An inducing device for promoting the precipitation of bezoar crystals

Abstract

The present invention relates to an inducing device for promoting the precipitation of bezoar crystals and a method for using the same. The inducing device comprises two half-covers arranged opposite each other, wherein the outer surfaces of the half-covers are provided with a plurality of grooves evenly arranged along the circumference of the half-covers, the plurality of grooves dividing the outer surfaces of the half-covers into a plurality of arcuate surfaces evenly arranged along the circumference, and the arcuate surfaces and the bottoms of the grooves are both provided with a plurality of partition holes arranged along the extension direction of the arcuate surfaces and communicating with the inner cavities of the half-covers. In the present invention, by providing the grooves, the arcuate surfaces and the grooves are staggered in the circumference of the half-covers, thereby making the outer surfaces of the half-covers uneven, and the partition holes are provided on the arcuate surfaces and the grooves, thereby increasing the contact area between bile and the half-covers and facilitating the precipitation of bezoar crystals. The provision of a core cotton ball slows down the flow rate of bile entering the bed, facilitating the deposition of bezoar crystals on the bed.

Description

Technical Field

[0001] The invention belongs to the field of bezoar cultivation auxiliary equipment, and particularly relates to an inducing device for promoting bezoar crystal precipitation and a use method thereof. Background Art

[0002] Bezoar, the dried gallstones found in the gallbladder, bile duct, or hepatic duct of cattle, is a traditional and precious animal medicinal material in my country and a component of numerous prescriptions. my country's production of bezoar is low, while demand for its use in medicine is high, resulting in a long-standing shortage. To address this shortage, Chinese scientists, drawing on the formation mechanism of natural bezoar, have successfully developed a surgical technique for cultivating bezoar within the gallbladders of living cattle and successfully cultivated them. This live bezoar cultivation technique involves implanting a specially prepared bezoar bed within the gallbladder of a living cattle through veterinary surgery. The cattle are then reared for a period of time and then either surgically or slaughtered to produce the cultivated bezoar. The bed serves as a carrier for the precipitation of bezoar crystals and is crucial to the yield and quality of bezoar.

[0003] The Chinese invention patent application number CN202221215149.8 discloses a detachable bed, but the contact area between the bile and the bed is small, and there is no buffering and flow reduction device inside. Bezoar crystals are not easy to deposit on the surface of the bed, the bezoar is poorly formed, and the output is not high. Summary of the Invention

[0004] In response to the deficiencies of the prior art, the present invention provides an inducing device for promoting the precipitation of bezoar crystals and a method for using the device, which reduces the contact area between bile and the bed, adds a core cotton ball inside the bed for buffering and reducing flow, enhances the deposition of bezoar crystals on the bed surface, promotes bezoar formation, and increases bezoar yield.

[0005] The present invention is achieved through the following technical solution: an inducing device for promoting the precipitation of bezoar crystals, including a bed body, wherein the bed body includes two semi-ellipsoidal half-cover bodies that are arranged opposite to each other and whose opposite surfaces are detachably connected. A plurality of grooves extending inward and evenly arranged along the circumference of the half-cover bodies are provided on the outer surface of the half-cover bodies. The plurality of grooves divide the outer surface of the half-cover bodies into a plurality of arc surfaces evenly arranged along the circumference. The grooves and the arc surfaces are arranged in an alternating manner. The arc surfaces and the bottom of the grooves are both provided with a plurality of partition holes arranged along the extension direction of the arc surfaces and connected to the inner cavity of the half-cover bodies.

[0006] The present invention arranges the grooves so that the arc surface and the grooves are arranged alternately in the circumferential direction of the half cover, so that the inner and outer surfaces of the half cover are uneven. The uneven inner surface causes part of the bile to flow on the groove walls when bile flows from the inside to the outside, thereby increasing the contact area between the bile and the half cover, facilitating the precipitation of bezoar crystals. At the same time, the uneven outer surface makes it difficult for the bed to twist when it is placed in the body of the cattle gallbladder.

[0007] Preferably, both ends of the groove extend to the open opening and the contracted opening of the half cover respectively, and the bottom of the groove is a plane.

[0008] This preferred solution increases the length of the groove wall by extending the groove; increases the width of the groove by setting the plane, further increases the contact area between the bile and the half cover, and further promotes the precipitation of bezoar crystals.

[0009] Preferably, the two partition holes are separated by a partition, the outer surface of the partition is an arc / plane adapted to the arc surface / groove bottom, the inner surface of the partition includes a first inclined surface extending obliquely from the necking to the opening, and a second inclined surface extending from the opening to the necking, the end of the first inclined surface away from the outer surface of the partition is connected to the end of the second inclined surface away from the outer surface of the partition, the inclination angle of the first inclined surface is smaller than the inclination angle of the second inclined surface, and the partitions on the arc surface and the partitions on the groove are staggered in the direction of the major axis of the ellipsoid.

