A fully automatic sample test tube online refrigerator control system

Abstract

The present invention belongs to the field of sample control technology, and specifically discloses a fully automatic sample test tube online refrigerator control system, which includes: a placement information import module, a sample status monitoring module, a placement status analysis module, a sample failure processing terminal, an environmental difference analysis module, an information library, and an environmental control execution terminal. The present invention analyzes the sample placement status according to the monitoring information and identification information of each placed sample, and performs failure processing and placement difference analysis according to the placement status, and then confirms the control information, thereby avoiding the one-sidedness of currently relying only on the instant analysis and control of the currently collected monitoring data, and realizes the periodic tracking and analysis of different placed samples, thereby ensuring the timeliness and effectiveness of the environmental control of the placed samples and the timeliness of the processing of invalid samples, while ensuring the stability and activity of the placed samples as much as possible, providing a guarantee for the subsequent call of samples.

Description

Technical Field

[0001] The invention belongs to the technical field of sample control and relates to a full-automatic sample test tube online refrigerator control system. Background Art

[0002] Biomedical research and clinical trials require the storage of a large number of biological samples, such as blood, tissue, DNA, etc. These samples are sensitive to temperature and must be kept in a strictly controlled temperature environment, so they are stored in corresponding refrigerators. In order to ensure the stability and activity of the samples, the environment in the refrigerator needs to be controlled.

[0003] At present, the control of the sample environment in the refrigerator is mainly carried out by collecting the status of the sample and controlling the temperature and humidity accordingly according to the collected status information. Obviously, the current sample refrigerator control still has the following deficiencies: 1. Real-time control: The existing control method relies on real-time analysis and control of the currently collected monitoring data. This method lacks periodic tracking of different samples, resulting in insufficient timeliness of sample environment control. At the same time, due to the lack of predictive control mechanism, it is impossible to foresee and adjust environmental parameters in advance, which affects the effectiveness of sample environment control.

[0004] 2. Insufficient accuracy and independence of environmental control: The storage differences of different samples placed in the same control area were not analyzed. Refrigerators usually perform overall environmental control, which makes it difficult to ensure the adaptability of environmental control for a single sample.

[0005] 3. Insufficient automation: For some samples with higher requirements, they are still tested manually, which is highly random and cannot be automatically tested. They are mainly handled based on personal experience, which is prone to deviations. Summary of the invention

[0006] In view of this, in order to solve the problems raised in the above background technology, a fully automatic sample test tube online refrigerator control system is now proposed.

[0007] The purpose of the present invention can be achieved through the following technical solutions: The present invention provides a fully automatic sample test tube online refrigerator control system, the system includes: a placement information import module, which is used to record the placement refrigerator to which the current sample belongs as the target placement device, import the location of the waste area of ​​the target placement device, and the set temperature value, set humidity value and corresponding number of each placed sample of each storage area.

[0008] The sample status monitoring module is used to monitor and identify each placed sample in each storage area through a monitoring device, obtain a monitoring image and identification information, and add the monitoring image to the identification information of the corresponding placed sample.

[0009] The placement status analysis module is used to perform sample placement status analysis based on the monitoring image and identification information, and output status information of each placed sample in each storage area.

[0010] The sample failure processing terminal is used to record the placement samples with a failure status as unqualified samples and place the unqualified samples in the waste area of ​​the target placement device.

[0011] The environment difference analysis module is used to record the placement samples in the valid state as the control samples, perform the placement difference analysis on each control sample in each storage area, and output the placement difference analysis result.

[0012] The information base is used to store the reference index values ​​of each sample index under each placement time of the samples placed in each storage area, store the set control temperature range and set control humidity range of each storage area, and store the characterization index value range corresponding to each temperature state and each humidity state of the placed samples.

[0013] The environmental control execution terminal is used to confirm each environmental control area and the environmental control mode of each environmental control area, and at the same time confirm the control information of each environmental control area and perform corresponding environmental control.

[0014] Compared with the prior art, the beneficial effects of the present invention are as follows: (1) The present invention analyzes the sample placement status according to the monitoring information and identification information of each placed sample, and performs failure processing and placement difference analysis according to the placement status, thereby confirming the control information and performing corresponding environmental control, thereby effectively solving the current problems existing in timeliness control, avoiding the one-sidedness of currently relying only on the instant analysis and control of the currently collected monitoring data, and realizing the periodic tracking and analysis of different placed samples, thereby ensuring the timeliness of the environmental control of the placed samples and the timeliness of the processing of invalid samples, while ensuring the stability and activity of the placed samples as much as possible, providing a guarantee for the subsequent call of samples.

