Insecticidal composition containing amide insecticide and application thereof

Abstract

The invention belongs to the technical field of pesticide disinfestation, and discloses an insecticidal composition containing amide insecticides and application thereof.The active ingredients of the insecticidal composition comprise an active ingredient A and an active ingredient B. The active ingredient A is a compound shown in the formula I: # imgabs0 #, and the active ingredient B is the amide insecticides. The amide pesticide is any one of tolfenpyrad, cyhalodiamide, tetrachlorantraniliprole, polyflubendiamide, thiotraniliprole and thiodicyclaniliprole, and the compound pesticide is a compound of the following components in parts by weight; the mass ratio of the active component A to the active component B is (1: 40)-(40: 1). According to the insecticidal composition, the insecticidal effect is greatly improved, the utilization rate of the insecticide is increased, the development of insecticide resistance of pests is slowed down, and the service life of the insecticide is prolonged.

Description

Technical Field

[0001] The invention belongs to the technical field of pesticide insecticides and discloses an insecticide composition containing amide insecticides and application thereof. Background Art

[0002] Amide insecticides have diverse and novel structures, rich and unique mechanisms of action, and excellent and broad-spectrum insect repellent effects.

[0003] Tolfenpyrad, English common name: tolfenpyrad, CAS registration number: 129558-76-5, chemical name: 4-chloro-5-ethyl-2-methyl-N-[[4-(4-methylphenoxy)phenyl]methyl]pyrazole-3-carboxamide, its structural formula is as follows:

[0004]

[0005] Cyhalodiamide, English common name: cyhalodiamide, CAS registration number: 1262605-53-7, chemical name: 3-chloro-2-N-(2-cyanopropyl-2-yl)-1-N-[4-(1,1,1,2,3,3,3-heptafluoroprop-2-yl)-2-methylphenyl]benzene-1,2-dicarboxamide, its structural formula is as follows:

[0006]

[0007] Tetrachlorantraniliprole, English common name: tetrachlorantraniliprole, CAS registration number: 1104384-14-6, chemical name: 3-bromo-N-(2,4-dichloro-6-(methylcarbamoyl)phenyl)-1-(3,5-dichloropyridin-2-yl)-1H-pyrazole-5-carboxamide, its structural formula is as follows:

[0008]

[0009] Piperflanilide, English common name: piperflanilide, CAS registration number: 2615135-05-0, chemical name: N-(3-{[2-bromo-6-(difluoromethoxy)-4-(1,1,1,2,3,3,3-heptafluoropropyl-2-yl)phenyl]carbamoyl}-2-fluorophenyl)-2,2-difluoro-N-methyl-2H-1,3-benzodioxolane-5-carboxamide, its structural formula is as follows:

[0010]

[0011] Thiorantraniliprole, international common name: tiorantraniliprole, CAS registration number: 1442448-92-1, chemical name: 5-bromo-2-(3-chloropyridin-2-yl)-N-[2,4-dichloro-6-(propan-2-ylaminomethylsulfonyl)phenyl]pyrazole-3-carboxamide, its structural formula is as follows:

[0012]

[0013] Pioxaniliprole, international common name: pioxaniliprole, CAS registration number: 2368920-61-8, chemical name: N-[2-(tert-butylcarbamoyl)-4-chloro-6-methylphenyl]-1-(3-chloropyridin-2-yl)-3-[(1,1-dioxy-1λ 6 -thietan-3-yl)oxy]-1H-pyrazole-5-carboxamide, the structural formula of which is shown below:

[0014]

[0015] Excessive use of pesticides can easily lead to pests developing resistance, resulting in ineffective pesticide application. Among them, amide insecticides are new and highly effective insecticides used in recent years in my country to control major pests such as the striped stem borer, rice leaf roller, and diamondback moth on crops such as rice and vegetables. They are highly effective, low toxic, and require a small amount of use. Since entering the Chinese market, they have been sought after. However, it cannot be ignored that in recent years, due to continuous and large-scale use for many years, many pests in Jiangsu, Jiangxi, Hunan, Guangdong, Yunnan and other places have developed a certain resistance to amide insecticides. Summary of the invention

[0016] In order to solve the above problems existing in the prior art, the present invention reasonably compounded the compound shown in formula I with amide insecticides such as tolfenpyrad, cyhalodiamide, tetrachlorantraniliprole, piperflanilide, tiorantraniliprole and pioxaniliprole, and provided an insecticidal composition containing amide insecticides. The insecticidal composition has excellent control effect on plant pests, obvious synergistic effect, reduces the dosage of pesticides, and significantly slows down the development of pest resistance.

[0017] In order to achieve the above object, the present invention adopts the following technical scheme: an insecticide composition containing an amide insecticide, wherein the active ingredients of the insecticide composition include active ingredient A and active ingredient B, and the active ingredient A is a compound represented by formula I:

[0018] The active ingredient B is an amide insecticide, and the amide insecticide is any one of tolfenpyrad, cyhalodiamide, tetrachlorantraniliprole, piperflanilide, tiorantraniliprole, and pioxaniliprole; the mass ratio of the active ingredient A to the active ingredient B is 1:40 to 40:1, or any value within the above numerical range.

