Preparation process of oral spray for inhibiting oral pathogens

Abstract

The present invention belongs to the technical field of traditional Chinese medicine preparations, and discloses a process for preparing an oral spray for inhibiting oral pathogens, comprising a tank body, a tank cover provided on the top of the tank body, a discharge pipe provided on the bottom of the tank cover, a control valve provided on the discharge pipe, a first motor fixedly mounted on the top of the tank cover, an output end of the first motor fixedly connected to a rotating shaft, one end of the rotating shaft extends through the tank cover to the interior of the tank body, and a first movable plate fixedly connected to the outer surface of the rotating shaft. Traditional Chinese medicine has a variety of active ingredients, such as flavonoids, volatile oils and polysaccharides, etc. These ingredients have broad-spectrum antibacterial, anti-inflammatory and therapeutic effects, providing a safer and more effective option for oral rehabilitation treatment. By comprehensively considering factors such as microbial composition, immune status and changes in oral mucosa, and by in-depth research on the regulatory effect of traditional Chinese medicine sprays on the oral microenvironment, a more comprehensive and accurate solution can be provided for post-implantation rehabilitation treatment, which is easy to use.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a preparation process of an oral spray for inhibiting oral pathogens. Background Art

[0002] After implant and tooth extraction surgery, there will be varying degrees and durations of wound pain, swelling, wound infection, wound dehiscence, bruising, and some patients may even develop peri-implantitis, leading to implant failure. To alleviate or prevent the occurrence of the above problems, dentists routinely use intravenous antibiotics + hormones or oral antibiotics, supplemented by gargles and other methods. Even so, the problem still exists. To address these problems, a pure Chinese medicine spray has been refined for use in rehabilitation treatment after implant and tooth extraction, effectively inhibiting the presence of pathogenic bacteria in the mouth and preventing oral diseases.

[0003] However, in the prior art, after the drug raw materials are soaked, they need to be squeezed and leaked to obtain a solution. The drug raw materials need to be squeezed multiple times to squeeze out all the solution in the raw materials, resulting in insufficient drug raw material leaching effect and low efficiency, which is not conducive to improving the production efficiency of oral sprays. Summary of the Invention

[0004] In view of the problems of the prior art, the present invention proposes the following technical solutions: a process for preparing an oral spray for inhibiting oral pathogens, comprising a tank body, a tank cover is provided on the top of the tank body, a discharge pipe is provided at the bottom of the tank cover, a control valve is provided on the discharge pipe, a first motor is fixedly installed on the top of the tank cover, an output end of the first motor is fixedly connected to a rotating shaft, one end of the rotating shaft passes through the tank cover and extends to the inside of the tank body, a first movable plate is fixedly connected to the outer surface of the rotating shaft, a second movable plate is provided inside the first movable plate, one end of the second movable plate is fixedly connected to a scraper, a filter plate is provided on the top of the scraper, a conveying port is provided on the filter plate, a partition plate is provided at the bottom of the scraper and the rotating shaft, the partition plate is fixedly installed to the inner wall of the tank, two movable ports are provided on the partition plate, two mounting grooves are provided inside the partition plate, the two mounting grooves are located on one side of the two movable ports, a first electric push rod is fixedly installed inside the mounting groove, and one end of the first electric push rod is fixedly connected to a sealing The sealing plate is located at the bottom of the two movable openings, and the second electric push rod is fixedly installed at the bottom of the second movable plate near the partition plate, and the extrusion plate is fixedly connected to the bottom of the second electric push rod. The delivery pipe is fixedly installed at both ends of the bottom of the partition plate, and the first filter screen is fixedly installed at the bottom end of the delivery pipe, and a second filter screen is arranged inside the delivery pipe. On one side of the second filter screen, an adjustment structure is arranged between the two delivery pipes, and a first magnetic block is arranged on the upper and lower sides of the adjustment structure. A movable opening is opened on one side of the delivery pipe, and a compression spring is fixedly connected to the inner wall of the bottom of the movable opening. A movable plate is provided on one side of the compression spring, and the movable plate is fixedly connected to the top of the connecting spring with the second magnetic block. The bottom of the first magnetic block is magnetically connected to the top of the second magnetic block. A strip opening is opened on the inner wall of the bottom of the movable opening, and the movable plate is movably connected to the inner wall of the strip opening. Slide blocks are fixedly connected on both sides of the top of the movable plate, and sliding grooves are opened on the inner walls on both sides of the movable opening, and the sliders are slidably connected to the sliding grooves;

[0005] The specific preparation process of the oral spray comprises the following steps:

[0006] Step 1: First, remove the lid of the tank, weigh the raw materials of Panax notoginseng, safflower, Corydalis yanhusuo, gallnut, clove, Bletilla striata, and mint in proportion to each other, grind them into coarse powder, filter the coarse powder through a filter plate for the first time, and then put the indigo bag into the tank through the delivery port;

[0007] Step 2: Pour 20,000 ml of 38-40% ethanol solution into the tank and reinstall the tank cover to the bottom of the tank;

[0008] Step 3: Then soak the raw materials, and drive the rotating shaft and the rotating plate to rotate by the first motor to fully stir the raw materials. Weigh the proportion of borneol and borax in the middle, pour them into the tank after dissolving, and add 0.3% mogroside to the solution in the late soaking period to mix the solution in the tank evenly. After mixing evenly, filter the solution;

[0009] Step 4: Finally, the moving port is exposed by moving the sealing plate, the raw material is transported to the inside of the delivery pipe, and filtered through the first filter screen and the second filter screen in the delivery pipe, and squeezed through the extrusion plate. The raw material is flipped over to the top of the first filter screen by adjusting the structure, and the flipped raw material is squeezed again. After all the solution in the raw material is squeezed out, it is discharged from the discharge pipe and packaged in spray bottles to obtain Chinese medicine spray.

[0010] As a preferred embodiment of the above technical solution, the ratio of the raw materials of Panax notoginseng, safflower, Corydalis yanhusuo, gallnut, clove, Bletilla striata, mint and Indigo naturalis is Panax notoginseng: 360 parts, safflower: 360 parts, Corydalis yanhusuo: 300 parts, gallnut: 360 parts, clove: 300 parts, Bletilla striata: 300 parts, mint: 300 parts, Indigo naturalis: 360 parts, borneol: 360 parts, borax: 280 parts, and mogroside 30 parts.

