Microfluidic chip, microfluidic device and microdroplet control method

By using a signal transmission layer, photoresistor and first driving electrode in the microfluidic chip, the driving signal is adjusted by illumination intensity to simplify the driving structure, the problem of complex and high cost of the driving structure of the microfluidic chip is solved, and efficient Micro droplet drive and cost reduction.

CN118847242BActive Publication Date: 2025-01-17HKC CORP LTD
View PDF 2 Cites 0 Cited by

Patent Information

Application Number
CN202411329165.3
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-09-24
Publication Date
2025-01-17
Estimated Expiration
2044-09-24

AI Technical Summary

Technical Problem

The driving structure of microfluidic chips is complex and the production cost is high, which limits the application and development of microfluidic technology.

Method used

The microfluidic chip design includes a signal transmission layer, a photoresistiver and a first driving electrode is adopted to control the resistance value of the photoresistiver by adjusting the light intensity of the preset light rays, thereby forming a driving signal, simplifying the driving structure and improving the driving efficiency.

Benefits of technology

It realizes efficient driving of micro droplets, reduces preparation costs, and simplifies the driving structure of microfluidic chips, improving the application potential of the technology.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN118847242B_ABST
    Figure CN118847242B_ABST
Patent Text Reader

Abstract

The present application provides a microfluidic chip, a microfluidic device and a micro-droplet control method. The microfluidic chip includes a carrier substrate, a signal transmission layer, a photoresistor and a first driving electrode. The signal transmission layer is arranged on the carrier substrate. The signal transmission layer is used to output an initial signal. The photoresistor is connected to the signal transmission layer. The photoresistor is used to receive a preset light. The resistance of the photoresistor changes according to the light intensity of the preset light. The first driving electrode is connected to the photoresistor. The first driving electrode is used to form a driving signal according to the initial signal and the resistance of the photoresistor. The first driving electrode is used to drive the micro-droplets to move. By irradiating different areas of the microfluidic chip with preset light of different light intensities, the first driving electrodes in different areas can output different driving signals and form a driving electric field, thereby driving the micro-droplets to move. The driving structure of the microfluidic chip is relatively simple, and the driving efficiency is high, and the preparation cost is low.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The present application relates to the field of microfluidics, and in particular to a microfluidics chip, a microfluidics device and a micro-droplet control method. Background Art

[0002] Microfluidics is a technology that precisely controls and manipulates microscale fluids. It can integrate basic operating units such as sample preparation, reaction, separation, and detection in the biochemical analysis process onto a micrometer-scale chip, automatically completing the entire analysis process. Microfluidics has the advantages of low sample consumption, fast detection speed, simple operation, multifunctional integration, small size, and easy portability. It has great application potential in biology, chemistry, medicine and other fields.

[0003] In the related art, the driving structure of the microfluidic chip is relatively complex and the preparation cost is relatively high. Summary of the invention

[0004] The purpose of the present application is to provide a microfluidic chip, a microfluidic device and a micro-droplet control method to solve the technical problem that the driving structure of the microfluidic chip in the related art is relatively complex.

[0005] In a first aspect, the present application provides a microfluidic chip for controlling the movement of microdroplets, the microfluidic chip comprising:

[0006] A carrier substrate;

[0007] A signal transmission layer, disposed on the carrier substrate, and used for outputting an initial signal;

[0008] a photoresistor, connected to the signal transmission layer, the photoresistor being used to receive preset light, and the resistance value of the photoresistor changing according to the illumination intensity of the preset light; and

[0009] The first driving electrode is connected to the photoresistor, and is used to form a driving signal according to the initial signal and the resistance value of the photoresistor, and is used to drive the micro-droplet to move.

[0010] In the microfluidic chip provided by the present application, the signal transmission layer, the photoresistor and the first driving electrode are electrically connected in sequence, the signal transmission layer is used to output an initial signal, the photoresistor is used to receive a preset light, the resistance of the photoresistor changes according to the light intensity of the preset light, the first driving electrode is used to form a driving signal according to the initial signal and the resistance of the photoresistor, and drive the micro-droplets to move according to the driving signal. By irradiating different areas of the microfluidic chip with preset light of different light intensities, the first driving electrodes in different areas can output different driving signals and form a driving electric field, thereby driving the micro-droplets to move. The driving structure of the microfluidic chip is relatively simple, and the driving efficiency is high, and the preparation cost is low.

[0011] Wherein, the microfluidic chip further comprises:

[0012] An electrochromic component, arranged corresponding to the photoresistor and disposed between the photoresistor and the carrier substrate, the electrochromic component being used to transmit the initial light and form the preset light;

[0013] A thin film transistor component is disposed on the carrier substrate and between the electrochromic component and the carrier substrate. The thin film transistor component is electrically connected to the electrochromic component and is used to control the light transmittance of the electrochromic component to control the light intensity of the preset light.

[0014] Wherein, the thin film transistor assembly comprises a gate layer, a channel layer, a source layer, a drain layer and a second driving electrode, the gate layer and the channel layer are arranged correspondingly, the source layer and the drain layer are arranged at two ends of the channel layer respectively, and the second driving electrode is arranged on a side of the drain layer away from the carrier substrate;

[0015] The electrochromic component comprises an electrochromic layer, which is arranged on a side of the second driving electrode away from the drain electrode layer, and the orthographic projection of the electrochromic layer on the carrier substrate covers the orthographic projection of the photoresistor on the carrier substrate.

[0016] Wherein, the microfluidic chip further comprises a shading member, and the shading member is arranged on a side of the photoresistor away from the supporting substrate.

[0017] In a second aspect, the present application provides a microfluidic device, which includes a first light-emitting component and the microfluidic chip, wherein the first light-emitting component is disposed on a side of the supporting substrate away from the photoresistor, and the first light-emitting component is used to emit initial light.

[0018] Among them, the microfluidic device also includes a second light-emitting component, which is arranged on the side of the supporting substrate facing the photoresistor, and the second light-emitting component and the first light-emitting component are respectively arranged on both sides of the microfluidic chip. The second light-emitting component is used to emit a first light to the thin film transistor component, and control the light transmittance of the electrochromic component through the thin film transistor component.

[0019] The microfluidic chip includes a first contact layer and a second contact layer, the first contact layer covers the first driving electrode, the first contact layer and the second contact layer are spaced apart to form a receiving space, and the receiving space is used to receive micro droplets;

[0020] The microfluidic device also includes a third light-emitting component, which is arranged corresponding to the receiving space and is used to emit a second light to the thin film transistor component and control the light transmittance of the electrochromic component through the thin film transistor component.

[0021] In a third aspect, the present application provides a micro-droplet control method, which is applied to the microfluidic device, and the micro-droplet control method comprises:

[0022] Providing a signal transmission layer, a photoresistor and a first driving electrode connected in sequence, irradiating the photoresistor with the preset light, wherein the signal transmission layer is used to output an initial signal, the resistance of the photoresistor changes according to the illumination intensity of the preset light, and the first driving electrode is used to form a driving signal for driving the micro-droplet to move according to the initial signal and the resistance of the photoresistor;

[0023] The first driving electrode is controlled to drive the micro-droplet to move by adjusting the illumination intensity of the preset light.

