Traditional Chinese medicine composition for preventing hair loss as well as preparation method, application and scalp preparation thereof

Abstract

The invention relates to the technical field of daily chemical products, and particularly provides a traditional Chinese medicine composition for preventing hair loss as well as a preparation method, application and a scalp preparation thereof. The traditional Chinese medicine composition for preventing hair loss is prepared from the following components in parts by mass: 10 to 30 parts of tilia latifolia flower extract, 30 to 80 parts of cacumen biotae extract, 10 to 20 parts of polygonum tinctorium herb extract and 5 to 30 parts of ginger extract. The traditional Chinese medicines are extracted by adopting a specific extraction method, and then the extracted traditional Chinese medicines are combined to obtain the traditional Chinese medicine composition for preventing alopecia, and the traditional Chinese medicine composition can improve the hair follicle environment and prevent alopecia, and in addition, the traditional Chinese medicine composition also can inhibit inflammation. Therefore, the traditional Chinese medicine composition disclosed by the invention is suitable for being applied to various scalp care cosmetics and has a good industrial application prospect.

Description

Technical Field

[0001] The invention relates to the technical field of daily chemical products, and more specifically to a Chinese medicine composition for preventing hair loss, a preparation method thereof, an application thereof, and a scalp preparation. Background Art

[0002] Hair loss refers to the phenomenon of hair falling out. The hair that falls out normally is the hair in the regression phase and the resting phase. Since the hair entering the regression phase and the hair entering the new growth phase are constantly in a dynamic balance, the normal amount of hair can be maintained. Under normal circumstances, the hair papilla in the hair follicle has abundant capillaries, which can absorb the nutrients necessary for hair growth from the blood to ensure the normal growth of hair; due to metabolism, about 50-100 hairs fall out every day, but it does not affect the overall amount of hair.

[0003] However, due to many reasons such as excessive secretion of sebaceous glands and clogged pores, the normal growth environment of hair will be destroyed, so that hair cannot grow normally, and serious hair loss and hair breakage will occur. Specifically, there are many reasons for hair loss. Genetics is often one of the main causes of hair loss; changes in hormone levels may cause hair loss, such as pregnancy, childbirth, menopause, etc. For modern people, with the accelerated pace of social life and increasing environmental pollution, more and more people are under high-intensity mental stress, overtime, staying up late, etc. for a long time, and long-term tension and stress may cause inflammation, which in turn affects the hair growth cycle and causes hair loss; in addition, stress can also lead to excessive sebum secretion, causing hair follicles to atrophy and cause hair loss, and low metabolic function of hair follicles and hair bulbs.

[0004] Therefore, improving inflammation and inhibiting excessive sebum secretion are the main measures to promote hair growth. At present, the drugs for preventing hair loss and promoting hair growth are mainly based on chemical substances, such as finasteride, aprelet, epristeride, dutasteride, ketoconazole and other western medicine ingredients, but western medicine ingredients are highly irritating and have great side effects, with a higher incidence of skin allergies and dandruff. Stopping the drug may make the hair loss problem more serious. Summary of the invention

[0005] In view of this, the purpose of the present invention is to provide a traditional Chinese medicine composition for preventing hair loss, and its preparation method, application, and scalp preparation. The traditional Chinese medicine composition for preventing hair loss of the present invention adopts a traditional Chinese medicine composition with low irritation and low toxicity to the human body as an active ingredient, which can achieve a better anti-hair loss effect.

[0006] In order to achieve the above object, the present invention adopts the following technical solutions:

[0007] A traditional Chinese medicine composition for preventing hair loss comprises, by weight: 10 to 30 parts of Tilia latifolia flower extract, 30 to 80 parts of Platycladus orientalis leaf extract, 10 to 20 parts of Polygonum indigofera extract, and 5 to 30 parts of ginger extract.

[0008] Tilia platyphyllos is a common deciduous tree belonging to the Malvaceae family, usually growing in forests in Europe and West Asia. The flowers of Tilia platyphyllos are yellow-green and have a sweet aroma. The flowers are gathered into umbels and bloom in summer. Tilia platyphyllos flower extracts are often used as raw materials for health products, cosmetics and medicines, and have multiple effects such as antioxidant and antibacterial.

