an integer, each integer between the minimum value and the maximum value of this range is included. In addition, when multiple ranges are provided to describe features or characteristics, these ranges can be combined. In other words, unless otherwise specified, all ranges disclosed herein should be understood to include any and all sub-ranges subsumed therein.

[0040] In the present invention, there is no particular limitation on the specific dispersion and stirring treatment methods.

[0041] The raw materials used in the examples and comparative examples are described as follows:

[0042] Macromolecular collagen peptide: Kangzhiwang Biology.

[0043] Small molecule protein (also known as small molecule hydrolyzed collagen powder): Brand name: Cargill Active Small Molecule Hydrolyzed Collagen Powder.

[0044] Thermus thermophilus lysate: Zhejiang Dean Biotechnology Co., Ltd.

[0045] Heteropanax fragrans (Roxb.) Seem. leaves: Qingping Chinese Medicinal Materials Market.

[0046] Repair agent - 1 includes small molecule collagen, carnosine, β - glucan and chitosan oligosaccharide; the mass ratio of the small molecule collagen, carnosine, β - glucan and chitosan oligosaccharide is 0.1:0.1:0.6:0.8.

[0047] Repair agent - 2 includes small molecule collagen, carnosine, β - glucan and chitosan oligosaccharide; the mass ratio of the small molecule collagen, carnosine, β - glucan and chitosan oligosaccharide is 0.05:0.05:0.3:0.6.

[0048] Repair agent - 3 includes small molecule collagen, carnosine, β - glucan and chitosan oligosaccharide; the mass ratio of the small molecule collagen, carnosine, β - glucan and chitosan oligosaccharide is 0.2:0.2:1:0.6.

[0049] Humectant - 1 includes sodium hyaluronate, inositol, betaine and butanediol; the mass ratio of the sodium hyaluronate, inositol, betaine and butanediol is 0.05:0.5:0.6:5.

[0050] Humectant - 2 includes sodium hyaluronate, inositol, betaine and butanediol; the mass ratio of the sodium hyaluronate, inositol, betaine and butanediol is 0.05:0.6:0.85:2.5.

[0051] Humectant - 3 includes sodium hyaluronate, inositol, betaine and butanediol; the mass ratio of the sodium hyaluronate, inositol, betaine and butanediol is 0.2:0.2:0.6:8.

[0052] Preparation method of Heteropanax fragrans (Roxb.) Seem. leaves extract - 1, comprising the following steps:

[0053] (1) Wash the Heteropanax fragrans (Roxb.) Seem. leaves, dry, and pulverize to 50 meshes to obtain Heteropanax fragrans (Roxb.) Seem. leaves powder;

[0054] (2) Mix the Heteropanax fragrans (Roxb.) Seem. leaves powder and water evenly, stir at 800 rpm in a 50 °C water bath for 60 minutes, and concentrate to a relative density of 1.15 to obtain a concentrated solution;

[0055] The solid - liquid ratio of the Heteropanax fragrans (Roxb.) Seem. leaves powder and water is 1 g:6 mL;

[0056] Among them, the relative density is measured by the pycnometer method;

[0057] (3) Add pectinase, β-glucanase, and flavor protease to the concentrated solution, and enzymatically hydrolyze it at 50 °C for 12 h to obtain an enzymatically hydrolyzed solution;

[0058] The mass ratio of the pectinase, β-glucanase, flavor protease, and concentrated solution is 0.01:0.01:0.01:1;

[0059] (4) Mix the enzymatically hydrolyzed solution, 2-ethylhexyl glycerin, glycerol, quaternary ammonium salt-73, and water evenly to obtain the extract of Heteropanax fragrans (Roxb.) Seem. leaves;

[0060] The mass ratio of the enzymatically hydrolyzed solution, 2-ethylhexyl glycerin, glycerol, quaternary ammonium salt-73, and water is 1:0.1:0.3:0.2:1.4.