[0024] Wherein, controlling the first driving electrode to drive the micro-droplet to move by adjusting the illumination intensity of the preset light comprises:

[0025] Providing an electrochromic component and a thin film transistor component, wherein the electrochromic component is arranged between the photoresistor and the thin film transistor component, and the thin film transistor component is electrically connected to the electrochromic component;

[0026] Irradiating an initial light on a side of the thin film transistor component away from the electrochromic component, wherein the initial light passes through the electrochromic component to form the preset light;

[0027] The light transmittance of the electrochromic component is controlled by the thin film transistor component to control the illumination intensity of the preset light.

[0028] Wherein, controlling the light transmittance of the electrochromic component by means of a thin film transistor comprises:

[0029] Controlling the thin film transistor component to be in a subthreshold state;

[0030] irradiating a first light toward the thin film transistor at a side of the thin film transistor component facing the electrochromic component;

[0031] Alternatively, the method of controlling the light transmittance of the electrochromic component by means of a thin film transistor comprises:

[0032] Controlling the thin film transistor component to be in a subthreshold state;

[0033] A second light is irradiated toward the micro-droplet from the side of the thin film transistor component. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0035] Figure 1 It is a schematic diagram of the structure of a microfluidic chip provided in the first embodiment of the present application;

[0036] Figure 2 It is a schematic structural diagram of a microfluidic device provided in the first embodiment of the present application;

[0037] Figure 3 This is a schematic diagram of the structure of a microfluidic chip provided in Embodiment 2 of the present application;

[0038] Figure 4 This is a schematic diagram of a structure in which microfluidic chips are provided with micro-droplets according to the second embodiment of the present application;

[0039] Figure 5 It is a schematic structural diagram of a microfluidic device provided in Embodiment 3 of the present application;

[0040] Figure 6 This is a schematic diagram of the structure of a microfluidic chip provided in Embodiment 4 of the present application;

[0041] Figure 7 It is a schematic diagram of the structure of a microfluidic device provided in Embodiment 5 of the present application;

[0042] Figure 8 This is a schematic structural diagram of a microfluidic device provided in Embodiment 5 of the present application, provided with micro-droplets;

[0043] Fig. 9 This is a schematic diagram of micro-droplet movement provided in Embodiment 5 of the present application;

[0044] Fig.10 This is a schematic diagram of a structure in which a microfluidic device is provided with micro-droplets provided in Embodiment 6 of the present application;

[0045] Fig.11 This is a schematic diagram of a structure in which a microfluidic device is provided with micro-droplets provided in Embodiment 7 of the present application;

[0046] Fig.12 It is a flow chart of a micro-droplet control method provided in an embodiment of the present application;

[0047] Fig.13 It is a flow chart included in S300 of a micro-droplet control method provided in an embodiment of the present application;

[0048] Fig.14 This is the process included in S330 of a micro-droplet control method provided in the embodiment of the present application. Figure 1 ;

[0049] Fig.15 This is the process included in S330 of a micro-droplet control method provided in the embodiment of the present application. Figure 2 .

[0050] Description of labels:

[0051] Microfluidic device 1000, microfluidic chip 100, first area 101, second area 102, third area 103, carrier substrate 10, signal transmission layer 21, photoresistor 22, first drive electrode 23, first contact layer 30, electrochromic component 40, electrochromic layer 41, color-changing common electrode 42, thin film transistor component 50, gate layer 51, channel layer 52, source layer 53, drain layer 54, second drive electrode 55, gate insulating layer 61, first insulating layer 62, second insulating layer 63, shading member 70, second contact layer 80, common electrode layer 90, backlight assembly 200, first light-emitting assembly 300, second light-emitting assembly 400, third light-emitting assembly 500, light-emitting member 501, microdroplet 600. DETAILED DESCRIPTION

[0052] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0053] It should be noted that the terms "first", "second", etc. in the specification and claims of this application and the above drawings are used to distinguish different objects rather than to describe a specific order. In addition, the terms "including" and "having" and any variations thereof are intended to cover non-exclusive inclusions.

[0054] In this specification, for the sake of convenience, the words and phrases indicating the orientation or positional relationship such as "middle", "upper", "lower", "front", "back", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like are used to illustrate the positional relationship of the constituent elements with reference to the drawings. This is only for the convenience of describing this specification and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as a limitation of the present disclosure. The positional relationship of the constituent elements is appropriately changed according to the orientation of the constituent elements being described. Therefore, it is not limited to the words and phrases described in the specification, and can be appropriately replaced according to the circumstances.

[0055] In this specification, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection, or an electrical connection; it can be a direct connection, or an indirect connection through an intermediate, or the internal communication of two elements. For ordinary technicians in this field, the meanings of the above terms in this disclosure can be understood according to the circumstances.

[0056] Microfluidics is a technology that precisely controls and manipulates microscale fluids. It can integrate basic operating units such as sample preparation, reaction, separation, and detection in the biochemical analysis process onto a micrometer-scale chip, automatically completing the entire analysis process. Microfluidics has the advantages of low sample consumption, fast detection speed, simple operation, multifunctional integration, small size, and easy portability. It has great application potential in biology, chemistry, medicine and other fields.

[0057] Among them, digital microfluidic chips generally drive droplets to move through the dielectric wetting effect, that is, by applying voltage to the electrodes to change the contact angle of the droplets, thereby driving the droplets to move. In related technologies, the driving structure of microfluidic chips is relatively complex and the preparation cost is relatively high.

[0058] Please refer to Figure 1It should be noted that the solid lines and arrows in the accompanying drawings are schematic diagrams of light and should not be understood as limitations on the present application. The present application provides a microfluidic chip 100, which is used to control the movement of microdroplets 600. The microfluidic chip 100 includes a carrier substrate 10, a signal transmission layer 21, a photoresistor 22, and a first drive electrode 23. The signal transmission layer 21 is arranged on the carrier substrate 10, and the signal transmission layer 21 is used to output an initial signal. The photoresistor 22 is connected to the signal transmission layer 21, and the photoresistor 22 is used to receive a preset light, and the resistance of the photoresistor 22 changes according to the light intensity of the preset light. The first drive electrode 23 is connected to the photoresistor 22, and the first drive electrode 23 is used to form a drive signal according to the initial signal and the resistance of the photoresistor 22, and the first drive electrode 23 is used to drive the microdroplet 600 to move.

[0059] Specifically, in this embodiment, the microfluidic chip 100 also includes a first contact layer 30, which covers the signal transmission layer 21, the photoresistor 22 and the first driving electrode 23, wherein the first contact layer 30 includes a first dielectric layer and a first hydrophobic layer, the first hydrophobic layer is arranged on the side of the first dielectric layer away from the supporting substrate 10, and the first hydrophobic layer is used to carry the microdroplets 600.

