Skin care and sterilization wash-free gel and preparation method thereof

Abstract

The present application relates to the technical field of daily chemical products, and specifically discloses a skin care and sterilization free-washing gel and its preparation method. The skin care and sterilization free-washing gel includes the following raw materials in percentage by weight: 1 2% moisturizing agent, 0.5 2% aloe extract, 0.01-0.05% plant essential oil, 0.04 0.07% essence, 0.003 0.08% hypochlorous acid, 0.5 1.5% trisodium phosphate, 4 6% sodium metasilicate, 0.1 1% sodium chloride, and the balance is deionized water. Its preparation method is: aloe extract and deionized water are mixed evenly, hypochlorous acid and moisturizing agent are added, after mixing, plant essential oil and essence are added, after mixing, trisodium phosphate and sodium metasilicate are added, stirred evenly, and pH is adjusted to 5 7. The skin care and sterilization free-washing gel of the present application has the advantages of strong antibacterial, free washing, moisturizing, short drying time, non-sticky feel, and good high and low temperature stability.

Description

Technical Field

[0001] The present application relates to the technical field of daily chemical products, and more specifically, to a skin care and sterilization wash-free gel and a preparation method thereof. Background Art

[0002] Hand washing has always been a crucial part of life. From washing hands before meals to traveling on public transportation and coming into contact with other people and objects, the chances of hand-borne illnesses are increasing. Hand washing and disinfection methods have evolved from soap and perfumed soap to hand sanitizers, achieving increasingly effective and convenient cleaning results.

[0003] In addition to the advantages of traditional hand sanitizers, hand sanitizer gels also overcome the limitation that traditional hand sanitizers require water to use. The ubiquitous "sources of germ transmission" in daily life constantly threaten people's health, so whether hands can be cleaned conveniently, quickly and effectively is a very important issue. However, in many situations, it is inconvenient to use water and it is difficult to wash hands. Therefore, hand sanitizer gels can solve this embarrassing problem very well. Just apply a little, apply it on your hands and let it dry naturally to meet the requirements of hand disinfection. It is especially suitable for hand disinfection needs in places where water is scarce or inconvenient to use, such as office work, taking buses and subways, and outdoor travel.

[0004] At present, the main ingredient of most hand sanitizers is alcohol. 75% alcohol is a broad-spectrum disinfectant with low toxicity, good bactericidal effect, and rapid evaporation, which can meet the basic needs of hand sanitizers. However, high concentrations of alcohol can easily damage the skin of the hands, and alcohol will take away a large amount of moisture when evaporating, causing the skin of the hands to be drier and accelerating skin aging. In order to protect the skin, the alcohol concentration is generally reduced and some skin care ingredients are added. However, the reduction in alcohol concentration will affect the bactericidal effect on the one hand, and on the other hand, it will make the natural evaporation time of the hand sanitizer too long, causing inconvenience to users. Summary of the Invention

[0005] In order to ensure that the hand sanitizer gel can not only ensure the sterilization effect, but also prevent the skin from feeling dry after use, and evaporate in a relatively short time without feeling sticky, the present application provides a skin care and sterilization hand sanitizer gel and a preparation method thereof.

[0006] In the first aspect, the present application provides a skin care and sterilization wash-free gel, which adopts the following technical solution:

[0007] A skin care and sterilization wash-free gel comprises the following raw materials in percentage by weight: 1-2% moisturizer, 0.5-2% aloe extract, 0.01-0.05% plant essential oil, 0.04-0.07% essence, 0.003-0.08% hypochlorous acid, 0.5-1.5% trisodium phosphate, 4-6% sodium metasilicate, 0.1-1% sodium chloride, and the balance is deionized water.

[0008] By adopting the above technical solution, aloe vera extract, moisturizing agent, hypochlorous acid and other raw materials are used to prepare the wash-free gel, in which no alcohol is added, and alcohol volatilization will not take away skin moisture, causing dry skin and aging. The low alcohol concentration will not cause a long evaporation time, thereby achieving the effects of moisturizing the skin, moisturizing, quick drying and non-stickiness; sodium chloride can keep the hands moist, and can also kill bacteria and reduce inflammation, and promote skin metabolism; aloe vera extract has certain effects in moisturizing, reducing inflammation, inhibiting bacteria, relieving itching, and anti-allergic, and can improve skin delicateness, making the skin of the hands smooth and elastic; the moisturizing agent can replenish moisture in the hands after washing, and seal the moisture in the skin to prevent moisture evaporation, maintain skin elasticity, and achieve a good skin care effect.