[0009] Platycladus orientalis leaves refer to the leaves of Cryptomeria japonica, a plant of the Cupressaceae family, and are often used in traditional Chinese medicine or health foods. The medicinal value of Platycladus orientalis leaves mainly includes the following aspects: Clearing away heat and detoxifying: Platycladus orientalis leaves are believed by traditional Chinese medicine to have the effect of clearing away heat and detoxifying, and can be used to treat symptoms caused by external pathogens such as colds, fever, sore throat, etc.; Antibacterial and anti-inflammatory: Platycladus orientalis leaves contain some active ingredients, which have certain antibacterial and anti-inflammatory effects, and help prevent and treat infectious diseases.

[0010] Polygonum aviculare is a plant of the Polygonaceae family, also known as indigo, indigo seeds, etc. According to the Materia Medica, indigo can "fill the bone marrow, brighten the eyes and ears, benefit the five internal organs, regulate the six internal organs, open the joints, treat qi stagnation in the meridians, make people healthy and sleep less, and improve heart strength." Polygonum aviculare is a common Chinese medicinal material, used in food, health products and cosmetics, and has rich value.

[0011] Ginger (Zingiber officinale Roscoe) is a perennial herbaceous plant of the ginger family, and is widely used in traditional Chinese medicine. Ginger has a variety of effects and functions: Dispelling cold: Ginger has the effect of warming the yang and dispelling cold, and is often used to relieve cold symptoms caused by cold in the body; Promoting digestion: Ginger contains ingredients such as gingerol, which can stimulate the gastric mucosa, increase gastric juice secretion, and promote digestion; Anti-inflammatory and anti-inflammatory: Active ingredients such as curcumin in ginger have certain anti-inflammatory effects, which can relieve pain and discomfort caused by inflammation.

[0012] Preferably, the preparation method of the Tilia latifolia flower extract comprises:

[0013] The broad-leaved linden flower is crushed, mixed with an ethanol solution, extracted at 50-60° C. for 1-2 hours, concentrated under reduced pressure, and freeze-dried to obtain a broad-leaved linden flower extract;

[0014] The solid-liquid ratio of the broadleaf linden flower to the ethanol solution is 1:(10-25) g / mL;

[0015] In the ethanol solution, the mass fraction of ethanol is 45% to 60%; more preferably, the system after reduced pressure concentration is concentrated into an extract, 8 to 15 times the mass of butanediol of the extract is added, and a solubilizer is added according to actual needs, the solubilizer includes but is not limited to CO40; the extract is a thick extract with a water content of 15% to 30%.

[0016] In an embodiment of the present invention, the preparation method of the broad-leaved linden flower extract comprises: taking broad-leaved linden flower, crushing, adding 45wt% ethanol solution, the solid-liquid ratio of broad-leaved linden flower powder to ethanol solution is 1:10g / mL, extracting twice at 50-60°C, each time for 30 minutes, concentrating under reduced pressure, freezing the product at -18°C for 24 hours, and the conditions of sublimation and analytical drying are -10°C, 50Pa, 30°C, 20Pa, respectively, to obtain the broad-leaved linden flower extract.

[0017] Preferably, the method for preparing the Platycladus orientalis leaf extract comprises:

[0018] The Platycladus orientalis leaves are mixed with a solvent to obtain an extract, and the extract is subjected to ultrasonication, concentration and drying to obtain the Platycladus orientalis leaf extract.

[0019] Preferably, the solvent comprises an ethanol solution; in the ethanol solution, the mass fraction of ethanol is 45% to 60%; the concentrated system is concentrated into an extract, 8 to 15 times the mass of butanediol of the extract is added, and a solubilizer is added according to actual needs, the solubilizer includes but is not limited to CO40; the extract is a thick extract with a water content of 15% to 30%.