[0011] As a preferred embodiment of the above technical solution, the filter plate is located at the top of the inside of the tank body, the filter plate is fixedly connected to the inner wall of the tank body, the first movable plate is located on the outer surface of the rotating shaft and is distributed in a linear array, the second movable plate is movably connected to the inner wall of the first movable plate, and the second movable plate extends away from one end of the scraper to the inside of the fixed groove.

[0012] As a preferred embodiment of the above technical solution, a scraper block is provided at the bottom of the rotating shaft, the scraper block and the scraper are arranged in a cross shape, a fixed groove is opened inside the rotating shaft, a movable structure is provided inside the fixed groove, the second electric push rod and the extrusion plate are located on both sides of the rotating shaft, and they are symmetrically arranged with the center of the rotating shaft, the extrusion plate is located on the top of the partition plate, and the extrusion plate is arranged corresponding to the movable port and the sealing plate.

[0013] As a preferred embodiment of the above technical solution, the adjustment structure includes a dual-axis motor, the output ends on both sides of the dual-axis motor are fixedly connected to connecting rods, one end of the connecting rod passes through the movable port and is fixedly connected to the second filter screen, the top of the dual-axis motor is fixedly connected to a fixing frame, and telescopic columns are fixedly installed at both ends of the top of the fixing frame, and the top of the telescopic column is fixedly connected to the partition plate.

[0014] As a preferred embodiment of the above technical solution, the dual-axis motor, telescopic column and fixed frame are all located between the two conveying pipes, the second magnetic block is fixedly connected to the bottom of the connecting rod located inside the movable port, the strip port passes through the bottom end of the conveying pipe, and the movable plate is located inside the movable port close to the second filter screen.

[0015] As a preferred embodiment of the above technical solution, a movable groove is provided on the inner wall of the conveying pipe away from the movable port, an electric telescopic rod is fixedly installed inside the movable groove, a slot is provided on the side of the second filter screen close to the movable groove, one end of the electric telescopic rod passes through the inner wall of the conveying pipe and is plugged into the slot, a support plate is provided on one side of the movable groove, the top of the support plate is located at the bottom of the second filter screen, a connecting plate is fixedly connected to the top of the support plate, the connecting plate is located inside the movable groove, and the top of the connecting plate is fixedly connected to the electric telescopic rod.

[0016] As a preferred embodiment of the above technical solution, the moving structure includes a second motor, the conveying end of the second motor is fixedly connected to a threaded rod, the bottom of the threaded rod is rotatably connected to the inner wall of the bottom of the fixed groove, the outer surface of the threaded rod is threadedly connected to a moving block, both ends of the moving block are movably connected to a limiting rod, pushing plates are provided on both sides of the moving block, the threaded rod and the bottom end of the limiting rod are slidably connected to a sliding plate, the bottom of the sliding plate is fixedly connected to two fixed rods, one end of the two fixed rods passes through the bottom of the rotating shaft and is fixedly connected to the top of the scraping block.

[0017] As a preferred embodiment of the above technical solution, the second motor is fixedly installed on the top of the rotating shaft, the pushing plate is fixedly connected to the second movable plate on the side away from the limiting rod, the moving block is located between the two pushing plates and at the top of the pushing plate, the pushing plate and the moving block are both inclined surfaces on the opposite sides, the pushing plate is located on the top of the sliding plate, and the bottom of the sliding plate is fixedly connected to a connecting spring, the bottom of the connecting spring is fixedly installed on the inner wall of the bottom of the fixed groove, and the connecting spring is located between the fixed rod and the limiting rod.

[0018] The beneficial effects of the present invention are:

[0019] (1) The present invention uses traditional Chinese medicine to contain multiple active ingredients, such as flavonoids, volatile oils and polysaccharides, which have broad-spectrum antibacterial, anti-inflammatory and therapeutic effects, providing a safer and more effective option for oral rehabilitation treatment. By comprehensively considering factors such as microbial composition, immune status and changes in oral mucosa, and through in-depth research on the regulatory effect of traditional Chinese medicine sprays on the oral microenvironment, it can provide a more comprehensive and accurate solution for post-implantation rehabilitation treatment, which is easy to use;

[0020] (2) The present invention can turn over the extruded raw materials during the process of extruding the solution from the raw materials, so that the raw materials can be fully extruded, the force is evenly distributed, the number of extrusions is reduced, and the comprehensiveness of the raw material extrusion is improved, which is convenient for improving the low efficiency of drug raw material leaching and improving the production efficiency of oral sprays;

[0021] (3) The present invention can, when the raw materials are conveyed into the conveying pipe, drive the threaded rod to rotate by the second motor, so that the moving block pushes the pushing plate to drive the second movable plate to move the scraper, so that the scraper fits the inner wall of the tank, and at the same time drives the scraper block to move to the top of the partition plate through the sliding plate and the fixed rod. When the rotating shaft rotates, the scraper can scrape off the raw materials adhered to the inner wall of the tank. The rotation of the scraper block can push the raw materials into the conveying pipe from the moving port to leak, thereby improving the efficiency of raw material leakage and extrusion. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 What is shown is a schematic diagram of the overall structure of the embodiment;

[0023] Figure 2 What is shown is the internal structure diagram of the tank body of an embodiment;

[0024] Figure 3 Shown is a cross-sectional view of an embodiment tank body;

[0025] Figure 4 The structure diagram of the first movable plate, the partition plate and the scraper of the embodiment is shown;

[0026] Figure 5 Shown is a structural diagram of a mobile structure of an embodiment;

[0027] Figure 6 The embodiment shown is Figure 6 A magnified view of point A;

[0028] Figure 7 The embodiment shown is Figure 6 Enlarged view of point B;

[0029] Figure 8 Shown is a structural diagram of the internal structure and adjustment structure of the mounting slot of the embodiment;

[0030] Figure 9 Shown is a diagram of the internal structure of a delivery pipe according to an embodiment.

[0031] Figure 10 Shown is a diagram of the internal structure of the movable opening and the fixed groove of the embodiment.