[0009] Optionally, the moisturizer is selected from at least one of sodium hyaluronate, propylene glycol, jojoba seed oil, camellia extract, allantoin, tea tree oil, and butterfly pea flower extract.

[0010] By adopting the above technical solution, sodium hyaluronate can replenish water and moisturize, keep muscle cells active, accelerate skin metabolism, increase skin elasticity, promote the proliferation and differentiation of epidermal cells, and scavenge oxygen free radicals. It can form a thin film on the skin surface, creating a good smoothness and lubrication, playing a role in protecting the skin, and also has a thickening and stabilizing effect; propylene glycol is refreshing and non-sticky, and can absorb moisture from humid air to maintain the water content of the skin's stratum corneum; jojoba seed oil is rich in vitamin A, vitamin B, calcium, magnesium and other minerals, has good permeability, is a base oil with extremely high stability and good ductility, and its chemical molecular arrangement is very similar to human sebum, which is easily assimilated and absorbed by the skin. It is suitable for all skin types, can unclog pores, regulate the oil content of oily or combination skin, moisturize and hydrate, and increase skin hydration Camellia extract can relieve skin allergy symptoms, and has antibacterial and anti-inflammatory effects. It can also whiten, delay aging, moisturize and have anti-oxidation effects. Allantoin has physiological functions such as promoting tissue growth, cell metabolism, and softening the stratum corneum. It is a good healing agent for skin trauma, can relieve and treat dry skin, and make the skin soft and elastic. Tea tree oil is a colorless or light yellow liquid with a pleasant cardamom smell. It is mild in nature, has good skin permeability, does not irritate the skin, and can effectively inhibit many common pathogenic bacteria and molds. Butterfly pea flower is rich in anthocyanins, vitamins and other substances. Butterfly pea flower extract contains peptides that show antibacterial activity, which can inhibit Escherichia coli, Pseudomonas aeruginosa, etc. It can also delay aging, tighten the skin, promote collagen production, and increase skin elasticity.

[0011] Optionally, the moisturizing agent comprises sodium hyaluronate and propylene glycol in a mass ratio of 1:(0.2-0.7).

[0012] By adopting the above technical solution, sodium hyaluronate and propylene glycol are mixed in the above ratio as a moisturizing agent, which has a good moisturizing effect.

[0013] Optionally, the moisturizer comprises sodium hyaluronate, propylene glycol, jojoba seed oil and butterfly pea flower extract in a mass ratio of 1:(0.2-0.7):(0.2-0.5):(0.1-0.3).

[0014] By adopting the above technical solution, sodium hyaluronate and propylene glycol can improve the moisture content of the skin, replenish water and moisturize. Jojoba seed oil is similar to sebum and can promote the penetration of the wash-free gel, soothe dry skin and lock in moisture. Butterfly pea flower extract can be antibacterial and anti-aging. The combination of these four ingredients can effectively improve the moisturizing effect of the wash-free gel, prevent the skin from drying out after washing, and increase the antibacterial properties of the wash-free gel.

[0015] Optionally, the preparation method of the moisturizing agent comprises the following steps:

[0016] Mix sodium hyaluronate, propylene glycol, butterfly pea flower extract, PEG-40 hydrogenated castor oil and caprylic / capric triglyceride to form phase A;

[0017] Mix jojoba seed oil, glycerin and distilled water and keep in a constant temperature water bath at 45-50°C for 20-30 minutes as phase B;

[0018] Add phase B to phase A, stir for 20-30 minutes, and homogenize at 30-35 MPa to prepare a moisturizing agent.