[0020] In an embodiment of the present invention, the method for preparing the Platycladus orientalis leaf extract comprises:

[0021] The Platycladus orientalis leaves were crushed, immersed in a 45wt% ethanol solution, and refluxed for extraction, with the solid-liquid ratio of Platycladus orientalis leaf powder and ethanol solution being 1:10 g / mL; reflux extraction was performed three times, each extraction time being 20 min, and the temperature being 50°C, to obtain an extract; the extract was ultrasonically treated at 100 W for 20 min, at a temperature of 50°C, and the supernatant was obtained by centrifugation to obtain an extract, which was concentrated under reduced pressure and dried at 80°C for 8 h to obtain a Platycladus orientalis leaf extract.

[0022] Preferably, the mass fraction of ethanol in the ethanol solution is 45% to 60%; the system after reduced pressure concentration is concentrated into an extract, 8 to 15 times the mass of butanediol of the extract is added, and a solubilizer is added according to actual needs, the solubilizer includes but is not limited to CO40; the extract is a thick extract with a water content of 15% to 30% or a dry extract with a water content of 5%.

[0023] Preferably, the method for preparing the Polygonum indigofera extract comprises:

[0024] The indigofera tinctoria is mixed with a solvent to obtain an extract, and the extract is concentrated and dried to obtain the indigofera tinctoria extract.

[0025] Preferably, the solvent comprises an ethanol solution; in the ethanol solution, the mass fraction of ethanol is 45% to 60%; the concentrated system is concentrated into an extract, 8 to 15 times the mass of butanediol of the extract is added, and a solubilizer is added according to actual needs, the solubilizer includes but is not limited to CO40; the extract is a thick extract with a water content of 15% to 30%.

[0026] In an embodiment of the present invention, the method for preparing the Polygonum indigofera extract comprises:

[0027] The indigofera was crushed, immersed in a 45wt% ethanol solution, and refluxed for extraction, with the solid-liquid ratio of the indigofera powder to the ethanol solution being 1:10 g / mL; the reflux extraction was performed three times, with each extraction time being 20 min and the temperature being 50°C to obtain an extract, which was concentrated under reduced pressure and dried at 80°C for 8 h to obtain the indigofera extract.

[0028] Preferably, the method for preparing the ginger extract comprises:

[0029] The ginger root is mixed with a solvent to obtain an extract, and the extract is concentrated and dried to obtain a ginger extract.

[0030] Preferably, the solvent comprises an ethanol solution; in the ethanol solution, the mass fraction of ethanol is 45% to 60%; the concentrated system is concentrated into an extract, 8 to 15 times the mass of butanediol of the extract is added, and a solubilizer is added according to actual needs, the solubilizer includes but is not limited to CO40; the extract is a thick extract with a water content of 15% to 30%.

[0031] In an embodiment of the present invention, the method for preparing the ginger extract comprises:

[0032] The ginger root was crushed, immersed in a 45wt% ethanol solution, and refluxed for extraction. The solid-liquid ratio of the ginger root powder to the ethanol solution was 1:15g / mL. The reflux extraction was performed 3 times, each time for 20min at a temperature of 50°C to obtain an extract, which was concentrated under reduced pressure and dried at 40°C for 20h to obtain a ginger extract.

[0033] Preferably, the Chinese medicine composition for preventing hair loss comprises, by weight: 20 parts of Tilia latifolia flower extract, 70 parts of Platycladus orientalis leaf extract, 20 parts of Polygonum indigofera extract, and 15 parts of ginger extract;

[0034] Alternatively, the Chinese medicine composition for preventing hair loss comprises, by weight: 25 parts of Tilia latifolia flower extract, 54 parts of Platycladus orientalis leaf extract, 18 parts of Polygonum indigofera extract, and 20 parts of ginger extract;

[0035] Alternatively, the Chinese herbal composition for preventing hair loss comprises, in parts by mass: 30 parts of Tilia latifolia flower extract, 39 parts of Platycladus orientalis leaf extract, 20 parts of Polygonum indigofera extract, and 30 parts of ginger extract.