[0032] In the figure: 1. Tank body; 2. Tank cover; 3. Discharge pipe; 4. Control valve; 5. First motor; 6. Delivery port; 7. Rotating shaft; 8. First movable plate; 9. Second movable plate; 10. Scraper; 11. Filter plate; 12. Separator plate; 13. First electric push rod; 14. Sealing plate; 15. Second electric push rod; 16. Extrusion plate; 17. Delivery pipe; 18. First filter screen; 19. Second filter screen; 20. Adjustment structure; 201. Dual-axis motor; 202 , connecting rod; 203, fixed frame; 204, telescopic column; 21, first magnetic block; 22, compression spring; 23, moving plate; 24, second magnetic block; 25, slider; 26, scraper block; 27, moving structure; 271, second motor; 272, threaded rod; 273, moving block; 274, limiting rod; 275, pushing plate; 276, sliding plate; 277, fixed rod; 28, electric telescopic rod; 29, support plate; 30, connecting plate; 31, connecting spring. DETAILED DESCRIPTION

[0033] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions of the present invention will be clearly and completely described below in conjunction with the embodiments.

[0034] Example 1:

[0035] The present invention provides a process for preparing an oral spray for inhibiting oral pathogens, such as Figure 1-10 As shown, it includes a tank body 1, a tank cover 2 is provided on the top of the tank body 1, a discharge pipe 3 is provided at the bottom of the tank cover 2, a control valve 4 is provided on the discharge pipe 3, a first motor 5 is fixedly installed on the top of the tank cover 2, the output end of the first motor 5 is fixedly connected to the rotating shaft 7, one end of the rotating shaft 7 passes through the tank cover 2 and extends to the inside of the tank body 1, a first movable plate 8 is fixedly connected to the outer surface of the rotating shaft 7, a second movable plate 9 is provided inside the first movable plate 8, a scraper 10 is fixedly connected to one end of the second movable plate 9, a filter plate 11 is provided on the top of the scraper 10, a conveying port 6 is provided on the filter plate 11, a partition plate 12 is provided at the bottom of the scraper 10 and the rotating shaft 7, the partition plate 12 is fixedly installed to the inner wall of the tank body 1, two moving ports are provided on the partition plate 12, two mounting grooves are provided inside the partition plate 12, the two mounting grooves are located on one side of the two moving ports, a first electric push rod 13 is fixedly installed inside the mounting groove, one end of the first electric push rod 13 is fixedly connected to a sealing plate 14, the sealing plate 14 is located at the bottom of the two moving ports, close to the partition plate 12 A second electric push rod 15 is fixedly installed at the bottom of the second movable plate 9, and an extrusion plate 16 is fixedly connected to the bottom of the second electric push rod 15. A delivery pipe 17 is fixedly installed at both ends of the bottom of the partition plate 12, and a first filter screen 18 is fixedly installed at the bottom end of the delivery pipe 17. A second filter screen 19 is provided inside the delivery pipe 17. An adjustment structure 20 is provided on one side of the second filter screen 19 and between the two delivery pipes 17. A first magnetic block 21 is provided on the upper and lower sides of the adjustment structure 20. A movable opening is provided on one side of the delivery pipe 17, and a compression spring 22 is fixedly connected to the inner wall of the bottom of the movable opening. A movable plate 23 is provided on one side of the compression spring 22. A second magnetic block 24 is fixedly connected to the top of the movable plate 23 and the connecting spring 31. The bottom of the first magnetic block 21 is magnetically connected to the top of the second magnetic block 24. A strip opening is provided on the inner wall of the bottom of the movable opening, and the movable plate 23 is movably connected to the inner wall of the strip opening. Slide blocks 25 are fixedly connected on both sides of the top of the movable plate 23, and sliding grooves are provided on the inner walls on both sides of the movable opening. The slide blocks 25 are slidably connected to the sliding grooves;

[0036] The specific preparation process of the oral spray comprises the following steps:

[0037] Step 1: First, remove the tank lid 2, weigh the raw materials of Panax notoginseng, safflower, Corydalis yanhusuo, gallnut, clove, Bletilla striata, and mint in proportion to each other, and grind them into coarse powder. After the coarse powder is initially filtered through the filter plate 11, it is placed inside the tank body 1, and the Indigo Naturalis bag is placed into the tank body 1 through the delivery port 6;

[0038] Step 2: Then pour 20,000 ml of 38-40% mass concentration ethanol solution into the tank body 1 and reinstall the tank cover 2 to the bottom of the tank body 1;

[0039] Step 3: Then soak the raw materials, and drive the rotating shaft 7 and the rotating plate to rotate by the first motor 5, and fully stir the raw materials. Weigh the proportion of borneol and borax in the middle, pour them into the tank body 1 after dissolving, and add 0.3% mogroside to the solution in the late soaking period to make the solution inside the tank body 1 evenly mixed. After mixing evenly, filter the solution;

[0040] Step 4: Finally, the moving port is exposed by moving the sealing plate 14, and the raw material is transported to the inside of the delivery pipe 17, and filtered through the first filter screen 18 and the second filter screen 19 in the delivery pipe 17, and squeezed through the squeezing plate 16. The raw material is flipped over to the top of the first filter screen 18 through the adjusting structure 20, and the flipped raw material is squeezed again. After all the solution in the raw material is squeezed out, it is discharged from the discharge pipe 3 and packaged in spray bottles to obtain a Chinese medicine spray.

[0041] The ratio of Panax notoginseng, safflower, Corydalis yanhusuo, gallnut, clove, Bletilla striata, mint and Indigo naturalis is as follows: Panax notoginseng: 360 parts, safflower: 360 parts, Corydalis yanhusuo: 300 parts, gallnut: 360 parts, clove: 300 parts, Bletilla striata: 300 parts, mint: 300 parts, Indigo naturalis: 360 parts, borneol: 360 parts, borax: 280 parts and mogroside 30 parts.