[0060] It should be noted that the microfluidic chip 100 in the present application drives the micro-droplet 600 to move by the dielectric wetting effect. Specifically, when a voltage is applied to the first signal transmission layer 21 and the first drive electrode 23 under the dielectric layer, the wetting characteristics between the dielectric layer and the micro-droplet 600 attached to its surface will change. This change causes the contact angle between the micro-droplet 600 and the surface of the hydrophobic layer to change, causing the micro-droplet 600 to produce asymmetric deformation. This asymmetric deformation will produce a hydrostatic pressure difference inside the micro-liquid. When this pressure difference is large enough, the micro-droplet 600 can be driven from a static state and move continuously along the driving direction of the first drive electrode 23. In addition, the moving direction of the micro-droplet 600 is opposite to the direction of the electric field.

[0061] Specifically, in this embodiment, the carrier substrate 10 can be used to carry structural parts such as the signal transmission layer 21, the photoresistor 22 and the first drive electrode 23. Optionally, in this embodiment, the material of the carrier substrate 10 is glass material, and the carrier substrate 10 can be used to transmit visible light. In other embodiments, the carrier substrate 10 can also be other light-transmitting materials, which is not limited in this application. The signal transmission layer 21 is used to electrically connect the controller of the microfluidic chip 100, and to receive and output the initial signal to the photoresistor 22 and the first drive electrode 23. Optionally, the material of the signal transmission layer 21 includes but is not limited to indium tin oxide (ITO), the material of the drive signal line includes but is not limited to metal copper, aluminum or other conductive materials, and the photoresistor 22 includes but is not limited to cadmium sulfide photoresistor (CdS photoresistor), lead sulfide photoresistor (PbS photoresistor) or other types of photoresistors, which is not limited in this application.

[0062] The microfluidic chip 100 includes a photoresistor 22 disposed between the signal transmission layer 21 and the first driving electrode 23 and connected to the signal transmission layer 21 and the first driving electrode 23 respectively. The photoresistor 22 can be used to receive preset light, and the resistance value of the photoresistor 22 changes according to the light intensity of the preset light.

[0063] For example, when the micro-droplet 600 needs to move from the first area 101 to the second area 102 of the microfluidic chip 100, the first area 101 and the second area 102 both include a photoresistor 22 and a first driving electrode 23, and the photoresistor 22 and the first driving electrode 23 of the first area 101 and the photoresistor 22 and the first driving electrode 23 of the second area 102 are relatively independent and spaced apart. In the first area 101, the preset light intensity is enhanced, and the resistance of the photoresistor 22 in the first area 101 decreases, so that the voltage drop of the initial signal through the photoresistor 22 is reduced, thereby increasing the voltage of the driving signal on the first driving electrode 23 in the first area 101. At the same time, the preset light intensity is weakened in the second area 102, and the resistance of the photoresistor 22 in the second area 102 increases, so that the voltage drop of the initial signal through the photoresistor 22 is increased, thereby reducing the voltage of the driving signal on the first driving electrode 23 in the first area 101, so that the driving signal of the first driving electrode 23 in the first area 101 and the driving signal of the first driving electrode 23 in the second area 102 form a voltage difference, thereby forming a driving electric field to drive the micro-droplet 600 to move. It should be noted that the moving direction of the microdroplet 600 is opposite to the direction of the electric field. If the microdroplet 600 needs to move from the first area 101 to the second area 102, the direction of the electric field is from the second area 102 to the first area 101. In other words, the initial signal and the driving signal are negative high voltage signals.

[0064] It should be noted that the present application does not impose any specific restrictions on how the illumination intensity of the preset light changes, which will be described in detail later in conjunction with specific embodiments and should not be construed as a limitation on the present application.

[0065] Please refer to Figure 2 For example, in one embodiment, the microfluidic chip 100 can be matched with the backlight assembly 200. The carrier substrate 10 is a transparent substrate, and the backlight assembly 200 is disposed on one side of the carrier substrate 10. The backlight assembly 200 is used to emit a preset light toward the carrier substrate 10, and the preset light passes through the carrier substrate 10 and irradiates the photoresistor 22. The backlight assembly 200 can be used to adjust the light intensity change of the preset light in each area to control the resistance value of the photoresistor 22 in each area on the microfluidic chip 100, and then control the driving signal of the first driving electrode 23 in each area on the microfluidic chip 100, so as to realize the movement control of the micro droplets 600 on the microfluidic chip 100.

[0066] In the microfluidic chip 100 provided by the present application, the signal transmission layer 21, the photoresistor 22 and the first driving electrode 23 are electrically connected in sequence, the signal transmission layer 21 is used to output the initial signal, the photoresistor 22 is used to receive the preset light, the resistance of the photoresistor 22 changes according to the light intensity of the preset light, and the first driving electrode 23 is used to form a driving signal according to the initial signal and the resistance of the photoresistor 22, and drive the micro-droplet 600 to move according to the driving signal. According to the preset light of different light intensities irradiated in different areas of the microfluidic chip 100, the first driving electrode 23 in different areas can output different driving signals and form a driving electric field, thereby driving the micro-droplet 600 to move. The driving structure of the microfluidic chip 100 is relatively simple, and the driving efficiency is high, and the preparation cost is low.

[0067] At present, due to the maturity of thin-film transistor (TFT) backplane technology and low preparation cost, the microfluidic chip 100 based on thin-film transistor (TFT) drive is increasingly valued by the market. However, the dielectric wetting effect driving voltage is generally high, sometimes needing to reach 60V-90V or even hundreds of volts. This voltage is difficult for existing thin-film transistor devices to withstand, limiting the application of thin-film transistor technology in the microfluidic chip 100.

[0068] The microfluidic chip 100 of the present application can be combined with a thin film driven transistor device structure to solve the technical problem in the related art that the thin film transistor driven backplane technology is difficult to apply to the microfluidic field.

[0069] Please refer to Figure 3Specifically, the microfluidic chip 100 of the present application includes an electrochromic component 40 and a thin film transistor component 50. The electrochromic component 40 is arranged corresponding to the photoresistor 22 and is arranged between the photoresistor 22 and the carrier substrate 10. The electrochromic component 40 is used to transmit the initial light and form a preset light. The thin film transistor component 50 is arranged on the carrier substrate 10 and is arranged between the electrochromic component 40 and the carrier substrate 10. The thin film transistor component 50 is electrically connected to the electrochromic component 40. The thin film transistor component 50 is used to control the light transmittance of the electrochromic component 40 to control the light intensity of the preset light.

[0070] The electrochromic component 40 is disposed on the side of the photoresistor 22 facing the carrier substrate 10. When the initial light is irradiated from the side of the carrier substrate 10, the initial light will pass through the carrier substrate 10 and first pass through the electrochromic component 40 to form a preset light, which is then irradiated onto the photoresistor 22. It should be noted that the electrochromic component 40 can absorb or block a portion of the initial light, thereby achieving the purpose of adjusting the intensity of the preset light. Further, when powered on, the electrochromic component 40 can change its own color and transmittance according to the provided electrical signal to adjust the amount of the blocked initial light, thereby achieving the purpose of adjusting the intensity of the preset light. For example, when the electrochromic component 40 receives an electrical signal and deepens its color, the light transmittance of the electrochromic component 40 decreases, and the amount of initial light blocked increases, thereby reducing the light intensity of the preset light passing through the electrochromic component 40; when the electrochromic component 40 receives an electrical signal and dilutes its color and increases its transparency, the light transmittance of the electrochromic component 40 increases, and the amount of initial light blocked decreases, thereby enhancing the light intensity of the preset light passing through the electrochromic component 40.