[0036] The present invention also provides a method for preparing the Chinese medicine composition for preventing hair loss, comprising:

[0037] By weight, 10 to 30 parts of Tilia latifolia flower extract, 30 to 80 parts of Platycladus orientalis leaf extract, 10 to 20 parts of Polygonum indigofera extract and 5 to 30 parts of ginger extract are mixed to obtain a traditional Chinese medicine composition for preventing hair loss.

[0038] The present invention also provides application of the traditional Chinese medicine composition for preventing hair loss in inhibiting inflammatory factors.

[0039] Preferably, the inflammatory factors include TNF-α and / or IL-1β.

[0040] The present invention also provides a scalp preparation, comprising the Chinese medicine composition for preventing hair loss, and acceptable auxiliary materials.

[0041] Preferably, in the scalp preparation, the content of the Chinese medicine composition for preventing hair loss is 5-8wt%.

[0042] Preferably, the auxiliary materials include one or more of a solvent, a stabilizer, a humectant and a preservative; the stabilizer includes disodium EDTA; the humectant includes glycerol; the preservative includes phenoxyethanol and / or methylparaben; and the solvent includes water and / or butylene glycol.

[0043] Preferably, the scalp preparation comprises one or more of shampoo, conditioner, hair mask, scalp essence, hair wax, hair spray, hair perfume, and dry cleaning powder.

[0044] In an embodiment of the present invention, the formula of the scalp essence comprises:

[0045] The Chinese medicine composition for preventing hair loss: 5-8wt%; butylene glycol: 2wt%; glycerol: 0.85wt%; phenoxyethanol: 0.4wt%; disodium EDTA: 0.4wt%; methylparaben: 0.15wt%; the balance is purified water.

[0046] Compared with the prior art, the present invention uses a specific extraction method to extract Chinese medicine, and after combination, a Chinese medicine composition for hair loss prevention is obtained, including Tilia latifolia flower extract, Platycladus orientalis leaf extract, ginger extract and Polygonum indigofera extract, which can improve the hair follicle environment, inhibit hair loss, and inhibit inflammation to a certain extent. It can be seen that the Chinese medicine composition for hair loss prevention of the present invention can play a good hair loss prevention effect, and has low irritation and low toxicity to the human body, is suitable for application in various scalp care cosmetics, and has good industrial application prospects. DETAILED DESCRIPTION

[0047] The technical solution of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0048] In order to further illustrate the present invention, the following examples are used to explain it in detail. The raw materials used in the following examples and comparative examples of the present invention are all commercially available products.

[0049] Example 1

[0050] The Chinese medicinal composition for preventing hair loss of this embodiment is composed of the following components: 20 g of Tilia latifolia flower extract, 70 g of Platycladus orientalis leaf extract, 20 g of Polygonum indigofera extract and 15 g of ginger extract.

[0051] The preparation method of the broadleaf linden flower extract comprises the following steps:

[0052] Take broad-leaved linden flower, add 45wt% ethanol solution, the solid-liquid ratio of broad-leaved linden flower to ethanol solution is 1:10g / mL, extract twice at 60℃, each time for 30min, concentrate under reduced pressure, freeze the product at -18℃ for 24h, and the conditions of sublimation and analytical drying are -10℃, 50Pa, 30℃, 20Pa, respectively, to obtain broad-leaved linden flower extract.

[0053] The preparation method of the above-mentioned Platycladus orientalis leaf extract comprises the following steps:

[0054] The Platycladus orientalis leaves were crushed, immersed in a 45wt% ethanol solution, and refluxed for extraction, with the solid-liquid ratio of Platycladus orientalis leaf powder and ethanol solution being 1:10 g / mL; reflux extraction was performed three times, each extraction time being 20 min, and the temperature being 50°C, to obtain an extract; the extract was ultrasonically treated at 100 W for 20 min, at a temperature of 50°C, and the supernatant was obtained by centrifugation to obtain an extract, which was concentrated under reduced pressure and dried at 80°C for 8 h to obtain a Platycladus orientalis leaf extract.