[0010] This preferred solution, through the arrangement of the first inclined surface and the second inclined surface, guides the flow of bile while increasing the contact area of ​​the bile on the partition, thereby further facilitating the precipitation of bezoar crystals; and by staggering the partitions on the arc surface and the partitions on the groove in the direction of the long axis of the ellipsoid, it is convenient to improve the anti-extrusion strength of the half cover.

[0011] Preferably, the plurality of partition holes are arranged in parallel, the width of the partition holes is greater than or equal to 1.5 mm, and the distance between two adjacent partition holes on the bottom / arc surface of the groove is less than or equal to 2 mm.

[0012] The preferred solution facilitates bile to enter the bed through the setting of the partition hole specifications, and increases the contact area with the bed, which is beneficial to the deposition of bezoar crystals.

[0013] Preferably, a core cotton ball is provided in the center of the inner cavity of the bed body, and a plurality of thin lines connected to the half cover body are connected to the core cotton ball.

[0014] In this preferred solution, by setting the core cotton ball, the flow rate of bile into the bed is slowed down when the bile passes through the core cotton ball, which facilitates the deposition of bezoar crystals on the bed.

[0015] Preferably, the thin wires are evenly arranged along the circumference, and the core cotton ball is suspended.

[0016] This preferred solution ensures that the core cotton ball is evenly stressed in the circumferential direction by arranging the thin wires evenly along the circumference, thereby ensuring that the core cotton ball is located in the center of the bed body cavity; and reduces the contact of the core cotton ball with the inner surface of the half cover by arranging the core cotton ball in the air.

[0017] Preferably, the thin wire passes around the partition holes on the two half cover bodies to connect the two half cover bodies, and the two partition holes are arranged opposite to and adjacent to each other.

[0018] In this preferred solution, the thin wire passes around two adjacent partition holes on the two half-cover bodies, thereby achieving the connection and fixation of the two half-cover bodies. At the same time, the thin wire is also used to support the core cotton ball, thereby achieving full utilization of the thin wire.

[0019] Preferably, the volume of the core cotton ball is 0.1-0.2 times the volume of the bed body.

[0020] This preferred solution limits the volume of the core cotton ball, thereby facilitating more bile to contact the core cotton ball, thereby facilitating the crystallization and deposition of bezoar on the core cotton ball.

[0021] Preferably, the constricted opening of at least one of the half-cover bodies is detachably connected to the inner wall of the gallbladder via a fixing line.

[0022] In this preferred solution, when removing the bed from the gallbladder, it is only necessary to cut the fixing wires, thereby facilitating the removal of the bed from the gallbladder.

[0023] A method for using an inducing device for promoting the precipitation of bezoar crystals comprises the following steps:

[0024] First, the bovine gallbladder is cut open, and one end of the bed is placed in the direction of the gallbladder neck and implanted into the gallbladder cavity, ensuring that the bed completely passes through the intercostal incision and enters the deep part of the gallbladder. Then, the end of the fixing thread is fixed to the inner wall of the gallbladder inside the gallbladder incision with one needle, and then sutured. By staggering the grooves and curved surfaces, the inner surface of the bed is made uneven, so that the bed is not easy to twist after being placed in the body of the bovine gallbladder.

[0025] The bile in the gallbladder flows into the bed from the constricted openings of the two half-covers. The groove wall and the first inclined surface increase the contact area between the bed and the bile, which is beneficial to the precipitation of bezoar crystals. The core cotton ball slows down the bile flow rate, which facilitates the precipitation of bezoar crystals.

[0026] Finally, cut the fixing rope, remove the bed from the gallbladder, and dry it. Then remove the cloth bag from the two half-cover bodies, cut the thin wire, take out the core cotton ball, and then use a blade to scrape off the dried bezoar, and seal the bezoar and store it in a dark place.