[0019] By adopting the above technical solution, sodium hyaluronate, propylene glycol and butterfly pea flower extract are mixed with PEG-40 hydrogenated castor oil as an emulsifier and solubilizer, and caprylic / capric triglyceride as a emollient and solvent to form phase A. Jojoba seed oil, glycerin and distilled water are used as phase B. After homogenization, a co-delivery nanocarrier is prepared and loaded with multiple moisturizing ingredients. The co-delivery nanocarrier can achieve synergistic enhancement of multi-target and multi-effect skin care ingredients, promote the penetration of moisturizing ingredients through the stratum corneum, improve the solubility of poorly soluble moisturizing ingredients, and further enhance the moisturizing effect.

[0020] Optionally, the sodium hyaluronate comprises isopropyl myristate, cristata extract and high molecular weight sodium hyaluronate with a molecular weight of 80-150W in a mass ratio of (0.1-0.3):(0.5-1):1.

[0021] By adopting the above technical scheme, the sea fennel extract is rich in monoterpenes, gamma-terpinene, thymol methyl ether volatile oil, pectin, vitamins and minerals, etc., which can deeply moisturize the skin, and the phenolic acid therein has a good ability to scavenge free radicals and inhibit the activity of tyrosinase, thereby achieving the effect of whitening; the high molecular sodium hyaluronate mainly forms a uniform and breathable water film on the surface of the skin, effectively preventing water loss and bacterial infection, and the high molecular sodium hyaluronate and sea fennel extract work together to achieve the effects of surface moisturizing and deep moisturizing, while isopropyl myristate can promote the penetration mechanism of sea fennel extract mainly by acting on the intercellular lipids in the stratum corneum, causing structural changes and increasing lipid fluidity, which has the effect of moisturizing and nourishing the skin, and can promote the absorption of the wash-free gel, accelerate the volatilization of the wash-free gel, and reduce the sticky feeling.

[0022] Optionally, the mass ratio of the PEG-40 hydrogenated castor oil, caprylic / capric triglyceride and sodium hyaluronate is (0.1-0.3):(0.05-0.1):1;

[0023] The mass ratio of jojoba seed oil, glycerin and distilled water is (0.2-0.5):(0.5-1):2.

[0024] By adopting the above technical solution, the raw materials in the above amounts can be made into co-delivery nano-carriers, and the moisturizing ingredients can be loaded on the co-delivery nano-carriers, thereby achieving a synergistic effect of the ingredients.

[0025] Optionally, the skin care and sterilization wash-free gel further includes a stabilizer in an amount of 0.05-0.15% by mass.

[0026] By adopting the above technical solution, the wash-free condensate is very easy to become turbid and hydrated in a low-temperature environment or a high-temperature environment, and its stability is poor. Therefore, a certain proportion of stabilizer is added thereto to improve the stability of the wash-free condensate at high or low temperatures.

[0027] Optionally, the stabilizer comprises corn sprout extract and hydrolyzed corn cellulose in a mass ratio of 0.5-1:1.

[0028] By adopting the above technical scheme, the corn sprout extract is a substance rich in adenine derivatives isolated from vigorously growing corn sprouts. The main component is kinetin, which is an indispensable active substance in animal and plant cells. It can effectively scavenge reactive oxygen free radicals, resist oxidative stress damage caused by UVA irradiation, and delay the aging of skin cells caused by oxidation. It has good cold resistance, heat resistance and storage properties. After the corn cellulose crystals are hydrolyzed, the surface charge of the cellulose particles is increased, the electrostatic repulsion and steric effect between the particles are increased, and the particle agglomeration is reduced. Therefore, the particle size of the hydrolyzed corn cellulose is significantly reduced. After dispersion in the wash-free gel, the hydrogen bonds between the molecular chains are broken after the surface is hydrolyzed, which increases the polar groups and enhances the electronegativity. After the wash-free gel is added, the surface between the droplets has a relative ability to resist aggregation, the droplet dispersibility is improved, the flocculation phenomenon at low and high temperatures is weakened, and the stability is enhanced.

[0029] Optionally, the preparation method of the hydrolyzed corn cellulose is as follows: corn cellulose and sulfuric acid solution are mixed in a solid-liquid ratio of 1:10-11, hydrolyzed at 45-50°C for 1.5-2h, distilled water 10 times the volume of the sulfuric acid solution is added, mixed evenly, centrifuged, washed until neutral, freeze-dried, and ground to make powder; the powder is prepared into a suspension with a mass fraction of 0.8-1% with distilled water, ultrasonically dispersed, and homogenized at 36-40MPa for 5-6min.