[0055] The preparation method of the above-mentioned Polygonum indigofera extract comprises the following steps:

[0056] The indigofera was crushed, immersed in a 45wt% ethanol solution, and refluxed for extraction, with the solid-liquid ratio of the indigofera powder to the ethanol solution being 1:10 g / mL; the reflux extraction was performed three times, with each extraction time being 20 min and the temperature being 50°C to obtain an extract, which was concentrated under reduced pressure and dried at 80°C for 8 h to obtain the indigofera extract.

[0057] The preparation method of the ginger extract comprises the following steps:

[0058] The ginger root was crushed, immersed in a 45wt% ethanol solution, and refluxed for extraction. The solid-liquid ratio of the ginger root powder to the ethanol solution was 1:15g / mL. The reflux extraction was performed 3 times, each time for 20min at a temperature of 50°C to obtain an extract, which was concentrated under reduced pressure and dried at 40°C for 20h to obtain a ginger extract.

[0059] The Tilia latifolia flower extract, Platycladus orientalis leaf extract, Polygonum indigofera extract and ginger extract prepared above are mixed to obtain a traditional Chinese medicine composition for preventing hair loss.

[0060] Example 2

[0061] The Chinese medicinal composition for preventing hair loss of this embodiment is composed of the following components: 25 g of Tilia latifolia flower extract, 54 g of Platycladus orientalis leaf extract, 18 g of Polygonum indigofera extract and 20 g of ginger extract.

[0062] Example 3

[0063] The Chinese medicinal composition for preventing hair loss of this embodiment is composed of the following components: 30 g of Tilia latifolia flower extract, 39 g of Platycladus orientalis leaf extract, 20 g of Polygonum indigofera extract and 30 g of ginger extract.

[0064] Comparative Example 1

[0065] The Chinese medicine composition of this comparative example is different from that of Example 1 in that this comparative example only includes Tilia latifolia flower extract, Platycladus orientalis leaf extract and Polygonum indigofera extract; the missing amount of ginger extract is distributed to the corresponding components according to the ratio of the other three substances.

[0066] Comparative Example 2

[0067] The Chinese medicine composition of this comparative example is different from that of Example 1 in that this comparative example only includes broad-leaved linden flower extract, ginger extract and indigofera tinctoria extract; the missing amount of Platycladus orientalis leaf extract is distributed to the corresponding components according to the ratio of the other three substances.

[0068] Comparative Example 3

[0069] The Chinese medicine composition of this comparative example is different from that of Example 1 in that this comparative example only includes Tilia latifolia flower extract, Platycladus orientalis leaf extract and ginger extract; the missing amount of Polygonum indigofera extract is distributed to the corresponding components according to the ratio of the other three substances.

[0070] Comparative Example 4

[0071] The Chinese medicine composition of this comparative example is different from that of Example 1 in that this comparative example only includes ginger extract, Platycladus orientalis leaf extract and Polygonum indigofera extract; the missing amount of Tilia latifolia flower extract is distributed to the corresponding components according to the ratio of the other three substances.

[0072] Comparative Example 5

[0073] The Chinese medicine composition of this comparative example is different from that of Example 1 in that this comparative example only includes ginger extract and Platycladus orientalis leaf extract; the missing amounts of Tilia latifolia flower extract and Polygonum indigofera tinctorius extract are allocated to the corresponding components according to the ratio of the other two substances.

[0074] Comparative Example 6

[0075] The Chinese medicine composition of this comparative example is different from that of Example 1 in that this comparative example only includes Tilia latifolia flower extract and Polygonum indigofera extract; the missing amounts of ginger extract and Platycladus orientalis leaf extract are allocated to the corresponding components according to the ratio of the other two substances.

[0076] Comparative Example 7

[0077] The Chinese medicine composition of this comparative example is different from that of Example 1 in that the preparation method of the Tilia latifolia flower extract of this comparative example comprises the following steps:

[0078] Take broad-leaved linden flower, add 45% (v / v) ethanol, soak for 6 hours, the solid-liquid ratio of broad-leaved linden flower to ethanol is 1:20g / mL, centrifuge to take the supernatant, add 45% ethanol solution, the volume ratio of supernatant to ethanol solution is 1:8, extract twice at 60°C, each time for 30 minutes, concentrate under reduced pressure, and dry the product at 50°C for 12 hours to obtain a broad-leaved linden flower extract.