[0027] The beneficial effects of the present invention are as follows: through the arrangement of the grooves, the arc surface and the grooves of the half cover are arranged alternately in the circumferential direction, so that the inner and outer surfaces of the half cover are uneven, and the uneven inner surface causes part of the bile to flow on the groove walls when bile flows from the inside to the outside, thereby increasing the contact area between the bile and the half cover, which is convenient for the precipitation of bezoar crystals. At the same time, the uneven outer surface makes it difficult for the bed to twist when it is placed in the body of the cattle gallbladder; through the arrangement of the core cotton ball, the flow rate of bile entering the bed is slowed down, which is convenient for the deposition of bezoar crystals on the bed; through the arrangement of the fixing line, when the bed is taken out of the gallbladder, it is only necessary to cut the thin line, thereby facilitating the removal of the bed from the gallbladder. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 It is an explosion diagram of the bed of the present invention;

[0029] Figure 2 It is a schematic diagram of the main view of two half covers of the present invention;

[0030] Figure 3 It is a schematic top view of two half covers of the present invention;

[0031] Figure 4 for Figure 3 Schematic diagram of the cross section at AA;

[0032] Figure 5 This is a schematic diagram of the main structure of the present invention;

[0033] Figure 6 It is a three-dimensional schematic diagram of two half covers of the present invention;

[0034] In the figure, 1, necking, 2, curved surface, 3, partition hole, 4, open mouth, 5, groove, 6, thin wire, 7, core cotton ball, 8, thin rope, 9, cloth bag, 10, first inclined surface, 11, partition, 12, second inclined surface, 13, groove wall, 14, half cover. DETAILED DESCRIPTION

[0035] In order to clearly illustrate the technical features of this solution, this solution is described below through specific implementation methods.

[0036] Refer to the attached Figure 1-6 The present invention provides an inducing device for promoting the precipitation of bezoar crystals and a method for using the same, comprising a bed and a cloth bag 9, wherein the bed comprises an ellipsoidal skeleton and a core cotton ball 7, the cloth bag 9 wraps the skeleton, and the core cotton ball 7 is suspended at the center of the skeleton, and the volume of the core cotton ball 7 is 0.1-0.2 times the volume of the inner cavity of the skeleton.

[0037] The skeleton includes two semi-ellipsoidal half-cover bodies 14 that are relatively arranged and have a semi-ellipsoidal shape. The large-diameter end of the half-cover body 14 is an opening 4, and the small-diameter end is a constricted opening 1. The openings 4 of the two half-cover bodies 14 are in contact with each other. The two half-cover bodies 14 are an upper cover and a lower cover, that is, the opening 4 of the upper cover and the opening 4 of the lower cover are relatively arranged and in contact with each other.

[0038] The outer surface of the half cover body 14 is provided with a plurality of grooves 5 extending inward and evenly arranged along the circumference of the half cover body 14. The two ends of the grooves 5 extend to the open opening 4 and the shrinkage 1 of the half cover body 14 respectively. The plurality of grooves 5 divide the outer surface of the half cover body 14 into a plurality of arc surfaces 2 evenly arranged along the circumference. The arc surfaces 2 and the grooves 5 are staggered so that the inner and outer surfaces of the half cover body 14 are uneven. The arc surfaces 2 and the bottom of the grooves 5 are provided with a plurality of partition holes 3 arranged along the extension direction of the arc surfaces 2 and connected to the inner cavity of the half cover body 14.

[0039] The two partition holes 3 are separated by a partition 11, and the outer surface of the partition 11 is an arc / plane that matches the bottom of the arc surface 2 / groove 5. The inner surface of the partition 11 includes a first inclined surface 10 extending obliquely from the necking 1 to the opening 4, and a second inclined surface 12 extending from the opening 4 to the necking 1. The end of the first inclined surface 10 away from the outer surface of the partition 11 is connected to the end of the second inclined surface 12 away from the outer surface of the partition 11. The inclination angle of the first inclined surface 10 is smaller than the inclination angle of the second inclined surface 12. The partitions 11 on the arc surface 2 and the partitions 11 on the groove 5 are staggered in the direction of the long axis of the ellipsoid, and the connection between the first inclined surface 10 and the second inclined surface 12 has a smooth transition.

[0040] The arrangement of the groove wall 13 and the partition 11 is conducive to increasing the contact area between the bile and the bed, thereby facilitating the precipitation of bezoar crystals.

[0041] The plurality of partition holes 3 are arranged in parallel, the width of the partition hole 3 is greater than or equal to 1.5 mm, and the distance between two adjacent partition holes 3 on the groove bottom / arc surface 2 of the groove 5 is less than or equal to 2 mm, that is, the height of the partition plate 11 is less than or equal to 2 mm.

[0042] The partition holes 3 located at the bottom of the groove 5 are all rectangular through-holes with the same size, and the partition holes 3 located on the arc surface 2 are trapezoidal holes adapted to the width of the arc surface 2 .

[0043] The constricted opening 1 of the upper cover and / or the lower cover is connected with a fixing line which passes through the cloth bag 9 and is detachably connected to the inner wall of the gallbladder.

