Biomedical sample multi-channel friction access system

Abstract

A biological medicine sample multi-channel friction access system comprises, from top to bottom, a sample bottle friction access mechanism, a sample bottle storage unit, an automatic sealing mechanism, a gas conveying mechanism and a transition transfer mechanism, which are sequentially arranged from top to bottom. The sample bottle friction access mechanism, the sample bottle storage unit, the automatic sealing mechanism and the gas conveying mechanism are sequentially arranged from top to bottom. The sample bottle friction access mechanism comprises a support, a sample bottle access unit and a sample bottle access driving mechanism. The sample bottle access driving mechanism drives the sample bottle transfer channel or the sample bottle storage channel in the sample bottle access unit to be docked with the sample bottle storage unit, or drives the sample bottle storage channel to be docked with the transition transfer mechanism. Each part constitutes a closed sample bottle storage and access system in a temperature control box. The sample bottle containing samples is stored in the sample bottle storage unit. The system realizes closed and efficient storage and batch rapid extraction of samples in an ultra-low temperature environment.

Description

Technical Field

[0001] This invention relates to a device for sample storage in the biomedical field, belonging to the field of sample storage technology. Background Technology

[0002] Drug screening is typically conducted independently by researchers, each of whom maintains a large inventory of compounds and needs to exchange compounds or information with other researchers. The process involves preserving and managing thousands of valuable compounds or biological samples. Therefore, sample safety, sample tracking, data traceability, and ensuring access to accurate samples when needed are critical concerns for laboratory managers today.

[0003] The quality of samples is primarily affected by storage temperature, humidity, and time. This is especially true for items with stringent storage requirements, where even minor changes in the storage environment can impact their quality. Some samples are hard-won, and their loss or spoilage can cause irreparable damage. The safe storage and management of samples is a critical issue that urgently needs to be addressed, particularly the scientific management of samples in laboratories, which is crucial for the rapid development and orderly operation of the entire laboratory. Currently, there is a lack of unified management standards for sample information, resulting in a fragmented approach that is incompatible with high-throughput drug screening and severely hinders drug development efficiency.

[0004] Samples generally need to be stored in a frozen or refrigerated environment, and will also be taken out of the frozen or refrigerated environment. In either case, the door of the refrigerated environment (such as a refrigerator or freezer) needs to be opened. Sometimes this is done frequently, which causes air convection between the inside and outside, causing fluctuations in the refrigerated environment (temperature, humidity, etc.) and affecting the stability of the storage environment.

[0005] The quality of stored samples is mainly affected by storage temperature, humidity, and time, especially for items with stringent storage requirements, where even minor changes in the storage environment can affect their quality. Currently, storage methods still rely on traditional refrigerators or freezers. These methods involve repeated freezing and humidity fluctuations, which can easily degrade samples. Furthermore, the need for extensive searching during storage increases the risk of samples being missed. Additionally, there is a lack of standardized procedures for sample characterization and usage records.

[0006] Chinese patent document CN201504517U discloses a "tissue sample storage drawer," which includes at least one drawer frame, each drawer frame containing at least one drawer with a handle, and at least one drawer containing equidistant intervals; the remaining drawers have perforated plates with positioning feet on their lower surface that are embedded in the drawers, and the perforated plates have circular holes. Although this storage drawer can store a certain number of samples, the number of samples that can be stored is still limited, and it is inconvenient to operate and search, and it is not easy to achieve automatic storage and retrieval.

[0007] CN102303763A discloses a "Honeycomb Composite Rotary Sample Storage Device," which includes a vertical shaft, sample storage disks, and a disk drive mechanism. The sample storage disks are mounted parallel to each other on the same vertical shaft. Sample cells and sample transfer channels are distributed on the sample storage disks. Each sample storage disk is connected to a disk drive mechanism, and each disk drive mechanism is mounted on a bracket fixed to the bottom of the vertical shaft. The sample cells are arranged in a ring shape, with at least two rings, all concentric, and each ring has at least one sample transfer channel. While this device solves the shortcomings of current sample storage methods by allowing it to be placed in a sealed storage environment and utilizing refrigeration, pneumatic, sensing, barcode recognition, database management, and network communication technologies to achieve automatic sample storage and intelligent data management, it suffers from the problem that "the vertical shaft and sample storage disks cannot adapt to ultra-low temperature environments, and the disk drive mechanism, especially the electrical system, has limited temperature adaptability," thus preventing it from operating in ultra-low temperature environments. Summary of the Invention

[0008] This invention addresses the shortcomings of existing sample storage technologies by providing a multi-channel triboelectric storage system for biomedical samples with large capacity and the ability to rapidly and batch-store samples in ultra-low temperature environments.

[0009] The multi-channel friction storage system for biomedical samples of the present invention adopts the following technical solution:

[0010] The system includes, from top to bottom, a sample bottle friction storage and retrieval mechanism, a sample bottle storage unit, an automatic sealing mechanism, a gas delivery mechanism, and a transition transfer mechanism, arranged sequentially from top to bottom.

[0011] The sample bottle friction storage and retrieval mechanism includes a support, a sample bottle storage and retrieval unit, and a sample bottle storage and retrieval drive mechanism. The sample bottle storage and retrieval drive mechanism is mounted on the support (the sample bottle storage and retrieval unit operates under the drive of the storage and retrieval drive mechanism). The sample bottle storage and retrieval unit includes a sample bottle transport mechanism and a transport pipe, with the transport pipe connected to the sample bottle transport mechanism. The sample bottle transport mechanism includes a support, a sample bottle transfer chamber, a transport belt, pulleys, and a servo motor. Two pulleys are mounted on the support, one of which is connected to the servo motor. The transport belt is mounted on the two pulleys and inlaid with... Embedded in the sample bottle transfer chamber; the transport pipeline includes a sample bottle inlet channel, an inlet high-pressure gas pipeline, a sample bottle outlet channel, an outlet high-pressure gas pipeline, a sample bottle transfer channel, and a transfer high-pressure gas pipeline, each high-pressure gas pipeline is equipped with a control valve; at least one sample bottle storage and retrieval drive mechanism is provided, which drives the sample bottle transfer channel or the sample bottle inlet channel to connect with the sample bottle storage unit (specifically, the storage tube in the sample bottle storage unit), or drives the sample bottle outlet channel to connect with the transition transfer mechanism (specifically, the sample bottle transfer tube in the transition transfer mechanism).

[0012] Furthermore:

[0013] The sample bottle transfer chamber is equipped with three identification devices, two of which are symmetrically arranged. These three devices can simultaneously capture information from the bottle cap, body, and bottom, ensuring accurate reading of the sample bottle information.

[0014] The sample bottle inlet channel and the inlet high-pressure gas pipeline are symmetrically arranged on the sample bottle transfer chamber; the sample bottle outlet channel and the outlet high-pressure gas pipeline are symmetrically installed on the sample bottle transfer chamber.

[0015] The sample bottle storage and retrieval drive mechanism includes a main drive mechanism and a secondary drive mechanism, with the secondary drive mechanism connected to the power output end of the main drive mechanism. The main drive mechanism employs a lead screw and nut pair moving mechanism. The secondary drive mechanism employs an electric telescopic gripper, including an electric telescopic frame and a gripper. The electric telescopic frame is connected to the power output end of the main drive mechanism, and the gripper is connected to the end of the electric telescopic frame.

[0016] The sample bottle storage unit adopts a bundled tube structure, including a sealed box. A refrigerant exchange port is provided on the side wall of the sealed box. Storage tubes are vertically distributed inside the sealed box. The storage tubes are fixed by tube plates at the upper and lower ends of the sealed box. Both the upper and lower ends of the storage tubes are open.