[0061] A preparation method of Heteropanax fragrans (Roxb.) Seem. leaf extract-2 (the difference from Heteropanax fragrans (Roxb.) Seem. leaf extract-1 is only that Heteropanax fragrans (Roxb.) Seem. leaf extract-2 is not enzymatically hydrolyzed), includes the following steps:

[0062] (1) Wash the Heteropanax fragrans (Roxb.) Seem. leaves, dry them, and crush them to 50 meshes to obtain Heteropanax fragrans (Roxb.) Seem. leaf powder;

[0063] (2) Mix the Heteropanax fragrans (Roxb.) Seem. leaf powder and water evenly, stir at 800 rpm in a water bath at 50 °C for 60 minutes, and concentrate to a relative density of 1.15 to obtain a concentrated solution;

[0064] The solid-liquid ratio of the Heteropanax fragrans (Roxb.) Seem. leaf powder and water is 1 g:6 mL;

[0065] Among them, the relative density is measured by the pycnometer method;

[0066] (3) Mix the concentrated solution, 2-ethylhexyl glycerin, glycerol, quaternary ammonium salt-73, and water evenly to obtain the extract of Heteropanax fragrans (Roxb.) Seem. leaves;

[0067] The mass ratio of the concentrated solution, 2-ethylhexyl glycerin, glycerol, quaternary ammonium salt-73, and water is 1:0.1:0.3:0.2:1.4.

[0068] A preparation method of Heteropanax fragrans (Roxb.) Seem. leaf extract-3 (the difference from Heteropanax fragrans (Roxb.) Seem. leaf extract-2 is only that quaternary ammonium salt-73 is not added to Heteropanax fragrans (Roxb.) Seem. leaf extract-2), includes the following steps:

[0069] (1) Wash the Heteropanax fragrans (Roxb.) Seem. leaves, dry them, and crush them to 50 meshes to obtain Heteropanax fragrans (Roxb.) Seem. leaf powder;

[0070] (2) Mix the Heteropanax fragrans (Roxb.) Seem. leaf powder and water evenly, stir at 800 rpm in a water bath at 50 °C for 60 minutes, and concentrate to a relative density of 1.15 to obtain a concentrated solution;

[0071] The solid-liquid ratio of the Heteropanax fragrans (Roxb.) Seem. leaf powder and water is 1 g:6 mL;

[0072] Among them, the relative density is obtained by testing with a pycnometer;

[0073] (3) Add pectinase, β-glucanase, and flavor protease to the concentrated solution, and enzymatically hydrolyze at 50 °C for 12 h to obtain an enzymatically hydrolyzed solution;

[0074] The mass ratio of the pectinase, β-glucanase, flavor protease, and concentrated solution is 0.01:0.01:0.01:1;

[0075] (4) Mix the enzymatically hydrolyzed solution, ethylhexylglycerol, glycerol, and water evenly to obtain an extract of Heteropanax fragrans leaves;

[0076] The mass ratio of the enzymatically hydrolyzed solution, ethylhexylglycerol, glycerol, and water is 1:0.1:0.3:1.4.

[0077] Unless otherwise specified, the component raw materials used in the examples and comparative examples of the present invention are all commercially available raw materials, and the component raw materials used in each parallel experiment are of the same kind.

[0078] Examples 1 to 3, Comparative Examples 1 to 8

[0079] The components and mass parts of the essence of the examples and comparative examples are shown in Table 1 (all in mass parts in the table).

[0080] Table 1

[0081]

[0082] The preparation methods of the essence of the examples and comparative examples all include the following steps:

[0083] Add carbomer 980, dipotassium glycyrrhizinate, betaine, glycerol, and hydroxypropyl cyclodextrin to water, stir evenly at 80 °C, cool down to 40 °C, and then add macromolecular collagen peptide, tetrahydropiperine, Magnolia officinalis bark extract, acetyl hexapeptide-8, tripeptide-1 copper, Thermus thermophilus lysate, 1,2-pentanediol, Heteropanax fragrans leaf extract, repair agent, and moisturizer, stir evenly, and then add p-hydroxyacetophenone, polylysine, and arginine, stir evenly to obtain the essence.

[0084] 1. Stability test

[0085] Perform stability tests on Examples 1 to 3 and Comparative Examples 1 to 8. The heat resistance test is to stand still at 45 ± 2 °C for one month, and observe its appearance, color, and smell; the cold resistance test is to stand still at -18 ± 2 °C for one month, and observe its appearance, color, and smell; the thermal cycling test is to store at 45 °C, room temperature, and -18 °C for 24 h each, and cycle 3 times, and observe its appearance, color, and smell. The test results are shown in Table 2.

[0086] Table 2 Stability test results

[0087]

[0088] As can be seen from Table 2, the essence of the present invention has good stability. From the comparison between Example 1 and Comparative Example 7, it can be seen that in the preparation process of the extract of Heteropanax fragrans, adding quaternary ammonium salt-73 significantly improves its stability.

[0089] 2. Anti-wrinkle test

[0090] (1) Volunteer screening: Select 66 volunteers. All volunteers are randomly divided into 11 groups of 6 people each, and the volunteers in each group respectively try the essence of Examples 1-3 and Comparative Examples 1-8.