[0044] The cloth bag 9 wraps the frame and covers all the partition holes 3. The two openings of the cloth bag 9 extend to the upper cover necking 1 and the lower cover necking 1 respectively, and are fastened at the two neckings 1 by a thin rope 8 passing through two adjacent partition holes 3.

[0045] The core cotton ball 7 is connected to a number of thin wires 6 connected to the half cover body 14. The thin wires 6 are evenly arranged along the circumference. The core cotton ball 7 is suspended at the center of the skeleton ellipsoid and is directly impacted by the bile entering the bed, thereby slowing down the flow rate of bile entering the bed body, facilitating the deposition of bezoar crystals on the bed body. The thin wires 6 also bypass the partition holes 3 on the two half cover bodies 14 to connect the two half cover bodies 14. The two partition holes 3 are arranged opposite and adjacent to each other.

[0046] In particular, the two half-covers 14 can be glued together on their opposing surfaces. When using the present invention, the cow gallbladder is first cut open, and one end of the bed is implanted into the gallbladder cavity toward the gallbladder neck, ensuring that the bed completely passes through the intercostal incision and enters the deep part of the gallbladder. The end of the fixing thread is then fixed to the inner wall of the gallbladder inside the gallbladder incision with a needle, and then sutured. The inner surface of the bed is unevenly arranged by staggered arrangement of grooves and curved surfaces, so that the bed is not easily twisted after being placed in the body of the cow gallbladder.

[0047] The bile in the gallbladder flows into the bed from the constriction 1 of the two half-cover bodies. The arrangement of the groove wall increases the contact area between the bed and the bile, which is beneficial to the precipitation of bezoar crystals. The arrangement of the core cotton ball 7 slows down the bile flow rate, which is convenient for the deposition of bezoar crystals.

[0048] Finally, cut the fixing rope, take the bed out of the gallbladder, wipe the surface lightly with absorbent paper, and then put the bed into the drying box for rapid drying at a drying temperature of 40-50°C. Then remove the cloth bag from the two half covers, cut the thin wire 6, separate the upper cover and the lower cover, take out the core cotton ball 7, and then scrape off the dried bezoar with a blade, and seal the bezoar and store it in a dark place.

[0049] When the bed is placed into the gallbladder, the cow, which has been well prepared before surgery, is given general anesthesia and layered infiltration anesthesia of the intercostal tissue is performed simultaneously;

[0050] The cow is placed in a left-side lying position, and the body is adjusted so that the back is higher than the head to facilitate the flow of oral secretions.

[0051] Carefully shave the hair around the second to last intercostal space on the right side, then scrub the skin of the surgical area with 0.1% chlorhexidine solution and wipe dry with sterile gauze; finally, disinfect the skin of the surgical area with 2% iodine tincture solution and 75% alcohol solution.

[0052] In the middle of the two ribs of the surgical site, the skin, cutaneous muscles, and external intercostal muscles are incised in layers, and the internal intercostal muscles are bluntly separated to stop bleeding completely. Then, a retractor is used to enlarge the wound, and the exposed peritoneum is clamped with tweezers and slightly lifted. A small cut is made with scissors, and then the peritoneum is cut from the small cut to the upper and lower ends to expose the caudate lobe of the liver.

[0053] Insert your fingers into the abdominal cavity, slide forward and upward along the smooth peritoneum to touch the edge of the liver, and then touch forward and downward along the edge of the liver to feel the full gallbladder; then pinch the bottom of the gallbladder, carefully and slowly pull the gallbladder to the outside of the intercostal incision, wrap sterilized saline gauze around the neck of the gallbladder to isolate and fix it. The area with sparse blood vessels at the bottom of the gallbladder is the surgical incision; make 4 traction lines at both ends and both sides of the predetermined incision of the gallbladder. The sutures only penetrate the serosal muscle layer of the gallbladder wall, and the assistant pulls them tight.

[0054] The assistant and the surgeon pull four traction lines respectively. The surgeon uses a scalpel to vertically pierce the gallbladder in the avascular area at the bottom of the gallbladder, and then uses scissors to longitudinally expand the incision to 3-4 cm.

[0055] Use three tissue forceps or small hemostats to clamp the edges of the gallbladder incision at equal distances, fully open the incision, and then the surgeon implants one end of the bed into the gallbladder cavity toward the gallbladder neck, ensuring that the entire bed passes through the intercostal incision and enters deep into the gallbladder. The depth of the bed inserted into the gallbladder should be appropriate to be located in the gallbladder body; then fix the end of the fixing line tied to the tail end of the bed to the inner wall of the gallbladder inside the gallbladder incision with a needle.