[0019] Furthermore, the active ingredient B is tolfenpyrad, and the mass ratio of the active ingredient A to the active ingredient B is 1:27 to 32:1, or any value within the above numerical range;

[0020] The active ingredient B is cyhalodiamide, and the mass ratio of the active ingredient A to the active ingredient B is 1:23 to 28:1, or any value within the above numerical range;

[0021] The active ingredient B is tetrachlorantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:35 to 32:1, or any value within the above numerical range;

[0022] The active ingredient B is piperflanilide, and the mass ratio of the active ingredient A to the active ingredient B is 1:20 to 24:1, or any value within the above numerical range;

[0023] The active ingredient B is tiorantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:22 to 32:1, or any value within the above numerical range;

[0024] The active ingredient B is pioxaniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:25 to 32:1, or any value within the above numerical range.

[0025] Furthermore, the active ingredient B is tolfenpyrad, and the mass ratio of the active ingredient A to the active ingredient B is 1:18 to 16:1, or any value within the above numerical range;

[0026] The active ingredient B is cyhalodiamide, and the mass ratio of the active ingredient A to the active ingredient B is 1:15 to 20:1, or any value within the above numerical range;

[0027] The active ingredient B is tetrachlorantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:28 to 16:1, or any value within the above numerical range;

[0028] The active ingredient B is piperflanilide, and the mass ratio of the active ingredient A to the active ingredient B is 1:12 to 24:1, or any value within the above numerical range;

[0029] The active ingredient B is tiorantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:18 to 25:1, or any value within the above numerical range;

[0030] The active ingredient B is pioxaniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:15 to 32:1, or any value within the above numerical range.

[0031] Furthermore, the active ingredient B is tolfenpyrad, and the mass ratio of the active ingredient A to the active ingredient B is 1:9 to 8:1, or any value within the above numerical range;

[0032] The active ingredient B is cyhalodiamide, and the mass ratio of the active ingredient A to the active ingredient B is 1:15 to 10:1, or any value within the above numerical range;

[0033] The active ingredient B is tetrachlorantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:16 to 8:1, or any value within the above numerical range;

[0034] The active ingredient B is piperflanilide, and the mass ratio of the active ingredient A to the active ingredient B is 1:10 to 16:1, or any value within the above numerical range;

[0035] The active ingredient B is tiorantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:18 to 14:1, or any value within the above numerical range;

[0036] The active ingredient B is pioxaniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:15 to 24:1, or any value within the above numerical range.

[0037] Furthermore, in addition to the active ingredients, the insecticide composition also includes other pesticide-acceptable adjuvants, and the adjuvants are selected from one or more of dispersants, wetting agents, emulsifiers, stabilizers, antifreeze agents, defoaming agents, preservatives, thickeners, solvents, organic acids, and dispersion media.

[0038] Furthermore, the formulation of the insecticide composition is one or more of emulsifiable concentrate, microemulsion, soluble liquid, suspension, aqueous solution, aqueous emulsion, ultra-low volume liquid, dispersible oil suspension, water-dispersible granules or wettable powder.

[0039] The invention also discloses the use of the insecticide composition in preventing and controlling plant pests.

[0040] Furthermore, the insecticidal composition of the present invention has obvious synergistic effect on the following lepidopteran pests: Plutella xylostella, diamondback moth, Polychrosis viteana (grape berry moth), Prays endocarpa, Prays oleae (olive moth), Pseudaletia spp. (snoctuids), Pseudaletia unipunctata (armyworm), Pseudoplusia includes (soybean looper), Rachiplusia nu, Scirpophaga incertulas, Sesamia spp. (stemborers), Sesamia inferens (pink ricestemworm). borer), Sesamia nonagrioides, Setora nitens, Sitotroga cerealella (Angoumois grain moth), Sparganothis pilleriana, Spodoptera spp. (snooper moth), Spodoptera exigua (beet armyworm), Spodoptera fugiperda (fallarmyworm), Adoxophyes spp., Adoxophyes orana, Agrotis spp.) (cutworm), Agrotis ipsilon (black cutworm), Alabama argillacea, Amorbia cuneana, Amyelosis transitella (navel orangeworm), Anarsia lineatella (peach twig borer), Anomis sabulifera (jute looper), Anticarsia gemma talis (velvet bean pilla r), Archips argyrospila (fruit tree leaf roller), Archips rosana (rose leaf roller), Argyrotaenia spp. (tortricid moths), Argyrotaenia citrana, Autographa gamma, Bonagota cranaodes, Borbo cinnara, Calopteris spp. (leaf miners), Capua reticulana, Carposina niponensis (peach fruit moth), Chilo spp., Chlumetia transversa (mango shoot borer), Choristoneura rosaceana (obliquebanded leafroller), Chrysodeixis spp., Cnaphalocerus medinalis (grass leafroller), Colias spp., Conpomorpha cramerella, Cossus cossus, Crambus spp.) (Sod webworms), Cydia funebrana (plum fruit moth), Cydia molesta (oriental fruit moth), Cydia nignicana (pea moth), Cydia pomonella, Darna diducta, Diaphania spp. (stem borers), Diatraea spp. (stalk borers), Diatraea spp. (sugarcane borer), Diatraea graniosella (southwester corn borer), Earias spp. (cotton bollworms), Earias spp. (Earias spp.) insulata (Egyptian bollworm), Earias vitella (rough northern bollworm), Ecdytopopha aurantianum, Elasmopalpus lignosellus (lesser cornstalk borer), Ephestia spp. (flour moths), Ephestia cautella (almond moth), Ephestia elutella (tobbaco moth), Ephestia kuehniella (Mediterranean flour moth), Epimeces spp., Epinotia aporema, Erionota thrax (banana skipper), Eupoecilia ambiguella), Euxoaauxiliaris (army cutworm), Feltia spp., Gortyna spp.) (stem borers), Grapholita molesta (oriental fruit moth), Hedylepta indicate, bean leafwebber, Helicoverpa sp p. (noctuids), Helicover paarmigera, Helicoverpa zea, Heliothis spp. (noctuids), Heliothis virescens, tobacco budworm, Hellula undalis (cabbage webworm), Indarbela spp., root borers, Keiferia lycopersicella, (tomato pinworm, Leucino desorbonalis (eggplant fruit borer), borer), Leucoptera malifoliella, Lithocollectis spp., Lobesia botrana (grape fruit moth), Loxagrotis spp. (noctuid armyworm), Loxagrotis albicosta (western bean cutworm), Lymantria dispar (gypsy moth), Lyonetia clerkella (apple leaf miner), Mahasena corbetti (oil palm bagworm), Malacosoma spp.)(tent caterpillars), Mamestra brassicae(cabbage armyworm), Maruca testulalis, Metisa plana, Mythimna unipuncta(true armyworm), Neoleucinodes elegantalis(small tomato borer), Operophthera brumata(winter moth), Ostrinia nubilalis(European corn borer), Pandemiscerasana, common currant tortrix, Pandemis heparana(brown apple tortrix), Papilio demodocus, Pectinophoragossypiella(pink bollworm), Peridroma species(Peridroma spp.) (cutworm), Peridroma saucia (variegated cutworm), Perileucoptera coffeella (white coffee leafminer), Phthorimaea operculella (potato tuber moth), Phyllocnisitis citrella, Phyllonorycter spp. (leafminers), Pieris rapae (imported cabbageworm), Plathypena scabra, Plodia interpunctella (Indian meal moth), Spodoptera oridania (southern armyworm), Synanthedon spp.)(root borers), Thecla basilides, Thermisia gemmatalis, Tineola bisselliella (webbing clothes moth), Trichoplusia ni (pigworm), Tuta absoluta, Yponomeuta spp., Zeuzera coffeae (redbranch borer), and Zeuzera pyrina (leopard moth).

