Automatic sampling system of continuous flow reactor and working method of automatic sampling system

Abstract

The invention belongs to the technical field of mixing, and particularly relates to an automatic sampling system for a continuous flow reactor and a working method thereof.The automatic sampling system for the continuous flow reactor comprises a multi-station sampling disc, a plurality of automatic sampling devices, a plurality of automatic sampling devices and a controller, the plurality of material conveying assemblies are respectively used for conveying corresponding materials; the sampling needle is connected with each material conveying assembly; the control module is electrically connected with the material conveying assemblies and is configured to control the corresponding material conveying assemblies to inject the required amount of materials into the corresponding sampling bottles through the sampling needles, and the automatic sampling system of the continuous flow reactor periodically works through the negative pressure mechanism and is matched with the sampling bottles, so that the materials in the micro-reaction channel move back and forth.

Description

Technical Field

[0001] The invention belongs to the technical field of mixing, and in particular relates to an automatic adopting system for a continuous flow reactor and a working method thereof. Background Art

[0002] In order to mix multiple materials, it is necessary to pour each material from the inlet of the micro-reaction chip, then mix them in the micro-reaction channel, and then discharge them from the outlet of the micro-reaction chip, so as to achieve the mixing effect of the materials; in the related technology, the flow of materials mostly uses a pump as a power source. Under this driving mode, the flow direction of the material is single, and multiple feed ports are used to correspond to different materials. After each material is mixed and reacted in the micro-reaction channel, it is discharged from a discharge port. Therefore, it is suitable for the production stage. The amount of each material used is large and multiple mixing is not required.

[0003] However, during the experimental stage, not only was the amount of each material used small, but the number of material types was also uncertain, so the micro-reaction channel with a fixed number of feed ports was not applicable; at the same time, the micro-reaction channel with only a single discharge port could not be connected to multiple feed ports to circulate the mixed material, resulting in the inability to continue the mixing reaction.

[0004] Therefore, how to solve the problem that the existing micro-reaction chip using multiple feed ports and a single discharge port cannot achieve continuous mixing reaction in the experimental stage is urgently needed to be solved by those skilled in the art.

[0005] It should be noted that the above information disclosed in this background technology section is only used to understand the background technology of the present application concept, and therefore, the above description is not considered to constitute information of the prior art. Summary of the invention

[0006] The embodiments of the present disclosure at least provide a continuous flow reactor automatic adoption system and a working method thereof.

[0007] In the first aspect, an embodiment of the present disclosure provides an automatic sampling system for a continuous flow reactor, which includes: a multi-station sampling plate, on which a plurality of mounting slots for plugging in sampling bottles are provided; a plurality of material conveying components, each used to convey a corresponding material; a sampling needle, connected to each material conveying component; and a control module, electrically connected to the material conveying component and configured to control the corresponding material conveying component to inject a required amount of material into the corresponding sampling bottle through the sampling needle.

[0008] In an optional embodiment, a sealed micro-reaction channel is provided in the multi-station sampling disk, and the micro-reaction channel is provided with a discharge port and a plurality of feed ports; wherein each of the feed ports extends to a corresponding mounting groove; and each of the feed ports is provided with an independent solenoid valve, each solenoid valve is electrically connected to a control module, and the control module is configured to control the corresponding solenoid valve to open when a sampling bottle is inserted into the mounting groove.

[0009] In an optional embodiment, the micro-reaction channel is spiral; wherein the outermost circle of the micro-reaction channel is connected to each feed port; and the micro-reaction channel gradually rises in height as it extends toward the center so that the discharge port is higher than each feed port.

[0010] In an optional embodiment, a material receiving bin is provided in the center of the multi-station sampling disk; wherein the bottom of the material receiving bin is connected to the discharge port of the micro-reaction channel; and the material receiving bin is connected to a negative pressure mechanism, which is suitable for causing the liquid in the micro-reaction channel to flow through negative pressure.

[0011] In an optional embodiment, a receiving plate is provided on one side of the multi-station sampling tray, and the receiving plate is used to hold a sampling bottle, and the sampling bottle includes a liquid filling port; wherein the control module is configured to control the sampling needle to inject material into the sampling bottle on the receiving plate.