[0030] By adopting the above technical solution, polar groups are introduced under the action of sulfuric acid hydrolysis, and as high-pressure homogenization proceeds, cellulose is subjected to various forces, including impact force between particles, shear force, and cavitation force generated by extreme changes in the flow rate of the object, so that some crystalline and non-crystalline regions of the cellulose are broken, the particle size becomes smaller, and the particle size distribution becomes more uniform. Part of the structure is destroyed, the surface is roughened, and the loose and porous structure exposes more active groups, the degree of polymerization is reduced, the polarity is enhanced, the electronegativity is increased, the droplets show relative resistance to aggregation, the droplets have good dispersion, and the flocculation phenomenon gradually weakens; after high-pressure homogenization, the hydrophilicity of the cellulose is improved, and the low-temperature stability of the emulsion is improved.

[0031] Optionally, the plant essential oil is selected from at least one of rose essential oil, chrysanthemum essential oil, tea tree essential oil, and peppermint essential oil;

[0032] The fragrance is selected from at least one of cologne essence, lemon essence, jasmine essence and sweet orange essence.

[0033] In the second aspect, the present application provides a method for preparing a skin care and sterilization wash-free gel, which adopts the following technical solution: a method for preparing a skin care and sterilization wash-free gel, mixing aloe vera extract, sodium chloride and deionized water evenly, adding hypochlorous acid and moisturizer, mixing evenly, adding plant essential oils and essences, mixing evenly, adding trisodium phosphate and sodium metasilicate, stirring evenly, adjusting the pH to 5-7, and making a skin care and sterilization wash-free gel.

[0034] By adopting the above technical solution, the preparation method is simple and the conditions are easy to control.

[0035] In summary, this application has the following beneficial effects:

[0036] 1. Since this application uses aloe vera extract, moisturizer, hypochlorous acid and other components to prepare a wash-free gel, it can effectively kill bacteria on the hands, has little irritation to the skin, and achieves the effects of skin care, hydration and moisturizing, and quick drying. It is an ideal daily disinfection product, especially suitable for wash-free disinfection, sterilization and antibacterial of hands to prevent contact and infectious diseases.

[0037] 2. In this application, sodium hyaluronate, propylene glycol, jojoba seed oil and butterfly pea flower extract are preferably used as moisturizers, so that the hand skin can be moisturized and elastic after use of the wash-free gel.

[0038] 3. In this application, high molecular weight sodium hyaluronate, sea fennel extract and isopropyl myristate are preferably used. Under the promoting penetration of isopropyl myristate, deep nourishment and surface hydration and water lock are achieved, so that the wash-free gel can achieve the effect of hydration and moisturizing while sterilizing.

[0039] 4. In the present application, it is preferred to add corn sprout extract and hydrolyzed cellulose as stabilizers to the wash-free gel, which can increase the stability of the wash-free gel at high and low temperatures and prevent it from becoming turbid and decomposing. DETAILED DESCRIPTION

[0040] Preparation Examples 1-7 of Moisturizing Agents

[0041] Preparation Example 1: 1 kg of sodium hyaluronate, 0.7 kg of propylene glycol, 0.3 kg of butterfly pea flower extract, 0.3 kg of PEG-40 hydrogenated castor oil, and 0.1 kg of caprylic / capric triglyceride were uniformly mixed to form phase A. The sodium hyaluronate included isopropyl myristate, cristae cristae extract, and high molecular weight sodium hyaluronate with a molecular weight of 150W in a mass ratio of 0.3:1:1;

[0042] 0.5 kg of jojoba seed oil, 1 kg of glycerin and 2 kg of distilled water were mixed and kept in a constant temperature water bath at 50° C. for 30 minutes to prepare phase B. Phase B was added to phase A, stirred for 30 minutes, and homogenized at 30 MPa for 5 minutes to prepare a moisturizer.