[0071] The thin film transistor component 50 of the present application is electrically connected to the electrochromic component 40, and the thin film transistor component 50 is used to control the light transmittance of the electrochromic component 40 to control the light intensity of the preset light. It should be noted that in this embodiment, the initial state of the electrochromic component 40 is the light shielding state, and the thin film transistor component 50 supplies electricity to the electrochromic component 40 to control the light transmittance of the electrochromic component 40 to increase and enter the light transmitting state.

[0072] Please refer to Figure 3 and Figure 4For example, when the micro-droplet 600 needs to move from the first area 101 to the second area 102 of the microfluidic chip 100. The first area 101 and the second area 102 both include a photoresistor 22, a first driving electrode 23, an electrochromic component 40 and a thin film transistor component 50, and the photoresistor 22, the first driving electrode 23, the electrochromic component 40 and the thin film transistor component 50 of the first area 101 and the photoresistor 22, the first driving electrode 23, the electrochromic component 40 and the thin film transistor component 50 of the second area 102 are relatively spaced and independently arranged. In the first area 101, the thin film transistor controls the light transmittance of the electrochromic component 40 to increase so that the light intensity of the preset light is enhanced, and the resistance of the photoresistor 22 in the first area 101 decreases so that the voltage drop of the initial signal through the photoresistor 22 is reduced, thereby increasing the voltage of the driving signal on the first driving electrode 23 in the first area 101. At the same time, in the second area 102, the thin film transistor controls the light transmittance of the electrochromic component 40 to decrease so that the light intensity of the preset light is weakened, and the resistance of the photoresistor 22 in the second area 102 increases so that the voltage drop of the initial signal through the photoresistor 22 is increased, thereby reducing the voltage of the driving signal on the first driving electrode 23 in the second area 102, so that the driving signal of the first driving electrode 23 in the first area 101 and the driving signal of the first driving electrode 23 in the second area 102 form a voltage difference, thereby forming a driving electric field to drive the micro-droplets 600 to move.

[0073] It should be noted that the present application does not impose any specific restrictions on how the thin film transistor component 50 controls the light transmittance of the electrochromic component 40. In this embodiment, similar to the display panel structure in the related art, a scanning signal and a data signal can be input to multiple thin film transistor components 50 in different areas of the microfluidic chip 100 to drive the multiple thin film transistor components 50 to respectively control the light transmittance of the multiple electrochromic components 40, so as to realize the output of different driving signals by the multiple first driving electrodes 23, thereby controlling the movement of the micro droplets 600 on the microfluidic chip 100.

[0074] Please refer to Figures 3 to 5For example, in one embodiment, the microfluidic chip 100 can be matched with the first light-emitting component 300. The carrier substrate 10 is a transparent substrate, and the first light-emitting component 300 is arranged on one side of the carrier substrate 10. The first light-emitting component 300 is used to emit initial light toward the carrier substrate 10. The initial light passes through the carrier substrate 10 and irradiates the electrochromic component 40, and forms a preset light after passing through the electrochromic component 40. Among them, the illumination intensity of the initial light emitted by each area of ​​the first light-emitting component 300 is the same. In other embodiments, the initial light can also be ambient light, such as outdoor sunlight. For example, the user can place the microfluidic chip 100 of the present application outdoors, and the carrier substrate 10 faces the sun or other luminous objects. The initial light emitted by the sun or other luminous objects cooperates with the structural devices inside the microfluidic chip 100 to achieve control of the microdroplets 600.

[0075] In the microfluidic chip 100 provided in the present application, the electrochromic component 40 is arranged on the supporting substrate 10 and is used to receive the initial light irradiated from the side of the supporting substrate 10. The electrochromic component 40 can also be used to transmit the initial light and form a preset light. The thin film transistor component 50 is electrically connected to the electrochromic component 40 and is used to control the light transmittance of the electrochromic component 40. The signal transmission layer 21, the photoresistor 22 and the first driving electrode 23 are electrically connected in sequence. The photoresistor 22 is used to receive the preset light. The resistance of the photoresistor 22 changes according to the light intensity of the preset light. The first driving electrode 23 is used to form a driving signal according to the initial signal of the signal transmission layer 21 and the resistance of the photoresistor 22. By controlling the electrochromic component 40 according to the multiple thin film transistors of the microfluidic chip 100, the multiple first driving electrodes 23 can be controlled to drive the microdroplets 600 to move, that is, the driving signal of the microdroplet 600 is provided through the signal transmission layer 21, the photoresistor 22 and the first driving electrode 23. The photoresistor 22 generally has a high tolerance to high voltage. The signal transmission layer 21, the photoresistor 22 and the first driving electrode 23 can provide a larger driving voltage. The thin film transistor component 50 only needs to provide a smaller driving voltage to drive the electrochromic component 40, which is convenient for effectively applying the thin film transistor component 50 in the field of microfluidics.

[0076] Please refer to Figure 3 Furthermore, the thin film transistor assembly 50 includes a gate layer 51, a channel layer 52, a source layer 53, a drain layer 54 and a second driving electrode 55. The gate layer 51 and the channel layer 52 are arranged correspondingly, the source layer 53 and the drain layer 54 are respectively arranged at two ends of the channel layer 52, and the second driving electrode 55 is arranged on the side of the drain layer 54 away from the supporting substrate 10.

[0077] Furthermore, the microfluidic chip 100 also includes a gate insulating layer 61, a first insulating layer 62, and a second insulating layer 63. The gate insulating layer 61 covers the gate layer 51 of the thin film transistor component 50, and the channel layer 52, the source layer 53, and the drain layer 54 are all arranged on the gate insulating layer 61. The gate insulating layer 61 can be used to insulate the gate layer 51 and other metal layer structures, and prevent the gate layer 51 from being corroded by water vapor in the external environment, thereby extending the service life of the electrode metal. Optionally, the material of the gate insulating layer 61 includes but is not limited to silicon nitride (SiNx), silicon oxide (SiOx) or other insulating materials.

[0078] Similarly, the first insulating layer 62 covers the channel layer 52, the source layer 53 and the drain layer 54, and the second driving electrode 55 and the electrochromic component 40 are all arranged on the first insulating layer 62. The first insulating layer 62 can be used to insulate the source layer 53, the drain layer 54 and other metal layer structures, and prevent the second driving electrode 55 and the electrochromic component 40 from being corroded by water vapor in the external environment, thereby extending the service life of the electrode metal. Optionally, the material of the first insulating layer 62 includes but is not limited to silicon nitride (SiNx), silicon oxide (SiOx), polyimide (PI), polymethyl methacrylate (PMMA) or other insulating materials.

[0079] Similarly, the second insulating layer 63 covers the second driving electrode 55 and the electrochromic component 40, and the driving transmission layer, the photoresistor 22 and the first driving electrode 23 are all arranged on the second insulating layer 63. The second insulating layer 63 can be used to insulate the driving transmission layer, the first driving electrode 23 and other metal layer structures, and prevent the driving transmission layer and the first driving electrode 23 from being corroded by water vapor in the external environment, thereby extending the service life of the electrode metal. Optionally, the material of the second insulating layer 63 includes but is not limited to silicon nitride (SiNx), silicon oxide (SiOx), polyimide (PI), polymethyl methacrylate (PMMA) or other insulating materials.