[0041] In particular, the insecticide composition of the present invention has an obvious synergistic effect on the lepidopteran pests such as cotton bollworm, Spodoptera litura, rice stem borer, diamondback moth and cabbage worm, and has an excellent control effect.

[0042] Furthermore, the insecticide composition is applied to pests and the medium where the pests occur.

[0043] In order to obtain the desired insecticidal effect, the dosage of the insecticidal composition varies depending on various factors, such as the crop to be protected, the type of pest, the degree of infection, climatic conditions, application site, application method, dosage form used, etc.

[0044] The beneficial effects of the present invention are as follows:

[0045] 1) The present invention rationally compounds the insecticide compositions with different action mechanisms, greatly improves the insecticidal effect of amide insecticides, has a significant synergistic effect, improves the utilization rate of the agents, and reduces environmental pollution;

[0046] 2) The insecticide composition of the present invention can significantly delay the development of insecticide resistance, reduce production costs, and extend the service life of a single agent. DETAILED DESCRIPTION

[0047] In order to make the technical solutions, objectives and advantages of the present invention more clearly understood, the present invention is described with the following specific embodiments, but the present invention can be implemented in various forms and should not be limited by the embodiments described herein.

[0048] Preparation Example:

[0049] Preparation Example 1: 20% Formula I compound·Tolfenpyrad suspension (1:9)

[0050] Formula: 2% compound of formula I, 18% tolfenpyrad, 2% sodium lauryl sulfate, 3% sorbitan oleate polyoxyethylene ether, 4% tristyrylphenol ethoxylate phosphate, 0.25% xanthan gum, 1% magnesium aluminum silicate, 5% glycerol, 0.01% potassium benzoate, 0.5% silicone oil, and deionized water to make up the balance;

[0051] Preparation method: According to the formula ratio, the active ingredients, surfactants and other functional additives are placed in a reactor in sequence, water is added to mix evenly, and the suspension product is obtained by high-speed shearing, wet sand grinding, and finally homogenization filtration.

[0052] Preparation Example 2: 25% Formula I compound·Tolfenpyrad water dispersible granules (2:3)

[0053] Formula: 10% compound of formula I, 15% tolfenpyrad, 6% lignin sulfonate, 6% sodium alkyl polyoxyethylene ether sulfonate, 3% sodium lauryl sulfate, 5% white carbon black, 25% starch, and kaolin makes up the balance;

[0054] Preparation method: according to the proportions in the example, the active ingredient is added to the carrier, and a surfactant and other functional additives are added thereto, mixed, and after air flow pulverization, 10-25% of water is added, and then kneading, granulation, drying, and sieving are performed to obtain a water-dispersible granule product; or the pulverized powder is sprayed with water in a boiling granulator, granulated, dried, and then sieved to obtain the product.

[0055] Preparation Example 3: 18% Formula I compound·Tolfenpyrad emulsifiable concentrate (7:2)

[0056] Formula: 14% compound of formula I, 4% tolfenpyrad, 2% antioxidant BHT, 15% DMF, 12% castor oil polyoxyethylene ether, 2% calcium dodecylbenzene sulfonate, 20% propylene carbonate, and xylene makes up the balance;

[0057] Preparation method: according to the formula ratio, the measured active ingredients, solvents and co-solvents are added into a mixing kettle and stirred to dissolve, then an emulsifier is added, the remaining amount is supplemented with the remaining solvent, and the mixture is stirred evenly in a stirring kettle, and the desired emulsifiable concentrate is obtained after filtering.