[0079] The remaining components and preparation methods are carried out with reference to Example 1.

[0080] Application Examples 1-3

[0081] The Chinese herbal composition for preventing hair loss prepared in the embodiment is made into a scalp essence, and the formula of the scalp essence consists of the following components: 8wt% of the Chinese herbal composition for preventing hair loss; 2wt% of butylene glycol; 0.85wt% of glycerol; 0.4wt% of phenoxyethanol; 0.4wt% of disodium EDTA; 0.15wt% of methylparaben; and the balance is purified water.

[0082] Application Comparative Examples 1-7

[0083] The Chinese medicine composition obtained in the comparative example is made into a scalp essence, and the formula of the scalp essence consists of the following components: Chinese medicine composition: 8wt%; butylene glycol: 2wt%; glycerol: 0.85wt%; phenoxyethanol: 0.4wt%; disodium EDTA: 0.4wt%; methylparaben: 0.15wt%; and the balance is purified water.

[0084] Test Example 1

[0085] 7-week-old SPF male C57BL / 6 mice weighing 18-20g were taken, anesthetized, and the hair on the back of the mice was shaved to induce the development of highly synchronized growth phase hair follicles. On the 9th day after hair removal, 80mg / kg of 10mg / ml cyclophosphamide solution was injected intraperitoneally into the mice to induce apoptosis of all growth phase hair follicles, thereby inducing hair loss after chemotherapy.

[0086] 18 depilated mice were randomly divided into 3 groups, 6 mice in each group: model group, embodiment group, and comparative group. The model group was given normal saline; the dosage of the embodiment group and the comparative group was 2g / mouse. Each time the drug was administered, the Chinese medicine composition was dissolved in a small amount of normal saline and applied to the depilated area with a cotton swab; from the second day after depilation, the drug was administered once a day, and continued to be administered until the fifth day after cyclophosphamide modeling, for a total of 13 days.

[0087] After 7 days of cyclophosphamide modeling, the hair growth of each group was recorded and the proportion of the remaining hair area to the total hair removal area was calculated. The test results are shown in Table 1.

[0088] Table 1

[0089] Group Remaining hair area percentage (%) Model Group 26.4 Example 1 58.9 Example 2 60.2 Example 3 61.3 Comparative Example 1 49.7 Comparative Example 2 48.1 Comparative Example 3 42.6 Comparative Example 4 43.9 Comparative Example 5 42.7 Comparative Example 6 47.5 Comparative Example 7 50.3

[0090] It can be seen from Table 1 that, compared with the comparative example, the Chinese medicine composition provided in the embodiment of the present invention can significantly alleviate hair loss caused by chemotherapy drugs.

[0091] Test Example 2

[0092] 90 volunteers with symptoms of infectious alopecia and more than 50 hairs lost per day were selected to participate in the test, and randomly divided into 9 groups. The products prepared by the application examples and the comparative examples were used as the test group, and a control group (normal saline) was added. The corresponding products were used once at a fixed time every day; the hair lost in each group was collected on the 0th, 20th and 45th days, and the average value was taken. The test results are shown in Table 2.

[0093] Table 2

[0094]

[0095]

[0096] It can be seen from Table 2 that, compared with the comparative example, the product provided by the application example of the present invention has a better anti-hair loss effect after 45 days of use.

[0097] Test Example 3

[0098] This test example explores the inhibitory effect of the Chinese medicine composition obtained in the embodiment and the comparative example on inflammatory factors, and specifically includes the following steps:

[0099] (1) Take BMDMs cells in the logarithmic growth phase and inoculate them into 6-well cell culture plates. Incubate at 37°C and 5% CO 2 The cells were cultured in an incubator for 12 h, and LPS (100 ng / mL) was added to induce for 24 h to differentiate into a classical activated pro-inflammatory macrophage model (BMDM-M1); PBS was added to undifferentiated macrophages (BMDM-M0) as a control group.