[0015] (2) The present invention solves the problem of insufficient automation in the current monitoring of some samples by utilizing monitoring equipment to monitor and identify each placed sample in each storage area, and realizes the automated monitoring of all placed samples in different storage areas, thereby removing the limitation that some samples are still tested manually, thereby avoiding the large randomness of personnel testing, and at the same time reducing the control deviation caused by processing based on personal experience, and also realizing the one-by-one monitoring of all placed samples, ensuring the coverage and scientific nature of the monitoring.

[0016] (3) The present invention provides a predictive control mechanism by setting a placement state correction factor according to the identification information, thereby correcting the statistical placement state consistency, and realizing predictive evaluation of different placement samples in different storage areas, thereby making up for the current shortcomings of being unable to foresee and adjust environmental parameters in advance, thereby ensuring the representativeness and authenticity of subsequent placement sample state confirmation results, thereby further ensuring the effectiveness and rationality of subsequent placement sample environmental control.

[0017] (4) The present invention solves the problem of not analyzing the storage difference status of different samples placed in the same control area by performing placement difference analysis on each regulated sample in each storage area. It intuitively displays the storage difference status of differently placed samples in the same storage area, thereby facilitating subsequent targeted environmental control.

[0018] (5) The present invention improves the accuracy of environmental control corresponding to the placed samples by confirming the environmental control area and the environmental control mode according to the statistical placement state difference and placement state consistency. At the same time, targeted environmental control information is confirmed according to different environmental modes, which improves the independence of the environmental control corresponding to the placed samples, thereby compensating for the shortcomings of the current overall environmental control, ensuring the adaptability of the environmental control of a single sample and meeting the unique needs of each placed sample as much as possible. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings required for describing the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other accompanying drawings can be obtained based on these accompanying drawings without paying creative work.

[0020] Figure 1 It is a schematic diagram of the connection of each module of the system of the present invention.

[0021] Figure 2 Schematic diagram of the placement of sample monitoring equipment.

[0022] Figure numerals: 1. Robot gripper, 2. High-resolution visual camera, 3. Barcode scanner, 4. Robot. DETAILED DESCRIPTION

[0023] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0024] See also Figure 1 As shown, the present invention provides a fully automatic sample test tube online refrigerator control system, which includes: a placement information import module, a sample status monitoring module, a placement status analysis module, a sample failure processing terminal, an environmental difference analysis module, an information library and an environmental control execution terminal.

[0025] In the above, the placement information import module is respectively connected to the sample status monitoring module, the sample failure processing terminal and the environmental control execution terminal, the sample status monitoring module is connected to the placement status analysis module, the placement status analysis module is also respectively connected to the sample failure processing terminal, the environmental difference analysis module, the information library and the environmental control execution terminal, and the environmental control execution terminal is also respectively connected to the environmental difference analysis module and the information library.

[0026] The placement information import module is used to record the placement refrigerator to which the current sample belongs as the target placement device, import the location of the discarded area of ​​the target placement device, and the set temperature value, set humidity value and number of each storage area corresponding to each placement sample.

[0027] The sample status monitoring module is used to monitor and identify each placed sample in each storage area through a monitoring device, obtain a monitoring image and identification information, and add the monitoring image to the identification information of the corresponding placed sample.

[0028] Specifically, the monitoring equipment includes a high-resolution visual camera and a barcode scanner.

[0029] In addition, please refer to Figure 2 As shown, the placement container described in the present invention is a test tube. In order to facilitate subsequent understanding, the specific implementation process of monitoring and identifying each placed sample in each storage area by monitoring equipment is as follows: start the manipulator gripper 1 of the manipulator 4 of the target device to clamp the corresponding test tube in each storage area in turn, and use the high-resolution visual camera 2 to perform image monitoring of the placed samples in each test tube in each storage area to obtain the monitoring image of each placed sample in each storage area, and at the same time use the barcode scanner 3 to identify the QR code carried by each test tube in each storage area to obtain the identification information of each placed sample in each storage area.

[0030] It should also be added that, the present invention adds the monitoring image to the identification information of the corresponding placement sample, which means associating the monitoring image with the QR code of the placement sample, and then adding it to the identification information corresponding to the placement sample. The specific adding process is a relatively mature technology and will not be described in detail here.