[0017] The automatic sealing mechanism includes a heat insulation frame and an upper partition, a middle partition, and a lower partition connected from top to bottom within the heat insulation frame. The upper partition has upper through holes with ventilation grooves engraved on their inner walls. The middle partition has circular through holes, each containing a sealing ball; the diameter of the circular through hole is larger than the diameter of the sealing ball. The lower partition has lower through holes. The diameter of the sealing ball is smaller than the inner diameter of the circular through hole but larger than the inner diameters of the upper and lower through holes. The distribution of the upper, circular, and lower through holes is consistent with the distribution of the storage tubes in the sample bottle storage unit. An arc-shaped spherical surface can be provided at the upper end of the lower through hole, with the diameter of the arc-shaped spherical surface not larger than the diameter of the sealing ball.

[0018] The gas delivery mechanism includes a frame, a gas delivery nozzle, a gas storage chamber, a gas delivery channel, and a transmission device. The transmission device is mounted on the frame, the gas storage chamber is connected to the transmission device, the gas delivery nozzle is connected to the gas storage chamber via a control valve, and the gas delivery channel is connected to the gas storage chamber. Gas is delivered into the gas storage chamber through the gas delivery channel. The transmission device drives the gas storage chamber to move, causing the gas delivery nozzle to align with the sealing mechanism (specifically, the lower through hole on the lower partition).

[0019] The transition transfer mechanism includes a sample bottle transfer tube, a sample bottle inlet / outlet, a transition transfer chamber, and a gas delivery pipe. The sample bottle transfer tube is connected above the transition transfer chamber. The transition transfer chamber contains a three-dimensional moving platform, a transition chamber, a sample bottle tray, and a transfer bracket. The transfer bracket is installed at the power output end of the three-dimensional moving platform. The transition chamber includes a frame and a tray. The tray is fixed in the frame, and the sample bottle tray is placed on the tray. The gas delivery pipe is located on the side wall of the transition chamber, with one end inside the chamber opposite the port of the sample bottle transfer tube, and the other end connected to a gas delivery mechanism (specifically, a gas delivery nozzle within the gas delivery mechanism). The sample bottle tray has a sample bottle placement hole on its body, and a transport slot at the bottom. The sample bottle placement hole is a stepped through-hole with a larger diameter at the top and a smaller diameter at the bottom. The sample bottle is placed at the top of the sample bottle placement hole, and the bottom of the hole is used for gas entry to blow the sample bottle out. The transfer tray is equipped with a transport claw, which has an air guide hole (when the sample bottle tray is placed on the transfer tray, the air guide hole corresponds to the sample bottle placement hole above it). When the sample bottle tray is transferred, the transport claw is inserted into the transport slot, and the gas enters the sample bottle placement hole through the through hole on the transport claw, blowing the sample bottle out.

[0020] The entire system is placed within the environment required for sample storage, forming a closed sample bottle storage and retrieval system. The sample bottles containing the samples are stored in the sample bottle storage unit. The process of storing, retrieving, and storing the sample bottles is completed through the combined action of the sample bottle friction storage and retrieval mechanism, the automatic sealing mechanism, the gas supply mechanism, and the transition transfer mechanism.

[0021] This invention has the following characteristics:

[0022] 1. In the sample bottle storage and retrieval unit, a transport belt is set up. The transport belt is embedded in the sample bottle transfer chamber groove and forms a closed cavity with the sample transfer chamber. The transport belt has a certain roughness. Under the action of friction, the sample bottles move in an orderly manner with the transport belt.

[0023] 2. Multiple sample bottle transfer channels are set up in the sample bottle storage and retrieval unit, which can realize the simultaneous entry of multiple sample bottles into the sample transfer chamber, thus improving the storage and retrieval speed.

[0024] 3. Set up a lateral high-pressure gas inlet (relative to the direction of entry) in the sample transfer chamber to provide lateral thrust to the sample bottles entering the chamber, allowing the sample bottles to open the inlet quickly, making way for the entry of subsequent sample bottles. At the same time, it also plays an auxiliary role in lateral thrust, correcting the tilting of sample bottles and preventing blockage caused by the tilting of individual sample bottles.

[0025] 4. A pair of identification devices are symmetrically installed, which can simultaneously capture information from the bottle cap and the bottom of the sample bottle, or prevent the phenomenon of missing sample bottles when only the bottle cap has sample bottle information and the bottle caps are not facing the same direction when the sample bottles are placed in the chamber.

[0026] 5. A third identification device was installed to capture the information on the sample bottle body. By comparing the information on the bottle cap with that on the bottle body, the accuracy of the sample bottle information was ensured. At the same time, sample bottles with abnormal information were also removed to ensure that the information of the sample bottles stored in the storage unit was accurate.

[0027] 6. Multiple sample bottle storage and retrieval drive mechanisms are set up, and a secondary drive mechanism is installed on the main drive mechanism, which can perform multiple target tasks simultaneously, improve system efficiency, and enhance the system's flexibility.

[0028] 7. Placing the storage tube in a sealed box allows the sample vials to enjoy a unique temperature and humidity storage environment, meeting the environmental requirements for sample storage. At the same time, it can also create a lower storage temperature environment to meet the specific sample storage requirements.

[0029] 8. Placing the storage tube in a sealed box prevents heat leakage, facilitating the creation of a storage environment below -25°C. This allows the use of conventional materials, devices, components, and mechanisms, reducing equipment costs and improving safety and reliability. It meets the requirements for conventional actuators operating in environments above -25°C (>-25°C).

[0030] 9. The automatic sealing mechanism achieves self-efficient sealing by relying on the mass of the sealing ball and the principle of universal gravitation, thereby improving the stability and reliability of the system.

[0031] 10. The transition and transfer mechanism is equipped with multiple trays and a three-dimensional moving platform, which allows the sample bottle tray to move in the X, Y, and Z axes.

[0032] 11. The sample bottle tray is equipped with sample bottle placement holes, which are stepped through holes, and the sample bottles are stored through pneumatic conveying.

[0033] 12. The bottom of the sample bottle tray is equipped with a transport slot, and the transfer bracket is equipped with transport claws. When the sample bottle tray is transferred, the transport claws are inserted into the transport slot, which realizes the safe and reliable transfer of sample bottles. Attached Figure Description

[0034] Figure 1 This is a schematic diagram of the overall structure of the multi-channel friction storage and retrieval system for biomedical samples of the present invention.

[0035] Figure 2 This is a schematic diagram of the sample bottle friction storage and retrieval mechanism in this invention.

[0036] Figure 3 This is a schematic diagram of the sample bottle retrieval unit in the sample bottle friction retrieval mechanism.

[0037] Figure 4 This is a schematic diagram of the sample bottle transport mechanism in the sample bottle storage and retrieval unit.

[0038] Figure 5 This is a schematic diagram of the sample bottle transfer chamber in the sample bottle transport mechanism.

[0039] Figure 6 This is a schematic diagram of the transport pipeline in the sample bottle storage and retrieval unit.

[0040] Figure 7 This is a schematic diagram of the sample bottle storage channel structure in the transportation pipeline.

[0041] Figure 8 This is a schematic diagram of the sample bottle transfer channel structure in the transport pipeline.

[0042] Figure 9 This is a schematic diagram of the high-pressure gas passage in a transport pipeline.

[0043] Figure 10 This is a schematic diagram of the arrangement of the drive mechanism in the sample bottle friction storage mechanism.

[0044] Figure 11 This is a structural diagram of the secondary drive mechanism in the drive mechanism.

[0045] Figure 12 This is a schematic diagram of the sample bottle storage unit in this invention.

[0046] Figure 13 This is a schematic diagram showing the state of the sample bottles inside the storage tube in the sample bottle storage unit.