[0100] (2) The compositions obtained in the examples and comparative examples were added to the inflammatory cell model BMDM-M1, respectively, and cultured for 24 hours. The cells and cell supernatants of each group were collected, and the concentration changes of pro-inflammatory factors TNF-α and IL-1β in the cell supernatants were detected by ELISA. The test results are shown in Table 3.

[0101] Table 3

[0102]

[0103]

[0104] It can be seen from Table 3 that, compared with the comparative example, the Chinese medicine composition provided by the embodiment of the present invention can significantly inhibit the anti-inflammatory factors TNF-α and IL-1β.

Claims

1. A Chinese medicine composition for preventing hair loss, characterized in that: The invention comprises, by weight: 10 to 30 parts of Tilia latifolia flower extract, 30 to 80 parts of Platycladus orientalis leaf extract, 10 to 20 parts of Polygonum indigofera extract and 5 to 30 parts of ginger extract.

2. The Chinese medicine composition for preventing hair loss according to claim 1, characterized in that: The preparation method of the Tilia latifolia flower extract comprises: The broad-leaved linden flower is crushed, mixed with an ethanol solution, extracted at 50-60° C. for 1-2 hours, concentrated under reduced pressure, and freeze-dried to obtain a broad-leaved linden flower extract; The solid-liquid ratio of the broadleaf linden flower to the ethanol solution is 1:(10-25) g / mL; In the ethanol solution, the volume fraction of ethanol is 45% to 60%.

3. The Chinese medicine composition for preventing hair loss according to claim 1, characterized in that: The preparation method of the Platycladus orientalis leaf extract comprises: The Platycladus orientalis leaves are mixed with a solvent to obtain an extract, and the extract is subjected to ultrasonication, concentration and drying to obtain the Platycladus orientalis leaf extract.

4. The Chinese medicine composition for preventing hair loss according to claim 1, characterized in that: The preparation method of the Polygonum indigofera extract comprises: The indigofera tinctoria is mixed with a solvent to obtain an extract, and the extract is concentrated and dried to obtain the indigofera tinctoria extract.

5. The Chinese medicine composition for preventing hair loss according to claim 1, characterized in that: The preparation method of the ginger extract comprises: The ginger root is mixed with a solvent to obtain an extract, and the extract is concentrated and dried to obtain a ginger extract.

6. The Chinese medicine composition for preventing hair loss according to claim 1, characterized in that: The composition comprises, by weight: 20 parts of Tilia latifolia flower extract, 70 parts of Platycladus orientalis leaf extract, 20 parts of Polygonum indigofera extract, and 15 parts of ginger extract; Alternatively, the Chinese medicine composition for preventing hair loss comprises, by weight: 25 parts of Tilia latifolia flower extract, 54 parts of Platycladus orientalis leaf extract, 18 parts of Polygonum indigofera extract, and 20 parts of ginger extract; Alternatively, the Chinese herbal composition for preventing hair loss comprises, in parts by mass: 30 parts of Tilia latifolia flower extract, 39 parts of Platycladus orientalis leaf extract, 20 parts of Polygonum indigofera extract, and 30 parts of ginger extract.

7. The method for preparing the Chinese medicine composition for preventing hair loss according to any one of claims 1 to 6, characterized in that: include: By weight, 10 to 30 parts of Tilia latifolia flower extract, 30 to 80 parts of Platycladus orientalis leaf extract, 10 to 20 parts of Polygonum indigofera extract and 5 to 30 parts of ginger extract are mixed to obtain a traditional Chinese medicine composition for preventing hair loss.

8. Use of the Chinese medicine composition for preventing hair loss according to any one of claims 1 to 6 in inhibiting inflammatory factors.

9. A scalp preparation, characterized in that The invention comprises the Chinese medicine composition for preventing hair loss according to any one of claims 1 to 6, and acceptable auxiliary materials.

10. The scalp preparation according to claim 9, characterized in that The auxiliary materials include one or more of solvents, stabilizers, humectants and preservatives.

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