[0031] The embodiment of the present invention solves the problem of insufficient automation in the current monitoring of some samples by utilizing monitoring equipment to monitor and identify each placed sample in each storage area, realizes the automated monitoring of all placed samples in different storage areas, removes the limitation that some samples are still tested manually, thereby avoiding the large randomness of personnel testing, and also reduces the control deviation caused by processing based on personal experience, and also realizes the one-by-one monitoring of all placed samples, ensuring the coverage and scientific nature of the monitoring.

[0032] The placement status analysis module is used to perform sample placement status analysis based on the monitoring image and identification information, and output status information of each placed sample in each storage area.

[0033] Specifically, the sample placement status analysis is performed, including: S1, using image recognition technology to identify the monitoring image of each placed sample in each storage area, obtain the identification value of each sample indicator, and count the placement status consistency of each placed sample in each storage area, recorded as , Indicates the storage area number, , Indicates the placement sample number, .

[0034] S2, extracting the monitoring images of each cumulative recognition from the recognition information, and setting the placement state correction factor of each placed sample in each storage area .

[0035] S3. As the corrected placement state consistency of each placement sample in each storage area, it is recorded as .

[0036] S4. If the corrected placement state match degree of a placement sample in a storage area is less than 0, the state of the placement sample in the storage area is invalid, otherwise it is valid, thereby obtaining the state of each placement sample in each storage area.

[0037] Furthermore, in step S1, the placement state matching degree of each placement sample in each storage area is counted, including: S11, extracting the placement time point from the identification information, and then obtaining the placement duration.

[0038] S12, extracting from the information base the reference index value of each sample index under the cumulative placement time corresponding to each placement sample in each storage area.

[0039] Understandably, each sample indicator includes but is not limited to the color, transparency, shape and volume of the placed sample, wherein the identification value of color is the chromaticity value, the identification value of transparency is the transparency value, the identification value of shape is the shape outline, and the identification value of volume is the volume value.

[0040] S13, compare the reference index value and the identification value of the same sample index. If the difference between the identification value and the reference index value of a sample index exceeds the set allowable range, mark the sample index as a deviation index, count the number of deviation indicators, and compare it with the number of sample indicators to obtain the deviation index ratio of each sample placed in each storage area. .

[0041] S14, taking the absolute value of the difference between the identification value corresponding to each deviation index and its reference index value as the deviation value of each deviation index, recorded as , Indicates the deviation indicator number, .

[0042] S15: Count the placement status matching degree of each placed sample in each storage area , , is a natural constant, is the reference deviation index ratio, For the The reference deviation value of the deviation index, is the number of deviation indicators.

[0043] In a specific embodiment, when counting the placement state consistency of each placement sample in each storage area, a reference deviation index is usually used for evaluation. This index indicates the degree of difference between the actual measurement value and the reference value. Generally speaking, the smaller the value of the reference deviation index, the closer the actual value is to the reference value, indicating that the placement state consistency is higher, that is, and The smaller the value, the greater the consistency of the corresponding placement state. Specifically, The specific value of depends mainly on the number of sample indicators. When the number of sample indicators is 10, the specific value of the allowable deviation indicator number can be 2, that is, The value can be taken as 0.5. The deviation value of each deviation index is mainly extracted from the placement status evaluation technical table of the placement sample.

[0044] Furthermore, the setting of the placement state correction factor of each placed sample in each storage area in step S2 includes: S21, according to The statistical method is similar to that of the method for calculating the degree of coincidence of the placement status of each placed sample in each storage area during each cumulative recognition.

[0045] S22, constructing a placement state curve of each placement sample in each storage area with the accumulated recognition order as the horizontal coordinate and the placement state matching degree as the vertical coordinate.

[0046] S23, locating a slope from the placement state curve as the placement state change rate, normalizing the placement state change rate, using the normalization result as the independent variable of the Sigmoid function, and then obtaining the placement state correction factor of each placement sample in each storage area through the Sigmoid function statistics.

[0047] It should be added that normalizing the placement state change rate refers to subtracting a preset reference placement state change rate from the placement state change rate, comparing the difference with the preset reference placement state change rate, and taking the ratio as the normalization result of the placement state change rate.