[0043] Preparation Example 2: 1 kg of sodium hyaluronate, 0.2 kg of propylene glycol, 0.1 kg of butterfly pea flower extract, 0.1 kg of PEG-40 hydrogenated castor oil, and 0.05 kg of caprylic / capric triglyceride were uniformly mixed to form phase A. The sodium hyaluronate included isopropyl myristate, cristae cristae extract, and high molecular weight sodium hyaluronate with a molecular weight of 80W in a mass ratio of 0.1:0.5:1;

[0044] 0.2 kg of jojoba seed oil, 0.5 kg of glycerin and 2 kg of distilled water were mixed and kept in a constant temperature water bath at 45° C. for 20 minutes to prepare phase B. Phase B was added to phase A, stirred for 20 minutes, and homogenized at 35 MPa for 3 minutes to prepare a moisturizer.

[0045] Preparation Example 3: The difference from Preparation Example 1 is that allantoin is used instead of butterfly pea flower extract.

[0046] Preparation Example 4: The difference from Preparation Example 1 is that tea tree oil is used instead of jojoba seed oil.

[0047] Preparation Example 5: The difference from Preparation Example 1 is that isopropyl myristate and cristata foeniculum vulgare extract are not added to sodium hyaluronate.

[0048] Preparation Example 6: The difference from Preparation Example 1 is that sodium hyaluronate includes isopropyl myristate and high molecular weight sodium hyaluronate with a molecular weight of 150W in a mass ratio of 0.3:1.

[0049] Preparation Example 7: The difference from Preparation Example 1 is that the sodium hyaluronate includes the sea fennel extract and the high molecular weight sodium hyaluronate with a molecular weight of 150W in a mass ratio of 1:1.

[0050] Example

[0051] Example 1: A skin care and sterilization wash-free gel, the raw material amounts are shown in Table 1, wherein the plant essential oil is rose essential oil, the essence is cologne essence, and the moisturizer includes sodium hyaluronate and propylene glycol in a mass ratio of 1:0.7, and the molecular weight of sodium hyaluronate is 80W.

[0052] The preparation method of the above-mentioned skin care and sterilization wash-free gel comprises the following steps:

[0053] Mix aloe vera extract, sodium chloride and deionized water evenly, add hypochlorous acid and moisturizer, mix well, add plant essential oils and essence, mix well, add trisodium phosphate and sodium metasilicate, stir well, adjust the pH to 7, and make a skin care and sterilization wash-free gel.

[0054] Table 1 Amount of raw materials used in the skin care and sterilization free wash gel in Examples 1-3 and Example 11

[0055] raw material / % Example 1 Example 2 Example 3 Example 11 moisturizer 2 1.5 1 2 Aloe vera extract 2 1 0.5 2 essential oils 0.05 0.03 0.01 0.05 essence 0.07 0.05 0.04 0.07 Hypochlorous acid 0.08 0.04 0.003 0.08 Trisodium phosphate 1.5 1 0.5 1.5 Sodium metasilicate 6 5 4 6 Sodium chloride 1 0.8 0.5 0.1 stabilizer 0 0 0 1.5 Deionized water margin margin margin margin

[0056] Example 2: A skin care and sterilization wash-free gel. The difference from Example 1 is that the raw material amounts are as shown in Table 1, the moisturizer includes sodium hyaluronate and propylene glycol in a mass ratio of 1:0.2, and the molecular weight of sodium hyaluronate is 150W.

[0057] Example 3: A skin care and sterilization wash-free gel. The difference from Example 1 is that the amounts of raw materials used are as shown in Table 1.

[0058] Example 4: A skin care and sterilization wash-free gel, which is different from Example 1 in that the moisturizer is prepared by Preparation Example 1.

[0059] Example 5: A skin care and sterilization wash-free gel, which differs from Example 1 in that the moisturizer is prepared by Preparation Example 2.

[0060] Example 6: A skin care and sterilization wash-free gel, which differs from Example 1 in that the moisturizer is made from Preparation 3.

[0061] Example 7: A skin care and sterilization wash-free gel, which is different from Example 1 in that the moisturizer is prepared by Preparation Example 4.

[0062] Example 8: A skin care and sterilization wash-free gel, which differs from Example 1 in that the moisturizer is prepared by Preparation Example 5.

[0063] Example 9: A skin care and sterilization wash-free gel, which differs from Example 1 in that the moisturizer is prepared by Preparation Example 6.