[0012] In an optional embodiment, the control module is electrically connected to the negative pressure mechanism and is configured to control the periodic operation of the negative pressure mechanism; wherein when the negative pressure mechanism is working, the negative pressure in the material receiving bin is used to guide the materials in each sampling bottle to enter the micro-reaction channel and flow toward the material receiving bin for mixing; and when the negative pressure mechanism stops working, the negative pressure in each sampling bottle is used to guide the materials in the material receiving bin to enter the micro-reaction channel and flow toward the sampling bottle for mixing.

[0013] In an optional embodiment, the multi-station sampling plate includes: a base and an upper cover; wherein the micro-reaction channel is opened on the upper surface of the base; and the upper cover is attached to the base to cover the micro-reaction channel.

[0014] In an optional embodiment, a plurality of flow guide member groups are arranged on the upper cover, and each of the flow guide member groups is arranged along the projection of the micro-reaction channel so as to extend into the micro-reaction channel when the upper cover and the base are covered.

[0015] In an optional embodiment, the guide member group includes: a first guide member and a second guide member; wherein the first guide member is in the shape of a water droplet and the second guide member is in the shape of a fish fin; in the process of the mixed liquid flowing toward the receiving bin, the first guide member diverts the mixed liquid so that one stream of the mixed liquid is guided by the second guide member and then collides with another stream of the mixed liquid; and in the process of the mixed liquid flowing toward the sampling bottle, the second guide member guides the mixed liquid to avoid direct colliding with the first guide member to reduce flow resistance.

[0016] In the second aspect, the embodiments of the present disclosure also provide a working method of the automatic sampling system of the continuous flow reactor as described above, which includes: plugging the sampling bottle through the multi-station sampling plate; conveying the material through the material conveying component; controlling the corresponding material conveying component through the control module to inject the required amount of material into the corresponding sampling bottle through the sampling needle.

[0017] The beneficial effect of the present invention is that the continuous flow reactor automatically adopts a negative pressure source as the driving force for the flow of materials in the micro-reaction channel, so that the negative pressure can cause the loss of materials in each sampling bottle to form a negative pressure in the process of the material moving toward the receiving bin due to the negative pressure, that is, when the negative pressure in the receiving bin stops and the normal pressure is restored, the material will move toward the sampling bottle due to the negative pressure of the sampling bottle; when the negative pressure mechanism connected to the receiving bin works again, the material moves toward the receiving bin again, so that the material can be reciprocated and mixed in the micro-reaction channel through the periodic operation of the negative pressure mechanism, thereby realizing a continuous flow mixing reaction.

[0018] Other features and advantages of the present invention will be described in the following description, and partly become apparent from the description, or understood by practicing the present invention. The purpose and other advantages of the present invention are realized and obtained by the structures particularly pointed out in the description, claims and drawings.

[0019] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, this article specifically cites preferred embodiments and provides detailed descriptions as follows in conjunction with the attached drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the specific implementation methods of the present invention or the technical solutions in the prior art, the drawings required for use in the specific implementation methods or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some implementation methods of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0021] Figure 1 A schematic diagram of the structure of an automatic adoption system for a continuous flow reactor provided in an embodiment of the present disclosure; Figure 2A schematic diagram of the structure of a base in a multi-station sampling tray provided in an embodiment of the present disclosure; Figure 3 A schematic diagram of the structure of the base and the upper cover of a multi-station sampling tray provided in an embodiment of the present disclosure; Figure 4 A schematic diagram of the structure of a sampling bottle plugged into a mounting slot provided by an embodiment of the present disclosure; Figure 5 A schematic structural diagram of a flow guide assembly on an upper cover provided in an embodiment of the present disclosure; Figure 6 A schematic diagram of a material flowing toward a receiving bin when a micro-reaction channel is straightened provided in an embodiment of the present disclosure; Figure 7 A schematic diagram of a material flowing toward a sampling bottle when a micro-reaction channel is straightened provided in an embodiment of the present disclosure.

[0022] In the figure: Multi-station sampling plate 1, mounting slot 11, micro-reaction channel 12, discharge port 121, feed port 122, receiving bin 13, base 14, upper cover 15, flow guide assembly 16, first flow guide 161, second flow guide 162; Sampling bottle 2, liquid injection port 21; Material conveying component 3; Sampling needle 4; Negative pressure mechanism 5. DETAILED DESCRIPTION

[0023] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution of the present invention will be clearly and completely described below in conjunction with the accompanying drawings. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0024] It should be noted that similar reference numerals and letters represent similar items in the following drawings, so once an item is defined in one drawing, it does not need to be further defined and explained in the subsequent drawings. In addition, in the drawings, the thickness of the components may be exaggerated or reduced in order to effectively describe the technical content.