[0048] It should also be added that the reference placement state change rate is mainly extracted from the placement state evaluation technical table of the placement sample, and the reference placement state change rate corresponding to the placement sample at each storage time is extracted. Based on the cumulative placement time of the placement sample, the reference placement state change rate corresponding to the cumulative placement time of the placement sample is obtained and used as the pre-set reference placement state change rate.

[0049] In a specific embodiment, in order to ensure the effectiveness of the correction of the placement state correction factor, the placement state correction factor can also be corrected, that is, a secondary correction factor is set, wherein the setting process of the secondary correction factor is: D1, locating the number of fluctuation points and the placement state fit deviation between each fluctuation point from the placement state curve.

[0050] D2. Calculate the variance of the placement state fit deviation between each fluctuation point, and use the calculation result as the fluctuation difference.

[0051] D3. Subtract the number of fluctuation points from the preset number of reference fluctuation points, compare the difference with the preset number of reference fluctuation points, and use the ratio as the fluctuation excess.

[0052] D4. Subtract the fluctuation difference from the preset reference fluctuation difference, compare the difference with the preset reference fluctuation difference, take the ratio as the fluctuation difference excess, and then take the fluctuation excess and the fluctuation difference excess as independent variables of the Sigmoid function, set the secondary correction factor through the Sigmoid function, and correct the placement state correction factor through the secondary correction factor in the same way as the correction method of the placement state fit.

[0053] It should be added that the number of pre-set reference fluctuation points is mainly set according to the cumulative number of identification times. For example, if the cumulative number of identification times is 20, 3 can be selected as the pre-set number of reference fluctuation points. When the variance calculation result is 0, it indicates that there is no reference fluctuation difference at this time, that is, the fluctuation difference value is the minimum. At this time, the reference fluctuation difference can be set with 0 as the boundary. Specifically, 0.1 can be used as the pre-set reference fluctuation difference.

[0054] It should also be added that the placement state change rate mentioned in the present invention refers to the slope of the regression line corresponding to the placement state curve. When the number of fluctuation points is more and the fluctuation amplitude is larger, the error of using the slope of the regression line corresponding to the placement state curve to represent the placement state change rate will be larger. Therefore, the secondary correction factor is set based on the two parameter dimensions of the number of fluctuation points and the difference in placement state fit between the fluctuation points to ensure the effectiveness of the correction.

[0055] The embodiment of the present invention provides a predictive control mechanism by setting a placement state correction factor according to identification information and then correcting the statistical placement state consistency, thereby realizing predictive evaluation of different placement samples in different storage areas, making up for the current shortcomings of environmental parameters that cannot be foreseen and adjusted in advance, and thus ensuring the representativeness and authenticity of subsequent placement sample state confirmation results, thereby further ensuring the effectiveness and rationality of subsequent placement sample environmental control.

[0056] The sample failure processing terminal is used to record the placement samples in the failed state as unqualified samples, and place the unqualified samples in the waste area of ​​the target placement device.

[0057] The environment difference analysis module is used to record the placement samples in the valid state as control samples, perform placement difference analysis on each control sample in each storage area, and output the placement difference analysis result.

[0058] Specifically, the placement difference analysis is performed, including: performing variance calculation on the corrected placement state consistency of each control sample in the same storage area, using the variance calculation result as the placement state difference, and then obtaining the placement state difference of the control samples in each storage area, recorded as ,Will As a result of the placement difference analysis.

[0059] The information library is used to store reference index values ​​of each sample index under each placement time of the samples placed in each storage area, store the set control temperature interval and the set control humidity interval of each storage area, and store the characterization index value interval corresponding to each temperature state and each humidity state of the placed samples.

[0060] The environmental control execution terminal is used to confirm each environmental control area and the environmental control mode of each environmental control area, and at the same time confirm the control information of each environmental control area, and perform corresponding environmental control.

[0061] Specifically, confirming each environmental control area and the environmental control mode of each environmental control area includes: E1, placing the control sample in the storage area with a placement state difference greater than the set reference placement state difference As condition 1.

[0062] It should be added that The specific value of can be obtained by extracting it from the sample environmental control technology table.

[0063] E2. The corrected placement state consistency of a certain regulated sample in the storage area is less than the set placement state consistency, which is used as condition 2.

[0064] E3. If a storage area meets condition 1 or condition 2, the storage area is recorded as an environmental control area, thereby obtaining various environmental control areas.

[0065] E4. If a certain environmental control area only meets condition 1, position control shall be used as the environmental control mode of the environmental control area.