[0080] Furthermore, the electrochromic component 40 includes an electrochromic layer 41 and a color-changing common electrode 42, wherein the electrochromic layer 41 is disposed on a side of the second driving electrode 55 away from the drain electrode layer 54, and the color-changing common electrode 42 is disposed on a side of the electrochromic layer 41 away from the second driving electrode 55. The electrochromic common electrode 42 is used to form a voltage difference with the second driving electrode 55, so that the electrochromic layer 41 changes color and the transmittance changes.

[0081] Furthermore, the orthographic projection of the electrochromic layer 41 on the carrier substrate 10 covers the orthographic projection of the photoresistor 22 on the carrier substrate 10 .

[0082] In other words, the area of ​​the electrochromic layer 41 is larger than the area of ​​the photoresistor 22, that is, when the initial light is irradiated from the side of the supporting substrate 10 toward the electrochromic layer 41, the initial light will all pass through the electrochromic layer 41 and control the initial light through the change in the transmittance of the electrochromic layer 41 to form a preset light with a specific light intensity, which can prevent the initial light from directly irradiating the photoresistor 22 and affecting the control accuracy of the resistance value of the photoresistor 22.

[0083] Please refer to Figure 6 Furthermore, the microfluidic chip 100 further includes a light shielding member 70 , which is disposed on a side of the photoresistor 22 away from the supporting substrate 10 .

[0084] Optionally, the material of the channel layer 52 in the thin film transistor component 50 includes amorphous silicon (A-Si), polycrystalline silicon and other materials. When the channel layer 52 is illuminated, it is easy to produce photogenerated carriers, and the photogenerated carriers can affect the conduction performance of the thin film transistor component 50. The more photogenerated carriers there are, the better the conduction effect of the thin film transistor component 50. In other words, the thin film transistor component 50 is greatly affected by light, that is, when the channel layer 52 of the thin film transistor component 50 is illuminated with high intensity, the photogenerated carriers are more, and the opening degree of the thin film transistor component 50 is greater. When the channel layer 52 of the thin film transistor component 50 is illuminated with low intensity, the photogenerated carriers are less, and the opening degree of the thin film transistor component 50 is less.

[0085] Please refer to Figure 6 and Figure 7 In one embodiment, the microfluidic chip 100 can be matched with the second light-emitting component 400. The second light-emitting component 400 is arranged on the side of the carrier substrate 10 facing the photoresistor 22, and the second light-emitting component 400 and the first light-emitting component 300 are respectively arranged on both sides of the microfluidic chip 100. The second light-emitting component 400 is used to emit the first light to the thin film transistor component 50, and the light transmittance of the electrochromic component 40 is controlled by the thin film transistor component 50.

[0086] Specifically, the second light emitting component 400 can be used to adjust the illumination intensity of the first light, and control the conduction of the thin film transistor component 50 by the illumination intensity of the first light, and control the light transmittance of the electrochromic component 40 by the thin film transistor component 50. It should be noted that in this embodiment, the initial state of the electrochromic component 40 is the light-transmitting state, and the thin film transistor component 50 supplies electricity to the electrochromic component 40 to control the light transmittance of the electrochromic component 40 to decrease and gradually enter the light-shielding state.

[0087] For example, when the micro droplet 600 needs to move from the first area 101 to the second area 102 of the microfluidic chip 100, the gate signal is first input to all the thin film transistor components 50. At this time, there is no need to input a signal to a specific thin film transistor component 50, so there is no need for gate drive module control, and the same signal can be directly input to the gate layer 51 of all thin film transistor components 50 at the same time. The magnitude of the gate signal voltage is controlled so that all thin film transistor components 50 are in a subthreshold state, that is, all thin film transistor components 50 are in a state of being about to be turned on but not turned on. At this time, the thin film transistor components 50 will enter the open state after being exposed to sufficient light. The microfluidic chip 100 is irradiated with a first light through the second light-emitting component 400. The micro-droplets 600 in the first area 101 are arranged between the thin-film transistor component 50 and the second light-emitting component 400. When the first light passes through the micro-droplets 600, it will be affected by the micro-droplets 600 (including but not limited to absorption, refraction, and reflection), which will cause the illumination intensity of the first light emitted from the first area 101 to the channel layer 52 of the thin-film transistor component 50 to be lowered, thereby causing the opening degree of the thin-film transistor component 50 in the first area 101 to be small when in the open state. At this time, the light transmittance of the electrochromic component 40 is relatively high, and the photoresistor 22 in the first area 101 receives the preset light with a relatively high light intensity and reduces its own resistance, thereby causing the first area 101 to be The voltage of the first driving electrode 23 in the second area 102 is relatively high. At the same time, the illumination intensity of the first light irradiated to the channel layer 52 of the thin film transistor component 50 in the second area 102 is relatively high, so that the opening degree of the thin film transistor component 50 in the second area 102 is large when it is in the open state. At this time, the transmittance of the electrochromic component 40 is relatively low, and the photoresistor 22 in the second area 102 receives the preset light with lower light intensity and increases its own resistance, thereby making the voltage of the first driving electrode 23 in the second area 102 relatively low, so that the driving signal of the first driving electrode 23 in the first area 101 and the driving signal of the first driving electrode 23 in the second area 102 form a voltage difference, thereby forming a driving electric field to drive the micro-droplets 600 to move.

[0088] It should be noted that, in the above embodiment, only the first area 101 where the microfluidic chip 100 is located and the second area 102 to which it needs to move are used for schematic illustration, and only the movement of the microdroplets 600 in the microfluidic chip 100 can be controlled, and the movement of the microdroplets 600 in the microfluidic chip 100 to a preset direction cannot be controlled. Further, in one embodiment, the microfluidic chip 100 further includes a third area 103, such as Figure 8As shown, the third area 103 and the second area 102 are respectively located on both sides of the first area 101. The second light emitting component 400 emits a first light with a relatively strong light to the second area 102 of the microfluidic chip 100, and emits a first light with a relatively weak light to the third area 103 of the microfluidic chip 100, so that the opening degree of the thin film transistor component 50 in the second area 102 is greater than the opening degree of the thin film crystal component in the third area 103, the light transmittance of the electrochromic component 40 in the second area 102 is lower than the light transmittance of the electrochromic component 40 in the third area 103, and the resistance value of the photoresistor 22 in the second area 102 is greater than the resistance value of the photoresistor 22 in the third area 103, so that the light transmittance of the third area 103 is greater than the light transmittance of the photoresistor 22 in the second area 102. The driving signal of the first driving electrode 23 is smaller than the driving signal of the first driving electrode 23 in the third area 103, thereby making the voltage difference between the driving signal of the first driving electrode 23 in the first area 101 and the driving signal of the first driving electrode 23 in the second area 102 greater than the voltage difference between the driving signal of the first driving electrode 23 in the first area 101 and the driving signal of the first driving electrode 23 in the third area 103, so that the micro-droplet 600 is subjected to a larger driving force to move toward the second area 102, thereby preventing the micro-droplet 600 from moving toward the third area 103, thereby achieving precise control of the moving direction of the micro-droplet 600.