[0042] When preparing the traditional Chinese medicine spray, first weigh the raw materials of Panax notoginseng, safflower, Corydalis yanhusuo, gallnut, clove, Bletilla striata and mint in proportion, then coarsely grind the raw materials, and when the raw materials are ground into coarse powder, open the tank cover 2, pour the ground raw materials into the interior of the tank body 1, filter through the filter plate 11 to filter out impurities inside the raw materials, then put the indigo bag into the interior of the tank body 1 through the conveying port 6, install the tank cover 2 on the top of the tank body 1, soak the raw materials, and start the first motor 5 to drive the rotating shaft 7 and the first movable plate 8, the second movable plate 9 and the scraper 10 to rotate during the soaking process to stir the soaked raw materials. When the movable plate 9 rotates, it drives the second electric push rod 15 and the squeezing plate 16 to rotate on the top of the partition plate 12 to fully stir the soaked raw materials. When the soaking is completed, the squeezing plate 16 rotates to separate from the moving port, and the first electric push rod 13 is started to drive the sealing plate 14 to move, exposing the moving port, so that the solution and raw materials inside the tank body 1 enter the inside of the conveying pipe 17, and are filtered through the first filter 18 and the second filter 19. The control valve 4 is controlled to discharge the solution from the discharge pipe 3 for collection. When the raw materials fall on the first filter 18 in the conveying pipe 17, the first motor 5 and the rotating shaft 7 are rotated to make the first filter 18 and the second filter 19 be filtered. The movable plate 8 and the second movable plate 9 drive the second electric push rod 15 to rotate, so that the extrusion plate 16 moves to the top of the movable port, and then the first electric push rod 13 is started to make the extrusion plate 16 move to the inside of the conveying pipe 17 through the movable port, so that the extrusion plate 16 moves to the top of the second filter plate 11, and squeezes the raw materials remaining on the second filter plate 11. After the solution is squeezed out, the second filter screen 19 is rotated by the adjustment structure 20 to separate the first magnetic block 21 from the second magnetic block 24. After the second filter screen 19 is turned over, the first magnetic block 21 connected to the adjustment structure 20 on one side is attracted to the second magnetic block 24, so that the residual The raw material falls onto the first filter screen 18, and then the second filter screen 19 is squeezed by the squeezing plate 16. The second filter screen 19 squeezes the first filter screen 18 downward, so that the telescopic rod extends, and the fixing frame 203 drives the dual-axis motor 201 and the connecting rod 202 to move downward, so that the connecting spring 31 at the bottom of the first magnetic block 21 is compressed, and the sliders 25 on both sides of the movable plate 23 move along the slide groove. When the movable plate 23 moves to the bottom of the movable opening, the second filter screen 19 can squeeze the raw material on the first filter screen 18, so that the raw material can be fully squeezed, so that the solution can be fully squeezed out, thereby improving the solution leaching effect and facilitating use.

[0043] like Figure 1-4As shown, the filter plate 11 is located at the top of the tank body 1, the filter plate 11 is fixedly connected to the inner wall of the tank body 1, the first movable plate 8 is located on the outer surface of the rotating shaft 7 and is distributed in a linear array, the second movable plate 9 is movably connected to the inner wall of the first movable plate 8, the second movable plate 9 extends to the inside of the fixed groove away from one end of the scraper 10, a scraper block 26 is provided at the bottom of the rotating shaft 7, the scraper block 26 and the scraper 10 are arranged in a cross shape, a fixed groove is opened inside the rotating shaft 7, and a movable structure 27 is provided inside the fixed groove, the second electric push rod 15 and the extrusion plate 16 are located on both sides of the rotating shaft 7, and are symmetrically arranged with the center of the rotating shaft 7, the extrusion plate 16 is located at the top of the partition plate 12, and the extrusion plate 16 is arranged corresponding to the moving port and the sealing plate 14.

[0044] The holes on the filter plate 11 are small and can filter the coarse powder raw materials, thereby facilitating the filtering of the coarse powder raw materials and filtering out impurities inside the coarse powder raw materials to prevent the impurities from affecting the soaking effect. The first movable plate 8 and the second movable plate 9 are distributed in a linear array. When the rotating shaft 7 rotates, the first movable plate 8 and the second movable plate 9 are driven to rotate, so as to stir the soaked raw materials for thorough mixing. The movable structure 27 is installed through the fixed groove. When the movable structure 27 is started to move the second movable plate 9 on the inner wall of the first movable plate 8, the second movable plate 9 pushes the scraper 10 to move toward the inner wall of the tank body 1, so that one side of the scraper 10 is in contact with the inner wall of the tank body 1, so that the scraper 10 can scrape off the raw materials adhering to the inner wall of the tank body 1 when the scraper 10 rotates. At the same time, the movable structure 27 moves and pushes the scraper block 26 to the top of the partition plate 12, so as to push the raw materials to the moving port, and then move from the moving port to the inside of the conveying pipe 17 for filtration and leakage, so as to improve the efficiency of raw material leakage and leaching.

[0045] like Figure 8-9 As shown, the adjustment structure 20 includes a dual-axis motor 201, and the output ends on both sides of the dual-axis motor 201 are fixedly connected to a connecting rod 202, one end of the connecting rod 202 passes through the movable port and is fixedly connected to the second filter 19, and the top of the dual-axis motor 201 is fixedly connected to a fixing frame 203, and telescopic columns 204 are fixedly installed at both ends of the top of the fixing frame 203, and the top of the telescopic column 204 is fixedly connected to the partition plate 12.

[0046] By starting the dual-axis motor 201 to drive the connecting rod 202 to rotate, the connecting rod 202 drives the second filter screen 19 to rotate, so that the raw material on the second filter screen 19 is flipped to the top of the first filter screen 18. When the extrusion plate 16 moves downward to squeeze the second filter screen 19, the telescopic column 204 is extended to push the fixing frame 203 to drive the second filter plate 11 to move downward. The moving extrusion of the second filter screen 19 facilitates the full and comprehensive extrusion of the raw material. Since the holes on the first filter screen 18 and the second filter screen 19 are smaller than the radius of the raw material, it is convenient to perform re-filtration, thereby improving the solution leaching effect.

[0047] like Figure 8-10 As shown, the dual-axis motor 201, the telescopic column 204 and the fixed frame 203 are all located between the two conveying pipes 17, the second magnetic block 24 is fixedly connected to the bottom of the connecting rod 202 located inside the movable port, the strip port passes through the bottom end of the conveying pipe 17, and the movable plate 23 is located inside the movable port near the side of the second filter 19.