[0066] E5. If a certain environmental control area only meets condition 2, the environmental control will be used as the environmental control mode of the environmental control area.

[0067] E6. If a certain environmental control area satisfies both conditions 1 and 2, the location-environmental control is used as the environmental control mode of the environmental control area, thereby obtaining the environmental control mode of each environmental control area.

[0068] Specifically, confirming the control information of each environmental control area includes: J1, recording the environmental control area where the environmental control mode is environmental control as area A, extracting the characterization index value intervals corresponding to each temperature state and each humidity state of the placement sample from the information database, and confirming the control environment items and control methods of area A, wherein the control environment items are one or more of temperature and humidity, and the control method is one of increasing or decreasing.

[0069] In a specific embodiment, when the temperature of the refrigerator is low, the liquid containing the sample may crystallize or show frozen characteristics. On the contrary, if the temperature of the refrigerator is high, the liquid containing the sample may show signs of heating. When the temperature is low or high, the transparency and color of the sample will change. For example, transparency or color can be selected as the temperature characterization index, and the transparency value can be used as the identification value of transparency, and the chromaticity value can be used as the identification value of color. When the humidity of the refrigerator is low or high, the color of the sample will change. For example, the humidity characterization index can be the sample color of the sample, and the identification value is the chromaticity value.

[0070] J2. According to the control environment item and the environment control method, determine the control value of the control environment item, and use the control environment item and the control value of the control environment item as the control information of area A.

[0071] J3. The environmental control area where the environmental control mode is position control is recorded as area B, and the suitable adjustment area of ​​each control sample in area B is confirmed and used as its control information.

[0072] J4. Record the environmental control area whose environmental control mode is position-environmental control as area C, and use the control information of the A-type area and area B as the control information of area C, so as to confirm and obtain the control information of each environmental control area in turn.

[0073] The embodiments of the present invention improve the accuracy of environmental control corresponding to the placed samples by confirming the environmental control area and the environmental control mode according to the statistical placement state difference and placement state consistency. At the same time, targeted environmental control information is confirmed according to different environmental modes, which improves the independence of the environmental control corresponding to the placed samples, thereby compensating for the shortcomings of the current overall environmental control, ensuring the adaptability of the environmental control of a single sample and meeting the unique needs of each placed sample as much as possible.

[0074] Furthermore, the supplementary process of confirming the control environment items and control methods of area A in step J1 is as follows: J11. Filter out the identification values ​​of the temperature characterization index and the humidity characterization index from the identification values ​​of each sample index corresponding to each placed sample in the A-type area.

[0075] J12. If the identification value of a certain temperature characterization index corresponding to a certain placement sample is within the characterization index value interval of a certain temperature state, then the temperature state is taken as the state to which the placement sample belongs, wherein the temperature state is one of a relatively high state, a moderate state and a relatively low state.

[0076] J13. Construct a temperature state set according to the states of each placed sample, and construct a humidity state set in the same way as the temperature state set, and traverse the temperature state set and the humidity state set.

[0077] J14. If there are placement samples in the temperature state set and the humidity state set that are in a high or low state, the temperature and humidity are used as the control environment items.

[0078] J15. If only the temperature state concentration contains placement samples that are in a high or low state, the temperature is used as the control environment item. If only the humidity state concentration contains placement samples that are in a high or low state, the humidity is used as the control environment item.

[0079] J16. When the control environment item is temperature, if the temperature state is concentrated in a high state, lowering it will be used as the control method. If the temperature state is concentrated in a low state, increasing it will be used as the control method.

[0080] J17. When the controlled environment item is humidity, the control method of humidity is obtained by analyzing the control method corresponding to temperature in the same way.

[0081] J18. When the controlled environment items are temperature and humidity, the temperature control method and the humidity control method shall be used as the control methods under the control item.

[0082] In a specific embodiment, since the environmental control mode is environmental control, it means that the difference in the placement states of each placement sample in the same environmental control area is within the permitted range, and thus the placement states of each placement sample can be defaulted to be similar or the same, which can be regarded as being confirmed according to the confirmation method of the control environment item and the control method corresponding to one placement sample. At the same time, in the environmental control mode, the control environment items and the control methods in the same environmental control area are the same, that is, there is the possibility of not increasing and decreasing at the same time, but there are situations where some need to be increased and some remain unchanged, or some need to be decreased and some remain unchanged.