[0047] Figure 14 This is a schematic diagram of the automatic sealing mechanism in this invention.

[0048] Figure 15 This is a schematic diagram of the upper partition in the automatic sealing mechanism.

[0049] Figure 16 This is a schematic diagram of the structure of the partition plate in the automatic sealing mechanism.

[0050] Figure 17 This is a schematic diagram of the lower partition in the automatic sealing mechanism.

[0051] Figure 18 This is a schematic diagram of the gas delivery mechanism in this invention.

[0052] Figure 19 This is a schematic diagram of the gas storage tank in the gas transmission system.

[0053] Figure 20 This is a schematic diagram of the transition mechanism in this invention.

[0054] Figure 21 This is a schematic diagram of the sample bottle transfer tube in the transition transfer mechanism.

[0055] Figure 22 This is a structural diagram of the transition transfer chamber in the transition transfer mechanism.

[0056] Figure 23 This is a schematic diagram of the transition chamber in the transition transfer mechanism.

[0057] Figure 24 This is a schematic diagram of the sample bottle tray in the transition transfer chamber.

[0058] Figure 25 This is a schematic diagram of the transfer tray in the transition transfer compartment.

[0059] Figure 26 This is a schematic diagram of the gas pipeline structure in the transition and transfer chamber.

[0060] Among them: 1. Temperature and humidity control box, 2. Sample bottle friction storage and retrieval mechanism, 3. Refrigeration control unit, 4. Sample bottle storage unit, 5. Automatic sealing mechanism, 6. Gas delivery mechanism, 7. Transition and transfer mechanism;

[0061] 21. Support; 22. Sample bottle retrieval unit; 23. Sample bottle retrieval drive mechanism;

[0062] 221. Transport pipeline; 222. Sample bottle transport mechanism;

[0063] 2211. Sample bottle transfer compartment; 2212. Support; 2213. Conveyor belt; 2214. Pulley; 2215. Servo motor;

[0064] 22111. Inbound channel installation port; 22112. High-pressure gas pipeline installation port; 22113. Identification device installation port; 22114. Sample bottle transfer channel installation port; 22115. High-pressure gas pipeline installation port; 22116. Sample bottle transfer bin slot; 22117. Identification device installation port; 22118. Outbound channel installation port; 22119. High-pressure gas pipeline installation port;

[0065] 2221. Sample bottle inbound channel; 2222. Inbound high-pressure gas pipeline; 2223. Sample bottle outbound channel; 2224. Outbound high-pressure gas pipeline; 2225. Identification device; 2226. Identification device; 2227. Sample bottle transfer channel; 2228. Transfer high-pressure gas pipeline.

[0066] 22211. Interface, 22212. Pipe, 22213. Capture port;

[0067] 22271. Interface, 22272. Pipe, 22273. Capture port;

[0068] 22221. Interface, 22222. Pipe, 22223. Gas inlet;

[0069] 231. Inbound drive mechanism; 232. Outbound drive mechanism; 233. Third drive mechanism; 234. Fourth drive mechanism;

[0070] 2311. Main drive mechanism; 2312. Secondary drive mechanism; 2313. Telescopic frame; 2314. Grab;

[0071] 41. Sealed box; 42. Storage tube; 43. Sample bottle; 411. Refrigeration medium exchange port;

[0072] 51. Insulation frame; 52. Upper partition; 53. Sealing ball; 54. Middle partition; 55. Lower partition;

[0073] 521. Upper partition through hole; 522. Ventilation groove; 541. Middle partition channel; 551. Lower partition channel hole; 552. Arc-shaped spherical surface;

[0074] 61. Frame; 62. Gas delivery nozzle; 63. Control valve; 64. Gas storage tank; 65. Gas delivery channel; 66. Transmission device;

[0075] 641. Gas storage chamber; 642. Valve interface; 643. Gas supply interface;

[0076] 71. Sample bottle transfer tube; 72. Transition transfer chamber; 73. Rear cover; 74. Front cover; 75. Sample bottle inlet / outlet;

[0077] 711. Interface; 712. Transfer tube body; 713. Sample bottle inlet / outlet;

[0078] 721. Three-dimensional moving platform; 722. Transition chamber; 723. Sample bottle tray; 724. Transfer bracket; 725. Gas delivery pipe;

[0079] 7221. Shelf; 7222. Mounting hole; 7223. Pallet;

[0080] 7231. Sample bottle tray body; 7232. Sample bottle placement hole; 7233. Transfer slot;

[0081] 7241. Handling claw; 7242. Mounting surface; 7243. Air vent; 7244. Positioning platform;

[0082] 7251. Gas inlet, 7252. Gas pipe body, 7253. Gas inlet. Detailed Implementation

[0083] The biomedical sample multi-channel friction access system of the present invention, such as Figure 1 As shown, the system includes, from top to bottom, a sample bottle friction storage and retrieval mechanism 2, a refrigeration control unit 3, a sample bottle storage unit 4, an automatic sealing mechanism 5, a gas supply mechanism 6, and a transition transfer mechanism 7. The entire system is housed within a temperature and humidity control chamber 1, which contains the refrigeration control unit 3. It can also be placed in other environments required for sample storage. The sample bottle friction storage and retrieval mechanism 2, sample bottle storage unit 4, automatic sealing mechanism 5, gas supply mechanism 6, and transition transfer mechanism 7 are connected sequentially from top to bottom, forming a sealed sample bottle storage and retrieval system within the temperature and humidity control chamber 1. The sample bottles 43 containing the samples are stored in the sample bottle storage unit 4. Through the combined action of the sample bottle friction storage and retrieval mechanism 2, automatic sealing mechanism 5, gas supply mechanism 6, and transition transfer mechanism 7, the process of storing, retrieving, and storing the sample bottles is completed.

[0084] The following is a detailed description of the specific structure of each unit.

[0085] 1. Sample bottle friction storage mechanism

[0086] like Figure 2 As shown, the sample bottle friction storage and retrieval mechanism 2 includes a support 21, a sample bottle storage and retrieval unit 22, and a sample bottle storage and retrieval drive mechanism 23. The sample bottle storage and retrieval drive mechanism 23 is mounted on the support 21, and the sample bottle storage and retrieval unit 22 is mounted on the sample bottle storage and retrieval drive mechanism 23.

[0087] like Figure 3 As shown, the sample bottle storage and retrieval unit 22 includes a sample bottle transport mechanism 221 and a transport pipe 222, with the transport pipe 222 connected to the sample bottle transport mechanism 221.

[0088] like Figure 4As shown, the sample bottle transport mechanism 221 includes a support 2212, a sample bottle transfer chamber 2211, a transport belt 2213, pulleys 2214, and a servo motor 2215. Two pulleys 2214 are mounted on the support 2212, one of which is connected to the servo motor 2215 and rotates with it, serving as the drive pulley. The transport belt 2213 is mounted on the two pulleys 2214 and rotates with them. The transport belt 2213 is embedded in the sample bottle transfer chamber slot 22116 within the sample bottle transfer chamber 2211. The transport belt 2213 operates under the drive of the servo motor 2215. When the sample vial 43 containing the biological sample enters the chamber, it is placed on the conveyor belt 2213. A lateral high-pressure gas inlet 22115 (relative to the direction of entry) is set in the sample vial transfer chamber 2211. The high-pressure gas is provided to the sample vial 43 entering the sample vial transfer chamber 2228 to provide lateral thrust, allowing the sample vial 43 to quickly leave the inlet (the sample vial transfer channel installation port 22114). This opens the channel for subsequent sample vials 43 to enter the sample vial transfer chamber 2211. At the same time, it also plays an auxiliary lateral thrust role, correcting the tilting of the sample vials 43 and preventing blockage caused by the tilting of individual sample vials 43.