[0089] The light shielding member 70 is used to shield the first light emitted by the second light emitting component 400, so as to prevent the first light from affecting the photoresistor 22, so that the photoresistor 22 only receives the preset light and controls its resistance according to the light intensity of the preset light. The gate layer 51 can be used to shield the initial light from irradiating the channel layer 52, so as to prevent the initial light from affecting the channel layer 52, so that the channel layer 52 can only generate photogenerated carriers according to the first light.

[0090] It should be noted that the second area 102 refers to an area adjacent to the position of the micro-droplet 600 and the area to which the micro-droplet 600 needs to move. In other words, there can be multiple second areas 102 to enable the micro-droplet 600 to achieve continuous movement. Specifically, the intensity of multiple light-emitting components on the second light-emitting component 400 can be set to strong light in sequence to correspond to multiple second areas 102 to achieve continuous movement of the micro-droplet 600. Fig. 9 As shown, the dotted line is the moving path of the micro-droplet 600. Along the moving path, the multiple light-emitting components corresponding to the second light-emitting component 400 can be set to strong light in turn, and the other light-emitting components can be set to emit weak light to control the movement of the micro-droplet 600 along the moving path.

[0091] Please refer to Figure 2The present application also provides a microfluidic device 1000, which includes a backlight assembly 200 and a microfluidic chip 100. The backlight assembly 200 can be used to directly emit preset light, and the backlight assembly 200 can be used to cooperate with the microfluidic chip 100 to move the microdroplets 600 on the microfluidic chip 100.

[0092] Please refer to Figure 5 In one embodiment, the microfluidic device 1000 includes a first light-emitting component 300 and a microfluidic chip 100. The first light-emitting component 300 is the same structural component as the first light-emitting component 300 described above, and the first light-emitting component 300 is disposed on a side of the carrier substrate 10 away from the photoresistor 22, and the first light-emitting component 300 is used to emit initial light.

[0093] The first light-emitting component 300 is used to cooperate with the microfluidic chip 100 and provide initial light, so that the electrochromic component 40 can receive the initial light and control the intensity of the preset light transmitted according to the change of its own transmittance, thereby realizing subsequent control.

[0094] Please refer to Figure 7 In one embodiment, the microfluidic device 1000 further includes a second light-emitting component 400, which is disposed on a side of the carrier substrate 10 facing the photoresistor 22, and the second light-emitting component 400 and the first light-emitting component 300 are respectively disposed on two sides of the microfluidic chip 100, and the second light-emitting component 400 is used to emit a first light to the thin film transistor component 50, and control the light transmittance of the electrochromic component 40 through the thin film transistor component 50.

[0095] Specifically, the second light-emitting component 400 can be used to adjust the light intensity of the first light, and control the conduction of the thin film transistor component 50 through the light intensity of the first light, and control the light transmittance of the electrochromic component 40 through the thin film transistor component 50.

[0096] Please refer to Fig.10 In one embodiment, the microfluidic chip 100 further includes a second contact layer 80 , and the second contact layer 80 and the first contact layer 30 are spaced apart to form a receiving space, and the receiving space is used to receive the micro-droplets 600 .

[0097] The microfluidic device 1000 further includes a third light emitting component 500 , which is disposed corresponding to the receiving space and is used to emit a second light to the thin film transistor component 50 , and control the light transmittance of the electrochromic component 40 through the thin film transistor component 50 .

[0098] It should be noted that, in this embodiment, the initial state of the electrochromic component 40 is a light-transmitting state, and the thin film transistor component 50 supplies power to the electrochromic component 40 to control the light transmittance of the electrochromic component 40 to decrease and gradually enter a light-shielding state.

[0099] For example, when the micro droplet 600 needs to move from the first area 101 to the second area 102 of the microfluidic chip 100, the gate signal is first input to all the thin film transistor components 50. At this time, there is no need to input a signal to a specific thin film transistor component 50, so there is no need for gate drive module control, and the same signal can be directly input to the gate layer 51 of all thin film transistor components 50 at the same time. The magnitude of the gate signal voltage is controlled so that all thin film transistor components 50 are in a subthreshold state, that is, all thin film transistor components 50 are in a state of being about to be turned on but not turned on. At this time, the thin film transistor components 50 will enter the open state after being exposed to sufficient light. The microfluidic chip 100 is irradiated with a second light by the third light emitting component 500, and the micro droplet 600 is in the first area 101. When the second light passes through the micro droplet 600, it will be affected by the micro droplet 600 (including but not limited to absorption, refraction, and reflection), which will reduce the illumination intensity of the second light incident on the channel layer 52 of the thin film transistor component 50 in the first area 101, thereby reducing the degree of opening of the thin film transistor component 50 in the first area 101 when it is in an open state. At this time, the light transmittance of the electrochromic component 40 is high, and the photoresistor 22 in the first area 101 receives the preset light with a high light intensity and reduces its own resistance, thereby reducing the electric field of the first driving electrode 23 in the first area 101. The voltage is higher. At the same time, the illumination intensity of the second light irradiated to the channel layer 52 of the thin film transistor component 50 in the second area 102 is higher, so that the opening degree of the thin film transistor component 50 in the second area 102 is large when it is in the open state. At this time, the transmittance of the electrochromic component 40 is lower, and the photoresistor 22 in the second area 102 receives the preset light with lower light intensity and increases its own resistance, so that the voltage of the first driving electrode 23 in the second area 102 is lower, so that the driving signal of the first driving electrode 23 in the first area 101 and the driving signal of the first driving electrode 23 in the second area 102 form a voltage difference, thereby forming a driving electric field to drive the micro-droplet 600 to move.

[0100] Furthermore, the microfluidic chip 100 further includes a common electrode layer 90, which is disposed on the side of the second contact layer 80 away from the carrier substrate 10, and the common electrode layer 90 can be used to provide a common signal. In addition, the common electrode layer 90 can be used to reflect the second light, so that the second light emitted from the second area 102 to the channel layer 52 of the thin film transistor assembly 50 has a higher illumination intensity.

[0101] It should be noted that, in this embodiment, the area on the microfluidic chip 100 close to the microdroplet 600 and located between the microdroplet 600 and the third light-emitting component 500 is the second area 102. In other words, when the third light-emitting component 500 is arranged on the side of the microfluidic chip 100, the microdroplet 600 moves toward the light-emitting portion of the third light-emitting component 500.

[0102] In one embodiment, see Fig.11 The third light-emitting component 500 may include a plurality of light-emitting elements 501, and the plurality of light-emitting elements 501 are respectively arranged around the periphery of the microfluidic chip 100. When the micro-droplet 600 needs to move in a certain direction, the corresponding light-emitting element 501 can be controlled to emit light.

[0103] Please refer to Fig.12 The present application also provides a micro-droplet 600 control method, which is applied to the microfluidic device 1000. The micro-droplet 600 control method includes step S100 and step S300. The detailed description of step S100 and step S300 is as follows.