[0025] Some embodiments of the present invention are described in detail below in conjunction with the accompanying drawings. In the absence of conflict, the following embodiments and features in the embodiments can be combined with each other.

[0026] like Figure 1As shown, at least one embodiment provides an automatic adoption system for a continuous flow reactor, which includes: a multi-station sampling plate 1, on which are provided a plurality of mounting slots 11 for plugging in sampling bottles 2; a plurality of material conveying components 3, each used to convey a corresponding material; a sampling needle 4, connected to each material conveying component 3; and a control module, electrically connected to the material conveying component 3, and configured to control the corresponding material conveying component 3 to inject a required amount of material into the corresponding sampling bottle 2 through the sampling needle 4.

[0027] In this embodiment, the control module is electrically connected to the display. During the batching process, you only need to select the required raw materials on the display and enter the required dosage, so that the sampling needle 4 can inject the material to be mixed into the corresponding sampling bottle 2; the material is transported by the sampling pump, and the control module is electrically connected to the sampling pump in the material conveying component 3.

[0028] like Figure 1 , Figure 2 As shown, in some embodiments, a sealed micro-reaction channel 12 is provided in the multi-station sampling disk 1, and the micro-reaction channel 12 is provided with an outlet 121 and a plurality of feed ports 122; wherein each of the feed ports 122 extends to a corresponding mounting slot 11 respectively; and each of the feed ports 122 is provided with an independent solenoid valve, and each solenoid valve is electrically connected to a control module, and the control module is configured to control the corresponding solenoid valve to open when the sampling bottle 2 is inserted into the mounting slot 11.

[0029] In this embodiment, when the sampling bottle 2 is not inserted into the installation groove 11 , the discharge port 121 in the installation groove 11 is closed, so that the micro-reaction channel 12 is sealed.

[0030] like Figure 3 , Figure 4 As shown, in some embodiments, a receiving plate (the receiving plate is not shown in the figure) is provided on one side of the multi-station sampling tray 1, and the receiving plate is used to hold the sampling bottle 2, and the sampling bottle 2 includes a liquid filling port 21; wherein the control module is configured to control the sampling needle 4 to inject material into the sampling bottle 2 on the receiving plate.

[0031] Specifically, a number of empty sampling bottles 2 are arranged on the receiving plate, and the sampling bottle 2 has only one liquid injection port 21, and a membrane is arranged inside the liquid injection port 21 to prevent the material from flowing out; after the material is injected into the sampling bottle 2, the operator takes the sampling bottle 2 out of the receiving plate, inserts it upside down into the mounting groove 11 of the multi-station sampling disk 1, so that the liquid injection port 21 of the sampling bottle 2 is inserted into the feed port 122 in the mounting groove 11, and at this time, the solenoid valve in the feed port 122 is triggered to open, so that the sampling bottle 2 is connected with the micro-reaction channel 12; wherein, the opening of the solenoid valve can send a signal through a pressure sensor or a distance sensor, etc.

[0032] like Figures 1 to 3 As shown, in some embodiments, the micro-reaction channel 12 is spiral-shaped; a material receiving bin 13 is provided at the center of the multi-station sampling disk 1; wherein the bottom of the material receiving bin 13 is connected to the discharge port 121 of the micro-reaction channel 12; and the material receiving bin 13 is connected to a negative pressure mechanism 5, which is suitable for making the liquid in the micro-reaction channel 12 flow through negative pressure.

[0033] In some embodiments, the control module is electrically connected to the negative pressure mechanism 5 and is configured to control the periodic operation of the negative pressure mechanism 5; wherein when the negative pressure mechanism 5 is working, the negative pressure in the material receiving bin 13 is used to guide the materials in each sampling bottle 2 to enter the micro-reaction channel 12 and flow toward the material receiving bin 13 for mixing; and when the negative pressure mechanism 5 stops working, the negative pressure in each sampling bottle 2 is used to guide the materials in the material receiving bin 13 to enter the micro-reaction channel 12 and flow toward the sampling bottle 2 for mixing.