[0089] like Figure 5 As shown, the sample bottle transfer chamber 2211 is equipped with an inlet channel installation port 22111, a sample bottle transfer channel installation port 22114, a sample bottle transfer chamber slot 22116, an outlet channel installation port 22118, three high-pressure gas pipeline installation ports, and three identification device installation ports. The sample bottle transfer chamber slot 22116 is used to embed the conveyor belt 2213. The conveyor belt 2213 is embedded in the sample bottle transfer chamber slot 22116, forming a closed cavity with the sample transfer chamber 2211. The sample bottle 43 moves along with the conveyor belt 2213. The three high-pressure gas pipeline installation ports are high-pressure gas pipeline installation ports 22112, 22119, and 22115. The three identification device mounting ports are two symmetrical identification device mounting ports 22113 and one identification device mounting port 22117. One identification device 2226 is mounted in each of the two identification device mounting ports 22113, and one identification device 2225 is mounted in the identification device mounting port 22117 (see [link]). Figure 6The identification devices, such as existing QR code readers and RFID card readers, can accurately identify the QR codes or RFID tags on sample bottles 43. Identification devices 2226 are installed in pairs and symmetrically to simultaneously capture information from both the bottle cap and bottom of sample bottles 43, or to prevent situations where only the bottle cap contains information about sample bottles 43, but the bottle caps are not facing the same direction when the sample bottles 43 are stored, thus avoiding missed identification of sample bottle 43 information. Identification device 2225 is designed to capture information from the body of sample bottles 43. By comparing the information from the bottle cap and the body, the accuracy of the sample bottle 43 information is ensured. Simultaneously, sample bottles 43 with abnormal information are removed for further manual verification, ensuring the accuracy of the sample bottle 43 information stored in storage unit 4.

[0090] like Figure 6 As shown, the transport pipeline 222 includes a sample bottle inlet channel 2221, an inlet high-pressure gas pipeline 2222, a sample bottle outlet channel 2223, an outlet high-pressure gas pipeline 2224, multiple sample bottle transfer channels 2227, and a transfer high-pressure gas pipeline 2228. The sample bottle inlet channel 2221 is connected to the inlet channel installation port 22111, the sample bottle transfer channel 2227 is installed at the sample bottle transfer channel installation port 22114, and the sample bottle outlet channel 2223 is installed at the outlet channel installation port 22118. The inlet high-pressure gas pipeline 2222, the outlet high-pressure gas pipeline 2224, and the transfer high-pressure gas pipeline 2228 are respectively connected to high-pressure gas pipeline installation ports 22119, 22112, and 22115. The sample bottle inlet channel 2221 and the inlet high-pressure gas pipeline 2222 are symmetrically arranged on the sample bottle transfer chamber 2211. The sample bottle outgoing channel 2223 and the outgoing high-pressure gas pipeline 2224 are symmetrically installed on the sample bottle transfer chamber 2211. Each high-pressure gas pipeline is equipped with a control valve.

[0091] like Figure 7 As shown, the sample bottle inlet channel 2221 has an interface 22211 and a capture port 22213 at both ends of the pipe 22212. The interface 22211 connects to the inlet channel mounting port 22111, and the capture port 22213 connects to the upper port of the storage tube 42 in the sample storage unit 4. The sample bottle outlet channel 2223 has the same structure as the sample bottle inlet channel 2221, but its capture port is connected to the interface 711 of the sample bottle transfer tube 71 in the transition transfer mechanism 7.

[0092] like Figure 8 As shown, the sample bottle transfer channel 2227 has an interface 22271 and a capture port 22273 respectively set at both ends of the pipe 22272. The interface 22271 is connected to the storage channel installation port 22114, and the capture port 22273 is used to connect to the upper port of the storage tube 42 in the sample storage unit 4.

[0093] like Figure 9 As shown, the inlet high-pressure gas pipeline 2222 has an interface 22221 and a gas inlet 22223 at both ends, with the interface 22221 connecting to the high-pressure gas pipeline installation port 22112. The outlet high-pressure gas pipeline 2224 and the transfer high-pressure gas pipeline 2228 have the same structure as the inlet high-pressure gas pipeline 2222.

[0094] The sample bottle storage and retrieval drive mechanism 23 is equipped with four sets, such as Figure 10 As shown, the system includes an inbound drive mechanism 231, an outbound drive mechanism 232, a transfer drive mechanism 233, and a fourth drive mechanism 234. The inbound drive mechanism 231 drives the sample bottle inbound channel 2221, and the outbound drive mechanism 232 drives the sample bottle outbound channel 2223. The transfer drive mechanism 233 and the fourth drive mechanism 234 drive the sample bottle transfer channel 2227. Since there are multiple sample bottle transfer channels 2227 located on both sides, the fourth drive mechanism 234 handles the driving of the other sample bottle transfer channels 2227 to improve efficiency. The four drive mechanisms can perform tasks according to the principle of proximity (not exclusively assigned to any one channel, thus improving efficiency), driving the corresponding channel to the predetermined position to complete tasks such as outbound, inbound, and return. The structure of each drive mechanism is as follows... Figure 11 As shown, taking the inbound drive mechanism 231 as an example, its structure includes a main drive mechanism 2311 and a secondary drive mechanism 2312. The secondary drive mechanism 2312 is connected to the power output end of the main drive mechanism 2311. The main drive mechanism 2311 adopts a screw-nut pair moving mechanism. The screw is mounted on the bracket 21 and connected to the drive motor, and the nut is connected to the screw. The secondary drive mechanism 2312 adopts an electric telescopic gripper, which is existing technology. It includes an electric telescopic frame 2313 and a gripper 2314. The electric telescopic frame 2313 is connected to the nut in the main drive mechanism, and the gripper 2314 is connected to the end of the electric telescopic frame 2313. Each channel (sample bottle inbound channel 2221, sample bottle outbound channel 2223, sample bottle transfer channel 2227) is gripped by the gripper 2314 of the corresponding drive mechanism, and is driven to dock with relevant components through the cooperation of the main drive mechanism 2311 and the secondary drive mechanism 2312.

[0095] The operation process of the above-mentioned sample bottle friction storage and retrieval mechanism 2 is as follows.

[0096] Sample bottles 43 enter the sample bottle transfer chamber 2211 through any of the sample bottle transfer channels 2227 or the sample bottle outgoing channel 2223. High-pressure gas in the transfer high-pressure gas channel 2228 propels the sample bottle 43 quickly away from the inlet position and onto the conveyor belt 2213. The sample bottle 43 then moves within the sample bottle transfer chamber 2211 along with the conveyor belt 2213. Simultaneously, the high-pressure gas entering the sample bottle transfer chamber 2211 via the transfer high-pressure gas channel 2228 also provides auxiliary lateral thrust, correcting any tilting of the sample bottles 43 and preventing blockages caused by the tilting of individual sample bottles 43.

[0097] When sample bottle 43 needs to be retrieved (removed from storage tube 42), transfer drive mechanism 233 drives the lower port of a sample bottle transfer channel 2227 to connect with the upper port of the storage tube 42 corresponding to the retrieved sample bottle. Retrieval drive mechanism 232 drives sample bottle retrieval channel 2223 to connect with sample bottle transfer tube 71 in transition transfer mechanism 7. Under the action of automatic sealing mechanism 5 and gas delivery mechanism 6, sample bottle 43 enters sample bottle transfer channel 2227 from storage tube 42, then enters sample bottle transfer chamber 2211 from sample bottle transfer channel 2227, and is placed on conveyor belt 2213.