[0048] Since the dual-axis motor 201, the telescopic column 204 and the fixed frame 203 are all located between the two conveying pipes 17, the telescopic column 204 and the fixed frame 203 facilitate the fixation of the dual-axis motor 201. When the dual-axis motor 201 drives the connecting rod 202 to rotate, it is convenient to turn over the second filter screens 19 inside the two conveying pipes 17 at the same time, thereby improving efficiency. When the first magnetic block 21 and the second magnetic block 24 facilitate the up and down movement of the first filter screen 18 in the conveying pipe 17, the movable plate 23 can be driven to move in the strip-shaped opening. When the second filter screen 19 moves to the first filter screen 18 and penetrates the bottom end of the conveying pipe 17, the movable plate 23 is located inside the movable opening near the side of the second filter screen 19. When the raw materials at the bottom are squeezed, the movable plate 23 moves to the bottom of the delivery pipe 17 through the strip mouth. When the second filter screen 19 moves to its original position, the movable plate 23 moves to the inside of the movable mouth through the strip mouth, thereby blocking the movable mouth to prevent the raw materials from falling from the movable mouth into the solution at the bottom of the tank body 1 after being turned over, so that when the raw materials are discharged with the solution, the discharge pipe 3 is blocked.

[0049] like Figure 9-10 As shown, a movable groove is provided on the inner wall of the conveying pipe 17 away from the movable port, and an electric telescopic rod 28 is fixedly installed inside the movable groove. A slot is provided on the side of the second filter screen 19 close to the movable groove. One end of the electric telescopic rod 28 passes through the inner wall of the conveying pipe 17 and is plugged into the slot. A support plate 29 is provided on one side of the movable groove. The top of the support plate 29 is located at the bottom of the second filter screen 19. A connecting plate 30 is fixedly connected to the top of the support plate 29. The connecting plate 30 is located inside the movable groove, and the top of the connecting plate 30 is fixedly connected to the electric telescopic rod 28.

[0050] The electric telescopic rod 28 is installed through the movable groove, and the electric telescopic rod 28 is plugged into the slot on one side of the second filter screen 19, which is convenient for fixing the second filter screen 19 on the top of the conveying pipe 17. At the same time, the bottom of the filter screen is supported by the support plate 29, so that when the extrusion plate 16 squeezes the raw material on the top of the second filter screen 19, the second filter screen 19 remains stable. When the second filter screen 19 needs to be flipped, the connecting plate 30 is driven to move by the electric telescopic rod 28. When one end of the electric telescopic rod 28 moves to the inside of the movable groove, it is no longer plugged into the slot. The connecting plate 30 drives the support plate 29 to move into the inside of the movable groove and no longer supports the bottom of the second filter screen 19, so that the second filter screen 19 is no longer restricted. The second filter screen 19 is driven to flip through the action of the dual-axis motor 201 and the connecting rod 202, which is beneficial to improving the proximity effect of the raw materials.

[0051] like Figure 3-7 As shown, the moving structure 27 includes a second motor 271, and the conveying end of the second motor 271 is fixedly connected to a threaded rod 272, the bottom of the threaded rod 272 is rotatably connected to the inner wall of the bottom of the fixed groove, the outer surface of the threaded rod 272 is threadedly connected to a moving block 273, and both ends of the moving block 273 are movably connected to a limiting rod 274. Push plates 275 are provided on both sides of the moving block 273, and the bottom ends of the threaded rod 272 and the limiting rod 274 are slidably connected to a sliding plate 276. The bottom of the sliding plate 276 is fixedly connected to two fixed rods 277, and one end of the two fixed rods 277 passes through the bottom of the rotating shaft 7 and connects to the scraper block. 26 is fixedly connected to the top, the second motor 271 is fixedly installed on the top of the rotating shaft 7, the pushing plate 275 is fixedly connected to the second movable plate 9 on the side away from the limiting rod 274, the moving block 273 is located between the two pushing plates 275, and is located at the top of the pushing plate 275, and the opposite sides of the pushing plate 275 and the moving block 273 are both inclined surfaces, the pushing plate 275 is located at the top of the sliding plate 276, and the bottom of the sliding plate 276 is fixedly connected to the connecting spring 31, the bottom of the connecting spring 31 is fixedly installed with the inner wall of the bottom of the fixing groove, and the connecting spring 31 is located between the fixing rod 277 and the limiting rod 274.

[0052] The threaded rod 272 is driven to rotate by the second motor 271, so that the moving block 273 moves downward under the action of the limiting rod 274. Since the opposite sides of the pushing plate 275 and the moving block 273 are both inclined surfaces, when the moving block 273 moves downward along the threaded rod 272 between the pushing plates 275, the moving block 273 squeezes the pushing plate 275, so that the pushing plate 275 pushes the second movable plate 9 to drive the scraper 10 to move and fit the inner wall of the tank body 1. At the same time, when the moving block 273 moves to the bottom of the threaded rod 272, the moving block 273 pushes the sliding plate 276 and the fixed rod 277 to move downward, and the connecting spring 31 is compressed, so that the bottom of the scraper block 26 fits the top of the partition plate 12. After the soaking is completed and the soaked raw materials are discharged, the rotating shaft 7 is rotated, so that the second movable plate 9 drives the scraper 10 to rotate, so that the raw materials adhered to the inner wall of the tank body 1 are scraped off, and the raw materials are pushed into the moving port through the rotation of the scraper block 26 and transported to the inside of the conveying pipe 17 for extrusion and leakage, thereby improving the effect of raw material transportation.

[0053] Example 2:

[0054] The main benefits of this formula are:

[0055] Panax notoginseng can dissolve blood stasis and stop bleeding, promote blood circulation and relieve pain, detoxify and reduce swelling, and is used for various types of bleeding caused by injuries;

[0056] Safflower has the functions of promoting blood circulation, dredge menstruation, remove blood stasis and relieve pain, and is effective in treating various injuries caused by falls;

[0057] Yuanhusuo has the functions of promoting blood circulation, relieving pain, and promoting qi circulation, and can be used for a variety of diseases;

[0058] Gallnut has the function of astringency and tissue regeneration. Its main component is tannin, which can combine with protein to form a water-insoluble macromolecular precipitate, thereby forming a pseudomembrane on oral mucosal wounds to protect them. The coagulation of bacterial protein will affect bacterial nutritional metabolism and have a bactericidal effect.