[0064] Example 10: A skin care and sterilization wash-free gel, which differs from Example 1 in that the moisturizer is prepared by Preparation Example 7.

[0065] Example 11: A skin care and sterilization wash-free gel, which differs from Example 4 in that the amounts of raw materials used are as shown in Table 1, and the stabilizer is hydrogenated lecithin;

[0066] The preparation method of the above-mentioned skin care and sterilization wash-free gel comprises the following steps:

[0067] Mix aloe vera extract and deionized water evenly, add hypochlorous acid, moisturizer and stabilizer, mix well, add plant essential oil and essence, mix well, add trisodium phosphate and sodium metasilicate, stir well, adjust the pH to 7, and make a skin care and sterilization wash-free gel.

[0068] Example 12: A skin care and sterilization wash-free gel, which differs from Example 11 in that the stabilizer includes corn sprout extract and hydrolyzed corn cellulose in a mass ratio of 1:1, and the preparation method of hydrolyzed corn cellulose is as follows: corn cellulose and 1 mol / l sulfuric acid solution are mixed in a material-liquid ratio of 1:10, hydrolyzed at 50°C for 1.5 hours, distilled water 10 times the volume of the sulfuric acid solution is added, mixed evenly, centrifuged, washed to neutrality, freeze-dried, and ground to make powder; the powder is prepared into a suspension with a mass fraction of 1% with distilled water, ultrasonically dispersed, and homogenized at 40MPa for 5 minutes.

[0069] Example 13: A skin care and sterilization wash-free gel, which differs from Example 11 in that the stabilizer includes corn sprout extract and hydrolyzed corn cellulose in a mass ratio of 1:0.5, and the preparation method of hydrolyzed corn cellulose is as follows: corn cellulose and 1 mol / l sulfuric acid solution are mixed in a material-liquid ratio of 1:11, hydrolyzed at 45°C for 2 hours, 10 times the volume of distilled water of the sulfuric acid solution is added, mixed evenly, centrifuged, washed to neutrality, freeze-dried, and ground to make powder; the powder is prepared into a suspension with a mass fraction of 0.8% with distilled water, ultrasonically dispersed, and homogenized at 36 MPa for 6 minutes.

[0070] Example 14: A skin care and sterilization wash-free gel, which differs from Example 12 in that the stabilizer is corn sprout extract.

[0071] Example 15: A skin care and sterilization wash-free gel, which differs from Example 12 in that the stabilizer is hydrolyzed corn cellulose.

[0072] Comparative Example

[0073] Comparative Example 1: A skin care and sterilization wash-free gel, which differs from Example 1 in that no moisturizer is added.

[0074] Comparative Example 2: A skin care and sterilization wash-free gel, which differs from Example 1 in that no aloe vera extract is added.

[0075] Comparative Example 3: A hand-protecting, wash-free disinfectant gel comprises the following raw materials in the following mass ratios: 0.1% bactericide, 2.1% cosolvent, 0.10% thickener, 0.01% emollient, 1.8% fragrance, 0.02% pH regulator, 39% ethanol, and the balance is water.

[0076] The method for preparing the hand-protecting, wash-free disinfectant gel can be carried out according to the following steps:

[0077] (1) Weigh each component in proportion, add 30% of the total weight of water to a stainless steel reaction pot, slowly add the thickener in three portions while stirring, and mechanically stir at 90 r / min for 120 minutes until a uniform turbid dispersion is obtained. Let it stand overnight to fully swell, thereby preparing Liquid A.

[0078] (2) In another stainless steel reaction pot, add 30% ethanol to the hand disinfectant solution, then add the bactericide and cosolvent, mix and dissolve, and mechanically stir at a speed of 60 r / min for 8 minutes until the solution is clear to obtain Solution B, which is sealed and stored for future use;

[0079] (3) Pour liquid B into liquid A, add the remaining ethanol, stir at a speed of 60r / min, then add emollient, fragrance and remaining water, and pH adjuster to pH 6.0.

[0080] Comparative Example 4: disinfectant alcohol with a concentration of 75%.