[0091] The inclusion criteria for volunteers are: aged 20-35 years old, female; those who have not used hormonal drugs and immunosuppressants in the past month; those who have not participated in other clinical trials at the test site now or in the past 30 days; those who can cooperate well with the test; those who can read and understand all the contents of the informed consent form and voluntarily sign the informed consent form; those who agree not to use any cosmetics, drugs and health products that affect the results during the test.

[0092] Exclusion criteria: Those with open wounds or erosive surfaces; those with highly allergic constitutions; those with a history of cosmetic allergies; those with severe heart, liver, and kidney function damage and severe immunodeficiency; those with mental illnesses, severe endocrine diseases, and those taking oral contraceptives; those who have participated in drug clinical trials or other tests within 30 days, or those who have taken systemic drugs that affect the test results within the past week; those who have taken oral and topical beauty products that may affect the test results within 2 weeks; those who the researcher believes are not suitable for participating in this test.

[0093] Termination and withdrawal criteria: Those who do not apply the test sample as required or do not record the follow-up visit as required during the test; those who suffer from serious diseases or have serious adverse reactions during use.

[0094] (2) Test method: After cleansing their faces in the morning and evening every day, the volunteers use the corresponding essence on the whole face for 30 consecutive days.

[0095] Use a skin elasticity tester MPA580 (used according to the instructions or the provided tutorials) to measure the R2 value around the eyes (at the same position before and after the test) before and after use. The closer the R2 value is to 1, the better the anti-wrinkle effect. The test results are shown in Table 3.

[0096] Table 3

[0097]

[0098] As can be seen from Table 1 and Table 3, the essence described in the present invention has excellent anti-wrinkle effects and can effectively improve skin elasticity.

[0099] By comparing Examples 1 to 3, it can be seen that Example 1 is the optimal implementation mode of the present invention. When the raw material dosage is under the conditions of Example 1, the anti-wrinkle effect is the best.

[0100] By comparing Example 1 with Comparative Examples 1 to 3, it can be seen that in the present invention, Heteropanax fragrans leaf extract, Thermus thermophilus lysate, and Tripeptide-1 Copper are all indispensable components. If any one of them is missing, the anti-wrinkle effect will be significantly reduced.

[0101] By comparing Example 1 with Comparative Examples 4 to 6, it can be seen that when the total amount of Heteropanax fragrans leaf extract, Thermus thermophilus lysate, and Tripeptide-1 Copper remains unchanged, the lack of any one of them will lead to a significant reduction in the anti-wrinkle effect.

[0102] By comprehensively comparing Example 1 with Comparative Examples 1 to 6, it can be known that in the present invention, Heteropanax fragrans leaf extract, Thermus thermophilus lysate, and Tripeptide-1 Copper are all indispensable components, and the three have a significant synergistic effect in anti-wrinkle.

[0103] By comparing Example 1 with Comparative Examples 7 to 8, it can be known that the Heteropanax fragrans leaf extract prepared by the present invention can significantly improve the anti-wrinkle effect, and the anti-wrinkle effects of Heteropanax fragrans leaf extracts prepared by different methods are different. The Heteropanax fragrans leaf extract prepared by the method of the present invention has a better anti-wrinkle effect than the Heteropanax fragrans leaf extracts prepared by other methods.

[0104] Taking the above ideal embodiments of the present invention as inspiration, through the above description, relevant staff can completely make various changes and modifications without departing from the technical idea of the present invention. The technical scope of the present invention is not limited to the content in the specification, and its technical scope must be determined according to the scope of the claims.