[0083] Further, in step J2, the control value of the control environment item is confirmed, including: J21, when the control environment item is temperature, the temperature control trend is counted, and the temperature control trend is matched and compared with the reference temperature control trend corresponding to each set control ratio to obtain the matched control ratio. .

[0084] Among them, the reference temperature control trend corresponding to each control ratio is obtained by extracting from the refrigerator environment control technology table.

[0085] Understandably, the statistical temperature control trend includes: extracting the corrected placement state consistency of each control sample in the A-type area, and selecting the minimum corrected placement state consistency , and extract the placement status difference of the control samples in the A area .

[0086] Statistical temperature control trend , , To set the reference placement state fit, To set the reference placement state match difference.

[0087] It should be added that It represents the temperature control trend correction factor, which is obtained by changing the Sigmoid function. Since the overall control needs to consider the overall control needs of each placement sample, it cannot be too extreme. When the minimum correction placement state consistency is used as the calculation of the correction placement state consistency for control analysis and subsequent control, there is a certain error. Therefore, a slight correction is made according to the difference in placement state in Class A area to ensure the suitability of subsequent environmental control.

[0088] In a specific embodiment, when the placement state fit is 0, it is in a critical fit state. The critical value is set to 0. The value is greater than 0. Specifically, The value can be 0.5, and when the placement state difference is 0, it indicates that the placement state difference is small at this time, that is, The value can be taken with 0 as the center value. Specifically, The value can be 0.1.

[0089] J22. Extract the set temperature value of the Class A area and record it as , and extract the set control temperature range of area A from the information database, and record the upper limit and lower limit of the control temperature range as and .

[0090] J23. When the control mode is to increase, As the control value, when the control mode is to reduce, as control value.

[0091] J24. When the controlled environment item is humidity, the corresponding controlled value is confirmed in the same way as when the controlled environment item is temperature.

[0092] J25. When the regulated environmental items are temperature and humidity, the regulated values ​​when the regulated environmental items are temperature and humidity are used as the regulated values ​​of the regulated environmental items.

[0093] Furthermore, step J3 confirms the suitable adjustment area for each control sample in area B, including: J31, confirming the control information of each control sample in area B in the same way as the control information of area A, and extracting the set control temperature range and set control humidity range of each storage area from the information library.

[0094] J32. The control sample whose control environment item is temperature is recorded as a temperature control sample. If the control value of the temperature control sample is within the set control temperature range of area B, area B is used as the suitable adjustment area for the temperature control sample. Otherwise, the control value of the temperature control sample is matched and compared with the set control temperature range of each storage area, and the matched storage area is used as the suitable adjustment area for the temperature control sample.

[0095] J33. Record the control sample whose control environment item is humidity as the humidity control sample, and confirm the suitable control area of ​​the humidity control sample in the same way as the confirmation method of the temperature control sample corresponding to the suitable adjustment area.

[0096] J34. Record the control sample whose control environment items are temperature and humidity as a comprehensive control sample, and confirm the suitable control area of ​​the comprehensive control sample through multiple control rules, and then obtain the suitable adjustment area of ​​each control sample in area B.

[0097] It should be added that the specific controls of the multiple control rules are as follows: U1. The control value of the control environment item of temperature is recorded as the temperature control value, and the control value of the control environment item of humidity is recorded as the humidity control value.

[0098] U2. Match and compare the temperature control value and humidity control value of the comprehensive control sample with the set control temperature range and the set control humidity range of each storage area respectively, and obtain the storage area that matches the corresponding temperature control value and the storage area that matches the corresponding humidity control value of the comprehensive control sample, which are recorded as temperature matching area and humidity matching area respectively.

[0099] U3. If the temperature matching area and the humidity matching area are the same area, this area is used as the suitable control area for the comprehensive control sample.

[0100] U4. If the temperature matching area and the humidity matching area are inconsistent, and when the humidity matching area is area B, the temperature matching area is used as the suitable control area for the comprehensive control sample.

[0101] U5. If the temperature matching area and the humidity matching area are inconsistent, and when the temperature matching area is area B, the humidity matching area is used as the suitable control area for the comprehensive control sample.

[0102] U6. If the temperature matching area and the humidity matching area are inconsistent, and when both the temperature matching area and the humidity matching area are not area B, the temperature matching area is used as the suitable control area for the comprehensive control sample.

[0103] In a specific embodiment, the present invention is based on biological samples, and the default priority storage adjustment principle is that the priority of temperature is greater than the priority of humidity, that is, the temperature matching area is used as the appropriate control area for the comprehensive control sample.