[0098] As sample bottle 43 moves along conveyor belt 2213 in sample bottle transfer chamber 2211, its information is captured successively by two identification devices 2226 and 2225. After data analysis and processing, if it is determined that the sample bottle 43 is the one to be retrieved, when sample bottle 43 reaches the outlet channel installation port 22118 and high-pressure gas channel installation port 22112 (the outlet channel installation port 22118 and high-pressure gas channel installation port 22112 are symmetrical with the sample bottle transfer chamber 2211; the sample bottle outlet channel 2223 is connected to the outlet channel installation port 22118, and the high-pressure gas pipeline 2224 is connected to the high-pressure gas channel installation port 22112), the control valve of the high-pressure gas pipeline 2224 is activated. High-pressure gas blows sample bottle 43 into the sample bottle outlet channel 2223 through the high-pressure gas channel installation port 22112, and then enters the transition transfer mechanism 7 through the sample bottle transfer pipe 71, where the outbound process is completed.

[0099] If it is determined that the sample bottle 43 is not the sample bottle 43 to be taken, the sample bottle 43 continues to move forward on the conveyor belt 2213. When it reaches the installation port 22111 of the storage channel, the control valve on the storage high-pressure gas pipeline 2222 opens, blowing the sample bottle 43 into the sample bottle storage channel 2221. The sample bottle 43 then re-enters the storage pipe 42, completing the return process.

[0100] When sample bottle 43 needs to be stored in sample bottle storage unit 4 (during storage), the sample bottle 43 is first placed into sample bottle transfer chamber 2211 according to the operation process of transition transfer mechanism 7. As sample bottle 43 moves in sample bottle transfer chamber 2211 along conveyor belt 2213, its information is captured by two identification devices 2226 and 2225. After data analysis and processing, if the information of sample bottle 43 is determined to be incorrect, when sample bottle 43 reaches the outlet channel installation port 22118 and high-pressure gas channel installation port 22112 (the outlet channel installation port 22118 and high-pressure gas channel installation port 22112 are symmetrical with sample bottle transfer chamber 2211), the sample bottle exits... Storage channel 2223 is connected to the outgoing channel installation port 22118, and high-pressure gas pipeline 2224 is connected to the high-pressure gas channel installation port 22112. When the control valve of high-pressure gas pipeline 2224 is activated, high-pressure gas blows the sample bottle 43 through the high-pressure gas channel installation port 22112 into the sample bottle outgoing channel 2223, then through the sample bottle transfer pipe 71 into the transition transfer mechanism 7, where the outgoing process is completed (information mismatch, returned, cannot be stored). If it is determined that the sample bottle 43 is a sample bottle to be stored, the sample bottle 43 continues to move forward on the conveyor belt 2213. When it reaches the incoming channel installation port 22111, the control valve on the incoming high-pressure gas pipeline 2222 opens, blowing the sample bottle 43 into the sample bottle incoming channel 2221. The sample bottle 43 then re-enters the storage pipe 42, completing the incoming process.

[0101] 2. Sample bottle storage unit

[0102] like Figure 12 As shown, the sample bottle storage unit 4 adopts a bundled tube structure, including a sealed box 41. A refrigerant exchange port 411 is provided on the side wall of the sealed box 41. Storage tubes 42 are vertically distributed inside the sealed box 41. The storage tubes 42 are fixed by tube plates at both ends of the sealed box 41, and both ends of the storage tubes 42 are open. The storage tubes 42 are used to store sample bottles 43, such as... Figure 13 As shown. The functions of the sealed box 41 are: firstly, to provide the sample storage unit with an independent and stable temperature and humidity environment, the temperature of which can be below -25℃; secondly, to isolate the sample storage unit 4 from other institutions or units, so that it has its own exclusive temperature and humidity environment.

[0103] 3. Automatic sealing mechanism

[0104] like Figure 14 As shown, the automatic sealing mechanism 5 includes a heat insulation frame 51 and an upper partition 52, a middle partition 54, a sealing ball 53, and a lower partition 55 connected together from top to bottom.

[0105] like Figure 15As shown, the upper partition 52 has through holes 521 distributed on it, and multiple ventilation grooves 522 are engraved on the inner wall of the through holes. The diameter of the through holes 521 is smaller than the diameter of the sealing ball 53, which serves to restrict the sealing ball 53. The outer diameter of the ventilation groove 522 is approximately the same as the diameter of the through hole 541, which is the channel for high-pressure gas to enter the storage pipe 42.

[0106] like Figure 16 As shown, the partition plate 54 has through holes 541 distributed on it, and a sealing ball 53 is installed inside the through hole 541. The diameter of the through hole 541 is larger than the diameter of the sealing ball 53, which is the suspension area of ​​the sealing ball and also the channel through which high-pressure gas flows.

[0107] like Figure 17 As shown, the lower partition plate 55 has through holes 551 distributed on it, and it is rounded and chamfered to form an arc-shaped spherical surface 552. The diameter of the arc-shaped spherical surface 552 is not greater than the diameter of the sealing ball 53. When the sealing ball 53 loses the external pressure, it falls into the spherical arc surface 552 by its own weight, sealing the through holes 551 of the lower partition plate.

[0108] The diameter of the sealing ball 53 is smaller than the inner diameter of the through hole 551 and larger than the through holes 521 and 551 of the upper partition and the lower partition. The distribution of the through holes 521, 541 and 551 of the upper partition is consistent with the distribution of the storage tubes in the sample bottle storage unit (coaxial and corresponding one-to-one).

[0109] 4. Gas transmission mechanism

[0110] like Figure 18 , 19 As shown, the gas delivery mechanism 6 includes a frame 61, a gas delivery nozzle 62, a control valve 63, a gas storage chamber 64, a gas delivery channel 65, and a transmission device 66. The gas storage chamber 641 is equipped with multiple valve ports 642 and one gas delivery port 643. The transmission device 66 is mounted on the frame 61 and employs a screw-nut pair moving mechanism. The screw is mounted on the frame 61, and the nut is connected to the screw. The gas storage chamber 64 is connected to the nut. The gas delivery nozzle 62 is connected to the valve ports 642 of the gas storage chamber 64 via the control valve 63. The gas delivery channel 65 is connected to the gas delivery port 643 of the gas storage chamber 64, and the gas delivery channel 65 delivers high-pressure gas into the gas storage chamber 64. The transmission device 66 drives the gas storage chamber 64 to move, causing the gas delivery nozzle 62 to move to a predetermined position.

[0111] The operation process of the gas delivery mechanism 6 and the automatic sealing mechanism 5 is as follows:

[0112] Under the control of the transmission mechanism 66, the gas delivery nozzle 62 aligns with a row of lower partition through holes 551 on the corresponding lower partition 55. High-pressure gas enters one or more corresponding lower partition through holes 551 on the lower partition 55 through the gas delivery nozzle 62. Under the action of the high-pressure gas, the sealing ball 53 is suspended in the corresponding middle channel 541 of the middle partition 54, and the sealing effect fails. The high-pressure gas then enters one or more storage tubes 42 through the corresponding venting groove 522 on the upper partition 52, pushing the sample bottle 43 in the storage tube 42 upward. When the gas pressure is released, the sealing ball 53 falls into the arc-shaped spherical surface 552 of the lower partition 55 by its own gravity, achieving a self-sealing effect. The sealing ball 53 must have a sufficiently high density so that it cannot suspend without the action of high-pressure gas flow.

[0113] 5. Transitional / Relocation Agency

[0114] like Figure 20 As shown, the transition transfer mechanism 7 includes a sample bottle transfer tube 71 and a transition transfer chamber 72. The sample bottle transfer tube 71 is connected to the top of the transition transfer chamber 72. A rear cover plate 73 is provided at the rear of the transition transfer chamber 72, and an openable front cover plate 74 is provided at the front. A sample bottle storage port 75 is provided on the front cover plate 74.