Claims

1. An essence with repair and / or anti-wrinkle effects, characterized in that, it comprises the following components in parts by mass: 0.01 - 0.1 part of macromolecular collagen peptide, 0.05 - 0.2 part of tetrahydropiperine, 0.05 - 0.2 part of polylysine, 0.1 - 0.4 part of Magnolia officinalis bark extract, 0.1 - 0.5 part of hydroxypropyl cyclodextrin, 0.1 - 0.5 part of arginine, 0.05 - 0.5 part of acetyl hexapeptide-8, 0.2 - 0.4 part of copper tripeptide-1, 0.2 - 0.6 part of thickener, 0.2 - 0.6 part of preservative, 0.2 - 0.8 part of Thermus thermophilus lysate, 0.2 - 1 part of 1,2-pentanediol, 0.4 - 0.8 part of dipotassium glycyrrhizinate, 0.4 - 1 part of betaine, 0.6 - 1.2 parts of Heteropanax fragrans leaf extract, 1 - 2 parts of repair agent, 2 - 8 parts of glycerol, 2 - 10 parts of moisturizer, 75 - 90 parts of water; The preparation method of the Heteropanax fragrans leaf extract comprises the following steps: (1) Wash the Heteropanax fragrans leaves, dry them, and crush them to 20 - 200 meshes to obtain Heteropanax fragrans leaf powder; (2) Mix the Heteropanax fragrans leaf powder and water evenly, stir at a speed of 400 - 1000 rpm in a water bath at 40 - 70 °C for 30 - 100 minutes, and concentrate to a relative density of 1.10 - 1.20 to obtain a concentrated solution; (3) Add pectinase, β-glucanase, and flavor protease to the concentrated solution, and carry out enzymatic hydrolysis at 40 - 60 °C for 6 - 24 h to obtain an enzymatic hydrolysate; (4) Mix the enzymatic hydrolysate, ethylhexylglycerin, glycerol, quaternary ammonium salt-73, and water evenly to obtain the Heteropanax fragrans leaf extract; In the step (2), the solid-liquid ratio of the Heteropanax fragrans leaf powder to water is 1 g : (4 - 10) mL; and / or in the step (3), the mass ratio of pectinase, β-glucanase, flavor protease, and the concentrated solution is (0.005 - 0.02) : (0.005 - 0.02) : (0.005 - 0.02) : 1; In the step (3), the mass ratio of the enzymatic hydrolysate, ethylhexylglycerin, glycerol, quaternary ammonium salt-73, and water is 1 : (0.05 - 0.2) : (0.1 - 0.4) : (0.05 - 0.2) : (0.5 - 2).

2. The essence with repair and / or anti-wrinkle effects according to claim 1, characterized in that, it comprises the following components in parts by mass: 0.05 part of macromolecular collagen peptide, 0.1 part of tetrahydropiperine, 0.1 part of polylysine, 0.2 part of Magnolia officinalis bark extract, 0.2 part of hydroxypropyl cyclodextrin, 0.2 part of arginine, 0.2 part of acetyl hexapeptide-8, 0.3 part of copper tripeptide-1, 0.4 part of thickener, 0.5 part of preservative, 0.5 part of Thermus thermophilus lysate, 0.5 part of 1,2-pentanediol, 0.5 part of dipotassium glycyrrhizinate, 0.6 part of betaine, 1 part of Heteropanax fragrans leaf extract, 1.55 parts of repair agent, 4 parts of glycerol, 6.15 parts of moisturizer, 82.95 parts of water.

3. The essence with repair and / or anti-wrinkle effects according to claim 1, characterized in that, The thickener includes at least one of carbomer, hydroxyethyl cellulose, xanthan gum, sodium polyacrylate, and acrylic acid (ester) cross-linked polymer.

4. The essence with repair and / or anti-wrinkle effects according to claim 1, characterized in that the preservative includes at least one of p-hydroxyacetophenone, diazolidinyl urea, DMDM hydantoin, imidazolidinyl urea, phenoxyethanol, and sodium benzoate.

5. The essence with repair and / or anti-wrinkle effects according to claim 1, characterized in that the repair agent includes small molecule collagen, carnosine, β-glucan, and hydrolyzed chitosan; the mass ratio of small molecule collagen, carnosine, β-glucan, and hydrolyzed chitosan is (0.05 - 0.2):(0.05 - 0.2):(0.3 - 1):(0.6 - 1.2).

6. The essence with repair and / or anti-wrinkle effects according to claim 1, characterized in that the moisturizer includes sodium hyaluronate, inositol, betaine, and butanediol; the mass ratio of sodium hyaluronate, inositol, betaine, and butanediol is (0.05 - 0.2):(0.2 - 0.6):(0.4 - 0.8):(2 - 8).

7. The preparation method of the essence with repair and / or anti-wrinkle effects according to any one of claims 1 - 6, characterized in that it includes the following steps: Adding the thickener, dipotassium glycyrrhizinate, betaine, glycerol, and hydroxypropyl cyclodextrin into water, stirring evenly at 65 - 90 °C, cooling to 30 - 45 °C, then adding macromolecular collagen peptide, tetrahydropiperine, magnolia bark extract, acetyl hexapeptide-8, tripeptide-1 copper, Thermus thermophilus lysate, 1,2-pentanediol, Schefflera arboricola extract, repair agent, and moisturizer, stirring evenly, then adding the preservative, polylysine, and arginine, and stirring evenly to obtain the essence with repair and / or anti-wrinkle effects.

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