[0056] The gallbladder incision is sutured in two layers with 2-0 absorbable sutures. The first layer is a simple continuous suture of the entire layer, and the second layer is a continuous inversion suture of the seromuscular layer. Both layers must be sutured tightly to prevent bile from overflowing.

[0057] 5 mL of specially cultured bacterial solution containing non-pathogenic Escherichia coli was extracted and the injection needle was inserted into the gallbladder through the gallbladder wall. The gallbladder incision was rinsed with sterile saline, a small amount of erythromycin ointment was applied, and then the solution was returned to the abdominal cavity.

[0058] When harvesting bezoar, the peritoneum is cut open from the original access point, the gallbladder is explored and pulled to the intercostal incision, the gallbladder is then cut open, and the bed is removed using long hemostats. Compared to the traditional bed, the improved detachable bed in the above embodiment greatly reduces the difficulty of harvesting bezoar while increasing the yield of bezoar, representing a significant improvement and upgrade in bezoar cultivation auxiliary equipment.

[0059] Of course, the above description is not limited to the above examples. Technical features not described in the present invention can be achieved by or by adopting existing technologies, which will not be described here. The above embodiments and drawings are only used to illustrate the technical solutions of the present invention and are not limitations of the present invention. The present invention is described in detail with reference to the preferred implementation methods. Ordinary technicians in this field should understand that changes, modifications, additions or substitutions made by ordinary technicians in this technical field within the essential scope of the present invention do not depart from the purpose of the present invention and should also fall within the scope of protection of the claims of the present invention.

Claims

1. A device for promoting the precipitation of bezoar crystals, comprising a bed, wherein the bed comprises two semi-ellipsoidal half covers (14) arranged opposite to each other and detachably connected to each other on opposite surfaces, characterized in that: The outer surface of the half cover body (14) is provided with a plurality of grooves (5) extending inward and evenly arranged along the circumference of the half cover body (14); the plurality of grooves (5) divide the outer surface of the half cover body (14) into a plurality of arc surfaces (2) evenly arranged along the circumference; the grooves (5) and the arc surfaces (2) are arranged in a staggered manner; the arc surfaces (2) and the bottom of the grooves are both provided with a plurality of partition holes (3) arranged along the extension direction of the arc surfaces (2) and communicating with the inner cavity of the half cover body (14); The two ends of the groove (5) extend to the open opening (4) and the shrinkage opening (1) of the half cover (14), respectively, and the bottom of the groove (5) is a plane. The partition (11) is separated from the two partition holes (3). The outer surface of the partition (11) adapted to the arc surface (2) is arc-shaped, and the outer surface of the partition (11) adapted to the bottom of the groove is flat. The inner surface of the partition (11) includes a first inclined surface (10) extending obliquely from the necking (1) to the opening (4), and a second inclined surface (12) extending from the opening (4) to the necking (1). One end of the first inclined surface (10) away from the outer surface of the partition (11) is connected to one end of the second inclined surface (12) away from the outer surface of the partition (11). The inclination angle of the first inclined surface (10) is smaller than the inclination angle of the second inclined surface (12). The partition (11) on the arc surface (2) and the partition (11) on the groove (5) are staggered in the direction of the major axis of the ellipsoid.

2. The device for promoting the precipitation of bezoar crystals according to claim 1, wherein: The plurality of partition holes (3) are arranged in parallel, the width of the partition holes (3) is greater than or equal to 1.5 mm, the distance between two adjacent partition holes (3) on the bottom of the groove (5) is less than or equal to 2 mm, and the distance between two adjacent partition holes (3) on the arc surface (2) is less than or equal to 2 mm.

3. The device for inducing the precipitation of bezoar crystals according to claim 1, wherein: A core cotton ball (7) is also provided at the center of the inner cavity of the bed body, and a plurality of thin wires (6) connected to the half cover body (14) are connected to the core cotton ball (7).

4. The device for inducing the precipitation of bezoar crystals according to claim 3, wherein: The thin wires (6) are evenly arranged along the circumference, and the core cotton ball (7) is suspended.

5. The device for promoting the precipitation of bezoar crystals according to claim 3, wherein: The thin wire (6) passes around the partition holes (3) on the two half cover bodies (14) to connect the two half cover bodies (14), and the two partition holes (3) are arranged opposite to each other and adjacent to each other.

6. The device for promoting the precipitation of bezoar crystals according to claim 3, wherein: The volume of the core cotton ball (7) is 0.1-0.2 times the volume of the bed.

7. The device for promoting the precipitation of bezoar crystals according to claim 3, characterized in that: The constricted opening (1) of at least one of the half-cover bodies (14) is detachably connected to the inner wall of the gallbladder via a fixing line.

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