[0034] Specifically, a negative pressure source is used as the driving force for the flow of materials in the micro-reaction channel 12. In the process of the material moving toward the receiving bin 13 due to the negative pressure, negative pressure is also formed in each sampling bottle 2 due to the loss of material. That is, when the negative pressure in the receiving bin 13 stops and the normal pressure is restored, the material will move toward the sampling bottle 2 due to the negative pressure of the sampling bottle 2; when the negative pressure mechanism 5 connected to the receiving bin 13 works again, the material moves toward the receiving bin 13 again, so that the material is reciprocated and mixed in the micro-reaction channel 12 through the periodic operation of the negative pressure mechanism 5, thereby realizing a continuous flow mixing reaction; at the same time, it is ensured that the required material can be conveniently added to the micro-reaction channel 12 during the experiment.

[0035] In some embodiments, the outermost circle of the micro-reaction channel 12 is connected to each feed port 122 ; and the micro-reaction channel 12 gradually increases in height during its extension toward the center, so that the discharge port 121 is higher than each feed port 122 .

[0036] Specifically, the micro-reaction channel 12 gradually increases in height as it extends toward the center, so as to facilitate the movement of the mixed material toward the sampling bottle 2 .

[0037] In some embodiments, the material receiving bin 13 is connected to the discharge port 121 of the micro-reaction channel 12 through an inlet pipe, and a stop valve is provided on the inlet pipe of the material receiving bin 13. After the material is mixed in the micro-reaction channel 12 for a certain period of time, the negative pressure mechanism 5 is controlled to work until all the materials in the micro-reaction channel 12 are sucked into the material receiving bin 13, and then the stop valve is closed, and the inlet pipe of the material receiving bin 13 is separated from the discharge port 121 of the micro-reaction channel 12, so as to collect the mixed material in the material receiving bin 13.

[0038] like Figure 3As shown, in some embodiments, the multi-station sampling tray 1 includes: a base 14 and an upper cover 15; wherein the micro-reaction channel 12 is opened on the upper surface of the base 14; and the upper cover 15 is attached to the base 14 to cover the micro-reaction channel 12.

[0039] like Figure 5 As shown, in some embodiments, a plurality of guide member groups 16 are disposed on the upper cover 15 , and each of the guide member groups 16 is arranged along the projection of the micro reaction channel 12 so as to extend into the micro reaction channel 12 when the upper cover 15 and the base 14 are covered.

[0040] Specifically, the upper cover 15 and the base 14 are spliced ​​together to facilitate the processing of the micro-reaction channel 12 and the flow guide assembly 16 .

[0041] like Figure 6 , Figure 7 As shown, in some embodiments, the guide member group 16 includes: a first guide member 161 and a second guide member 162; wherein the first guide member 161 is in the shape of a water droplet, and the second guide member 162 is in the shape of a fish fin; in the process of the mixed liquid flowing toward the receiving bin 13, the first guide member 161 diverts the mixed liquid, so that one stream of the mixed liquid is guided by the second guide member 162 and then collides with another stream of the mixed liquid; and in the process of the mixed liquid flowing toward the sampling bottle 2, the second guide member 162 guides the mixed liquid to avoid direct colliding with the first guide member 161, so as to reduce the flow resistance.

[0042] In this embodiment, when the material flows toward the sampling bottle 2, Figure 6 As shown, due to the existence of the negative pressure mechanism 5, the suction force is very large, so the material can be divided into two streams for collision and sufficient mixing reaction; and during the flow of the material toward the sampling bottle 2, as shown in FIG. Figure 7 As shown, the suction force of the sampling bottle 2 is relatively small, so the resistance is reduced to facilitate the flow of materials.

[0043] At least one embodiment also provides a working method of an automatic system for a continuous flow reactor, which includes: plugging a sampling bottle 2 through a multi-station sampling tray 1; conveying materials through a material conveying component 3; and controlling a corresponding material conveying component 3 through a sampling needle 4 through a control module to inject a required amount of material into a corresponding sampling bottle 2.

[0044] For the specific structure and implementation process of the automatic adoption system for the continuous flow reactor, please refer to the relevant discussion in the above embodiments, which will not be repeated here.

[0045] To sum up, the continuous flow reactor automatically adopts a negative pressure source as the driving force for the flow of materials in the micro-reaction channel 12. In the process of the material moving toward the receiving bin 13 due to the negative pressure, negative pressure is also formed in each sampling bottle 2 due to the loss of material. That is, when the negative pressure in the receiving bin 13 stops and the normal pressure is restored, the material will move toward the sampling bottle 2 due to the negative pressure; when the negative pressure mechanism 5 connected to the receiving bin 13 works again, the material moves toward the receiving bin 13 again, so that through the periodic operation of the negative pressure mechanism 5, the material is reciprocated and mixed in the micro-reaction channel 12, thereby realizing a continuous flow mixing reaction.