[0059] Borneol has the effects of clearing heat and detoxifying, invigorating the mind, promoting tissue regeneration and promoting wound healing; Indigo has the effects of clearing heat and detoxifying, cooling blood, and is mainly used to treat mouth and tongue sores; the main effect of clove is analgesia and anti-inflammation; Bletilla striata also has the effect of astringency and hemostasis; the main effect of borax is clearing heat and detoxifying, antibacterial and antiseptic, and has varying degrees of inhibitory effects on both S. grosvenori-positive and S. grosvenori-negative bacteria, skin fungi and Streptococcus albus; Peppermint and Momordica glycosides are cooling and refreshing, and their main function is to serve as seasoning in the prescription.

[0060] The above 10 Chinese medicines are rationally formulated and combined. The prescription contains both trauma medicines for bruises, hemostasis, swelling reduction, blood stasis removal, qi circulation and pain relief, as well as medicines for astringency, tissue regeneration, antiseptic, sterilization, and promoting the healing of wounds and ulcers. The efficacy of each medicine is fully exerted and complements each other. At the same time, the prescription is easy to carry and very convenient to use, and it is a pure Chinese medicine preparation without any toxic side effects.

[0061] Example 3:

[0062] Clinical treatment effect observation method of the present invention

[0063] General information: 80 patients underwent tooth extraction, aged between 17 and 42 years, including 45 males and 35 females, 80% of whom underwent flap surgery to extract impacted teeth; 72 patients underwent implant surgery, aged between 35 and 80 years, including 43 males and 29 females. The 152 patients were randomly divided into treatment group, mixed group, and control group.

[0064] The treatment group consisted of 52 people. They used Beijingsha oral rehabilitation spray after surgery. The spray was applied to the wound once every 1-2 hours, held in the mouth for 1-3 minutes, then spitted out or swallowed. The spray was used for 3-5 consecutive days.

[0065] The control group of 47 patients received intravenous antibiotics or oral antibiotics for 3-5 days after surgery.

[0066] The mixed group of 53 people received intravenous or oral antibiotics after surgery, and also used Beijingsha oral rehabilitation spray at the same time, with the same usage as before.

[0067] The duration of postoperative pain (hours) in each group of patients was observed, as were swelling, bruising, wound infection (redness, swelling, exudate), and wound dehiscence. The observation period was within 15 days.

[0068] Efficacy judgment criteria (self-made)

[0069] Significantly effective: no pain (short-term slight pain), no swelling, no bruising, no infection, no wound dehiscence.

[0070] Effective: pain duration < 24 hours, swelling duration < 72 hours, bruising duration < 1 week, mild wound infection or no wound dehiscence.

[0071] Ineffective: pain duration > 48 hours, swelling duration > 5 days, bruising duration > 12 days, obvious wound infection, and some wounds dehiscence.

[0072] The efficacy results of the three groups are:

[0073] The total effective rate of the treatment group was 82%

[0074] The total effective rate of the mixed group was 91%

[0075] The total effective rate of the control group was 76%

[0076] The treatment results show that the Chinese medicine spray of the present invention is indeed a natural antibiotic, which not only has a very satisfactory bactericidal effect, but is also an ideal rehabilitation treatment drug after oral implant and tooth extraction surgery.

[0077] Beneficial effects of the technical solution of this application

[0078] (1) Innovation of academic viewpoints:

[0079] Traditional Chinese Medicine-Based Oral Antibacterial Therapy: Traditional oral antibacterial treatments often rely on chemically synthesized drugs. The traditional Chinese medicine spray described in this invention represents a treatment approach based on traditional Chinese medicine ingredients. Traditional Chinese medicine contains a variety of active ingredients, such as flavonoids, volatile oils, and polysaccharides. These ingredients possess broad-spectrum antibacterial, anti-inflammatory, and therapeutic properties, providing a safer and more effective option for oral rehabilitation.

[0080] Comprehensively consider the impact of the oral microenvironment: The success of post-implant rehabilitation is closely related to the oral microenvironment. The Chinese herbal spray described in this invention focuses on its impact on the oral microenvironment, taking into account factors such as microbial composition, immune status, and changes in the oral mucosa. By further studying the regulatory effects of the Chinese herbal spray described in this invention on the oral microenvironment, a more comprehensive and precise solution for post-implant rehabilitation can be provided.

[0081] (2) Innovation in research methods:

[0082] Combination therapy with antibiotics and antibacterial solutions: While previous studies may have focused primarily on single treatments, this study introduces a combination of antibiotics and the traditional Chinese medicine spray described in this invention. This combination therapy may have a synergistic effect, potentially improving microcirculatory and periodontal markers, and healing outcomes. This allows for comparison of the efficacy of different treatments compared to previous studies.

[0083] Expected social benefits:

[0084] (1) Improve the effect of post-implant rehabilitation treatment: The Chinese medicine spray of the present invention is a new oral antibacterial treatment method. Its application can effectively prevent post-implant infection and promote wound healing and rehabilitation. When patients receive post-implant rehabilitation treatment, they can obtain better treatment effects, reduce the occurrence of infection and complications, and improve their quality of life;

[0085] (2) Reduce the abuse of antibiotics: Traditional oral antibacterial treatment often relies on the use of antibiotics, while the Chinese medicine spray in the present invention is a natural antibacterial treatment method that avoids the abuse of antibiotics. This has positive significance for reducing the formation of antibiotic resistance. By promoting the use of the Chinese medicine spray in the present invention, the dependence of patients on antibiotics after oral implant surgery can be reduced, reducing the potential risks brought about by the abuse of antibiotics;

[0086] (3) Promoting the development of oral Chinese medicine treatment: This project promotes the application and development of Chinese medicine treatment in the field of oral medicine by introducing the Chinese medicine spray of the present invention. Oral Chinese medicine treatment has a long history and rich experience. Scientific research to verify the efficacy of oral Chinese medicine can provide new treatment ideas and methods for oral medicine and broaden the scope of oral medicine treatment.