[0115] like Figure 21 As shown, the sample bottle transfer tube 71 has interfaces 711 and sample bottle inlets / outlets 713 at both ends of the transfer tube body 712. The transfer tube body 712 enters the transition chamber 722 through the mounting hole 7222. The sample bottle transfer tube 71 connects to the outgoing sample bottle transfer channel 2223 or the sample bottle transfer channel 2227 in the sample bottle friction storage and retrieval mechanism 2. The sample bottle 43 enters and exits the transition transfer chamber 72 through the sample bottle inlet / outlet 713. The sample bottle 43 is transferred between the transition transfer mechanism 7 and the sample bottle friction storage and retrieval mechanism 2 through the sample bottle transfer tube 71.

[0116] like Figure 22 As shown, the transition transfer chamber 72 is internally equipped with a three-dimensional moving platform 721, a transition chamber 722, a sample bottle tray 723, a transfer bracket 724, and a gas supply pipe 725. The three-dimensional moving platform 721 is existing technology and is installed inside the transition chamber 722. The transfer bracket 724 is installed at the power output end of the three-dimensional moving platform 721 and is driven by the three-dimensional moving platform 721 to perform three-dimensional movement (up / down, left / right, and forward / backward) to reach the desired position. The sample bottle tray 723 is placed on the pallet 7223 within the transition chamber 722. Figure 23As shown, the transition chamber 722 includes a frame 7221 and a tray 7223. The upper end of the frame 7221 has mounting holes 7222 for the sample bottle transfer tube 71, which connect to the sample bottle transfer tube 71. The trays 7223 are horizontally arranged and fixed within the frame 7221 for temporarily storing the sample bottle trays 723. A gas delivery pipe 725 is located on the side wall of the transition chamber 722 (or alternatively on the rear cover 73). One end of the gas delivery pipe 725 is positioned directly below the sample bottle inlet / outlet 713 of the sample bottle transfer tube 71 within the transition chamber 722. The distance between the gas delivery pipe 725 and the sample bottle transfer tube 71 is the same as the height of the sample bottle tray 723. The other end of the gas delivery pipe 725 is connected to a gas delivery nozzle 62 in the gas delivery mechanism 6.

[0117] like Figure 24 As shown, the sample bottle tray 723 has a sample bottle placement hole 7232 on the sample bottle tray body 7231, and a transport groove 7233 is provided at the bottom of the sample bottle tray body 7231. The sample bottle placement hole 7232 is a stepped through hole with a larger diameter at the top and a smaller diameter at the bottom. The sample bottle 43 is placed at the top, and the bottom is used to support the sample bottle 43 and allow gas to enter, blowing the sample bottle 43 out.

[0118] like Figure 25 As shown, the transfer bracket 724 includes a transport claw 7241, a mounting surface 7242, and a positioning stage 7244. One side of the transport claw 7241 is the positioning stage 7244, used to limit the placement position of the sample bottle tray 7231. The lower bottom surface of the positioning stage 7244 is the mounting surface 7242, used to connect with the three-dimensional moving platform 721. The transport claw 7241 is provided with a vent hole 7243, which corresponds to the sample bottle placement hole 7232 on the sample bottle tray 7231. When the sample bottle tray 723 is placed on the transfer bracket 724, the transport claw 7241 will block the sample bottle placement hole 7232 on the sample bottle tray 7231 above it. The purpose of providing the vent hole 7243 is to allow gas to enter the sample bottle placement hole 7232 through the vent hole 7243. The transport claw 7241 is inserted into the transport slot 7233 at the bottom of the sample bottle tray 723, lifting the sample bottle tray 7231 and moving it in three dimensions within the transition chamber 722 along with the three-dimensional moving platform 721.

[0119] like Figure 26 As shown, the gas supply pipe 725 has gas inlets 7251 and gas inlets 7253 at both ends of the gas supply pipe body 7252. The gas supply pipe body 7252 is mounted on the rear cover plate 73, and the gas inlets 7251 are located directly below the sample bottle inlet / outlet 713. The distance between the gas inlet 7251 and the sample bottle inlet / outlet 713 is the same as the height of the sample bottle tray 723 (the height of the transport claw 7241 is the same as the height of the transport slot 7233). The gas inlet 7253 is connected to a gas nozzle 62 in the gas supply mechanism 6.

[0120] The operation process of the aforementioned transition mechanism 7 is as follows.

[0121] Sample bottles 43 are placed in sample bottle placement holes 7232 on sample bottle tray 723. Sample bottle tray 723 enters and exits the transition mechanism 7 through sample bottle storage port 75, and the three-dimensional moving platform 721 realizes the transportation of sample bottle tray 723 between sample bottle pick-up and drop port 75 and shelf 7221.

[0122] When sample bottles 43 enter the outbound process, they enter the sample bottle transfer tube 71 through the sample bottle outbound channel 2223. Sample bottles 43 continuously exit from the sample bottle inlet / outlet 713. The sample bottle tray 723, driven by the three-dimensional moving platform 721, continuously moves, allowing empty sample bottle placement holes 7232 to receive the sample bottles 43 exiting from the inlet / outlet 713, placing each sample bottle 43 into the placement hole 7232. When the sample bottle tray 723 is full of sample bottles 43, or when the number of sample bottles 43 retrieved meets the requirement (the sample bottle tray 723 is not yet full), the three-dimensional moving platform 721 temporarily places the sample bottle tray 723 onto the pallet 7223, or moves it out through the sample bottle storage port 75 via the transition mechanism 7, completing the outbound task.

[0123] When sample bottles 43 need to be stored in sample bottle storage unit 4 (during storage), sample bottles 43 are first placed in sample bottle placement holes 7232. Sample bottle trays 723 are placed into transition transfer chambers 72 through sample bottle storage openings 75 and placed on pallets 7223. The three-dimensional moving platform 721 drives the transport claws 7241 into the transport slots 7233 at the bottom of the sample bottle trays 723. To improve the speed at which sample bottle trays 723 enter the transition transfer mechanism 7, if too many sample bottle trays 723 are stored at once, they can be placed on pallets 7223 first. After all the sample bottle trays 723 to be stored have entered the transition transfer mechanism 7, the three-dimensional moving platform 721 drives the sample bottle trays 723 to move to a predetermined position (sample bottle inlet / outlet 713). The second access drive mechanism 232 drives the sample bottle transfer channel 2227 (or the third access drive mechanism drives the sample bottle transfer channel 2227) to connect its gripping port 22273 with the interface 711 of the sample bottle transfer tube 71 in the transition transfer mechanism 7. At this time, the gas inlet 7251 of the gas supply pipe 725, the sample bottle placement hole 7232 on the sample bottle tray 723 where the corresponding sample bottle 43 is placed, and the sample bottle inlet / outlet 713 of the sample bottle transfer tube 71 are aligned. The control valve 63 controlling the gas supply nozzle 62 connected to the gas supply pipe 725 is opened, and high-pressure gas is blown through the gas supply interface 7253 of the gas supply pipe 725 to the sample bottle placement hole 7232, blowing the sample bottle 43 in the sample bottle placement hole 7232 into the sample bottle transfer tube 71, and then into the sample bottle transfer chamber 2211 through the sample bottle transfer channel 2227. If the sample bottle placement hole 7232 is directly below the transport claw 7241, the gas blown from the gas inlet 7253 of the gas supply pipe 725 enters the sample bottle placement hole 7232 directly or through the gas guide hole 7243, blowing the sample bottle out of the sample bottle placement hole 7232 and into the sample bottle transfer channel 71. In this way, the sample bottles 43 are transferred one by one through the sample bottle transfer channel 71 into the sample bottle transfer channel 2227, and then into the sample bottle transfer chamber 2211. Finally, the sample bottles are stored according to the storage process described in the sample bottle friction storage and retrieval mechanism 2.