[0046] Herein, when it is mentioned that a first component is located on a second component, this may mean that the first component may be directly formed on the second component, or a third component may be interposed between the first component and the second component.

[0047] In this article, when an element or layer is referred to as being "located on," "engaged to," "connected to," "attached to," or "coupled to" another element or layer, it may be directly located on, engaged, connected, attached to, or coupled to another element or layer, or there may be intermediate elements or layers. In contrast, when an element is referred to as being "directly on," "directly engaged to," "directly connected to," "directly attached to," or "directly coupled to" another element or layer, there may be no intermediate elements or layers. Other words used to describe the relationship between elements should be interpreted in a similar manner (e.g., "between" versus "directly between," "adjacent" versus "directly adjacent," etc.). As used herein, the term "and / or" includes any and all combinations of one or more of the associated listed items.

[0048] Herein, example embodiments of the present disclosure will be described in more detail with reference to the accompanying drawings. As used herein, expressions such as "at least one of..." modify the entire list of elements when following a list of elements, rather than modifying individual elements in the list. For example, the expression "at least one of a, b, and c" should be understood to include only a, only b, only c, both a and b, both a and c, both b and c, or all of a, b, and c.

[0049] The terms used herein are only used to describe specific exemplary configurations and are not intended to be limited. As used herein, the singular articles "one", "an" and "the" may also be intended to include plural forms, unless it is clearly indicated above that this is not the case. The terms "comprise", "include" and "have" are inclusive, and therefore specify the presence of features, steps, operations, elements and / or components, but do not exclude the presence or addition of one or more other features, steps, operations, elements, components and / or combinations thereof. The method steps, processes and operations described herein should not be interpreted as necessarily requiring them to be performed in the specific order discussed or shown, unless specifically identified as an execution order. Additional or alternative steps may be adopted.

[0050] As used herein, the phrases "in one embodiment," "according to one embodiment," "in some embodiments," and the like generally refer to the fact that the particular feature, structure, or characteristic following the phrase may be included in at least one embodiment of the present disclosure. Therefore, a particular feature, structure, or characteristic may be included in more than one embodiment of the present disclosure, so that these phrases do not necessarily refer to the same embodiment. As used herein, the terms "example," "exemplary," and the like are used to "serve as an example, instance, or illustration." Any implementation, aspect, or design described herein as "example" or "exemplary" is not necessarily to be construed as preferred or superior to other implementations, aspects, or designs. On the contrary, the use of the terms "example," "exemplary," and the like is intended to present concepts in a concrete manner.

[0051] In the description of the embodiments of the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0052] In the description of the present invention, it should be noted that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inside", "outside", etc. is based on the orientation or positional relationship shown in the drawings, which is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation of the present invention. In addition, terms such as "first", "second" and other numerical terms do not imply an order or sequence when used in this document unless explicitly indicated above. Therefore, without departing from the teachings of the example embodiments, the first element, component, region, layer or section discussed above may be referred to as a second element, component, region, layer or section.

[0053] Spatially relative terms, such as "inside", "outside", "below", "below", "down", "above", "on", etc., may be used herein to facilitate description of the relationship of one element or feature to another element or feature as illustrated in the figure. In addition to the orientation depicted in the figure, spatially relative terms may be intended to cover different orientations of the device in use or operation. For example, if the device in the figure is turned over, the elements described as "below" or "below" other elements or features will be oriented to be "above" other elements or features. Therefore, the example term "below" can cover the orientation above and below. The device can be oriented in other ways (rotated 90 degrees or in other orientations), and the spatially relative descriptors used herein are interpreted accordingly.

[0054] In the above discussion, unless otherwise stated, the terms "about," "approximately," "substantially," etc., when used to describe a numerical value, mean a variation of + / - 10% of the value.

[0055] Based on the above ideal embodiments of the present invention, the relevant staff can make various changes and modifications without departing from the technical concept of the present invention through the above description. The technical scope of the present invention is not limited to the contents of the specification, and its technical scope must be determined according to the scope of the claims.