[0058] Preparation Example 4: 4.5% Formula I compound·Tolfenpyrad microemulsion (8:1)

[0059] Formula: 4% compound of formula I, 0.5% tolfenpyrad, 2% antioxidant BHT, 15% xylene, 20% cyclohexanone, 12% tristyrylphenol polyoxyethylene ether polyoxypropylene ether, 6% EO-PO block copolymer, 2% fatty alcohol polyoxyethylene ether sulfate, 5% propylene glycol, 0.15% organosilicon defoamer, and deionized water to make up the balance;

[0060] Preparation method: After the active ingredient is completely dissolved in the solvent according to the formula ratio, an emulsifier is added to prepare an oil phase, and a dispersant, deionized water, etc. are added and stirred evenly to prepare an aqueous phase; the oil phase is added to the aqueous phase and stirred evenly, and high-speed shearing is performed until the particle size meets the requirements, and a defoaming agent is added and stirred evenly to obtain a microemulsion product.

[0061] Preparation Example 5: 16% Formula I compound·Cyantraniliprole dispersible oil suspension (1:15)

[0062] Formula: 1% compound of formula I, 15% chloranilamide, 2% naphthalenesulfonate formaldehyde condensate, 3% Guerbet alcohol polyoxyethylene ether, 10% triphenol polyoxyethylene ether, 3% ethylene glycol oxyethylene polyoxypropylene ether, 2% calcium dodecylbenzene sulfonate, 1% silicon dioxide, 1% organic bentonite, and methyl oleate makes up the balance;

[0063] Preparation method: According to the formula ratio, the active ingredients, surfactants and other functional additives are placed in the reactor in sequence, oil is added and mixed evenly, and the dispersible oil suspension product is obtained by high-speed shearing, wet sand grinding, and finally homogenization filtration.

[0064] Preparation Example 6: 24% Formula I compound·Cyantraniliprole suspension (2:1)

[0065] Formula: 16% compound of formula I, 8% chlorfluanid, 1% alkylaryl polyoxyethylene ether polyoxypropylene ether, 5% tristyrylphenol ethoxylate phosphate, 1% sodium lignin sulfonate, 3% sodium octylphenol polyoxyethylene ether sulfonate, 0.25% xanthan gum, 5% ethylene glycol, 0.1% sodium sorbate, 0.5% silicone oil, and deionized water to make up the balance;

[0066] Preparation method: Same as Preparation Example 1.

[0067] Preparation Example 7: 24% Formula I compound·Cyantraniliprole water dispersible granules (5:1)

[0068] Formula: 20% compound of formula I, 4% cyfluthrin, 8% succinate sulfonate, 2% lakai powder BX, 5% sodium polycarboxylate, 3% white sugar, kaolin makes up the balance;

[0069] Preparation method: Same as Preparation Example 2.

[0070] Preparation Example 8: 33% Formula I compound·Cyantraniliprole wettable powder (10:1)

[0071] Formula: 30% compound of formula I, 3% cypermethrin, 3% fatty alcohol ethylene oxide-propylene oxide copolymer, 6% sodium lignin sulfonate, 10% dispersant NNO, 2% opening powder BX, 6% white carbon black, and kaolin makes up the balance;

[0072] Preparation method: The active ingredients, dispersants, wetting agents and fillers are mixed according to the formula ratio, uniformly stirred in a stirring kettle, and pulverized and mixed uniformly for multiple times by a jet mill to prepare the wettable powder of the composition of the present invention.

[0073] Preparation Example 9: 27% Formula I compound·tetrachlorantraniliprole suspension (1:1)

[0074] Formula: 13.5% compound of formula I, 13.5% tetrachlorantraniliprole, 2% isomeric tridecanol polyoxyethylene ether, 2% ethylene glycol oxyethylene polyoxypropylene ether, 3% styrene phenol polyoxyethylene ether sulfate, 1% sodium salt of polycarboxylate, 1.5% magnesium aluminum silicate, 0.1% carboxyethyl cellulose, 1% kason, 5% ethylene glycol, 0.25% silicone oil, and deionized water to make up the balance;

[0075] Preparation method: Same as Preparation Example 1.

[0076] Preparation Example 10: 35% Formula I compound·tetrachlorantraniliprole water dispersible granules (1:4)

[0077] Formula: 7% compound of formula I, 28% tetrachlorantraniliprole, 3% sodium salt of polycarboxylate, 4% naphthalenesulfonate formaldehyde condensate, 12% calcium lignin sulfonate, 2% fatty alcohol polyoxyethylene ether sulfate, 10% ammonium sulfate, and starch makes up the balance.

[0078] Preparation method: Same as Preparation Example 2.

[0079] Preparation Example 11: 18% Formula I compound·tetrachlorantraniliprole dispersible oil suspension (8:1)

[0080] Formula: 16% compound of formula I, 2% tetrachlorantraniliprole, 5% sorbitan oleate polyoxyethylene ether, 8% castor oil polyoxyethylene ether, 2% calcium dodecylbenzene sulfonate, 2% sodium salt of polycarboxylate, 1% organic bentonite, and soybean oil makes up the balance;

[0081] Preparation method: Same as Preparation Example 3.

[0082] Preparation Example 12: 21% Formula I compound·polyflubendiamide suspension (1:6)

[0083] Formula: 3% compound of formula I, 18% polyflubenzuronamide, 2% ethylene glycol oxyethylene polyoxypropylene ether, 1% naphthalene sulfonate formaldehyde condensate, 3% tristyrylphenol ethoxylate phosphate, 3% castor oil polyoxyethylene ether, 0.2% xanthan gum, 1% magnesium aluminum silicate, 5% ethylene glycol, 0.2% sodium benzoate, 0.5% silicone oil, and deionized water to make up the balance;

[0084] Preparation method: Same as Preparation Example 1.