[0087] Working principle: When in use, first weigh the proportion of Panax notoginseng, safflower, Corydalis yanhusuo, gallnut, clove, Bletilla striata and mint raw materials, then coarsely grind the above raw materials, and when the raw materials are ground into coarse powder, open the tank cover 2, pour the ground raw materials into the tank body 1, filter through the filter plate 11 to filter out the impurities inside the raw materials, and then put the indigo bag into the tank body 1 through the conveying port 6. After installing the tank cover 2 on the top of the tank body 1, soak the raw materials. During the soaking process, start the first motor 5 to drive the rotating shaft 7 and the first movable plate 8, the second movable plate 9 and the scraper 10 to rotate, and stir the soaked raw materials. When the second movable plate 9 rotates, it drives the second electric push rod 15 and the squeezing plate 16 to rotate on the top of the partition plate 12 to fully stir the soaked raw materials. When the soaking is completed, the squeezing plate 16 rotates to separate from the moving port, and the first electric push rod 13 is started to drive the sealing plate 14 to move, and the moving port is exposed, so that the solution and raw materials inside the tank body 1 enter the inside of the conveying pipe 17, and are filtered through the first filter screen 18 and the second filter screen 19. The control valve 4 is controlled to discharge the solution from the discharge pipe 3 for collection. When the raw materials fall on the first filter screen 18 in the conveying pipe 17, the first motor 5 and the rotation of the rotating shaft 7 make The first movable plate 8 and the second movable plate 9 drive the second electric push rod 15 to rotate, so that the extrusion plate 16 moves to the top of the movable port, and then the first electric push rod 13 is started to make the extrusion plate 16 move to the inside of the conveying pipe 17 through the movable port, so that the extrusion plate 16 moves to the top of the second filter plate 11, and squeezes the raw materials remaining on the second filter plate 11. After the solution is squeezed out, the connecting rod 202 is driven to rotate by the dual-axis motor 201, and the connecting rod 202 rotates the second filter screen 19, so that the first magnetic block 21 is separated from the second magnetic block 24. After the second filter screen 19 is turned over, the first magnetic block 21 connected to the other side of the connecting rod 202 is rotated. The magnetic block 21 and the second magnetic block 24 attract each other. When the residual raw material falls onto the first filter screen 18, the second filter screen 19 is squeezed by the squeezing plate 16. The second filter screen 19 squeezes the first filter screen 18 downward, so that the telescopic rod extends, and the fixed frame 203 drives the dual-axis motor 201 and the connecting rod 202 to move downward, so that the connecting spring 31 at the bottom of the first magnetic block 21 is compressed, and the sliders 25 on both sides of the movable plate 23 move along the slide groove. When the movable plate 23 moves to the bottom of the movable opening, the second filter screen 19 can squeeze the raw material on the first filter screen 18, so that the raw material can be fully squeezed and easily squeezed out.

[0088] When the raw material leaches and leaks, the second motor 271 drives the threaded rod 272 to rotate, so that the moving block 273 moves downward under the action of the limiting rod 274. Since the pushing plate 275 and the moving block 273 on the opposite side are both inclined, when the moving block 273 moves downward along the threaded rod 272 between the pushing plates 275, the moving block 273 squeezes the pushing plate 275, so that the pushing plate 275 pushes the second movable plate 9 to drive the scraper 10 to move and fit the inner wall of the tank body 1. At the same time, when the moving block 273 moves to the threaded rod 274, the second movable plate 9 drives the scraper 10 to move and fit the inner wall of the tank body 1. When the rod 272 reaches the bottom, the moving block 273 pushes the sliding plate 276 and the fixed rod 277 to move downward, and the connecting spring 31 is compressed, so that the bottom of the scraper block 26 fits into the top of the partition plate 12. When the soaking is completed and the soaked raw materials are discharged, the rotating shaft 7 is rotated to rotate the second movable plate 9 to drive the scraper 10 to rotate, so that the raw materials adhered to the inner wall of the tank body 1 are scraped off, and the raw materials are pushed into the moving port through the rotation of the scraper block 26 and transported to the inside of the conveying pipe 17 for extrusion and leakage, so as to improve the effect of raw material transportation.

[0089] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit the same.

Claims

1. A process for preparing an oral spray for inhibiting oral pathogens, comprising a tank (1), characterized in that: The tank body (1) is provided with a tank cover (2) on the top, a discharge pipe (3) is provided at the bottom of the tank cover (2), a control valve (4) is provided on the discharge pipe (3), a first motor (5) is fixedly installed on the top of the tank cover (2), an output end of the first motor (5) is fixedly connected to a rotating shaft (7), one end of the rotating shaft (7) passes through the tank cover (2) and extends to the inside of the tank body (1), a first movable plate (8) is fixedly connected to the outer surface of the rotating shaft (7), a second movable plate (9) is provided inside the first movable plate (8), one end of the second movable plate (9) is fixedly connected to a scraper (10), and the top of the scraper (10) is provided with a A filter plate (11) is provided, a conveying port (6) is provided on the filter plate (11), a partition plate (12) is provided at the bottom of the scraper (10) and the rotating shaft (7), the partition plate (12) is fixedly installed on the inner wall of the tank body (1), two movable ports are provided on the partition plate (12), two mounting grooves are provided inside the partition plate (12), the two mounting grooves are located on one side of the two movable ports, a first electric push rod (13) is fixedly installed inside the mounting groove, one end of the first electric push rod (13) is fixedly connected to a sealing plate (14), the sealing plate (14) is located at the bottom of the two movable ports, close to the A second electric push rod (15) is fixedly installed at the bottom of the second movable plate (9) of the partition plate (12), and an extrusion plate (16) is fixedly connected to the bottom of the second electric push rod (15). A delivery pipe (17) is fixedly installed at both ends of the bottom of the partition plate (12), and a first filter (18) is fixedly installed at the bottom end of the delivery pipe (17). A second filter (19) is provided inside the delivery pipe (17). An adjustment structure (20) is provided on one side of the second filter (19) and between the two delivery pipes (17). A first magnetic block (21) is provided on both the upper and lower sides of the adjustment structure (20). The delivery pipe ( 17) A movable opening is provided on one side, a compression spring (22) is fixedly connected to the inner wall of the bottom of the movable opening, a movable plate (23) is provided on one side of the compression spring (22), a second magnetic block (24) is fixedly connected to the top of the movable plate (23) and the connecting spring (31), the bottom of the first magnetic block (21) is magnetically connected to the top of the second magnetic block (24), a strip opening is provided on the inner wall of the bottom of the movable opening, the movable plate (23) is movably connected to the inner wall of the strip opening, sliders (25) are fixedly connected to both sides of the top of the movable plate (23), sliding grooves are provided on the inner walls on both sides of the movable opening, and the sliders (25) are slidably connected to the sliding grooves; A movable groove is provided on the inner wall of the conveying pipe (17) away from the movable opening, an electric telescopic rod (28) is fixedly installed inside the movable groove, a slot is provided on the side of the second filter (19) close to the movable groove, one end of the electric telescopic rod (28) passes through the inner wall of the conveying pipe (17) and is plugged into the slot, a support plate (29) is provided on one side of the movable groove, the top of the support plate (29) is located at the bottom of the second filter (19), a connecting plate (30) is fixedly connected to the top of the support plate (29), the connecting plate (30) is located inside the movable groove, and the top of the connecting plate (30) is fixedly connected to the electric telescopic rod (28); The specific preparation process of the oral spray comprises the following steps: Step 1: First, remove the can lid (2), weigh the raw materials of Panax notoginseng, safflower, Corydalis yanhusuo, gallnut, clove, white schizonepeta, and mint in proportion to each other, and grind them into coarse powder. The coarse powder is filtered through the filter plate (11) and then placed into the can body (1). The indigo bag is placed into the can body (1) through the delivery port (6); Step 2: Then pour 20,000 ml of ethanol solution with a mass concentration of 38-40% into the tank body (1) and reinstall the tank cover (2) to the bottom of the tank body (1); Step 3: Then, the raw materials are soaked, and the rotating shaft (7) and the rotating plate are driven to rotate by the first motor (5), and the raw materials are fully stirred. During the process, borneol and borax are weighed and poured into the tank body (1) after dissolving. At the end of the soaking, 0.3% mogroside is added to the solution so that the solution inside the tank body (1) is evenly mixed. After the solution is evenly mixed, the solution is filtered; Step 4: Finally, the sealing plate (14) is moved to expose the movable port, and the raw material is transported to the inside of the delivery pipe (17), and filtered through the first filter screen (18) and the second filter screen (19) in the delivery pipe (17), and squeezed through the squeezing plate (16). The raw material is flipped over to the top of the first filter screen (18) by the adjusting structure (20), and the flipped raw material is squeezed again. After all the solution in the raw material is squeezed out, it is discharged from the discharge pipe (3) and packaged in spray bottles to obtain a Chinese medicine spray.