[0124] The operation process of the entire biomedical sample multi-channel triboelectric storage system of the present invention is as follows.

[0125] First, a closed channel for sample bottle transfer is constructed. Relying on the relevant sample bottle storage and retrieval drive mechanism 23, the corresponding pipes, interfaces, and nozzles are quickly connected to form a closed channel. For example, the closed channel for outbound samples is as follows: the outbound drive mechanism 232 drives the sample bottle outbound channel 2223 to connect with the sample bottle transfer pipe 71 in the transition transfer mechanism 7; the transfer drive mechanism 233 drives the gripping port 22273 of the sample bottle transfer channel 2227 to connect with the upper port of the storage pipe 42 corresponding to the outbound sample bottle; and the gas delivery nozzle 62 is connected with the corresponding lower port of the storage pipe 42. Then, based on the relevant identification device, the sample bottle 43 is accurately captured, achieving accurate outbound, return, and inbound processing of the sample bottle 43.

[0126] When a specific sample bottle 43 is retrieved (outbound), the transfer drive mechanism 233 drives the gripping port 22273 of a sample bottle transfer channel 2227 to align with the upper port of the storage tube 42 corresponding to the sample bottle being retrieved. The outbound drive mechanism 232 then drives the sample bottle outbound channel 2223 to connect with the sample bottle transfer tube 71 in the transition transfer mechanism 7. Under the control of the transmission mechanism 66, the gas delivery nozzle 62 aligns with a row of lower partition through holes 551 in the lower partition 55 of the automatic sealing mechanism 5 corresponding to the lower port of the storage tube 42 where the sample bottle 43 is located, and opens one or more control valves 63 to deliver high-pressure gas to the corresponding storage tube 42, sending the sample bottle 43 into the sample bottle transfer channel 2227. The sample bottle then enters the sample bottle transfer chamber 2221 through the sample bottle transfer channel 2227 and is placed on the conveyor belt 2213. The high-pressure gas enters the sample bottle transfer chamber 2221 through the high-pressure gas transfer pipe 2228, propelling the sample bottle 43 along the conveyor belt. The sample bottle 43 moves laterally along with sample bottle 2213. When it passes the identification area of ​​identification device 2226, the information on the cap and bottom of the sample bottle 43 is captured. When it reaches the identification area of ​​identification device 2225, the information on the body of the sample bottle 43 is captured. The two captured information of sample bottle 43 are compared and judged. If the sample bottle 43 is the sample bottle to be retrieved, the high-pressure gas pipeline 2224 is sprayed, and the sample bottle 43 leaves the sample bottle transfer chamber 2211 from the sample bottle exit channel 2223, and then enters the transition transfer mechanism 7 through the sample bottle transfer pipe 71, where the exit process is completed. If the sample bottle 43 is not the sample bottle to be retrieved, the sample bottle 43 continues to move forward. When it reaches the working area of ​​the high-pressure gas pipeline 2222, the high-pressure gas pipeline 2222 is sprayed, and the sample bottle 43 enters the return process from the sample bottle entry channel 2221.

[0127] When it is necessary to store sample bottle 43 into sample bottle storage unit 4 (during warehousing), the sample bottle 43 is first placed into sample bottle transfer chamber 2211 in sample bottle friction storage and retrieval mechanism 2 according to the operation process of transition transfer mechanism 7, and then the warehousing process is carried out according to the warehousing process described in sample bottle friction storage and retrieval mechanism 2.

[0128] Specific embodiments are given below.

[0129] I. Sample Bottle Storage Unit 4

[0130] The temperature and humidity control box 1 is designed to be 1200mm long, 1200mm wide, and 1800mm high, with a 50mm thick insulation layer, and is equipped with a temperature and humidity control system.

[0131] The sample bottle storage unit 4 is designed to be 1000mm long, 800mm wide, and 1000mm high. The storage tube 42 is made of acrylic round tube with an inner diameter of Φ20mm, an outer diameter of Φ24mm, and a length of 900mm. The upper and lower tube plates are 1000mm long, 800mm wide, and 10mm thick, made of acrylic. Each tube has 33 stepped holes evenly distributed along its long side and 25 stepped holes evenly distributed along its short side, for a total of 825 stepped holes. The hole spacing is 30mm. The large hole of the stepped hole is Φ24mm, and the small hole is Φ20mm. First, the storage tubes are inserted one by one into the Φ24mm holes of the lower tube plate, then the storage tubes are inserted one by one into the Φ24mm holes of the upper tube plate and secured. The storage tube bundle is then complete. An insulation layer with a thickness of 50mm is installed around the longitudinal perimeter of the storage tube bundle. Four Φ100 cooling medium exchange holes are left on two symmetrical sides, with a spacing of 400mm between the holes on the same side, for installing cooling medium exchange ports. The sample bottle storage unit is now complete.

[0132] II. Sample Bottle Friction Storage Mechanism

[0133] 1. Sample bottle transfer chamber fabrication

[0134] 1) Make a rectangular trough with a wall thickness of 5mm, a length of 360mm, a width of 50mm, and a height of 30mm. On the wide side, cut a 300*30mm groove. This groove is filled by a conveyor belt to form a complete cavity.

[0135] 2) Drill a Φ10 hole at the corresponding position for installing the corresponding channel. Drill a 30*20mm groove on the other side for installing the identification device.

[0136] 2. Sample bottle transport mechanism manufacturing

[0137] 1) Make two Φ60mm, 40mm long rotating drums for installing the conveyor belt, and machine a Φ30mm center hole.

[0138] 2) The central shaft is designed to be Φ30mm.

[0139] 3) Design two supports. The supports are designed with a bottom width of 60mm, a top width of 30mm, a height of 70mm, and a wall thickness of 10mm. A Φ30mm center hole is opened 50mm from the bottom for mounting the rotating cylinder. Two Φ10mm holes are opened on the bottom for fixing the installation.

[0140] 4) Select a 5mm thick, 30mm wide rubber belt for the conveyor belt.

[0141] 5) Fix the two supports 300mm apart, install the conveyor belt correctly onto the drum, and install a servo motor on one of the central shafts.

[0142] The sample bottle transport mechanism has been completed.

[0143] III. Sample Bottle Retrieval Unit Construction

[0144] 1. The conveyor belt is embedded in the slot of the sample bottle transfer chamber, forming an integral part with the sample bottle transport mechanism.

[0145] 2. Install the sample bottle inlet channel, sample bottle outlet channel, sample bottle transfer channel, 3 high-pressure gas pipelines, and 3 sets of identification devices at the corresponding ports.

[0146] IV. Automatic sealing mechanism 5

[0147] 1) Make an insulation frame with dimensions of 1000*800*35mm and an insulation layer thickness of 50mm.

[0148] 2) The upper partition is 1000mm long, 800mm wide and 10mm thick, made of engineering plastic, with 825 ventilation slots and through holes evenly distributed, corresponding one-to-one with the 825 holes of the storage unit tube bundle. The center distance of the outer hole is 140mm from the edge line, the inner diameter of the through hole is Φ10mm, the ventilation slot size is 15*2mm, and there are 6 evenly distributed ventilation slots.

[0149] 3) The pneumatic channel is 1000mm long, 800mm wide, and 15mm thick. It is made of engineering plastic and has 825 ventilation slots and holes that correspond one-to-one with the 825 holes on the upper partition. The center of the outer hole is 140mm from the edge line and the diameter of the hole is Φ15mm.