[0104] The embodiment of the present invention analyzes the sample placement status according to the monitoring information and identification information of each placed sample, performs failure processing and placement difference analysis according to the placement status, and then confirms the control information and performs corresponding environmental control, thereby effectively solving the current problems of timeliness control, avoiding the one-sidedness of currently relying only on real-time analysis and control of the currently collected monitoring data, and realizing periodic tracking and analysis of different placed samples, thereby ensuring the timeliness of the environmental control of the placed samples and the timeliness of the processing of invalid samples, while ensuring the stability and activity of the placed samples as much as possible, and providing guarantees for the calling of subsequent samples.

[0105] The above contents are merely examples and explanations of the concept of the present invention. Those skilled in the art may make various modifications or additions to the specific embodiments described or replace them in a similar manner. As long as they do not deviate from the concept of the invention or exceed the scope defined by the present invention, they shall all fall within the protection scope of the present invention.

Claims

1. A fully automatic sample test tube online refrigerator control system, characterized in that: The system includes: The placement information import module is used to record the placement refrigerator to which the current sample belongs as the target placement device, import the location of the discarded area of ​​the target placement device, and the set temperature value, set humidity value of each storage area and the number of each placement sample; The sample status monitoring module is used to monitor and identify each placed sample in each storage area through a monitoring device, obtain a monitoring image and identification information, and add the monitoring image to the identification information of the corresponding placed sample; A placement status analysis module, used to perform sample placement status analysis based on the monitoring image and identification information, and output status information of each placed sample in each storage area; A sample failure processing terminal is used to record the placement samples in the failed state as unqualified samples and place the unqualified samples in a discarded area of ​​the target placement device; An environmental difference analysis module is used to record the placement samples in a valid state as control samples, perform placement difference analysis on each control sample in each storage area, and output the placement difference analysis result; An information library is used to store reference index values ​​of various sample indicators of samples placed in each storage area at various placement times, store the set control temperature interval and the set control humidity interval of each storage area, and store the characterization index value interval corresponding to each temperature state and each humidity state of the placed samples; The environmental control execution terminal is used to confirm each environmental control area and the environmental control mode of each environmental control area, and at the same time confirm the control information of each environmental control area, and perform corresponding environmental control; The sample placement status analysis comprises: The monitoring images of each placed sample in each storage area are identified by image recognition technology to obtain the identification value of each sample indicator, and the placement status consistency of each placed sample in each storage area is counted and recorded as , Indicates the storage area number, , Indicates the placement sample number, ; Extract the monitoring images of each cumulative recognition from the recognition information, and set the placement state correction factor of each placed sample in each storage area. ; Will As the corrected placement state consistency of each placement sample in each storage area, it is recorded as ; If the corrected placement state match degree of a placement sample in a storage area is less than 0, the state of the placement sample in the storage area is invalid, otherwise it is valid, so as to obtain the state of each placement sample in each storage area; The counting of the placement state matching degree of each placement sample in each storage area includes: Extracting the placement time point from the identification information, and then obtaining the placement duration; Extracting reference index values ​​of each sample index under the cumulative placement time corresponding to each placement sample in each storage area from the information database; The reference index value and identification value of the same sample index are compared. If the difference between the identification value and the reference index value of a sample index exceeds the set allowable range, the sample index is marked as a deviation index. The number of deviation indicators is counted and compared with the number of sample indicators to obtain the deviation index ratio of each sample placed in each storage area. ; Take the absolute value of the difference between the corresponding identification value of each deviation index and its reference index value as the deviation value of each deviation index, recorded as , Indicates the deviation indicator number, ; Count the placement status consistency of each placed sample in each storage area , , is a natural constant, is the reference deviation index ratio, For the The reference deviation value of the deviation index, is the number of deviation indicators; The step of setting the placement state correction factor of each placement sample in each storage area includes: according to The statistical method is similar to the one used to count the placement status consistency of each placed sample in each storage area during each cumulative recognition; With the accumulated recognition order as the horizontal coordinate and the placement state matching degree as the vertical coordinate, a placement state curve of each placement sample in each storage area is constructed; The slope is located from the placement state curve as the placement state change rate, the placement state change rate is normalized, the normalized result is used as the independent variable of the Sigmoid function, and then the placement state correction factor of each placement sample in each storage area is obtained through the Sigmoid function statistics.