2. The process for preparing an oral spray for inhibiting oral pathogens according to claim 1, characterized in that: The ratio of the raw materials of Panax notoginseng, safflower, Corydalis yanhusuo, gallnut, clove, Bletilla striata, mint and Indigo naturalis is as follows: Panax notoginseng: 360 parts, safflower: 360 parts, Corydalis yanhusuo: 300 parts, gallnut: 360 parts, clove: 300 parts, Bletilla striata: 300 parts, mint: 300 parts, Indigo naturalis: 360 parts, borneol: 360 parts, borax: 280 parts and mogroside: 30 parts.

3. The process for preparing an oral spray for inhibiting oral pathogens according to claim 1, characterized in that: The filter plate (11) is located at the top end of the tank body (1), and the filter plate (11) is fixedly connected to the inner wall of the tank body (1). The first movable plate (8) is located on the outer surface of the rotating shaft (7) and is distributed in a linear array. The second movable plate (9) is movably connected to the inner wall of the first movable plate (8), and the second movable plate (9) extends away from one end of the scraper (10) to the inside of the fixed groove.

4. The process for preparing an oral spray for inhibiting oral pathogens according to claim 1, characterized in that: A scraper (26) is provided at the bottom of the rotating shaft (7), and the scraper (26) and the scraper (10) are arranged in a cross shape. A fixed groove is provided inside the rotating shaft (7), and a movable structure (27) is provided inside the fixed groove. The second electric push rod (15) and the extrusion plate (16) are located on both sides of the rotating shaft (7) and are symmetrically arranged with respect to the center of the rotating shaft (7). The extrusion plate (16) is located on the top of the partition plate (12), and the extrusion plate (16) is arranged corresponding to the movable port and the sealing plate (14).

5. The process for preparing an oral spray for inhibiting oral pathogens according to claim 1, characterized in that: The regulating structure (20) comprises a dual-axis motor (201), both output ends of the dual-axis motor (201) are fixedly connected to connecting rods (202), one end of the connecting rod (202) passes through the movable opening and is fixedly connected to the second filter (19), the top of the dual-axis motor (201) is fixedly connected to a fixing frame (203), the top ends of the fixing frame (203) are fixedly mounted with telescopic columns (204), and the top of the telescopic columns (204) is fixedly connected to the partition plate (12).

6. The process for preparing an oral spray for inhibiting oral pathogens according to claim 5, characterized in that: The dual-axis motor (201), telescopic column (204) and fixed frame (203) are all located between the two conveying pipes (17); the second magnetic block (24) is fixedly connected to the bottom of the connecting rod (202) located inside the movable opening; the strip opening passes through the bottom end of the conveying pipe (17); and the movable plate (23) is located inside the movable opening on a side close to the second filter (19).

7. The process for preparing an oral spray for inhibiting oral pathogens according to claim 4, characterized in that: The movable structure (27) comprises a second motor (271), the conveying end of the second motor (271) is fixedly connected to a threaded rod (272), the bottom of the threaded rod (272) is rotatably connected to the inner wall of the bottom of the fixed groove, the outer surface of the threaded rod (272) is threadedly connected to a movable block (273), both ends of the movable block (273) are movably connected to a limiting rod (274), and pushing plates (275) are provided on both sides of the movable block (273). The threaded rod (272) and the bottom end of the limiting rod (274) are slidably connected to a sliding plate (276), and the bottom of the sliding plate (276) is fixedly connected to two fixed rods (277), and one end of the two fixed rods (277) passes through the bottom of the rotating shaft (7) and is fixedly connected to the top of the scraping block (26).

8. The process for preparing an oral spray for inhibiting oral pathogens according to claim 7, characterized in that: The second motor (271) is fixedly mounted on the top of the rotating shaft (7), the pushing plate (275) is fixedly connected to the second movable plate (9) on the side away from the limiting rod (274), the moving block (273) is located between the two pushing plates (275) and at the top of the pushing plates (275), the pushing plates (275) and the moving block (273) are both inclined surfaces on the opposite sides, the pushing plate (275) is located on the top of the sliding plate (276), the bottom of the sliding plate (276) is fixedly connected to a connecting spring (31), the bottom of the connecting spring (31) is fixedly mounted to the inner wall of the bottom of the fixing groove, and the connecting spring (31) is located between the fixing rod (277) and the limiting rod (274).

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