Claims

1. A continuous flow reactor automatic use system, characterized in that: include: A multi-station sampling plate (1) having a plurality of mounting slots (11) for inserting sampling bottles (2); A plurality of material conveying components (3), each used for conveying a corresponding material; A sampling needle (4) connected to each material conveying component (3); and The control module is electrically connected to the material conveying component (3) and is configured to control the corresponding material conveying component (3) to inject a required amount of material into the corresponding sampling bottle (2) through the sampling needle (4).

2. The continuous flow reactor automatic use system according to claim 1, characterized in that: A sealed micro-reaction channel (12) is provided in the multi-station sampling disk (1), and the micro-reaction channel (12) is provided with a discharge port (121) and a plurality of feed ports (122); wherein Each of the feed ports (122) extends to a corresponding mounting slot (11); and An independent solenoid valve is provided in each of the feed ports (122), and each solenoid valve is electrically connected to a control module. The control module is configured to control the corresponding solenoid valve to open when a sampling bottle (2) is inserted into the mounting slot (11).

3. The automatic use system of a continuous flow reactor as claimed in claim 2, characterized in that: The micro-reaction channel (12) is spiral-shaped; wherein The outermost circle of the micro-reaction channel (12) is connected to each feed port (122); and The micro-reaction channel (12) gradually increases in height during its extension towards the center, so that the discharge port (121) is higher than each feed port (122).

4. The continuous flow reactor automatic use system as claimed in claim 3, characterized in that: A material receiving bin (13) is provided at the center of the multi-station sampling plate (1); wherein The bottom of the material receiving bin (13) is connected to the material outlet (121) of the micro-reaction channel (12); and The material receiving bin (13) is connected to a negative pressure mechanism (5) suitable for causing the liquid in the micro-reaction channel (12) to flow through negative pressure.

5. The automatic use system of a continuous flow reactor as claimed in claim 4, characterized in that: A receiving plate is provided on one side of the multi-station sampling tray (1), and the receiving plate is used to hold a sampling bottle (2), wherein the sampling bottle (2) comprises a liquid injection port (21); The control module is configured to control the sampling needle (4) to inject material into the sampling bottle (2) on the receiving plate.

6. The continuous flow reactor automatic use system according to claim 5, characterized in that: The control module is electrically connected to the negative pressure mechanism (5) and is configured to control the negative pressure mechanism (5) to operate periodically; wherein When the negative pressure mechanism (5) is in operation, negative pressure is created in the material receiving bin (13) to guide the materials in each sampling bottle (2) into the micro-reaction channel (12) to flow toward the material receiving bin (13) for mixing; and When the negative pressure mechanism (5) stops working, the negative pressure in each sampling bottle (2) guides the material in the material receiving bin (13) to enter the micro-reaction channel (12) and flow toward the sampling bottle (2) for mixing.

7. The continuous flow reactor automatic use system according to claim 6, characterized in that: The multi-station sampling tray (1) comprises: a base (14) and an upper cover (15); wherein The micro-reaction channel (12) is opened on the upper surface of the base (14); The upper cover (15) is fitted onto the base (14) to cover the micro-reaction channel (12).

8. The continuous flow reactor automatic use system according to claim 7, characterized in that: A plurality of flow guide member groups (16) are provided on the upper cover (15), and each of the flow guide member groups (16) is arranged along the projection of the micro-reaction channel (12) so as to extend into the micro-reaction channel (12) when the upper cover (15) and the base (14) are closed.

9. The continuous flow reactor automatic use system according to claim 8, characterized in that: The flow guide member group (16) comprises: a first flow guide member (161) and a second flow guide member (162); wherein The first flow guide (161) is in the shape of a water drop, and the second flow guide (162) is in the shape of a fish fin; In the process of the mixed liquid flowing toward the receiving bin (13), the first flow guide (161) divides the mixed liquid so that one stream of the mixed liquid is directed by the second flow guide (162) and then offsets another stream of the mixed liquid; and When the mixed liquid flows toward the sampling bottle (2), the second flow guide member (162) guides the mixed liquid to avoid direct collision with the first flow guide member (161), thereby reducing flow resistance.

10. A method for operating the automatic adoption system of a continuous flow reactor as claimed in claim 1, characterized in that: include: Inserting the sampling bottle (2) through the multi-station sampling tray (1); conveying materials through the material conveying component (3); The control module controls the corresponding material conveying component (3) to inject a required amount of material into the corresponding sampling bottle (2) through the sampling needle (4).

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