[0150] 4) The lower partition is 1000mm long, 800mm wide, and 10mm thick. It is made of stainless steel and has 825 ventilation slots and holes that correspond one-to-one with the 825 holes in the upper and middle partitions. The center of the outer hole is 140mm from the edge line, the diameter of the hole is Φ10mm, and the rounded chamfer is R2.

[0151] 5) The diameter of the gas sealing ball is Φ12mm.

[0152] 6. Install the lower partition, sealing ball, middle partition, and upper partition into the heat insulation frame in sequence, and connect them together with fasteners. The gas sealing mechanism is now assembled.

[0153] The refrigeration control unit, gas delivery mechanism, gas sealing mechanism, sample bottle storage unit, transition transfer mechanism, and sample bottle retrieval mechanism are assembled into one unit through auxiliary connectors and placed in the temperature control mechanism. Then, the relevant actuators are installed separately, and a multi-channel friction-type sample bottle retrieval system is assembled.

[0154] V. Transitional Transfer Agency 7

[0155] 1) Front cover, designed to be 1000*1200*10mm, with a 300*100mm opening in the center.

[0156] 2) Transition compartment, designed to be 1000*1200*300mm, with a Φ22mm hole centered at the top.

[0157] 3) The rear cover plate is designed to be 1000*1200*10mm, with a Φ12mm hole centered 30mm from the bottom.

[0158] 4) Pallet, designed to be 200*140*10mm.

[0159] 5) Tray, designed to be 240*140*40mm, with 45 sample bottle placement holes evenly distributed. The placement holes are stepped holes, with the upper part having a dimension of Φ=20mm and a depth of 30mm, and the lower part having a dimension of Φ10mm and a depth of 10mm. On the other side, there are two symmetrical 30*5mm slots with a spacing of 140mm.

[0160] 6) The transfer bracket is designed in a 200*150mm "U" shape. At the bottom of the "U" shape, a 200*10*20mm boss is created to restrict the tray's position. The claws are 140mm long, 30mm wide, and 5mm thick, with a 140mm distance between the two claws (corresponding to the tray's groove). Five Φ10mm holes are drilled on each claw, their positions corresponding to the tray's horizontal holes. A 30*50*20mm boss is created on the bottom edge of the "U" shape for connection to the 3D moving platform.

[0161] 7) Install the pallet and the three-dimensional moving platform onto the transition chamber in sequence, connect the transfer bracket to the three-dimensional moving platform, and connect the front cover plate and the rear cover plate to the transition chamber. The transition transfer mechanism is now complete.

Claims

1. A multi-channel triboelectric storage system for biomedical samples, characterized in that, It includes a sample bottle friction storage and retrieval mechanism, a sample bottle storage unit, an automatic sealing mechanism, a gas conveying mechanism, and a transition transfer mechanism arranged from top to bottom. The sample bottle friction storage and retrieval mechanism includes a support, a sample bottle storage and retrieval unit, and a sample bottle storage and retrieval drive mechanism, with the drive mechanism mounted on the support. The sample bottle storage and retrieval unit includes a sample bottle transport mechanism and a transport pipeline, with the pipeline connected to the transport mechanism. The sample bottle transport mechanism includes a support, a sample bottle transfer chamber, a transport belt, pulleys, and a servo motor. Two pulleys are mounted on the support, one of which is connected to the servo motor. The transport belt is mounted on the two pulleys and embedded in the sample bottle transfer chamber. The transport pipeline includes a sample bottle inlet channel, an inlet high-pressure gas pipeline, a sample bottle outlet channel, an outlet high-pressure gas pipeline, a sample bottle transfer channel, and a transfer high-pressure gas pipeline. Each high-pressure gas pipeline is equipped with a control valve. At least one sample bottle storage and retrieval drive mechanism is provided, driving the sample bottle transfer channel or the sample bottle inlet channel to connect with the sample bottle storage unit, or driving the sample bottle outlet channel to connect with the transition transfer mechanism. The sample bottle inlet channel and the inlet high-pressure gas pipeline are symmetrically arranged on the sample bottle transfer chamber; the sample bottle outlet channel and the outlet high-pressure gas pipeline are symmetrically installed on the sample bottle transfer chamber.

2. The multi-channel triboelectric access system for biomedical samples according to claim 1, characterized in that, The sample bottle transfer chamber is equipped with an identification device. There are three identification devices, two of which are arranged symmetrically.

3. The multi-channel triboelectric access system for biomedical samples according to claim 1, characterized in that, The access drive mechanism includes a main drive mechanism and a secondary drive mechanism, with the secondary drive mechanism connected to the power output end of the main drive mechanism. The main drive mechanism employs a lead screw and nut pair moving mechanism. The secondary drive mechanism employs an electric telescopic gripper, including an electric telescopic frame and a gripper. The electric telescopic frame is connected to the power output end of the main drive mechanism, and the gripper is connected to the end of the electric telescopic frame.

4. The multi-channel triboelectric access system for biomedical samples according to claim 1, characterized in that, The sample bottle storage unit adopts a bundled tube structure, including a sealed box. A refrigerant exchange port is provided on the side wall of the sealed box. Storage tubes are vertically distributed inside the sealed box. The storage tubes are fixed by tube plates at the upper and lower ends of the sealed box. Both the upper and lower ends of the storage tubes are open.

5. The multi-channel triboelectric access system for biomedical samples according to claim 1, characterized in that, The automatic sealing mechanism includes a heat insulation frame and an upper partition, a middle partition, and a lower partition connected together from top to bottom within the heat insulation frame. The upper partition has upper through holes with ventilation grooves engraved on their inner walls. The middle partition has circular through holes with a sealing ball inside each hole; the diameter of the circular through hole is larger than the diameter of the sealing ball. The lower partition has lower through holes. The diameter of the sealing ball is smaller than the inner diameter of the circular through hole but larger than the inner diameters of the upper and lower through holes. The distribution of the upper, circular, and lower through holes is consistent with the distribution of the storage tubes in the sample bottle storage unit.

6. The multi-channel triboelectric access system for biomedical samples according to claim 1, characterized in that, The gas delivery mechanism includes a frame, a gas delivery nozzle, a control valve, a gas storage chamber, a gas delivery channel, and a transmission device. The transmission device is mounted on the frame, the gas storage chamber is connected to the transmission device, the gas delivery nozzle is connected to the gas storage chamber through the control valve, and the gas delivery channel is connected to the gas storage chamber.

7. The multi-channel triboelectric access system for biomedical samples according to claim 1, characterized in that, The transition transfer mechanism includes a sample bottle transfer tube, a sample bottle inlet / outlet, a transition transfer chamber, and a gas delivery tube. The sample bottle transfer tube is connected above the transition transfer chamber. The transition transfer chamber contains a three-dimensional moving platform, a transition chamber, a sample bottle tray, and a transfer bracket. The transfer bracket is installed at the power output end of the three-dimensional moving platform. The transition chamber includes a frame and a tray. The tray is fixed in the frame, and the sample bottle tray is placed on the tray. The gas delivery tube is located on the side wall of the transition chamber. One end of the gas delivery tube inside the transition chamber is opposite to the port of the sample bottle transfer tube, and the other end of the gas delivery tube is connected to the gas delivery mechanism.

8. The multi-channel triboelectric access system for biomedical samples according to claim 7, characterized in that, The sample bottle tray has sample bottle placement holes on the sample bottle tray body and a transport groove at the bottom of the sample bottle tray body; the sample bottle placement holes are stepped through holes with a larger diameter at the top and a smaller diameter at the bottom.

9. The multi-channel triboelectric access system for biomedical samples according to claim 7, characterized in that, The transfer bracket is equipped with a transport claw, and the transport claw is equipped with an air guide hole.

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