[0081] Performance testing

[0082] The wash-free gel was prepared according to the methods in the examples and comparative examples, and the performance of the wash-free gel was tested according to the following method. The test results are recorded in Table 2.

[0083] 1. Antibacterial rate: According to GB15979-2002 "Hygienic Standard for Disposable Sanitary Products", the 6th generation of Escherichia coli (ATCC8099) was treated with a 1:1 dilution for 2 minutes, and the 6th generation of Staphylococcus aureus (ATCC6538) was treated with a 1:1 dilution for 2 minutes.

[0084] 2. Quick-drying test: Take 1 ml of the disposable gel and evenly apply it on the user's palm. Start timing from the time the gel is evenly applied until the gel on the hand is completely dry. Each group has 10 people, and the test results are averaged. The test temperature is room temperature.

[0085] 3. Hydrating and Moisturizing Effect: Ten female test subjects were selected from each group. A 2-square-centimeter area was drawn on the back of their hands. In an indoor environment at 20°C and 50% relative humidity, the moisture content of the backs of the hands of each group of ten female test subjects was measured using a skin moisture meter. The results were expressed as a set moisture measurement value (MMV). The final MMV value was averaged to evaluate the hydrating and moisturizing performance of the product. Where: MMV0—MMV value before handwashing with the handwash gel; MMV1—MMV value two hours after handwashing with the handwash gel; Moisturizing Ratio = MMV1 / MMV0 × 100%.

[0086] 4. Stability: (1) High temperature stability: Place the sample at 70°C for 5 hours and observe whether there is stratification or sedimentation. If there is no obvious stratification or sedimentation after 5 hours at 70°C, it indicates good high temperature stability; otherwise, it indicates poor high temperature stability.

[0087] (2) Low temperature stability test method: Place the test sample at -20℃ for 2 hours and observe whether there is stratification or sedimentation. If there is no obvious stratification or sedimentation after placing it at -20℃ for 2 hours, it indicates that the low temperature stability is good; otherwise, it indicates that the low temperature stability is poor.

[0088] Table 2 Performance test results of skin care and sterilization free washing gel

[0089]

[0090]

[0091] Combining the contents of Example 2 with Examples 1-3, it can be seen that the wash-free gel prepared in Examples 1-3 has a good antibacterial effect, a fast evaporation rate, does not produce a sticky feeling, has a good moisturizing effect, and is not easy to cause skin dryness, but still has the problem of poor stability.

[0092] In Example 4 and Example 5, the moisturizers prepared in Preparation Example 1 and Preparation Example 2 were used respectively. Compared with Example 1, the antibacterial rate of the wash-free gel prepared in Example 4 and Example 5 was increased, and the moisturizing rate was improved, but the stability improvement effect was not obvious.

[0093] Example 6 uses the moisturizing agent prepared in Preparation Example 3. Compared with Preparation Example 1, allantoin is used instead of butterfly pea flower extract. Table 2 shows that compared with Example 4, the antibacterial rate is reduced and the moisturizing rate is weakened, but it is still better than the effect of Example 1.

[0094] In Example 7, the moisturizer prepared in Preparation Example 4 was used, in which tea tree oil was used instead of jojoba seed oil. Table 2 shows that compared with Example 4, the antibacterial rate of the wash-free gel prepared in Example 7 was increased, but the moisturizing rate was lower than that of Example 4.

[0095] In Example 8, the moisturizer prepared in Preparation Example 5 was used, wherein the sodium hyaluronate contained only high molecular weight sodium hyaluronate. In Example 9 and Example 10, the moisturizers prepared in Preparation Examples 6 and Preparation Examples 7 were used, respectively, and no sea fennel extract and isopropyl myristate were added in Preparation Examples 6 and 7, respectively. In Example 9 and Example 10, wash-free gels were prepared, and the moisturizing effect was better than that of Example 8, but still weaker than that of Example 4. In addition, the volatilization time of the wash-free gels in Examples 8 and 10 was increased.

[0096] Compared with Example 4, Example 11 further adds a stabilizer. Table 2 shows that the stability of the wash-free gel prepared in Example 11 at high and low temperatures is improved.