[0104] S100: Provide a signal transmission layer 21, a photoresistor 22 and a first driving electrode 23 connected in sequence, and irradiate the photoresistor 22 with a preset light, wherein the signal transmission layer 21 is used to output an initial signal, the resistance of the photoresistor 22 changes according to the light intensity of the preset light, and the first driving electrode 23 is used to form a driving signal for driving the micro-droplet 600 to move according to the initial signal and the resistance of the photoresistor 22.

[0105] S300: Controlling the first driving electrode 23 to drive the micro-droplet 600 to move by adjusting the illumination intensity of the preset light.

[0106] It should be noted that the specific details and feasible implementation methods of step S100 and step S300 have been described in detail above and will not be repeated here.

[0107] In the micro-droplet 600 control method provided in the present application, by irradiating different areas of the microfluidic chip 100 with preset light of different light intensities, the first driving electrodes 23 in different areas can output different driving signals and form a driving electric field, thereby driving the micro-droplet 600 to move. The micro-droplet 600 control method is relatively simple and has high driving efficiency.

[0108] Please refer to Fig.13 In one embodiment, step S300 controls the first driving electrode 23 to drive the micro-droplet 600 to move by adjusting the illumination intensity of the preset light, including step S310, step S320 and step S330. The detailed description of step S310, step S320 and step S330 is as follows.

[0109] S310 : providing an electrochromic component 40 and a thin film transistor component 50 , wherein the electrochromic component 40 is disposed between the photoresistor 22 and the thin film transistor component, and the thin film transistor component 50 is electrically connected to the electrochromic component 40 .

[0110] S320: irradiating the initial light on the side of the thin film transistor component 50 away from the electrochromic component 40 , and the initial light passes through the electrochromic component 40 to form a preset light.

[0111] S330: Control the light transmittance of the electrochromic component 40 through the thin film transistor component 50 to control the illumination intensity of the preset light.

[0112] It should be noted that the specific details and feasible implementation methods of step S310, step S320 and step S330 have been described in detail above and will not be repeated here.

[0113] In the micro-droplet 600 control method provided in the present application, the electrochromic component 40 can be controlled by multiple thin film transistors of the microfluidic chip 100 to control multiple first driving electrodes 23 to drive the micro-droplet 600 to move, that is, the driving signal of the micro-droplet 600 is provided by the signal transmission layer 21, the photoresistor 22 and the first driving electrode 23. The photoresistor 22 generally has a high tolerance to high voltage. The signal transmission layer 21, the photoresistor 22 and the first driving electrode 23 can provide a larger driving voltage. The thin film transistor component 50 only needs to provide a smaller driving voltage to drive the electrochromic component 40, which is convenient for the thin film transistor component 50 to be effectively used in the field of microfluidics.

[0114] Please refer to Fig.14 In one embodiment, step S330 controls the light transmittance of the electrochromic component 40 through a thin film transistor, including step S331 and step S332. Step S331 and step S332 are described in detail as follows.

[0115] S331: Control the thin film transistor component 50 to be in a subthreshold state.

[0116] Specifically, a gate signal is first input to all thin film transistor components 50. At this time, there is no need to input a signal to a specific thin film transistor component 50, so there is no need for gate drive module control. The same signal can be directly input to the gate layer 51 of all thin film transistor components 50 at the same time. The magnitude of the gate signal voltage is controlled so that all thin film transistor components 50 are in a subthreshold state, that is, all thin film transistor components 50 are in a state of being about to be turned on but not turned on. At this time, the thin film transistor components 50 will enter the turned-on state after being exposed to sufficient light.

[0117] S332: irradiating a first light toward the thin film transistor at a side of the thin film transistor component 50 facing the electrochromic component 40 .

[0118] Specifically, the second light emitting component 400 emits the first light to the thin film transistor component 50, and the thin film transistor component 50 controls the light transmittance of the electrochromic component 40. The cooperation process between the second light emitting component 400 and the microfluidic chip 100 has been described in detail above and will not be repeated here.

[0119] Please refer to Fig.15 In one embodiment, step S330 controls the light transmittance of the electrochromic component 40 through a thin film transistor, including step S333 and step S334. The detailed description of step S333 and step S334 is as follows.

[0120] S333: Control the thin film transistor component 50 to be in a subthreshold state.

[0121] S334 : irradiating the second light toward the micro-droplet 600 from the side of the thin film transistor component 50 .

[0122] Specifically, the third light emitting component 500 emits the second light to the thin film transistor component 50, and the thin film transistor component 50 controls the light transmittance of the electrochromic component 40. The cooperation process between the third light emitting component 500 and the microfluidic chip 100 has been described in detail above and will not be repeated here.

[0123] Mentioning "embodiment" and "implementation method" in this application means that the specific features, structures or characteristics described in conjunction with the embodiment may be included in at least one embodiment of the present application. The appearance of the phrases in various places in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment that is mutually exclusive with other embodiments. It is explicitly and implicitly understood by those skilled in the art that the embodiments described in this application can be combined with other embodiments. In addition, it should also be understood that the features, structures or characteristics described in the various embodiments of the present application can be arbitrarily combined to form another embodiment that does not deviate from the spirit and scope of the technical solution of the present application, provided that there is no contradiction between them.

[0124] The above is part of the implementation methods of the present application. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present application. These improvements and modifications are also considered to be within the scope of protection of the present application.