[0085] Preparation Example 13: 20% Formula I compound·polyflubendiamide water dispersible granules (3:2)

[0086] Formula: 12% compound of formula I, 8% polyflubendiamide, 3% wetting agent EFW, 7% naphthalenesulfonate formaldehyde condensate, 5% sodium alkyl polyoxyethylene ether sulfonate, 5% white carbon black, 20% starch, and kaolin makes up the balance;

[0087] Preparation method: Same as Preparation Example 2.

[0088] Preparation Example 14: 30% Formula I compound·polyflubendiamide wettable powder (5:1)

[0089] Formula: 25% compound of formula I, 5% polyflubendiamide, 2% sodium lauryl sulfate, 5% polyoxyethylene styrene phenol sulfate, 5% tea saponin, 2% sodium alginate, 10% light calcium carbonate, and kaolin makes up the balance;

[0090] Preparation method: Same as Preparation Example 8.

[0091] Preparation Example 15: 22% Formula I compound·sulfuronamide suspension (1:10)

[0092] Formula: 2% compound of formula I, 20% thiobenzamide, 5% tristyrylphenol polyoxyethylene ether polyoxypropylene ether, 5% arylphenol polyoxyethylene ether phosphate, 2% sodium polycarboxylate, 0.25% xanthan gum, 5% propylene glycol, 0.1% sodium benzoate, 0.5% silicone oil, and deionized water to make up the balance;

[0093] Preparation method: Same as Preparation Example 1.

[0094] Preparation Example 16: 35% Formula I compound·sulfuronamide water dispersible granules (5:2)

[0095] Formula: 25% compound of formula I, 10% thiobencarb, 2% sodium dodecyl sulfate, 10% sodium lignin sulfonate, 5% naphthalene sulfonate formaldehyde condensate, 10% ammonium sulfate, and kaolin makes up the balance;

[0096] Preparation method: Same as Preparation Example 2.

[0097] Preparation Example 17: 8% Formula I compound·sulfuronamide emulsifiable concentrate (7:1)

[0098] Formula: 7% compound of formula I, 1% thiobenzamide, 15% propylene glycol methyl ether, 10% tristyrylphenol polyoxyethylene ether, 2% calcium dodecylbenzene sulfonate, 15% DMF, 18% cyclohexanone, and methyl oleate makes up the balance;

[0099] Preparation method: according to the formula ratio, the active ingredient, solvent and co-solvent are added into a mixing kettle and stirred to dissolve, then an emulsifier is added, and the balance is supplemented with the remaining solvent, and the mixture is stirred evenly in a stirring kettle, and the desired emulsifiable concentrate is obtained after filtering.

[0100] Preparation Example 18: 22% Formula I compound·Thiocyclam suspension (5:6)

[0101] Formula: 10% compound of formula I, 12% thiocyclanil, 6% glycerol fatty acid ester polyoxyethylene ether, 5% tristyrylphenol ethoxylate phosphate, 2% naphthalenesulfonate, 0.25% xanthan gum, 5% glycerol, 0.15% sodium sorbate, 0.5% silicone oil, and deionized water to make up the balance;

[0102] Preparation method: Same as Preparation Example 1.

[0103] Preparation Example 19: 30% Formula I compound·Thiocyclam water dispersible granules (1:4)

[0104] Formula: 6% compound of formula I, 24% thiocyclamide, 2% sodium dodecyl sulfate, 8% naphthalenesulfonate formaldehyde condensate, 6% polycarboxylate sodium salt, 8% ammonium sulfate, and kaolin makes up the balance;

[0105] Preparation method: Same as Preparation Example 2.

[0106] Preparation Example 20: 8% Formula I compound·sulfuronamide emulsifiable concentrate (7:1)

[0107] Formula: 7% compound of formula I, 1% thiobenzamide, 15% propylene glycol methyl ether, 10% oleic acid polyoxyethylene ether, 2% calcium dodecylbenzene sulfonate, 12% DMF, 20% cyclohexanone, and methyl oleate makes up the balance;

[0108] Preparation method: according to the formula ratio, the active ingredient, solvent and co-solvent are added into a mixing kettle and stirred to dissolve, then an emulsifier is added, and the balance is supplemented with the remaining solvent, and the mixture is stirred evenly in a stirring kettle, and the desired emulsifiable concentrate is obtained after filtering.

[0109] Indoor biological activity test:

[0110] Example 1: Indoor biological activity test of the composite composition against rice stem borer

[0111] Test basis: The test refers to NY / T 1154.10-2008 "Guidelines for Indoor Bioassay Tests of Pesticides - Insecticides Part 10: Artificial Feed Mixing Method".

[0112] Biological test materials: Rice stem borer, third-instar larvae that were continuously raised indoors and had consistent physiological states were selected.

[0113] Test agents: tolfenpyrad, chlorfluanid, tetrachlorantraniliprole, polyfluanid, thiobencarb, thiocyclanil, and the original drug of the compound of formula I.

[0114] Preparation of medicine: dissolve the above raw medicine in a suitable organic solvent to prepare a mother solution, and use Tween-80 aqueous solution to prepare 5 series of mass concentrations according to the equal ratio method.

[0115] Test method: Evenly mix an appropriate amount of diluted drug solution into the prepared artificial feed, pour it into 12-well plates while it is hot and cool it down, then inoculate one test insect into each well. Repeat each treatment 4 times, with 20 test insects in each repetition, and set a treatment without drug (containing organic solvents) as a blank control.