[0097] Compared with Example 4, Example 12 and Example 13 use corn sprout extract and hydrolyzed corn cellulose as stabilizers. By comparison, it can be seen that the wash-free gels prepared in Example 12 and Example 13 have good stability at high and low temperatures, and are more stable than that in Example 11.

[0098] Compared with Example 12, Example 13 and Example 14 did not add hydrolyzed corn cellulose and corn sprout extract, respectively. As shown in Table 2, the high-temperature stability and low-temperature stability of the disposable gel were significantly reduced.

[0099] Compared with Example 1, Comparative Examples 1 and 2 did not add moisturizer and aloe extract respectively. The moisturizing rate of the wash-free gel prepared in Comparative Example 1 was significantly reduced, and the wash-free gel prepared in Comparative Example 2 not only had a decreased moisturizing ability, but also a weakened antibacterial effect.

[0100] Comparative Example 3 is a wash-free product in the prior art, which has a poor antibacterial rate and insufficient moisturizing properties. Comparative Example 4 is a high-concentration ethanol. Although it has a good antibacterial effect and a short volatilization time, it has poor moisturizing properties and can easily cause dry skin.

[0101] The wash-free gels prepared in Examples 1, 4, and 12 were tested in accordance with Part 2, "Technical Specifications for Toxicological Experiments of Disinfectant Products," of the "Technical Specifications for Disinfection" (2002 edition) issued by the Ministry of Health of the People's Republic of China. The results showed that the average total score of the gels prepared in Examples 1, 4, and 12 was 0.09 after multiple intact skin irritation tests on rabbits, with a skin irritation index of 0 to 0.5, indicating that the irritation intensity was non-irritating.

[0102] This specific embodiment is merely an explanation of the present application and is not a limitation of the present application. After reading this specification, those skilled in the art may make non-creative modifications to the present embodiment as needed, but as long as they are within the scope of the claims of the present application, they are protected by the patent law.

Claims

1. A skin care and sterilization wash-free gel, characterized in that: The invention comprises the following raw materials in percentage by weight: 1-2% moisturizing agent, 0.5-2% aloe vera extract, 0.01-0.05% plant essential oil, 0.04-0.07% essence, 0.003-0.08% hypochlorous acid, 0.5-1.5% trisodium phosphate, 4-6% sodium metasilicate, 0.1-1% sodium chloride, and the balance is deionized water; The moisturizing agent comprises sodium hyaluronate, propylene glycol, jojoba seed oil and butterfly pea flower extract in a mass ratio of 1: (0.2-0.7): (0.2-0.5): (0.1-0.3); The sodium hyaluronate comprises isopropyl myristate, cristata extract and high molecular weight sodium hyaluronate with a molecular weight of 80-150W in a mass ratio of (0.1-0.3): (0.5-1): 1; The skin care and sterilization wash-free gel also includes a stabilizer with a mass percentage of 0.05-0.15%, and the stabilizer includes corn sprout extract and hydrolyzed corn cellulose with a mass ratio of 0.5-1:

1.

2. The skin care and sterilization free-washing gel according to claim 1, characterized in that: The preparation method of the moisturizing agent comprises the following steps: Mix sodium hyaluronate, propylene glycol, butterfly pea flower extract, PEG-40 hydrogenated castor oil and caprylic / capric triglyceride to form phase A; Mix jojoba seed oil, glycerin and distilled water and keep in a constant temperature water bath at 45-50°C for 20-30 minutes as phase B; Add phase B to phase A, stir for 20-30 minutes, and homogenize at 30-35 MPa to prepare a moisturizing agent.

3. The skin care and sterilization wash-free gel according to claim 1, characterized in that: The plant essential oil is selected from at least one of rose essential oil, chrysanthemum essential oil, tea tree essential oil and peppermint essential oil; The fragrance is selected from at least one of cologne essence, lemon essence, jasmine essence and sweet orange essence.

4. The method for preparing the skin care and sterilization free-washing gel according to any one of claims 1 to 3, characterized in that: The following steps are involved: Mix aloe vera extract, sodium chloride and deionized water evenly, add hypochlorous acid, moisturizer and stabilizer, mix well, add plant essential oil and essence, mix well, add trisodium phosphate and sodium metasilicate, stir well, adjust the pH to 5-7, and make a skin care and sterilization wash-free gel.

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