2. A fully automatic sample tube online refrigerator control system as claimed in claim 1, characterized in that: The placement difference analysis comprises: The variance of the corrected placement state consistency of each control sample in the same storage area is calculated, and the variance calculation result is used as the placement state difference, and then the placement state difference of the control samples in each storage area is obtained, which is recorded as ,Will As a result of the placement difference analysis.

3. A fully automatic sample tube online refrigerator control system as claimed in claim 2, characterized in that: The step of confirming each environmental control area and the environmental control mode of each environmental control area includes: The placement status difference of the control samples in the storage area is greater than the set reference placement status difference As condition 1; The corrected placement state consistency of a certain control sample in the storage area is less than the set placement state consistency as condition 2; If a storage area meets condition 1 or condition 2, the storage area is recorded as an environmental control area, thereby obtaining various environmental control areas; If a certain environmental control area only meets condition 1, position control is used as the environmental control mode of the environmental control area; If a certain environmental control area only meets condition 2, environmental control will be used as the environmental control mode of the environmental control area; If an environmental control area satisfies both conditions 1 and 2, the location-environmental control is used as the environmental control mode of the environmental control area, thereby obtaining the environmental control mode of each environmental control area.

4. A fully automatic sample test tube online refrigerator control system as claimed in claim 3, characterized in that: The step of confirming the control information of each environmental control area includes: The environmental control area whose environmental control mode is environmental control is recorded as area A, and the characterization index value intervals corresponding to each temperature state and each humidity state of the placed samples are extracted from the information database, and the control environment item and control method of area A are confirmed, wherein the control environment item is one or more of temperature and humidity, and the control method is one of increasing or decreasing; According to the control environment item and the environment control method, determine the control value of the control environment item, and use the control environment item and the control value of the control environment item as the control information of area A; The environmental control area where the environmental control mode is position control is recorded as area B, and the suitable adjustment area of ​​each control sample in area B is determined and used as its control information; The environmental control area whose environmental control mode is position-environment control is recorded as area C, and the control information of the A-type area and area B is used as the control information of area C, so as to confirm and obtain the control information of each environmental control area in turn.

5. A fully automatic sample test tube online refrigerator control system as claimed in claim 4, characterized in that: The step of confirming the control value of the control environment item includes: When the control environment item is temperature, the temperature control trend is counted and matched and compared with the reference temperature control trend corresponding to each set control ratio to obtain the matching control ratio. ; Extract the set temperature value of the Class A area and record it as , and extract the set control temperature range of area A from the information database, and record the upper limit and lower limit of the control temperature range as and ; When the control mode is to increase, As the control value, when the control mode is to reduce, As a control value; When the controlled environment item is humidity, the corresponding controlled value is confirmed in the same way as when the controlled environment item is temperature; When the regulated environmental item is temperature and humidity, the regulated values ​​when the regulated environmental item is temperature and when the regulated environmental item is humidity are used as the regulated values ​​of the regulated environmental item.

6. A fully automatic sample tube online refrigerator control system as claimed in claim 5, characterized in that: The statistical temperature control trend degree includes: Extract the corrected placement state consistency of each control sample in the A-class area, and select the minimum corrected placement state consistency from them , and extract the placement status difference of the control samples in the A area ; Statistical temperature control trend , , To set the reference placement state fit, To set the reference placement state match difference.

7. A fully automatic sample tube online refrigerator control system as claimed in claim 4, characterized in that: The suitable adjustment area for each control sample in the confirmed area B includes: Confirm the control information of each control sample in area B in the same way as the control information of area A, and extract the set control temperature range and set control humidity range of each storage area from the information database; The control sample whose control environment item is temperature is recorded as the temperature control sample. If the control value of the temperature control sample is within the set control temperature range of area B, area B is used as the suitable adjustment area for the temperature control sample. Otherwise, the control value of the temperature control sample is matched and compared with the set control temperature range of each storage area, and the matching storage area is used as the suitable adjustment area for the temperature control sample. The control sample whose control environment item is humidity is recorded as the humidity control sample, and the suitable control area of ​​the humidity control sample is confirmed in the same way as the confirmation method of the temperature control sample corresponding to the suitable adjustment area; The control sample whose control environment items are temperature and humidity is recorded as a comprehensive control sample. The suitable control area of ​​the comprehensive control sample is confirmed through multiple control rules, and then the suitable adjustment area of ​​each control sample in area B is obtained.

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