[0116] Feeding and observation: The treated test insects were placed in a temperature of (25±1)℃, a relative humidity of 60% to 80%, and a photoperiod of L:D=(16:8)h for feeding and observation. After 48h of treatment, the death of the test insects was checked, and the total number of insects and the number of dead insects were recorded respectively.

[0117] Calculation method:

[0118] Based on the survey data, the mortality rate of each treatment was calculated.

[0119] Calculate as follows:

[0120]

[0121] Where:

[0122] P——mortality rate, in percentage (%);

[0123] K——indicates the number of dead insects, in units of heads;

[0124] N——represents the total number of insects treated, in heads.

[0125]

[0126] Where:

[0127] P 1 ——Adjusted mortality rate, expressed as percentage (%);

[0128] P t ——Treatment mortality rate, expressed as percentage (%);

[0129] P 0 ——Blank control mortality rate, in percentage (%).

[0130] If the control mortality rate is less than 5%, no correction is required; if the control mortality rate is between 5% and 20%, correction should be made according to the correction mortality formula; if the control mortality rate is greater than 20%, the test needs to be repeated.

[0131] The DPS statistical analysis system was used to analyze the toxicity regression equation, correlation coefficient and LC 50 Value, to evaluate the activity of the test agent on the biological test material.

[0132] The co-toxicity coefficient (CTC value) of the mixture is calculated as follows:

[0133]

[0134] Where:

[0135] ATI——Actual Toxicity Index of Mixture;

[0136] S——LC of standard pesticide 50 , the unit is milligrams per liter (mg / L);

[0137] M——LC of the mixture 50 , the unit is milligrams per liter (mg / L).

[0138] TTI=TI A ×P A +TI B ×P B

[0139] Where:

[0140] TTI – Theoretical Toxicity Index of Mixtures;

[0141] TI A ——A: toxicity index of the agent;

[0142] P A ——The percentage of agent A in the mixture, in percentage (%);

[0143] TI B ——Toxicity index of agent B;

[0144] P B ——The percentage of agent B in the mixture, in percentage (%).

[0145]

[0146] Where:

[0147] CTC – Co-toxicity coefficient;

[0148] ATI——Actual Toxicity Index of Mixture;

[0149] TTI - Theoretical Toxicity Index of Mixture.

[0150] The co-toxicity coefficient of the combination CTC≥120 shows a synergistic effect; CTC≤80 shows an antagonistic effect; 80<CTC<120 shows an additive effect.

[0151] The indoor test results are shown in the following table:

[0152] Table 1 Results of indoor biological activity test of compound I and tolfenpyrad against Chilo suppressalis

[0153]

[0154] From the results of the indoor biological activity test in Table 1, it can be seen that the compound of formula I and tolfenpyrad in a suitable mass ratio show excellent control effects on the rice stem borer. The mass ratio of the compound of formula I to tolfenpyrad is 1:27-32:1, and the co-toxicity coefficient to the rice stem borer is greater than 120, showing a synergistic effect; the mass ratio of the compound of formula I to tolfenpyrad is 1:18-16:1, and the co-toxicity coefficient is greater than 130, showing a significant synergistic effect; the mass ratio of the compound of formula I to tolfenpyrad is 1:9-8:1, and the co-toxicity coefficient is greater than 140, showing a significant synergistic effect.

[0155] Table 2 Results of indoor biological activity test of compound of formula I and cyfluthrin against Chilo suppressalis

[0156]

[0157] From the results of the indoor biological test in Table 2, it can be seen that the compound of formula I and chlorfluanid in a suitable mass ratio show excellent control effects on rice stem borer. The mass ratio of the compound of formula I to chlorfluanid is 1:23-28:1, and the co-toxicity coefficient to rice stem borer is greater than 120, showing a synergistic effect; the mass ratio of the compound of formula I to chlorfluanid is 1:15-20:1, the co-toxicity coefficient is greater than 130, and the synergistic effect is obvious; the mass ratio of the compound of formula I to chlorfluanid is 1:15-10:1, the co-toxicity coefficient is greater than 140, and the synergistic effect is significant.

[0158] Table 3 Indoor biological activity test results of compound I and tetrachlorantraniliprole against Chilo suppressalis

[0159]

[0160] From the results of the indoor biological test in Table 3, it can be seen that the compound of formula I and tetrachlorantraniliprole in a suitable mass ratio show excellent control effect on the rice stem borer. The mass ratio of the compound of formula I to tetrachlorantraniliprole is 1:35-32:1, and the co-toxicity coefficient to the rice stem borer is greater than 120, showing a synergistic effect; the mass ratio of the compound of formula I to tetrachlorantraniliprole is 1:28-16:1, and the co-toxicity coefficient to the rice stem borer is greater than 130, and the synergistic effect is obvious; the mass ratio of the compound of formula I to tetrachlorantraniliprole is 1:16-8:1, and the co-toxicity coefficient to the rice stem borer is greater than 140, and the synergistic effect is significant.

[0161] Table 4 Indoor biological activity test results of compound I and polyflubendiamide against rice stem borer

[0162]

[0163] From the results of the indoor biological test in Table 4, it can be seen that the compound of formula I and polyflubencarbamide in a suitable mass ratio show excellent control effects on rice stem borer. The mass ratio of the compound of formula I to polyflubencarbamide is 1:20-24:1, the co-toxicity coefficient is greater than 120, and it shows a synergistic effect; the mass ratio of the compound of formula I to polyflubencarbamide is 1:12-24:1, the co-toxicity coefficient is greater than 130, and the synergistic effect is obvious; the mass ratio of the compound of formula I to polyflubencarbamide is 1:10-16:1, the co-toxicity coefficient is greater than 140, and the synergistic effect is significant.