Claims

1. A micro-droplet control method, characterized in that: The micro-droplet control method comprises: A microfluidic chip is provided, the microfluidic chip comprising a carrier substrate, a signal transmission layer, a photoresistor, a first driving electrode, an electrochromic component, a thin film transistor component and a shading member, the signal transmission layer being arranged on the carrier substrate, the signal transmission layer being used to output an initial signal, the photoresistor being connected to the signal transmission layer, the photoresistor being used to receive a preset light, the resistance value of the photoresistor changing according to the light intensity of the preset light, the first driving electrode being connected to the photoresistor, the first driving electrode being used to form a driving signal according to the initial signal and the resistance value of the photoresistor, the first driving electrode being used to drive a micro droplet to move, the electrochromic component being arranged corresponding to the photoresistor and being arranged between the photoresistor and the carrier substrate, the electrochromic component being used to transmit the initial light and form the preset light, the thin film transistor component being arranged on the carrier substrate and being arranged between the electrochromic component and the carrier substrate, the thin film transistor component being electrically connected to the electrochromic component, the thin film transistor component being used to control the light transmittance of the electrochromic component to control the The illumination intensity of the preset light, the microfluidic chip also includes a shading member, the shading member is arranged on the side of the photoresistor away from the supporting substrate, wherein the initial state of the electrochromic component is a light-transmitting state, and the thin-film transistor component supplies electricity to the electrochromic component to control the light transmittance of the electrochromic component to decrease and gradually enter a light-shielding state; the microfluidic chip also includes a first contact layer and a second contact layer, the first contact layer covers the signal transmission layer, the photoresistor and the first driving electrode, the second contact layer and the first contact layer are arranged at intervals to form a receiving space, and the receiving space is used to receive micro-droplets; the microfluidic chip includes a first area and a second area, the first area and the second area both include the photoresistor, the first driving electrode, the electrochromic component and the thin-film transistor component, and the photoresistor, the first driving electrode, the electrochromic component and the thin-film transistor component in the first area and the photoresistor, the first driving electrode, the electrochromic component and the thin-film transistor component in the second area are relatively spaced and independently arranged; Providing a first light-emitting component, wherein the first light-emitting component is disposed on a side of the carrier substrate away from the photoresistor, and the first light-emitting component is used to emit an initial light; A second light-emitting component is provided, the second light-emitting component is arranged on a side of the carrier substrate facing the photoresistor, the second light-emitting component and the first light-emitting component are respectively arranged on two sides of the microfluidic chip, the second light-emitting component is used to emit a first light to the thin film transistor component, and control the light transmittance of the electrochromic component through the thin film transistor component; or a third light-emitting component is provided, the third light-emitting component is arranged corresponding to the receiving space, the third light-emitting component is used to emit a second light to the thin film transistor component, and control the light transmittance of the electrochromic component through the thin film transistor component; When the micro-droplets need to move from the first area to the second area of ​​the microfluidic chip, an initial light is irradiated on the side of the thin film transistor component away from the electrochromic component, and the initial light forms the preset light after passing through the electrochromic component; Controlling the thin film transistor component to be in a subthreshold state; The microfluidic chip is irradiated with a first light by the second light-emitting component. The micro-droplets in the first region are arranged between the thin-film transistor component and the second light-emitting component. When the first light passes through the micro-droplets, it will be affected by the micro-droplets, which will reduce the illumination intensity of the first light emitted to the channel layer of the thin-film transistor component in the first region, thereby reducing the degree of opening of the thin-film transistor component in the first region when it is in an open state. At this time, the transmittance of the electrochromic component is high, and the photoresistor in the first region receives the preset light with high light intensity and reduces its own resistance, thereby causing the voltage of the first driving electrode in the first region to be high. At the same time, the illumination intensity of the first light emitted to the channel layer of the thin-film transistor component in the second region is high, thereby causing the degree of opening of the thin-film transistor component in the second region to be high when it is in an open state. At this time, the transmittance of the electrochromic component is low, and the photoresistor in the second region receives the preset light with low light intensity and increases its own resistance, thereby causing the voltage of the first driving electrode in the second region to be low, so that the driving signal of the first driving electrode in the first region and the driving signal of the first driving electrode in the second region form a voltage difference, thereby forming a driving electric field. The micro-droplets are driven to move; or, the microfluidic chip is irradiated with a second light by the third light emitting component, and the micro-droplets are in the first area. When the second light passes through the micro-droplets, it will be affected by the micro-droplets, which will make the light intensity of the second light emitted to the channel layer of the thin film transistor component in the first area lower, so that the opening degree of the thin film transistor component in the first area is small when it is in the open state. At this time, the transmittance of the electrochromic component is high, and the photoresistor in the first area receives the preset light with high light intensity and reduces its own resistance, so that the voltage of the first driving electrode in the first area is high. At the same time, the light intensity of the second light emitted to the channel layer of the thin film transistor component in the second area is high, so that the opening degree of the thin film transistor component in the second area is large when it is in the open state. At this time, the transmittance of the electrochromic component is low, and the photoresistor in the second area receives the preset light with low light intensity and increases its own resistance, so that the voltage of the first driving electrode in the second area is low, so that the driving signal of the first driving electrode in the first area and the driving signal of the first driving electrode in the second area form a voltage difference, thereby forming a driving electric field to drive the micro-droplets to move.

2. A microfluidic chip, which controls the movement of microdroplets by the microdroplet control method according to claim 1, characterized in that: include: A carrier substrate; A signal transmission layer, disposed on the carrier substrate, and used for outputting an initial signal; A photoresistor connected to the signal transmission layer, the photoresistor is used to receive preset light, and the resistance value of the photoresistor changes according to the illumination intensity of the preset light; a first driving electrode connected to the photoresistor, the first driving electrode being used to form a driving signal according to the initial signal and the resistance value of the photoresistor, and the first driving electrode being used to drive the micro-droplet to move; An electrochromic component, arranged corresponding to the photoresistor and disposed between the photoresistor and the carrier substrate, the electrochromic component being used to transmit the initial light and form the preset light; A thin film transistor component is disposed on the carrier substrate and between the electrochromic component and the carrier substrate, the thin film transistor component is electrically connected to the electrochromic component, and the thin film transistor component is used to control the light transmittance of the electrochromic component to control the light intensity of the preset light; A light shielding member, the light shielding member is arranged on a side of the photoresistor away from the supporting substrate; A first contact layer and a second contact layer, the first contact layer covers the signal transmission layer, the photoresistor and the first driving electrode, the second contact layer and the first contact layer are spaced apart and form a receiving space, and the receiving space is used to receive micro-droplets; wherein the microfluidic chip includes a first area and a second area, the first area and the second area both include the photoresistor, the first driving electrode, the electrochromic component and the thin film transistor component, and the photoresistor, the first driving electrode, the electrochromic component and the thin film transistor component in the first area and the photoresistor, the first driving electrode, the electrochromic component and the thin film transistor component in the second area are relatively spaced apart and independently arranged.

3. The microfluidic chip according to claim 2, characterized in that: The thin film transistor assembly comprises a gate layer, a channel layer, a source layer, a drain layer and a second driving electrode, the gate layer and the channel layer are arranged correspondingly, the source layer and the drain layer are arranged at two ends of the channel layer respectively, and the second driving electrode is arranged on a side of the drain layer away from the carrier substrate; The electrochromic component comprises an electrochromic layer, which is arranged on a side of the second driving electrode away from the drain electrode layer, and the orthographic projection of the electrochromic layer on the carrier substrate covers the orthographic projection of the photoresistor on the carrier substrate.

4. A microfluidic device, characterized in that: The microfluidic device includes a first light-emitting component and the microfluidic chip described in any one of claims 2-3, the first light-emitting component is arranged on the side of the supporting substrate away from the photoresistor, and the first light-emitting component is used to emit initial light; the microfluidic device also includes a second light-emitting component, the second light-emitting component is arranged on the side of the supporting substrate facing the photoresistor, the second light-emitting component and the first light-emitting component are respectively arranged on both sides of the microfluidic chip, the second light-emitting component is used to emit a first light to a thin film transistor component, and control the light transmittance of the electrochromic component through the thin film transistor component.

5. A microfluidic device, characterized in that: The microfluidic device comprises a first light-emitting component and the microfluidic chip according to any one of claims 2 to 3, wherein the first light-emitting component is arranged on a side of the supporting substrate away from the photoresistor, and the first light-emitting component is used to emit initial light; The microfluidic chip comprises a first contact layer and a second contact layer, the first contact layer covers the first driving electrode, the first contact layer and the second contact layer are spaced apart to form a receiving space, and the receiving space is used to receive micro droplets; The microfluidic device includes a third light-emitting component, which is arranged corresponding to the receiving space and is used to emit a second light to the thin film transistor component and control the light transmittance of the electrochromic component through the thin film transistor component.

Citation Information

Patent Citations

  • P-n junction photoelectric effect-based device and p-n junction photoelectric effect-based method for optically controlling and driving liquid drops

    CN111167530A

  • Micro-fluidic chip and use method thereof

    CN111359688A