[0164] Table 5 Indoor biological activity test results of compound I and thiobencarb against Chilo suppressalis

[0165]

[0166] From the results of the indoor biological test in Table 5, it can be seen that the compound of formula I and thiobencarbamide in a suitable mass ratio exhibit excellent control effects on the rice stem borer. The mass ratio of the compound of formula I to thiobencarbamide is 1:22-32:1, the co-toxicity coefficient is greater than 120, and it exhibits a synergistic effect on the rice stem borer; the mass ratio of the compound of formula I to thiobencarbamide is 1:18-25:1, the co-toxicity coefficient is greater than 130, and the synergistic effect is obvious; the mass ratio of the compound of formula I to thiobencarbamide is 1:18-14:1, the co-toxicity coefficient is greater than 140, and the synergistic effect is significant.

[0167] Table 6 Results of indoor biological activity test of compound I and thiocarb against Chilo suppressalis

[0168]

[0169] From the results of the indoor biological activity test in Table 6, it can be seen that the compound of formula I and thiocarbamide are compounded in an appropriate mass ratio, and excellent control effects are shown on the rice stem borer. The mass ratio of the compound of formula I to thiocarbamide is 1:25-32:1, and the co-toxicity coefficient to the rice stem borer is greater than 120, showing a synergistic effect; the mass ratio of the compound of formula I to thiocarbamide is 1:15-32:1, and the co-toxicity coefficient is greater than 130, and the synergistic effect is obvious; the mass ratio of the compound of formula I to thiocarbamide is 1:15-24:1, and the co-toxicity coefficient is greater than 140, and the synergistic effect is significant.

[0170] Example 2: Field test on efficacy of controlling rice stem borer

[0171] Experimental area: Qinghe Village, Jingkou Township, Nanchang County, Nanchang City, Jiangxi Province. Rice is planted all year round in the experimental field. The experimental object is rice stem borer. The rice variety is Huanghuazhan. The experimental field has convenient irrigation and drainage, and the soil fertility is medium.

[0172] Experimental method: The experiment set up 14 treatments, 13 pesticide treatments, and water spraying as a blank control. Each treatment was repeated 4 times, and the random block arrangement was carried out. Each plot area was 50m 2 , set up a 0.5m isolation zone between the plots. Apply the pesticide during the peak hatching period of the Chilo suppressalis eggs, and there should be no rainfall on the day of application and 3 days after application. According to the concentration requirements of different pesticides, the weighed pesticides in each test plot are first stirred evenly in a small amount of water, and then added to the amount of water to prepare the solution in the plot. After the pesticide is diluted, use a 3WBD-18 backpack electric sprayer to add 600L / hm2 of water. 2 Afterwards, the whole rice plant was sprayed with pesticide evenly, and the pesticide was applied only once. The control plot was sprayed with the same amount of water. No other pesticides were applied during the experiment, and other agricultural operations were managed according to normal production methods.

[0173] Experimental investigation: 21 days after application, parallel jumping sampling was carried out at 5 points in each plot, and 5 clumps of rice were investigated in each plot to investigate the number of dead cores and the total number of plants.

[0174] Calculation method of drug efficacy:

[0175]

[0176] The results of the field efficacy test are shown in the following table:

[0177] Table 7 Results of field trials on efficacy of control of rice stem borer

[0178]

[0179] Safety investigation: During the field test, no pesticide damage occurred in any treatment group, and no adverse effects were found on the surrounding environment and other beneficial organisms in the test area, indicating that the test agents were safe for rice growth at the doses provided.

[0180] The results show (see Table 7) that the quick-acting and long-lasting effects of the combined preparations in controlling the rice stem borer are significantly better than those of other agents. The 22% Formula I compound·thiocyclam suspension (5:6) has the highest control effect of 96.00%.

[0181] Example 3: Field efficacy test for controlling fall armyworm

[0182] Test location: corn field in Juyang Village, Gongji Town, Taihe County, Fuyang City, Anhui Province. The soil of the test field is sandy loam, the ground is flat, the soil fertility is medium, and the drainage and irrigation are convenient. The corn planting spacing is 20cm, and one grain is sown in a hole. The planting management is the same as the local corn planting management.

[0183] Experimental design: The experiment adopted randomized block arrangement, with a total of 14 treatments, 4 replicates for each treatment, and a plot area of ​​45m 2 .

[0184] Test method: The corn was in the trumpet stage when the test started. The pesticide was applied according to the test design, using a backpack sprayer. The amount of pesticide applied was the amount of active ingredient, and the water consumption for each treatment was 450L / hm2. 2 The cultivation and water and fertilizer management conditions in all experimental plots were uniform and consistent.

[0185] Experimental investigation: Diagonal sampling method was used for investigation. Five points were investigated in each plot, with 20 plants at each point, for a total of 100 plants. All investigated plants were marked. The insect population base was investigated before spraying. The number of live insects was investigated 3, 7, and 14 days after spraying. The insect population reduction rate and control effect were calculated according to the following formula.

[0186] Calculation method of drug efficacy:

[0187]

[0188]

[0189] The results of the field efficacy test are shown in the table below:

[0190] Table 8 Results of field efficacy test on control of fall armyworm

[0191]

[0192] The results of the field efficacy test show that the insecticide composition of the present invention has a good control effect on fall armyworm. Preparation Example 7: 24% Formula I compound·Cyfluanid water dispersible granules (5:1), Preparation Example 14: 30% Formula I compound·Polyfluanid wettable powder (5:1), Preparation Example 2: 25% Formula I compound·Tolufenamide water dispersible granules (2:3), Preparation Example 20: 8% Formula I compound·Thiocyclanil emulsifiable concentrate (7:1), Preparation Example 17: 8% Formula I compound·Thiocyclanil emulsifiable concentrate (7:1), Preparation Example 9 : The control effects of 27% formula I compound·tetrachlorantraniliprole suspension (1:1) were 82.90%, 87.89%, 85.51%, 89.12%, 86.42% and 90.62% respectively 3 days after application, showing good quick-acting property; 14 days after application, the efficacy of each compound preparation was 90.05%, 90.23%, 87.52%, 93.22%, 93.23% and 96.61%, with a long lasting effect.

[0193] In summary, through indoor toxicity determination and field efficacy test, it can be seen that the insecticidal composition of the present invention has a good control effect on lepidopteran pests, is safe for target crops, has significant control effect, and is superior to a single agent in delaying the development of resistance and prolonging the lasting effect.

[0194] Although the application describes specific embodiments in detail by means of examples, the disclosure of the application may adopt various modifications and alternative forms. However, it should be understood that the disclosure of the application is not limited to the disclosed specific forms. On the contrary, the disclosure of the application covers all modifications, equivalents and alternative forms within the scope of the disclosure of the application, and the scope of the application is limited by the attached claims and their legal equivalents.

Claims

1. An insecticidal composition containing an amide insecticide, It is characterized in that The active ingredients of the insecticide composition include active ingredient A and active ingredient B, and the active ingredient A is a compound represented by formula I: The active ingredient B is an amide insecticide, and the amide insecticide is any one of tolfenpyrad, chlorfluanid, tetrachlorantraniliprole, polyfluanid, thiobencarb, and thiocyclanil; the mass ratio of the active ingredient A to the active ingredient B is 1:40 to 40:

1.

2. The insecticidal composition according to claim 1, It is characterized in that The active ingredient B is tolfenpyrad, and the mass ratio of the active ingredient A to the active ingredient B is 1:27 to 32:1; The active ingredient B is chloranil, and the mass ratio of the active ingredient A to the active ingredient B is 1:23 to 28:1; The active ingredient B is tetrachlorantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:35 to 32:1; The active ingredient B is polyflubendiamide, and the mass ratio of the active ingredient A to the active ingredient B is 1:20 to 24:1; The active ingredient B is thiobencarb, and the mass ratio of the active ingredient A to the active ingredient B is 1:22 to 32:1; The active ingredient B is thiocarb, and the mass ratio of the active ingredient A to the active ingredient B is 1:25 to 32:

1.

3. The insecticidal composition according to claim 2, It is characterized in that The active ingredient B is tolfenpyrad, and the mass ratio of the active ingredient A to the active ingredient B is 1:18 to 16:1; The active ingredient B is chloranil, and the mass ratio of the active ingredient A to the active ingredient B is 1:15 to 20:1; The active ingredient B is tetrachlorantraniliprole, and the mass ratio of the active ingredient A to the active ingredient B is 1:28 to 16:1; The active ingredient B is polyflubendiamide, and the mass ratio of the active ingredient A to the active ingredient B is 1:12 to 24:1; The active ingredient B is thiobencarb, and the mass ratio of the active ingredient A to the active ingredient B is 1:18 to 25:1; The active ingredient B is thiocarb, and the mass ratio of the active ingredient A to the active ingredient B is 1:15 to 32:

1.

4. The insecticidal composition according to claim 3, It is characterized in that The active ingredient B is tolfenpyrad, and the mass ratio of the active ingredient A to the active ingredient B is 1:9 to 8:1; The active ingredient B is chloranil, and the mass ratio of the active ingredient A to the active ingredient B is 1:15 to 10:1; The active ingredient B is tetrachlorvinphos, and the mass ratio of the active ingredient A to the active ingredient B is 1:16 to 8:1; The active ingredient B is polyflubendiamide, and the mass ratio of the active ingredient A to the active ingredient B is 1:10 to 16:1; The active ingredient B is thiobencarb, and the mass ratio of the active ingredient A to the active ingredient B is 1:18 to 14:1; The active ingredient B is thiocarb, and the mass ratio of the active ingredient A to the active ingredient B is 1:15 to 24:

1.

5. The insecticidal composition according to claim 1, It is characterized in that In addition to the active ingredients, the insecticide composition also includes other pesticide-acceptable adjuvants, which are selected from one or more of dispersants, wetting agents, emulsifiers, stabilizers, antifreeze agents, defoamers, preservatives, thickeners, solvents, organic acids, and dispersion media.

6. The insecticidal composition according to claim 1, It is characterized in that The preparation form of the insecticide composition is one or more of emulsifiable concentrate, microemulsion, soluble liquid, suspension, aqueous solution, water emulsion, ultra-low volume liquid, dispersible oil suspension, water dispersible granule or wettable powder.

7. Use of the insecticidal composition according to any one of claims 1 to 6 in controlling plant pests.

8. The use according to claim 7, It is characterized in that The plant pests are lepidoptera pests.

9. The use according to claim 8, It is characterized in that The lepidopteran pests are cotton bollworm, Spodoptera litura, rice borer, diamondback moth and cabbage looper.

10. The use according to claim 7, It is characterized in that The insecticide composition is applied to pests and the medium where the pests occur.

Images